FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Paul Fisher

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Genes & Molecular Sequences

Genes, Tumor Suppressor

Physiology

Procedures

Genetic Therapy

Disorders

Concepts & Ideas

Molecular Sequence Data

Co-author Network

Publications

TOP 3
Dong Chen; David T Curiel; Igor Dmitriev; Luni Emdad; Paul B Fisher; Rachel Gredler; Elena A Kashentseva; Devaraja Rajasekaran; Chadia L Robertson; Prasanna K. Santhekadur; Xue-Ning Shen; Ayesha Siddiq; Jyoti Srivastava; Devanand Sarkar
Insulin-like growth factor-binding protein-7 (IGFBP7): a promising gene therapeutic for hepatocellular carcinoma (HCC).
Hyun Yong Jeon; Sung-Hoon Kim; Seok-Geun Lee; Devanand Sarkar; Swadesh K Das; Santanu Dasgupta; Luni Emdad; Paul B Fisher
Expression patterns of MDA-9/syntenin during development of the mouse embryo.
Santanu Dasgupta; Paul B Fisher; Adi F Gazdar; Mohammad Hoque; Jin Sung Jang; Jin Jen; Stephan Lam; Nitai D Mukhopadhyay; Chunbo Shao; Upneet K Sokhi; C Conover Talbot; William H Westra; Ping Yang; Joanne E Yi; Rex C-W Yung; Shahnaz Begum; Mariana Brait; Swadesh K Das; David Sidransky
SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Paul Fisher (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Dong Chen; David T Curiel; Igor Dmitriev; Luni Emdad; Paul B Fisher; Rachel Gredler; Elena A Kashentseva; Devaraja Rajasekaran; Chadia L Robertson; Prasanna K. Santhekadur; Xue-Ning Shen; Ayesha Siddiq; Jyoti Srivastava; Devanand Sarkar
Insulin-like growth factor-binding protein-7 (IGFBP7): a promising gene therapeutic for hepatocellular carcinoma (HCC).
Molecular therapy : the journal of the American Society of Gene Therapy 2013;21(4):758-66.
2013: Hyun Yong Jeon; Sung-Hoon Kim; Seok-Geun Lee; Devanand Sarkar; Swadesh K Das; Santanu Dasgupta; Luni Emdad; Paul B Fisher
Expression patterns of MDA-9/syntenin during development of the mouse embryo.
Journal of molecular histology 2013;44(2):159-66.
2013: Santanu Dasgupta; Paul B Fisher; Adi F Gazdar; Mohammad Hoque; Jin Sung Jang; Jin Jen; Stephan Lam; Nitai D Mukhopadhyay; Chunbo Shao; Upneet K Sokhi; C Conover Talbot; William H Westra; Ping Yang; Joanne E Yi; Rex C-W Yung; Shahnaz Begum; Mariana Brait; Swadesh K Das; David Sidransky
SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling.
Journal of molecular medicine (Berlin, Germany) 2013;91(3):381-93.
2013: Swadesh K Das; Santanu Dasgupta; Rupesh Dash; Paul Dent; Luni Emdad; Steven Grant; Timothy P Kegelman; Leyla Peachy; Maurizio Pellecchia; Prasanna K. Santhekadur; Devanand Sarkar; Belal Azab; Sujit K Bhutia; Paul B Fisher
MDA-9/syntenin and IGFBP-2 promote angiogenesis in human melanoma.
Cancer research 2013;73(2):844-54.
2013: Shashi Rajput; Prasanna K. Santhekadur; Devanand Sarkar; Siddik Sarkar; Belal Azab; Subhasis Das; Swadesh K Das; Luni Emdad; Paul B Fisher; B N Prashanth Kumar; Mahitosh Mandal
Targeted Apoptotic Effects of Thymoquinone and Tamoxifen on XIAP Mediated Akt Regulation in Breast Cancer.
PloS one 2013;8(4):e61342.
2013: Shibu Thomas; Xiang-Yang Wang; Swadesh K Das; Santanu Dasgupta; Rupesh Dash; Paul Dent; Luni Emdad; Maurizio Pellecchia; Bridget A Quinn; John C Reed; Devanand Sarkar; Paul B Fisher
Targeting the Bcl-2 family for cancer therapy.
Expert opinion on therapeutic targets 2013;17(1):61-75.
2013: Si Wang; Bainan Wu; Ziming Zhang; John L Stebbins; Neil A Bhowmick; Sandrine Billet; Swadesh Das; Ana Fernandez; Paul B Fisher; Shinichi Kitada; Sayantan Mitra; Roberta Noberini; Elena B Pasquale; Maurizio Pellecchia
Targeted delivery of paclitaxel to EphA2-expressing cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(1):128-37.
2012: Michael Hedvat; Bin Hu; Timothy P Kegelman; Keetae Kim; Mitchell E Menezes; Regina A Oyesanya; Maurizio Pellecchia; Martin G Pomper; Bridget A Quinn; John C Reed; Devanand Sarkar; Siddik Sarkar; Upneet K Sokhi; John L Stebbins; Shibu Thomas; Xiang-Yang Wang; Jun Wei; Bainan Wu; Shan Zhu; Praveen Bhoopathi; Swadesh K Das; Santanu Dasgupta; Rupesh Dash; Paul W Diaz; Luni Emdad; Eda Erdogan; Paul B Fisher
Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules.
Anti-cancer agents in medicinal chemistry 2012;12(9):1143-55.
2012: Chunqing Guo; Ross B Mikkelsen; Jie Qian; John R Subjeck; Xiaolei Sun; Gary Yang; Huanfa Yi; Xiaofei Yu; Daming Zuo; Paul B Fisher; Barbara A Foster; Xiang-Yang Wang
In situ vaccination with CD204 gene-silenced dendritic cell, not unmodified dendritic cell, enhances radiation therapy of prostate cancer.
Molecular cancer therapeutics 2012;11(11):2331-41.
2012: Jyoti Srivastava; Jillian Stafflinger; Mark A Subler; Jolene J Windle; Khalid Shah; Xue-Ning Shen; Ayesha Siddiq; Rushdy Ahmad; Deepak Bhere; Dong Chen; Catherine I Dumur; Luni Emdad; Paul B Fisher; Shah Giashuddin; Rachel Gredler; Phillip B Hylemon; Nitai D Mukhopadhyay; Chadia L Robertson; Prasanna K. Santhekadur; Devanand Sarkar
Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model.
Hepatology (Baltimore, Md.) 2012;56(5):1782-91.
2012: Santanu Dasgupta; David P Duberow; Paul B Fisher; Thomas E Keane; Lambertus A Kiemeney; Richard A Mathies; Chunbo Shao; David Sidransky
Detection of mitochondrial deoxyribonucleic acid alterations in urine from urothelial cell carcinoma patients.
International journal of cancer. Journal international du cancer 2012;131(1):158-64.
2012: Santanu Dasgupta; Paul B Fisher; Adi F Gazdar; Stephan Lam; Reddy v Praveen; Nitai Mukhopadhyay; Chunbo Shao; Ethan Soudry; John Yee; Wei Zhang; David Sidransky
Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutation.
Journal of cellular physiology 2012;227(6):2451-60.
2012: Nichola Cruickshanks; M Danielle Bareford; Paul B Fisher; Steven Grant; Hossein A Hamed; Andrew Poklepovic; Paul Dent
Lapatinib and obatoclax kill tumor cells through blockade of ERBB1/3/4 and through inhibition of BCL-XL and MCL-1.
Molecular pharmacology 2012;81(5):748-58.
2012: Belal Azab; Sujit K Bhutia; David T Curiel; Swadesh K Das; Rupesh Dash; Paul Dent; Igor P Dmitriev; Steven Grant; Michael Hedvat; Maurizio Pellecchia; Bridget A Quinn; John C Reed; Devanand Sarkar; Siddik Sarkar; Xue-Ning Shen; Xiang-Yang Wang; Paul B Fisher
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells.
Journal of cellular physiology 2012;227(5):2145-53.
2012: Sujit K Bhutia; David T Curiel; Swadesh K Das; Rupesh Dash; Paul Dent; Steven Grant; Timothy P Kegelman; Seok-Geun Lee; Federica Rizzi; Devanand Sarkar; Zhao-Zhong Su; Xiang-Yang Wang; Belal Azab; Saverio Bettuzzi; Paul B Fisher
mda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer.
Journal of cellular physiology 2012;227(5):1805-13.
2012: Prasanna K. Santhekadur; Jyoti Srivastava; Albert S Baldwin; Dong Chen; Swadesh K Das; Paul B Fisher; Rachel Gredler; Chadia Robertson; Devanand Sarkar
Multifunction protein staphylococcal nuclease domain containing 1 (SND1) promotes tumor angiogenesis in human hepatocellular carcinoma through novel pathway that involves nuclear factor κB and miR-221.
The Journal of biological chemistry 2012;287(17):13952-8.
2012: Luni Emdad; Paul Dent; Devanand Sarkar; Paul B Fisher
Future approaches for the therapy of malignant glioma: targeting genes mediating invasion.
Future oncology (London, England) 2012;8(4):343-6.
2012: Yong Tang; Nichola Cruickshanks; Paul B Fisher; Steven Grant; Hossein A Hamed; Paul Dent
Obatoclax and lapatinib interact to induce toxic autophagy through NOXA.
Molecular pharmacology 2012;81(4):527-40.
2012: Daming Zuo; Huanfa Yi; Xiaofei Yu; Xing Chen; Zhengliang Chen; Daniel H Conrad; Paul B Fisher; Chunqing Guo; Tai L Guo; John R Subjeck; Xiang-Yang Wang
Molecular chaperoning by glucose-regulated protein 170 in the extracellular milieu promotes macrophage-mediated pathogen sensing and innate immunity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(4):1493-505.
2012: Santanu Dasgupta; Rupesh Dash; Swadesh K Das; Devanand Sarkar; Paul B Fisher
Emerging strategies for the early detection and prevention of head and neck squamous cell cancer.
Journal of cellular physiology 2012;227(2):467-73.
2012: Prasanna K. Santhekadur; Xue-Ning Shen; Ayesha Siddiq; Dong Chen; Swadesh K Das; Luni Emdad; Paul B Fisher; Rachel Gredler; Devanand Sarkar
Late SV40 factor (LSF) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP-9).
The Journal of biological chemistry 2012;287(5):3425-32.
2012: Swadesh K Das; Rupesh Dash; Paul Dent; Devanand Sarkar; Siddik Sarkar; Xiang-Yang Wang; Paul B Fisher
Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.
Advances in cancer research 2012;115():1-38.
2012: Prasanna K. Santhekadur; Scott E Schaus; Ayesha Siddiq; Dong Chen; Paul B Fisher; Rachel Gredler; Ulla Hansen; Devaraja Rajasekaran; Devanand Sarkar
The transcription factor LSF: a novel oncogene for hepatocellular carcinoma.
American journal of cancer research 2012;2(3):269-85.
2011: Byoung Kwon Yoo; Dong Chen; Paul B Fisher; Rachel Gredler; Prasanna K. Santhekadur; Devanand Sarkar
c-Met activation through a novel pathway involving osteopontin mediates oncogenesis by the transcription factor LSF.
Journal of hepatology 2011;55(6):1317-24.
2011: Dong Chen; Swadesh K Das; Paul B Fisher; Christine Fuller; Rachel Gredler; Prasanna K. Santhekadur; Zao-Zhong Su; Byoung Kwon Yoo; Sujit K Bhutia; Devanand Sarkar
Insulin-like growth factor-binding protein-7 functions as a potential tumor suppressor in hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(21):6693-701.
