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Aron Fisher

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Intae Lee; Clementina Mesaros; John Zagorski; Mahendra Jain; Ian A Blair; Shampa Chatterjee; Chandra Dodia; Sheldon I Feinstein; Aron B Fisher
A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lung.
Saikumari Y Krishnaiah; Chandra Dodia; Sheldon I Feinstein; Aron B Fisher
p67phox terminates the phospholipase A2-derived signal for activation of NADPH oxidase (NOX2).
Suiping Zhou; Kris DeBolt; Sheldon I Feinstein; Yu-Chin Lien; Tea Shuvaeva; Aron B Fisher
Functional interaction of glutathione S-transferase pi and peroxiredoxin 6 in intact cells.

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2013: Intae Lee; Clementina Mesaros; John Zagorski; Mahendra Jain; Ian A Blair; Shampa Chatterjee; Chandra Dodia; Sheldon I Feinstein; Aron B Fisher
A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lung.
The Journal of pharmacology and experimental therapeutics 2013;345(2):284-96.
2013: Saikumari Y Krishnaiah; Chandra Dodia; Sheldon I Feinstein; Aron B Fisher
p67phox terminates the phospholipase A2-derived signal for activation of NADPH oxidase (NOX2).
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013;27(5):2066-73.
2013: Suiping Zhou; Kris DeBolt; Sheldon I Feinstein; Yu-Chin Lien; Tea Shuvaeva; Aron B Fisher
Functional interaction of glutathione S-transferase pi and peroxiredoxin 6 in intact cells.
The international journal of biochemistry & cell biology 2013;45(2):401-7.
2012: Hamidur Rahaman; David Speicher; Suiping Zhou; Chandra Dodia; Sheldon I Feinstein; Shaohui Huang; Aron B Fisher
Increased phospholipase A2 activity with phosphorylation of peroxiredoxin 6 requires a conformational change in the protein.
Biochemistry 2012;51(27):5521-30.
2012: Yu-Chin Lien; Chandra Dodia; Sheldon I Feinstein; Aron B Fisher
The roles of peroxidase and phospholipase A2 activities of peroxiredoxin 6 in protecting pulmonary microvascular endothelial cells against peroxidative stress.
Antioxidants & redox signaling 2012;16(5):440-51.
2012: Elizabeth A Browning; Shampa Chatterjee; Aron B Fisher
Stop the flow: a paradigm for cell signaling mediated by reactive oxygen species in the pulmonary endothelium.
Annual review of physiology 2012;74():403-24.
2011: Linghui Zhang; Kyle W Robert; Jian-Qin Tao; Kevin Yu; Kris DeBolt; Aron B Fisher; Mitsunori Fukuda; Nankang Hong; Shaohui Huang
Rab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2011;301(4):L461-77.
2011: Aron B Fisher
Peroxiredoxin 6: a bifunctional enzyme with glutathione peroxidase and phospholipase A₂ activities.
Antioxidants & redox signaling 2011;15(3):831-44.
2011: Elena M Sorokina; Sheldon I Feinstein; Suiping Zhou; Aron B Fisher
Intracellular targeting of peroxiredoxin 6 to lysosomal organelles requires MAPK activity and binding to 14-3-3ε.
American journal of physiology. Cell physiology 2011;300(6):C1430-41.
2011: Shampa Chatterjee; Sheldon I Feinstein; Chandra Dodia; Elena Sorokina; Yu-Chin Lien; Su Nguyen; Kris DeBolt; David W Speicher; Aron B Fisher
Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages.
The Journal of biological chemistry 2011;286(13):11696-706.
2011: Melanie Rushefski; Steven M Albelda; Richard Aplenc; Scarlett Bellamy; Sheldon I Feinstein; Rui Feng; Aron B Fisher; Robert Gallop; Paul N Lanken; Mingyao Li; A Russell Localio; Nuala Meyer; Jason D Christie
Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major trauma.
BMC medical genetics 2011;12():77.
2010: Altaf S Kazi; Jian-Qin Tao; Sheldon I Feinstein; Li Zhang; Aron B Fisher; Sandra R Bates
Role of the PI3-kinase signaling pathway in trafficking of the surfactant protein A receptor P63 (CKAP4) on type II pneumocytes.
American journal of physiology. Lung cellular and molecular physiology 2010;299(6):L794-807.
2010: Geng Liu; Sheldon I Feinstein; Yan Wang; Chandra Dodia; Donald Fisher; Kevin Yu; Ye-Shih Ho; Aron B Fisher
Comparison of glutathione peroxidase 1 and peroxiredoxin 6 in protection against oxidative stress in the mouse lung.
Free radical biology & medicine 2010;49(7):1172-81.
2010: Isaac Kirubakaran Sundar; Sangwoon Chung; Jae-Woong Hwang; Gnanapragasam Arunachalam; Suzanne Cook; Hongwei Yao; Witold Mazur; Vuokko L Kinnula; Aron B Fisher; Irfan Rahman
Peroxiredoxin 6 differentially regulates acute and chronic cigarette smoke–mediated lung inflammatory response and injury.
Experimental lung research 2010;36(8):451-62.
2010: Aron B Fisher; Chandra Dodia; Peter Ruckert; Jian-Qin Tao; Sandra R Bates
Pathway to lamellar bodies for surfactant protein A.
American journal of physiology. Lung cellular and molecular physiology 2010;299(1):L51-8.
2009: Elena M Sorokina; Sheldon I Feinstein; Tatyana N Milovanova; Aron B Fisher
Identification of the amino acid sequence that targets peroxiredoxin 6 to lysosome-like structures of lung epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2009;297(5):L871-80.
2009: Bi-Sen Ding; Nankang Hong; Melpo Christofidou-Solomidou; Claudia Gottstein; Steven M Albelda; Douglas B Cines; Aron B Fisher; Vladimir R Muzykantov
Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.
