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Horst Fischer

Research Profile

Chemicals & Drugs

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Cystic Fibrosis

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Publications

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Do-Yeon Cho; Justin A Edward; Dawn T Bravo; Peter H Hwang; Beate Illek; Wei Le; Jayakar V Nayak; Alan Nguyen; Horst Fischer
Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.
David Iovannisci; Beate Illek; Horst Fischer
Function of the HVCN1 proton channel in airway epithelia and a naturally occurring mutation, M91T.
Philip L Ballard; Jae W Lee; Xiaohui Fang; Cheryl Chapin; Lennell Allen; Mark Segal; Horst Fischer; Beate Illek; Linda W Gonzales; Venkatadri Kolla; Michael A Matthay
Regulated gene expression in cultured type II cells of adult human lung.

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All Publications

2013: Do-Yeon Cho; Justin A Edward; Dawn T Bravo; Peter H Hwang; Beate Illek; Wei Le; Jayakar V Nayak; Alan Nguyen; Horst Fischer
Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.
International forum of allergy & rhinology 2013;3(5):376-83.
2010: David Iovannisci; Beate Illek; Horst Fischer
Function of the HVCN1 proton channel in airway epithelia and a naturally occurring mutation, M91T.
The Journal of general physiology 2010;136(1):35-46.
2010: Philip L Ballard; Jae W Lee; Xiaohui Fang; Cheryl Chapin; Lennell Allen; Mark Segal; Horst Fischer; Beate Illek; Linda W Gonzales; Venkatadri Kolla; Michael A Matthay
Regulated gene expression in cultured type II cells of adult human lung.
American journal of physiology. Lung cellular and molecular physiology 2010;299(1):L36-50.
2010: Beate Illek; Dachuan Lei; Horst Fischer; Dieter C Gruenert
Sensitivity of chloride efflux vs. transepithelial measurements in mixed CF and normal airway epithelial cell populations.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2010;26(6):983-90.
2009: Horst Fischer
Mechanisms and function of DUOX in epithelia of the lung.
Antioxidants & redox signaling 2009;11(10):2453-65.
2008: Christian Schwarzer; Horst Fischer; Eun-Jin Kim; Katharine J Barber; Aaron D Mills; Mark J Kurth; Dieter C Gruenert; Jung H Suh; Terry E Machen; Beate Illek
Oxidative stress caused by pyocyanin impairs CFTR Cl(-) transport in human bronchial epithelial cells.
Free radical biology & medicine 2008;45(12):1653-62.
2008: Christian Schwarzer; Zhu Fu; Horst Fischer; Terry E Machen
Redox-independent activation of NF-kappaB by Pseudomonas aeruginosa pyocyanin in a cystic fibrosis airway epithelial cell line.
The Journal of biological chemistry 2008;283(40):27144-53.
2008: Beate Illek; Rosalie Maurisse; Logan Wahler; Karl Kunzelmann; Horst Fischer; Dieter C Gruenert
Cl transport in complemented CF bronchial epithelial cells correlates with CFTR mRNA expression levels.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2008;22(1-4):57-68.
2007: Christian Schwarzer; Beate Illek; Jung H Suh; S James Remington; Horst Fischer; Terry E Machen
Organelle redox of CF and CFTR-corrected airway epithelia.
Free radical biology & medicine 2007;43(2):300-16.
2007: Horst Fischer; Linda K Gonzales; Venkatadri Kolla; Christian Schwarzer; Françoise Miot; Beate Illek; Philip L Ballard
Developmental regulation of DUOX1 expression and function in human fetal lung epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2007;292(6):L1506-14.
2007: Horst Fischer; Beate Illek; Walter E Finkbeiner; Jonathan H Widdicombe
Basolateral Cl channels in primary airway epithelial cultures.
American journal of physiology. Lung cellular and molecular physiology 2007;292(6):L1432-43.
2007: Vincent Gaggioli; Christian Schwarzer; Horst Fischer
Expression of Nox1 in 3T3 cells increases cellular acid production but not proton conductance.
Archives of biochemistry and biophysics 2007;459(2):189-96.
