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Gregory Fitz

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Ishtiaq Qadri; Shaikh Mizanoor Rahman; Jerome Schaack; Francis R Simon; Mieko Iwahashi; Rachel C Janssen; Gordan Kilic; Trina A Knotts; Livia Puljak; Mahua Choudhury; J Gregory Fitz; Jacob E Friedman
Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein β.
Svjetlana Dolovcak; Shar L Waldrop; J Gregory Fitz; Gordan Kilic
Copper inhibits P2Y(2)-dependent Ca(2+) signaling through the effects on thapsigargin-sensitive Ca(2+) stores in HTC hepatoma cells.
Svjetlana Dolovcak; Sharon Waldrop; J Gregory Fitz; Gordan Kilic
5-Nitro-2-(3-phenylpropylamino)benzoic acid (NPPB) stimulates cellular ATP release through exocytosis of ATP-enriched vesicles.

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All Publications

2012: Ishtiaq Qadri; Shaikh Mizanoor Rahman; Jerome Schaack; Francis R Simon; Mieko Iwahashi; Rachel C Janssen; Gordan Kilic; Trina A Knotts; Livia Puljak; Mahua Choudhury; J Gregory Fitz; Jacob E Friedman
Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein β.
The Journal of biological chemistry 2012;287(44):37340-51.
2010: Svjetlana Dolovcak; Shar L Waldrop; J Gregory Fitz; Gordan Kilic
Copper inhibits P2Y(2)-dependent Ca(2+) signaling through the effects on thapsigargin-sensitive Ca(2+) stores in HTC hepatoma cells.
Biochemical and biophysical research communications 2010;397(3):493-8.
2009: Svjetlana Dolovcak; Sharon Waldrop; J Gregory Fitz; Gordan Kilic
5-Nitro-2-(3-phenylpropylamino)benzoic acid (NPPB) stimulates cellular ATP release through exocytosis of ATP-enriched vesicles.
The Journal of biological chemistry 2009;284(49):33894-903.
2008: Livia Puljak; Vinay Parameswara; Svjetlana Dolovcak; Shar L Waldrop; Daniel Emmett; Victoria Esser; J Gregory Fitz; Gordan Kilic
Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line.
Experimental cell research 2008;314(10):2100-9.
2008: Erik M Schwiebert; J Gregory Fitz
Purinergic signaling microenvironments: An introduction.
Purinergic signalling 2008;4(2):89-92.
2008: Daniel S Emmett; Andrew P Feranchak; Gordan Kilic; Livia Puljak; Bonnie Miller; Svjetlana Dolovcak; Ryan R McWilliams; R Brian Doctor; J Gregory Fitz
Characterization of ionotrophic purinergic receptors in hepatocytes.
Hepatology (Baltimore, Md.) 2008;47(2):698-705.
2007: Andrew P Feranchak; J Gregory Fitz
Thinking outside the cell: the role of extracellular adenosine triphosphate in bile formation.
Gastroenterology 2007;133(5):1726-8.
2007: R Brian Doctor; Sylene Johnson; Kelley S Brodsky; Claudia R Amura; Vincent H Gattone; J Gregory Fitz
Regulated ion transport in mouse liver cyst epithelial cells.
Biochimica et biophysica acta 2007;1772(3):345-54.
2005: R Brian Doctor; Thomas Matzakos; Ryan R McWilliams; Sylene Johnson; Andrew P Feranchak; J Gregory Fitz
Purinergic regulation of cholangiocyte secretion: identification of a novel role for P2X receptors.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(4):G779-86.
2005: Livia Puljak; Michael J Pagliassotti; Yuren Wei; Ishtiaq Qadri; Vinay Parameswara; Victoria Esser; J Gregory Fitz; Gordan Kilic
Inhibition of cellular responses to insulin in a rat liver cell line. A role for PKC in insulin resistance.
The Journal of physiology 2005;563(Pt 2):471-82.
2004: Matthew T Nichols; Elizabeth Gidey; Tom Matzakos; Rolf Dahl; Gregory V Stiegmann; Raj J Shah; Jared J Grantham; J Gregory Fitz; R Brian Doctor
Secretion of cytokines and growth factors into autosomal dominant polycystic kidney disease liver cyst fluid.
