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Hans-Dieter Flad

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Hans-Dieter Flad; Ernst Brandt
Platelet-derived chemokines: pathophysiology and therapeutic aspects.
Birgit I Schenk; Frank Petersen; Hans-Dieter Flad; Ernst Brandt
Platelet-derived chemokines CXC chemokine ligand (CXCL)7, connective tissue-activating peptide III, and CXCL4 differentially affect and cross-regulate neutrophil adhesion and transendothelial migration.
Antje Blumenthal; Stefan Ehlers; Martin Ernst; Hans-Dieter Flad; Norbert Reiling
Control of mycobacterial replication in human macrophages: roles of extracellular signal-regulated kinases 1 and 2 and p38 mitogen-activated protein kinase pathways.

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All Publications

2010: Hans-Dieter Flad; Ernst Brandt
Platelet-derived chemokines: pathophysiology and therapeutic aspects.
Cellular and molecular life sciences : CMLS 2010;67(14):2363-86.
2002: Birgit I Schenk; Frank Petersen; Hans-Dieter Flad; Ernst Brandt
Platelet-derived chemokines CXC chemokine ligand (CXCL)7, connective tissue-activating peptide III, and CXCL4 differentially affect and cross-regulate neutrophil adhesion and transendothelial migration.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(5):2602-10.
2002: Antje Blumenthal; Stefan Ehlers; Martin Ernst; Hans-Dieter Flad; Norbert Reiling
Control of mycobacterial replication in human macrophages: roles of extracellular signal-regulated kinases 1 and 2 and p38 mitogen-activated protein kinase pathways.
Infection and immunity 2002;70(9):4961-7.
2002: Jens Fleischer; Evelin Grage-Griebenow; Brigitte Kasper; Holger Heine; Martin Ernst; Ernst Brandt; Hans-Dieter Flad; Frank Petersen
Platelet factor 4 inhibits proliferation and cytokine release of activated human T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(2):770-7.
2002: Malgorzata Bzowska; Krzysztof Guzik; Katarzyna Barczyk; Martin Ernst; Hans-Dieter Flad; Juliusz Pryjma
Increased IL-10 production during spontaneous apoptosis of monocytes.
European journal of immunology 2002;32(7):2011-20.
2002: Franziska Schwartzkopff; Ernst Brandt; Frank Petersen; Hans-Dieter Flad; Lothar Bock; Andreas Ludwig
The CXC chemokine NAP-2 mediates differential heterologous desensitization of neutrophil effector functions elicited by platelet-activating factor.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2002;22(2):257-67.
2001: Ulrike Seitzer; K Kayser; Hanni Höhn; Peter Entzian; H H Wacker; S Ploetz; Hans-Dieter Flad; Johannes Gerdes; Markus J Maeurer
Reduced T-cell receptor CD3zeta-chain protein and sustained CD3epsilon expression at the site of mycobacterial infection.
Immunology 2001;104(3):269-77.
2001: Norbert Reiling; Antje Blumenthal; Hans-Dieter Flad; Martin Ernst; Stefan Ehlers
Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(6):3339-45.
2001: D Muhvić; Volker El-Samalouti; Hans-Dieter Flad; B Radosević-Stasić; Daniel Rukavina
The involvement of CD14 in the activation of human monocytes by peptidoglycan monomers.
Mediators of inflammation 2001;10(3):155-62.
2001: Jaroslaw Baran; Kazimierz Weglarczyk; M Mysiak; Krzysztof Guzik; Martin Ernst; Hans-Dieter Flad; Juliusz Pryjma
Fas (CD95)-Fas ligand interactions are responsible for monocyte apoptosis occurring as a result of phagocytosis and killing of Staphylococcus aureus.
Infection and immunity 2001;69(3):1287-97.
2001: Evelin Grage-Griebenow; Hans-Dieter Flad; Martin Ernst
Heterogeneity of human peripheral blood monocyte subsets.
Journal of leukocyte biology 2001;69(1):11-20.
2001: Evelin Grage-Griebenow; Rainer Zawatzky; Helga Kahlert; Lore Brade; Hans-Dieter Flad; Martin Ernst
Identification of a novel dendritic cell-like subset of CD64(+) / CD16(+) blood monocytes.
European journal of immunology 2001;31(1):48-56.
2001: S G Plötz; Arnd Lentschat; H Behrendt; W Plötz; Lutz Hamann; J Ring; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
The interaction of human peripheral blood eosinophils with bacterial lipopolysaccharide is CD14 dependent.
Blood 2001;97(1):235-41.
2000: Artur J Ulmer; Hans-Dieter Flad; T Rietschel; T Mattern
Induction of proliferation and cytokine production in human T lymphocytes by lipopolysaccharide (LPS).
Toxicology 2000;152(1-3):37-45.
2000: Ulf Greinert; MW Schlaak; Sabine Rüsch-Gerdes; Hans-Dieter Flad; Martin Ernst
Low in vitro production of interferon-gamma and tumor necrosis factor-alpha in HIV-seronegative patients with pulmonary disease caused by nontuberculous mycobacteria.
Journal of clinical immunology 2000;20(6):445-52.
2000: JE Ehlert; Andreas Ludwig; T A Grimm; Buko Lindner; Hans-Dieter Flad; Ernst Brandt
Down-regulation of neutrophil functions by the ELR(+) CXC chemokine platelet basic protein.
Blood 2000;96(9):2965-72.
2000: Ernst Brandt; A Ludwig; F Petersen; Hans-Dieter Flad
Platelet-derived CXC chemokines: old players in new games.
Immunological reviews 2000;177():204-16.
2000: Frank Petersen; Dorothe Spillmann; Barbara Scheuerer; Jens Fleischer; Hans-Dieter Flad; Ernst Brandt
Is platelet factor-4 a chemokine?
European cytokine network 2000;11(3):506-7.
2000: Andreas Böhle; A Thanhäuser; M Ernst; Hans-Dieter Flad; Sabine Rüsch-Gerdes; Dieter Jocham; Artur J Ulmer
Reduction of side effects of intravesical therapy with bacille Calmette-Guérin by pentoxifylline?--an in vitro approach.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;31 Suppl 3():S101-5.
2000: Sven Brandau; Andreas Böhle; A Thanhäuser; Martin Ernst; T Mattern; Artur J Ulmer; Hans-Dieter Flad
In vitro generation of bacillus Calmette-Guérin-activated killer cells.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;31 Suppl 3():S94-S100.
