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Ignacio Fita

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X Ray Crystallography

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TOP 3
David Aparicio; Xavier Carpena; Mireia Díaz; Joan C Ferrer; Peter C Loewen; Rosa Pérez-Luque; Ignacio Fita
Structural Asymmetry and Disulfide Bridges among Subunits Modulate the Activity of Human Malonyl-CoA Decarboxylase.
Peter C Loewen; Rosa Perez-Luque; Jack Switala; Allison L Didychuk; Ignacio Fita; Michele C Loewen
Structure of Pisum sativum Rubisco with bound ribulose 1,5-bisphosphate.
Bárbara M Calisto; Luca Martinelli; Jaume Piñol; Enrique Querol; Alícia Broto; Ignacio Fita
The EAGR box structure: a motif involved in mycoplasma motility.

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2013: David Aparicio; Xavier Carpena; Mireia Díaz; Joan C Ferrer; Peter C Loewen; Rosa Pérez-Luque; Ignacio Fita
Structural Asymmetry and Disulfide Bridges among Subunits Modulate the Activity of Human Malonyl-CoA Decarboxylase.
The Journal of biological chemistry 2013;288(17):11907-19.
2013: Peter C Loewen; Rosa Perez-Luque; Jack Switala; Allison L Didychuk; Ignacio Fita; Michele C Loewen
Structure of Pisum sativum Rubisco with bound ribulose 1,5-bisphosphate.
Acta crystallographica. Section F, Structural biology and crystallization communications 2013;69(Pt 1):10-4.
2012: Bárbara M Calisto; Luca Martinelli; Jaume Piñol; Enrique Querol; Alícia Broto; Ignacio Fita
The EAGR box structure: a motif involved in mycoplasma motility.
Molecular microbiology 2012;86(2):382-93.
2012: Vikash Jha; Xavier Carpena; Prashen Chelikani; Ignacio Fita; Peter C Loewen
Influence of main channel structure on H(2)O(2) access to the heme cavity of catalase KatE of Escherichia coli.
Archives of biochemistry and biophysics 2012;526(1):54-9.
2012: Adelaida Díaz; Ignacio Fita; Peter C Loewen; Xavier Carpena
Thirty years of heme catalases structural biology.
Archives of biochemistry and biophysics 2012;525(2):102-10.
2012: Sergio De Cima; Ignacio Fita; Fernando Gil-Ortiz; Marjolaine Crabeel; Vicente Rubio
Insight on an arginine synthesis metabolon from the tetrameric structure of yeast acetylglutamate kinase.
PloS one 2012;7(4):e34734.
2011: Vikash Jha; Sherif Louis; Prashen Chelikani; Xavier Carpena; Lynda J Donald; Ignacio Fita; Peter C Loewen
Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli.
Biochemistry 2011;50(12):2101-10.
2011: Trevor Addington; Barbara Calisto; Mercedes Alfonso-Prieto; Carme Rovira; Ignacio Fita; Antoni Planas
Re-engineering specificity in 1,3-1, 4-β-glucanase to accept branched xyloglucan substrates.
Proteins 2011;79(2):365-75.
2010: Pietro Vidossich; Mercedes Alfonso-Prieto; Xavi Carpena; Ignacio Fita; Peter C Loewen; Carme Rovira
The dynamic role of distal side residues in heme hydroperoxidase catalysis. Interplay between X-ray crystallography and ab initio MD simulations.
Archives of biochemistry and biophysics 2010;500(1):37-44.
2010: Fernando Gil-Ortiz; Santiago Ramón-Maiques; María L Fernández-Murga; Ignacio Fita; Vicente Rubio
Two crystal structures of Escherichia coli N-acetyl-L-glutamate kinase demonstrate the cycling between open and closed conformations.
Journal of molecular biology 2010;399(3):476-90.
2010: Santiago Ramón-Maiques; Alberto Marina; Anna Guinot; Fernando Gil-Ortiz; Matxalen Uriarte; Ignacio Fita; Vicente Rubio
Substrate binding and catalysis in carbamate kinase ascertained by crystallographic and site-directed mutagenesis studies: movements and significance of a unique globular subdomain of this key enzyme for fermentative ATP production in bacteria.
Journal of molecular biology 2010;397(5):1261-75.
2009: Jordi Querol-Audí; Arnau Casañas; Isabel Usón; Daniel Luque; José R Castón; Ignacio Fita; Jose Caston
The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP.
The EMBO journal 2009;28(21):3450-7.
2009: Xavier Carpena; Pietro Vidossich; Klarissa Schroettner; Barbara M Calisto; Srijib Banerjee; Johanna Stampler; Monika Soudi; Paul G Furtmüller; Carme Rovira; Ignacio Fita; Christian Obinger
Essential role of proximal histidine-asparagine interaction in mammalian peroxidases.
