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Hans-Dieter Flad

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
62
Ulmer, Artur
45
Ernst, Martin
34
Gerdes, Johannes
31
Brandt, Ernst
27
Rietschel, Ernst Th
21
Loppnow, Harald
21
Mattern, T
20
Petersen, Frank
18
Böhle, Andreas
17
Pryjma, Juliusz
16
Brade, Helmut
16
Duchrow, Michael
11
Grage-Griebenow, Evelin
10
Brade, Lore
9
Jocham, Dieter

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Publications

TOP 3
Schenk Birgit I; Petersen Frank; Flad Hans-Dieter; Brandt Ernst
Platelet-derived chemokines CXC chemokine ligand (CXCL)7, connective tissue-activating peptide III, and CXCL4 differentially affect and cross-regulate neutrophil adhesion and transendothelial migration.
Blumenthal Antje; Ehlers Stefan; Ernst Martin; Flad Hans-Dieter; Reiling Norbert
Control of mycobacterial replication in human macrophages: roles of extracellular signal-regulated kinases 1 and 2 and p38 mitogen-activated protein kinase pathways.
Bzowska Malgorzata; Guzik Krzysztof; Barczyk Katarzyna; Ernst Martin; Flad Hans-Dieter; Pryjma Juliusz
Increased IL-10 production during spontaneous apoptosis of monocytes.

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All Publications

2002: Schenk Birgit I; Petersen Frank; Flad Hans-Dieter; Brandt Ernst
Platelet-derived chemokines CXC chemokine ligand (CXCL)7, connective tissue-activating peptide III, and CXCL4 differentially affect and cross-regulate neutrophil adhesion and transendothelial migration.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(5):2602-10.
2002: Blumenthal Antje; Ehlers Stefan; Ernst Martin; Flad Hans-Dieter; Reiling Norbert
Control of mycobacterial replication in human macrophages: roles of extracellular signal-regulated kinases 1 and 2 and p38 mitogen-activated protein kinase pathways.
Infection and immunity 2002;70(9):4961-7.
2002: Bzowska Malgorzata; Guzik Krzysztof; Barczyk Katarzyna; Ernst Martin; Flad Hans-Dieter; Pryjma Juliusz
Increased IL-10 production during spontaneous apoptosis of monocytes.
European journal of immunology 2002;32(7):2011-20.
2002: Fleischer Jens; Grage-Griebenow Evelin; Kasper Brigitte; Heine Holger; Ernst Martin; Brandt Ernst; Flad Hans-Dieter; Petersen Frank
Platelet factor 4 inhibits proliferation and cytokine release of activated human T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(2):770-7.
2002: Schwartzkopff Franziska; Brandt Ernst; Petersen Frank; Flad Hans-Dieter; Bock Lothar; Ludwig Andreas
The CXC chemokine NAP-2 mediates differential heterologous desensitization of neutrophil effector functions elicited by platelet-activating factor.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2002;22(2):257-67.
2001: Seitzer U; Kayser K; Höhn H; Entzian P; Wacker H H; Ploetz S; Flad H D; Gerdes J; Maeurer M J
Reduced T-cell receptor CD3zeta-chain protein and sustained CD3epsilon expression at the site of mycobacterial infection.
Immunology 2001;104(3):269-77.
2001: Reiling N; Blumenthal A; Flad H D; Ernst M; Ehlers S
Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(6):3339-45.
2001: Muhvic D; El-Samalouti V; Flad H D; Radosevic-Stasic B; Rukavina D
The involvement of CD14 in the activation of human monocytes by peptidoglycan monomers.
Mediators of inflammation 2001;10(3):155-62.
2001: Baran J; Weglarczyk K; Mysiak M; Guzik K; Ernst M; Flad H D; Pryjma J
Fas (CD95)-Fas ligand interactions are responsible for monocyte apoptosis occurring as a result of phagocytosis and killing of Staphylococcus aureus.
Infection and immunity 2001;69(3):1287-97.
2001: Grage-Griebenow E; Flad H D; Ernst M
Heterogeneity of human peripheral blood monocyte subsets.
Journal of leukocyte biology 2001;69(1):11-20.