2000: Sven Brandau; Henrik Suttmann; Josef Riemensberger; Ulrike Seitzer; J Arnold; Christoph Durek; Dieter Jocham; Hans-Dieter Flad; Andreas Böhle
Perforin-mediated lysis of tumor cells by Mycobacterium bovis Bacillus Calmette-Guérin-activated killer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3729-38.
2000: Sven Brandau; Henrik Suttmann; Hans-Dieter Flad; Dieter Jocham; Andreas Böhle
Killing of Fas ligand-resistant renal carcioma cells by interleukin-2- and BCG-activated effector cells.
Cancer immunology, immunotherapy : CII 2000;49(7):369-76.
2000: Andreas Ludwig; JE Ehlert; Hans-Dieter Flad; Ernst Brandt
Identification of distinct surface-expressed and intracellular CXC-chemokine receptor 2 glycoforms in neutrophils: N-glycosylation is essential for maintenance of receptor surface expression.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(2):1044-52.
2000: Evelin Grage-Griebenow; Hans-Dieter Flad; Martin Ernst; Malgorzata Bzowska; J Skrzeczyñska; Juliusz Pryjma
Human MO subsets as defined by expression of CD64 and CD16 differ in phagocytic activity and generation of oxygen intermediates.
Immunobiology 2000;202(1):42-50.
2000: Ernst Brandt; Frank Petersen; Andreas Ludwig; JE Ehlert; Lothar Bock; Hans-Dieter Flad
The beta-thromboglobulins and platelet factor 4: blood platelet-derived CXC chemokines with divergent roles in early neutrophil regulation.
Journal of leukocyte biology 2000;67(4):471-8.
2000: Barbara Scheuerer; Martin Ernst; I Dürrbaum-Landmann; Jens Fleischer; Evelin Grage-Griebenow; Ernst Brandt; Hans-Dieter Flad; Frank Petersen
The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages.
Blood 2000;95(4):1158-66.
2000: Volker El-Samalouti; Lutz Hamann; Hans-Dieter Flad; Artur J Ulmer
The biology of endotoxin.
Methods in molecular biology (Clifton, N.J.) 2000;145():287-309.
2000: Lutz Hamann; Ralf R Schumann; Hans-Dieter Flad; Lore Brade; Ernst Th Rietschel; Artur J Ulmer
Binding of lipopolysaccharide (LPS) to CHO cells does not correlate with LPS-induced NF-kappaB activation.
European journal of immunology 2000;30(1):211-6.
1999: Frank Petersen; Lothar Bock; Hans-Dieter Flad; Ernst Brandt
Platelet factor 4-induced neutrophil-endothelial cell interaction: involvement of mechanisms and functional consequences different from those elicited by interleukin-8.
Blood 1999;94(12):4020-8.
1999: Christoph Durek; Sven Brandau; Artur J Ulmer; Hans-Dieter Flad; Dieter Jocham; Andreas Böhle
Bacillus-Calmette-Guérin (BCG) and 3D tumors: an in vitro model for the study of adhesion and invasion.
The Journal of urology 1999;162(2):600-5.
1999: C Swider; Leonhard Schnittger; K Bogunia-Kubik; Johannes Gerdes; Hans-Dieter Flad; A Lange; Ulrike Seitzer
TNF-alpha and HLA-DR genotyping as potential prognostic markers in pulmonary sarcoidosis.
European cytokine network 1999;10(2):143-6.
1999: Arnd Lentschat; Volker El-Samalouti; J Schletter; Shoichi Kusumoto; Lore Brade; Ernst Th Rietschel; J Gerdes; Martin Ernst; Hans-Dieter Flad; Artur J Ulmer
The internalization time course of a given lipopolysaccharide chemotype does not correspond to its activation kinetics in monocytes.
Infection and immunity 1999;67(5):2515-21.
1999: Volker El-Samalouti; J Schletter; I Chyla; Arnd Lentschat; Uwe Mamat; Lore Brade; Hans-Dieter Flad; Artur J Ulmer; Lutz Hamann
Identification of the 80-kDa LPS-binding protein (LMP80) as decay-accelerating factor (DAF, CD55).
FEMS immunology and medical microbiology 1999;23(3):259-69.
1999: T Mattern; G Girroleit; Hans-Dieter Flad; Ernst Th Rietschel; Artur J Ulmer
CD34(+) hematopoietic stem cells exert accessory function in lipopolysaccharide-induced T cell stimulation and CD80 expression on monocytes.
The Journal of experimental medicine 1999;189(4):693-700.
1999: Hans-Dieter Flad; Evelin Grage-Griebenow; Frank Petersen; Barbara Scheuerer; Ernst Brandt; Jaroslaw Baran; Juliusz Pryjma; Martin Ernst
The role of cytokines in monocyte apoptosis.
Pathobiology : journal of immunopathology, molecular and cellular biology 1999;67(5-6):291-3.
1998: Evelin Grage-Griebenow; I Dürrbaum-Landmann; Juliusz Pryjma; Harald Loppnow; Hans-Dieter Flad; Martin Ernst
Apoptosis in monocytes.
European cytokine network 1998;9(4):699-700.
1998: Harald Loppnow; Karl Werdan; G Reuter; Hans-Dieter Flad
The interleukin-1 and interleukin-1 converting enzyme families in the cardiovascular system.
European cytokine network 1998;9(4):675-80.
1998: JE Ehlert; J Gerdes; Hans-Dieter Flad; Ernst Brandt
Novel C-terminally truncated isoforms of the CXC chemokine beta-thromboglobulin and their impact on neutrophil functions.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4975-82.
1998: Frank Petersen; Lothar Bock; Hans-Dieter Flad; Ernst Brandt
A chondroitin sulfate proteoglycan on human neutrophils specifically binds platelet factor 4 and is involved in cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):4347-55.
1998: Hans-Dieter Flad; Evelin Grage-Griebenow; Barbara Scheuerer; I Dürrbaum-Landmann; Frank Petersen; Ernst Brandt; Jens Fleischer; Jaroslaw Baran; Juliusz Pryjma; Martin Ernst
The role of cytokines in monocyte apoptosis.
Research in immunology 1998;149(7-8):733-6.
1998: Lutz Hamann; Volker El-Samalouti; Artur J Ulmer; Hans-Dieter Flad; Ernst Th Rietschel
Components of gut bacteria as immunomodulators.