The Journal of biological chemistry 2009;284(38):25929-37.
2009: Sergio Porté; Eva Valencia; Evgenia A Yakovtseva; Emma Borràs; Naeem Shafqat; Judit E Debreczeny; Ashley C W Pike; Udo Oppermann; Jaume Farrés; Ignacio Fita; Xavier Parés
Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3.
The Journal of biological chemistry 2009;284(25):17194-205.
2009: Marta Guerrero; Cristina Ferrer-Orta; Jordi Querol-Audí; Consuelo Marin-Vicente; Ignacio Fita; Juan C Gómez-Fernández; Nuria Verdaguer; Senena Corbalan-Garcia
Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(16):6603-7.
2009: F Xavier Ruiz; Oriol Gallego; Albert Ardèvol; Armando Moro; Marta Domínguez; Susana Alvarez; Rosana Alvarez; Angel R de Lera; Concepció Rovira; Ignacio Fita; Xavier Parés; Jaume Farrés
Aldo-keto reductases from the AKR1B subfamily: retinoid specificity and control of cellular retinoic acid levels.
Chemico-biological interactions 2009;178(1-3):171-7.
2009: Jordi Querol-Audí; Tuende Konecsni; joan pous; Oliviero Carugo; Ignacio Fita; Nuria Verdaguer; Dieter Blaas
Minor group human rhinovirus-receptor interactions: geometry of multimodular attachment and basis of recognition.
FEBS letters 2009;583(1):235-40.
2008: Mercedes Alfonso-Prieto; Pietro Vidossich; Antonio Rodríguez-Fortea; Xavi Carpena; Ignacio Fita; Peter C Loewen; Concepció Rovira
Electronic state of the molecular oxygen released by catalase.
The journal of physical chemistry. A 2008;112(50):12842-8.
2008: José L Llácer; Ignacio Fita; Vicente Rubio
Arginine and nitrogen storage.
Current opinion in structural biology 2008;18(6):673-81.
2008: Marina Brucet; Jordi Querol-Audí; Kamila Bertlik; Jorge Lloberas; Ignacio Fita; Antonio Celada
Structural and biochemical studies of TREX1 inhibition by metals. Identification of a new active histidine conserved in DEDDh exonucleases.
Protein science : a publication of the Protein Society 2008;17(12):2059-69.
2007: Oriol Gallego; F Xavier Ruiz; Albert Ardèvol; Marta Domínguez; Rosana Alvarez; Angel R de Lera; Concepció Rovira; Jaume Farrés; Ignacio Fita; Xavier Parés
Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(52):20764-9.
2007: Pietro Vidossich; Mercedes Alfonso-Prieto; Xavier Carpena; Peter C Loewen; Ignacio Fita; Carme Rovira
Versatility of the electronic structure of compound I in catalase-peroxidases.
Journal of the American Chemical Society 2007;129(44):13436-46.
2007: José L Llácer; Asunción Contreras; Karl Forchhammer; Clara Marco-Marín; Fernando Gil-Ortiz; Rafael Maldonado; Ignacio Fita; Vicente Rubio
The crystal structure of the complex of PII and acetylglutamate kinase reveals how PII controls the storage of nitrogen as arginine.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(45):17644-9.
2007: Joana Fort; Laura R de la Ballina; Hans E Burghardt; Carles Ferrer-Costa; Javier Turnay; Cristina Ferrer-Orta; Isabel Usón; Antonio Zorzano; Juan Fernandez-Recio; Modesto Orozco; M Antonia Lizarbe; Ignacio Fita; Manuel Palacín
The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane.
The Journal of biological chemistry 2007;282(43):31444-52.
2007: Barbara M Calisto; Jordi Perez-Gil; Maria Bergua; Jordi Querol-Audi; Ignacio Fita; Santiago Imperial
Biosynthesis of isoprenoids in plants: structure of the 2C-methyl-D-erithrytol 2,4-cyclodiphosphate synthase from Arabidopsis thaliana. Comparison with the bacterial enzymes.
Protein science : a publication of the Protein Society 2007;16(9):2082-8.
2007: Marina Brucet; Jordi Querol-Audí; Maria Serra; Ximena Ramirez-Espain; Kamila Bertlik; Lidia Ruiz; Jorge Lloberas; Maria J Macias; Ignacio Fita; Antonio Celada
Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains.
The Journal of biological chemistry 2007;282(19):14547-57.
2007: Clara Marco-Marín; Fernando Gil-Ortiz; isabel pérez-arellano; Javier Cervera; Ignacio Fita; Vicente Rubio
A novel two-domain architecture within the amino acid kinase enzyme family revealed by the crystal structure of Escherichia coli glutamate 5-kinase.
Journal of molecular biology 2007;367(5):1431-46.