2001: Grage-Griebenow E; Zawatzky R; Kahlert H; Brade L; Flad H; Ernst M
Identification of a novel dendritic cell-like subset of CD64(+) / CD16(+) blood monocytes.
European journal of immunology 2001;31(1):48-56.
2001: Plötz S G; Lentschat A; Behrendt H; Plötz W; Hamann L; Ring J; Rietschel E T; Flad H D; Ulmer A J
The interaction of human peripheral blood eosinophils with bacterial lipopolysaccharide is CD14 dependent.
Blood 2001;97(1):235-41.
2000: Greinert U; Schlaak M; Rüsch-Gerdes S; Flad H D; Ernst M
Low in vitro production of interferon-gamma and tumor necrosis factor-alpha in HIV-seronegative patients with pulmonary disease caused by nontuberculous mycobacteria.
Journal of clinical immunology 2000;20(6):445-52.
2000: Ulmer A J; Flad H; Rietschel T; Mattern T
Induction of proliferation and cytokine production in human T lymphocytes by lipopolysaccharide (LPS).
Toxicology 2000;152(1-3):37-45.
2000: Ehlert J E; Ludwig A; Grimm T A; Lindner B; Flad H D; Brandt E
Down-regulation of neutrophil functions by the ELR(+) CXC chemokine platelet basic protein.
Blood 2000;96(9):2965-72.
2000: Brandt E; Ludwig A; Petersen F; Flad H D
Platelet-derived CXC chemokines: old players in new games.
Immunological reviews 2000;177():204-16.
2000: Petersen F; Spillmann D; Scheuerer B; Fleischer J; Flad H D; Brandt E
Is platelet factor-4 a chemokine?
European cytokine network 2000;11(3):506-7.
2000: Böhle A; Thanhäuser A; Ernst M; Flad H D; Rüsch-Gerdes S; Jocham D; Ulmer A J
Reduction of side effects of intravesical therapy with bacille Calmette-Guérin by pentoxifylline?--an in vitro approach.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;31 Suppl 3():S101-5.
2000: Brandau S; Böhle A; Thanhäuser A; Ernst M; Mattern T; Ulmer A J; Flad H D
In vitro generation of bacillus Calmette-Guérin-activated killer cells.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;31 Suppl 3():S94-S100.
2000: Brandau S; Suttmann H; Riemensberger J; Seitzer U; Arnold J; Durek C; Jocham D; Flad H D; Böhle A
Perforin-mediated lysis of tumor cells by Mycobacterium bovis Bacillus Calmette-Guérin-activated killer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3729-38.
2000: Brandau S; Suttmann H; Flad H D; Jocham D; Böhle A
Killing of Fas ligand-resistant renal carcioma cells by interleukin-2- and BCG-activated effector cells.
Cancer immunology, immunotherapy : CII 2000;49(7):369-76.
2000: Ludwig A; Ehlert J E; Flad H D; Brandt E
Identification of distinct surface-expressed and intracellular CXC-chemokine receptor 2 glycoforms in neutrophils: N-glycosylation is essential for maintenance of receptor surface expression.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(2):1044-52.
2000: Grage-Griebenow E; Flad H D; Ernst M; Bzowska M; Skrzeczyñska J; Pryjma J
Human MO subsets as defined by expression of CD64 and CD16 differ in phagocytic activity and generation of oxygen intermediates.
Immunobiology 2000;202(1):42-50.
2000: Brandt E; Petersen F; Ludwig A; Ehlert J E; Bock L; Flad H D
The beta-thromboglobulins and platelet factor 4: blood platelet-derived CXC chemokines with divergent roles in early neutrophil regulation.
Journal of leukocyte biology 2000;67(4):471-8.
2000: Scheuerer B; Ernst M; Dürrbaum-Landmann I; Fleischer J; Grage-Griebenow E; Brandt E; Flad H D; Petersen F
The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages.
Blood 2000;95(4):1158-66.
2000: Hamann L; Schumann R R; Flad H D; Brade L; Rietschel E T; Ulmer A J
Binding of lipopolysaccharide (LPS) to CHO cells does not correlate with LPS-induced NF-kappaB activation.
European journal of immunology 2000;30(1):211-6.
2000: el-Samalouti V T; Hamann L; Flad H D; Ulmer A J
The biology of endotoxin.
