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Paul FitzGerald

Research Profile

Anatomy

Chemicals & Drugs

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Amino Acid Sequences

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Cataract

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Publications

TOP 3
Daniel N Stewart; Miranda J S Falso; Paul G FitzGerald; Bruce D Hammock; Jozsef Lango; Krishnan P Nambiar; David M Rocke; Bruce A Buchholz
Carbon turnover in the water-soluble protein of the adult human lens.
John F Hess; Atya Aziz; Madhu S Budamagunta; Paul G FitzGerald; John C Voss
Electron paramagnetic resonance analysis of the vimentin tail domain reveals points of order in a largely disordered region and conformational adaptation upon filament assembly.
Atya Aziz; Madhu S Budamagunta; Paul G FitzGerald; John F Hess; Yuanpeng J Huang; Alexandre P Kuzin; Gaetano T Montelione; John C Voss; Rong Xiao; John F Hunt
The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.

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All Publications

2013: Daniel N Stewart; Miranda J S Falso; Paul G FitzGerald; Bruce D Hammock; Jozsef Lango; Krishnan P Nambiar; David M Rocke; Bruce A Buchholz
Carbon turnover in the water-soluble protein of the adult human lens.
Molecular vision 2013;19():463-75.
2013: John F Hess; Atya Aziz; Madhu S Budamagunta; Paul G FitzGerald; John C Voss
Electron paramagnetic resonance analysis of the vimentin tail domain reveals points of order in a largely disordered region and conformational adaptation upon filament assembly.
Protein science : a publication of the Protein Society 2013;22(1):47-55.
2012: Atya Aziz; Madhu S Budamagunta; Paul G FitzGerald; John F Hess; Yuanpeng J Huang; Alexandre P Kuzin; Gaetano T Montelione; John C Voss; Rong Xiao; John F Hunt
The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.
The Journal of biological chemistry 2012;287(34):28349-61.
2012: Jianguo Fan; Paul G FitzGerald; Sanghamitra Mishra; Yingwei Chen; Lijin Dong; Graeme Wistow
A role for γS-crystallin in the organization of actin and fiber cell maturation in the mouse lens.
The FEBS journal 2012;279(16):2892-904.
2012: A Porzig; Lloyd Damon; S Dubois; Robert E Goldsby; R Hawkins; F Hollinger; Katherine K Matthay; M Pampaloni; Paul G FitzGerald
Proteinuria in metastatic pheochromocytoma is associated with an increased risk of Acute Respiratory Distress Syndrome, spontaneously or after therapy with 131I-meta-iodobenzylguanidine (131I-MIBG).
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2012;44(7):539-42.
2012: Susanna S Park; Alan Roth; Bradley Shibata; David G Telander; Ping Zhou; Gerhard Bauer; Sergio Caballero; Paul G FitzGerald; Krisztina I Forward; Maria B Grant; Jeannine McGee; Jan A Nolta
Long-term effects of intravitreal injection of GMP-grade bone-marrow-derived CD34+ cells in NOD-SCID mice with acute ischemia-reperfusion injury.
Investigative ophthalmology & visual science 2012;53(2):986-94.
2012: Karen A Weikel; Qingning Bian; M Andrea Caceres; Paul G FitzGerald; James T Handa; Fu Shang; Alan W Stitt; Allen Taylor
Natural history of age-related retinal lesions that precede AMD in mice fed high or low glycemic index diets.
Investigative ophthalmology & visual science 2012;53(2):622-32.
2011: Yanrong Shi; Huan Wang; Alicia B De Maria; Paul G FitzGerald; Richard T Mathias; Steven Bassnett
Further analysis of the lens phenotype in Lim2-deficient mice.
Investigative ophthalmology & visual science 2011;52(10):7332-9.
2011: John J Castorino; Paul G FitzGerald; Shannon M Gallagher-Colombo; Barbara Kloeckener-Gruissem; Alex V Levin; Eric Ostertag; Jessica Polishook; Nancy J Philp
Juvenile cataract-associated mutation of solute carrier SLC16A12 impairs trafficking of the protein to the plasma membrane.
Investigative ophthalmology & visual science 2011;52(9):6774-84.
2011: DS Fudge; John V McCuaig; Shannon Van Stralen; John F Hess; Huan Wang; Richard T Mathias; Paul G FitzGerald