2007: Mercedes Alfonso-Prieto; Anton Borovik; Xavier Carpena; Garib Murshudov; William Melik-Adamyan; Ignacio Fita; Carme Rovira; Peter C Loewen
The structures and electronic configuration of compound I intermediates of Helicobacter pylori and Penicillium vitale catalases determined by X-ray crystallography and QM/MM density functional theory calculations.
Journal of the American Chemical Society 2007;129(14):4193-205.
2007: Taweewat Deemagarn; Ben Wiseman; Xavier Carpena; Anabella Ivancich; Ignacio Fita; Peter C Loewen
Two alternative substrate paths for compound I formation and reduction in catalase-peroxidase KatG from Burkholderia pseudomallei.
Proteins 2007;66(1):219-28.
2006: Stefano Trapani; Chantal Abergel; Irina Gutsche; Cristina Horcajada; Ignacio Fita; Jorge Navaza
Combining experimental data for structure determination of flexible multimeric macromolecules by molecular replacement.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 5):467-75.
2006: Xavier Carpena; Ben Wiseman; Taweewat Deemagarn; Beatriz Herguedas; Anabella Ivancich; Rahul Singh; Peter C Loewen; Ignacio Fita
Roles for Arg426 and Trp111 in the modulation of NADH oxidase activity of the catalase-peroxidase KatG from Burkholderia pseudomallei inferred from pH-induced structural changes.
Biochemistry 2006;45(16):5171-9.
2006: Santiago Ramón-Maiques; M Leonor Fernández-Murga; Fernando Gil-Ortiz; Alexei Vagin; Ignacio Fita; Vicente Rubio
Structural bases of feed-back control of arginine biosynthesis, revealed by the structures of two hexameric N-acetylglutamate kinases, from Thermotoga maritima and Pseudomonas aeruginosa.
Journal of molecular biology 2006;356(3):695-713.
2006: Cristina Horcajada; Joan J Guinovart; Ignacio Fita; Juan C Ferrer
Crystal structure of an archaeal glycogen synthase: insights into oligomerization and substrate binding of eukaryotic glycogen synthases.
The Journal of biological chemistry 2006;281(5):2923-31.
2005: Xavier Carpena; Ben Wiseman; Taweewat Deemagarn; Rahul Singh; Jack Switala; Anabella Ivancich; Ignacio Fita; Peter C Loewen
A molecular switch and electronic circuit modulate catalase activity in catalase-peroxidases.
EMBO reports 2005;6(12):1156-62.
2005: Bárbara M Calisto; Oscar Q Pich; Jaume Piñol; Ignacio Fita; Enrique Querol; Xavier Carpena
Crystal structure of a putative type I restriction-modification S subunit from Mycoplasma genitalium.
Journal of molecular biology 2005;351(4):749-62.
2005: Jordi Querol-Audí; Rosa Perez-Luque; Ignacio Fita; Carmen Lopéz-Iglesias; Jose Caston; José L Carrascosa; Nuria Verdaguer
Preliminary analysis of two and three dimensional crystals of vault ribonucleoprotein particles.
Journal of structural biology 2005;151(1):111-5.
2005: Prashen Chelikani; Xavier Carpena; Rosa Perez-Luque; Lynda J Donald; Harry W Duckworth; Jack Switala; Ignacio Fita; Peter C Loewen
Characterization of a large subunit catalase truncated by proteolytic cleavage.
Biochemistry 2005;44(15):5597-605.
2005: Taweewat Deemagarn; Xavier Carpena; Rahul Singh; Ben Wiseman; Ignacio Fita; Peter C Loewen
Structural characterization of the Ser324Thr variant of the catalase-peroxidase (KatG) from Burkholderia pseudomallei.
Journal of molecular biology 2005;345(1):21-8.
2004: Rahul Singh; Ben Wiseman; Taweewat Deemagarn; Lynda J Donald; Harry W Duckworth; Xavier Carpena; Ignacio Fita; Peter C Loewen
Catalase-peroxidases (KatG) exhibit NADH oxidase activity.
The Journal of biological chemistry 2004;279(41):43098-106.
2004: Xavier Carpena; William Melik-Adamyan; Peter C Loewen; Ignacio Fita
Structure of the C-terminal domain of the catalase-peroxidase KatG from Escherichia coli.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 10):1824-32.
2004: Eva Valencia; Carol Larroy; Wendy F Ochoa; Xavier Parés; Ignacio Fita; Josep A Biosca
Apo and Holo structures of an NADPH-dependent cinnamyl alcohol dehydrogenase from Saccharomyces cerevisiae.
Journal of molecular biology 2004;341(4):1049-62.
2004: Nuria Verdaguer; Ignacio Fita; Manuela Reithmayer; Rosita Moser; Dieter Blaas
X-ray structure of a minor group human rhinovirus bound to a fragment of its cellular receptor protein.