International journal of food microbiology 1998;41(2):141-54.
1998: Ulrike Seitzer; D Scheel-Toellner; T Mattern; H Haas; Hans-Dieter Flad; Johannes Gerdes
Staining pattern of seven monoclonal anti-CD26 antibodies in leprosy: implications for the use of CD26 as a surrogate marker of a human Th1-like reaction.
Virchows Archiv : an international journal of pathology 1998;432(4):343-7.
1998: T Mattern; Hans-Dieter Flad; Lore Brade; Ernst Th Rietschel; Artur J Ulmer
Stimulation of human T lymphocytes by LPS is MHC unrestricted, but strongly dependent on B7 interactions.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3412-8.
1998: T Mattern; C Reich; Uwe Schönbeck; S Ansorge; H U Demuth; Harald Loppnow; Artur J Ulmer; Hans-Dieter Flad
CD26 (dipeptidyl peptidase i.v.) on human T lymphocytes does not mediate adhesion of these cells to endothelial cells or fibroblasts.
Immunobiology 1998;198(4):465-75.
1998: T Mattern; Hans-Dieter Flad; Artur J Ulmer
Stimulation of human T lymphocytes by lipopolysaccaride (LPS) in the presence of autologous and heterologous monocytes.
Progress in clinical and biological research 1998;397():243-54.
1998: Sunna Hauschildt; A J Ulmer; Hans-Dieter Flad; T Heyden; Holger Heine
ADP-ribosylation: role in LPS-induced phosphorylation of two cytosolic proteins (p36/38) in monocytes.
Progress in clinical and biological research 1998;397():147-55.
1998: Ernst Th Rietschel; J Schletter; B Weidemann; Volker El-Samalouti; T Mattern; Ulrich Zähringer; Ulrich Seydel; Helmut Brade; Hans-Dieter Flad; Shoichi Kusumoto; D Gupta; Roman Dziarski; Artur J Ulmer
Lipopolysaccharide and peptidoglycan: CD14-dependent bacterial inducers of inflammation.
Microbial drug resistance (Larchmont, N.Y.) 1998;4(1):37-44.
1998: Harald Loppnow; R Bil; S Hirt; Uwe Schönbeck; Mona Herzberg; Karl Werdan; Ernst Th Rietschel; Ernst Brandt; Hans-Dieter Flad
Platelet-derived interleukin-1 induces cytokine production, but not proliferation of human vascular smooth muscle cells.
Blood 1998;91(1):134-41.
1997: Sunna Hauschildt; C Schwarz; Holger Heine; A J Ulmer; Hans-Dieter Flad; E T Rietschel; O N Jensen; M Mann
Actin: a target of lipopolysaccharide-induced phosphorylation in human monocytes.
Biochemical and biophysical research communications 1997;241(3):670-4.
1997: Volker El-Samalouti; J Schletter; Helmut Brade; Lore Brade; Shoichi Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Detection of lipopolysaccharide (LPS)-binding membrane proteins by immuno-coprecipitation with LPS and anti-LPS antibodies.
European journal of biochemistry / FEBS 1997;250(2):418-24.
1997: Andreas Ludwig; Frank Petersen; S Zahn; Otto Götze; Jens Schröder; Hans-Dieter Flad; Ernst Brandt
The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2.
Blood 1997;90(11):4588-97.
1997: Ulrike Seitzer; C Swider; F Stüber; K Suchnicki; A Lange; E Richter; Peter Zabel; Joachim Müller-Quernheim; Hans-Dieter Flad; Johannes Gerdes
Tumour necrosis factor alpha promoter gene polymorphism in sarcoidosis.
Cytokine 1997;9(10):787-90.
1997: Evelin Grage-Griebenow; Jaroslaw Baran; Harald Loppnow; M Los; Martin Ernst; Hans-Dieter Flad; Juliusz Pryjma
An Fc gamma receptor I (CD64)-negative subpopulation of human peripheral blood monocytes is resistant to killing by antigen-activated CD4-positive cytotoxic T cells.
European journal of immunology 1997;27(9):2358-65.
1997: Uwe Schönbeck; F Mach; J Y Bonnefoy; Harald Loppnow; Hans-Dieter Flad; Peter Libby
Ligation of CD40 activates interleukin 1beta-converting enzyme (caspase-1) activity in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1beta.
The Journal of biological chemistry 1997;272(31):19569-74.
1997: Ulrike Seitzer; D Scheel-Toellner; Kai-Michael Toellner; Norbert Reiling; H Haas; J Galle; Hans-Dieter Flad; Johannes Gerdes
Properties of multinucleated giant cells in a new in vitro model for human granuloma formation.
The Journal of pathology 1997;182(1):99-105.
1997: Uwe Schönbeck; Mona Herzberg; A Petersen; Claudia Wohlenberg; Johannes Gerdes; Hans-Dieter Flad; Harald Loppnow
Human vascular smooth muscle cells express interleukin-1beta-converting enzyme (ICE), but inhibit processing of the interleukin-1beta precursor by ICE.
The Journal of experimental medicine 1997;185(7):1287-94.
1997: Christoph Durek; I Schäfer; H Braasch; Artur J Ulmer; M Ernst; Hans-Dieter Flad; Dieter Jocham; Andreas Böhle
Effects of colony-stimulating factors on cellular cytotoxicity.
Cancer immunology, immunotherapy : CII 1997;44(1):35-40.
1997: B Weidemann; J Schletter; Roman Dziarski; Shoichi Kusumoto; Felix Stelter; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes.
Infection and immunity 1997;65(3):858-64.
1997: Hans-Dieter Flad; L Härter; Frank Petersen; JE Ehlert; Andreas Ludwig; Lothar Bock; Ernst Brandt
Regulation of neutrophil activation by proteolytic processing of platelet-derived alpha-chemokines.
Advances in experimental medicine and biology 1997;421():223-30.
1997: Ulrike Seitzer; D Scheel-Toellner; M Hahn; G Heinemann; T Mattern; Hans-Dieter Flad; Johannes Gerdes
Comparative study of CD26 as a Th1-like and CD30 as a potential Th2-like operational marker in leprosy.
Advances in experimental medicine and biology 1997;421():217-21.
1997: Sunna Hauschildt; P Scheipers; W Bessler; K Schwarz; A Ullmer; Hans-Dieter Flad; Holger Heine
Role of ADP-ribosylation in activated monocytes/macrophages.