2011: Devanand Sarkar; Xiang-Yang Wang; Paul B Fisher
Targeting JunD: a potential strategy to counteract hormone-refractory prostate cancer.
Cell cycle (Georgetown, Tex.) 2011;10(20):3433.
2011: Seok-Geun Lee; Devanand Sarkar; Zao-Zhong Su; Byoung Kwon Yoo; Jung-Kyoung Choi; Swadesh K Das; Rupesh Dash; Luni Emdad; Eric L Howlett; Hyun Yong Jeon; Dong-Chul Kang; Timothy P Kegelman; Keetae Kim; Sung-Hoon Kim; Paul B Fisher
Oncogene AEG-1 promotes glioma-induced neurodegeneration by increasing glutamate excitotoxicity.
Cancer research 2011;71(20):6514-23.
2011: Bridget A Quinn; Mohamed Rahmani; John C Reed; Devanand Sarkar; Siddik Sarkar; John L Stebbins; Jun Wei; Bainan Wu; Belal Azab; David T Curiel; Swadesh K Das; Santanu Dasgupta; Rupesh Dash; Paul Dent; Igor Dmitriev; Steven Grant; Michael Hedvat; Sachin Kumar; Regina A Oyesanya; Maurizio Pellecchia; Paul B Fisher
Targeting Mcl-1 for the therapy of cancer.
Expert opinion on investigational drugs 2011;20(10):1397-411.
2011: M Danielle Bareford; Matthew E Burow; Nichola Cruickshanks; Paul B Fisher; Steven Grant; Hossein A Hamed; Richard G Moran; Kenneth P Nephew; Yong Tang; Paul Dent
Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells.
Autophagy 2011;7(10):1261-2.
2011: Keetae Kim; Seok-Geun Lee; Maurizio Pellecchia; John C Reed; Devanand Sarkar; John L Stebbins; Zao-Zhong Su; Paola M Barral; Swadesh K Das; Santanu Dasgupta; Rupesh Dash; Paul Diaz; Michael Hedvat; Timothy P Kegelman; Paul B Fisher
Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics.
Journal of cellular physiology 2011;226(10):2484-93.
2011: Paul Dent; David T Curiel; Paul B Fisher
The potential of virus-based gene therapies for treatment of metastatic kidney cancer.
Expert review of anticancer therapy 2011;11(6):809-11.
2011: Rupesh Dash; Belal Azab; Bridget A Quinn; Xuening Shen; Xiang-Yang Wang; Swadesh K Das; Mohamed Rahmani; Jun Wei; Michael Hedvat; Paul Dent; Igor P Dmitriev; David T Curiel; Steven Grant; Bainan Wu; John L Stebbins; Maurizio Pellecchia; John C Reed; Devanand Sarkar; Paul B Fisher
Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(21):8785-90.
2011: Byoung Kwon Yoo; Prasanna K. Santhekadur; Rachel Gredler; Dong Chen; Luni Emdad; Sujit Bhutia; Lewis Pannell; Paul B Fisher; Devanand Sarkar
Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2011;53(5):1538-48.
2011: Swadesh K Das; S K Bhutia; U K Sokhi; R Dash; B Azab; Devanand Sarkar; Paul B Fisher
Human polynucleotide phosphorylase (hPNPase(old-35)): an evolutionary conserved gene with an expanding repertoire of RNA degradation functions.
Oncogene 2011;30(15):1733-43.
2011: Paul Dent; Yong Tang; Adly Yacoub; Yun Dai; Paul B Fisher; Steven Grant
CHK1 inhibitors in combination chemotherapy: thinking beyond the cell cycle.
Molecular interventions 2011;11(2):133-40.
2011: Byoung Kwon Yoo; Luni Emdad; Seok-Geun Lee; Zao-Zhong Su; Prasanna K. Santhekadur; Dong Chen; Rachel Gredler; Paul B Fisher; Devanand Sarkar
Astrocyte elevated gene-1 (AEG-1): A multifunctional regulator of normal and abnormal physiology.
Pharmacology & therapeutics 2011;130(1):1-8.
2011: Margaret A Park; Hossein A Hamed; Clint Mitchell; Nichola Cruickshanks; Rupesh Dash; Jeremy C Allegood; Igor P Dmitriev; Gary Tye; Besim Ogretmen; Sarah Spiegel; Adly Yacoub; Steven Grant; David T Curiel; Paul B Fisher; Paul Dent
A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.
Molecular pharmacology 2011;79(3):368-80.
2011: Rupesh Dash; Belal Azab; Xue-Ning Shen; Upneet K Sokhi; Siddik Sarkar; Zhao-zhong Su; Xiang-Yang Wang; Pier Paolo Claudio; Paul Dent; Igor P Dmitriev; David T Curiel; Steven Grant; Devanand Sarkar; Paul B Fisher
Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic.
Discovery medicine 2011;11(56):46-56.
2011: Kim Mai Huynh; Jae-Won Soh; Rupesh Dash; Devanand Sarkar; Paul B Fisher; Dongchul Kang
FOXM1 expression mediates growth suppression during terminal differentiation of HO-1 human metastatic melanoma cells.
Journal of cellular physiology 2011;226(1):194-204.
2010: Sujit K Bhutia; Timothy P Kegelman; Swadesh K Das; Belal Azab; Zhao-Zhong Su; Seok-Geun Lee; Devanand Sarkar; Paul B Fisher
Astrocyte elevated gene-1 induces protective autophagy.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(51):22243-8.
2010: Patrick J Eulitt; Margaret A Park; Hamed Hossein; Nichola Cruikshanks; Chen Yang; Igor P Dmitriev; Adly Yacoub; David T Curiel; Paul B Fisher; Paul Dent
Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery.
Cancer biology & therapy 2010;10(12):1290-305.
2010: Mohamed Rahmani; Mandy Mayo; Rupesh Dash; Upneet Kaur Sokhi; Igor P Dmitriev; Devanand Sarkar; Paul Dent; David T Curiel; Paul B Fisher; Steven Grant
Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress.
Molecular pharmacology 2010;78(6):1096-104.
2010: Miho Murakami; Hideyo Ugai; Minghui Wang; Natalya Belousova; Paul Dent; Paul B Fisher; Joel N Glasgow; Maaike Everts; David T Curiel
An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populations.
Virology 2010;407(2):196-205.
2010: Paul Dent; Adly Yacoub; Hossein A Hamed; Margaret A Park; Rupesh Dash; Sujit K Bhutia; Devanand Sarkar; Xiang-Yang Wang; Pankaj Gupta; Luni Emdad; Irina V Lebedeva; Moira Sauane; Zao-Zhong Su; Mohamed Rahmani; William C Broaddus; Harold F Young; Maciej S Lesniak; Steven Grant; David T Curiel; Paul B Fisher
The development of MDA-7/IL-24 as a cancer therapeutic.
Pharmacology & therapeutics 2010;128(2):375-84.
2010: Rupesh Dash; Sujit K Bhutia; Belal Azab; Zao-Zhong Su; Bridget A Quinn; Timothy P Kegelmen; Swadesh K Das; Keetae Kim; Seok-Geun Lee; Margaret A Park; Adly Yacoub; Mohammed Rahmani; Luni Emdad; Igor P Dmitriev; Xiang-Yang Wang; Devanand Sarkar; Steven Grant; Paul Dent; David T Curiel; Paul B Fisher
mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.
Cytokine & growth factor reviews 2010;21(5):381-91.
2010: Hyun Yong Jeon; Murim Choi; Eric L Howlett; Nikollaq Vozhilla; Byoung Kwon Yoo; Joyce A Lloyd; Devanand Sarkar; Seok-Geun Lee; Paul B Fisher
Expression patterns of astrocyte elevated gene-1 (AEG-1) during development of the mouse embryo.
Gene expression patterns : GEP 2010;10(7-8):361-7.
2010: Paul Dent; Adly Yacoub; Hossein A Hamed; Margaret A Park; Rupesh Dash; Sujit K Bhutia; Devanand Sarkar; Pankaj Gupta; Luni Emdad; Irina V Lebedeva; Moira Sauane; Zao-Zhong Su; Mohamed Rahmani; William C Broaddus; Harold F Young; Maciej Lesniak; Steven Grant; David T Curiel; Paul B Fisher
MDA-7/IL-24 as a cancer therapeutic: from bench to bedside.
Anti-cancer drugs 2010;21(8):725-31.
2010: R Dash; Zao-Zhong Su; Seok-Geun Lee; B Azab; Habib Boukerche; Devanand Sarkar; Paul B Fisher
Inhibition of AP-1 by SARI negatively regulates transformation progression mediated by CCN1.
Oncogene 2010;29(31):4412-23.
2010: R Dash; I Dmitriev; Zao-Zhong Su; S K Bhutia; B Azab; N Vozhilla; Adly Yacoub; Paul Dent; David T Curiel; Devanand Sarkar; Paul B Fisher
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells.
Cancer gene therapy 2010;17(7):447-56.
2010: Swadesh K Das; Upneet K Sokhi; Sujit K Bhutia; Belal Azab; Zao-Zhong Su; Devanand Sarkar; Paul B Fisher
Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(26):11948-53.
2010: Hossein A Hamed; Adly Yacoub; Margaret A Park; Patrick J Eulitt; Rupesh Dash; Devanand Sarkar; Igor P Dmitriev; Maciej S Lesniak; Khalid Shah; Steven Grant; David T Curiel; Paul B Fisher; Paul Dent
Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(6):1130-42.
2010: Byoung Kwon Yoo; Luni Emdad; Rachel Gredler; Christine Fuller; Catherine I Dumur; Kimberly H Jones; Colleen Jackson-Cook; Zao-Zhong Su; Dong Chen; Utsav H Saxena; Ulla Hansen; Paul B Fisher; Devanand Sarkar
Transcription factor Late SV40 Factor (LSF) functions as an oncogene in hepatocellular carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(18):8357-62.
2010: Teneille Walker; Clint Mitchell; Margaret A Park; Adly Yacoub; Mohamed Rahmani; Dieter Häussinger; Roland Reinehr; Christina Voelkel Johnson; Paul B Fisher; Steven Grant; Paul Dent
17-allylamino-17-demethoxygeldanamycin and MEK1/2 inhibitors kill GI tumor cells via Ca2+-dependent suppression of GRP78/BiP and induction of ceramide and reactive oxygen species.
Molecular cancer therapeutics 2010;9(5):1378-95.
2010: Sujit K Bhutia; Rupesh Dash; Swadesh K Das; Belal Azab; Zao-Zhong Su; Seok-Geun Lee; Steven Grant; Adly Yacoub; Paul Dent; David T Curiel; Devanand Sarkar; Paul B Fisher
Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24.
Cancer research 2010;70(9):3667-76.
2010: Byoung Kwon Yoo; Dong Chen; Zao-Zhong Su; Rachel Gredler; Jinsang Yoo; Khalid Shah; Paul B Fisher; Devanand Sarkar
Molecular mechanism of chemoresistance by astrocyte elevated gene-1.
Cancer research 2010;70(8):3249-58.
2010: Hossein A Hamed; Adly Yacoub; Margaret A Park; Patrick Eulitt; Devanand Sarkar; Igor P Dimitrie; Ching-Shih Chen; Steven Grant; David T Curiel; Paul B Fisher; Paul Dent
OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins.
Cancer biology & therapy 2010;9(7):526-36.
2010: Moira Sauane; Zao-Zhong Su; Rupesh Dash; Xiang Liu; James S Norris; Devanand Sarkar; Seok-Geun Lee; Jeremy C Allegood; Paul Dent; Sarah Spiegel; Paul B Fisher
Ceramide plays a prominent role in MDA-7/IL-24-induced cancer-specific apoptosis.
Journal of cellular physiology 2010;222(3):546-55.