2006: Horst Fischer; Jonathan H Widdicombe
Mechanisms of acid and base secretion by the airway epithelium.
The Journal of membrane biology 2006;211(3):139-50.
2005: Maximilian Schuier; Helmut Sies; Beate Illek; Horst Fischer
Cocoa-related flavonoids inhibit CFTR-mediated chloride transport across T84 human colon epithelia.
The Journal of nutrition 2005;135(10):2320-5.
2004: Christian Schwarzer; Terry E Machen; Beate Illek; Horst Fischer
NADPH oxidase-dependent acid production in airway epithelial cells.
The Journal of biological chemistry 2004;279(35):36454-61.
2004: Horst Fischer; Terry E Machen; Jonathan H Widdicombe; Thomas J S Carlson; Steven R King; John W S Chow; Beate Illek
A novel extract SB-300 from the stem bark latex of Croton lechleri inhibits CFTR-mediated chloride secretion in human colonic epithelial cells.
Journal of ethnopharmacology 2004;93(2-3):351-7.
2004: Horst Fischer; Christian Schwarzer; Beate Illek
Vitamin C controls the cystic fibrosis transmembrane conductance regulator chloride channel.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(10):3691-6.
2003: Nancy C Chung; Beate Illek; Jonathan H Widdicombe; Horst Fischer
Measurement of nasal potential difference in mild asthmatics.
Chest 2003;123(5):1467-71.
2002: Horst Fischer; Jonathan H Widdicombe; Beate Illek
Acid secretion and proton conductance in human airway epithelium.
American journal of physiology. Cell physiology 2002;282(4):C736-43.
2001: Horst Fischer; N Fukuda; Pascal Barbry; Beate Illek; Claudio Sartori; Michael A Matthay
Partial restoration of defective chloride conductance in DeltaF508 CF mice by trimethylamine oxide.
American journal of physiology. Lung cellular and molecular physiology 2001;281(1):L52-7.
2000: Beate Illek; Mike E Lizarzaburu; V Lee; Michael H Nantz; Mark J Kurth; Horst Fischer
Structural determinants for activation and block of CFTR-mediated chloride currents by apigenin.
American journal of physiology. Cell physiology 2000;279(6):C1838-46.
1999: Beate Illek; A W Tam; Horst Fischer; Terry E Machen
Anion selectivity of apical membrane conductance of Calu 3 human airway epithelium.
Pflügers Archiv : European journal of physiology 1999;437(6):812-22.
1998: S N Uyekubo; Horst Fischer; Arvydas Maminishkis; Beate Illek; Sheldon Miller; Jonathan H Widdicombe
cAMP-dependent absorption of chloride across airway epithelium.
The American journal of physiology 1998;275(6 Pt 1):L1219-27.
1998: Beate Illek; Horst Fischer; Terry E Machen
Genetic disorders of membrane transport. II. Regulation of CFTR by small molecules including HCO3-.
The American journal of physiology 1998;275(6 Pt 1):G1221-6.
1998: Horst Fischer; Beate Illek; Terry E Machen
Regulation of CFTR by protein phosphatase 2B and protein kinase C.
Pflügers Archiv : European journal of physiology 1998;436(2):175-81.
1996: Beate Illek; Horst Fischer; Terry E Machen
Alternate stimulation of apical CFTR by genistein in epithelia.
The American journal of physiology 1996;270(1 Pt 1):C265-75.
1995: Beate Illek; Horst Fischer; G F Santos; Jonathan H Widdicombe; Terry E Machen; W W Reenstra
cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein.
The American journal of physiology 1995;268(4 Pt 1):C886-93.
1994: J H Poulsen; Horst Fischer; Beate Illek; Terry E Machen
Bicarbonate conductance and pH regulatory capability of cystic fibrosis transmembrane conductance regulator.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5340-4.
1992: Beate Illek; Horst Fischer; Terry E Machen
Intracellular Ca2+ signalling is modulated by K+ channel blockers in colonic epithelial cells (HT-29/B6).
Pflügers Archiv : European journal of physiology 1992;422(1):48-54.
1992: Horst Fischer; Beate Illek; P A Negulescu; Wolfgang Clauss; Terry E Machen
Carbachol-activated calcium entry into HT-29 cells is regulated by both membrane potential and cell volume.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1438-42.