Methods in molecular biology (Clifton, N.J.) 2000;145():287-309.
1999: Petersen F; Bock L; Flad H D; Brandt E
Platelet factor 4-induced neutrophil-endothelial cell interaction: involvement of mechanisms and functional consequences different from those elicited by interleukin-8.
Blood 1999;94(12):4020-8.
1999: Durek C; Brandau S; Ulmer A J; Flad H D; Jocham D; Böhle A
Bacillus-Calmette-Guérin (BCG) and 3D tumors: an in vitro model for the study of adhesion and invasion.
The Journal of urology 1999;162(2):600-5.
1999: Swider C; Schnittger L; Bogunia-Kubik K; Gerdes J; Flad H; Lange A; Seitzer U
TNF-alpha and HLA-DR genotyping as potential prognostic markers in pulmonary sarcoidosis.
European cytokine network 1999;10(2):143-6.
1999: Lentschat A; El-Samalouti V T; Schletter J; Kusumoto S; Brade L; Rietschel E T; Gerdes J; Ernst M; Flad H; Ulmer A J
The internalization time course of a given lipopolysaccharide chemotype does not correspond to its activation kinetics in monocytes.
Infection and immunity 1999;67(5):2515-21.
1999: el-Samalouti V T; Schletter J; Chyla I; Lentschat A; Mamat U; Brade L; Flad H D; Ulmer A J; Hamann L
Identification of the 80-kDa LPS-binding protein (LMP80) as decay-accelerating factor (DAF, CD55).
FEMS immunology and medical microbiology 1999;23(3):259-69.
1999: Mattern T; Girroleit G; Flad H D; Rietschel E T; Ulmer A J
CD34(+) hematopoietic stem cells exert accessory function in lipopolysaccharide-induced T cell stimulation and CD80 expression on monocytes.
The Journal of experimental medicine 1999;189(4):693-700.
1999: Flad H D; Grage-Griebenow E; Petersen F; Scheuerer B; Brandt E; Baran J; Pryjma J; Ernst M
The role of cytokines in monocyte apoptosis.
Pathobiology : journal of immunopathology, molecular and cellular biology 1999;67(5-6):291-3.
1998: Grage-Griebenow E; Dürrbaum-Landmann I; Pryjma J; Loppnow H; Flad H D; Ernst M
Apoptosis in monocytes.
European cytokine network 1998;9(4):699-700.
1998: Loppnow H; Werdan K; Reuter G; Flad H D
The interleukin-1 and interleukin-1 converting enzyme families in the cardiovascular system.
European cytokine network 1998;9(4):675-80.
1998: Ehlert J E; Gerdes J; Flad H D; Brandt E
Novel C-terminally truncated isoforms of the CXC chemokine beta-thromboglobulin and their impact on neutrophil functions.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4975-82.
1998: Petersen F; Bock L; Flad H D; Brandt E
A chondroitin sulfate proteoglycan on human neutrophils specifically binds platelet factor 4 and is involved in cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):4347-55.
1998: Flad H D; Grage-Griebenow E; Scheuerer B; Dürrbaum-Landmann I; Petersen F; Brandt E; Fleischer J; Baran J; Pryjma J; Ernst M
The role of cytokines in monocyte apoptosis.
Research in immunology 1998;149(7-8):733-6.
1998: Hamann L; El-Samalouti V; Ulmer A J; Flad H D; Rietschel E T
Components of gut bacteria as immunomodulators.
International journal of food microbiology 1998;41(2):141-54.
1998: Seitzer U; Scheel-Toellner D; Mattern T; Haas H; Flad H D; Gerdes J
Staining pattern of seven monoclonal anti-CD26 antibodies in leprosy: implications for the use of CD26 as a surrogate marker of a human Th1-like reaction.
Virchows Archiv : an international journal of pathology 1998;432(4):343-7.
1998: Mattern T; Flad H D; Brade L; Rietschel E T; Ulmer A J
Stimulation of human T lymphocytes by LPS is MHC unrestricted, but strongly dependent on B7 interactions.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3412-8.