Intermediate filaments regulate tissue size and stiffness in the murine lens.
Investigative ophthalmology & visual science 2011;52(6):3860-7.
2010: Atya Aziz; John F Hess; Madhu S Budamagunta; John C Voss; Paul G FitzGerald
Site-directed spin labeling and electron paramagnetic resonance determination of vimentin head domain structure.
The Journal of biological chemistry 2010;285(20):15278-85.
2009: Atya Aziz; John F Hess; Madhu S Budamagunta; Paul G FitzGerald; John C Voss
Head and rod 1 interactions in vimentin: identification of contact sites, structure, and changes with phosphorylation using site-directed spin labeling and electron paramagnetic resonance.
The Journal of biological chemistry 2009;284(11):7330-8.
2009: S H Lindstrom; N Nacsa; Thomas N Blankenship; Paul G FitzGerald; C Weller; D I Vaney; Martin Wilson
Distribution and structure of efferent synapses in the chicken retina.
Visual neuroscience 2009;26(2):215-26.
2009: Kyoung-hye Yoon; Paul G FitzGerald
Periplakin interactions with lens intermediate and beaded filaments.
Investigative ophthalmology & visual science 2009;50(3):1283-9.
2009: Paul G FitzGerald
Lens intermediate filaments.
Experimental eye research 2009;88(2):165-72.
2008: Josh T Pittenger; John F Hess; Madhu S Budamagunta; John C Voss; Paul G FitzGerald
Identification of phosphorylation-induced changes in vimentin intermediate filaments by site-directed spin labeling and electron paramagnetic resonance.
Biochemistry 2008;47(41):10863-70.
2008: Kyoung-Hye Yoon; Thomas N Blankenship; Bradley Shibata; Paul G FitzGerald
Resisting the effects of aging: a function for the fiber cell beaded filament.
Investigative ophthalmology & visual science 2008;49(3):1030-6.
2007: Joshua T Pittenger; John F Hess; Paul G FitzGerald
Identifying the role of specific motifs in the lens fiber cell specific intermediate filament phakosin.
Investigative ophthalmology & visual science 2007;48(11):5132-41.
2007: Jens O Lagerstedt; Giorgio Cavigiolio; Linda M Roberts; Hyun-Seok Hong; Lee-Way Jin; Paul G FitzGerald; Michael N Oda; John C Voss
Mapping the structural transition in an amyloidogenic apolipoprotein A-I.
Biochemistry 2007;46(34):9693-9.
2007: John F Hess; Paul G FitzGerald
Treatment of keratin intermediate filaments with sulfur mustard analogs.
Biochemical and biophysical research communications 2007;359(3):616-21.
2007: Thomas N Blankenship; Linsey Bradshaw; Bradley Shibata; Paul G FitzGerald
Structural specializations emerging late in mouse lens fiber cell differentiation.
Investigative ophthalmology & visual science 2007;48(7):3269-76.
2007: Madhu Budamagunta; John Hess; Paul G FitzGerald; John C Voss
Describing the structure and assembly of protein filaments by EPR spectroscopy of spin-labeled side chains.
Cell biochemistry and biophysics 2007;48(1):45-53.
2006: John F Hess; Madhu S Budamagunta; Rebecca L Shipman; Paul G FitzGerald; John C Voss
Characterization of the linker 2 region in human vimentin using site-directed spin labeling and electron paramagnetic resonance.
Biochemistry 2006;45(39):11737-43.
2005: John F Hess; Madhu S Budamagunta; Paul G FitzGerald; John C Voss
Characterization of structural changes in vimentin bearing an epidermolysis bullosa simplex-like mutation using site-directed spin labeling and electron paramagnetic resonance.
The Journal of biological chemistry 2005;280(3):2141-6.
2004: John F Hess; Madhu S Budamagunta; John C Voss; Paul G FitzGerald
Structural characterization of human vimentin rod 1 and the sequencing of assembly steps in intermediate filament formation in vitro using site-directed spin labeling and electron paramagnetic resonance.
The Journal of biological chemistry 2004;279(43):44841-6.
2004: Azita Alizadeh; John Clark; Teri Seeberger Greiling; John Hess; Thomas N Blankenship; Paul G FitzGerald
Characterization of a mutation in the lens-specific CP49 in the 129 strain of mouse.