American journal of respiratory and critical care medicine 2009;180(3):247-56.
2009: James R Roede; David J Orlicky; Aron B Fisher; Dennis R Petersen
Overexpression of peroxiredoxin 6 does not prevent ethanol-mediated oxidative stress and may play a role in hepatic lipid accumulation.
The Journal of pharmacology and experimental therapeutics 2009;330(1):79-88.
2009: Aron B Fisher
Redox signaling across cell membranes.
Antioxidants & redox signaling 2009;11(6):1349-56.
2009: Yefim Manevich; Tea Shuvaeva; Chandra Dodia; Altaf S Kazi; Sheldon I Feinstein; Aron B Fisher
Binding of peroxiredoxin 6 to substrate determines differential phospholipid hydroperoxide peroxidase and phospholipase A(2) activities.
Archives of biochemistry and biophysics 2009;485(2):139-49.
2009: Yongzheng Wu; Sheldon I Feinstein; Yefim Manevich; Ibrul Chowdhury; Jhang Ho Pak; Altaf S Kazi; Chandra Dodia; David W Speicher; Aron B Fisher
Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity.
The Biochemical journal 2009;419(3):669-79.
2009: Thorsten Eismann; Nadine Huber; Thomas Shin; Satoshi Kuboki; Elizabeth Galloway; Michael Wyder; Michael J Edwards; Kenneth D Greis; Howard G Shertzer; Aron B Fisher; Alex B Lentsch
Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice.
American journal of physiology. Gastrointestinal and liver physiology 2009;296(2):G266-74.
2009: Ibrul Chowdhury; Yiqun Mo; Ling Gao; Altaf Kazi; Aron B Fisher; Sheldon I Feinstein
Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element.
Free radical biology & medicine 2009;46(2):146-53.
2008: Aron B Fisher; Michael F Beers
Hyperoxia and acute lung injury.
American journal of physiology. Lung cellular and molecular physiology 2008;295(6):L1066; author reply L1067.
2008: Sandra R Bates; Altaf S Kazi; Jian-Qin Tao; Kevin J Yu; Daniel S Gonder; Sheldon I Feinstein; Aron B Fisher
Role of P63 (CKAP4) in binding of surfactant protein-A to type II pneumocytes.
American journal of physiology. Lung cellular and molecular physiology 2008;295(4):L658-69.
2008: Tatyana Milovanova; Shampa Chatterjee; Brian Hawkins; Nankang Hong; Elena M Sorokina; Kris DeBolt; Jonni S Moore; Muniswamy Madesh; Aron B Fisher
Caveolae are an essential component of the pathway for endothelial cell signaling associated with abrupt reduction of shear stress.
Biochimica et biophysica acta 2008;1783(10):1866-75.
2008: Yan Wang; Quan Lu; Guo-liang Teng; Feistein S Sheldon; Micheal F Beers; Aron B Fisher
[Impact of endogenous inflammation caused by adenovirus as a vector in gene therapy: experiment with mice models of acute lung injury].
Zhonghua yi xue za zhi 2008;88(26):1841-5.
2008: Yan Wang; Sheldon I Feinstein; Aron B Fisher
Peroxiredoxin 6 as an antioxidant enzyme: protection of lung alveolar epithelial type II cells from H2O2-induced oxidative stress.
Journal of cellular biochemistry 2008;104(4):1274-85.
2008: Luis A Ralat; Stephanie A Misquitta; Yefim Manevich; Aron B Fisher; Roberta F Colman
Characterization of the complex of glutathione S-transferase pi and 1-cysteine peroxiredoxin.
Archives of biochemistry and biophysics 2008;474(1):109-18.
2008: Qunwei Zhang; Shampa Chatterjee; Zhihua Wei; Wei Dong Liu; Aron B Fisher
Rac and PI3 kinase mediate endothelial cell-reactive oxygen species generation during normoxic lung ischemia.
Antioxidants & redox signaling 2008;10(4):679-89.
2008: Bi-Sen Ding; Nankang Hong; Juan-Carlos Murciano; Kumkum Ganguly; Claudia Gottstein; Melpo Christofidou-Solomidou; Steven M Albelda; Aron B Fisher; Douglas B Cines; Vladimir R Muzykantov
Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature.
Blood 2008;111(4):1999-2006.
2008: Mee-Jung Han; Meenhard Herlyn; Aron B Fisher; David W Speicher
Microscale solution IEF combined with 2-D DIGE substantially enhances analysis depth of complex proteomes such as mammalian cell and tissue extracts.
Electrophoresis 2008;29(3):695-705.
2008: Sandra R Bates; Chandra Dodia; Jian-Qin Tao; Aron B Fisher
Surfactant protein-A plays an important role in lung surfactant clearance: evidence using the surfactant protein-A gene-targeted mouse.
American journal of physiology. Lung cellular and molecular physiology 2008;294(2):L325-33.
2008: Shampa Chatterjee; Kenneth E Chapman; Aron B Fisher
Lung ischemia: a model for endothelial mechanotransduction.
Cell biochemistry and biophysics 2008;52(3):125-38.
2007: Yefim Manevich; Konda S Reddy; Tea Shuvaeva; Sheldon I Feinstein; Aron B Fisher
Structure and phospholipase function of peroxiredoxin 6: identification of the catalytic triad and its role in phospholipid substrate binding.
Journal of lipid research 2007;48(10):2306-18.
2007: NaEun Cheong; Huayan Zhang; Muniswamy Madesh; Ming Zhao; Kevin Yu; Chandra Dodia; Aron B Fisher; Rashmin C Savani; Henry Shuman
ABCA3 is critical for lamellar body biogenesis in vivo.
The Journal of biological chemistry 2007;282(33):23811-7.