1998: Mattern T; Reich C; Schönbeck U; Ansorge S; Demuth H U; Loppnow H; Ulmer A J; Flad H D
CD26 (dipeptidyl peptidase i.v.) on human T lymphocytes does not mediate adhesion of these cells to endothelial cells or fibroblasts.
Immunobiology 1998;198(4):465-75.
1998: Loppnow H; Bil R; Hirt S; Schönbeck U; Herzberg M; Werdan K; Rietschel E T; Brandt E; Flad H D
Platelet-derived interleukin-1 induces cytokine production, but not proliferation of human vascular smooth muscle cells.
Blood 1998;91(1):134-41.
1998: Mattern T; Flad H D; Ulmer A J
Stimulation of human T lymphocytes by lipopolysaccaride (LPS) in the presence of autologous and heterologous monocytes.
Progress in clinical and biological research 1998;397():243-54.
1998: Hauschildt S; Ulmer A J; Flad H D; Heyden T; Heine H
ADP-ribosylation: role in LPS-induced phosphorylation of two cytosolic proteins (p36/38) in monocytes.
Progress in clinical and biological research 1998;397():147-55.
1998: Rietschel E T; Schletter J; Weidemann B; El-Samalouti V; Mattern T; Zähringer U; Seydel U; Brade H; Flad H D; Kusumoto S; Gupta D; Dziarski R; Ulmer A J
Lipopolysaccharide and peptidoglycan: CD14-dependent bacterial inducers of inflammation.
Microbial drug resistance (Larchmont, N.Y.) 1998;4(1):37-44.
1997: Hauschildt S; Schwarz C; Heine H; Ulmer A J; Flad H D; Rietschel E T; Jensen O N; Mann M
Actin: a target of lipopolysaccharide-induced phosphorylation in human monocytes.
Biochemical and biophysical research communications 1997;241(3):670-4.
1997: El-Samalouti V T; Schletter J; Brade H; Brade L; Kusumoto S; Rietschel E T; Flad H D; Ulmer A J
Detection of lipopolysaccharide (LPS)-binding membrane proteins by immuno-coprecipitation with LPS and anti-LPS antibodies.
European journal of biochemistry / FEBS 1997;250(2):418-24.
1997: Ludwig A; Petersen F; Zahn S; Götze O; Schröder J M; Flad H D; Brandt E
The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2.
Blood 1997;90(11):4588-97.
1997: Seitzer U; Swider C; Stüber F; Suchnicki K; Lange A; Richter E; Zabel P; Müller-Quernheim J; Flad H D; Gerdes J
Tumour necrosis factor alpha promoter gene polymorphism in sarcoidosis.
Cytokine 1997;9(10):787-90.
1997: Grage-Griebenow E; Baran J; Loppnow H; Los M; Ernst M; Flad H D; Pryjma J
An Fc gamma receptor I (CD64)-negative subpopulation of human peripheral blood monocytes is resistant to killing by antigen-activated CD4-positive cytotoxic T cells.
European journal of immunology 1997;27(9):2358-65.
1997: Schönbeck U; Mach F; Bonnefoy J Y; Loppnow H; Flad H D; Libby P
Ligation of CD40 activates interleukin 1beta-converting enzyme (caspase-1) activity in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1beta.
The Journal of biological chemistry 1997;272(31):19569-74.
1997: Seitzer U; Scheel-Toellner D; Toellner K M; Reiling N; Haas H; Galle J; Flad H D; Gerdes J
Properties of multinucleated giant cells in a new in vitro model for human granuloma formation.
The Journal of pathology 1997;182(1):99-105.
1997: Schönbeck U; Herzberg M; Petersen A; Wohlenberg C; Gerdes J; Flad H D; Loppnow H
Human vascular smooth muscle cells express interleukin-1beta-converting enzyme (ICE), but inhibit processing of the interleukin-1beta precursor by ICE.
The Journal of experimental medicine 1997;185(7):1287-94.
1997: Durek C; Schäfer I; Braasch H; Ulmer A J; Ernst M; Flad H D; Jocham D; Böhle A
Effects of colony-stimulating factors on cellular cytotoxicity.
Cancer immunology, immunotherapy : CII 1997;44(1):35-40.
1997: Weidemann B; Schletter J; Dziarski R; Kusumoto S; Stelter F; Rietschel E T; Flad H D; Ulmer A J
Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes.