Investigative ophthalmology & visual science 2004;45(3):884-91.
2004: Teri Seeberger Greiling; Y Matsumoto; A Alizadeh; Paul G FitzGerald; J I Clark
Digital image capture and quantification of subtle lens opacities in rodents.
Journal of biomedical optics 2004;9(1):116-20.
2003: Azita Alizadeh; John Clark; Teri Seeberger Greiling; John Hess; Thomas N Blankenship; Paul G FitzGerald
Targeted deletion of the lens fiber cell-specific intermediate filament protein filensin.
Investigative ophthalmology & visual science 2003;44(12):5252-8.
2003: Daryle Joseph Depianto; Thomas N Blankenship; John F Hess; Paul G FitzGerald
Analysis of non-crystallin lens fiber cell gene expression in c-Maf -/- mice.
Molecular vision 2003;9():288-94.
2003: Daryle Joseph Depianto; John F Hess; Thomas N Blankenship; Paul G FitzGerald
Isolation and characterization of the human CP49 gene promoter.
Investigative ophthalmology & visual science 2003;44(1):235-43.
2002: Azita Alizadeh; John I Clark; Teri Seeberger Greiling; John Hess; Thomas N Blankenship; Andrew P Spicer; Paul G FitzGerald
Targeted genomic deletion of the lens-specific intermediate filament protein CP49.
Investigative ophthalmology & visual science 2002;43(12):3722-7.
2002: John F Hess; John C Voss; Paul G FitzGerald
Real-time observation of coiled-coil domains and subunit assembly in intermediate filaments.
The Journal of biological chemistry 2002;277(38):35516-22.
2002: Ivan R Schwab; Carlton K Yuen; Nedim C Buyukmihci; Thomas N Blankenship; Paul G FitzGerald
Evolution of the tapetum.
Transactions of the American Ophthalmological Society 2002;100():187-99; discussion 199-200.
2002: Peter A Binkley; John Hess; Jodi Casselman; Paul G FitzGerald
Unexpected variation in unique features of the lens-specific type I cytokeratin CP49.
Investigative ophthalmology & visual science 2002;43(1):225-35.
2001: John F Hess; Jodi Casselman; Paul G FitzGerald
Modified version of pACT-2 that simplifies cloning with NdeI.
BioTechniques 2001;30(6):1204, 1207.
2001: Thomas N Blankenship; John F Hess; Paul G FitzGerald
Development- and differentiation-dependent reorganization of intermediate filaments in fiber cells.
Investigative ophthalmology & visual science 2001;42(3):735-42.
2001: Ivan R Schwab; V Ho; A Roth; Thomas N Blankenship; Paul G FitzGerald
Evolutionary attempts at 4 eyes in vertebrates.
Transactions of the American Ophthalmological Society 2001;99():145-56; discussion 156-7.
2000: M Yoshikawa; K Anderson; H Sakaguchi; John G Flannery; Paul G FitzGerald; Andrew T Ishida
Voltage-gated Na+ channel EOIII-segment-like immunoreactivity in fish retinal ganglion cells.
Visual neuroscience 2000;17(4):647-55.
2000: Petra Jakobs; John F Hess; Paul G FitzGerald; Patricia L Kramer; Richard G Weleber; Michael Litt
Autosomal-dominant congenital cataract associated with a deletion mutation in the human beaded filament protein gene BFSP2.
American journal of human genetics 2000;66(4):1432-6.
2000: Yvette P Conley; D Erturk; A Keverline; Tammy S Mah; Annahita Keravala; L R Barnes; A Bruchis; John F Hess; Paul G FitzGerald; Daniel E Weeks; Robert E Ferrell; Michael B Gorin
A juvenile-onset, progressive cataract locus on chromosome 3q21-q22 is associated with a missense mutation in the beaded filament structural protein-2.
American journal of human genetics 2000;66(4):1426-31.
1998: John F Hess; Paul G FitzGerald
Protection of a restriction enzyme from heat inactivation by [alpha]-crystallin.
Molecular vision 1998;4():29.
1998: John F Hess; Jodi Casselman; A P Kong; Paul G FitzGerald
Primary sequence, secondary structure, gene structure, and assembly properties suggests that the lens-specific cytoskeletal protein filensin represents a novel class of intermediate filament protein.
Experimental eye research 1998;66(5):625-44.
1996: John F Hess; Paul G FitzGerald
Lack of DNase I mRNA sequences in murine lenses.
Molecular vision 1996;2():8.