2007: Brian Hawkins; Muniswamy Madesh; C J Kirkpatrick; Aron B Fisher
Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling.
Molecular biology of the cell 2007;18(6):2002-12.
2007: Bruno Schremmer; Yefim Manevich; Sheldon I Feinstein; Aron B Fisher
Peroxiredoxins in the lung with emphasis on peroxiredoxin VI.
Sub-cellular biochemistry 2007;44():317-44.
2006: Shampa Chatterjee; I Levitan; Zhihua Wei; Aron B Fisher
KATP channels are an important component of the shear-sensing mechanism in the pulmonary microvasculature.
Microcirculation (New York, N.Y. : 1994) 2006;13(8):633-44.
2006: Norbert Nagy; Gautam Malik; Aron B Fisher; Dipak K Das
Targeted disruption of peroxiredoxin 6 gene renders the heart vulnerable to ischemia-reperfusion injury.
American journal of physiology. Heart and circulatory physiology 2006;291(6):H2636-40.
2006: Nisha Gupta; Yefim Manevich; Altaf S Kazi; Jian-Qin Tao; Aron B Fisher; Sandra R Bates
Identification and characterization of p63 (CKAP4/ERGIC-63/CLIMP-63), a surfactant protein A binding protein, on type II pneumocytes.
American journal of physiology. Lung cellular and molecular physiology 2006;291(3):L436-46.
2006: Aron B Fisher; Chandra Dodia; Kevin Yu; Yefim Manevich; Sheldon I Feinstein
Lung phospholipid metabolism in transgenic mice overexpressing peroxiredoxin 6.
Biochimica et biophysica acta 2006;1761(7):785-92.
2006: Yan Wang; Shelley A Phelan; Yefim Manevich; Sheldon I Feinstein; Aron B Fisher
Transgenic mice overexpressing peroxiredoxin 6 show increased resistance to lung injury in hyperoxia.
American journal of respiratory cell and molecular biology 2006;34(4):481-6.
2006: Yong-Zheng Wu; Yefim Manevich; James L Baldwin; Chandra Dodia; Kevin Yu; Sheldon I Feinstein; Aron B Fisher
Interaction of surfactant protein A with peroxiredoxin 6 regulates phospholipase A2 activity.
The Journal of biological chemistry 2006;281(11):7515-25.
2006: Luis A Ralat; Yefim Manevich; Aron B Fisher; Roberta F Colman
Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes.
Biochemistry 2006;45(2):360-72.
2006: Yan Wang; Sheldon I Feinstein; Yefim Manevich; Ye-Shih Ho; Aron B Fisher
Peroxiredoxin 6 gene-targeted mice show increased lung injury with paraquat-induced oxidative stress.
Antioxidants & redox signaling 2006;8(1-2):229-37.
2006: Tatyana Milovanova; Shampa Chatterjee; Yefim Manevich; Irina Kotelnikova; Kris DeBolt; Muniswamy Madesh; Jonni S Moore; Aron B Fisher
Lung endothelial cell proliferation with decreased shear stress is mediated by reactive oxygen species.
American journal of physiology. Cell physiology 2006;290(1):C66-76.
2005: Qunwei Zhang; Ikuo Matsuzaki; Shampa Chatterjee; Aron B Fisher
Activation of endothelial NADPH oxidase during normoxic lung ischemia is KATP channel dependent.
American journal of physiology. Lung cellular and molecular physiology 2005;289(6):L954-61.
2005: Deepika Jain; Chandra Dodia; Aron B Fisher; Sandra R Bates
Pathways for clearance of surfactant protein A from the lung.
American journal of physiology. Lung cellular and molecular physiology 2005;289(6):L1011-8.
2005: Muniswamy Madesh; Brian Hawkins; Tatyana Milovanova; Cunnigaiper D Bhanumathy; Suresh K Joseph; Satish P RamachandraRao; Kumar Sharma; Tomohiro Kurosaki; Aron B Fisher
Selective role for superoxide in InsP3 receptor-mediated mitochondrial dysfunction and endothelial apoptosis.
The Journal of cell biology 2005;170(7):1079-90.
2005: Yefim Manevich; Aron B Fisher
Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism.
Free radical biology & medicine 2005;38(11):1422-32.
2005: Aron B Fisher; Chandra Dodia; Sheldon I Feinstein; Ye-Shih Ho
Altered lung phospholipid metabolism in mice with targeted deletion of lysosomal-type phospholipase A2.
Journal of lipid research 2005;46(6):1248-56.
2005: Ikuo Matsuzaki; Shampa Chatterjee; Kris DeBolt; Yefim Manevich; Qunwei Zhang; Aron B Fisher
Membrane depolarization and NADPH oxidase activation in aortic endothelium during ischemia reflect altered mechanotransduction.
American journal of physiology. Heart and circulatory physiology 2005;288(1):H336-43.
2004: Yan Wang; Sheldon I Feinstein; Yefim Manevich; Ye-Shih Ho; Aron B Fisher
Lung injury and mortality with hyperoxia are increased in peroxiredoxin 6 gene-targeted mice.
Free radical biology & medicine 2004;37(11):1736-43.
2004: Shampa Chatterjee; Aron B Fisher
ROS to the rescue.
American journal of physiology. Lung cellular and molecular physiology 2004;287(4):L704-5.
2004: Zhihua Wei; Yefim Manevich; Abu-Bakr Al-Mehdi; Shampa Chatterjee; Aron B Fisher
Ca2+ flux through voltage-gated channels with flow cessation in pulmonary microvascular endothelial cells.
Microcirculation (New York, N.Y. : 1994) 2004;11(6):517-26.
2004: Yan Wang; Yefim Manevich; Sheldon I Feinstein; Aron B Fisher
Adenovirus-mediated transfer of the 1-cys peroxiredoxin gene to mouse lung protects against hyperoxic injury.