Nature structural & molecular biology 2004;11(5):429-34.
2004: Peter C Loewen; Xavier Carpena; Carme Rovira; Anabella Ivancich; Rosa Perez-Luque; Rainer Haas; Stefan Odenbreit; Peter Nicholls; Ignacio Fita
Structure of Helicobacter pylori catalase, with and without formic acid bound, at 1.6 A resolution.
Biochemistry 2004;43(11):3089-103.
2004: Prashen Chelikani; Ignacio Fita; Peter C Loewen
Diversity of structures and properties among catalases.
Cellular and molecular life sciences : CMLS 2004;61(2):192-208.
2003: Anna Rosell; Eva Valencia; Wendy F Ochoa; Ignacio Fita; Xavier Parés; Jaume Farrés
Complete reversal of coenzyme specificity by concerted mutation of three consecutive residues in alcohol dehydrogenase.
The Journal of biological chemistry 2003;278(42):40573-80.
2003: Lynda J Donald; Oleg Krokhin; Harry W Duckworth; Ben Wiseman; Taweewat Deemagarn; Rahul Singh; Jack Switala; Xavier Carpena; Ignacio Fita; Peter C Loewen
Characterization of the catalase-peroxidase KatG from Burkholderia pseudomallei by mass spectrometry.
The Journal of biological chemistry 2003;278(37):35687-92.
2003: Nuria Verdaguer; Miguel A Jimenez-Clavero; Ignacio Fita; Victoria Ley
Structure of swine vesicular disease virus: mapping of changes occurring during adaptation of human coxsackie B5 virus to infect swine.
Journal of virology 2003;77(18):9780-9.
2003: Prashen Chelikani; Xavier Carpena; Ignacio Fita; Peter C Loewen
An electrical potential in the access channel of catalases enhances catalysis.
The Journal of biological chemistry 2003;278(33):31290-6.
2003: Fernando Gil-Ortiz; Santiago Ramón-Maiques; Ignacio Fita; Vicente Rubio
The course of phosphorus in the reaction of N-acetyl-L-glutamate kinase, determined from the structures of crystalline complexes, including a complex with an AlF(4)(-) transition state mimic.
Journal of molecular biology 2003;331(1):231-44.
2003: Wendy F Ochoa; Alejandro Torrecillas; Ignacio Fita; Nuria Verdaguer; Senena Corbalan-Garcia; Juan C Gomez-Fernandez
Retinoic acid binds to the C2-domain of protein kinase C(alpha).
Biochemistry 2003;42(29):8774-9.
2003: Anna Rosell; Eva Valencia; Xavier Parés; Ignacio Fita; Jaume Farrés; Wendy F Ochoa
Crystal structure of the vertebrate NADP(H)-dependent alcohol dehydrogenase (ADH8).
Journal of molecular biology 2003;330(1):75-85.
2003: Xavier Carpena; Suvit Loprasert; skorn Mongkolsuk; Jack Switala; Peter C Loewen; Ignacio Fita
Catalase-peroxidase KatG of Burkholderia pseudomallei at 1.7A resolution.
Journal of molecular biology 2003;327(2):475-89.
2003: Miguel A Jimenez-Clavero; Victoria Ley; Ignacio Fita; Nuria Verdaguer
Crystallization and preliminary X-ray analysis of swine vesicular disease virus (SVDV).
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 3):541-3.
2003: Xavier Carpena; Manuel Soriano; Martin Klotz; Harry W Duckworth; Lynda J Donald; William Melik-Adamyan; Ignacio Fita; Peter C Loewen
Structure of the Clade 1 catalase, CatF of Pseudomonas syringae, at 1.8 A resolution.
Proteins 2003;50(3):423-36.
2003: Eva Valencia; Anna Rosell; Carol Larroy; Jaume Farrés; Josep A Biosca; Ignacio Fita; Xavier Parés; Wendy F Ochoa
Crystallization and preliminary X-ray analysis of NADP(H)-dependent alcohol dehydrogenases from Saccharomyces cerevisiae and Rana perezi.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 2):334-7.
2002: Xavier Carpena; Jack Switala; Suvit Loprasert; skorn Mongkolsuk; Ignacio Fita; Peter C Loewen
Crystallization and preliminary X-ray analysis of the catalase-peroxidase KatG from Burkholderia pseudomallei.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 12):2184-6.
2002: Fernando Gil-Ortiz; Ignacio Fita; Santiago Ramón-Maiques; Alberto Marina; Vicente Rubio
A crystallographic glimpse of a nucleotide triphosphate (AMPPNP) bound to a protein surface: external and internal AMPPNP molecules in crystalline N-acetyl-L-glutamate kinase.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 10 Pt 2):1892-5.
