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Amanda Fisher
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Research Profile (preview)
Living Beings
Physiology
Anatomy
Chemicals & Drugs
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Network (preview)
41
Merkenschlager, Matthias
13
Cobb, Bradley
10
Brown, Karen
9
Smale, Stephen
8
Azuara, Véronique
7
Spivakov, Mikhail
7
Sauer, Stephan
6
Jørgensen, Helle
6
Graf, Daniel
5
Dillon, Niall
4
Baxter, Jonathan
4
Ceredig, R
4
O'connor, Eric
3
Webster, Zoe
3
Zamoyska, Rose
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Publications
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Geonetwork of Amanda Fisher (preview)
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All Publications
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2009: Bruno Ludovica; Mazzarella Luca; Hoogenkamp Maarten; Hertweck Arnulf; Cobb Bradley S; Sauer Stephan; Hadjur Suzana; Leleu Marion; Naoe Yoshinori; Telfer Janice C; Bonifer Constanze; Taniuchi Ichiro; Fisher Amanda G; Merkenschlager Matthias
Runx proteins regulate Foxp3 expression.
The Journal of experimental medicine 2009;206(11):2329-37.
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2009: Hadjur Suzana; Williams Luke M; Ryan Natalie K; Cobb Bradley S; Sexton Tom; Fraser Peter; Fisher Amanda G; Merkenschlager Matthias
Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus.
Nature 2009;460(7253):410-3.
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2009: Caparros Marie-Laure; Fisher Amanda G; Merkenschlager Matthias
Chromosomes and expression mechanisms: life on the edge.
Current opinion in genetics & development 2009;19(2):97-8.
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2009: Jørgensen Helle F; Fisher Amanda G
LOCKing in Cellular Potential.
Cell stem cell 2009;4(3):192-4.
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2009: Jørgensen Helle F; Terry Anna; Beretta Chiara; Pereira C Filipe; Leleu Marion; Chen Zhou-Feng; Kelly Claire; Merkenschlager Matthias; Fisher Amanda G
REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells.
Development (Cambridge, England) 2009;136(5):715-21.
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2009: Jørgensen Helle F; Chen Zhou-Feng; Merkenschlager Matthias; Fisher Amanda G
Is REST required for ESC pluripotency?
Nature 2009;457(7233):E4-5; discussion E7.
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2009: Taylor Benjamin; Cobb Bradley S; Bruno Ludovica; Webster Zoe; Fisher Amanda G; Merkenschlager Matthias
A reappraisal of evidence for probabilistic models of allelic exclusion.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):516-21.
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2009: Hadjur Suzana; Bruno Ludovica; Hertweck Arnulf; Cobb Bradley S; Taylor Benjamin; Fisher Amanda G; Merkenschlager Matthias
IL4 blockade of inducible regulatory T cell differentiation: the role of Th2 cells, Gata3 and PU.1.
Immunology letters 2009;122(1):37-43.
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2008: Sauer Stephan; Bruno Ludovica; Hertweck Arnulf; Finlay David; Leleu Marion; Spivakov Mikhail; Knight Zachary A; Cobb Bradley S; Cantrell Doreen; O'Connor Eric; Shokat Kevan M; Fisher Amanda G; Merkenschlager Matthias
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(22):7797-802.
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2008: Parelho Vania; Hadjur Suzana; Spivakov Mikhail; Leleu Marion; Sauer Stephan; Gregson Heather C; Jarmuz Adam; Canzonetta Claudia; Webster Zoe; Nesterova Tatyana; Cobb Bradley S; Yokomori Kyoko; Dillon Niall; Aragon Luis; Fisher Amanda G; Merkenschlager Matthias
Cohesins functionally associate with CTCF on mammalian chromosome arms.
Cell 2008;132(3):422-33.
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2008: Pereira Carlos F; Terranova Rémi; Ryan Natalie K; Santos Joana; Morris Kelly J; Cui Wei; Merkenschlager Matthias; Fisher Amanda G
Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2.
PLoS genetics 2008;4(9):e1000170.
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2007: Stock Julie K; Giadrossi Sara; Casanova Miguel; Brookes Emily; Vidal Miguel; Koseki Haruhiko; Brockdorff Neil; Fisher Amanda G; Pombo Ana
Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells.
Nature cell biology 2007;9(12):1428-35.