Advances in experimental medicine and biology 1997;419():249-52.
1996: Andra B Schromm; Klaus Brandenburg; Ernst Th Rietschel; Hans-Dieter Flad; SF Carroll; Ulrich Seydel
Lipopolysaccharide-binding protein mediates CD14-independent intercalation of lipopolysaccharide into phospholipid membranes.
FEBS letters 1996;399(3):267-71.
1996: J Fleischer; E Soeth; N Reiling; Evelin Grage-Griebenow; Hans-Dieter Flad; Martin Ernst
Differential expression and function of CD80 (B7-1) and CD86 (B7-2) on human peripheral blood monocytes.
Immunology 1996;89(4):592-8.
1996: Otto Holst; Artur J Ulmer; Helmut Brade; Hans-Dieter Flad; Ernst Th Rietschel
Biochemistry and cell biology of bacterial endotoxins.
FEMS immunology and medical microbiology 1996;16(2):83-104.
1996: I Dürrbaum-Landmann; J Gercken; Hans-Dieter Flad; Martin Ernst
Effect of in vitro infection of human monocytes with low numbers of Mycobacterium tuberculosis bacteria on monocyte apoptosis.
Infection and immunity 1996;64(12):5384-9.
1996: Jaroslaw Baran; Krzysztof Guzik; W Hryniewicz; Martin Ernst; Hans-Dieter Flad; Juliusz Pryjma
Apoptosis of monocytes and prolonged survival of granulocytes as a result of phagocytosis of bacteria.
Infection and immunity 1996;64(10):4242-8.
1996: R Kröncke; Harald Loppnow; Hans-Dieter Flad; Johannes Gerdes
Human follicular dendritic cells and vascular cells produce interleukin-7: a potential role for interleukin-7 in the germinal center reaction.
European journal of immunology 1996;26(10):2541-4.
1996: Evelin Grage-Griebenow; Hans-Dieter Flad; Martin Ernst
Fc gamma receptor I (CD64)-negative human monocytes are potent accessory cells in viral antigen-induced T cell activation and exhibit high IFN-alpha-producing capacity.
Journal of leukocyte biology 1996;60(3):389-96.
1996: Kai-Michael Toellner; D Scheel-Toellner; Ulrike Seitzer; R Sprenger; L Trümper; C Schlüter; Hans-Dieter Flad; Johannes Gerdes
The use of reverse transcription polymerase chain reaction to analyse large numbers of mRNA species from a single cell.
Journal of immunological methods 1996;191(1):71-5.
1996: N Reiling; R Kröncke; Artur J Ulmer; Johannes Gerdes; Hans-Dieter Flad; Sunna Hauschildt
Nitric oxide synthase: expression of the endothelial, Ca2+/calmodulin-dependent isoform in human B and T lymphocytes.
European journal of immunology 1996;26(3):511-6.
1996: Frank Petersen; Andreas Ludwig; Hans-Dieter Flad; Ernst Brandt
TNF-alpha renders human neutrophils responsive to platelet factor 4. Comparison of PF-4 and IL-8 reveals different activity profiles of the two chemokines.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(5):1954-62.
1996: Ernst Th Rietschel; Helmut Brade; Otto Holst; Lore Brade; Sven Müller-Loennies; Uwe Mamat; Ulrich Zähringer; F Beckmann; Ulrich Seydel; Klaus Brandenburg; Artur J Ulmer; T Mattern; Holger Heine; J Schletter; Harald Loppnow; Uwe Schönbeck; Hans-Dieter Flad; Sunna Hauschildt; U F Schade; F Di Padova; S Kusumoto; Ralf R Schumann
Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification.
Current topics in microbiology and immunology 1996;216():39-81.
1996: Michael Duchrow; C Schlüter; C Wohlenberg; Hans-Dieter Flad; Johannes Gerdes
Molecular characterization of the gene locus of the human cell proliferation-associated nuclear protein defined by monoclonal antibody Ki-67.
Cell proliferation 1996;29(1):1-12.
1996: Elvira Richter; Ulf Greinert; D Kirsten; Sabine Rüsch-Gerdes; C Schlüter; Michael Duchrow; J Galle; H Magnussen; MW Schlaak; Hans-Dieter Flad; Johannes Gerdes
Assessment of mycobacterial DNA in cells and tissues of mycobacterial and sarcoid lesions.
American journal of respiratory and critical care medicine 1996;153(1):375-80.
1995: Holger Heine; Artur J Ulmer; Hans-Dieter Flad; Sunna Hauschildt
Lipopolysaccharide-induced change of phosphorylation of two cytosolic proteins in human monocytes is prevented by inhibitors of ADP-ribosylation.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):4899-908.
1995: D Scheel-Toellner; E Richter; Kai-Michael Toellner; N Reiling; H H Wacker; Hans-Dieter Flad; Johannes Gerdes
CD26 expression in leprosy and other granulomatous diseases correlates with the production of interferon-gamma.
Laboratory investigation; a journal of technical methods and pathology 1995;73(5):685-90.
1995: R Sprenger; Kai-Michael Toellner; C Schmetz; Wolfgang Lüke; C Stahl-Hennig; Martin Ernst; Gerhard Hunsmann; H Schmitz; Hans-Dieter Flad; Johannes Gerdes
Follicular dendritic cells productively infected with immunodeficiency viruses transmit infection to T cells.
Medical microbiology and immunology 1995;184(3):129-34.
1995: C Krziwon; Ulrich Zähringer; K Kawahara; B Weidemann; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Glycosphingolipids from Sphingomonas paucimobilis induce monokine production in human mononuclear cells.
Infection and immunity 1995;63(8):2899-905.
1995: J Schletter; Helmut Brade; Lore Brade; C Krüger; Harald Loppnow; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Binding of lipopolysaccharide (LPS) to an 80-kilodalton membrane protein of human cells is mediated by soluble CD14 and LPS-binding protein.
Infection and immunity 1995;63(7):2576-80.
1995: C Swider; A Laba; A Moniewska; Johannes Gerdes; Hans-Dieter Flad; Andrzej Lange
Presence of mRNA for interferon-gamma (IFN-gamma) in blood mononuclear cells is associated with an active stage I sarcoidosis.
Clinical and experimental immunology 1995;100(3):401-5.
1995: Juliusz Pryjma; Marek Zembala; Jaroslaw Baran; Martin Ernst; Hans-Dieter Flad
Elimination of monocytes from cultures activated with recall antigens.
