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Gary Fisher

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Taihao Quan; John J Voorhees; Emily Little; Zhaoping Qin; Hehui Quan; Gary J Fisher
Elevated matrix metalloproteinases and collagen fragmentation in photodamaged human skin: impact of altered extracellular matrix microenvironment on dermal fibroblast function.
Zhaoping Qin; Gary J Fisher; Taihao Quan
Cysteine-rich Protein 61 (CCN1) Domain-specific Stimulation of Matrix Metalloproteinase-1 Expression through αVβ3 Integrin in Human Skin Fibroblasts.
Taihao Quan; Laure Rittie; Yuan Shao; John J Voorhees; Frank Wang; Wei Xia; Jeffrey S Orringer; Gary J Fisher
Enhancing structural support of the dermal microenvironment activates fibroblasts, endothelial cells, and keratinocytes in aged human skin in vivo.

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2013: Taihao Quan; John J Voorhees; Emily Little; Zhaoping Qin; Hehui Quan; Gary J Fisher
Elevated matrix metalloproteinases and collagen fragmentation in photodamaged human skin: impact of altered extracellular matrix microenvironment on dermal fibroblast function.
The Journal of investigative dermatology 2013;133(5):1362-6.
2013: Zhaoping Qin; Gary J Fisher; Taihao Quan
Cysteine-rich Protein 61 (CCN1) Domain-specific Stimulation of Matrix Metalloproteinase-1 Expression through αVβ3 Integrin in Human Skin Fibroblasts.
The Journal of biological chemistry 2013;288(17):12386-94.
2013: Taihao Quan; Laure Rittie; Yuan Shao; John J Voorhees; Frank Wang; Wei Xia; Jeffrey S Orringer; Gary J Fisher
Enhancing structural support of the dermal microenvironment activates fibroblasts, endothelial cells, and keratinocytes in aged human skin in vivo.
The Journal of investigative dermatology 2013;133(3):658-67.
2013: Laure Rittie; Dana L Sachs; John J Voorhees; Jeffrey S Orringer; Gary J Fisher
Eccrine sweat glands are major contributors to reepithelialization of human wounds.
The American journal of pathology 2013;182(1):163-71.
2012: Ming Fang; Gary J Fisher; Elizabeth L Goldstein; Clifford M Les; Bradford G Orr; Edward D Rothman; A Simon Turner; Kathleen B Welch; Mark M Banaszak Holl
Type I collagen D-spacing in fibril bundles of dermis, tendon, and bone: bridging between nano- and micro-level tissue hierarchy.
ACS nano 2012;6(11):9503-14.
2012: Yiru Xu; Jin Zhou; Thomas Carey; Jonathan B McHugh; John J Voorhees; Gary J Fisher
Receptor-type Protein tyrosine phosphatase β regulates met phosphorylation and function in head and neck squamous cell carcinoma.
Neoplasia (New York, N.Y.) 2012;14(11):1015-22.
2012: Jeffrey S Orringer; Dana L Sachs; Yuan Shao; John J Voorhees; Yilei Cui; Craig Hammerberg; Gary J Fisher
Direct quantitative comparison of molecular responses in photodamaged human skin to fractionated and fully ablative carbon dioxide laser resurfacing.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2012;38(10):1668-77.
2012: Taihao Quan; John J Voorhees; Zhaoping Qin; Gary J Fisher
Cysteine-rich protein 61 (CCN1) mediates replicative senescence-associated aberrant collagen homeostasis in human skin fibroblasts.
Journal of cellular biochemistry 2012;113(9):3011-8.
2012: Yiru Xu; Gary J Fisher
Receptor type protein tyrosine phosphatases (RPTPs) - roles in signal transduction and human disease.
Journal of cell communication and signaling 2012;6(3):125-38.
2012: F Wang; W Xia; C Chen; H Chubb; Gary J Fisher; Johann Gudjonsson; C Hammerberg; Yolanda Rosi Helfrich; Andrew Johnston; Sewon Kang; Lisa E Maier; M Riblett; N Smith; John J Voorhees
Etanercept suppresses regenerative hyperplasia in psoriasis by acutely downregulating epidermal expression of interleukin (IL)-19, IL-20 and IL-24.
The British journal of dermatology 2012;167(1):92-102.
2012: Bruce L Riser; Yiru Xu; Durga Attili; Narasimharao Bhagavathula; Gary J Fisher; Kendra Garchow; Feridoon Najmabadi; Patricia Perone; James Varani
Gadolinium-induced fibrosis is counter-regulated by CCN3 in human dermal fibroblasts: a model for potential treatment of nephrogenic systemic fibrosis.
Journal of cell communication and signaling 2012;6(2):97-105.
2012: William R Swindell; Xianying Xing; Andrew Johnston; Liou Sun; Martha L Bulyk; James T Elder; Gary J Fisher; Johann Gudjonsson
Meta-profiles of gene expression during aging: limited similarities between mouse and human and an unexpectedly decreased inflammatory signature.
PloS one 2012;7(3):e33204.
2011: Taihao Quan; Patrick Robichaud; John J Voorhees; Zhaoping Qin; Gary J Fisher
CCN1 contributes to skin connective tissue aging by inducing age-associated secretory phenotype in human skin dermal fibroblasts.
Journal of cell communication and signaling 2011;5(3):201-7.
2011: Taihao Quan; Yuan Shao; John J Voorhees; Yiru Xu; Zhaoping Qin; Gary J Fisher
Retinoids suppress cysteine-rich protein 61 (CCN1), a negative regulator of collagen homeostasis, in skin equivalent cultures and aged human skin in vivo.
Experimental dermatology 2011;20(7):572-6.
2011: Yiru Xu; Wei Xia; Dustin Baker; Jin Zhou; Hyuk C Cha; John J Voorhees; Gary J Fisher
Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function.
The Journal of biological chemistry 2011;286(18):15980-8.
2011: Andrew B Nesterovitch; Zsuzsa Gyorfy; Mark D Hoffman; Ellen C Moore; Nada Elbuluk; Beata Tryniszewska; Tibor A Rauch; Melinda Simon; Sewon Kang; Gary J Fisher; Katalin Mikecz; Michael D Tharp; Tibor T Glant
Alteration in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6/SHP1) may contribute to neutrophilic dermatoses.
The American journal of pathology 2011;178(4):1434-41.
2011: Laure Rittie; Bernard Perbal; John J Castellot; Jeffrey S Orringer; John J Voorhees; Gary J Fisher
Spatial-temporal modulation of CCN proteins during wound healing in human skin in vivo.
Journal of cell communication and signaling 2011;5(1):69-80.
2011: Fabiana T M C Vicentini; Tianyuan He; Yuan Shao; Maria J V Fonseca; Waldiceu A Verri; Gary J Fisher; Yiru Xu
Quercetin inhibits UV irradiation-induced inflammatory cytokine production in primary human keratinocytes by suppressing NF-κB pathway.
Journal of dermatological science 2011;61(3):162-8.
2011: Jeffrey S Orringer; Laure Rittie; Ted Hamilton; Darius J Karimipour; John J Voorhees; Gary J Fisher
Intraepidermal erbium:YAG laser resurfacing: impact on the dermal matrix.
Journal of the American Academy of Dermatology 2011;64(1):119-28.
2010: Yong Li; Ying Liu; Yiru Xu; John J Voorhees; Gary J Fisher
UV irradiation induces Snail expression by AP-1 dependent mechanism in human skin keratinocytes.
Journal of dermatological science 2010;60(2):105-13.
