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Harvey Fisher

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TOP 3
Harvey F Fisher
Detecting "silent" allosteric coupling.
Harvey F Fisher; Steven J Maniscalco; Jon Tally; Kayann Tabanor
Application of the second rule of transient-state kinetic isotope effects to an enzymatic mechanism.
Liskin Swint-Kruse; Harvey F Fisher
Enzymatic reaction sequences as coupled multiple traces on a multidimensional landscape.

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All Publications

2012: Harvey F Fisher
Detecting "silent" allosteric coupling.
Methods in molecular biology (Clifton, N.J.) 2012;796():71-96.
2009: Harvey F Fisher; Steven J Maniscalco; Jon Tally; Kayann Tabanor
Application of the second rule of transient-state kinetic isotope effects to an enzymatic mechanism.
Biochemistry 2009;48(51):12265-71.
2008: Liskin Swint-Kruse; Harvey F Fisher
Enzymatic reaction sequences as coupled multiple traces on a multidimensional landscape.
Trends in biochemical sciences 2008;33(3):104-12.
2006: Harvey F Fisher; Bruce A Palfey; Steven J Maniscalco; Lawrence Indyk
Relationship between the time-dependence of a transient-state kinetic isotope effect and the location of complexes in a reaction sequence.
The journal of physical chemistry. A 2006;110(13):4465-72.
2005: Harvey F Fisher
Transient-state kinetic approach to mechanisms of enzymatic catalysis.
Accounts of chemical research 2005;38(3):157-66.
2004: Steven J Maniscalco; Jon F Tally; Harvey F Fisher
The interpretation of multiple-step transient-state kinetic isotope effects.
Archives of biochemistry and biophysics 2004;425(2):165-72.
2003: Steven J Maniscalco; Jon F Tally; S Welsh Harris; Harvey F Fisher
The direct measurement of thermodynamic parameters of reactive transient intermediates of the L-glutamate dehydrogenase reaction.
The Journal of biological chemistry 2003;278(18):16129-34.
2002: Jon F Tally; Steven J Maniscalco; Swapan K Saha; Harvey F Fisher
Detection of multiple active site domain motions in transient-state component time courses of the Clostridium symbiosum L-glutamate dehydrogenase-catalyzed oxidative deamination reaction.
Biochemistry 2002;41(37):11284-93.
2002: Harvey F Fisher; Steven J Maniscalco
A close-packed planar 4-atom motif serves as a variable-pathway mechanistic switching device in enzymatic catalysis.
Bioorganic chemistry 2002;30(3):199-210.
2001: Harvey F Fisher; Steven J Maniscalco; Jon F Tally
Stabilization of noncovalent intermediates in enzymatically catalyzed reactions.
Biochemical and biophysical research communications 2001;287(2):343-7.
1999: Swapan K Saha; Harvey F Fisher
The location of active site opening and closing events in the prehydride transfer phase of the oxidative deamination reaction catalyzed by bovine liver glutamate dehydrogenase using a novel pH jump approach.
Biochimica et biophysica acta 1999;1431(1):261-5.
1998: Steven J Maniscalco; Swapan K Saha; Harvey F Fisher
Identification and characterization of kinetically competent carbinolamine and alpha-iminoglutarate complexes in the glutamate dehydrogenase-catalyzed oxidation of L-glutamate using a multiwavelength transient state approach.
Biochemistry 1998;37(41):14585-90.
1998: Swapan K Saha; Steven J Maniscalco; Harvey F Fisher
The use of multiwavelength kinetic analysis approach to identify and characterize intermediate complexes in the reductive amination reaction catalyzed by bovine liver glutamate dehydrogenase.
Biochimica et biophysica acta 1998;1382(1):8-12.
1998: L Indyk; Harvey F Fisher
Theoretical aspects of isothermal titration calorimetry.
Methods in enzymology 1998;295():350-64.
1998: Harvey F Fisher; Jon F Tally
Isoergonic cooperativity: a novel form of allostery.
Methods in enzymology 1998;295():331-49.
1997: Harvey F Fisher; Jon F Tally
Isoergonic cooperativity in glutamate dehydrogenase complexes: a new form of allostery.
Biochemistry 1997;36(36):10807-10.
1996: Swapan K Saha; Steven J Maniscalco; Harvey F Fisher
Mechanistic interpretation of tryptophan fluorescence quenching in the time courses of glutamate dehydrogenase catalyzed reactions.
Biochemistry 1996;35(51):16483-8.
1996: N Singh; Z Liu; Harvey F Fisher
The existence of a hexameric intermediate with molten-globule-like properties in the thermal denaturation of bovine-liver glutamate dehydrogenase.
Biophysical chemistry 1996;63(1):27-36.
1996: Steven J Maniscalco; Swapan K Saha; P Vicedomine; Harvey F Fisher
A difference in the sequence of steps in the reactions catalyzed by two closely homologous forms of glutamate dehydrogenase.
Biochemistry 1996;35(1):89-94.
1996: Harvey F Fisher; Swapan K Saha
Interpretation of transient-state kinetic isotope effects.
Biochemistry 1996;35(1):83-8.
1995: Harvey F Fisher; N Singh
Calorimetric methods for interpreting protein-ligand interactions.
Methods in enzymology 1995;259():194-221.