2010: Miho Murakami; Hideyo Ugai; Natalya Belousova; Alexander Pereboev; Paul Dent; Paul B Fisher; Maaike Everts; David T Curiel
Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells.
The Prostate 2010;70(4):362-76.
2010: Adly Yacoub; Hossein A Hamed; Jeremy C Allegood; Clint Mitchell; Sarah Spiegel; Maciej S Lesniak; Besim Ogretmen; Rupesh Dash; Devanand Sarkar; William C Broaddus; Steven Grant; David T Curiel; Paul B Fisher; Paul Dent
PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.
Cancer research 2010;70(3):1120-9.
2010: Adly Yacoub; Renyan Liu; Margaret A Park; Hossein A Hamed; Rupesh Dash; Danielle N Schramm; Devanand Sarkar; Igor P Dimitriev; Jessica K Bell; Steven Grant; Nicholas P Farrell; David T Curiel; Paul B Fisher; Paul Dent
Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells.
Molecular pharmacology 2010;77(2):298-310.
2010: Luni Emdad; Devanand Sarkar; Seok-Geun Lee; Zao-Zhong Su; Byoung Kwon Yoo; Rupesh Dash; Adly Yacoub; Christine E Fuller; Khalid Shah; Paul Dent; Jeffrey N Bruce; Paul B Fisher
Astrocyte elevated gene-1: a novel target for human glioma therapy.
Molecular cancer therapeutics 2010;9(1):79-88.
2009: Luni Emdad; Seok-Geun Lee; Zao-Zhong Su; Hyun Yong Jeon; Habib Boukerche; Devanand Sarkar; Paul B Fisher
Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(50):21300-5.
2009: Paul Dent; David T Curiel; Steven Grant; Paul B Fisher
Minting a new class of polo-like-kinase inhibitors.
Cancer biology & therapy 2009;8(24):2384-5.
2009: Devanand Sarkar; Luni Emdad; Seok-Geun Lee; Byoung Kwon Yoo; Zao-Zhong Su; Paul B Fisher
Astrocyte elevated gene-1: far more than just a gene regulated in astrocytes.
Cancer research 2009;69(22):8529-35.
2009: Paola M Barral; Devanand Sarkar; Zao-Zhong Su; Glen N Barber; Rob DeSalle; Vincent R Racaniello; Paul B Fisher
Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity.
Pharmacology & therapeutics 2009;124(2):219-34.
2009: Paola M Barral; Devanand Sarkar; Paul B Fisher; Vincent R Racaniello
RIG-I is cleaved during picornavirus infection.
Virology 2009;391(2):171-6.
2009: Byoung Kwon Yoo; Rachel Gredler; Nicollaq Vozhilla; Zao-Zhong Su; Dong Chen; Talitha Forcier; Khalid Shah; Utsav Saxena; Ulla Hansen; Paul B Fisher; Devanand Sarkar
Identification of genes conferring resistance to 5-fluorouracil.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(31):12938-43.
2009: Seok-Geun Lee; H-Y Jeon; Zao-Zhong Su; J E Richards; N Vozhilla; Devanand Sarkar; T Van Maerken; Paul B Fisher
Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma.
Oncogene 2009;28(26):2476-84.
2009: Paul Dent; David T Curiel; Paul B Fisher; Steven Grant
Synergistic combinations of signaling pathway inhibitors: mechanisms for improved cancer therapy.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2009;12(3):65-73.
2009: Tom Van Maerken; Devanand Sarkar; Frank Speleman; Paul Dent; William A Weiss; Paul B Fisher
Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma.
Journal of cellular physiology 2009;219(3):707-15.
2009: Margaret A Park; Teneille Walker; Aditi Pandya Martin; Jeremy C Allegood; Nicollaq Vozhilla; Luni Emdad; Devanand Sarkar; Mohamed Rahmani; Martin Graf; Adly Yacoub; Constantinos Koumenis; Sarah Spiegel; David T Curiel; Christina Voelkel Johnson; Steven Grant; Paul B Fisher; Paul Dent
MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.
Molecular cancer therapeutics 2009;8(5):1280-91.
2009: Michelle R Staudt; Anthony L Depass; Devanand Sarkar; Paul B Fisher
Model cell culture system for defining the molecular and biochemical events mediating terminal differentiation of human melanoma cells.
Journal of cellular physiology 2009;218(2):304-14.
2009: Paul Dent; Steven Grant; Paul B Fisher; David T Curiel
PI3K: A rational target for ovarian cancer therapy?
Cancer biology & therapy 2009;8(1):27-30.
2008: Zao-Zhong Su; Seok-Geun Lee; Luni Emdad; Irina V Lebdeva; Pankaj Gupta; Kristoffer Valerie; Devanand Sarkar; Paul B Fisher
Cloning and characterization of SARI (suppressor of AP-1, regulated by IFN).
Proceedings of the National Academy of Sciences of the United States of America 2008;105(52):20906-11.
2008: Devanand Sarkar; Rob DeSalle; Paul B Fisher
Evolution of MDA-5/RIG-I-dependent innate immunity: independent evolution by domain grafting.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(44):17040-5.
2008: Habib Boukerche; Zao-Zhong Su; Célia Prévot; Devanand Sarkar; Paul B Fisher
mda-9/Syntenin promotes metastasis in human melanoma cells by activating c-Src.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(41):15914-9.
2008: Margaret A Park; Guo Zhang; Aditi Pandya Martin; Hossein Hamed; Clint Mitchell; Phillip B Hylemon; Martin Graf; Mohamed Rahmani; Kevin Ryan; Xiang Liu; Sarah Spiegel; James Norris; Paul B Fisher; Steven Grant; Paul Dent
Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation.
Cancer biology & therapy 2008;7(10):1648-62.
2008: Margaret A Park; Guo Zhang; James Norris; Phillip B Hylemon; Paul B Fisher; Steven Grant; Paul Dent
Regulation of autophagy by ceramide-CD95-PERK signaling.
Autophagy 2008;4(7):929-31.
2008: Irina Lebedeva; Zao-Zhong Su; Nicolaq Vozhilla; Lejuan Chatman; Devanand Sarkar; Paul Dent; Mohammad Athar; Paul B Fisher
Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol.
Cancer research 2008;68(18):7439-47.
2008: Guo Zhang; Margaret A Park; Clint Mitchell; Teneille Walker; Hossein Hamed; Elaine Studer; Martin Graf; Mohamed Rahmani; Seema Gupta; Phillip B Hylemon; Paul B Fisher; Steven Grant; Paul Dent
Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
The Journal of biological chemistry 2008;283(36):24343-58.
2008: Margaret A Park; Guo Zhang; Clint Mitchell; Mohamed Rahmani; Hossein Hamed; Michael P Hagan; Adly Yacoub; David T Curiel; Paul B Fisher; Steven Grant; Paul Dent
Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95.
Molecular cancer therapeutics 2008;7(9):2633-48.
2008: Guo Zhang; Margaret A Park; Clint Mitchell; Hossein Hamed; Mohamed Rahmani; Aditi Pandya Martin; David T Curiel; Adly Yacoub; Martin Graf; Ray Lee; John D Roberts; Paul B Fisher; Steven Grant; Paul Dent
Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(17):5385-99.
2008: Paul Dent; Adly Yacoub; Margaret Park; Devanand Sarkar; Khalid Shah; David T Curiel; Steven Grant; Paul B Fisher
Searching for a cure: gene therapy for glioblastoma.
Cancer biology & therapy 2008;7(9):1335-40.
2008: Aditi Pandya Martin; Anna Miller; Luni Emad; Mohamed Rahmani; Teneille Walker; Clint Mitchell; Michael P Hagan; Margaret A Park; Adly Yacoub; Paul B Fisher; Steven Grant; Paul Dent
Lapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression and decreased BAK activation and not by ERBB receptor kinase mutation.
Molecular pharmacology 2008;74(3):807-22.
2008: Moira Sauane; Zao-Zhong Su; Pankaj Gupta; Irina Lebedeva; Paul Dent; Devanand Sarkar; Paul B Fisher
Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9763-8.
2008: Irina Lebedeva; Zao-Zhong Su; Nichollaq Vozhilla; Lejuan Chatman; Devanand Sarkar; Paul Dent; Mohammad Athar; Paul B Fisher
Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis.
Molecular cancer therapeutics 2008;7(7):2042-50.
2008: Yuko Tsuruta; Larisa Pereboeva; Martina Breidenbach; Daniel T Rein; Minghui Wang; Ronald D Alvarez; Gene P Siegal; Paul Dent; Paul B Fisher; David T Curiel
A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(11):3582-8.
2008: Adly Yacoub; Hossein Hamed; Luni Emdad; Wagner Dos Santos; Pankaj Gupta; William C Broaddus; Viswanathan Ramakrishnan; Devanand Sarkar; Khalid Shah; David T Curiel; Steven Grant; Paul B Fisher; Paul Dent
MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors.
Cancer biology & therapy 2008;7(6):917-33.
2008: Pankaj Gupta; Luni Emdad; Irina Lebedeva; Devanand Sarkar; Paul Dent; David T Curiel; Jeffrey Settleman; Paul B Fisher
Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva.
Journal of cellular physiology 2008;215(3):827-36.
2008: C P L Paul; Maaike Everts; Joel N Glasgow; Paul Dent; Paul B Fisher; Ilya V Ulasov; Maciej S. Lesniak; Mariam A Stoff-Khalili; Justin Roth; M A Preuss; C M F Dirven; M L M Lamfers; Gene P Siegal; Zeng B Zhu; David T Curiel
Characterization of infectivity of knob-modified adenoviral vectors in glioma.
Cancer biology & therapy 2008;7(5):786-93.
2008: Devanand Sarkar; Habib Boukerche; Zao-Zhong Su; Paul B Fisher
mda-9/Syntenin: more than just a simple adapter protein when it comes to cancer metastasis.
Cancer research 2008;68(9):3087-93.
2008: Devanand Sarkar; Zao-Zhong Su; Eun Sook Park; Nicolaq Vozhilla; Paul Dent; David T Curiel; Paul B Fisher
A cancer terminator virus eradicates both primary and distant human melanomas.
Cancer gene therapy 2008;15(5):293-302.
2008: Margaret A Park; Adly Yacoub; Devanand Sarkar; Luni Emdad; Mohamed Rahmani; Sarah Spiegel; Constantinos Koumenis; Martin Graf; David T Curiel; Steven Grant; Paul B Fisher; Paul Dent
PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells.
Autophagy 2008;4(4):513-5.
2008: Isaac Chan; Irina Lebedeva; Zao-Zhong Su; Devanand Sarkar; Kristoffer Valerie; Paul B Fisher
Progression elevated gene-3 promoter (PEG-Prom) confers cancer cell selectivity to human polynucleotide phosphorylase (hPNPase(old-35))-mediated growth suppression.
Journal of cellular physiology 2008;215(2):401-9.
2008: Hossein Hamed; Clint Mitchell; Margaret A Park; David Hanna; Aditi Pandya Martin; Benjamin Harrison; William Hawkins; David A Curiel; Paul B Fisher; Steven Grant; Adly Yacoub; Michael P Hagan; Paul Dent
Human chorionic gonadotropin (hCG) interacts with lovastatin and ionizing radiation to modulate prostate cancer cell viability in vivo.
Cancer biology & therapy 2008;7(4):587-93.
2008: Margaret A Park; David T Curiel; Constantinos Koumenis; Martin Graf; Ching-Shih Chen; Paul B Fisher; Steven Grant; Paul Dent
PERK-dependent regulation of HSP70 expression and the regulation of autophagy.
Autophagy 2008;4(3):364-7.