Immunology letters 1995;46(3):229-35.
1995: Kai-Michael Toellner; D Scheel-Toellner; R Sprenger; Michael Duchrow; L H Trümper; Martin Ernst; Hans-Dieter Flad; Johannes Gerdes
The human germinal centre cells, follicular dendritic cells and germinal centre T cells produce B cell-stimulating cytokines.
Cytokine 1995;7(4):344-54.
1995: T Mattern; C Reich; Michael Duchrow; Siegfried Ansorge; Artur J Ulmer; Hans-Dieter Flad
Antibody-induced modulation of CD26 surface expression.
Immunology 1995;84(4):595-600.
1995: JE Ehlert; Frank Petersen; M H Kubbutat; Johannes Gerdes; Hans-Dieter Flad; Ernst Brandt
Limited and defined truncation at the C terminus enhances receptor binding and degranulation activity of the neutrophil-activating peptide 2 (NAP-2). Comparison of native and recombinant NAP-2 variants.
The Journal of biological chemistry 1995;270(11):6338-44.
1995: Uwe Schönbeck; Ernst Brandt; Frank Petersen; Hans-Dieter Flad; Harald Loppnow
IL-8 specifically binds to endothelial but not to smooth muscle cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(5):2375-83.
1995: Harald Loppnow; Felix Stelter; Uwe Schönbeck; C Schlüter; Martin Ernst; Christine Schütt; Hans-Dieter Flad
Endotoxin activates human vascular smooth muscle cells despite lack of expression of CD14 mRNA or endogenous membrane CD14.
Infection and immunity 1995;63(3):1020-6.
1995: A Thanhäuser; Andreas Böhle; B Schneider; N Reiling; T Mattern; Martin Ernst; Hans-Dieter Flad; Artur J Ulmer
The induction of bacillus-Calmette-Guérin-activated killer cells requires the presence of monocytes and T-helper type-1 cells.
Cancer immunology, immunotherapy : CII 1995;40(2):103-8.
1995: Hans-Dieter Flad; J Gercken; L Hübner; C Schlüter; Juliusz Pryjma; Martin Ernst
Cytokines in mycobacterial infections: in vitro and ex vivo studies.
Archivum immunologiae et therapiae experimentalis 1995;43(2):153-8.
1995: Michael Duchrow; C Schlüter; G Key; M H Kubbutat; C Wohlenberg; Hans-Dieter Flad; Johannes Gerdes
Cell proliferation-associated nuclear antigen defined by antibody Ki-67: a new kind of cell cycle-maintaining proteins.
Archivum immunologiae et therapiae experimentalis 1995;43(2):117-21.
1995: Juliusz Pryjma; Marek Zembala; Martin Ernst; Hans-Dieter Flad
Preactivation and phenotype of monocytes have no influence on their elimination from culture by activated T lymphocytes.
Archivum immunologiae et therapiae experimentalis 1995;43(1):31-5.
1995: Elvira Richter; C Schlüter; Michael Duchrow; M Hahn; Sabine Rüsch-Gerdes; J Galle; Hans-Dieter Flad; Johannes Gerdes
An improved method for the species-specific assessment of mycobacteria in routinely formalin-fixed and paraffin-embedded tissues.
The Journal of pathology 1995;175(1):85-92.
1995: A Lange; A Moniewska; R Fetting; Martin Ernst; Hans-Dieter Flad
rIL-2-activated killer cell generation is influenced by autologous TNF-alpha production.
Natural immunity 1995;14(1):2-10.
1994: L Härter; Frank Petersen; Hans-Dieter Flad; Ernst Brandt
Connective tissue-activating peptide III desensitizes chemokine receptors on neutrophils. Requirement for proteolytic formation of the neutrophil-activating peptide 2.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(12):5698-708.
1994: B Weidemann; Helmut Brade; Ernst Th Rietschel; Roman Dziarski; V Bazil; S Kusumoto; Hans-Dieter Flad; Artur J Ulmer
Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures.
Infection and immunity 1994;62(11):4709-15.
1994: T Mattern; A Thanhäuser; N Reiling; Kai-Michael Toellner; Michael Duchrow; S Kusumoto; Ernst Th Rietschel; Martin Ernst; Helmut Brade; Hans-Dieter Flad
Endotoxin and lipid A stimulate proliferation of human T cells in the presence of autologous monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(7):2996-3004.
1994: Hans-Dieter Flad; E Richter; C Schlüter; Michael Duchrow; J Arnoldi; M Hahn; W Graf von Ballestrem; A E Alvarenga; Johannes Gerdes
Mycobacterium leprae DNA content, cellular and cytokine patterns in skin lesions of leprosy patients undergoing multidrug therapy (MDT).
Immunobiology 1994;191(4-5):388-94.
1994: E Richter; Michael Duchrow; C Schlüter; M Hahn; Hans-Dieter Flad; Johannes Gerdes
Detection of Mycobacterium leprae by three-primer PCR.
Immunobiology 1994;191(4-5):351-3.
1994: Frank Bühling; D Kunz; Dirk Reinhold; Artur J Ulmer; M Ernst; Hans-Dieter Flad; Siegfried Ansorge
Expression and functional role of dipeptidyl peptidase IV (CD26) on human natural killer cells.
Natural immunity 1994;13(5):270-9.
1994: A Werner; T Mattern; Artur J Ulmer; Hans-Dieter Flad; R Kurth; M Baier
CD26 is not required for infection of the lymphoma cell line C8166 with HIV-1.
AIDS (London, England) 1994;8(9):1348-9.
1994: J Gercken; Juliusz Pryjma; Martin Ernst; Hans-Dieter Flad
Defective antigen presentation by Mycobacterium tuberculosis-infected monocytes.
Infection and immunity 1994;62(8):3472-8.
1994: N Reiling; Artur J Ulmer; Michael Duchrow; Martin Ernst; Hans-Dieter Flad; Sunna Hauschildt
Nitric oxide synthase: mRNA expression of different isoforms in human monocytes/macrophages.
European journal of immunology 1994;24(8):1941-4.
1994: Dirk Reinhold; Ute Bank; Frank Bühling; Uwe Lendeckel; Artur J Ulmer; Hans-Dieter Flad; Siegfried Ansorge
Transforming growth factor-beta 1 (TGF-beta 1) inhibits DNA synthesis of PWM-stimulated PBMC via suppression of IL-2 and IL-6 production.