Hepatology (Baltimore, Md.) 2004;40(4):836-46.
2004: Andrew P Feranchak; R Brian Doctor; Marlyn Troetsch; Kathryn Brookman; Sylene M Johnson; J Gregory Fitz
Calcium-dependent regulation of secretion in biliary epithelial cells: the role of apamin-sensitive SK channels.
Gastroenterology 2004;127(3):903-13.
2004: David Gatof; Gordan Kilic; J Gregory Fitz
Vesicular exocytosis contributes to volume-sensitive ATP release in biliary cells.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(4):G538-46.
2003: Andrew P Feranchak; Gordan Kilic; Paul A Wojtaszek; Ishtiaq Qadri; J Gregory Fitz
Volume-sensitive tyrosine kinases regulate liver cell volume through effects on vesicular trafficking and membrane Na+ permeability.
The Journal of biological chemistry 2003;278(45):44632-8.
2002: Andrew P Feranchak; J Gregory Fitz
Adenosine triphosphate release and purinergic regulation of cholangiocyte transport.
Seminars in liver disease 2002;22(3):251-62.
2002: J Gregory Fitz
Regulation of cholangiocyte secretion.
Seminars in liver disease 2002;22(3):241-9.
2002: J Gregory Fitz
Current concepts in developmental, physiologic, and pathophysiologic aspects of cholangiocyte biology.
Seminars in liver disease 2002;22(3):211-2.
2002: R Brian Doctor; Rolf Dahl; Laura Fouassier; Gordan Kilic; J Gregory Fitz
Cholangiocytes exhibit dynamic, actin-dependent apical membrane turnover.
American journal of physiology. Cell physiology 2002;282(5):C1042-52.
2002: Gordan Kilic; J Gregory Fitz
Heterotrimeric G-proteins activate Cl- channels through stimulation of a cyclooxygenase-dependent pathway in a model liver cell line.
The Journal of biological chemistry 2002;277(14):11721-7.
2002: Richard Roman; Andrew P Feranchak; Marlyn Troetsch; Jeffrey C Dunkelberg; Gordan Kilic; Thorsten Schlenker; Jerome Schaack; J Gregory Fitz
Molecular characterization of volume-sensitive SK(Ca) channels in human liver cell lines.
American journal of physiology. Gastrointestinal and liver physiology 2002;282(1):G116-22.
2001: Andrew P Feranchak; Tomas Berl; Juan M Capasso; Paul A Wojtaszek; J Han; J Gregory Fitz
p38 MAP kinase modulates liver cell volume through inhibition of membrane Na+ permeability.
The Journal of clinical investigation 2001;108(10):1495-504.
2001: RM Roman; Noureddine Lomri; G Braunstein; Andrew P Feranchak; Luiz Simeoni; A K Davison; Eugene Mechetner; Erik M Schwiebert; J Gregory Fitz
Evidence for multidrug resistance-1 P-glycoprotein-dependent regulation of cellular ATP permeability.
The Journal of membrane biology 2001;183(3):165-73.
2001: Gordan Kilic; R Brian Doctor; J Gregory Fitz
Insulin stimulates membrane conductance in a liver cell line: evidence for insertion of ion channels through a phosphoinositide 3-kinase-dependent mechanism.
The Journal of biological chemistry 2001;276(29):26762-8.
2001: Jeffrey C Dunkelberg; Andrew P Feranchak; J Gregory Fitz
Liver cell volume regulation: size matters.
Hepatology (Baltimore, Md.) 2001;33(6):1349-52.
2001: Gavin M Braunstein; RM Roman; John P Clancy; Brian A Kudlow; Amanda L Taylor; V G Shylonsky; Biljana Jovov; Krisztina Peter; T Jilling; Iskander I Ismailov; Dale J Benos; Lisa M Schwiebert; J Gregory Fitz; Erik M Schwiebert
Cystic fibrosis transmembrane conductance regulator facilitates ATP release by stimulating a separate ATP release channel for autocrine control of cell volume regulation.