2008: Margaret A Park; Adly Yacoub; Mohamed Rahmani; Guo Zhang; Lori Hart; Michael P Hagan; Stuart K Calderwood; Michael Y Sherman; Constantinos Koumenis; Sarah Spiegel; Ching-Shih Chen; Martin Graf; David T Curiel; Paul B Fisher; Steven Grant; Paul Dent
OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells.
Molecular pharmacology 2008;73(4):1168-84.
2008: Devanand Sarkar; Eun Sook Park; Luni Emdad; Seok-Geun Lee; Zao-Zhong Su; Paul B Fisher
Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1.
Cancer research 2008;68(5):1478-84.
2008: Seok-Geun Lee; Zao-Zhong Su; Luni Emdad; Devanand Sarkar; T F Franke; Paul B Fisher
Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling.
Oncogene 2008;27(8):1114-21.
2008: Adly Yacoub; Pankaj Gupta; Margaret A Park; Mohammed Rhamani; Hossein Hamed; David Hanna; Guo Zhang; Devanand Sarkar; Irina Lebedeva; Luni Emdad; Constantinos Koumenis; David T Curiel; Steven Grant; Paul B Fisher; Paul Dent
Regulation of GST-MDA-7 toxicity in human glioblastoma cells by ERBB1, ERK1/2, PI3K, and JNK1-3 pathway signaling.
Molecular cancer therapeutics 2008;7(2):314-29.
2008: Adly Yacoub; Margaret A Park; Pankaj Gupta; Mohamed Rahmani; Guo Zhang; Hossein Hamed; David Hanna; Devanand Sarkar; Irina Lebedeva; Luni Emdad; Moira Sauane; Nicollaq Vozhilla; Sarah Spiegel; Constantinos Koumenis; Martin Graf; David T Curiel; Steven Grant; Paul B Fisher; Paul Dent
Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells.
Molecular cancer therapeutics 2008;7(2):297-313.
2008: Francisca C Almeida; Magdalena Leszczyniecka; Paul B Fisher; Rob DeSalle
Examining ancient inter-domain horizontal gene transfer.
Evolutionary bioinformatics online 2008;4():109-19.
2008: Devanand Sarkar; Paul Dent; David T Curiel; Paul B Fisher
Acquired and innate resistance to the cancer-specific apoptosis-inducing cytokine, mda-7/IL-24: not insurmountable therapeutic problems.
Cancer biology & therapy 2008;7(1):109-12.
2007: Clint Mitchell; Margaret A Park; Guo Zhang; Adly Yacoub; David T Curiel; Paul B Fisher; John D Roberts; Steven Grant; Paul Dent
Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells.
Molecular cancer therapeutics 2007;6(12 Pt 1):3101-12.
2007: Luni Emdad; Irina Lebedeva; Zao-Zhong Su; Devanand Sarkar; Paul Dent; David T Curiel; Paul B Fisher
Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells.
Molecular cancer therapeutics 2007;6(11):2985-94.
2007: Zao-Zhong Su; Devanand Sarkar; Luni Emdad; Paola M Barral; Paul B Fisher
Central role of interferon regulatory factor-1 (IRF-1) in controlling retinoic acid inducible gene-I (RIG-I) expression.
Journal of cellular physiology 2007;213(2):502-10.
2007: Paul B Fisher; Devanand Sarkar; Irina Lebedeva; Luni Emdad; Pankaj Gupta; Moira Sauane; Zao-Zhong Su; Steven Grant; Paul Dent; David T Curiel; Neil Senzer; John Nemunaitis
Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.
Toxicology and applied pharmacology 2007;224(3):300-7.
2007: Devanand Sarkar; Eun Sook Park; Glen N Barber; Paul B Fisher
Activation of double-stranded RNA dependent protein kinase, a new pathway by which human polynucleotide phosphorylase (hPNPase(old-35)) induces apoptosis.
Cancer research 2007;67(17):7948-53.
2007: Clint Mitchell; Peyman Kabolizadeh; John Ryan; John D Roberts; Adly Yacoub; David T Curiel; Paul B Fisher; Michael P Hagan; Nicholas Farrell; Steven Grant; Paul Dent
Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Molecular pharmacology 2007;72(3):704-14.
2007: Devanand Sarkar; Irina Lebedeva; Zao-Zhong Su; Eun Sook Park; Lejuan Chatman; Nicolaq Vozhilla; Paul Dent; David T Curiel; Paul B Fisher
Eradication of therapy-resistant human prostate tumors using a cancer terminator virus.
Cancer research 2007;67(11):5434-42.
2007: Devanand Sarkar; Irina Lebedeva; Pankaj Gupta; Luni Emdad; Moira Sauane; Paul Dent; David T Curiel; Paul B Fisher
Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?
Expert opinion on biological therapy 2007;7(5):577-86.
2007: Yuko Tsuruta; Larisa Pereboeva; Joel N Glasgow; Daniel T Rein; Yosuke Kawakami; Ronald D Alvarez; Rodney P Rocconi; Gene P Siegal; Paul Dent; Paul B Fisher; David T Curiel
A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(9):2777-83.
2007: Luni Emdad; Devanand Sarkar; Zao-Zhong Su; Seok-Geun Lee; Dong-Chul Kang; Jeffrey N Bruce; David J Volsky; Paul B Fisher
Astrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration.
Pharmacology & therapeutics 2007;114(2):155-70.
2007: Paola M Barral; Juliet M Morrison; Jennifer Drahos; Pankaj Gupta; Devanand Sarkar; Paul B Fisher; Vincent Racaniello
MDA-5 is cleaved in poliovirus-infected cells.
Journal of virology 2007;81(8):3677-84.
2007: Kristoffer Valerie; Adly Yacoub; Michael P Hagan; David T Curiel; Paul B Fisher; Steven Grant; Paul Dent
Radiation-induced cell signaling: inside-out and outside-in.
Molecular cancer therapeutics 2007;6(3):789-801.
2007: Irina Lebedeva; Ilyas Washington; Devanand Sarkar; Jennifer A Clark; Robert L Fine; Paul Dent; David T Curiel; Nicholas J Turro; Paul B Fisher
Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3484-9.
2007: Habib Boukerche; Zao-Zhong Su; Luni Emdad; Devanand Sarkar; Paul B Fisher
mda-9/Syntenin regulates the metastatic phenotype in human melanoma cells by activating nuclear factor-kappaB.
Cancer research 2007;67(4):1812-22.
2007: David Paul Turner; Omar Moussa; Moira Sauane; Paul B Fisher; Dennis Watson
Prostate-derived ETS factor is a mediator of metastatic potential through the inhibition of migration and invasion in breast cancer.
Cancer research 2007;67(4):1618-25.
2007: Luni Emdad; Irina Lebedeva; Zao-Zhong Su; Pankaj Gupta; Devanand Sarkar; Jeffrey Settleman; Paul B Fisher
Combinatorial treatment of non-small-cell lung cancers with gefitinib and Ad.mda-7 enhances apoptosis-induction and reverses resistance to a single therapy.
Journal of cellular physiology 2007;210(2):549-59.
2007: Irina Lebedeva; Zao-Zhong Su; Luni Emdad; A Kolomeyer; Devanand Sarkar; Shinichi Kitada; Samuel Waxman; John C Reed; Paul B Fisher
Targeting inhibition of K-ras enhances Ad.mda-7-induced growth suppression and apoptosis in mutant K-ras colorectal cancer cells.
Oncogene 2007;26(5):733-44.
2007: Paul Dent; Philip B Hylemon; Steven Grant; Paul B Fisher
Approaches for monitoring signal transduction changes in normal and cancer cells.
Methods in molecular biology (Clifton, N.J.) 2007;383():259-76.
2007: Dong-Chul Kang; Paul B Fisher
Complete open reading frame (C-ORF) technique: rapid and efficient method for obtaining complete protein coding sequences.
Methods in molecular biology (Clifton, N.J.) 2007;383():123-33.
2007: Habib Boukerche; Zao-Zhong Su; Dong-Chul Kang; Paul B Fisher
Cloning differentially expressed genes using rapid subtraction hybridization (RaSH).
Methods in molecular biology (Clifton, N.J.) 2007;383():15-29.
2007: Devanand Sarkar; Dong-chul Kang; Paul B Fisher
Reciprocal subtraction differential RNA display (RSDD): an efficient technology for cloning differentially expressed genes.
Methods in molecular biology (Clifton, N.J.) 2007;383():1-14.
2007: Adly Yacoub; William Hawkins; David Hanna; Hong Young; Margaret A Park; Mark Grant; John D Roberts; David T Curiel; Paul B Fisher; Kristoffer Valerie; Steven Grant; Michael P Hagan; Paul Dent
Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment.
Molecular pharmacology 2007;71(1):259-75.
2006: Moira Sauane; Pankaj Gupta; Irina Lebedeva; Zao-Zhong Su; Devanand Sarkar; Aaron Randolph; Kristoffer Valerie; Rahul V Gopalkrishnan; Paul B Fisher
N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity.
Cancer research 2006;66(24):11869-77.
2006: Adly Yacoub; Anna Miller; Ruben Caron; Liang Qiao; David A Curiel; Paul B Fisher; Michael P Hagan; Steven Grant; Paul Dent
Radiotherapy-induced signal transduction.
Endocrine-related cancer 2006;13 Suppl 1():S99-114.
2006: Seok-Geun Lee; Zao-Zhong Su; Luni Emdad; Devanand Sarkar; Paul B Fisher
Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(46):17390-5.
2006: L Lin; Z Su; Irina Lebedeva; Pankaj Gupta; Habib Boukerche; T Rai; Glen N Barber; Paul Dent; Devanand Sarkar; Paul B Fisher
Activation of Ras/Raf protects cells from melanoma differentiation-associated gene-5-induced apoptosis.
Cell death and differentiation 2006;13(11):1982-93.
2006: Adly Yacoub; Donna Gilfor; William Hawkins; Margaret A Park; David Hanna; Michael P Hagan; David T Curiel; Paul B Fisher; Steven Grant; Paul Dent
MEK1/2 inhibition promotes Taxotere lethality in mammary tumors in vivo.
Cancer biology & therapy 2006;5(10):1332-9.
2006: Devanand Sarkar; Paul B Fisher
Polynucleotide phosphorylase: an evolutionary conserved gene with an expanding repertoire of functions.
Pharmacology & therapeutics 2006;112(1):243-63.
2006: Pankaj Gupta; Zao-Zhong Su; Irina Lebedeva; Devanand Sarkar; Moira Sauane; Luni Emdad; Michael A Bachelor; Steven Grant; David T Curiel; Paul Dent; Paul B Fisher
mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine.
Pharmacology & therapeutics 2006;111(3):596-628.
2006: Devanand Sarkar; Eun Sook Park; Paul B Fisher
Defining the mechanism by which IFN-beta dowregulates c-myc expression in human melanoma cells: pivotal role for human polynucleotide phosphorylase (hPNPaseold-35).
Cell death and differentiation 2006;13(9):1541-53.
2006: Pankaj Gupta; Mark R Walter; Zao-Zhong Su; Irina Lebedeva; Luni Emdad; Aaron Randolph; Kristoffer Valerie; Devanand Sarkar; Paul B Fisher
BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis.
Cancer research 2006;66(16):8182-91.
2006: Luni Emdad; Devanand Sarkar; Irina Lebedeva; Zao-Zhong Su; Pankaj Gupta; Parameshwar J Mahasreshti; Paul Dent; David T Curiel; Paul B Fisher
Ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer.
Journal of cellular physiology 2006;208(2):298-306.
2006: Devanand Sarkar; Zao-Zhong Su; Paul B Fisher
Unique conditionally replication competent bipartite adenoviruses-cancer terminator viruses (CTV): efficacious reagents for cancer gene therapy.