2010: Jeffrey S Orringer; Laure Rittie; D Baker; John J Voorhees; Gary J Fisher
Molecular mechanisms of nonablative fractionated laser resurfacing.
The British journal of dermatology 2010;163(4):757-68.
2010: Taihao Quan; Zhaoping Qin; Yiru Xu; Tianyuan He; Sewon Kang; John J Voorhees; Gary J Fisher
Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts.
The Journal of investigative dermatology 2010;130(6):1697-706.
2010: Taihao Quan; Yuan Shao; Tianyuan He; John J Voorhees; Gary J Fisher
Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin.
The Journal of investigative dermatology 2010;130(2):415-24.
2010: Yiru Xu; Dustin Baker; Taihao Quan; Joseph J Baldassare; John J Voorhees; Gary J Fisher
Receptor type protein tyrosine phosphatase-kappa mediates cross-talk between transforming growth factor-beta and epidermal growth factor receptor signaling pathways in human keratinocytes.
Molecular biology of the cell 2010;21(1):29-35.
2009: Laure Rittie; Stefan Stoll; Sewon Kang; John J Voorhees; Gary J Fisher
Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin.
Aging cell 2009;8(6):738-51.
2009: T T Do; E C Bailey; F Wang; N Smith; W Lee; Gary J Fisher; John J Voorhees; Sewon Kang
Targeted broadband ultraviolet B phototherapy improves disorders characterized by increased dermal matrix.
The British journal of dermatology 2009;161(6):1405-7.
2009: Darius J Karimipour; Laure Rittie; Craig Hammerberg; Victoria K Min; John J Voorhees; Jeffrey S Orringer; Dana L Sachs; Ted Hamilton; Gary J Fisher
Molecular analysis of aggressive microdermabrasion in photoaged skin.
Archives of dermatology 2009;145(10):1114-22.
2009: Taihao Quan; Zhaoping Qin; Wei Xia; Yuan Shao; John J Voorhees; Gary J Fisher
Matrix-degrading metalloproteinases in photoaging.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2009;14(1):20-4.
2009: Narasimharao Bhagavathula; Marissa DaSilva; Muhammad Nadeem Aslam; Michael Dame; Roscoe L Warner; Yiru Xu; Gary J Fisher; Kent J Johnson; Richard D Swartz; James Varani
Regulation of collagen turnover in human skin fibroblasts exposed to a gadolinium-based contrast agent.
Investigative radiology 2009;44(8):433-9.
2009: Frank Wang; Heh Shin R Kwak; Nada Elbuluk; Anya L Kaczmarek; Ted Hamilton; John J Voorhees; Gary J Fisher; Sewon Kang
Retinoic acid 4-hydroxylase inducibility and clinical response to isotretinoin in patients with acne.
Journal of the American Academy of Dermatology 2009;61(2):252-8.
2009: Yiru Xu; Yuan Shao; Jin Zhou; John J Voorhees; Gary J Fisher
Ultraviolet irradiation-induces epidermal growth factor receptor (EGFR) nuclear translocation in human keratinocytes.
Journal of cellular biochemistry 2009;107(5):873-80.
2009: Dana L Sachs; Sewon Kang; Craig Hammerberg; Yolanda Rosi Helfrich; Darius J Karimipour; Jeffrey S Orringer; Timothy M Johnson; Ted A Hamilton; Gary J Fisher; John J Voorhees
Topical fluorouracil for actinic keratoses and photoaging: a clinical and molecular analysis.
Archives of dermatology 2009;145(6):659-66.
2009: Taihao Quan; Sharon Shin; Zhaoping Qin; Gary J Fisher
Expression of CCN family of genes in human skin in vivo and alterations by solar-simulated ultraviolet irradiation.
Journal of cell communication and signaling 2009;3(1):19-23.
2009: Gary J Fisher; Taihao Quan; Trupta Purohit; Yuan Shao; Moon Kyun Cho; Tianyuan He; James Varani; Sewon Kang; John J Voorhees
Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin.
The American journal of pathology 2009;174(1):101-14.
2008: Jeffrey S Orringer; Craig Hammerberg; Ted Hamilton; Timothy M Johnson; Sewon Kang; Dana L Sachs; Gary J Fisher; John J Voorhees
Molecular effects of photodynamic therapy for photoaging.
Archives of dermatology 2008;144(10):1296-302.
2008: Laure Rittie; Sewon Kang; John J Voorhees; Gary J Fisher
Induction of collagen by estradiol: difference between sun-protected and photodamaged human skin in vivo.
Archives of dermatology 2008;144(9):1129-40.
2008: Frank Wang; Luis Garza; Soyun Cho; Reza Kafi; Craig Hammerberg; Taihao Quan; Ted Hamilton; MD Mayes; Voravit Ratanatharathorn; John J Voorhees; Gary J Fisher; Sewon Kang
Effect of increased pigmentation on the antifibrotic response of human skin to UV-A1 phototherapy.
Archives of dermatology 2008;144(7):851-8.
2008: James Varani; Patricia Perone; Roscoe L Warner; Michael Dame; Sewon Kang; Gary J Fisher; John J Voorhees
Vascular tube formation on matrix metalloproteinase-1-damaged collagen.
British journal of cancer 2008;98(10):1646-52.
2008: Gary J Fisher; James Varani; John J Voorhees
Looking older: fibroblast collapse and therapeutic implications.
Archives of dermatology 2008;144(5):666-72.
2007: Anne-Marie Bleau; Nathalie Planque; N Lazar; Diana Zambelli; A Ori; Taihao Quan; Gary J Fisher; K Scotlandi; Bernard Perbal
Antiproliferative activity of CCN3: involvement of the C-terminal module and post-translational regulation.
Journal of cellular biochemistry 2007;101(6):1475-91.
2007: Laure Rittie; Sanjay Kansra; Stefan Stoll; Yong Li; Johann Gudjonsson; Yuan Shao; Lowell E Michael; Gary J Fisher; Timothy M Johnson; James T Elder
Differential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skin.
The American journal of pathology 2007;170(6):2089-99.
2007: Reza Kafi; Heh Shin R Kwak; Wendy E Schumacher; Soyun Cho; Valerie N Hanft; Ted A Hamilton; Anya L King; Jacqueline D Neal; James Varani; Gary J Fisher; John J Voorhees; Sewon Kang
Improvement of naturally aged skin with vitamin A (retinol).
Archives of dermatology 2007;143(5):606-12.
2007: Frank Wang; Luis Garza; Sewon Kang; James Varani; Jeffrey S Orringer; Gary J Fisher; John J Voorhees
In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin.
Archives of dermatology 2007;143(2):155-63.
2006: Yiru Xu; Yuan Shao; John J Voorhees; Gary J Fisher
Oxidative inhibition of receptor-type protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes.
The Journal of biological chemistry 2006;281(37):27389-97.
2006: Yiru Xu; John J Voorhees; Gary J Fisher
Epidermal growth factor receptor is a critical mediator of ultraviolet B irradiation-induced signal transduction in immortalized human keratinocyte HaCaT cells.
The American journal of pathology 2006;169(3):823-30.
2006: Jeffrey S Orringer; Craig Hammerberg; Lori Lowe; Sewon Kang; Timothy M Johnson; Ted Hamilton; John J Voorhees; Gary J Fisher
The effects of laser-mediated hair removal on immunohistochemical staining properties of hair follicles.
Journal of the American Academy of Dermatology 2006;55(3):402-7.
2006: Taihao Quan; Tianyuan He; Yuan Shao; Lin Lin; Sewon Kang; John J Voorhees; Gary J Fisher
Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skin.
The American journal of pathology 2006;169(2):482-90.