2002: Wendy F Ochoa; Senena Corbalán-Garcia; Ramon Eritja; José A Rodríguez-Alfaro; Juan C Gómez-Fernández; Ignacio Fita; Nuria Verdaguer
Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha.
Journal of molecular biology 2002;320(2):277-91.
2002: M Leonor Fernández-Murga; Santiago Ramón-Maiques; Fernando Gil-Ortiz; Ignacio Fita; Vicente Rubio
Towards structural understanding of feedback control of arginine biosynthesis: cloning and expression of the gene for the arginine-inhibited N-acetyl-L-glutamate kinase from Pseudomonas aeruginosa, purification and crystallization of the recombinant enzyme and preliminary X-ray studies.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 6 Pt 2):1045-7.
2002: Xavier Carpena; Alba Guarné; Juan C Ferrer; Pedro Alzari; Ignacio Fita; Peter C Loewen
Crystallization and preliminary X-ray analysis of the hydroperoxidase I C-terminal domain from Escherichia coli.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 5):853-5.
2002: Santiago Ramón-Maiques; Alberto Marina; Fernando Gil-Ortiz; Ignacio Fita; Vicente Rubio
Structure of acetylglutamate kinase, a key enzyme for arginine biosynthesis and a prototype for the amino acid kinase enzyme family, during catalysis.
Structure (London, England : 1993) 2002;10(3):329-42.
2001: Susana G Kalko; Josep Lluis Gelpí; Ignacio Fita; Modesto Orozco
Theoretical study of the mechanisms of substrate recognition by catalase.
Journal of the American Chemical Society 2001;123(39):9665-72.
2001: Wendy F Ochoa; J Garcia-Garcia; Ignacio Fita; Senena Corbalan-Garcia; Nuria Verdaguer; Juan C Gomez-Fernandez
Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains.
Journal of molecular biology 2001;311(4):837-49.
2001: William Melik-Adamyan; J Bravo; Xavier Carpena; Jack Switala; María J Maté; Ignacio Fita; Peter C Loewen
Substrate flow in catalases deduced from the crystal structures of active site variants of HPII from Escherichia coli.
Proteins 2001;44(3):270-81.
2001: Xavier Carpena; R Perez; Wendy F Ochoa; Nuria Verdaguer; Martin Klotz; Jack Switala; William Melik-Adamyan; Ignacio Fita; Peter C Loewen
Crystallization and preliminary X-ray analysis of clade I catalases from Pseudomonas syringae and Listeria seeligeri.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 8):1184-6.
2000: Alba Guarné; Bernhard Hampoelz; Walter Glaser; Xavier Carpena; J Tormo; Ignacio Fita; Tim Skern
Structural and biochemical features distinguish the foot-and-mouth disease virus leader proteinase from other papain-like enzymes.
Journal of molecular biology 2000;302(5):1227-40.
2000: Nuria Verdaguer; Dieter Blaas; Ignacio Fita
Structure of human rhinovirus serotype 2 (HRV2).
Journal of molecular biology 2000;300(5):1179-94.
2000: Santiago Ramón-Maiques; Alberto Marina; M Uriarte; Ignacio Fita; Vicente Rubio
The 1.5 A resolution crystal structure of the carbamate kinase-like carbamoyl phosphate synthetase from the hyperthermophilic Archaeon pyrococcus furiosus, bound to ADP, confirms that this thermostable enzyme is a carbamate kinase, and provides insight into substrate binding and stability in carbamate kinases.
Journal of molecular biology 2000;299(2):463-76.
2000: Wendy F Ochoa; Susana G Kalko; Mauricio G Mateu; P Gomes; David Andreu; Esteban Domingo; Ignacio Fita; Nuria Verdaguer
A multiply substituted G-H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: a role for water molecules.
The Journal of general virology 2000;81(Pt 6):1495-505.
2000: Susana G Kalko; Monica Chagoyen; N Jiménez-Lozano; Nuria Verdaguer; Ignacio Fita; J M Carazo
The need for a shared database infrastructure: combining X-ray crystallography and electron microscopy.
European biophysics journal : EBJ 2000;29(6):457-62.
1999: Nuria Verdaguer; Senena Corbalan-Garcia; Wendy F Ochoa; Ignacio Fita; Juan C Gómez-Fernández
Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine.
The EMBO journal 1999;18(22):6329-38.
1999: María J Maté; MS Sevinc; B Hu; J Bujons; J Bravo; Jack Switala; Werner Ens; Peter C Loewen; Ignacio Fita
Mutants that alter the covalent structure of catalase hydroperoxidase II from Escherichia coli.
The Journal of biological chemistry 1999;274(39):27717-25.