American journal of physiology. Lung cellular and molecular physiology 2004;286(6):L1188-93.
2004: Tatyana Milovanova; Yefim Manevich; Alex Haddad; Shampa Chatterjee; Jonni S Moore; Aron B Fisher
Endothelial cell proliferation associated with abrupt reduction in shear stress is dependent on reactive oxygen species.
Antioxidants & redox signaling 2004;6(2):245-58.
2004: Yefim Manevich; Sheldon I Feinstein; Aron B Fisher
Activation of the antioxidant enzyme 1-CYS peroxiredoxin requires glutathionylation mediated by heterodimerization with pi GST.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(11):3780-5.
2003: Yiqun Mo; Sheldon I Feinstein; Yefim Manevich; Qunwei Zhang; Lu Lu; Ye-Shih Ho; Aron B Fisher
1-Cys peroxiredoxin knock-out mice express mRNA but not protein for a highly related intronless gene.
FEBS letters 2003;555(2):192-8.
2003: Sandra R Bates; Jian-Qin Tao; Kathleen L Notarfrancesco; Kris DeBolt; Henry Shuman; Aron B Fisher
Effect of surfactant protein A on granular pneumocyte surfactant secretion in vitro.
American journal of physiology. Lung cellular and molecular physiology 2003;285(5):L1055-65.
2003: Shampa Chatterjee; Abu-Bakr Al-Mehdi; Irena Levitan; Troy Stevens; Aron B Fisher
Shear stress increases expression of a KATP channel in rat and bovine pulmonary vascular endothelial cells.
American journal of physiology. Cell physiology 2003;285(4):C959-67.
2003: Han-Suk Kim; Yefim Manevich; Sheldon I Feinstein; Jhang Ho Pak; Ye-Shih Ho; Aron B Fisher
Induction of 1-cys peroxiredoxin expression by oxidative stress in lung epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2003;285(2):L363-9.
2003: Peter Rückert; Sandra R Bates; Aron B Fisher
Role of clathrin- and actin-dependent endocytotic pathways in lung phospholipid uptake.
American journal of physiology. Lung cellular and molecular physiology 2003;284(6):L981-9.
2003: Deepika Jain; Chandra Dodia; Sandra R Bates; Samuel Hawgood; Francis Poulain; Aron B Fisher
SP-A is necessary for increased clearance of alveolar DPPC with hyperventilation or secretagogues.
American journal of physiology. Lung cellular and molecular physiology 2003;284(5):L759-65.
2003: Idit Matot; Yefim Manevich; Abu-Bakr Al-Mehdi; Chun Song; Aron B Fisher
Fluorescence imaging of lipid peroxidation in isolated rat lungs during nonhypoxic lung ischemia.
Free radical biology & medicine 2003;34(6):785-90.
2003: Jean-François Dierick; Frédéric Wenders; Florence Chainiaux; José Remacle; Aron B Fisher; Olivier Toussaint
Retrovirally mediated overexpression of peroxiredoxin VI increases the survival of WI-38 human diploid fibroblasts exposed to cytotoxic doses of tert-butylhydroperoxide and UVB.
Biogerontology 2003;4(3):125-31.
2003: Aron B Fisher; Abu-Bakr Al-Mehdi; Zhihua Wei; Chun Song; Yefim Manevich
Lung ischemia: endothelial cell signaling by reactive oxygen species. A progress report.
Advances in experimental medicine and biology 2003;510():343-7.
2002: Jhang Ho Pak; Yefim Manevich; Han-Suk Kim; Sheldon I Feinstein; Aron B Fisher
An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells.
The Journal of biological chemistry 2002;277(51):49927-34.
2002: Aron B Fisher
Chairman's Summary: Oxidants and antioxidants: Transatlantic Airway Conference 2002.
American journal of respiratory and critical care medicine 2002;166(12 Pt 2):S2-3.
2002: Yefim Manevich; Tom Sweitzer; Jhang Ho Pak; Sheldon I Feinstein; Vladimir R Muzykantov; Aron B Fisher
1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11599-604.
2002: Patricia K Tithof; Mona Elgayyar; Yeesook Cho; Wei Guan; Aron B Fisher; Marc Peters-Golden
Polycyclic aromatic hydrocarbons present in cigarette smoke cause endothelial cell apoptosis by a phospholipase A2-dependent mechanism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(11):1463-4.
2002: Han-Suk Kim; Jhang Ho Pak; Linda W Gonzales; Sheldon I Feinstein; Aron B Fisher
Regulation of 1-cys peroxiredoxin expression in lung epithelial cells.
American journal of respiratory cell and molecular biology 2002;27(2):227-33.
2002: Surafel Mulugeta; Joseph M Gray; Kathleen L Notarfrancesco; Linda W Gonzales; Michael Koval; Sheldon I Feinstein; Philip L Ballard; Aron B Fisher; Henry Shuman
Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter protein ABCA3.
The Journal of biological chemistry 2002;277(25):22147-55.
2002: Aron B Fisher; Abu-Bakr Al-Mehdi; Yefim Manevich
Shear stress and endothelial cell activation.
Critical care medicine 2002;30(5 Suppl):S192-7.
2002: Juan-Carlos Murciano; David Winslow Harshaw; David G Neschis; Lauren Koniaris; Khalil Bdeir; Sandra Medinilla; Aron B Fisher; Michael A Golden; Douglas B Cines; Marian T Nakada; Vladimir R Muzykantov
Platelets inhibit the lysis of pulmonary microemboli.
American journal of physiology. Lung cellular and molecular physiology 2002;282(3):L529-39.
2002: Sandra R Bates; Linda W Gonzales; Jian-Qin Tao; Peter Rueckert; Philip L Ballard; Aron B Fisher
Recovery of rat type II cell surfactant components during primary cell culture.