2006: James Varani; Michael Dame; Laure Rittie; Suzanne E G Fligiel; Sewon Kang; Gary J Fisher; John J Voorhees
Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation.
The American journal of pathology 2006;168(6):1861-8.
2006: Laure Rittie; James Varani; Sewon Kang; John J Voorhees; Gary J Fisher
Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivo.
The Journal of investigative dermatology 2006;126(4):732-9.
2006: Darius J Karimipour; Sewon Kang; Timothy M Johnson; Jeffrey S Orringer; Ted Hamilton; Craig Hammerberg; John J Voorhees; Gary J Fisher
Microdermabrasion with and without aluminum oxide crystal abrasion: a comparative molecular analysis of dermal remodeling.
Journal of the American Academy of Dermatology 2006;54(3):405-10.
2005: Yiru Xu; Li-Jun Tan; Vladimir Grachtchouk; John J Voorhees; Gary J Fisher
Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function.
The Journal of biological chemistry 2005;280(52):42694-700.
2005: Jeffrey S Orringer; John J Voorhees; Ted Hamilton; Craig Hammerberg; Sewon Kang; Timothy M Johnson; Darius J Karimipour; Gary J Fisher
Dermal matrix remodeling after nonablative laser therapy.
Journal of the American Academy of Dermatology 2005;53(5):775-82.
2005: Soyun Cho; Lori Lowe; Ted A Hamilton; Gary J Fisher; John J Voorhees; Sewon Kang
Long-term treatment of photoaged human skin with topical retinoic acid improves epidermal cell atypia and thickens the collagen band in papillary dermis.
Journal of the American Academy of Dermatology 2005;53(5):769-74.
2005: Sewon Kang; Soyun Cho; Jin Ho Chung; Craig Hammerberg; Gary J Fisher; John J Voorhees
Inflammation and extracellular matrix degradation mediated by activated transcription factors nuclear factor-kappaB and activator protein-1 in inflammatory acne lesions in vivo.
The American journal of pathology 2005;166(6):1691-9.
2005: Narasimharao Bhagavathula; Kamalakar C Nerusu; Gary J Fisher; Gao Liu; Archana B Thakur; Lorraine Gemmell; Shankar Kumar; Zenghai H Xu; Paul R Hinton; Naoya Tsurushita; Nicholas F Landolfi; John J Voorhees; James Varani
Amphiregulin and epidermal hyperplasia: amphiregulin is required to maintain the psoriatic phenotype of human skin grafts on severe combined immunodeficient mice.
The American journal of pathology 2005;166(4):1009-16.
2005: Taihao Quan; Tianyuan He; John J Voorhees; Gary J Fisher
Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts.
The Journal of biological chemistry 2005;280(9):8079-85.
2005: Muhammad Nadeem Aslam; Helene Fligiel; Humaira Lateef; Gary J Fisher; Isaac Ginsburg; James Varani
PADMA 28: a multi-component herbal preparation with retinoid-like dermal activity but without epidermal effects.
The Journal of investigative dermatology 2005;124(3):524-9.
2005: Gary J Fisher
The pathophysiology of photoaging of the skin.
Cutis; cutaneous medicine for the practitioner 2005;75(2 Suppl):5-8; discussion 8-9.
2005: Darius J Karimipour; Sewon Kang; Timothy M Johnson; Jeffrey S Orringer; Ted Hamilton; Craig Hammerberg; John J Voorhees; Gary J Fisher
Microdermabrasion: a molecular analysis following a single treatment.
Journal of the American Academy of Dermatology 2005;52(2):215-23.
2005: Laure Rittie; Gary J Fisher
Isolation and culture of skin fibroblasts.
Methods in molecular medicine 2005;117():83-98.
2005: Sewon Kang; Wilma F Bergfeld; Alice B Gottlieb; Janet Hickman; John Humeniuk; Steven Kempers; Mark Lebwohl; Nicholas Lowe; Amy McMichael; James Milbauer; Tania Phillips; Jerold Powers; David Rodriguez; Ronald Savin; Joel Shavin; Daniel Sherer; Nancy Silvis; Richard Weinstein; Jonathan Weiss; Craig Hammerberg; Gary J Fisher; Marge Nighland; Rachel Grossman; Judit Nyirady
Long-term efficacy and safety of tretinoin emollient cream 0.05% in the treatment of photodamaged facial skin: a two-year, randomized, placebo-controlled trial.
American journal of clinical dermatology 2005;6(4):245-53.
2004: Jeffrey S Orringer; Sewon Kang; Timothy M Johnson; Darius J Karimipour; Ted Hamilton; Craig Hammerberg; John J Voorhees; Gary J Fisher
Tretinoin treatment before carbon-dioxide laser resurfacing: a clinical and biochemical analysis.
Journal of the American Academy of Dermatology 2004;51(6):940-6.
2004: Jeffrey S Orringer; Sewon Kang; Timothy M Johnson; Darius J Karimipour; Ted Hamilton; Craig Hammerberg; John J Voorhees; Gary J Fisher
Connective tissue remodeling induced by carbon dioxide laser resurfacing of photodamaged human skin.
Archives of dermatology 2004;140(11):1326-32.
2004: Reza Kafi; Gary J Fisher; Taihao Quan; Yuan Shao; Rui Wang; John J Voorhees; Sewon Kang
UV-A1 phototherapy improves nephrogenic fibrosing dermopathy.
Archives of dermatology 2004;140(11):1322-4.
2004: Jeffrey S Orringer; Timothy M Johnson; Sewon Kang; Darius J Karimipour; Craig Hammerberg; Ted Hamilton; John J Voorhees; Gary J Fisher
Effect of carbon dioxide laser resurfacing on epidermal p53 immunostaining in photodamaged skin.
Archives of dermatology 2004;140(9):1073-7.
2004: Taihao Quan; Tianyuan He; Sewon Kang; John J Voorhees; Gary J Fisher
Solar ultraviolet irradiation reduces collagen in photoaged human skin by blocking transforming growth factor-beta type II receptor/Smad signaling.
The American journal of pathology 2004;165(3):741-51.
2004: Jeffrey S Orringer; Sewon Kang; Ted Hamilton; Wendy Schumacher; Soyun Cho; Craig Hammerberg; Gary J Fisher; Darius J Karimipour; Timothy M Johnson; John J Voorhees
Treatment of acne vulgaris with a pulsed dye laser: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2004;291(23):2834-9.
2004: James Varani; Lucia Schuger; Michael Dame; Christina Leonard; Suzanne E G Fligiel; Sewon Kang; Gary J Fisher; John J Voorhees
Reduced fibroblast interaction with intact collagen as a mechanism for depressed collagen synthesis in photodamaged skin.
The Journal of investigative dermatology 2004;122(6):1471-9.
2003: Hui Qin Wang; Taihao Quan; Tianyuan He; Thomas F Franke; John J Voorhees; Gary J Fisher
Epidermal growth factor receptor-dependent, NF-kappaB-independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes.
The Journal of biological chemistry 2003;278(46):45737-45.
2003: Meghan Brennan; Humaa Bhatti; Kamalakar C Nerusu; Narasimharao Bhagavathula; Sewon Kang; Gary J Fisher; James Varani; John J Voorhees
Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin.
Photochemistry and photobiology 2003;78(1):43-8.
2003: Suzanne E G Fligiel; James Varani; Subhash C Datta; Sewon Kang; Gary J Fisher; John J Voorhees
Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro.
The Journal of investigative dermatology 2003;120(5):842-8.