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2007: Spivakov Mikhail; Fisher Amanda G
Epigenetic signatures of stem-cell identity.
Nature reviews. Genetics 2007;8(4):263-71.
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2007: Giadrossi Sara; Dvorkina Maria; Fisher Amanda G
Chromatin organization and differentiation in embryonic stem cell models.
Current opinion in genetics & development 2007;17(2):132-8.
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2007: Lande-Diner Laura; Zhang Jianmin; Ben-Porath Ittai; Amariglio Ninette; Keshet Ilana; Hecht Merav; Azuara Veronique; Fisher Amanda G; Rechavi Gideon; Cedar Howard
Role of DNA methylation in stable gene repression.
The Journal of biological chemistry 2007;282(16):12194-200.
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2007: Thompson Elizabeth C; Cobb Bradley S; Sabbattini Pierangela; Meixlsperger Sonja; Parelho Vania; Liberg David; Taylor Benjamin; Dillon Niall; Georgopoulos Katia; Jumaa Hassan; Smale Stephen T; Fisher Amanda G; Merkenschlager Matthias
Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.
Immunity 2007;26(3):335-44.
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2007: Roessler Stephanie; Györy Ildiko; Imhof Sascha; Spivakov Mikhail; Williams Ruth R; Busslinger Meinrad; Fisher Amanda G; Grosschedl Rudolf
Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5.
Molecular and cellular biology 2007;27(2):579-94.
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2007: Jørgensen Helle F; Azuara Véronique; Amoils Shannon; Spivakov Mikhail; Terry Anna; Nesterova Tatyana; Cobb Bradley S; Ramsahoye Bernard; Merkenschlager Matthias; Fisher Amanda G
The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells.
Genome biology 2007;8(8):R169.
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2006: Cobb Bradley S; Hertweck Arnulf; Smith James; O'Connor Eric; Graf Daniel; Cook Terence; Smale Stephen T; Sakaguchi Shimon; Livesey Frederick J; Fisher Amanda G; Merkenschlager Matthias
A role for Dicer in immune regulation.
The Journal of experimental medicine 2006;203(11):2519-27.
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2006: Jørgensen Helle F; Giadrossi Sara; Casanova Miguel; Endoh Mitsuhiro; Koseki Haruhiko; Brockdorff Neil; Fisher Amanda G
Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells.
Cell cycle (Georgetown, Tex.) 2006;5(13):1411-4.
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2006: Terranova Rémi; Pereira Carlos Filipe; Du Roure Camille; Merkenschlager Matthias; Fisher Amanda G
Acquisition and extinction of gene expression programs are separable events in heterokaryon reprogramming.
Journal of cell science 2006;119(Pt 10):2065-72.
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2006: Azuara Véronique; Perry Pascale; Sauer Stephan; Spivakov Mikhail; Jørgensen Helle F; John Rosalind M; Gouti Mina; Casanova Miguel; Warnes Gary; Merkenschlager Matthias; Fisher Amanda G
Chromatin signatures of pluripotent cell lines.
Nature cell biology 2006;8(5):532-8.
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2006: Du Roure Camille; Takács Katalin; Maxwell Patrick H; Roberts Irene; Dazzi Francesco; Cannella Laura; Merkenschlager Matthias; Fisher Amanda G
Correction of severe anaemia using immuno-regulated gene therapy is achieved by restoring the early erythroblast compartment.
British journal of haematology 2006;132(5):608-14.
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2006: Williams Ruth R E; Azuara Véronique; Perry Pascale; Sauer Stephan; Dvorkina Maria; Jørgensen Helle; Roix Jeffery; McQueen Philip; Misteli Tom; Merkenschlager Matthias; Fisher Amanda G
Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus.
Journal of cell science 2006;119(Pt 1):132-40.
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2005: Terranova Rémi; Sauer Stephan; Merkenschlager Matthias; Fisher Amanda G
The reorganisation of constitutive heterochromatin in differentiating muscle requires HDAC activity.
Experimental cell research 2005;310(2):344-56.
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2005: Cobb Bradley S; Nesterova Tatyana B; Thompson Elizabeth; Hertweck Arnulf; O'Connor Eric; Godwin Jonathan; Wilson Christopher B; Brockdorff Neil; Fisher Amanda G; Smale Stephen T; Merkenschlager Matthias
T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer.
The Journal of experimental medicine 2005;201(9):1367-73.