The Journal of biological chemistry 2001;276(9):6621-30.
2001: RM Roman; RL Smith; Andrew P Feranchak; Gerald H Clayton; R Brian Doctor; J Gregory Fitz
ClC-2 chloride channels contribute to HTC cell volume homeostasis.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(3):G344-53.
2001: Laura Fouassier; C Y Duan; Andrew P Feranchak; C H Yun; Eileen Sutherland; Francis R Simon; J Gregory Fitz; R Brian Doctor
Ezrin-radixin-moesin-binding phosphoprotein 50 is expressed at the apical membrane of rat liver epithelia.
Hepatology (Baltimore, Md.) 2001;33(1):166-76.
2000: Kelli D Salter; RM Roman; N R LaRusso; J Gregory Fitz; R Brian Doctor
Modified culture conditions enhance expression of differentiated phenotypic properties of normal rat cholangiocytes.
Laboratory investigation; a journal of technical methods and pathology 2000;80(11):1775-8.
2000: Laura Fouassier; C C Yun; J Gregory Fitz; R Brian Doctor
Evidence for ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) self-association through PDZ-PDZ interactions.
The Journal of biological chemistry 2000;275(32):25039-45.
2000: Andrew P Feranchak; J Gregory Fitz; RM Roman
Volume-sensitive purinergic signaling in human hepatocytes.
Journal of hepatology 2000;33(2):174-82.
2000: R Brian Doctor; RH Dahl; Kelli D Salter; Laura Fouassier; J Chen; J Gregory Fitz
ATP depletion in rat cholangiocytes leads to marked internalization of membrane proteins.
Hepatology (Baltimore, Md.) 2000;31(5):1045-54.
2000: Kelli D Salter; J Gregory Fitz; RM Roman
Domain-specific purinergic signaling in polarized rat cholangiocytes.
American journal of physiology. Gastrointestinal and liver physiology 2000;278(3):G492-500.
2000: Thorsten Schlenker; Andrew P Feranchak; Lukas Schwake; Wolfgang Stremmel; RM Roman; J Gregory Fitz
Functional interactions between oxidative stress, membrane Na(+) permeability, and cell volume in rat hepatoma cells.
Gastroenterology 2000;118(2):395-403.
1999: RM Roman; Andrew P Feranchak; A K Davison; Erik M Schwiebert; J Gregory Fitz
Evidence for Gd(3+) inhibition of membrane ATP permeability and purinergic signaling.
The American journal of physiology 1999;277(6 Pt 1):G1222-30.
1999: Andrew P Feranchak; RM Roman; R Brian Doctor; Kelli D Salter; A Toker; J Gregory Fitz
The lipid products of phosphoinositide 3-kinase contribute to regulation of cholangiocyte ATP and chloride transport.
The Journal of biological chemistry 1999;274(43):30979-86.
1999: RM Roman; Andrew P Feranchak; Kelli D Salter; Y Wang; J Gregory Fitz
Endogenous ATP release regulates Cl- secretion in cultured human and rat biliary epithelial cells.
The American journal of physiology 1999;276(6 Pt 1):G1391-400.
1999: R Brian Doctor; RH Dahl; Kelli D Salter; J Gregory Fitz
Reorganization of cholangiocyte membrane domains represents an early event in rat liver ischemia.
Hepatology (Baltimore, Md.) 1999;29(5):1364-74.
1999: RM Roman; J Gregory Fitz
Emerging roles of purinergic signaling in gastrointestinal epithelial secretion and hepatobiliary function.
Gastroenterology 1999;116(4):964-79.
1998: Allan W Wolkoff; Frederick J Suchy; Richard H Moseley; Peter Meier; John L Md Gollan; Nelson B Freimer; J Gregory Fitz; J L Boyer; P D Berk; Bruce F Scharschmidt
Advances in hepatic transport: molecular mechanisms, genetic disorders, and treatment. A summary of the 1998 AASLD single topic conference.
Hepatology (Baltimore, Md.) 1998;28(6):1713-9.