American journal of physiology. Lung cellular and molecular physiology 2002;282(2):L267-76.
2001: Z Wei; Abu-Bakr Al-Mehdi; Aron B Fisher
Signaling pathway for nitric oxide generation with simulated ischemia in flow-adapted endothelial cells.
American journal of physiology. Heart and circulatory physiology 2001;281(5):H2226-32.
2001: C Song; Abu-Bakr Al-Mehdi; Aron B Fisher
An immediate endothelial cell signaling response to lung ischemia.
American journal of physiology. Lung cellular and molecular physiology 2001;281(4):L993-1000.
2001: Aron B Fisher; S Chien; A I Barakat; Robert M Nerem
Endothelial cellular response to altered shear stress.
American journal of physiology. Lung cellular and molecular physiology 2001;281(3):L529-33.
2001: Yefim Manevich; Abu-Bakr Al-Mehdi; Vladimir R Muzykantov; Aron B Fisher
Oxidative burst and NO generation as initial response to ischemia in flow-adapted endothelial cells.
American journal of physiology. Heart and circulatory physiology 2001;280(5):H2126-35.
2001: Aron B Fisher; Chandra Dodia
Lysosomal-type PLA2 and turnover of alveolar DPPC.
American journal of physiology. Lung cellular and molecular physiology 2001;280(4):L748-54.
2000: Abu-Bakr Al-Mehdi; C Song; K Tozawa; Aron B Fisher
Ca2+- and phosphatidylinositol 3-kinase-dependent nitric oxide generation in lung endothelial cells in situ with ischemia.
The Journal of biological chemistry 2000;275(51):39807-10.
2000: S Schaller-Bals; Sandra R Bates; Kathleen L Notarfrancesco; Jian-Qin Tao; Aron B Fisher; Henry Shuman
Surface-expressed lamellar body membrane is recycled to lamellar bodies.
American journal of physiology. Lung cellular and molecular physiology 2000;279(4):L631-40.
2000: J W Chen; Chandra Dodia; Sheldon I Feinstein; Mahendra K Jain; Aron B Fisher
1-Cys peroxiredoxin, a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities.
The Journal of biological chemistry 2000;275(37):28421-7.
2000: Sandra R Bates; Jian-Qin Tao; S Schaller; Aron B Fisher; Henry Shuman
Lamellar body membrane turnover is stimulated by secretagogues.
American journal of physiology. Lung cellular and molecular physiology 2000;278(3):L443-52.
2000: Abu-Bakr Al-Mehdi; G Zhao; K Tozawa; Aron B Fisher
Depolarization-associated iron release with abrupt reduction in pulmonary endothelial shear stress in situ.
Antioxidants & redox signaling 2000;2(2):335-45.
1999: Z Wei; K Costa; Abu-Bakr Al-Mehdi; Chandra Dodia; Vladimir R Muzykantov; Aron B Fisher
Simulated ischemia in flow-adapted endothelial cells leads to generation of reactive oxygen species and cell signaling.
Circulation research 1999;85(8):682-9.
1999: Aron B Fisher; Chandra Dodia; Yefim Manevich; J W Chen; Sheldon I Feinstein
Phospholipid hydroperoxides are substrates for non-selenium glutathione peroxidase.
The Journal of biological chemistry 1999;274(30):21326-34.
1999: Aron B Fisher; Abu-Bakr Al-Mehdi; Vladimir R Muzykantov
Activation of endothelial NADPH oxidase as the source of a reactive oxygen species in lung ischemia.
Chest 1999;116(1 Suppl):25S-26S.
1999: Vladimir R Muzykantov; Melpo Christofidou-Solomidou; Irina V Balyasnikova; David Winslow Harshaw; L Schultz; Aron B Fisher; Steven M Albelda
Streptavidin facilitates internalization and pulmonary targeting of an anti-endothelial cell antibody (platelet-endothelial cell adhesion molecule 1): a strategy for vascular immunotargeting of drugs.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2379-84.
1999: K Tozawa; Abu-Bakr Al-Mehdi; Vladimir R Muzykantov; Aron B Fisher
In situ imaging of intracellular calcium with ischemia in lung subpleural microvascular endothelial cells.
Antioxidants & redox signaling 1999;1(2):145-54.
1998: Abu-Bakr Al-Mehdi; G Zhao; Chandra Dodia; K Tozawa; K Costa; Vladimir R Muzykantov; C Ross; F Blecha; M Dinauer; Aron B Fisher
Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+.
Circulation research 1998;83(7):730-7.
1998: Elena N Atochina; Irina V Balyasnikova; Sergei M Danilov; D Neil Granger; Aron B Fisher; Vladimir R Muzykantov
Immunotargeting of catalase to ACE or ICAM-1 protects perfused rat lungs against oxidative stress.
The American journal of physiology 1998;275(4 Pt 1):L806-17.
1998: Yolanda Cajal; Chandra Dodia; Aron B Fisher; Mahendra K Jain
Calcium-triggered selective intermembrane exchange of phospholipids by the lung surfactant protein SP-A.
Biochemistry 1998;37(35):12178-88.
1998: Irina V Balyasnikova; Sergei M Danilov; Vladimir R Muzykantov; Aron B Fisher
Modulation of angiotensin-converting enzyme in cultured human vascular endothelial cells.
In vitro cellular & developmental biology. Animal 1998;34(7):545-54.
1998: K Zen; Kathleen L Notarfrancesco; Viola Oorschot; Jan W Slot; Aron B Fisher; Henry Shuman
Generation and characterization of monoclonal antibodies to alveolar type II cell lamellar body membrane.
The American journal of physiology 1998;275(1 Pt 1):L172-83.
1998: Q Chen; Aron B Fisher; D S Strayer; Sandra R Bates
Mechanism for secretagogue-induced surfactant protein A binding to lung epithelial cells.