Cell cycle (Georgetown, Tex.) 2006;5(14):1531-6.
2006: Devanand Sarkar; Paul B Fisher
Regulation of Myc function by ARF: checkpoint for Myc-induced oncogenesis.
Cancer biology & therapy 2006;5(6):693-5.
2006: Devanand Sarkar; Paul B Fisher
Molecular mechanisms of aging-associated inflammation.
Cancer letters 2006;236(1):13-23.
2006: Devanand Sarkar; Paul B Fisher
Human polynucleotide phosphorylase (hPNPase old-35): an RNA degradation enzyme with pleiotrophic biological effects.
Cell cycle (Georgetown, Tex.) 2006;5(10):1080-4.
2006: Zao-Zhong Su; Irina Lebedeva; Devanand Sarkar; Luni Emdad; Pankaj Gupta; Shinichi Kitada; Paul Dent; John C Reed; Paul B Fisher
Ionizing radiation enhances therapeutic activity of mda-7/IL-24: overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2.
Oncogene 2006;25(16):2339-48.
2006: Parameshwar J Mahasreshti; Manjula Kataram; Hongju Wu; Laxmi Priya Yalavarthy; Delicia Carey; Paul B Fisher; Sunil Chada; Ronald D Alvarez; Hidde J Haisma; Paul Dent; David T Curiel
Ovarian cancer targeted adenoviral-mediated mda-7/IL-24 gene therapy.
Gynecologic oncology 2006;100(3):521-32.
2006: Irina Lebedeva; Devanand Sarkar; Zao-Zhong Su; Rahul V Gopalkrishnan; Mohammad Athar; Aaron Randolph; Kristoffer Valerie; Paul Dent; Paul B Fisher
Molecular target-based therapy of pancreatic cancer.
Cancer research 2006;66(4):2403-13.
2006: Luni Emdad; Devanand Sarkar; Zao-Zhong Su; Aaron Randolph; Habib Boukerche; Kristoffer Valerie; Paul B Fisher
Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis.
Cancer research 2006;66(3):1509-16.
2005: Habib Boukerche; Zao-Zhong Su; Luni Emdad; Patrick Baril; Brigitte Balme; Luc Thomas; Aaron Randolph; Kristoffer Valerie; Devanand Sarkar; Paul B Fisher
mda-9/Syntenin: a positive regulator of melanoma metastasis.
Cancer research 2005;65(23):10901-11.
2005: Zhaozhong Su; Luni Emdad; Moira Sauane; Irina Lebedeva; Devanand Sarkar; Pankaj Gupta; C David James; Aaron Randolph; Kristoffer Valerie; Mark R Walter; Paul Dent; Paul B Fisher
Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.
Oncogene 2005;24(51):7552-66.
2005: Paul B Fisher
Is mda-7/IL-24 a "magic bullet" for cancer?
Cancer research 2005;65(22):10128-38.
2005: Devanand Sarkar; Zao-Zhong Su; Nicolaq Vozhilla; Eun Sook Park; Aaron Randolph; Kristoffer Valerie; Paul B Fisher
Targeted virus replication plus immunotherapy eradicates primary and distant pancreatic tumors in nude mice.
Cancer research 2005;65(19):9056-63.
2005: Devanand Sarkar; Zao-Zhong Su; Nicolaq Vozhilla; Eun Sook Park; Pankaj Gupta; Paul B Fisher
Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(39):14034-9.
2005: Devanand Sarkar; Eun Sook Park; Luni Emdad; Aaron Randolph; Kristoffer Valerie; Paul B Fisher
Defining the domains of human polynucleotide phosphorylase (hPNPaseOLD-35) mediating cellular senescence.
Molecular and cellular biology 2005;25(16):7333-43.
2005: Paul Dent; Adly Yacoub; Steven Grant; David T Curiel; Paul B Fisher
MDA-7/IL-24 regulates proliferation, invasion and tumor cell radiosensitivity: a new cancer therapy?
Journal of cellular biochemistry 2005;95(4):712-9.
2005: Dong-Chul Kang; Zao-Zhong Su; Devanand Sarkar; Luni Emdad; David J Volsky; Paul B Fisher
Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1.
Gene 2005;353(1):8-15.
2005: Zao-Zhong Su; Luni Emdad; Devanand Sarkar; Aaron Randolph; Kristoffer Valerie; Adly Yacoub; Paul Dent; Paul B Fisher
Potential molecular mechanism for rodent tumorigenesis: mutational generation of Progression Elevated Gene-3 (PEG-3).
Oncogene 2005;24(13):2247-55.
2005: Zao-Zhong Su; Devanand Sarkar; Luni Emdad; Gregory J Duigou; C S H Young; Joy Ware; Aaron Randolph; Kristoffer Valerie; Paul B Fisher
Targeting gene expression selectively in cancer cells by using the progression-elevated gene-3 promoter.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(4):1059-64.
2005: Irina Lebedeva; Zao-Zhong Su; Devanand Sarkar; Rahul V Gopalkrishnan; Samuel Waxman; Adly Yacoub; Paul Dent; Paul B Fisher
Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis.
Oncogene 2005;24(4):585-96.
2005: Irina Lebedeva; Moira Sauane; Rahul V Gopalkrishnan; Devanand Sarkar; Zao-Zhong Su; Pankaj Gupta; John Nemunaitis; Casey Cunningham; Adly Yacoub; Paul Dent; Paul B Fisher
mda-7/IL-24: exploiting cancer's Achilles' heel.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(1):4-18.
2005: Luni Emdad; Devanand Sarkar; Zao-Zhong Su; Paul B Fisher
Emerging roles of centrosomal amplification and genomic instability in cancer.
Frontiers in bioscience : a journal and virtual library 2005;10():728-42.
2005: Luni Emdad; Devanand Sarkar; Zao-Zhong Su; Habib Boukerche; Menashe Bar-Eli; Paul B Fisher
Progression elevated gene-3 (PEG-3) induces pleiotropic effects on tumor progression: modulation of genomic stability and invasion.
Journal of cellular physiology 2005;202(1):135-46.
2004: Habib Boukerche; Zao-Zhong Su; Dong-Chul Kang; Paul B Fisher
Identification and cloning of genes displaying elevated expression as a consequence of metastatic progression in human melanoma cells by rapid subtraction hybridization.
Gene 2004;343(1):191-201.
2004: Devanand Sarkar; Habib Boukerche; Zao-Zhong Su; Paul B Fisher
mda-9/syntenin: recent insights into a novel cell signaling and metastasis-associated gene.
Pharmacology & therapeutics 2004;104(2):101-15.
2004: Devanand Sarkar; Irina Lebedeva; Luni Emdad; Dong-Chul Kang; Albert S Baldwin; Paul B Fisher
Human polynucleotide phosphorylase (hPNPaseold-35): a potential link between aging and inflammation.
Cancer research 2004;64(20):7473-8.
2004: Moira Sauane; Rahul V Gopalkrishnan; Heng-Tong Choo; Pankaj Gupta; Irina Lebedeva; Adly Yacoub; Paul Dent; Paul B Fisher
Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein.
Oncogene 2004;23(46):7679-90.
2004: Charles A Leath; Manjula Kataram; Pradeep Bhagavatula; Rahul V Gopalkrishnan; Paul Dent; Paul B Fisher; Alexander Pereboev; Delicia Carey; Irina Lebedeva; Hidde J Haisma; Ronald D Alvarez; David T Curiel; Parameshwar J Mahasreshti
Infectivity enhanced adenoviral-mediated mda-7/IL-24 gene therapy for ovarian carcinoma.
Gynecologic oncology 2004;94(2):352-62.
2004: Adly Yacoub; Clint Mitchell; Young Hong; Rahul V Gopalkrishnan; Zao-Zhong Su; Pankaj Gupta; Moria Sauane; Irina Lebedeva; David T Curiel; Parameshwar J Mahasreshti; Myrna R Rosenfeld; William C Broaddus; C David James; Steven Grant; Paul B Fisher; Paul Dent
MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells.
Cancer biology & therapy 2004;3(8):739-51.
2004: Moira Sauane; Irina Lebedeva; Zao-Zhong Su; Heng-tong Choo; Aaron Randolph; Kristoffer Valerie; Paul Dent; Rahul V Gopalkrishnan; Paul B Fisher
Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways.
Cancer research 2004;64(9):2988-93.
2004: Rahul V Gopalkrishnan; Moira Sauane; Paul B Fisher
Cytokine and tumor cell apoptosis inducing activity of mda-7/IL-24.
International immunopharmacology 2004;4(5):635-47.
2004: Magdalena Leszczyniecka; Rob DeSalle; Dong-Chul Kang; Paul B Fisher
The origin of polynucleotide phosphorylase domains.
Molecular phylogenetics and evolution 2004;31(1):123-30.
2004: Dong-Chul Kang; Rahul V Gopalkrishnan; Lin Lin; Aaron Randolph; Kristoffer Valerie; Sidney Pestka; Paul B Fisher
Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.
Oncogene 2004;23(9):1789-800.
2004: Zhuying Wang; Gusta Trillo-Pazos; Seon-Young Kim; Mario Canki; Susan Morgello; Leroy R Sharer; Harris A Gelbard; Zao-Zhong Su; Dong-Chul Kang; Andrew I Brooks; Paul B Fisher; David J Volsky
Effects of human immunodeficiency virus type 1 on astrocyte gene expression and function: potential role in neuropathogenesis.
Journal of neurovirology 2004;10 Suppl 1():25-32.
2003: Irina Lebedeva; Zao-Zhong Su; Devanand Sarkar; Shinichi Kitada; Paul Dent; Samuel Waxman; John C Reed; Paul B Fisher
Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.
Cancer research 2003;63(23):8138-44.
2003: Irina Lebedeva; Devanand Sarkar; Zao-Zhong Su; Shinichi Kitada; Paul Dent; Cy A Stein; John C Reed; Paul B Fisher
Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.
Oncogene 2003;22(54):8758-73.
2003: Magdalena Leszczyniecka; Zao-Zhong Su; Dong-Chul Kang; Devanand Sarkar; Paul B Fisher
Expression regulation and genomic organization of human polynucleotide phosphorylase, hPNPase(old-35), a Type I interferon inducible early response gene.
Gene 2003;316():143-56.
2003: Paul Dent; Adly Yacoub; Paul B Fisher; Michael P Hagan; Steven Grant
MAPK pathways in radiation responses.
Oncogene 2003;22(37):5885-96.
2003: Adly Yacoub; Clint Mitchell; Andrea Lister; Irina Lebedeva; Devanand Sarkar; Zao-Zhong Su; Carter Sigmon; Robert McKinstry; Viswanathan Ramakrishnan; Liang Qiao; William C Broaddus; Rahul V Gopalkrishnan; Steven Grant; Paul B Fisher; Paul Dent
Melanoma differentiation-associated 7 (interleukin 24) inhibits growth and enhances radiosensitivity of glioma cells in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3272-81.
2003: Moira Sauane; Rahul V Gopalkrishnan; Irina Lebedeva; Mei Xin Mei; Devanand Sarkar; Zao-Zhong Su; Dong-Chul Kang; Paul Dent; Sidney Pestka; Paul B Fisher
Mda-7/IL-24 induces apoptosis of diverse cancer cell lines through JAK/STAT-independent pathways.
Journal of cellular physiology 2003;196(2):334-45.
2003: Devanand Sarkar; Magdalena Leszczyniecka; Dong-Chul Kang; Irina Lebedeva; Kristoffer Valerie; Sonu Dhar; Tej K Pandita; Paul B Fisher
Down-regulation of Myc as a potential target for growth arrest induced by human polynucleotide phosphorylase (hPNPaseold-35) in human melanoma cells.