Cytokine 1994;6(4):382-8.
1994: S Kloth; Hans-Dieter Flad; Ernst Brandt
Detection of intracellular interleukin 2: evidence for novel immunologically related forms of the lymphokine.
Cytokine 1994;6(4):349-57.
1994: M H Kubbutat; G Key; Michael Duchrow; C Schlüter; Hans-Dieter Flad; Johannes Gerdes
Epitope analysis of antibodies recognising the cell proliferation associated nuclear antigen previously defined by the antibody Ki-67 (Ki-67 protein).
Journal of clinical pathology 1994;47(6):524-8.
1994: Juliusz Pryjma; Jaroslaw Baran; Martin Ernst; Maria Woloszyn; Hans-Dieter Flad
Altered antigen-presenting capacity of human monocytes after phagocytosis of bacteria.
Infection and immunity 1994;62(5):1961-7.
1994: I Dürrbaum-Landmann; E Kaltenhäuser; Hans-Dieter Flad; M Ernst
HIV-1 envelope protein gp120 affects phenotype and function of monocytes in vitro.
Journal of leukocyte biology 1994;55(4):545-51.
1994: Frank Petersen; Hans-Dieter Flad; Ernst Brandt
Neutrophil-activating peptides NAP-2 and IL-8 bind to the same sites on neutrophils but interact in different ways. Discrepancies in binding affinities, receptor densities, and biologic effects.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2467-78.
1994: B Schneider; A Thanhäuser; Dieter Jocham; H Loppnow; E Vollmer; J Galle; Hans-Dieter Flad; Artur J Ulmer; Andreas Böhle
Specific binding of bacillus Calmette-Guérin to urothelial tumor cells in vitro.
World journal of urology 1994;12(6):337-44.
1994: Andreas Böhle; A Thanhäuser; Artur J Ulmer; T Mattern; Martin Ernst; Hans-Dieter Flad; Dieter Jocham
On the mode of action of intravesical bacillus Calmette-Guérin: in vitro characterization of BCG-activated killer cells.
Urological research 1994;22(3):185-90.
1993: Andreas Böhle; A Thanhäuser; Artur J Ulmer; Martin Ernst; Hans-Dieter Flad; Dieter Jocham
Dissecting the immunobiological effects of Bacillus Calmette-Guérin (BCG) in vitro: evidence of a distinct BCG-activated killer (BAK) cell phenomenon.
The Journal of urology 1993;150(6):1932-7.
1993: E Grage-Griebenow; D Lorenzen; R Fetting; Hans-Dieter Flad; M Ernst
Phenotypical and functional characterization of Fc gamma receptor I (CD64)-negative monocytes, a minor human monocyte subpopulation with high accessory and antiviral activity.
European journal of immunology 1993;23(12):3126-35.
1993: C Schlüter; Michael Duchrow; C Wohlenberg; M H Becker; G Key; Hans-Dieter Flad; Johannes Gerdes
The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins.
The Journal of cell biology 1993;123(3):513-22.
1993: M H Wang; Y Q Chen; J Gercken; Martin Ernst; Andreas Böhle; Hans-Dieter Flad; Artur J Ulmer
Specific activation of human peripheral blood gamma/delta + lymphocytes by sonicated antigens of Mycobacterium tuberculosis: role in vitro in killing human bladder carcinoma cell lines.
Scandinavian journal of immunology 1993;38(3):239-46.
1993: A Thanhäuser; N Reiling; Andreas Böhle; Kai-Michael Toellner; Michael Duchrow; D Scheel; C Schlüter; Martin Ernst; Hans-Dieter Flad; Artur J Ulmer
Pentoxifylline: a potent inhibitor of IL-2 and IFN-gamma biosynthesis and BCG-induced cytotoxicity.
Immunology 1993;80(1):151-6.
1993: Dirk Reinhold; Ute Bank; Frank Bühling; Klaus Neubert; T Mattern; Artur J Ulmer; Hans-Dieter Flad; Siegfried Ansorge
Dipeptidyl peptidase IV (CD26) on human lymphocytes. Synthetic inhibitors of and antibodies against dipeptidyl peptidase IV suppress the proliferation of pokeweed mitogen-stimulated peripheral blood mononuclear cells, and IL-2 and IL-6 production.
Immunobiology 1993;188(4-5):403-14.
1993: Ernst Brandt; Frank Petersen; Hans-Dieter Flad
A novel molecular variant of the neutrophil-activating peptide NAP-2 with enhanced biological activity is truncated at the C-terminus: identification by antibodies with defined epitope specificity.
Molecular immunology 1993;30(11):979-91.
1993: A Thanhäuser; Andreas Böhle; Hans-Dieter Flad; Martin Ernst; T Mattern; Artur J Ulmer
Induction of bacillus-Calmette-Guérin-activated killer cells from human peripheral blood mononuclear cells against human bladder carcinoma cell lines in vitro.
Cancer immunology, immunotherapy : CII 1993;37(2):105-11.
1993: T Mattern; Siegfried Ansorge; Hans-Dieter Flad; Artur J Ulmer
Anti-CD26 monoclonal antibodies can reversibly arrest human T lymphocytes in the late G1 phase of the cell cycle.
Immunobiology 1993;188(1-2):36-50.
1993: G Key; M H Becker; B Baron; Michael Duchrow; C Schlüter; Hans-Dieter Flad; Johannes Gerdes
New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope.
Laboratory investigation; a journal of technical methods and pathology 1993;68(6):629-36.
1993: Ernst Th Rietschel; Lore Brade; F U Schade; Ulrich Seydel; Ulrich Zähringer; Uwe Mamat; G Schmidt; Artur J Ulmer; Harald Loppnow; Hans-Dieter Flad
[Bacterial endotoxins: relationship between chemical structure and biological effect].
Immunität und Infektion 1993;21(2):26-35.
1993: Hans-Dieter Flad; Harald Loppnow; Ernst Th Rietschel; Artur J Ulmer
Agonists and antagonists for lipopolysaccharide-induced cytokines.
Immunobiology 1993;187(3-5):303-16.
1993: M H Wang; Y Q Chen; Hans-Dieter Flad; H H Baer; W Feist; Artur J Ulmer
Inhibition of interleukin-6 release and T-cell proliferation by synthetic mirror pseudo cord factor analogues in human peripheral blood mononuclear cells.