2003: Sewon Kang; Jin Ho Chung; Joo-Heung Lee; Gary J Fisher; Yian Sheng Wan; Elizabeth A Duell; John J Voorhees
Topical N-acetyl cysteine and genistein prevent ultraviolet-light-induced signaling that leads to photoaging in human skin in vivo.
The Journal of investigative dermatology 2003;120(5):835-41.
2002: Gary J Fisher; Sewon Kang; James Varani; Zsuzsanna Bata-Csorgo; Yinsheng Wan; Subhash Datta; John J Voorhees
Mechanisms of photoaging and chronological skin aging.
Archives of dermatology 2002;138(11):1462-70.
2002: Gary J Fisher; Sewon Kang
Phototherapy for scleroderma: biologic rationale, results, and promise.
Current opinion in rheumatology 2002;14(6):723-6.
2002: Laure Rittie; Gary J Fisher
UV-light-induced signal cascades and skin aging.
Ageing research reviews 2002;1(4):705-20.
2002: Jin Ho Chung; Jin Young Seo; Mi Kyoung Lee; Hee Chul Eun; Joo-Heung Lee; Sewon Kang; Gary J Fisher; John J Voorhees
Ultraviolet modulation of human macrophage metalloelastase in human skin in vivo.
The Journal of investigative dermatology 2002;119(2):507-12.
2002: Taihao Quan; Tianyuan He; Sewon Kang; John J Voorhees; Gary J Fisher
Ultraviolet irradiation alters transforming growth factor beta/smad pathway in human skin in vivo.
The Journal of investigative dermatology 2002;119(2):499-506.
2002: James Varani; Patricia Perone; Suzanne E G Fligiel; Gary J Fisher; John J Voorhees
Inhibition of type I procollagen production in photodamage: correlation between presence of high molecular weight collagen fragments and reduced procollagen synthesis.
The Journal of investigative dermatology 2002;119(1):122-9.
2002: Mohamed Boudjelal; John J Voorhees; Gary J Fisher
Retinoid signaling is attenuated by proteasome-mediated degradation of retinoid receptors in human keratinocyte HaCaT cells.
Experimental cell research 2002;274(1):130-7.
2002: Taihao Quan; Tianyuan He; Sewon Kang; John J Voorhees; Gary J Fisher
Connective tissue growth factor: expression in human skin in vivo and inhibition by ultraviolet irradiation.
The Journal of investigative dermatology 2002;118(3):402-8.
2001: James Varani; ME Zeigler; Michael Dame; Sewon Kang; Gary J Fisher; John J Voorhees; Stefan Stoll; James T Elder
Heparin-binding epidermal-growth-factor-like growth factor activation of keratinocyte ErbB receptors Mediates epidermal hyperplasia, a prominent side-effect of retinoid therapy.
The Journal of investigative dermatology 2001;117(6):1335-41.
2001: Sewon Kang; Gary J Fisher; John J Voorhees
Photoaging: pathogenesis, prevention, and treatment.
Clinics in geriatric medicine 2001;17(4):643-59, v-vi.
2001: Gary J Fisher; H C Choi; Zsuzsanna Bata-Csorgo; Yuan Shao; Subhash Datta; ZQ Wang; Sewon Kang; John J Voorhees
Ultraviolet irradiation increases matrix metalloproteinase-8 protein in human skin in vivo.
The Journal of investigative dermatology 2001;117(2):219-26.
2001: Taihao Quan; Tianyuan He; John J Voorhees; Gary J Fisher
Ultraviolet irradiation blocks cellular responses to transforming growth factor-beta by down-regulating its type-II receptor and inducing Smad7.
The Journal of biological chemistry 2001;276(28):26349-56.
2001: James Varani; D Spearman; Patricia Perone; Suzanne E G Fligiel; Subhash C Datta; ZQ Wang; Yuan Shao; Sewon Kang; Gary J Fisher; John J Voorhees
Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro.
The American journal of pathology 2001;158(3):931-42.
2001: Yinsheng Wan; A Belt; Z Wang; John J Voorhees; Gary J Fisher
Transmodulation of epidermal growth factor receptor mediates IL-1 beta-induced MMP-1 expression in cultured human keratinocytes.
International journal of molecular medicine 2001;7(3):329-34.
2001: Yian Sheng Wan; Z Q Wang; Y Shao; John J Voorhees; Gary J Fisher
Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGF receptors in human skin in vivo.
International journal of oncology 2001;18(3):461-6.
2001: Yian Sheng Wan; Z Q Wang; John J Voorhees; Gary J Fisher
EGF receptor crosstalks with cytokine receptors leading to the activation of c-Jun kinase in response to UV irradiation in human keratinocytes.
Cellular signalling 2001;13(2):139-44.
2000: Yinsheng Wan; Z Wang; Y Shao; Yiru Xu; John J Voorhees; Gary J Fisher
UV-induced expression of GADD45 is mediated by an oxidant sensitive pathway in cultured human keratinocytes and in human skin in vivo.
International journal of molecular medicine 2000;6(6):683-8.
2000: Gary J Fisher; Subhash Datta; Zhuo Wang; X Y Li; Taihao Quan; Jin Ho Chung; Sewon Kang; John J Voorhees
c-Jun-dependent inhibition of cutaneous procollagen transcription following ultraviolet irradiation is reversed by all-trans retinoic acid.
The Journal of clinical investigation 2000;106(5):663-70.
2000: Jin Ho Chung; Sewon Kang; James Varani; J Lin; Gary J Fisher; John J Voorhees
Decreased extracellular-signal-regulated kinase and increased stress-activated MAP kinase activities in aged human skin in vivo.
The Journal of investigative dermatology 2000;115(2):177-82.
2000: Charles Ellis; James Varani; Gary J Fisher; ME Zeigler; Harrihar A Pershadsingh; Stephen C Benson; Y Chi; theodore kurtz
Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation.
Archives of dermatology 2000;136(5):609-16.
2000: Mohamed Boudjelal; Zhuwen Wang; John J Voorhees; Gary J Fisher
Ubiquitin/proteasome pathway regulates levels of retinoic acid receptor gamma and retinoid X receptor alpha in human keratinocytes.
Cancer research 2000;60(8):2247-52.
2000: James Varani; Roscoe L Warner; Mehrnaz Gharaee-Kermani; Sem H Phan; Sewon Kang; Jin Ho Chung; ZQ Wang; Subhash C Datta; Gary J Fisher; John J Voorhees
Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin.
The Journal of investigative dermatology 2000;114(3):480-6.
1999: Xiao-Yan Li; Mohamed Boudjelal; JH Xiao; ZH Peng; A Asuru; Sewon Kang; Gary J Fisher; John J Voorhees
1,25-Dihydroxyvitamin D3 increases nuclear vitamin D3 receptors by blocking ubiquitin/proteasome-mediated degradation in human skin.
Molecular endocrinology (Baltimore, Md.) 1999;13(10):1686-94.
1999: Taihao Quan; Gary J Fisher
Cloning and characterization of the human protein kinase C-eta promoter.
The Journal of biological chemistry 1999;274(40):28566-74.
1999: Zhuwen Wang; Mohamed Boudjelal; Sewon Kang; John J Voorhees; Gary J Fisher
Ultraviolet irradiation of human skin causes functional vitamin A deficiency, preventable by all-trans retinoic acid pre-treatment.
Nature medicine 1999;5(4):418-22.
1999: Gary J Fisher; H S Talwar; J Lin; John J Voorhees
Molecular mechanisms of photoaging in human skin in vivo and their prevention by all-trans retinoic acid.
Photochemistry and photobiology 1999;69(2):154-7.