The Journal of biological chemistry 2003;278(27):24542-51.
2003: Adly Yacoub; Clint Mitchell; Irina Lebedeva; Devanand Sarkar; Zao-Zhong Su; Robert McKinstry; Rahul V Gopalkrishnan; Steven Grant; Paul B Fisher; Paul Dent
mda-7 (IL-24) Inhibits growth and enhances radiosensitivity of glioma cells in vitro via JNK signaling.
Cancer biology & therapy 2003;2(4):347-53.
2003: Paul B Fisher; Rahul V Gopalkrishnan; Sunil Chada; Rajagopal Ramesh; Elizabeth A Grimm; Myrna R Rosenfeld; David T Curiel; Paul Dent
mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic.
Cancer biology & therapy 2003;2(4 Suppl 1):S23-37.
2003: Adly Yacoub; Clint Mitchell; Jessica Brannon; Elizabeth Rosenberg; Liang Qiao; Robert McKinstry; W Marston Linehan; Zao-shong Su; Devanand Sarkar; Irina Lebedeva; Kristoffer Valerie; Rahul V Gopalkrishnan; Steven Grant; Paul B Fisher; Paul Dent
MDA-7 (interleukin-24) inhibits the proliferation of renal carcinoma cells and interacts with free radicals to promote cell death and loss of reproductive capacity.
Molecular cancer therapeutics 2003;2(7):623-32.
2003: Zao-Zhong Su; Dong-Chul Kang; Yinming Chen; Olga Pekarskaya; Wei Chao; David J Volsky; Paul B Fisher
Identification of gene products suppressed by human immunodeficiency virus type 1 infection or gp120 exposure of primary human astrocytes by rapid subtraction hybridization.
Journal of neurovirology 2003;9(3):372-89.
2003: Irina Lebedeva; Zao-Zhong Su; Devanand Sarkar; Paul B Fisher
Restoring apoptosis as a strategy for cancer gene therapy: focus on p53 and mda-7.
Seminars in cancer biology 2003;13(2):169-78.
2003: J Kevin Leach; Liang Qiao; Youwen Fang; Song L Y Han; Donna Gilfor; Paul B Fisher; Steven Grant; Phillip B Hylemon; Darrell Peterson; Paul Dent
Regulation of p21 and p27 expression by the hepatitis B virus X protein and the alternate initiation site X proteins, AUG2 and AUG3.
Journal of gastroenterology and hepatology 2003;18(4):376-85.
2003: Zao-Zhong Su; Yinming Chen; Dong-Chul Kang; Wei Chao; Malgorzata Simm; David J Volsky; Paul B Fisher
Customized rapid subtraction hybridization (RaSH) gene microarrays identify overlapping expression changes in human fetal astrocytes resulting from human immunodeficiency virus-1 infection or tumor necrosis factor-alpha treatment.
Gene 2003;306():67-78.
2003: Zao-Zhong Su; Irina Lebedeva; Devanand Sarkar; Rahul V Gopalkrishnan; Moira Sauane; Carter Sigmon; Adly Yacoub; Kristoffer Valerie; Paul Dent; Paul B Fisher
Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
Oncogene 2003;22(8):1164-80.
2003: Zao-Zhong Su; Magdalena Leszczyniecka; Dong-Chul Kang; Devanand Sarkar; Wei Chao; David J Volsky; Paul B Fisher
Insights into glutamate transport regulation in human astrocytes: cloning of the promoter for excitatory amino acid transporter 2 (EAAT2).
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1955-60.
2003: Moira Sauane; Rahul V Gopalkrishnan; Devanand Sarkar; Zao-Zhong Su; Irina Lebedeva; Paul Dent; Sidney Pestka; Paul B Fisher
MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine.
Cytokine & growth factor reviews 2003;14(1):35-51.
2003: Paul Dent; Liang Qiao; Donna Gilfor; Michael J Birrer; Steven Grant; Paul B Fisher
The regulation of tumor suppressor genes by oncogenes.
Methods in molecular biology (Clifton, N.J.) 2003;222():269-92.
2002: Magdalena Leszczyniecka; Dong-Chul Kang; Devanand Sarkar; Zao-Zhong Su; Matthew Holmes; Kristoffer Valerie; Paul B Fisher
Identification and cloning of human polynucleotide phosphorylase, hPNPase old-35, in the context of terminal differentiation and cellular senescence.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16636-41.
2002: Devanand Sarkar; Zao-Zhong Su; Irina Lebedeva; Moira Sauane; Rahul V Gopalkrishnan; Paul Dent; Paul B Fisher
mda-7 (IL-24): signaling and functional roles.
BioTechniques 2002;Suppl():30-9.
2002: Devanand Sarkar; Zao-Zhong Su; Irina Lebedeva; Moira Sauane; Rahul V Gopalkrishnan; Kristoffer Valerie; Paul Dent; Paul B Fisher
mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):10054-9.
2002: Zao-Zhong Su; Rahul V Gopalkrishnan; Gopeshwar Narayan; Paul Dent; Paul B Fisher
Progression elevated gene-3, PEG-3, induces genomic instability in rodent and human tumor cells.
Journal of cellular physiology 2002;192(1):34-44.
2002: Liang Qiao; Robert McKinstry; Seema Gupta; Donna Gilfor; Jolene J Windle; Phillip B Hylemon; Steven Grant; Paul B Fisher; Paul Dent
Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53.
Hepatology (Baltimore, Md.) 2002;36(1):39-48.
2002: Zao-Zhong Su; Dong-Chul Kang; Yinming Chen; Olga Pekarskaya; Wei Chao; David J Volsky; Paul B Fisher
Identification and cloning of human astrocyte genes displaying elevated expression after infection with HIV-1 or exposure to HIV-1 envelope glycoprotein by rapid subtraction hybridization, RaSH.
Oncogene 2002;21(22):3592-602.
2002: Liang Qiao; Adly Yacoub; Robert McKinstry; Jong Sung Park; Ruben Caron; Paul B Fisher; Michael P Hagan; Steven Grant; Paul Dent
Pharmocologic inhibitors of the mitogen activated protein kinase cascade have the potential to interact with ionizing radiation exposure to induce cell death in carcinoma cells by multiple mechanisms.
Cancer biology & therapy 2002;1(2):168-76.
2002: Irina Lebedeva; Zao-Zhong Su; Yonmee Chang; Shinichi Kitada; John C Reed; Paul B Fisher
The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells.
Oncogene 2002;21(5):708-18.
2002: Dong-Chul Kang; Rahul V Gopalkrishnan; Qingping Wu; Eckhard Jankowsky; Anna Marie Pyle; Paul B Fisher
mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):637-42.
2002: Steven Grant; Paul B Fisher; Paul Dent
The role of signal transduction pathways in drug and radiation resistance.
Cancer treatment and research 2002;112():89-108.
2001: Rahul V Gopalkrishnan; Dong-Chul Kang; Paul B Fisher
Molecular markers and determinants of prostate cancer metastasis.
Journal of cellular physiology 2001;189(3):245-56.
2001: Liang Qiao; K Leach; Robert McKinstry; Donna Gilfor; Adly Yacoub; Jong Sung Park; Steven Grant; Phillip B Hylemon; Paul B Fisher; Paul Dent
Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression.
Hepatology (Baltimore, Md.) 2001;34(5):906-17.
2001: E Y Huang; MT Madireddi; Rahul V Gopalkrishnan; Magdalena Leszczyniecka; Zhaozhong Su; Irina Lebedeva; D Kang; Hong Jiang; JJ Lin; D Alexandre; Yinming Chen; Nicolaq Vozhilla; M X Mei; KA Christiansen; F Sivo; NI Goldstein; A B Mhashilkar; S Chada; E Huberman; Sidney Pestka; Paul B Fisher
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
Oncogene 2001;20(48):7051-63.
2001: Liang Qiao; Elaine Studer; K Leach; Robert McKinstry; Seema Gupta; Roy H Decker; R Kukreja; Kristoffer Valerie; Prakash S Nagarkatti; Wafik S El-Deiry; J Molkentin; Rupert K Schmidt-Ullrich; Paul B Fisher; Steven Grant; Phillip B Hylemon; Paul Dent
Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
Molecular biology of the cell 2001;12(9):2629-45.
2001: Zhaozhong Su; Irina Lebedeva; Rahul V Gopalkrishnan; NI Goldstein; Cy A Stein; J C Reed; Paul Dent; Paul B Fisher
A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10332-7.
2001: Roberto R Rosato; Zhiliang Wang; Rahul V Gopalkrishnan; Paul B Fisher; Steven Grant
Evidence of a functional role for the cyclin-dependent kinase-inhibitor p21WAF1/CIP1/MDA6 in promoting differentiation and preventing mitochondrial dysfunction and apoptosis induced by sodium butyrate in human myelomonocytic leukemia cells (U937).
International journal of oncology 2001;19(1):181-91.
2001: Jong Sung Park; Liang Qiao; Zao-Zhong Su; Darin Hinman; Karen A Willoughby; Robert McKinstry; Adly Yacoub; Gregory J Duigou; C S H Young; Steven Grant; Michael P Hagan; E Ellis; Paul B Fisher; Paul Dent
Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways.
Oncogene 2001;20(25):3266-80.
2001: Malgorzata Simm; Z Su; E Y Huang; Yinming Chen; Hong Jiang; David J Volsky; Paul B Fisher
Cloning of differentially expressed genes in an HIV-1 resistant T cell clone by rapid subtraction hybridization, RaSH.
Gene 2001;269(1-2):93-101.
2001: Magdalena Leszczyniecka; T Roberts; Paul Dent; Steven Grant; Paul B Fisher
Differentiation therapy of human cancer: basic science and clinical applications.
Pharmacology & therapeutics 2001;90(2-3):105-56.
2001: D Kang; Hong Jiang; Q Wu; S Pestka; Paul B Fisher
Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH.
Gene 2001;267(2):233-42.
2001: Z Su; Y Shi; R Friedman; L Qiao; R McKinstry; Darin Hinman; Paul Dent; Paul B Fisher
PEA3 sites within the progression elevated gene-3 (PEG-3) promoter and mitogen-activated protein kinase contribute to differential PEG-3 expression in Ha-ras and v-raf oncogene transformed rat embryo cells.
Nucleic acids research 2001;29(8):1661-71.
2000: Hong Jiang; Dong-Chul Kang; D Alexandre; Paul B Fisher
RaSH, a rapid subtraction hybridization approach for identifying and cloning differentially expressed genes.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12684-9.
2000: MT Madireddi; Paul Dent; Paul B Fisher
AP-1 and C/EBP transcription factors contribute to mda-7 gene promoter activity during human melanoma differentiation.
Journal of cellular physiology 2000;185(1):36-46.
2000: Rahul V Gopalkrishnan; T Roberts; S Tuli; D Kang; KA Christiansen; Paul B Fisher
Molecular characterization of prostate carcinoma tumor antigen-1, PCTA-1, a human galectin-8 related gene.
Oncogene 2000;19(38):4405-16.
2000: Jong Sung Park; Liang Qiao; Donna Gilfor; M Y Yang; Phillip B Hylemon; C Benz; G Darlington; G Firestone; Paul B Fisher; Paul Dent
A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes.
Molecular biology of the cell 2000;11(9):2915-32.
2000: Zhiliang Wang; Shujie Wang; Paul B Fisher; Paul Dent; Steven Grant
Evidence of a functional role for the cyclin-dependent kinase inhibitor p21CIP1 in leukemic cell (U937) differentiation induced by low concentrations of 1-beta-D-arabinofuranosylcytosine.
Differentiation; research in biological diversity 2000;66(1):1-13.