FEMS immunology and medical microbiology 1993;6(1):53-61.
1992: Ernst Brandt; Frank Petersen; Hans-Dieter Flad
Recombinant tumor necrosis factor-alpha potentiates neutrophil degranulation in response to host defense cytokines neutrophil-activating peptide 2 and IL-8 by modulating intracellular cyclic AMP levels.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(4):1356-64.
1992: Artur J Ulmer; Holger Heine; W Feist; S Kusumoto; T Kusama; Helmut Brade; U Schade; Ernst Th Rietschel; Hans-Dieter Flad
Biological activity of synthetic phosphonooxyethyl analogs of lipid A and lipid A partial structures.
Infection and immunity 1992;60(8):3309-14.
1992: J Arnoldi; C Schlüter; Michael Duchrow; L Hübner; Martin Ernst; A Teske; Hans-Dieter Flad; Johannes Gerdes; E C Böttger
Species-specific assessment of Mycobacterium leprae in skin biopsies by in situ hybridization and polymerase chain reaction.
Laboratory investigation; a journal of technical methods and pathology 1992;66(5):618-23.
1992: Artur J Ulmer; T Mattern; Hans-Dieter Flad
Expression of CD26 (dipeptidyl peptidase IV) on memory and naive T lymphocytes.
Scandinavian journal of immunology 1992;35(5):551-9.
1992: M H Wang; Hans-Dieter Flad; W Feist; J Musehold; S Kusumoto; Helmut Brade; Johannes Gerdes; H T Rietschel; Artur J Ulmer
Inhibition of endotoxin or lipid A-induced tumor necrosis factor production by synthetic lipid A partial structures in human peripheral blood mononuclear cells.
Lymphokine and cytokine research 1992;11(1):23-31.
1992: Juliusz Pryjma; Bozenna Mytar; Harald Loppnow; Martin Ernst; Marek Zembala; Hans-Dieter Flad
FcR+ and FcR- monocytes differentially secrete monokines during pokeweed mitogen-induced T-cell-monocyte interactions.
Immunology 1992;75(2):355-60.
1992: Andreas Böhle; E Busemann; Johannes Gerdes; Artur J Ulmer; Hans-Dieter Flad; Dieter Jocham
Long-term immunobiological effects of intravesical bacillus Calmette-Guérin against bladder carcinoma recurrences.
Developments in biological standardization 1992;77():199-209.
1991: M H Wang; Hans-Dieter Flad; W Feist; Helmut Brade; S Kusumoto; Ernst Th Rietschel; Artur J Ulmer
Inhibition of endotoxin-induced interleukin-6 production by synthetic lipid A partial structures in human peripheral blood mononuclear cells.
Infection and immunity 1991;59(12):4655-64.
1991: Ernst Th Rietschel; Ulrich Seydel; Ulrich Zähringer; U F Schade; Lore Brade; Harald Loppnow; W Feist; M H Wang; Artur J Ulmer; Hans-Dieter Flad
Bacterial endotoxin: molecular relationships between structure and activity.
Infectious disease clinics of North America 1991;5(4):753-79.
1991: I Stahmer; J P Zimmer; M Ernst; T Fenner; R Finnern; H Schmitz; Hans-Dieter Flad; J Gerdes
Isolation of normal human follicular dendritic cells and CD4-independent in vitro infection by human immunodeficiency virus (HIV-1).
European journal of immunology 1991;21(8):1873-8.
1991: Juliusz Pryjma; Martin Ernst; R Fetting; Maria Woloszyn; Marek Zembala; Hans-Dieter Flad
The role of monocytes in the induction and regulation of IFN-gamma production by lectin-activated human T lymphocytes.
European cytokine network 1991;2(4):273-9.
1991: Ernst Brandt; J Van Damme; Hans-Dieter Flad
Neutrophils can generate their activator neutrophil-activating peptide 2 by proteolytic cleavage of platelet-derived connective tissue-activating peptide III.
Cytokine 1991;3(4):311-21.
1991: T Mattern; Wolfgang Scholz; A C Feller; Hans-Dieter Flad; Artur J Ulmer
Expression of CD26 (dipeptidyl peptidase IV) on resting and activated human T-lymphocytes.
Scandinavian journal of immunology 1991;33(6):737-48.
1991: Johannes Gerdes; L Li; C Schlueter; Michael Duchrow; C Wohlenberg; C Gerlach; I Stahmer; S Kloth; Ernst Brandt; Hans-Dieter Flad
Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67.
The American journal of pathology 1991;138(4):867-73.
1991: A Lange; R Fetting; B Jaźwiec; A Moniewska; J Ennen; Martin Ernst; Hans-Dieter Flad
Augmentation of interleukin 2-activated cytotoxicity after treatment of cells with inhibitors of interferon production.
Cellular immunology 1991;133(2):285-94.
1991: Frank Petersen; J Van Damme; Hans-Dieter Flad; Ernst Brandt
Neutrophil-activating polypeptides IL-8 and NAP-2 induce identical signal transduction pathways in the regulation of lysosomal enzyme release.
Lymphokine and cytokine research 1991;10(1-2):35-41.
1991: M H Wang; Hans-Dieter Flad; Andreas Böhle; Y Q Chen; Artur J Ulmer
Cellular cytotoxicity of human natural killer cells and lymphokine-activated killer cells against bladder carcinoma cell lines.
Immunology letters 1991;27(3):191-7.
1991: Hans-Dieter Flad; W Feist; M H Wang; Helmut Brade; Ernst Th Rietschel; Artur J Ulmer
Induction and modulation of interleukin 1 production by defined partial structures of lipopolysaccharide.
Behring Institute Mitteilungen 1991;(88):112-9.
1991: J Ennen; M Ernst; Hans-Dieter Flad
Activation of human monocytes by interleukin 2: role of T lymphocytes.
Journal of bioluminescence and chemiluminescence 1991;6(1):3-8.
1991: L Hübner; Martin Ernst; Dorothee von Laer; Stephan K Schwander; Hans-Dieter Flad
Enhancement of monocyte antimycobacterial activity by diethyldithiocarbamate (DTC).
International journal of immunopharmacology 1991;13(8):1067-72.
1990: M H Wang; W Feist; H Herzbeck; Helmut Brade; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad; Artur J Ulmer
Suppressive effect of lipid A partial structures on lipopolysaccharide or lipid A-induced release of interleukin 1 by human monocytes.