1999: Esteban Domingo; Nuria Verdaguer; Wendy F Ochoa; Carmen M Ruiz-Jarabo; Noemí Sevilla; Eric Baranowski; Mauricio G Mateu; Ignacio Fita
Biochemical and structural studies with neutralizing antibodies raised against foot-and-mouth disease virus.
Virus research 1999;62(2):169-75.
1999: Joachim Seipelt; Alba Guarné; E Bergmann; M James; Wolfgang Sommergruber; Ignacio Fita; Tim Skern
The structures of picornaviral proteinases.
Virus research 1999;62(2):159-68.
1999: Nuria Verdaguer; TC Marlovits; J Bravo; D I Stuart; Dieter Blaas; Ignacio Fita
Crystallization and preliminary X-ray analysis of human rhinovirus serotype 2 (HRV2).
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 8):1459-61.
1999: F Gil; Santiago Ramón-Maiques; Alberto Marina; Ignacio Fita; Vicente Rubio
N-Acetyl-L-glutamate kinase from Escherichia coli: cloning of the gene, purification and crystallization of the recombinant enzyme and preliminary X-ray analysis of the free and ligand-bound forms.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 7):1350-2.
1999: M Uriarte; Alberto Marina; Santiago Ramón-Maiques; Ignacio Fita; Vicente Rubio
The carbamoyl-phosphate synthetase of Pyrococcus furiosus is enzymologically and structurally a carbamate kinase.
The Journal of biological chemistry 1999;274(23):16295-303.
1999: María J Maté; Miguel Ortiz-Lombardía; Alberto Marina; Ignacio Fita
Crystallization and preliminary structural results of catalase from human erythrocytes.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 5):1066-8.
1999: Alberto Marina; Pedro Alzari; J Bravo; M Uriarte; B Barcelona; Ignacio Fita; Vicente Rubio
Carbamate kinase: New structural machinery for making carbamoyl phosphate, the common precursor of pyrimidines and arginine.
Protein science : a publication of the Protein Society 1999;8(4):934-40.
1999: Nuria Verdaguer; Guy Schoehn; Wendy F Ochoa; Ignacio Fita; S Brookes; A King; Esteban Domingo; Mauricio G Mateu; D Stuart; Elizabeth A Hewat
Flexibility of the major antigenic loop of foot-and-mouth disease virus bound to a Fab fragment of a neutralising antibody: structure and neutralisation.
Virology 1999;255(2):260-8.
1999: MS Sevinc; María J Maté; Jack Switala; Ignacio Fita; Peter C Loewen
Role of the lateral channel in catalase HPII of Escherichia coli.
Protein science : a publication of the Protein Society 1999;8(3):490-8.
1999: María J Maté; M Zamocky; L M Nykyri; C Herzog; Pedro Alzari; C Betzel; F Koller; Ignacio Fita
Structure of catalase-A from Saccharomyces cerevisiae.
Journal of molecular biology 1999;286(1):135-49.
1999: J Bravo; M J Mate; T Schneider; Jack Switala; K Wilson; Peter C Loewen; Ignacio Fita
Structure of catalase HPII from Escherichia coli at 1.9 A resolution.
Proteins 1999;34(2):155-66.
1999: Jose M Carazo; E H Stelzer; A Engel; Ignacio Fita; C Henn; J Machtynger; P McNeil; DM Shotton; Monica Chagoyen; Pedro A De-Alarcón; R Fritsch; J Bernard Heymann; Susana G Kalko; J J Pittet; P Rodriguez-Tomé; T Boudier
Organising multi-dimensional biological image information: the BioImage Database.
Nucleic acids research 1999;27(1):280-3.
1998: Alba Guarné; J Tormo; R Kirchweger; D Pfistermueller; Ignacio Fita; Tim Skern
Structure of the foot-and-mouth disease virus leader protease: a papain-like fold adapted for self-processing and eIF4G recognition.
The EMBO journal 1998;17(24):7469-79.
1998: MS Sevinc; Jack Switala; J Bravo; Ignacio Fita; Peter C Loewen
Truncation and heme pocket mutations reduce production of functional catalase HPII in Escherichia coli.
Protein engineering 1998;11(7):549-55.
1998: MA Molins; M A Contreras; Ignacio Fita; Miquel Pons
Solution conformation of an immunogenic peptide from HRV2: comparison with the conformation found in a complex with a Fab fragment of an anti-HRV2 neutralizing antibody.
Journal of peptide science : an official publication of the European Peptide Society 1998;4(2):101-10.
1998: Tim Skern; Ignacio Fita; Alba Guarné
A structural model of picornavirus leader proteinases based on papain and bleomycin hydrolase.
The Journal of general virology 1998;79 ( Pt 2)():301-7.
1998: Nuria Verdaguer; Noemí Sevilla; M L Valero; D Stuart; Emiliana Brocchi; David Andreu; E Giralt; Esteban Domingo; Mauricio G Mateu; Ignacio Fita
A similar pattern of interaction for different antibodies with a major antigenic site of foot-and-mouth disease virus: implications for intratypic antigenic variation.