1999: P Lin; Joseph J Baldassare; John J Voorhees; Gary J Fisher
Increased activation of Ras in psoriatic lesions.
Skin pharmacology and applied skin physiology 1999;12(1-2):90-7.
1998: W Di; Xiao-Yan Li; Subhash Datta; A Aström; Gary J Fisher; P Chambon; John J Voorhees; JH Xiao
Keratinocyte-specific retinoid regulation of human cellular retinoic acid binding protein-II (hCRABPII) gene promoter requires an evolutionarily conserved DR1 retinoic acid-responsive element.
The Journal of investigative dermatology 1998;111(6):1109-15.
1998: Y Marikar; Z Wang; Elizabeth A Duell; Martin Petkovich; John J Voorhees; Gary J Fisher
Retinoic acid receptors regulate expression of retinoic acid 4-hydroxylase that specifically inactivates all-trans retinoic acid in human keratinocyte HaCaT cells.
The Journal of investigative dermatology 1998;111(3):434-9.
1998: Gary J Fisher; John J Voorhees
Molecular mechanisms of photoaging and its prevention by retinoic acid: ultraviolet irradiation induces MAP kinase signal transduction cascades that induce Ap-1-regulated matrix metalloproteinases that degrade human skin in vivo.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(1):61-8.
1998: James Varani; Gary J Fisher; Sewon Kang; John J Voorhees
Molecular mechanisms of intrinsic skin aging and retinoid-induced repair and reversal.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(1):57-60.
1998: N J Reynolds; John J Voorhees; Gary J Fisher
Cyclosporin A inhibits 12-O-tetradecanoyl-phorbol-13-acetate-induced cutaneous inflammation in severe combined immunodeficient mice that lack functional lymphocytes.
The British journal of dermatology 1998;139(1):16-22.
1998: Gary J Fisher; H S Talwar; J Lin; P Lin; F McPhillips; Zhuo Wang; X Li; Y Wan; Sewon Kang; John J Voorhees
Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo.
The Journal of clinical investigation 1998;101(6):1432-40.
1998: Gary J Fisher; Subhash C Datta; John J Voorhees
Retinoic acid receptor-gamma in human epidermis preferentially traps all-trans retinoic acid as its ligand rather than 9-cis retinoic acid.
The Journal of investigative dermatology 1998;110(3):297-300.
1997: Gary J Fisher; ZQ Wang; Subhash C Datta; James Varani; Sewon Kang; John J Voorhees
Pathophysiology of premature skin aging induced by ultraviolet light.
The New England journal of medicine 1997;337(20):1419-28.
1997: Sewon Kang; Gary J Fisher; John J Voorhees
Photoaging and topical tretinoin: therapy, pathogenesis, and prevention.
Archives of dermatology 1997;133(10):1280-4.
1997: A Kaiser; Hermann Herbst; Gary J Fisher; M Koenigsmann; W E Berdel; Ernst-Otto Riecken; Stefan Rosewicz
Retinoic acid receptor beta regulates growth and differentiation in human pancreatic carcinoma cells.
Gastroenterology 1997;113(3):920-9.
1997: N J Reynolds; Stuart W McCombie; Bandarpalle B Shankar; W R Bishop; Gary J Fisher
SCH 47112, a novel staurosporine derivative, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and epidermal hyperplasia in hairless mouse skin.
Archives of dermatological research 1997;289(9):540-6.
1997: Joseph J Baldassare; P A Henderson; A Tarver; Gary J Fisher
Thrombin activation of human platelets dissociates a complex containing gelsolin and actin from phosphatidylinositide-specific phospholipase Cgamma1.
The Biochemical journal 1997;324 ( Pt 1)():283-7.
1997: J H Choi; T P O'Connor; Sewon Kang; John J Voorhees; Gary J Fisher
Activation of ribosomal protein S6 kinase in psoriatic lesions and cultured human keratinocytes by epidermal growth factor receptor ligands.
The Journal of investigative dermatology 1997;108(1):98-102.
1996: Gary J Fisher; John J Voorhees
Molecular mechanisms of retinoid actions in skin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(9):1002-13.
1996: S B Kurlandsky; Elizabeth A Duell; Sewon Kang; John J Voorhees; Gary J Fisher
Auto-regulation of retinoic acid biosynthesis through regulation of retinol esterification in human keratinocytes.
The Journal of biological chemistry 1996;271(26):15346-52.
1996: Sewon Kang; K J Kim; Christopher E M Griffiths; T Y Wong; H S Talwar; Gary J Fisher; David F Gordon; Ted A Hamilton; Charles Ellis; John J Voorhees
Topical tretinoin (retinoic acid) improves early stretch marks.
Archives of dermatology 1996;132(5):519-26.
1996: Gary J Fisher; Subhash C Datta; H S Talwar; Z Q Wang; James Varani; Sewon Kang; John J Voorhees
Molecular basis of sun-induced premature skin ageing and retinoid antagonism.
Nature 1996;379(6563):335-9.
1995: Sewon Kang; Elizabeth A Duell; Gary J Fisher; Subhash C Datta; Z Q Wang; A P Reddy; A Tavakkol; J Y Yi; Christopher E M Griffiths; James T Elder
Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation.
The Journal of investigative dermatology 1995;105(4):549-56.
1995: N J Reynolds; J Y Yi; Gary J Fisher; Kevin D Cooper; John J Voorhees; Christopher E M Griffiths
Down-regulation of Langerhans cell protein kinase C-beta isoenzyme expression in inflammatory and hyperplastic dermatoses.
The British journal of dermatology 1995;133(2):157-67.
1995: H S Talwar; Christopher E M Griffiths; Gary J Fisher; Ted A Hamilton; John J Voorhees
Reduced type I and type III procollagens in photodamaged adult human skin.
The Journal of investigative dermatology 1995;105(2):285-90.
1995: Gary J Fisher; A P Reddy; Subhash C Datta; Sewon Kang; J Y Yi; P Chambon; John J Voorhees
All-trans retinoic acid induces cellular retinol-binding protein in human skin in vivo.
The Journal of investigative dermatology 1995;105(1):80-6.
1995: AS Paller; S L Arnsmeier; Gary J Fisher; QC Yu
Ganglioside GT1b induces keratinocyte differentiation without activating protein kinase C.
Experimental cell research 1995;217(1):118-24.
1994: S B Kurlandsky; JH Xiao; Elizabeth A Duell; John J Voorhees; Gary J Fisher
Biological activity of all-trans retinol requires metabolic conversion to all-trans retinoic acid and is mediated through activation of nuclear retinoid receptors in human keratinocytes.
The Journal of biological chemistry 1994;269(52):32821-7.
1994: N J Reynolds; Joseph J Baldassare; P A Henderson; J L Shuler; L M Ballas; D J Burns; C R Moomaw; Gary J Fisher
Translocation and downregulation of protein kinase C isoenzymes-alpha and -epsilon by phorbol ester and bryostatin-1 in human keratinocytes and fibroblasts.
The Journal of investigative dermatology 1994;103(3):364-9.
1994: Gary J Fisher; H S Talwar; JH Xiao; Subhash C Datta; A P Reddy; M P Gaub; Cécile Rochette-Egly; P Chambon; John J Voorhees
Immunological identification and functional quantitation of retinoic acid and retinoid X receptor proteins in human skin.
The Journal of biological chemistry 1994;269(32):20629-35.
1993: T Kojima; M A Cromie; Gary J Fisher; John J Voorhees; James T Elder
GRO-alpha mRNA is selectively overexpressed in psoriatic epidermis and is reduced by cyclosporin A in vivo, but not in cultured keratinocytes.