The American journal of physiology 1998;275(1 Pt 1):L38-46.
1998: S Akiba; Chandra Dodia; X Chen; Aron B Fisher
Characterization of acidic Ca(2+)-independent phospholipase A2 of bovine lung.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1998;120(2):393-404.
1998: T S Kim; Chandra Dodia; X Chen; B B Hennigan; M Jain; Sheldon I Feinstein; Aron B Fisher
Cloning and expression of rat lung acidic Ca(2+)-independent PLA2 and its organ distribution.
The American journal of physiology 1998;274(5 Pt 1):L750-61.
1998: Abu-Bakr Al-Mehdi; G Zhao; Aron B Fisher
ATP-independent membrane depolarization with ischemia in the oxygen-ventilated isolated rat lung.
American journal of respiratory cell and molecular biology 1998;18(5):653-61.
1997: G Zhao; Abu-Bakr Al-Mehdi; Aron B Fisher
Anoxia-reoxygenation versus ischemia in isolated rat lungs.
The American journal of physiology 1997;273(6 Pt 1):L1112-7.
1997: Sandra R Bates; J Xu; Chandra Dodia; Aron B Fisher
Macrophages primed by overnight culture demonstrate a marked stimulation of surfactant protein A degradation.
The American journal of physiology 1997;273(4 Pt 1):L831-9.
1997: Elena N Atochina; Vladimir R Muzykantov; Abu-Bakr Al-Mehdi; Sergei M Danilov; Aron B Fisher
Normoxic lung ischemia/reperfusion accelerates shedding of angiotensin converting enzyme from the pulmonary endothelium.
American journal of respiratory and critical care medicine 1997;156(4 Pt 1):1114-9.
1997: Aron B Fisher; Sheldon I Feinstein; T S Kim; Chandra Dodia; William R Skach
Identification of a cDNA for Ca++-independent phospholipase A2 of lung lamellar bodies/lysosomes.
Chest 1997;111(6 Suppl):88S-89S.
1997: G Zhao; Iraimoudi S Ayene; Aron B Fisher
Role of iron in ischemia-reperfusion oxidative injury of rat lungs.
American journal of respiratory cell and molecular biology 1997;16(3):293-9.
1997: Abu-Bakr Al-Mehdi; Henry Shuman; Aron B Fisher
Intracellular generation of reactive oxygen species during nonhypoxic lung ischemia.
The American journal of physiology 1997;272(2 Pt 1):L294-300.
1997: Aron B Fisher; Chandra Dodia
Role of acidic Ca2+-independent phospholipase A2 in synthesis of lung dipalmitoyl phosphatidylcholine.
The American journal of physiology 1997;272(2 Pt 1):L238-43.
1997: T S Kim; C S Sundaresh; Sheldon I Feinstein; Chandra Dodia; William R Skach; Mahendra K Jain; T Nagase; N Seki; K Ishikawa; N Nomura; Aron B Fisher
Identification of a human cDNA clone for lysosomal type Ca2+-independent phospholipase A2 and properties of the expressed protein.
The Journal of biological chemistry 1997;272(4):2542-50.
1997: Abu-Bakr Al-Mehdi; Henry Shuman; Aron B Fisher
Oxidant generation with K(+)-induced depolarization in the isolated perfused lung.
Free radical biology & medicine 1997;23(1):47-56.
1996: Vladimir R Muzykantov; Elliot S Barnathan; Elena N Atochina; Alice Kuo; Sergei M Danilov; Aron B Fisher
Targeting of antibody-conjugated plasminogen activators to the pulmonary vasculature.
The Journal of pharmacology and experimental therapeutics 1996;279(2):1026-34.
1996: Q Chen; Sandra R Bates; Aron B Fisher
Secretagogues increase the expression of surfactant protein A receptors on lung type II cells.
The Journal of biological chemistry 1996;271(41):25277-83.
1996: Sandra R Bates; Aron B Fisher
Surfactant protein A is degraded by alveolar macrophages.
The American journal of physiology 1996;271(2 Pt 1):L258-66.
1996: Vladimir R Muzykantov; Elena N Atochina; H Ischiropoulos; Sergei M Danilov; Aron B Fisher
Immunotargeting of antioxidant enzyme to the pulmonary endothelium.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5213-8.
1996: Vladimir R Muzykantov; Elena N Atochina; Alice Kuo; Elliot S Barnathan; K Notarfrancesco; Henry Shuman; Chandra Dodia; Aron B Fisher
Endothelial cells internalize monoclonal antibody to angiotensin-converting enzyme.
The American journal of physiology 1996;270(5 Pt 1):L704-13.
1996: Aron B Fisher; Chandra Dodia
Role of phospholipase A2 enzymes in degradation of dipalmitoylphosphatidylcholine by granular pneumocytes.
Journal of lipid research 1996;37(5):1057-64.
1996: Lin Liu; M Wang; Aron B Fisher; Un-Jin Zimmerman
Involvement of annexin II in exocytosis of lamellar bodies from alveolar epithelial type II cells.
The American journal of physiology 1996;270(4 Pt 1):L668-76.
1996: Abu-Bakr Al-Mehdi; Harry Ischiropoulos; Aron B Fisher
Endothelial cell oxidant generation during K(+)-induced membrane depolarization.
Journal of cellular physiology 1996;166(2):274-80.
1995: Lin Liu; Aron B Fisher; Un-Jin Zimmerman
Lung annexin II promotes fusion of isolated lamellar bodies with liposomes.
Biochimica et biophysica acta 1995;1259(2):166-72.
1995: C I Smith; E Rosenberg; S R Reisher; F Li; P Kefalides; Aron B Fisher; Sheldon I Feinstein
Sequence of rat surfactant protein A gene and functional mapping of its upstream region.