1996: John F Hess; J T Casselman; Paul G FitzGerald
Gene structure and cDNA sequence identify the beaded filament protein CP49 as a highly divergent type I intermediate filament protein.
The Journal of biological chemistry 1996;271(12):6729-35.
1995: Aileen Sandilands; Alan R Prescott; Aileen M Hutcheson; Roy A Quinlan; J T Casselman; Paul G FitzGerald
Filensin is proteolytically processed during lens fiber cell differentiation by multiple independent pathways.
European journal of cell biology 1995;67(3):238-53.
1995: Aileen Sandilands; Alan R Prescott; J M Carter; Aileen M Hutcheson; Roy A Quinlan; J Richards; Paul G FitzGerald
Vimentin and CP49/filensin form distinct networks in the lens which are independently modulated during lens fibre cell differentiation.
Journal of cell science 1995;108 ( Pt 4)():1397-406.
1995: John F Hess; J T Casselman; Paul G FitzGerald
Chromosomal locations of the genes for the beaded filament proteins CP 115 and CP 47.
Current eye research 1995;14(1):11-8.
1994: John F Hess; J T Casselman; Paul G FitzGerald
Nucleotide sequence of the bovine vimentin-encoding cDNA.
Gene 1994;140(2):257-9.
1993: PA Grimes; Jack Favor; Brigitte Koeberlein; W K Silvers; Paul G FitzGerald; Dwight Stambolian
Lens development in a dominant X-linked congenital cataract of the mouse.
Experimental eye research 1993;57(5):587-94.
1993: Fotini Gounari; A Merdes; R Quinlan; J Hess; Paul G FitzGerald; Christos Ouzounis; Spyros D Georgatos
Bovine filensin possesses primary and secondary structure similarity to intermediate filament proteins.
The Journal of cell biology 1993;121(4):847-53.
1993: John F Hess; J T Casselman; Paul G FitzGerald
cDNA analysis of the 49 kDa lens fiber cell cytoskeletal protein: a new, lens-specific member of the intermediate filament family?
Current eye research 1993;12(1):77-88.
1991: Paul G FitzGerald; J Casselman
Immunologic conservation of the fiber cell beaded filament.
Current eye research 1991;10(5):471-8.
1991: Paul G FitzGerald; D Graham
Ultrastructural localization of alpha A-crystallin to the bovine lens fiber cell cytoskeleton.
Current eye research 1991;10(5):417-36.
1990: Paul G FitzGerald
Methods for the circumvention of problems associated with the study of the ocular lens plasma membrane-cytoskeleton complex.
Current eye research 1990;9(11):1083-97.
1990: Paul G FitzGerald; J Casselman
Discrimination between the lens fiber cell 115 kd cytoskeletal protein and alpha-actinin.
Current eye research 1990;9(9):873-82.
1989: Charles Thirkill; Paul G FitzGerald; Robert Sergott; A M Roth; N K Tyler; John L Keltner
Cancer-associated retinopathy (CAR syndrome) with antibodies reacting with retinal, optic-nerve, and cancer cells.
The New England journal of medicine 1989;321(23):1589-94.
1989: Paul G FitzGerald; W Gottlieb
The Mr 115 kd fiber cell-specific protein is a component of the lens cytoskeleton.
Current eye research 1989;8(8):801-11.
1988: Paul G FitzGerald
Age-related changes in a fiber cell-specific extrinsic membrane protein.
Current eye research 1988;7(12):1255-62.
1988: Paul G FitzGerald
Immunochemical characterization of a Mr 115 lens fiber cell-specific extrinsic membrane protein.
Current eye research 1988;7(12):1243-53.
1987: Paul G FitzGerald
Main intrinsic polypeptide proteolysis and fiber cell membrane domains.
Investigative ophthalmology & visual science 1987;28(5):795-805.
1986: Paul G FitzGerald; D A Goodenough
Rat lens cultures: MIP expression and domains of intercellular coupling.
Investigative ophthalmology & visual science 1986;27(5):755-71.
1985: Paul G FitzGerald; D Bok; J Horwitz
The distribution of the main intrinsic membrane polypeptide in ocular lens.
Current eye research 1985;4(11):1203-18.
1983: Paul G FitzGerald; D Bok; J Horwitz
Immunocytochemical localization of the main intrinsic polypeptide (MIP) in ultrathin frozen sections of rat lens.
The Journal of cell biology 1983;97(5 Pt 1):1491-9.