FEMS microbiology immunology 1990;2(3):179-85.
1990: J Arnoldi; Johannes Gerdes; Hans-Dieter Flad
Immunohistologic assessment of cytokine production of infiltrating cells in various forms of leprosy.
The American journal of pathology 1990;137(4):749-53.
1990: Hans-Dieter Flad; J Arnoldi; A Ohlert; J Kazda; Johannes Gerdes
Cytokine production and proliferative capacity of infiltrating cells in various forms of leprosy.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1990;41(3):307-9.
1990: C Kretschmer; D B Jones; K Morrison; C Schlüter; W Feist; Artur J Ulmer; J Arnoldi; J Matthes; T Diamantstein; Hans-Dieter Flad
Tumor necrosis factor alpha and lymphotoxin production in Hodgkin's disease.
The American journal of pathology 1990;137(2):341-51.
1990: Andreas Böhle; Johannes Gerdes; Artur J Ulmer; Alfons Hofstetter; Hans-Dieter Flad
Effects of local bacillus Calmette-Guerin therapy in patients with bladder carcinoma on immunocompetent cells of the bladder wall.
The Journal of urology 1990;144(1):53-8.
1990: Andreas Böhle; C Nowc; Artur J Ulmer; J Musehold; Johannes Gerdes; Alfons Hofstetter; Hans-Dieter Flad
Elevations of cytokines interleukin-1, interleukin-2 and tumor necrosis factor in the urine of patients after intravesical bacillus Calmette-Guerin immunotherapy.
The Journal of urology 1990;144(1):59-64.
1990: J Gerdes; C Kretschmer; G Zahn; M Ernst; D B Jones; Hans-Dieter Flad
Immunoenzymatic assessment of interferon-gamma in Hodgkin and Sternberg-Reed cells.
Cytokine 1990;2(4):307-10.
1990: Andreas Böhle; C Nowc; Artur J Ulmer; J Musehold; Johannes Gerdes; Alfons Hofstetter; Hans-Dieter Flad
Detection of urinary TNF, IL 1, and IL 2 after local BCG immunotherapy for bladder carcinoma.
Cytokine 1990;2(3):175-81.
1990: Artur J Ulmer; T Mattern; A C Feller; E Heymann; Hans-Dieter Flad
CD26 antigen is a surface dipeptidyl peptidase IV (DPPIV) as characterized by monoclonal antibodies clone TII-19-4-7 and 4EL1C7.
Scandinavian journal of immunology 1990;31(4):429-35.
1990: Artur J Ulmer; Juliusz Pryjma; Z Tarnok; Martin Ernst; Hans-Dieter Flad
Inhibitory and stimulatory effects of Pseudomonas aeruginosa pyocyanine on human T and B lymphocytes and human monocytes.
Infection and immunity 1990;58(3):808-15.
1990: Harald Loppnow; I Dürrbaum; Helmut Brade; C A Dinarello; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad
Lipid A, the immunostimulatory principle of lipopolysaccharides?
Advances in experimental medicine and biology 1990;256():561-6.
1990: Hans-Dieter Flad
Induction of IL-1 by lipopolysaccharide (LPS) and its modulation by synthetic lipid A precursor Ia.
Lymphokine research 1990;9(4):557-60.
1989: H Herzbeck; B Blum; W Rönspeck; B Frenzel; Ernst Brandt; Artur J Ulmer; Hans-Dieter Flad
Functional and molecular characterization of a monoclonal antibody against the 165-186 peptide of human IL-1 beta.
Scandinavian journal of immunology 1989;30(5):549-62.
1989: W Feist; Artur J Ulmer; J Musehold; Helmut Brade; S Kusumoto; Hans-Dieter Flad
Induction of tumor necrosis factor-alpha release by lipopolysaccharide and defined lipopolysaccharide partial structures.
Immunobiology 1989;179(4-5):293-307.
1989: Harald Loppnow; Hans-Dieter Flad; I Dürrbaum; J Musehold; R Fetting; Artur J Ulmer; H Herzbeck; Ernst Brandt
Detection of interleukin 1 with human dermal fibroblasts.
Immunobiology 1989;179(2-3):283-91.
1989: Harald Loppnow; Helmut Brade; I Dürrbaum; C A Dinarello; S Kusumoto; Ernst Th Rietschel; Hans-Dieter Flad
IL-1 induction-capacity of defined lipopolysaccharide partial structures.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(9):3229-38.
1989: J Ennen; Martin Ernst; Hans-Dieter Flad
The effect of interleukin 2 on Fc-gamma receptor function of human monocytes requires specific intercellular interaction.
Immunobiology 1989;179(1):17-32.
1989: Hans-Dieter Flad; Harald Loppnow; W Feist; M H Wang; Helmut Brade; S Kusumoto; Ernst Th Rietschel; Artur J Ulmer
Interleukin 1 and tumor necrosis factor: studies on the induction by lipopolysaccharide partial structures.
Lymphokine research 1989;8(3):235-8.
1989: Johannes Gerdes; H Herzbeck; C Schlüter; Hans-Dieter Flad
Immunoenzymatic assessment of IL-1 beta mRNA by in situ hybridization using sulphonated probes.
Lymphokine research 1989;8(3):239-43.
1989: Juliusz Pryjma; Hans-Dieter Flad; Bozenna Mytar; J Ennen; M Ernst
Effect of dexamethasone on mechanisms responsible for regulation of polyclonal B-cell response.
International journal of immunopharmacology 1989;11(8):871-7.
1989: Ernst Brandt; M Ernst; Harald Loppnow; Hans-Dieter Flad
Characterization of a platelet derived factor modulating phagocyte functions and cooperating with interleukin 1.
Lymphokine research 1989;8(3):281-7.
1989: Hans-Dieter Flad; H Kirchner; K Resch
Interleukin 1 and related cytokines.
Lymphokine research 1989;8(3):227-33.
1987: H J Horst; Hans-Dieter Flad
Corticosteroid-interleukin 2 interactions: inhibition of binding of interleukin 2 to interleukin 2 receptors.
Clinical and experimental immunology 1987;68(1):156-61.
1987: A Lange; Martin Ernst; B Jaźwiec; J Ennen; Hans-Dieter Flad
Large granular lymphocytes are central cells in the interleukin-2-dependent differentiation pathway of natural killer cells.
Natural immunity and cell growth regulation 1987;6(5):237-49.