The American journal of physiology 1995;269(5 Pt 1):L603-12.
1995: Harry Ischiropoulos; Abu-Bakr Al-Mehdi; Aron B Fisher
Reactive species in ischemic rat lung injury: contribution of peroxynitrite.
The American journal of physiology 1995;269(2 Pt 1):L158-64.
1995: W J Muller; K Zen; Aron B Fisher; Henry Shuman
Pathways for uptake of fluorescently labeled liposomes by alveolar type II cells in culture.
The American journal of physiology 1995;269(1 Pt 1):L11-9.
1995: M R Chinoy; Linda W Gonzales; Philip L Ballard; Aron B Fisher; Roderic G Eckenhoff
Elemental composition of lamellar bodies from fetal and adult human lung.
American journal of respiratory cell and molecular biology 1995;13(1):99-108.
1995: Lin Liu; Aron B Fisher; Un-Jin Zimmerman
Regulation of annexin I by proteolysis in rat alveolar epithelial type II cells.
Biochemistry and molecular biology international 1995;36(2):373-81.
1995: Vladimir R Muzykantov; V D Gavriluk; A Reinecke; Elena N Atochina; Alice Kuo; Elliot S Barnathan; Aron B Fisher
The functional effects of biotinylation of anti-angiotensin-converting enzyme monoclonal antibody in terms of targeting in vivo.
Analytical biochemistry 1995;226(2):279-87.
1995: Stephen R Thom; R L Taber; I I Mendiguren; James M Clark; K R Hardy; Aron B Fisher
Delayed neuropsychologic sequelae after carbon monoxide poisoning: prevention by treatment with hyperbaric oxygen.
Annals of emergency medicine 1995;25(4):474-80.
1995: Un-Jin Zimmerman; B B Hennigan; Lin Liu; C H Campbell; Aron B Fisher
Annexins I, II and III are specific choline binding proteins.
Biochemistry and molecular biology international 1995;35(2):307-15.
1994: Sandra R Bates; Chandra Dodia; Aron B Fisher
Surfactant protein A regulates uptake of pulmonary surfactant by lung type II cells on microporous membranes.
The American journal of physiology 1994;267(6 Pt 1):L753-60.
1994: R Wang; Chandra Dodia; M K Jain; Aron B Fisher
Purification and characterization of a calcium-independent acidic phospholipase A2 from rat lung.
The Biochemical journal 1994;304 ( Pt 1)():131-7.
1994: A Kleinzeller; Chandra Dodia; Avinash Chander; Aron B Fisher
Na(+)-dependent and Na(+)-independent systems of choline transport by plasma membrane vesicles of A549 cell line.
The American journal of physiology 1994;267(5 Pt 1):C1279-87.
1994: Aron B Fisher; Chandra Dodia; Avinash Chander
Inhibition of lung calcium-independent phospholipase A2 by surfactant protein A.
The American journal of physiology 1994;267(3 Pt 1):L335-41.
1994: Michael F Beers; C Y Kim; Chandra Dodia; Aron B Fisher
Localization, synthesis, and processing of surfactant protein SP-C in rat lung analyzed by epitope-specific antipeptide antibodies.
The Journal of biological chemistry 1994;269(32):20318-28.
1994: Harry Ischiropoulos; I Mendiguren; Donald Fisher; Aron B Fisher; Stephen R Thom
Role of neutrophils and nitric oxide in lung alveolar injury from smoke inhalation.
American journal of respiratory and critical care medicine 1994;150(2):337-41.
1994: Michael F Beers; C Y Kim; Chandra Dodia; Aron B Fisher
Synthesis of type II cell lamellar body lysozyme-15 kD protein (lbl-15) by perfused rat lung.
American journal of respiratory cell and molecular biology 1994;11(2):240-8.
1994: Vladimir R Muzykantov; Elena N Atochina; V Gavriljuk; Sergei M Danilov; Aron B Fisher
Immunotargeting of streptavidin to the pulmonary endothelium.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(8):1358-65.
1994: Aron B Fisher; Chandra Dodia; Iraimoudi S Ayene; Abu-Bakr Al-Mehdi
Ischemia-reperfusion injury to the lung.
Annals of the New York Academy of Sciences 1994;723():197-207.
1994: M R Chinoy; Aron B Fisher; Henry Shuman
Confocal imaging of time-dependent internalization and localization of NBD-PC in intact rat lungs.
The American journal of physiology 1994;266(6 Pt 1):L713-21.
1994: Abu-Bakr Al-Mehdi; H Shuman; Aron B Fisher
Fluorescence microtopography of oxidative stress in lung ischemia-reperfusion.
Laboratory investigation; a journal of technical methods and pathology 1994;70(4):579-87.
1994: Aron B Fisher; Chandra Dodia; Avinash Chander; Michael F Beers; Sandra R Bates
Inhibition of Trimeresurus flavoviridis phospholipase A2 by lung surfactant protein A (SP-A).
Biochimica et biophysica acta 1994;1211(3):256-62.
1994: Stephen R Thom; I Mendiguren; Thomas J Van Winkle; Donald Fisher; Aron B Fisher
Smoke inhalation with a concurrent systemic stress results in lung alveolar injury.
American journal of respiratory and critical care medicine 1994;149(1):220-6.
1993: Sandra R Bates; Aron B Fisher
Degradation of surfactant protein B by alveolar type II cells.
The American journal of physiology 1993;265(5 Pt 1):L448-55.
1993: Iraimoudi S Ayene; Abu-Bakr Al-Mehdi; Aron B Fisher
Inhibition of lung tissue oxidation during ischemia/reperfusion by 2-mercaptopropionylglycine.
Archives of biochemistry and biophysics 1993;303(2):307-12.
