FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Desmond Fitzgerald

Research Profile

Chemicals & Drugs

Anatomy

Physiology

Co-author Network

Publications

TOP 3
Iain Macaulay; Bryan T MacDonald; Cavan Bennett; Philippa Burns; Desmond J Fitzgerald; Xi He; Joseph E Italiano; Gerardene Meade; Ronan P Murphy; Augusto Rendon; Vishal Salunkhe; Brian M Steele; Jonathan N Thon; Marloes R Tijssen; Nicholas A Watkins; Patricia B Maguire
Canonical Wnt signaling in megakaryocytes regulates proplatelet formation.
Brian M Steele; Alastair W Poole; Albert P Smolenski; Naheda Alkazemi; Desmond J Fitzgerald; Matthew Harper; Patricia B Maguire
WNT-3a modulates platelet function by regulating small GTPase activity.
Cathal McCarthy; Peadar Ó Gaora; William G James; Sarah McClelland; Desmond J Fitzgerald; Monica de Gaetano; Orina Belton
SorLA modulates atheroprotective properties of CLA by regulating monocyte migration.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Desmond Fitzgerald (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Iain Macaulay; Bryan T MacDonald; Cavan Bennett; Philippa Burns; Desmond J Fitzgerald; Xi He; Joseph E Italiano; Gerardene Meade; Ronan P Murphy; Augusto Rendon; Vishal Salunkhe; Brian M Steele; Jonathan N Thon; Marloes R Tijssen; Nicholas A Watkins; Patricia B Maguire
Canonical Wnt signaling in megakaryocytes regulates proplatelet formation.
Blood 2013;121(1):188-96.
2012: Brian M Steele; Alastair W Poole; Albert P Smolenski; Naheda Alkazemi; Desmond J Fitzgerald; Matthew Harper; Patricia B Maguire
WNT-3a modulates platelet function by regulating small GTPase activity.
FEBS letters 2012;586(16):2267-72.
2010: Cathal McCarthy; Peadar Ó Gaora; William G James; Sarah McClelland; Desmond J Fitzgerald; Monica de Gaetano; Orina Belton
SorLA modulates atheroprotective properties of CLA by regulating monocyte migration.
Atherosclerosis 2010;213(2):400-7.
2010: Andrew O Maree; C Vangjeli; H Jneid; J Ryan; Dermot Cox; C P Cannon; Denis C Shields; Desmond J Fitzgerald
G-protein beta3 subunit polymorphism and bleeding in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 trial.
Journal of thrombosis and haemostasis : JTH 2010;8(5):934-41.
2009: Brian M Steele; Matthew Harper; Iain C Macaulay; Craig N Morrell; Alita Perez-Tamayo; Martina Foy; Raymond Habas; Alastair W Poole; Desmond J Fitzgerald; Patricia B Maguire
Canonical Wnt signaling negatively regulates platelet function.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(47):19836-41.
2009: Louise K Brennan; Brian H Harte; Desmond J Fitzgerald; Connail McCrory
Surgery induces cyclooxygenase-2 expression in the rat cervical spinal cord.
Regional anesthesia and pain medicine 2009;34(6):549-52.
2009: Lorna Cryan; Desmond J Fitzgerald; Colm O'Brien
Ocular prostaglandin production and morphology in mice lacking a single isoform of cyclooxygenase.
Prostaglandins, leukotrienes, and essential fatty acids 2009;81(5-6):401-9.
2009: Glen A Doherty; Sinead M Byrne; Eamonn S Molloy; Vikrum Malhotra; Sandra C Austin; Elaine W Kay; Frank E Murray; Desmond J Fitzgerald
Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer.
BMC cancer 2009;9():207.
2008: Eamonn S Molloy; Maria P Morgan; G A Doherty; B McDonnell; M Hilliard; J O'Byrne; Desmond J Fitzgerald; Geraldine M McCarthy
Mechanism of basic calcium phosphate crystal-stimulated cyclo-oxygenase-1 up-regulation in osteoarthritic synovial fibroblasts.