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2004: Perry Pascale; Sauer Stephan; Billon Nathalie; Richardson William D; Spivakov Mikhail; Warnes Gary; Livesey Frederick J; Merkenschlager Matthias; Fisher Amanda G; Azuara Véronique
A dynamic switch in the replication timing of key regulator genes in embryonic stem cells upon neural induction.
Cell cycle (Georgetown, Tex.) 2004;3(12):1645-50.
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2004: Merkenschlager Matthias; Amoils Shannon; Roldan Esther; Rahemtulla Amin; O'connor Eric; Fisher Amanda G; Brown Karen E
Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice.
The Journal of experimental medicine 2004;200(11):1437-44.
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2004: Hewitt Susannah L; High Frances A; Reiner Steven L; Fisher Amanda G; Merkenschlager Matthias
Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation.
European journal of immunology 2004;34(12):3604-13.
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2004: Takács Katalin; Du Roure Camille; Nabarro Stephen; Dillon Niall; McVey John H; Webster Zoe; Macneil Angus; Bartók István; Higgins Christopher; Gray David; Merkenschlager Matthias; Fisher Amanda G
The regulated long-term delivery of therapeutic proteins by using antigen-specific B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(46):16298-303.
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2004: Baxter Jonathan; Sauer Stephan; Peters Antoine; John Rosalind; Williams Ruth; Caparros Marie-Laure; Arney Katharine; Otte Arie; Jenuwein Thomas; Merkenschlager Matthias; Fisher Amanda G
Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes.
The EMBO journal 2004;23(22):4462-72.
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2004: Arney Katharine L; Fisher Amanda G
Epigenetic aspects of differentiation.
Journal of cell science 2004;117(Pt 19):4355-63.
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2004: Su Ruey-Chyi; Brown Karen E; Saaber Sanam; Fisher Amanda G; Merkenschlager Matthias; Smale Stephen T
Dynamic assembly of silent chromatin during thymocyte maturation.
Nature genetics 2004;36(5):502-6.
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2003: Azuara Véronique; Fisher Amanda G
Maintaining transcriptional states through DNA replication.
Cell cycle (Georgetown, Tex.) 2003;2(6):521-4.
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2003: Azuara Véronique; Brown Karen E; Williams Ruth R E; Webb Natasha; Dillon Niall; Festenstein Richard; Buckle Veronica; Merkenschlager Matthias; Fisher Amanda G
Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication.
Nature cell biology 2003;5(7):668-74.
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2002: Fisher Amanda G
Cellular identity and lineage choice.
Nature reviews. Immunology 2002;2(12):977-82.
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2002: Graf Daniel; Nethisinghe Suran; Palmer Donald B; Fisher Amanda G; Merkenschlager Matthias
The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development.
The Journal of experimental medicine 2002;196(2):163-71.
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2002: Baxter Jonathan; Merkenschlager Matthias; Fisher Amanda G
Nuclear organisation and gene expression.
Current opinion in cell biology 2002;14(3):372-6.
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2002: Kosak Steven T; Skok Jane A; Medina Kay L; Riblet Roy; Le Beau Michelle M; Fisher Amanda G; Singh Harinder
Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development.
Science (New York, N.Y.) 2002;296(5565):158-62.
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2002: Fisher Amanda G; Merkenschlager Matthias
Gene silencing, cell fate and nuclear organisation.
Current opinion in genetics & development 2002;12(2):193-7.
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2002: Smale Stephen T; Fisher Amanda G
Chromatin structure and gene regulation in the immune system.
Annual review of immunology 2002;20():427-62.
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2001: Smith K; Seddon B; Purbhoo M A; Zamoyska R; Fisher A G; Merkenschlager M
Sensory adaptation in naive peripheral CD4 T cells.
The Journal of experimental medicine 2001;194(9):1253-61.
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2001: Skok J A; Brown K E; Azuara V; Caparros M L; Baxter J; Takacs K; Dillon N; Gray D; Perry R P; Merkenschlager M; Fisher A G
Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.
Nature immunology 2001;2(9):848-54.
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2001: Graf D; Timmons P M; Hitchins M; Episkopou V; Moore G; Ito T; Fujiyama A; Fisher A G; Merkenschlager M
Evolutionary conservation, developmental expression, and genomic mapping of mammalian Twisted gastrulation.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(7):554-60.