Journal of virology 1998;72(1):739-48.
1997: Nuria Verdaguer; Ignacio Fita; Esteban Domingo; Mauricio G Mateu
Efficient neutralization of foot-and-mouth disease virus by monovalent antibody binding.
Journal of virology 1997;71(12):9813-6.
1997: J Bravo; Ignacio Fita; Juan C Ferrer; Werner Ens; Alexander Hillar; Jack Switala; Peter C Loewen
Identification of a novel bond between a histidine and the essential tyrosine in catalase HPII of Escherichia coli.
Protein science : a publication of the Protein Society 1997;6(5):1016-23.
1997: Elizabeth A Hewat; Nuria Verdaguer; Ignacio Fita; W Blakemore; S Brookes; A King; J Newman; Esteban Domingo; Mauricio G Mateu; D I Stuart
Structure of the complex of an Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop.
The EMBO journal 1997;16(7):1492-500.
1997: S Berthet; L M Nykyri; J Bravo; M J Mate; C Berthet-Colominas; Pedro Alzari; F Koller; Ignacio Fita
Crystallization and preliminary structural analysis of catalase A from Saccharomyces cerevisiae.
Protein science : a publication of the Protein Society 1997;6(2):481-3.
1996: Alba Guarné; R Kirchweger; Nuria Verdaguer; Hans-Dieter Liebig; Dieter Blaas; Tim Skern; Ignacio Fita
Crystallization and preliminary X-ray diffraction studies of the Lb proteinase from foot-and-mouth disease virus.
Protein science : a publication of the Protein Society 1996;5(9):1931-3.
1996: Garib N Murshudov; A I Grebenko; V Barynin; Zbigniew Dauter; Keith S Wilson; B K Vainshtein; W Melik-Adamyan; J Bravo; J M Ferrán; J C Ferrer; Jack Switala; Peter C Loewen; Ignacio Fita
Structure of the heme d of Penicillium vitale and Escherichia coli catalases.
The Journal of biological chemistry 1996;271(15):8863-8.
1996: Nuria Verdaguer; Mauricio G Mateu; J Bravo; E Domingo; Ignacio Fita
Induced pocket to accommodate the cell attachment Arg-Gly-Asp motif in a neutralizing antibody against foot-and-mouth-disease virus.
Journal of molecular biology 1996;256(2):364-76.
1996: Alba Guarné; J Bravo; J Calvo; F Lozano; J Vives; Ignacio Fita
Conformation of the hypervariable region L3 without the key proline residue.
Protein science : a publication of the Protein Society 1996;5(1):167-9.
1995: J Tormo; N B Centeno; E Fontana; T Bubendorfer; Ignacio Fita; Dieter Blaas
Docking of a human rhinovirus neutralizing antibody onto the viral capsid.
Proteins 1995;23(4):491-501.
1995: Alberto Marina; J Bravo; Ignacio Fita; Vicente Rubio
Crystallization, characterization, and preliminary crystallographic studies of mitochondrial carbamoyl phosphate synthetase I of Rana catesbeiana.
Proteins 1995;22(2):193-6.
1995: J Bravo; Nuria Verdaguer; J Tormo; C Betzel; Jack Switala; Peter C Loewen; Ignacio Fita
Crystal structure of catalase HPII from Escherichia coli.
Structure (London, England : 1993) 1995;3(5):491-502.
1995: Nuria Verdaguer; Mauricio G Mateu; David Andreu; Ernest Giralt; E Domingo; Ignacio Fita
Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg-Gly-Asp motif in the interaction.
The EMBO journal 1995;14(8):1690-6.
1995: M L Valero; Julio A Camarero; A Adeva; Nuria Verdaguer; Ignacio Fita; Mauricio G Mateu; Esteban Domingo; Ernest Giralt; David Andreu
Cyclic peptides as conformationally restricted models of viral antigens: application to foot-and-mouth disease virus.
Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity 1995;1(3):133-40.
1995: Esteban Domingo; Mauricio G Mateu; Cristina Escarmís; Encarnación Martínez-Salas; David Andreu; Ernest Giralt; Nuria Verdaguer; Ignacio Fita
Molecular evolution of aphthoviruses.
Virus genes 1995;11(2-3):197-207.
1994: L Boqué; M Gràcia Coll; Maria Vilanova; Claudi M Cuchillo; Ignacio Fita
Structure of ribonuclease A derivative II at 2.1-A resolution.
The Journal of biological chemistry 1994;269(31):19707-12.
1994: J Tormo; Dieter Blaas; N R Parry; D Rowlands; David Stuart; Ignacio Fita
Crystal structure of a human rhinovirus neutralizing antibody complexed with a peptide derived from viral capsid protein VP2.