1998: Veronica Prpic; J Gregory Fitz; Yu Wang; John R Raymond; Maria N Garnovskaya; Rodger A Liddle
Inhibition of Na+/H+ exchange stimulates CCK secretion in STC-1 cells.
The American journal of physiology 1998;275(4 Pt 1):G689-95.
1998: RM Roman; K O Bodily; Y Wang; John R Raymond; J Gregory Fitz
Activation of protein kinase Calpha couples cell volume to membrane Cl- permeability in HTC hepatoma and Mz-ChA-1 cholangiocarcinoma cells.
Hepatology (Baltimore, Md.) 1998;28(4):1073-80.
1998: Andrew P Feranchak; RM Roman; Erik M Schwiebert; J Gregory Fitz
Phosphatidylinositol 3-kinase contributes to cell volume regulation through effects on ATP release.
The Journal of biological chemistry 1998;273(24):14906-11.
1998: Marie V St Pierre; Thorsten Schlenker; Jean-François Dufour; D M Jefferson; J Gregory Fitz; Irwin M Arias
Stimulation of cyclic guanosine monophosphate production by natriuretic peptide in human biliary cells.
Gastroenterology 1998;114(4):782-90.
1997: Thorsten Schlenker; Joelle Romac; A I Sharara; RM Roman; S J Kim; N LaRusso; Rodger A Liddle; J Gregory Fitz
Regulation of biliary secretion through apical purinergic receptors in cultured rat cholangiocytes.
The American journal of physiology 1997;273(5 Pt 1):G1108-17.
1997: RM Roman; Y Wang; SD Lidofsky; Andrew P Feranchak; Noureddine Lomri; Bruce F Scharschmidt; J Gregory Fitz
Hepatocellular ATP-binding cassette protein expression enhances ATP release and autocrine regulation of cell volume.
The Journal of biological chemistry 1997;272(35):21970-6.
1997: Yu Wang; Richard Roman; Thorsten Schlenker; Yusuf A Hannun; John R Raymond; J Gregory Fitz
Cytosolic Ca2+ and protein kinase Calpha couple cellular metabolism to membrane K+ permeability in a human biliary cell line.
The Journal of clinical investigation 1997;99(12):2890-7.
1997: SD Lidofsky; A Sostman; J Gregory Fitz
Regulation of cation-selective channels in liver cells.
The Journal of membrane biology 1997;157(3):231-6.
1997: K Bodily; Yu Wang; Richard Roman; A Sostman; J Gregory Fitz
Characterization of a swelling-activated anion conductance in homozygous typing cell hepatoma cells.
Hepatology (Baltimore, Md.) 1997;25(2):403-10.
1996: Pierre-Alain Clavien; Ala I Sharara; C A Camargo; robert harland; J Gregory Fitz
Evidence that ursodeoxycholic acid prevents steroid-resistant rejection in adult liver transplantation.
Clinical transplantation 1996;10(6 Pt 2):658-62.
1996: Yu Wang; RM Roman; SD Lidofsky; J Gregory Fitz
Autocrine signaling through ATP release represents a novel mechanism for cell volume regulation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):12020-5.
1996: Thorsten Schlenker; J Gregory Fitz
Ca(2+)-activated C1- channels in a human biliary cell line: regulation by Ca2+/calmodulin-dependent protein kinase.
The American journal of physiology 1996;271(2 Pt 1):G304-10.
1996: RM Roman; Yu Wang; J Gregory Fitz
Regulation of cell volume in a human biliary cell line: activation of K+ and Cl- currents.
The American journal of physiology 1996;271(2 Pt 1):G239-48.
1996: Yu Wang; A Sostman; RM Roman; S Stribling; Steven R Vigna; Yusuf A Hannun; John R Raymond; J Gregory Fitz
Metabolic stress opens K+ channels in hepatoma cells through a Ca2+- and protein kinase calpha-dependent mechanism.
The Journal of biological chemistry 1996;271(30):18107-13.
1996: Noureddine Lomri; J Gregory Fitz; Bruce F Scharschmidt
Hepatocellular transport: role of ATP-binding cassette proteins.
Seminars in liver disease 1996;16(2):201-10.