The Journal of investigative dermatology 1993;101(6):767-72.
1993: P Strange; Kevin D Cooper; E R Hansen; Gary J Fisher; J K Larsen; David A Fox; C Krag; John J Voorhees; Ole Baadsgaard
T-lymphocyte clones initiated from lesional psoriatic skin release growth factors that induce keratinocyte proliferation.
The Journal of investigative dermatology 1993;101(5):695-700.
1993: N S Ryder; H S Talwar; N J Reynolds; John J Voorhees; Gary J Fisher
Phosphatidic acid and phospholipase D both stimulate phosphoinositide turnover in cultured human keratinocytes.
Cellular signalling 1993;5(6):787-94.
1993: Gary J Fisher; A Tavakkol; K Leach; D Burns; P Basta; C Loomis; Christopher E M Griffiths; Kevin D Cooper; N J Reynolds; James T Elder
Differential expression of protein kinase C isoenzymes in normal and psoriatic adult human skin: reduced expression of protein kinase C-beta II in psoriasis.
The Journal of investigative dermatology 1993;101(4):553-9.
1993: N J Reynolds; Gary J Fisher; Christopher E M Griffiths; A Tavakkol; H S Talwar; P E Rowse; Ted A Hamilton; John J Voorhees
Retinoic acid metabolites exhibit biological activity in human keratinocytes, mouse melanoma cells and hairless mouse skin in vivo.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1636-42.
1993: N J Reynolds; H S Talwar; Joseph J Baldassare; P A Henderson; James T Elder; John J Voorhees; Gary J Fisher
Differential induction of phosphatidylcholine hydrolysis, diacylglycerol formation and protein kinase C activation by epidermal growth factor and transforming growth factor-alpha in normal human skin fibroblasts and keratinocytes.
The Biochemical journal 1993;294 ( Pt 2)():535-44.
1993: H S Talwar; Christopher E M Griffiths; Gary J Fisher; A Russman; K Krach; S Benrazavi; John J Voorhees
Differential regulation of tyrosinase activity in skin of white and black individuals in vivo by topical retinoic acid.
The Journal of investigative dermatology 1993;100(6):800-5.
1993: Joseph J Baldassare; A P Tarver; P A Henderson; W M Mackin; B Sahagan; Gary J Fisher
Reconstitution of thromboxane A2 receptor-stimulated phosphoinositide hydrolysis in isolated platelet membranes: involvement of phosphoinositide-specific phospholipase C-beta and GTP-binding protein Gq.
The Biochemical journal 1993;291 ( Pt 1)():235-40.
1992: E Y Chang; Craig Hammerberg; Gary J Fisher; Ole Baadsgaard; Charles Ellis; John J Voorhees; Kevin D Cooper
T-cell activation is potentiated by cytokines released by lesional psoriatic, but not normal, epidermis.
Archives of dermatology 1992;128(11):1479-85.
1992: A P Reddy; J Y Chen; T Zacharewski; Hinrich Gronemeyer; John J Voorhees; Gary J Fisher
Characterization and purification of human retinoic acid receptor-gamma 1 overexpressed in the baculovirus-insect cell system.
The Biochemical journal 1992;287 ( Pt 3)():833-40.
1992: Christopher E M Griffiths; Gary J Fisher; L J Finkel; John J Voorhees
Mechanisms of action of retinoic acid in skin repair.
The British journal of dermatology 1992;127 Suppl 41():21-4.
1992: A Tavakkol; James T Elder; Christopher E M Griffiths; Kevin D Cooper; H Talwar; Gary J Fisher; K M Keane; S K Foltin; John J Voorhees
Expression of growth hormone receptor, insulin-like growth factor 1 (IGF-1) and IGF-1 receptor mRNA and proteins in human skin.
The Journal of investigative dermatology 1992;99(3):343-9.
1992: Q Y Zhang; Craig Hammerberg; Joseph J Baldassare; P A Henderson; D Burns; M Ceska; John J Voorhees; Gary J Fisher
Retinoic acid and phorbol ester synergistically up-regulate IL-8 expression and specifically modulate protein kinase C-epsilon in human skin fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(4):1402-8.
1992: Joseph J Baldassare; P A Henderson; D Burns; C Loomis; Gary J Fisher
Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. Correlation with 1,2-diacylglycerol levels.
The Journal of biological chemistry 1992;267(22):15585-90.
1992: Craig Hammerberg; W P Arend; Gary J Fisher; Lawrence S Chan; A E Berger; Stephen J Haskill; John J Voorhees; Kevin D Cooper
Interleukin-1 receptor antagonist in normal and psoriatic epidermis.
The Journal of clinical investigation 1992;90(2):571-83.
1992: S B Klein; Gary J Fisher; T C Jensen; J Mendelsohn; John J Voorhees; James T Elder
Regulation of TGF-alpha expression in human keratinocytes: PKC-dependent and -independent pathways.
Journal of cellular physiology 1992;151(2):326-36.
1992: Kevin D Cooper; Ole Baadsgaard; Elizabeth A Duell; Gary J Fisher; Charles Ellis; John J Voorhees
Langerhans cell sensitivity to in vitro versus in vivo loading with cyclosporine A.
The Journal of investigative dermatology 1992;98(2):259-61.
1992: S E Fligiel; D R Inman; H S Talwar; Gary J Fisher; John J Voorhees; James Varani
Modulation of growth in normal and malignant melanocytic cells by all-trans retinoic acid.
Journal of cutaneous pathology 1992;19(1):27-33.
1992: Gary J Fisher; A Tavakkol; Christopher E M Griffiths; James T Elder; Q Y Zhang; L Finkel; D Danielpour; A B Glick; H Higley; L Ellingsworth
Differential modulation of transforming growth factor-beta 1 expression and mucin deposition by retinoic acid and sodium lauryl sulfate in human skin.
The Journal of investigative dermatology 1992;98(1):102-8.
1992: N I Kim; Kevin D Cooper; Gary J Fisher; Ole Baadsgaard; John J Voorhees; Craig Hammerberg
Psoriatic skin reveals the in vivo presence of an epidermal IL-1 inhibitor.
Archives of dermatological research 1992;284(2):71-6.
1992: James T Elder; Carolyn I Sartor; D K Boman; S Benrazavi; Gary J Fisher; Mark Pittelkow
Interleukin-6 in psoriasis: expression and mitogenicity studies.
Archives of dermatological research 1992;284(6):324-32.
1991: Craig Hammerberg; Gary J Fisher; John J Voorhees; Kevin D Cooper
Elevated thymidine phosphorylase activity in psoriatic lesions accounts for the apparent presence of an epidermal "growth inhibitor," but is not in itself growth inhibitory.
The Journal of investigative dermatology 1991;97(2):286-90.
1991: John C Reed; H S Talwar; M Cuddy; G Baffy; J Williamson; U R Rapp; Gary J Fisher
Mitochondrial protein p26 BCL2 reduces growth factor requirements of NIH3T3 fibroblasts.
Experimental cell research 1991;195(2):277-83.
1991: Elizabeth A Duell; V Fischer; Gary J Fisher; A Astrom; John J Voorhees
Cyclosporine A metabolism by cytochrome P-450III occurs in microsomes from rat liver but not from normal epidermis or psoriatic lesions.
The Journal of investigative dermatology 1991;96(6):827-31.
1991: Gary J Fisher; J Esmann; Christopher E M Griffiths; H S Talwar; Elizabeth A Duell; Craig Hammerberg; James T Elder; L J Finkel; G D Karabin; Brian J Nickoloff
Cellular, immunologic and biochemical characterization of topical retinoic acid-treated human skin.