Rheumatology (Oxford, England) 2008;47(7):965-71.
2008: Mary-Clare Cathcart; Rasa Tamosiuniene; Gang Chen; Tomas G Neilan; Aidan Bradford; Kenneth J O'Byrne; Desmond J Fitzgerald; Graham P Pidgeon
Cyclooxygenase-2-linked attenuation of hypoxia-induced pulmonary hypertension and intravascular thrombosis.
The Journal of pharmacology and experimental therapeutics 2008;326(1):51-8.
2008: Lorna Cryan; Luminita Paraoan; Paul Hiscott; Bertil E Damato; Ian Grierson; Donna Gray; Michael Farrell; Glen A Doherty; Desmond J Fitzgerald; Colm O'Brien
Expression of COX-2 and prognostic outcome in uveal melanoma.
Current eye research 2008;33(2):177-84.
2008: Donal F Harney; Michelle Dooley; Brendan harhen; Niall McGuiness; Gerard Cagney; Connail McCrory; Desmond J Fitzgerald; Noreen P Dowd
Nimesulide 90 mg orally twice daily does not influence postoperative morphine requirements after major chest surgery.
Anesthesia and analgesia 2008;106(1):294-300, table of contents.
2007: Paul corcoran; John C Atherton; Steven W Kerrigan; Torkel Wadstrom; Frank E Murray; Richard M Peek; Desmond J Fitzgerald; Dermot M Cox; Michael F Byrne
The effect of different strains of Helicobacter pylori on platelet aggregation.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2007;21(6):367-70.
2007: Judith A Coppinger; Roisin O'Connor; Kieran Wynne; Michelle Flanagan; Matthew Sullivan; Patricia B Maguire; Desmond J Fitzgerald; Gerard Cagney
Moderation of the platelet releasate response by aspirin.
Blood 2007;109(11):4786-92.
2007: Judith A Coppinger; Desmond J Fitzgerald; Patricia B Maguire
Isolation of the platelet releasate.
Methods in molecular biology (Clifton, N.J.) 2007;357():307-11.
2006: Dermot Cox; Andrew O Maree; Michelle Dooley; Ronan Conroy; Michael F Byrne; Desmond J Fitzgerald
Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers.
Stroke; a journal of cerebral circulation 2006;37(8):2153-8.
2006: Ingo Ahrens; Niamh Moran; K Aylward; Gerardene Meade; M Moser; D Assefa; Desmond J Fitzgerald; Christoph Bode; Karlheinz Peter
Evidence for a differential functional regulation of the two beta(3)-integrins alpha(V)beta(3) and alpha(IIb)beta(3).
Experimental cell research 2006;312(6):925-37.
2006: Aisling M O'Halloran; Ronan Curtin; Fiona O'Connor; Michelle Dooley; Anthony Fitzgerald; John K O'Brien; Desmond J Fitzgerald; Denis C Shields
The impact of genetic variation in the region of the GPIIIa gene, on Pl expression bias and GPIIb/IIIa receptor density in platelets.
British journal of haematology 2006;132(4):494-502.
2006: Anthony Chubb; Desmond J Fitzgerald; Kevin B Nolan; Edelmiro Moman
The productive conformation of prostaglandin G2 at the peroxidase site of prostaglandin endoperoxide H synthase: docking, molecular dynamics, and site-directed mutagenesis studies.
Biochemistry 2006;45(3):811-20.
2006: Lorna Cryan; Graham P Pidgeon; Desmond J Fitzgerald; Colm J O'Brien
COX-2 protects against thrombosis of the retinal vasculature in a mouse model of proliferative retinopathy.
Molecular vision 2006;12():405-14.
2005: Jean Lee; Anthony Chubb; Edelmiro Moman; Brian M McLoughlin; Caroline T Sharkey; John G Kelly; Kevin B Nolan; Marc Devocelle; Desmond J Fitzgerald
Parallel synthesis and in vitro activity of novel anthranilic hydroxamate-based inhibitors of the prostaglandin H2 synthase peroxidase activity.