The EMBO journal 1994;13(10):2247-56.
1994: X de la Cruz; Alan E Mark; J Tormo; Ignacio Fita; Wilfred F van Gunsteren
Investigation of shape variations in the antibody binding site by molecular dynamics computer simulation.
Journal of molecular biology 1994;236(4):1186-95.
1994: Nuria Verdaguer; Mauricio G Mateu; J Bravo; J Tormo; Ernest Giralt; David Andreu; E Domingo; Ignacio Fita
Crystallization and preliminary X-ray diffraction studies of a monoclonal antibody Fab fragment against foot-and-mouth disease virus and of its complex with the main antigenic site peptide.
Proteins 1994;18(2):201-3.
1994: Alberto Marina; J Bravo; Ignacio Fita; Vicente Rubio
Crystallization, characterization and preliminary crystallographic studies of carbamate kinase of Streptococcus faecium.
Journal of molecular biology 1994;235(4):1345-7.
1993: L Tabernero; Nuria Verdaguer; Miquel Coll; Ignacio Fita; G A van der Marel; J H van Boom; A Rich; J Aymamí
Molecular structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor groove binding drug netropsin.
Biochemistry 1993;32(33):8403-10.
1992: J Tormo; E Stadler; Tim Skern; H Auer; O Kanzler; C Betzel; Dieter Blaas; Ignacio Fita
Three-dimensional structure of the Fab fragment of a neutralizing antibody to human rhinovirus serotype 2.
Protein science : a publication of the Protein Society 1992;1(9):1154-61.
1992: J Tormo; J Puiggali; J Vives; Ignacio Fita; J Lloveras; J Bella; J Aymamí; Juan A Subirana
Crystal structure of a helical oligopeptide model of polyglycine II and of other polyamides: acetyl-(glycyl-beta-alanyl)2-NH propyl.
Biopolymers 1992;32(6):643-8.
1992: X de la Cruz; J Reverter; Ignacio Fita
Representation of noncovalent interactions in protein structures.
Journal of molecular graphics 1992;10(2):96-100, 110.
1991: Nuria Verdaguer; J Aymami; D Fernández-Forner; Ignacio Fita; Miquel Coll; Tam Huynh-Dinh; J Igolen; Juan A Subirana
Molecular structure of a complete turn of A-DNA.
Journal of molecular biology 1991;221(2):623-35.
1990: J Tormo; Ignacio Fita; O Kanzler; Dieter Blaas
Crystallization and preliminary x-ray diffraction studies of the Fab fragment of a neutralizing monoclonal antibody directed against human rhinovirus serotype 2.
The Journal of biological chemistry 1990;265(28):16799-800.
1990: Nuria Verdaguer; Ignacio Fita; Juan A Subirana
Molecular structure of L-lysyl-L-tyrosyl-L-serine acetate.
International journal of biological macromolecules 1990;12(5):315-20.
1990: J Tormo; Ignacio Fita; Jack Switala; Peter C Loewen
Crystallization and preliminary X-ray diffraction analysis of catalase HPII from Escherichia coli.
Journal of molecular biology 1990;213(2):219-20.
1989: L Urpi; J P Ridoux; Jean Liquier; Nuria Verdaguer; Ignacio Fita; Juan A Subirana; F Iglesias; Tam Huynh-Dinh; J Igolen; Eliane Taillandier
Conformations in crystals and solutions of d(CACGTG), d(CCGCGG) and d(GGCGCC) studied by vibrational spectroscopy.
Nucleic acids research 1989;17(16):6669-80.
1988: Nuria Verdaguer; L Urpí; Ignacio Fita; Juan A Subirana
Molecular structure of L-lysyl-L-alanyl-L-alanine: a tripeptide found in histone H1.
Biopolymers 1988;27(12):1887-96.
1988: Miquel Coll; Ignacio Fita; J Lloveras; Juan A Subirana; F Bardella; Tam Huynh-Dinh; J Igolen
Structure of d(CACGTG), a Z-DNA hexamer containing AT base pairs.
Nucleic acids research 1988;16(17):8695-705.
1986: W R Melik-Adamyan; V V Barynin; Alexei A Vagin; V V Borisov; B K Vainshtein; Ignacio Fita; M R Murthy; M G Rossmann
Comparison of beef liver and Penicillium vitale catalases.
Journal of molecular biology 1986;188(1):63-72.
1986: B K Vainshtein; W R Melik-Adamyan; V V Barynin; Alexei A Vagin; A I Grebenko; V V Borisov; K S Bartels; Ignacio Fita; M G Rossmann
Three-dimensional structure of catalase from Penicillium vitale at 2.0 A resolution.
Journal of molecular biology 1986;188(1):49-61.