The Journal of investigative dermatology 1991;96(5):699-707.
1991: James T Elder; Gary J Fisher; Q Y Zhang; D Eisen; A Krust; P Kastner; P Chambon; John J Voorhees
Retinoic acid receptor gene expression in human skin.
The Journal of investigative dermatology 1991;96(4):425-33.
1991: Gary J Fisher; P A Henderson; John J Voorhees; Joseph J Baldassare
Epidermal growth factor-induced hydrolysis of phosphatidylcholine by phospholipase D and phospholipase C in human dermal fibroblasts.
Journal of cellular physiology 1991;146(2):309-17.
1990: Kevin D Cooper; John J Voorhees; Gary J Fisher; Lawrence S Chan; Aditya K Gupta; Ole Baadsgaard
Effects of cyclosporine on immunologic mechanisms in psoriasis.
Journal of the American Academy of Dermatology 1990;23(6 Pt 2):1318-26; discussion 1326-8.
1990: Ole Baadsgaard; Gary J Fisher; John J Voorhees; Kevin D Cooper
Interactions of epidermal cells and T cells in inflammatory skin diseases.
Journal of the American Academy of Dermatology 1990;23(6 Pt 2):1312-6; discussion 1316-7.
1990: H S Talwar; Gary J Fisher; John J Voorhees
Bradykinin induces phosphoinositide turnover, 1,2-diglyceride formation, and growth in cultured adult human keratinocytes.
The Journal of investigative dermatology 1990;95(6):705-10.
1990: Ole Baadsgaard; Gary J Fisher; John J Voorhees; Kevin D Cooper
The role of immune system in the pathogenesis of psoriasis.
The Journal of investigative dermatology 1990;95(5 Suppl):32S-34S.
1990: Kevin D Cooper; Craig Hammerberg; Ole Baadsgaard; James T Elder; Lawrence S Chan; R S Taylor; John J Voorhees; Gary J Fisher
Interleukin-1 in human skin: dysregulation in psoriasis.
The Journal of investigative dermatology 1990;95(5 Suppl):24S-26S.
1990: Gary J Fisher; H S Talwar; A Tavakkol; J Esmann; Joseph J Baldassare; James T Elder; Christopher E M Griffiths; Ole Baadsgaard; Kevin D Cooper; John J Voorhees
Phosphoinositide-mediated signal transduction in normal and psoriatic epidermis.
The Journal of investigative dermatology 1990;95(5 Suppl):15S-17S.
1990: L T Elder; S B Klein; A Tavakkol; Gary J Fisher; Brian J Nickoloff; John J Voorhees
Growth factor and proto-oncogene expression in psoriasis.
The Journal of investigative dermatology 1990;95(5 Suppl):7S-9S.
1990: James T Elder; S B Klein; A Tavakkol; Gary J Fisher; Brian J Nickoloff; John J Voorhees
Growth factor and proto-oncogene expression in psoriasis.
The Journal of investigative dermatology 1990;95(5):7S-9S.
1990: Ole Baadsgaard; Gary J Fisher; John J Voorhees; Kevin D Cooper
The role of the immune system in the pathogenesis of psoriasis.
The Journal of investigative dermatology 1990;95(5):32S-34S.
1990: Kevin D Cooper; Craig Hammerberg; Ole Baadsgaard; James T Elder; Lawrence S Chan; R S Taylor; John J Voorhees; Gary J Fisher
Interleukin-1 in human skin: dysregulation in psoriasis.
The Journal of investigative dermatology 1990;95(5):24S-26S.
1990: Gary J Fisher; H S Talwar; A Tavakkol; J Esmann; Joseph J Baldassare; James T Elder; Christopher E M Griffiths; Ole Baadsgaard; Kevin D Cooper; John J Voorhees
Phosphoinositide-mediated signal transduction in normal and psoriatic epidermis.
The Journal of investigative dermatology 1990;95(5):15S-17S.
1990: Gary J Fisher; H S Talwar; Joseph J Baldassare; P A Henderson; John J Voorhees
Increased phospholipase C-catalyzed hydrolysis of phosphatidylinositol-4,5-bisphosphate and 1,2-sn-diacylglycerol content in psoriatic involved compared to uninvolved and normal epidermis.
The Journal of investigative dermatology 1990;95(4):428-35.
1990: Ole Baadsgaard; P Tong; James T Elder; E R Hansen; V Ho; Craig Hammerberg; G Lange-Vejlsgaard; David A Fox; Gary J Fisher; Lawrence S Chan
UM4D4+ (CDw60) T cells are compartmentalized into psoriatic skin and release lymphokines that induce a keratinocyte phenotype expressed in psoriatic lesions.
The Journal of investigative dermatology 1990;95(3):275-82.
1990: Kevin D Cooper; Craig Hammerberg; Ole Baadsgaard; James T Elder; Lawrence S Chan; D N Sauder; John J Voorhees; Gary J Fisher
IL-1 activity is reduced in psoriatic skin. Decreased IL-1 alpha and increased nonfunctional IL-1 beta.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(12):4593-603.
1990: Christopher E M Griffiths; Gary J Fisher; M W Harding; James T Elder; John J Voorhees
Cyclophilin content of normal and psoriatic epidermis.
The Journal of investigative dermatology 1990;94(4):436-40.
1990: Christopher E M Griffiths; J Esmann; Gary J Fisher; John J Voorhees; Brian J Nickoloff
Differential modulation of keratinocyte intercellular adhesion molecule-I expression by gamma interferon and phorbol ester: evidence for involvement of protein kinase C signal transduction.
The British journal of dermatology 1990;122(3):333-42.
1990: James T Elder; L R Ellingsworth; Gary J Fisher; John J Voorhees
Transforming growth factor-beta in psoriasis. Pathogenesis and therapy.
Annals of the New York Academy of Sciences 1990;593():218-30.
1989: Aditya K Gupta; M D Brown; Charles Ellis; L L Rocher; Gary J Fisher; Ole Baadsgaard; Kevin D Cooper; John J Voorhees
Cyclosporine in dermatology.
Journal of the American Academy of Dermatology 1989;21(6):1245-56.
1989: J Esmann; John J Voorhees; Gary J Fisher
Increased membrane-associated transglutaminase activity in psoriasis.
Biochemical and biophysical research communications 1989;164(1):219-24.
1989: Gary J Fisher; H S Talwar; N S Ryder; John J Voorhees
Differential activation of human skin cells by platelet activating factor: stimulation of phosphoinositide turnover and arachidonic acid mobilization in keratinocytes but not in fibroblasts.
Biochemical and biophysical research communications 1989;163(3):1344-50.
1989: Aditya K Gupta; Gary J Fisher; James T Elder; H S Talwar; J Esmann; Elizabeth A Duell; Brian J Nickoloff; John J Voorhees
Topical cyclosporine A inhibits the phorbol ester induced hyperplastic inflammatory response but not protein kinase C activation in mouse epidermis.
The Journal of investigative dermatology 1989;93(3):379-86.
1989: Brian J Nickoloff; Raj S Mitra; James T Elder; Gary J Fisher; John J Voorhees
Decreased growth inhibition by recombinant gamma interferon is associated with increased transforming growth factor-alpha production in keratinocytes cultured from psoriatic lesions.
The British journal of dermatology 1989;121(2):161-74.
1989: H S Talwar; Gary J Fisher; V A Harris; John J Voorhees
Agonist-induced hydrolysis of phosphoinositides and formation of 1,2-diacylglycerol in adult human keratinocytes.