2000: Zhaozhong Su; Y Shi; Paul B Fisher
Cooperation between AP1 and PEA3 sites within the progression elevated gene-3 (PEG-3) promoter regulate basal and differential expression of PEG-3 during progression of the oncogenic phenotype in transformed rat embryo cells.
Oncogene 2000;19(30):3411-21.
2000: MT Madireddi; Paul Dent; Paul B Fisher
Regulation of mda-7 gene expression during human melanoma differentiation.
Oncogene 2000;19(10):1362-8.
2000: Leanne Cartee; Julie Vrana; Zhiliang Wang; Jong Sung Park; Michael J Birrer; Paul B Fisher; Steven Grant; Paul Dent
Inhibition of the mitogen activated protein kinase pathway potentiates radiation-induced cell killing via cell cycle arrest at the G2/M transition and independently of increased signaling by the JNK/c-Jun pathway.
International journal of oncology 2000;16(2):413-22.
2000: Jong Sung Park; S Boyer; K Mitchell; Donna Gilfor; Michael J Birrer; G Darlington; Wafik S El-Deiry; G L Firestone; K Munger; V Band; Paul B Fisher; Paul Dent
Expression of human papilloma virus E7 protein causes apoptosis and inhibits DNA synthesis in primary hepatocytes via increased expression of p21(Cip-1/WAF1/MDA6).
The Journal of biological chemistry 2000;275(1):18-28.
2000: MT Madireddi; Zao-Zhong Su; C S H Young; NI Goldstein; Paul B Fisher
Mda-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy.
Advances in experimental medicine and biology 2000;465():239-61.
1999: Zao-Zhong Su; NI Goldstein; Hong Jiang; M N Wang; Gregory J Duigou; C S H Young; Paul B Fisher
PEG-3, a nontransforming cancer progression gene, is a positive regulator of cancer aggressiveness and angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15115-20.
1999: Rahul V Gopalkrishnan; KA Christiansen; NI Goldstein; Ronald A DePinho; Paul B Fisher
Use of the human EF-1alpha promoter for expression can significantly increase success in establishing stable cell lines with consistent expression: a study using the tetracycline-inducible system in human cancer cells.
Nucleic acids research 1999;27(24):4775-82.
1999: Jong Sung Park; S Carter; DB Reardon; Rupert K Schmidt-Ullrich; Paul Dent; Paul B Fisher
Roles for basal and stimulated p21(Cip-1/WAF1/MDA6) expression and mitogen-activated protein kinase signaling in radiation-induced cell cycle checkpoint control in carcinoma cells.
Molecular biology of the cell 1999;10(12):4231-46.
1999: Julie Vrana; Roy H Decker; Charlene R Johnson; Zhiliang Wang; W David Jarvis; V M Richon; M Ehinger; Paul B Fisher; Steven Grant
Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53.
Oncogene 1999;18(50):7016-25.
1999: Zhiliang Wang; GC Van Tuyle; Daniel Conrad; Paul B Fisher; Paul Dent; Steven Grant
Dysregulation of the cyclin-dependent kinase inhibitor p21WAF1/CIP1/MDA6 increases the susceptibility of human leukemia cells (U937) to 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial dysfunction and apoptosis.
Cancer research 1999;59(6):1259-67.
1999: Rahul V Gopalkrishnan; Zao-Zhong Su; NI Goldstein; Paul B Fisher
Translational infidelity and human cancer: role of the PTI-1 oncogene.
The international journal of biochemistry & cell biology 1999;31(1):151-62.
1998: KL Auer; Jong Sung Park; P Seth; R J Coffey; G Darlington; A Abo; M McMahon; Ronald A DePinho; Paul B Fisher; Paul Dent
Prolonged activation of the mitogen-activated protein kinase pathway promotes DNA synthesis in primary hepatocytes from p21Cip-1/WAF1-null mice, but not in hepatocytes from p16INK4a-null mice.
The Biochemical journal 1998;336 ( Pt 3)():551-60.
1998: Paul Dent; W D Jarvis; Michael J Birrer; Paul B Fisher; R K Schmidt-Ullrich; Steven Grant
The roles of signaling by the p42/p44 mitogen-activated protein (MAP) kinase pathway; a potential route to radio- and chemo-sensitization of tumor cells resulting in the induction of apoptosis and loss of clonogenicity.
Leukemia 1998;12(12):1843-50.
1998: Dong-Chul Kang; M Motwani; Paul B Fisher
Role of the transcription factor AP-1 in melanoma differentiation (review).
International journal of oncology 1998;13(6):1117-26.
1998: Zao-Zhong Su; MT Madireddi; JJ Lin; C S H Young; S Kitada; J C Reed; NI Goldstein; Paul B Fisher
The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14400-5.
1998: Dong-Chul Kang; R LaFrance; Zao-Zhong Su; Paul B Fisher
Reciprocal subtraction differential RNA display: an efficient and rapid procedure for isolating differentially expressed gene sequences.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13788-93.
1998: Zhiliang Wang; Z Z Su; Paul B Fisher; Shujie Wang; G VanTuyle; Steven Grant
Evidence of a functional role for the cyclin-dependent kinase inhibitor p21(WAF1/CIP1/MDA6) in the reciprocal regulation of PKC activator-induced apoptosis and differentation in human myelomonocytic leukemia cells.
Experimental cell research 1998;244(1):105-16.
1998: KL Auer; MS Spector; Robert M Tombes; Prem Seth; Paul B Fisher; Bin Gao; Paul Dent; George Kunos
Alpha-adrenergic inhibition of proliferation in HepG2 cells stably transfected with the alpha1B-adrenergic receptor through a p42MAPkinase/p21Cip1/WAF1-dependent pathway.
FEBS letters 1998;436(1):131-8.
1998: S Carter; KL Auer; DB Reardon; Michael J Birrer; Paul B Fisher; Kristoffer Valerie; Rupert K Schmidt-Ullrich; Ross B Mikkelsen; Paul Dent
Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells.
Oncogene 1998;16(21):2787-96.
1998: Paul B Fisher
Prostate Cancer--CHI Conference. Advances in understanding diagnostics and therapy.
IDrugs : the investigational drugs journal 1998;1(1):63-6.
1998: Zhaozhong Su; NI Goldstein; Paul B Fisher
Antisense inhibition of the PTI-1 oncogene reverses cancer phenotypes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1764-9.
1998: JJ Lin; Hong Jiang; Paul B Fisher
Melanoma differentiation associated gene-9, mda-9, is a human gamma interferon responsive gene.
Gene 1998;207(2):105-10.
1998: Srikumar Chellappan; Antonio Giordano; Paul B Fisher
Role of cyclin-dependent kinases and their inhibitors in cellular differentiation and development.
Current topics in microbiology and immunology 1998;227():57-103.
1997: Zao-Zhong Su; Y Shi; Paul B Fisher
Subtraction hybridization identifies a transformation progression-associated gene PEG-3 with sequence homology to a growth arrest and DNA damage-inducible gene.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(17):9125-30.
1997: AJ Freemerman; Julie Vrana; Robert M Tombes; H Jiang; Srikumar Chellappan; Paul B Fisher; Steven Grant
Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the induction of differentiation and drug-mediated apoptosis in human myeloid leukemia cells (HL-60).
Leukemia 1997;11(4):504-13.
1997: Hong Jiang; JJ Lin; J Tao; Paul B Fisher
Suppression of human ribosomal protein L23A expression during cell growth inhibition by interferon-beta.
Oncogene 1997;14(4):473-80.
1997: Y Sun; J Lin; Aaron E Katz; Paul B Fisher
Human prostatic carcinoma oncogene PTI-1 is expressed in human tumor cell lines and prostate carcinoma patient blood samples.
Cancer research 1997;57(1):18-23.
1996: Hong Jiang; Zao-Zhong Su; JJ Lin; NI Goldstein; C S H Young; Paul B Fisher
The melanoma differentiation associated gene mda-7 suppresses cancer cell growth.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9160-5.
1996: Zao-Zhong Su; J Lin; R Shen; Peter E Fisher; NI Goldstein; Paul B Fisher
Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7252-7.
1995: H Jiang; JJ Lin; Zao-Zhong Su; NI Goldstein; Paul B Fisher
Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression.
Oncogene 1995;11(12):2477-86.
1995: H Jiang; J Lin; S M Young; NI Goldstein; S Waxman; Viviana Davila; Srikumar Chellappan; Paul B Fisher
Cell cycle gene expression and E2F transcription factor complexes in human melanoma cells induced to terminally differentiate.
Oncogene 1995;11(6):1179-89.
1995: Zao-Zhong Su; J Lin; Marie Prewett; NI Goldstein; Paul B Fisher
Apoptosis mediates the selective toxicity of caffeic acid phenethyl ester (CAPE) toward oncogene-transformed rat embryo fibroblast cells.
Anticancer research 1995;15(5B):1841-8.
1995: R Shen; Zao-Zhong Su; Carl A Olsson; Paul B Fisher
Identification of the human prostatic carcinoma oncogene PTI-1 by rapid expression cloning and differential RNA display.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(15):6778-82.
1995: Zao-Zhong Su; S Yemul; Cy A Stein; Paul B Fisher
c-fos is a positive regulator of carcinogen enhancement of adenovirus transformation.
Oncogene 1995;10(10):2037-49.
1995: H Jiang; J Lin; Zao-Zhong Su; M Herlyn; R S Kerbel; Bernard E Weissman; Danny R Welch; Paul B Fisher
The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells.
Oncogene 1995;10(9):1855-64.
1994: H Jiang; J Lin; Zao-Zhong Su; F R Collart; E Huberman; Paul B Fisher
Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53.
Oncogene 1994;9(11):3397-406.
1994: Zao-Zhong Su; J Lin; D Grunberger; Paul B Fisher
Growth suppression and toxicity induced by caffeic acid phenethyl ester (CAPE) in type 5 adenovirus-transformed rat embryo cells correlate directly with transformation progression.
Cancer research 1994;54(7):1865-70.
1994: Zao-Zhong Su; R Shen; C A O'Brian; Paul B Fisher
Induction of transformation progression in type 5 adenovirus-transformed rat embryo cells by a cloned protein kinase C beta 1 gene and reversal of progression by 5-azacytidine.
Oncogene 1994;9(4):1123-32.
1994: R Shen; Zao-Zhong Su; Carl A Olsson; NI Goldstein; Paul B Fisher
Surface-epitope masking: a strategy for the development of monoclonal antibodies specific for molecules expressed on the cell surface.
Journal of the National Cancer Institute 1994;86(2):91-8.
1994: J A Leon; NI Goldstein; Paul B Fisher
New approaches for the development and application of monoclonal antibodies for the diagnosis and therapy of human cancer.
Pharmacology & therapeutics 1994;61(1-2):237-78.
1993: Zao-Zhong Su; V N Austin; Stephen G Zimmer; Paul B Fisher
Defining the critical gene expression changes associated with expression and suppression of the tumorigenic and metastatic phenotype in Ha-ras-transformed cloned rat embryo fibroblast cells.
Oncogene 1993;8(5):1211-9.
1993: Zao-Zhong Su; J A Leon; H Jiang; V N Austin; Stephen G Zimmer; Paul B Fisher
Wild-type adenovirus type 5 transforming genes function as transdominant suppressors of oncogenesis in mutant adenovirus type 5 transformed rat embryo fibroblast cells.
Cancer research 1993;53(8):1929-38.
1993: Zao-Zhong Su; R Shen; C S H Young; Paul B Fisher
Genetic analysis of carcinogen enhancement of type 5 adenovirus transformation of cloned Fischer rat embryo fibroblast cells.
Molecular carcinogenesis 1993;8(3):155-66.