1993: A Wali; Michael F Beers; Chandra Dodia; Sheldon I Feinstein; Aron B Fisher
ATP and adenosine 3',5'-cyclic monophosphate stimulate the synthesis of surfactant protein A in rat lung.
The American journal of physiology 1993;264(5 Pt 1):L431-7.
1993: Abu-Bakr Al-Mehdi; Chandra Dodia; M K Jain; Aron B Fisher
A phospholipase A2 inhibitor decreases generation of thiobarbituric acid reactive substance during lung ischemia-reperfusion.
Biochimica et biophysica acta 1993;1167(1):56-62.
1993: M R Chinoy; Chandra Dodia; Aron B Fisher
Increased surfactant internalization by rat type II cells cultured on microporous membranes.
The American journal of physiology 1993;264(3 Pt 1):L300-7.
1992: Aron B Fisher; Chandra Dodia; Avinash Chander; A Kleinzeller
Transport of choline by plasma membrane vesicles from lung-derived epithelial cells.
The American journal of physiology 1992;263(6 Pt 1):C1250-7.
1992: Aron B Fisher; Chandra Dodia; Avinash Chander; M Jain
A competitive inhibitor of phospholipase A2 decreases surfactant phosphatidylcholine degradation by the rat lung.
The Biochemical journal 1992;288 ( Pt 2)():407-11.
1992: Un-Jin Zimmerman; David W Speicher; Aron B Fisher
Secretagogue-induced proteolysis of lung spectrin in alveolar epithelial type II cells.
Biochimica et biophysica acta 1992;1137(2):127-34.
1992: Michael F Beers; A Wali; M F Eckenhoff; Sheldon I Feinstein; J H Fisher; Aron B Fisher
An antibody with specificity for surfactant protein C precursors: identification of pro-SP-C in rat lung.
American journal of respiratory cell and molecular biology 1992;7(4):368-78.
1992: Sandra R Bates; Michael F Beers; Aron B Fisher
Binding and uptake of surfactant protein B by alveolar type II cells.
The American journal of physiology 1992;263(3 Pt 1):L333-41.
1992: Michael F Beers; Aron B Fisher
Surfactant protein C: a review of its unique properties and metabolism.
The American journal of physiology 1992;263(2 Pt 1):L151-60.
1992: Iraimoudi S Ayene; Chandra Dodia; Aron B Fisher
Role of oxygen in oxidation of lipid and protein during ischemia/reperfusion in isolated perfused rat lung.
Archives of biochemistry and biophysics 1992;296(1):183-9.
1992: Michael F Beers; Sandra R Bates; Aron B Fisher
Differential extraction for the rapid purification of bovine surfactant protein B.
The American journal of physiology 1992;262(6 Pt 1):L773-8.
1992: Roderic G Eckenhoff; Chandra Dodia; Z Tan; Aron B Fisher
Oxygen-dependent reperfusion injury in the isolated rat lung.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(4):1454-60.
1992: Chandra Dodia; Aron B Fisher; Avinash Chander; A Kleinzeller
Inhibitors of choline transport in alveolar type II epithelial cells.
American journal of respiratory cell and molecular biology 1992;6(4):426-9.
1991: Aron B Fisher; Chandra Dodia; Avinash Chander
Alveolar uptake of lipid and protein components of surfactant.
The American journal of physiology 1991;261(4 Pt 1):L334-40.
1991: Aron B Fisher; Chandra Dodia; Z T Tan; Iraimoudi S Ayene; Roderic G Eckenhoff
Oxygen-dependent lipid peroxidation during lung ischemia.
The Journal of clinical investigation 1991;88(2):674-9.
1991: Aron B Fisher; I Arad; Chandra Dodia; Avinash Chander; Sheldon I Feinstein
cAMP increases synthesis of surfactant-associated protein A by perfused rat lung.
The American journal of physiology 1991;260(4 Pt 1):L226-33.
1991: Roderic G Eckenhoff; S R Rannels; Aron B Fisher
Secretory granule calcium loss after isolation of rat alveolar type II cells.
The American journal of physiology 1991;260(2 Pt 1):L129-35.
1990: Avinash Chander; Aron B Fisher
Regulation of lung surfactant secretion.
The American journal of physiology 1990;258(6 Pt 1):L241-53.
1989: Aron B Fisher; Avinash Chander; Chandra Dodia; J Reicherter; A Kleinzeller
Choline transport by lung epithelium.
American journal of respiratory cell and molecular biology 1989;1(6):455-62.
1989: Aron B Fisher; Chandra Dodia; Avinash Chander
Secretagogues for lung surfactant increase lung uptake of alveolar phospholipids.
The American journal of physiology 1989;257(4 Pt 1):L248-52.
1989: Sandra R Bates; P B Ibach; Aron B Fisher
Phospholipids co-isolated with rat surfactant protein C account for the apparent protein-enhanced uptake of liposomes into lung granular pneumocytes.
Experimental lung research 1989;15(5):695-708.
1988: Avinash Chander; Aron B Fisher
Choline-phosphate cytidyltransferase activity and phosphatidylcholine synthesis in rat granular pneumocytes are increased with exogenous fatty acids.
Biochimica et biophysica acta 1988;958(3):343-51.
1987: Aron B Fisher; Avinash Chander; J Reicherter
Uptake and degradation of natural surfactant by isolated rat granular pneumocytes.
The American journal of physiology 1987;253(6 Pt 1):C792-6.
1987: Avinash Chander; J Reicherter; Aron B Fisher
Degradation of dipalmitoyl phosphatidylcholine by isolated rat granular pneumocytes and reutilization for surfactant synthesis.
The Journal of clinical investigation 1987;79(4):1133-8.
1986: Avinash Chander; R G Johnson; J Reicherter; Aron B Fisher
Lung lamellar bodies maintain an acidic internal pH.
The Journal of biological chemistry 1986;261(13):6126-31.