The Journal of investigative dermatology 1989;93(2):241-5.
1989: Joseph J Baldassare; P A Henderson; Gary J Fisher
Isolation and characterization of one soluble and two membrane-associated forms of phosphoinositide-specific phospholipase C from human platelets.
Biochemistry 1989;28(14):6010-6.
1989: Gary J Fisher; Joseph J Baldassare; John J Voorhees
GTP-dependent hydrolysis of phosphatidylinositol-4,5-bisphosphate by soluble phospholipase C from adult human epidermis.
The Journal of investigative dermatology 1989;92(6):831-6.
1989: M C Pike; C S Lee; James T Elder; John J Voorhees; Gary J Fisher
Increased phosphatidylinositol kinase activity in psoriatic epidermis.
The Journal of investigative dermatology 1989;92(6):791-7.
1989: H Takematsu; Gary J Fisher; John J Voorhees
A novel histone-stimulated protein kinase in normal and psoriatic epidermis.
The Journal of investigative dermatology 1989;92(3):385-90.
1989: James T Elder; Gary J Fisher; P B Lindquist; G L Bennett; Mark Pittelkow; R J Coffey; L Ellingsworth; R Derynck; John J Voorhees
Overexpression of transforming growth factor alpha in psoriatic epidermis.
Science (New York, N.Y.) 1989;243(4892):811-4.
1989: Joseph J Baldassare; P A Henderson; Gary J Fisher
Plasma membrane associated phospholipase C from human platelets: synergistic stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis by thrombin and guanosine 5'-O-(3-thiotriphosphate).
Biochemistry 1989;28(1):56-60.
1989: Knud Kragballe; Gary J Fisher; John J Voorhees
Modulators of cutaneous inflammation and proliferation in psoriasis.
Immunology series 1989;46():403-24.
1988: Aditya K Gupta; Gary J Fisher; James T Elder; Brian J Nickoloff; John J Voorhees
Sphingosine inhibits phorbol ester-induced inflammation, ornithine decarboxylase activity, and activation of protein kinase C in mouse skin.
The Journal of investigative dermatology 1988;91(5):486-91.
1988: Gary J Fisher; Elizabeth A Duell; Brian J Nickoloff; Thomas M Annesley; J K Kowalke; Charles Ellis; John J Voorhees
Levels of cyclosporin in epidermis of treated psoriasis patients differentially inhibit growth of keratinocytes cultured in serum free versus serum containing media.
The Journal of investigative dermatology 1988;91(2):142-6.
1988: Joseph J Baldassare; M A Knipp; P A Henderson; Gary J Fisher
GTP gamma S-stimulated hydrolysis of phosphatidylinositol-4,5-bisphosphate soluble phospholipase C from human platelets requires soluble GTP-binding protein.
Biochemical and biophysical research communications 1988;154(1):351-7.
1988: James T Elder; Aditya K Gupta; Gary J Fisher; John J Voorhees
Cyclosporine inhibits ornithine decarboxylase gene expression and acute inflammation in response to phorbol ester treatment of hairless mouse skin.
Transplantation proceedings 1988;20(3 Suppl 4):95-104.
1988: Brian J Nickoloff; Gary J Fisher; Raj S Mitra; John J Voorhees
Direct cytopathic effects of cyclosporine A on rapidly proliferating cultured keratinocytes and dermal fibroblasts.
Transplantation proceedings 1988;20(3 Suppl 4):85-90.
1988: M D Brown; Aditya K Gupta; Charles Ellis; K D Cooper; Gary J Fisher; John J Voorhees
Cyclosporine for the treatment of psoriasis.
Transplantation proceedings 1988;20(3 Suppl 4):26-31.
1988: Brian J Nickoloff; Gary J Fisher; Raj S Mitra; John J Voorhees
Additive and synergistic antiproliferative effects of cyclosporin A and gamma interferon on cultured human keratinocytes.
The American journal of pathology 1988;131(1):12-8.
1987: Gary J Fisher; V A Harris; John J Voorhees
Purification and characterization of calcium/phospholipid-dependent kinase from adult human epidermis.
The Journal of investigative dermatology 1987;89(5):484-8.
1987: F Horn; F Marks; Gary J Fisher; Cynthia L Marcelo; John J Voorhees
Decreased protein kinase C activity in psoriatic versus normal epidermis.
The Journal of investigative dermatology 1987;88(2):220-2.
1987: Gary J Fisher; F Horn; F Marks; John J Voorhees
Protein kinase C in normal and psoriatic adult human epidermis.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17B():643-6.
1987: Gary J Fisher; L K Kelley; C H Smith
ATP-dependent calcium transport across basal plasma membranes of human placental trophoblast.
The American journal of physiology 1987;252(1 Pt 1):C38-46.
1986: J J Baldassare; Gary J Fisher
Regulation of membrane-associated and cytosolic phospholipase C activities in human platelets by guanosine triphosphate.
The Journal of biological chemistry 1986;261(26):11942-4.
1986: J J Baldassare; Gary J Fisher
GTP and cytosol stimulate phosphoinositide hydrolysis in isolated platelet membranes.
Biochemical and biophysical research communications 1986;137(2):801-5.
1985: Joseph J Baldassare; S Bakshian; M A Knipp; Gary J Fisher
Inhibition of fibrinogen receptor expression and serotonin release by leupeptin and antipain.
The Journal of biological chemistry 1985;260(19):10531-5.
1985: Gary J Fisher; S Bakshian; Joseph J Baldassare
Activation of human platelets by ADP causes a rapid rise in cytosolic free calcium without hydrolysis of phosphatidylinositol-4,5-bisphosphate.
Biochemical and biophysical research communications 1985;129(3):958-64.
1983: Gary J Fisher; C E Freter; R C Ladenson; D F Silbert
Effect of membrane sterol content on the susceptibility of phospholipids to phospholipase A2.
The Journal of biological chemistry 1983;258(19):11705-12.
1983: Gary J Fisher; B M Sutherland; J C Sutherland
Action spectra for ultraviolet photosensitized killing of mammalian cells by misonidazole and para-nitroacetophenone.
Radiation research 1983;94(2):231-8.
1983: Gary J Fisher; E J Land
Photosensitization of pyrimidines by 2-methylnaphthoquinone in water: a laser flash photolysis study.
Photochemistry and photobiology 1983;37(1):27-32.
1982: Gary J Fisher; J L Gaylor
Kinetic investigation of rat liver microsomal electron transport from NADH to cytochrome P-450.
The Journal of biological chemistry 1982;257(13):7449-55.
1982: James M Trzaskos; W D Bowen; Gary J Fisher; J T Billheimer; J L Gaylor
Microsomal enzymes of cholesterol biosynthesis from lanosterol: a progress report.
Lipids 1982;17(3):250-6.
1981: Gary J Fisher; H Fukushima; J L Gaylor
Isolation, purification, and properties of a unique form of cytochrome P-450 in microsomes of isosafrole-treated rats.
The Journal of biological chemistry 1981;256(9):4388-94.
1978: Gary J Fisher; M E Watts; K B Patel; G E Adams
Sensitization of ultraviolet radiation damage in bacteria and mammalian cells.
The British journal of cancer. Supplement 1978;3():111-4.
1974: Gary J Fisher; A J Varghese; H E Johns
Ultraviolet-induced reactions of thymine and uracil in the presence of cysteine.
Photochemistry and photobiology 1974;20(2):109-20.
1970: Gary J Fisher; H E Johns
Ultraviolet photochemistry of thymine in aqueous solution.
Photochemistry and photobiology 1970;11(6):429-44.