Organic & biomolecular chemistry 2005;3(20):3678-85.
2005: Andrew O Maree; Ronan Curtin; Michelle Dooley; Ronan Conroy; Peter Crean; Dermot Cox; Desmond J Fitzgerald
Platelet response to low-dose enteric-coated aspirin in patients with stable cardiovascular disease.
Journal of the American College of Cardiology 2005;46(7):1258-63.
2005: Andrew O Maree; Ronan Curtin; Anthony Chubb; C Dolan; Dermot Cox; J O'Brien; P Crean; Denis C Shields; Desmond J Fitzgerald
Cyclooxygenase-1 haplotype modulates platelet response to aspirin.
Journal of thrombosis and haemostasis : JTH 2005;3(10):2340-5.
2005: Patricia B Maguire; Martina Foy; Desmond J Fitzgerald
Using proteomics to identify potential therapeutic targets in platelets.
Biochemical Society transactions 2005;33(Pt 2):409-12.
2004: Graham P Pidgeon; Rasa Tamosiuniene; Gang Chen; Irene Leonard; Orina Belton; Aidan Bradford; Desmond J Fitzgerald
Intravascular thrombosis after hypoxia-induced pulmonary hypertension: regulation by cyclooxygenase-2.
Circulation 2004;110(17):2701-7.
2004: James P McRedmond; N T Mulvihill; M Kane; B Burke; B Aloul; TONY FORDE; M Walsh; Desmond J Fitzgerald
A rapid agglutination assay to detect anti-streptokinase antibodies.
Irish journal of medical science 2004;173(4):204-10.
2004: Patricia B Maguire; Niamh Moran; Gerard Cagney; Desmond J Fitzgerald
Application of proteomics to the study of platelet regulatory mechanisms.
Trends in cardiovascular medicine 2004;14(6):207-20.
2004: Katherine M Sheehan; Ronan A Cahill; Gerald T McGreal; C Steele; Michael F Byrne; William O Kirwan; Elaine W Kay; Desmond J Fitzgerald; H Paul Redmond; Frank E Murray
Cyclooxygenase-2 expression in primary human colorectal cancers and bone marrow micrometastases.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2004;36(6):392-7.
2004: Connie E Byrne; Anthony Fitzgerald; Christopher P Cannon; Desmond J Fitzgerald; Denis C Shields
Elevated white cell count in acute coronary syndromes: relationship to variants in inflammatory and thrombotic genes.
BMC medical genetics 2004;5():13.
2004: Maria P Morgan; Linda C Whelan; John D Sallis; Conor J McCarthy; Desmond J Fitzgerald; Geraldine M McCarthy
Basic calcium phosphate crystal-induced prostaglandin E2 production in human fibroblasts: role of cyclooxygenase 1, cyclooxygenase 2, and interleukin-1beta.
Arthritis and rheumatism 2004;50(5):1642-9.
2004: Judith A Coppinger; Gerard Cagney; Sinead Toomey; Thomas Kislinger; Orina Belton; James P McRedmond; Dolores J Cahill; Andrew Emili; Desmond J Fitzgerald; Patricia B Maguire
Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.
Blood 2004;103(6):2096-104.
2004: Dermot Reilly; Deirdre Larkin; Marc Devocelle; Desmond J Fitzgerald; Niamh Moran
Calreticulin-independent regulation of the platelet integrin alphaIIbbeta3 by the KVGFFKR alphaIIb-cytoplasmic motif.
Platelets 2004;15(1):43-54.
2004: James P McRedmond; S D Park; Dermot Reilly; Judith A Coppinger; Patricia B Maguire; D C Shields; Desmond J Fitzgerald
Integration of proteomics and genomics in platelets: a profile of platelet proteins and platelet-specific genes.
Molecular & cellular proteomics : MCP 2004;3(2):133-44.
2003: Orina Belton; Angela Duffy; Sinead Toomey; Desmond J Fitzgerald
Cyclooxygenase isoforms and platelet vessel wall interactions in the apolipoprotein E knockout mouse model of atherosclerosis.