1996: S M Schutz; J Gregory Fitz; Malcolm S Branch; John Baillie
A new way to obtain contrast-free bile during ERCP.
Gastrointestinal endoscopy 1996;43(3):231-2.
1996: Ravi Chari; S M Schutz; J E Haebig; G H Shimokura; Peter B Cotton; J Gregory Fitz; William C Meyers
Adenosine nucleotides in bile.
The American journal of physiology 1996;270(2 Pt 1):G246-52.
1995: G H Shimokura; J M McGill; Thorsten Schlenker; J Gregory Fitz
Ursodeoxycholate increases cytosolic calcium concentration and activates Cl- currents in a biliary cell line.
Gastroenterology 1995;109(3):965-72.
1995: S Kim; V Lakhani; D J Costa; Ala I Sharara; J Gregory Fitz; L W Huang; Kevin G Peters; L A Kindman
Sphingolipid-gated Ca2+ release from intracellular stores of endothelial cells is mediated by a novel Ca(2+)-permeable channel.
The Journal of biological chemistry 1995;270(10):5266-9.
1994: J M McGill; S Basavappa; A W Mangel; G H Shimokura; J P Middleton; J Gregory Fitz
Adenosine triphosphate activates ion permeabilities in biliary epithelial cells.
Gastroenterology 1994;107(1):236-43.
1994: J M McGill; S Basavappa; Thomas W Gettys; J Gregory Fitz
Secretin activates Cl- channels in bile duct epithelial cells through a cAMP-dependent mechanism.
The American journal of physiology 1994;266(4 Pt 1):G731-6.
1994: J Gregory Fitz; A H Sostman
Nucleotide receptors activate cation, potassium, and chloride currents in a liver cell line.
The American journal of physiology 1994;266(4 Pt 1):G544-53.
1994: J Gregory Fitz; A H Sostman; J P Middleton
Regulation of cation channels in liver cells by intracellular calcium and protein kinase C.
The American journal of physiology 1994;266(4 Pt 1):G677-84.
1993: Jonathan A Cohn; T V Strong; Marina R Picciotto; Angus Nairn; Francis S Collins; J Gregory Fitz
Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cells.
Gastroenterology 1993;105(6):1857-64.
1993: SD Lidofsky; M H Xie; A Sostman; Bruce F Scharschmidt; J Gregory Fitz
Vasopressin increases cytosolic sodium concentration in hepatocytes and activates calcium influx through cation-selective channels.
The Journal of biological chemistry 1993;268(20):14632-6.
1993: J Gregory Fitz; SD Lidofsky; Bruce F Scharschmidt
Regulation of hepatic Na(+)-HCO3- cotransport and pH by membrane potential difference.
The American journal of physiology 1993;265(1 Pt 1):G1-8.
1993: A W Mangel; N D Snow; Mary A Misukonis; S Basavappa; J P Middleton; J Gregory Fitz; Rodger A Liddle
Calcium-dependent regulation of cholecystokinin secretion and potassium currents in STC-1 cells.
The American journal of physiology 1993;264(6 Pt 1):G1031-6.
1993: S Basavappa; J Middleton; A W Mangel; J M McGill; Jonathan A Cohn; J Gregory Fitz
Cl- and K+ transport in human biliary cell lines.
Gastroenterology 1993;104(6):1796-805.
1993: J P Middleton; A W Mangel; S Basavappa; J Gregory Fitz
Nucleotide receptors regulate membrane ion transport in renal epithelial cells.
The American journal of physiology 1993;264(5 Pt 2):F867-73.
1993: J M McGill; Thomas W Gettys; S Basavappa; J Gregory Fitz
GTP-binding proteins regulate high conductance anion channels in rat bile duct epithelial cells.
The Journal of membrane biology 1993;133(3):253-61.
1993: SD Lidofsky; J Gregory Fitz; Richard A Weisiger; Bruce F Scharschmidt
Hepatic taurocholate uptake is electrogenic and influenced by transmembrane potential difference.
The American journal of physiology 1993;264(3 Pt 1):G478-85.