1994: Swapan K Saha; Steven J Maniscalco; N Singh; Harvey F Fisher
The demonstration of a glutamate dehydrogenase-NADP-L-glutamate charge-transfer complex and its location on the reaction pathway.
The Journal of biological chemistry 1994;269(47):29592-7.
1994: S Pazhanisamy; Steven J Maniscalco; N Singh; Harvey F Fisher
A kinetic mechanism of the allosteric control of enzyme-coenzyme binding: glutamate dehydrogenase-NADPH-phosphate-acetate-hydrogen ion interactions.
Biochemistry 1994;33(34):10381-5.
1994: N Singh; Harvey F Fisher
Protein-ligand interactions as a driving force for a high-enthalpy two-state transition in glutamate dehydrogenase: the opposing roles of phosphate and acetate ions.
Archives of biochemistry and biophysics 1994;312(1):38-44.
1993: N Singh; Steven J Maniscalco; Harvey F Fisher
The real-time resolution of proton-related transient-state steps in an enzymatic reaction. The early steps in the oxidative deamination reaction of bovine liver glutamate dehydrogenase.
The Journal of biological chemistry 1993;268(1):21-8.
1992: Harvey F Fisher; Steven J Maniscalco; N Singh; R N Mehrotra; R Srinivasan
A slow obligatory proton release step precedes hydride transfer in the liver glutamate dehydrogenase catalytic mechanism.
Biochimica et biophysica acta 1992;1119(1):52-6.
1991: Harvey F Fisher; N Singh
Transduction of enzyme-ligand binding energy into catalytic driving force.
FEBS letters 1991;294(1-2):1-5.
1988: Harvey F Fisher; Steven J Maniscalco; N Singh; S A Adediran
Proton/product time course ratios: a new approach to transient-state kinetic analysis.
The Journal of biological chemistry 1988;263(24):11704-10.
1988: R Srinivasan; T S Viswanathan; Harvey F Fisher
Mechanism of formation of bound alpha-iminoglutarate from alpha-ketoglutarate in the glutamate dehydrogenase reaction. A chemical basis for ammonia recognition.
The Journal of biological chemistry 1988;263(5):2304-8.
1988: Harvey F Fisher
A unifying model of the thermodynamics of formation of dehydrogenase-ligand complexes.
Advances in enzymology and related areas of molecular biology 1988;61():1-46.
1987: Harvey F Fisher; S Pazhanisamy; R T Medary
The anomalous properties of the glutamate dehydrogenase-NADPH-alpha-ketoglutarate complex are not ascribable to a carbonyl addition reaction.
The Journal of biological chemistry 1987;262(24):11684-7.
1987: P Chalabi; Steven J Maniscalco; L E Cohn; Harvey F Fisher
The effects of an acetate-sensitive anion binding site on NADPH binding in glutamate dehydrogenase.
Biochimica et biophysica acta 1987;913(2):103-10.
1986: Harvey F Fisher; Steven J Maniscalco; C Wolfe; R Srinivasan
NADPH binding induced proton ionization as a cause of nonlinear heat capacity changes in glutamate dehydrogenase.
Biochemistry 1986;25(10):2910-5.
1984: Harvey F Fisher; T S Viswanathan
Carbonyl oxygen exchange evidence of imine formation in the glutamate dehydrogenase reaction and identification of the "occult role" of NADPH.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(9):2747-51.
1984: Harvey F Fisher; R T Medary; E J Wykes; C S Wolfe
Thermodynamic interactions in the glutamate dehydrogenase-NADPH-oxalylglycine complex.
The Journal of biological chemistry 1984;259(7):4105-10.
1982: A H Colen; R E Johnson; Harvey F Fisher
Effect of cryosolvent on transient kinetics of the glutamate dehydrogenase reaction.
Biochemistry 1982;21(26):6695-9.
1982: T S Viswanathan; C E Hignite; Harvey F Fisher
Determination of carbonyl oxygen exchange rates in alpha-ketoacids by gas chromatography-mass spectrometry.
Analytical biochemistry 1982;123(2):295-302.
1982: T S Viswanathan; R E Johnson; Harvey F Fisher
alpha-Ketoglutaric acid: solution structure and the active form for reductive amination by bovine liver glutamate dehydrogenase.
Biochemistry 1982;21(2):339-45.
1981: Harvey F Fisher; A H Colen; R T Medary
Temperature-dependent delta C0p generated by a shift in equilibrium between macrostates of an enzyme.
Nature 1981;292(5820):271-2.
1981: A H Colen; R T Medary; Harvey F Fisher
Transient-phase energetics of the oxidative deamination of L-glutamate by L-glutamate dehydrogenase and NADP: a reaction with a large negative heat capacity of activation.
Biopolymers 1981;20(5):879-89.
1980: Harvey F Fisher; D C Stickel; A H Colen
pH-dependent thermodynamic parameters of the glutamate dehydrogenase-alpha-ketoglutarate-NADPH complex.
Biochimica et biophysica acta 1980;615(1):27-33.
1980: Harvey F Fisher; D C Stickel
Thermodynamic interaction parameters of a reactive enzyme ternary complex: glutamate dehydrogenase--NADPH--alpha-ketoglutarate.
FEBS letters 1980;113(1):11-4.
1980: Harvey F Fisher; S Subramanian; D C Stickel; A H Colen
The thermodynamics of a negatively interacting allosteric effector system. The glutamate dehydrogenase . NADPH . ADP complexes.
The Journal of biological chemistry 1980;255(6):2509-13.