Circulation 2003;108(24):3017-23.
2003: Andrew O Maree; Desmond J Fitzgerald
Glycoprotein IIb/IIIa antagonists in acute coronary syndromes: where are we now?
Seminars in vascular medicine 2003;3(4):385-90.
2003: Michael F Byrne; Joseph F Murphy; Paul corcoran; John C Atherton; Katherine M Sheehan; D Cox; Frank E Murray; Desmond J Fitzgerald
Helicobacter pylori induces cyclooxygenase-1 and cyclooxygenase-2 expression in vascular endothelial cells.
Scandinavian journal of gastroenterology 2003;38(10):1023-30.
2003: Patricia B Maguire; Desmond J Fitzgerald
Platelet proteomics.
Journal of thrombosis and haemostasis : JTH 2003;1(7):1593-601.
2003: Michael F Byrne; Steven W Kerrigan; Paul corcoran; John C Atherton; Frank E Murray; Desmond J Fitzgerald; Dermot M Cox
Helicobacter pylori binds von Willebrand factor and interacts with GPIb to induce platelet aggregation.
Gastroenterology 2003;124(7):1846-54.
2003: Joseph F Murphy; Christopher Steele; Orina Belton; Desmond J Fitzgerald
Induction of cyclooxygenase-1 and -2 modulates angiogenic responses to engagement of alphavbeta3.
British journal of haematology 2003;121(1):157-64.
2003: Marc Devocelle; Brian M McLoughlin; Caroline T Sharkey; Desmond J Fitzgerald; Kevin B Nolan
A convenient parallel synthesis of low molecular weight hydroxamic acids using polymer-supported 1-hydroxybenzotriazole.
Organic & biomolecular chemistry 2003;1(5):850-3.
2003: Orina Belton; Desmond J Fitzgerald
Cyclooxygenase isoforms and atherosclerosis.
Expert reviews in molecular medicine 2003;5(9):1-18.
2003: C M Dooley; Marc Devocelle; Brian M McLoughlin; Kevin B Nolan; Desmond J Fitzgerald; Caroline T Sharkey
A novel family of hydroxamate-based acylating inhibitors of cyclooxygenase.
Molecular pharmacology 2003;63(2):450-5.
2002: Michael F Byrne; Paul corcoran; John C Atherton; Katherine M Sheehan; Frank E Murray; Desmond J Fitzgerald; Joseph F Murphy
Stimulation of adhesion molecule expression by Helicobacter pylori and increased neutrophil adhesion to human umbilical vein endothelial cells.
FEBS letters 2002;532(3):411-4.
2002: Clare Muckian; Anthony Fitzgerald; Anne O'Neill; Anna O'Byrne; Desmond J Fitzgerald; Denis C Shields
Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease.
Blood 2002;100(4):1220-3.
2002: Patricia B Maguire; Kieran Wynne; Donal F Harney; Niaobh O'Donoghue; Gillian Stephens; Desmond J Fitzgerald
Identification of the phosphotyrosine proteome from thrombin activated platelets.
Proteomics 2002;2(6):642-8.
2002: Ronan Curtin; Desmond J Fitzgerald
Pharmacogenetics of antiplatelet drugs.
TheScientificWorldJournal 2002;2():791-800.
2002: Dermot Kenny; Clare Muckian; Desmond J Fitzgerald; Christopher P Cannon; Denis C Shields
Platelet glycoprotein Ib alpha receptor polymorphisms and recurrent ischaemic events in acute coronary syndrome patients.
Journal of thrombosis and thrombolysis 2002;13(1):13-9.
2002: Denis C Shields; A P Fitzgerald; P A O'Neill; Clare Muckian; Dermot Kenny; Barry Moran; Christopher P Cannon; C E Byrne; Desmond J Fitzgerald
The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.
The pharmacogenomics journal 2002;2(3):182-90.
2002: James P McRedmond; Desmond J Fitzgerald
A growing set of platelet-activating bacterial proteins.
Blood 2002;99(1):387-8.