1993: A W Mangel; John R Raymond; J Gregory Fitz
Regulation of high-conductance anion channels by G proteins and 5-HT1A receptors in CHO cells.
The American journal of physiology 1993;264(3 Pt 2):F490-5.
1993: SD Lidofsky; J Gregory Fitz; Bruce F Scharschmidt
Mechanisms and functional role of intracellular pH regulation in hepatocytes.
Progress in liver diseases 1993;11():69-83.
1993: J Gregory Fitz; S Basavappa; J McGill; O Melhus; Jonathan A Cohn
Regulation of membrane chloride currents in rat bile duct epithelial cells.
The Journal of clinical investigation 1993;91(1):319-28.
1992: A W Mangel; Scott Brazer; J W Smith; J Gregory Fitz; I L Taylor
Inhibition of colonic motility by cholecystokinin.
Annals of medicine 1992;24(5):341-2.
1992: A W Mangel; S Basavappa; John R Raymond; J Gregory Fitz
cAMP-regulated chloride currents in CHO cells.
Biochemical and biophysical research communications 1992;186(1):251-5.
1992: Ala I Sharara; T J Panella; J Gregory Fitz
Paraneoplastic hepatopathy associated with soft tissue sarcoma.
Gastroenterology 1992;103(1):330-2.
1992: J Gregory Fitz; SD Lidofsky; M H Xie; Bruce F Scharschmidt
Transmembrane electrical potential difference regulates Na+/HCO3- cotransport and intracellular pH in hepatocytes.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):4197-201.
1992: J M McGill; S Basavappa; J Gregory Fitz
Characterization of high-conductance anion channels in rat bile duct epithelial cells.
The American journal of physiology 1992;262(4 Pt 1):G703-10.
1991: J Gregory Fitz; SD Lidofsky; M H Xie; M Cochran; Bruce F Scharschmidt
Plasma membrane H(+)-HCO3- transport in rat hepatocytes: a principal role for Na(+)-coupled HCO3- transport.
The American journal of physiology 1991;261(5 Pt 1):G803-9.
1991: A W Mangel; J Gregory Fitz; I L Taylor
Modulation of colonic motility by substance P, cholecystokinin and neuropeptide Y.
Peptides 1991;12(5):1063-7.
1991: J Gregory Fitz; Nathan M Bass; Richard A Weisiger
Hepatic transport of a fluorescent stearate derivative: electrochemical driving forces in intact rat liver.
The American journal of physiology 1991;261(1 Pt 1):G83-91.
1991: J Gregory Fitz; SD Lidofsky; Richard A Weisiger; M H Xie; M Cochran; T Grotmol; Bruce F Scharschmidt
HCO3(-)-coupled Na+ influx is a major determinant of Na+ turnover and Na+/K+ pump activity in rat hepatocytes.
The Journal of membrane biology 1991;122(1):1-10.
1991: A W Mangel; J Gregory Fitz; I L Taylor
Peptides do not induce contractions in gastrointestinal smooth muscle in calcium-free solution.
General pharmacology 1991;22(6):1135-7.
1989: J Gregory Fitz; T E Trouillot; Bruce F Scharschmidt
Effect of pH on membrane potential and K+ conductance in cultured rat hepatocytes.
The American journal of physiology 1989;257(6 Pt 1):G961-8.
1989: J Gregory Fitz; M Persico; Bruce F Scharschmidt
Electrophysiological evidence for Na+-coupled bicarbonate transport in cultured rat hepatocytes.
The American journal of physiology 1989;256(3 Pt 1):G491-500.
1989: Richard A Weisiger; J Gregory Fitz; Bruce F Scharschmidt
Hepatic oleate uptake. Electrochemical driving forces in intact rat liver.
The Journal of clinical investigation 1989;83(2):411-20.
1988: Richard A Weisiger; J Gregory Fitz
Sex differences in membrane potential in the intact perfused rat liver.
The American journal of physiology 1988;255(6 Pt 1):G822-5.
1988: T L Wright; J Gregory Fitz; Richard A Weisiger
Non-transferrin-bound iron uptake by rat liver. Role of membrane potential difference.
The Journal of biological chemistry 1988;263(4):1842-7.