1992: Ludovico Guarini; Zao-Zhong Su; S Zucker; J Lin; D Grunberger; Paul B Fisher
Growth inhibition and modulation of antigenic phenotype in human melanoma and glioblastoma multiforme cells by caffeic acid phenethyl ester (CAPE)
Cellular and molecular biology 1992;38(5):513-27.
1992: Thomas Moulton; H Jiang; Ludovico Guarini; Michael R Fetell; Paul B Fisher
Induction of growth suppression and modification of gene expression in multi-drug-resistant human glioblastoma multiforme cells by recombinant human fibroblast and immune interferon.
International journal of cancer. Journal international du cancer 1992;51(3):373-8.
1992: Zao-Zhong Su; Carl A Olsson; Stephen G Zimmer; Paul B Fisher
Transfer of a dominant-acting tumor-inducing oncogene from human prostatic carcinoma cells to cloned rat embryo fibroblast cells by DNA-transfection.
Anticancer research 1992;12(2):297-304.
1992: Zao-Zhong Su; C A O'Brian; Paul B Fisher
Alterations in cellular phenotype induced by the type 5 adenovirus E1A and the beta 1 protein kinase C genes in cloned rat embryo fibroblast cells.
Cellular and molecular biology 1992;38(1):27-39.
1992: J F Boylan; T Y Shih; Paul B Fisher; Stephen G Zimmer
Induction and progression of the transformed phenotype in cloned rat embryo fibroblast cells: studies employing type 5 adenovirus and wild-type and mutant Ha-ras oncogenes.
Molecular carcinogenesis 1992;5(2):118-28.
1992: Ludovico Guarini; G M Graham; H Jiang; S Ferrone; S Zucker; Paul B Fisher
Modulation of the antigenic phenotype of human melanoma cells by differentiation-inducing and growth-suppressing agents.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1992;Suppl 2():123-31.
1992: J A Leon; M C Gutierrez; H Jiang; Alison Estabrook; S Waxman; Paul B Fisher
Modulation of the antigenic phenotype of human breast carcinoma cells by modifiers of protein kinase C activity and recombinant human interferons.
Cancer immunology, immunotherapy : CII 1992;35(5):315-24.
1991: G J Duigou; Zao-Zhong Su; L E Babiss; B Driscoll; Yuen-Kai Fung; Paul B Fisher
Analysis of viral and cellular gene expression during progression and suppression of the transformed phenotype in type 5 adenovirus-transformed rat embryo cells.
Oncogene 1991;6(10):1813-24.
1991: P G Reddy; G M Graham; S Datta; Ludovico Guarini; Thomas Moulton; H P Jiang; Michael M Gottesman; S Ferrone; Paul B Fisher
Effect of recombinant fibroblast interferon and recombinant immune interferon on growth and the antigenic phenotype of multidrug-resistant human glioblastoma multiforme cells.
Journal of the National Cancer Institute 1991;83(18):1307-15.
1991: Zao-Zhong Su; G J Duigou; Paul B Fisher
Low-level beta 1 protein kinase C expression in cloned rat embryo fibroblast cells enhances transformation induced by the adenovirus type 5 E1A gene.
Molecular carcinogenesis 1991;4(4):328-37.
1991: Zao-Zhong Su; D Grunberger; Paul B Fisher
Suppression of adenovirus type 5 E1A-mediated transformation and expression of the transformed phenotype by caffeic acid phenethyl ester (CAPE).
Molecular carcinogenesis 1991;4(3):231-42.
1991: G M Graham; Ludovico Guarini; Thomas Moulton; S Datta; S Ferrone; P Giacomini; R S Kerbel; Paul B Fisher
Potentiation of growth suppression and modulation of the antigenic phenotype in human melanoma cells by the combination of recombinant human fibroblast and immune interferons.
Cancer immunology, immunotherapy : CII 1991;32(6):382-90.
1990: Ludovico Guarini; M Temponi; Jeffrey N Bruce; A P Bollon; G J Duigou; Thomas Moulton; S Ferrone; Paul B Fisher
Expression and modulation by cytokines of the intercellular adhesion molecule-1 (ICAM-1) in human central nervous system tumor cell cultures.
International journal of cancer. Journal international du cancer 1990;46(6):1041-7.
1990: W E Solowey; Sidney Pestka; S Spector; R I Fryer; Paul B Fisher
Peripheral-acting benzodiazepines inhibit the growth of human melanoma cells and potentiate the antiproliferative activity of recombinant human interferons.
Journal of interferon research 1990;10(3):269-80.
1990: J F Boylan; J Jackson; Marion R Steiner; T Y Shih; G J Duigou; T Roszman; Paul B Fisher; Stephen G Zimmer
Role of the Ha-ras (RasH) oncogene in mediating progression of the tumor cell phenotype (review).
Anticancer research 1990;10(3):717-24.
1990: G J Duigou; L E Babiss; D S Iman; J W Shay; Paul B Fisher
Suppression of the progression phenotype in somatic cell hybrids occurs in the absence of altered adenovirus type 5 gene expression.
Molecular and cellular biology 1990;10(5):2027-34.
1990: Michael R Fetell; E M Housepian; M W Oster; D N Cote; Michael B Sisti; S G Marcus; Paul B Fisher
Intratumor administration of beta-interferon in recurrent malignant gliomas. A phase I clinical and laboratory study.
Cancer 1990;65(1):78-83.
1990: Zao-Zhong Su; P Q Zhang; C Geard; Paul B Fisher
Enhancement of adenovirus transformation of cloned rat embryo fibroblast cells by gamma irradiation.
Molecular carcinogenesis 1990;3(3):141-9.
1990: Zao-Zhong Su; P Q Zhang; Paul B Fisher
Enhancement of viral and DNA mediated transformation of cloned rat embryo fibroblast cells by 3-aminobenzamide.
Molecular carcinogenesis 1990;3(5):309-18.
1990: Duane L Guernsey; Paul B Fisher
Thyroid hormone and neoplastic transformation.
Critical reviews in oncogenesis 1990;1(4):389-408.
1989: J A Leon; R Mesa-Tejada; M C Gutierrez; Alison Estabrook; J W Greiner; J Schlom; Paul B Fisher
Increased surface expression and shedding of tumor associated antigens by human breast carcinoma cells treated with recombinant human interferons or phorbol ester tumor promoters.
Anticancer research 1989;9(6):1639-47.
1989: Ludovico Guarini; M Temponi; G M Edwalds; J R Vita; Paul B Fisher; S Ferrone
In vitro differentiation and antigenic changes in human melanoma cell lines.
Cancer immunology, immunotherapy : CII 1989;30(5):262-8.
1989: Zao-Zhong Su; Paul B Fisher
Early events in methyl methanesulfonate enhancement of adenovirus transformation of cloned rat embryo fibroblast cells.
Molecular carcinogenesis 1989;2(5):252-60.
1988: R S Herbst; H Hermo; Paul B Fisher; L E Babiss
Regulation of adenovirus and cellular gene expression and of cellular transformation by the E1B-encoded 175-amino-acid protein.
Journal of virology 1988;62(12):4634-43.
1988: H Hermo; G J Duigou; Stephen G Zimmer; Paul B Fisher
Effect of methyl methanesulfonate on type 5 adenovirus DNA integration and the phenotypic properties of cold-sensitive type 5 adenovirus-transformed cloned rat embryo fibroblast cells.
Cancer research 1988;48(11):3050-7.
1988: J R Vita; G M Edwalds; T Gorey; E M Housepian; Michael R Fetell; Ludovico Guarini; J A Langer; Paul B Fisher
Enhanced in vitro growth suppression of human glioblastoma cultures treated with the combination of recombinant fibroblast and immune interferons.
Anticancer research 1988;8(3):297-302.
1988: Armand F Miranda; G J Duigou; E Hernandez; Paul B Fisher
Characterization of mutant human fibroblast cultures transformed with simian virus 40.
Journal of cell science 1988;89 ( Pt 4)():481-93.
1987: Duane L Guernsey; G J Duigou; L E Babiss; Paul B Fisher
Regulation of thyroidal inducibility of Na,K-ATPase and binding of epidermal growth factor in wild-type and cold-sensitive E1a mutant type 5 adenovirus-transformed CREF cells.
Journal of cellular physiology 1987;133(3):507-14.
1987: H Hermo; G J Duigou; L E Babiss; Paul B Fisher
Unique carcinogen enhancement of transformation phenotype displayed by cloned rat embryo fibroblast (CREF) cells treated with methyl methanesulfonate and infected with a specific host-range mutant of type 5 adenovirus.
Carcinogenesis 1987;8(7):967-75.
1987: G J Duigou; L E Babiss; W S Liaw; Stephen G Zimmer; H S Ginsberg; Paul B Fisher
Mutations in the E1a gene of type 5 adenovirus result in oncogenic transformation of Fischer rat embryo cells.
Journal of cellular biochemistry 1987;33(2):117-26.
1986: Paul B Fisher; H Hermo; W E Solowey; M C Dietrich; G M Edwalds; I B Weinstein; J A Langer; S Pestka; P Giacomini; M Kusama
Effect of recombinant human fibroblast interferon and mezerein on growth, differentiation, immune interferon binding and tumor associated antigen expression in human melanoma cells.
Anticancer research 1986;6(4):765-74.
1986: L E Babiss; W S Liaw; Stephen G Zimmer; G C Godman; H S Ginsberg; Paul B Fisher
Mutations in the E1a gene of adenovirus type 5 alter the tumorigenic properties of transformed cloned rat embryo fibroblast cells.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(7):2167-71.
1985: L E Babiss; Duane L Guernsey; Paul B Fisher
Regulation of anchorage-independent growth by thyroid hormone in type 5 adenovirus-transformed rat embryo cells.
Cancer research 1985;45(12 Pt 1):6017-23.
1985: H Hermo; L E Babiss; W S Liaw; I M Pinto; R J McDonald; Paul B Fisher
Chemical-viral interactions in cell transformation: enhancement of human adenovirus transformation of cloned rat embryo fibroblast (CREF) cells by alkylating carcinogens.
Progress in clinical and biological research 1985;172A():489-512.
1985: J W Greiner; J Schlom; S Pestka; J A Langer; P Giacomini; M Kusama; S Ferrone; Paul B Fisher
Modulation of tumor associated antigen expression and shedding by recombinant human leukocyte and fibroblast interferons.
Pharmacology & therapeutics 1985;31(3):209-36.
1984: L E Babiss; Paul B Fisher; H S Ginsberg
Effect on transformation of mutations in the early region 1b-encoded 21- and 55-kilodalton proteins of adenovirus 5.
Journal of virology 1984;52(2):389-95.
1984: L E Babiss; Paul B Fisher; H S Ginsberg
Deletion and insertion mutations in early region 1a of type 5 adenovirus that produce cold-sensitive or defective phenotypes for transformation.
Journal of virology 1984;49(3):731-40.
1983: L E Babiss; C S H Young; Paul B Fisher; H S Ginsberg
Expression of adenovirus E1a and E1b gene products and the Escherichia coli XGPRT gene in KB cells.
Journal of virology 1983;46(2):454-65.
1983: L E Babiss; H S Ginsberg; Paul B Fisher
Cold-sensitive expression of transformation by a host range mutant of type 5 adenovirus.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(5):1352-6.
1982: Paul B Fisher; L E Babiss; I B Weinstein; H S Ginsberg
Analysis of type 5 adenovirus transformation with a cloned rat embryo cell line (CREF).
Proceedings of the National Academy of Sciences of the United States of America 1982;79(11):3527-31.
1981: Paul B Fisher; C S H Young; I Bernard Weinstein; T H Carter
Tumor promoters alter the temporal program of adenovirus replication in human cells.
Molecular and cellular biology 1981;1(4):370-80.