2001: Patrick J Loll; Caroline T Sharkey; S J O'Connor; C M Dooley; E O'Brien; Marc Devocelle; Kevin B Nolan; Barry S Selinsky; Desmond J Fitzgerald
O-acetylsalicylhydroxamic acid, a novel acetylating inhibitor of prostaglandin H2 synthase: structural and functional characterization of enzyme-inhibitor interactions.
Molecular pharmacology 2001;60(6):1407-13.
2001: Fiona O'Connor; Denis C Shields; Anthony Fitzgerald; C P Cannon; E Braunwald; Desmond J Fitzgerald
Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes.
Blood 2001;98(12):3256-60.
2001: J Fullard; R Murphy; Sarah O'Neill; Niamh Moran; B Ottridge; Desmond J Fitzgerald
A Val193Met mutation in GPIIIa results in a GPIIb/IIIa receptor with a constitutively high affinity for a small ligand.
British journal of haematology 2001;115(1):131-9.
2001: Noreen Dowd; M Scully; S R Adderley; A J Cunningham; Desmond J Fitzgerald
Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo.
The Journal of clinical investigation 2001;108(4):585-90.
2001: Joseph F Murphy; Desmond J Fitzgerald
Vascular endothelial growth factor induces cyclooxygenase-dependent proliferation of endothelial cells via the VEGF-2 receptor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(9):1667-9.
2001: A A Shah; Bjarni Thjodleifsson; F E Murray; E Kay; M Barry; Gudmundur Sigthorsson; H Gudjonsson; E Oddsson; AB Price; Desmond J Fitzgerald; Ingvar Bjarnason
Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen.
Gut 2001;48(3):339-46.
2000: Sarah O'Neill; Aisling Robinson; A Deering; M Ryan; Desmond J Fitzgerald; Niamh Moran
The platelet integrin alpha IIbbeta 3 has an endogenous thiol isomerase activity.
The Journal of biological chemistry 2000;275(47):36984-90.
2000: Orina Belton; D Byrne; D Kearney; Austin Leahy; Desmond J Fitzgerald
Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis.
Circulation 2000;102(8):840-5.
2000: Niamh Moran; Patricia A Morateck; A Deering; M Ryan; Robert R Montgomery; Desmond J Fitzgerald; Dermot Kenny
Surface expression of glycoprotein ib alpha is dependent on glycoprotein ib beta: evidence from a novel mutation causing Bernard-Soulier syndrome.
Blood 2000;96(2):532-9.
2000: Fiona O'Connor; Desmond J Fitzgerald; R P Murphy
An automated heteroduplex assay for the Pi(A) polymorphism of glycoprotein IIb/IIIa, multiplexed with two prothrombotic genetic markers.
Thrombosis and haemostasis 2000;83(2):248-52.
2000: R P Murphy; C Donoghue; R J Nallen; M D'Mello; C Regan; Alexander S Whitehead; Desmond J Fitzgerald
Prospective evaluation of the risk conferred by factor V Leiden and thermolabile methylenetetrahydrofolate reductase polymorphisms in pregnancy.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(1):266-70.
1999: Katherine M Sheehan; Kieran Sheahan; Diarmuid P O'Donoghue; F MacSweeney; Ronan Conroy; Desmond J Fitzgerald; Frank E Murray
The relationship between cyclooxygenase-2 expression and colorectal cancer.
JAMA : the journal of the American Medical Association 1999;282(13):1254-7.
1999: A A Shah; F E Murray; Desmond J Fitzgerald
The in vivo assessment of nimesulide cyclooxygenase-2 selectivity.
Rheumatology (Oxford, England) 1999;38 Suppl 1():19-23.
1997: N Delanty; Muredach P Reilly; Domenico Pratico'; John A Lawson; J F McCarthy; Alfred E Wood; S T Ohnishi; Desmond J Fitzgerald; garret fitzgerald
8-epi PGF2 alpha generation during coronary reperfusion. A potential quantitative marker of oxidant stress in vivo.
Circulation 1997;95(11):2492-9.