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2001: Brown K E; Amoils S; Horn J M; Buckle V J; Higgs D R; Merkenschlager M; Fisher A G
Expression of alpha- and beta-globin genes occurs within different nuclear domains in haemopoietic cells.
Nature cell biology 2001;3(6):602-6.
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2000: Cobb B S; Morales-Alcelay S; Kleiger G; Brown K E; Fisher A G; Smale S T
Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.
Genes & development 2000;14(17):2146-60.
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2000: Lovatt M; Yang T H; Stauss H J; Fisher A G; Merkenschlager M
Different doses of agonistic ligand drive the maturation of functional CD4 and CD8 T cells from immature precursors.
European journal of immunology 2000;30(2):371-81.
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1999: Merkenschlager M; Power M O; Pircher H; Fisher A G
Intrathymic deletion of MHC class I-restricted cytotoxic T cell precursors by constitutive cross-presentation of exogenous antigen.
European journal of immunology 1999;29(5):1477-86.
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1999: Brown K E; Baxter J; Graf D; Merkenschlager M; Fisher A G
Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division.
Molecular cell 1999;3(2):207-17.
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1999: Ernst P; Hahm K; Cobb B S; Brown K E; Trinh L A; McCarty A S; Merkenschlager M; Klug C A; Fisher A G; Smale S T
Mechanisms of transcriptional regulation in lymphocyte progenitors: insight from an analysis of the terminal transferase promoter.
Cold Spring Harbor symposia on quantitative biology 1999;64():87-97.
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1998: Hahm K; Cobb B S; McCarty A S; Brown K E; Klug C A; Lee R; Akashi K; Weissman I L; Fisher A G; Smale S T
Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin.
Genes & development 1998;12(6):782-96.
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1997: Brown K E; Guest S S; Smale S T; Hahm K; Merkenschlager M; Fisher A G
Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin.
Cell 1997;91(6):845-54.
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1997: Merkenschlager M; Graf D; Lovatt M; Bommhardt U; Zamoyska R; Fisher A G
How many thymocytes audition for selection?
The Journal of experimental medicine 1997;186(7):1149-58.
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1997: Graf D; Fisher A G; Merkenschlager M
Rational primer design greatly improves differential display-PCR (DD-PCR).
Nucleic acids research 1997;25(11):2239-40.
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1995: Fisher A G; Burdet C; Bunce C; Merkenschlager M; Ceredig R
Lymphoproliferative disorders in IL-7 transgenic mice: expansion of immature B cells which retain macrophage potential.
International immunology 1995;7(3):415-23.
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1995: Lombard-Platet S; Fisher A G; Meyer V; Ceredig R
Expression of functional MHC class II molecules by a mouse pro-B cell clone.
Developmental immunology 1995;4(2):85-92.
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1993: Fisher A G; Burdet C; LeMeur M; Haasner D; Gerber P; Ceredig R
Lymphoproliferative disorders in an IL-7 transgenic mouse line.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7 Suppl 2():S66-8.
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1992: Schleussner C; Kuzio S; Schultze N; Burdet C; Fisher A G; Ceredig R
T cell receptor repertoire of gamma delta cells generated from the 14-day embryonic mouse thymus.
Thymus 1992;20(4):195-216.
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1991: Merkenschlager M; Fisher A G
CD45 isoform switching precedes the activation-driven death of human thymocytes by apoptosis.
International immunology 1991;3(1):1-7.
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1991: Larsson L; Timms E; Blight K; Restall D E; Jat P S; Fisher A G
Characterization of murine thymic stromal-cell lines immortalized by temperature-sensitive simian virus 40 large T or adenovirus 5 E1a.
Developmental immunology 1991;1(4):279-93.
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1990: Goff L K; Larsson L; Fisher A G
Expression of high molecular weight isoforms of CD45 by mouse thymic progenitor cells.
European journal of immunology 1990;20(3):665-71.
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1990: Fisher A G; Larsson L; Goff L K; Restall D E; Happerfield L; Merkenschlager M
Human thymocyte development in mouse organ cultures.
International immunology 1990;2(6):571-8.
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1989: Fisher A G; Goff L K; Lightstone L; Marvel J; Mitchison N A; Poirier G; Stauss H; Zamoyska R
Problems in the physiology of class I and class II MHC molecules, and of CD45.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 2():667-74.
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