Infection and immunity 1997;65(3):858-64.
1997: Flad H D; Härter L; Petersen F; Ehlert J E; Ludwig A; Bock L; Brandt E
Regulation of neutrophil activation by proteolytic processing of platelet-derived alpha-chemokines.
Advances in experimental medicine and biology 1997;421():223-30.
1997: Seitzer U; Scheel-Toellner D; Hahn M; Heinemann G; Mattern T; Flad H D; Gerdes J
Comparative study of CD26 as a Th1-like and CD30 as a potential Th2-like operational marker in leprosy.
Advances in experimental medicine and biology 1997;421():217-21.
1997: Hauschildt S; Scheipers P; Bessler W; Schwarz K; Ullmer A; Flad H D; Heine H
Role of ADP-ribosylation in activated monocytes/macrophages.
Advances in experimental medicine and biology 1997;419():249-52.
1996: Fleischer J; Soeth E; Reiling N; Grage-Griebenow E; Flad H D; Ernst M
Differential expression and function of CD80 (B7-1) and CD86 (B7-2) on human peripheral blood monocytes.
Immunology 1996;89(4):592-8.
1996: Holst O; Ulmer A J; Brade H; Flad H D; Rietschel E T
Biochemistry and cell biology of bacterial endotoxins.
FEMS immunology and medical microbiology 1996;16(2):83-104.
1996: Schromm A B; Brandenburg K; Rietschel E T; Flad H D; Carroll S F; Seydel U
Lipopolysaccharide-binding protein mediates CD14-independent intercalation of lipopolysaccharide into phospholipid membranes.
FEBS letters 1996;399(3):267-71.
1996: Dürrbaum-Landmann I; Gercken J; Flad H D; Ernst M
Effect of in vitro infection of human monocytes with low numbers of Mycobacterium tuberculosis bacteria on monocyte apoptosis.
Infection and immunity 1996;64(12):5384-9.
1996: Baran J; Guzik K; Hryniewicz W; Ernst M; Flad H D; Pryjma J
Apoptosis of monocytes and prolonged survival of granulocytes as a result of phagocytosis of bacteria.
Infection and immunity 1996;64(10):4242-8.
1996: Kröncke R; Loppnow H; Flad H D; Gerdes J
Human follicular dendritic cells and vascular cells produce interleukin-7: a potential role for interleukin-7 in the germinal center reaction.
European journal of immunology 1996;26(10):2541-4.
1996: Grage-Griebenow E; Flad H D; Ernst M
Fc gamma receptor I (CD64)-negative human monocytes are potent accessory cells in viral antigen-induced T cell activation and exhibit high IFN-alpha-producing capacity.
Journal of leukocyte biology 1996;60(3):389-96.
1996: Toellner K M; Scheel-Toellner D; Seitzer U; Sprenger R; Trümper L; Schlüter C; Flad H D; Gerdes J
The use of reverse transcription polymerase chain reaction to analyse large numbers of mRNA species from a single cell.
Journal of immunological methods 1996;191(1):71-5.
1996: Reiling N; Kröncke R; Ulmer A J; Gerdes J; Flad H D; Hauschildt S
Nitric oxide synthase: expression of the endothelial, Ca2+/calmodulin-dependent isoform in human B and T lymphocytes.
European journal of immunology 1996;26(3):511-6.
1996: Petersen F; Ludwig A; Flad H D; Brandt E
TNF-alpha renders human neutrophils responsive to platelet factor 4. Comparison of PF-4 and IL-8 reveals different activity profiles of the two chemokines.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(5):1954-62.
1996: Duchrow M; Schlüter C; Wohlenberg C; Flad H D; Gerdes J
Molecular characterization of the gene locus of the human cell proliferation-associated nuclear protein defined by monoclonal antibody Ki-67.
Cell proliferation 1996;29(1):1-12.
1996: Richter E; Greinert U; Kirsten D; Rüsch-Gerdes S; Schlüter C; Duchrow M; Galle J; Magnussen H; Schlaak M; Flad H D; Gerdes J
Assessment of mycobacterial DNA in cells and tissues of mycobacterial and sarcoid lesions.
American journal of respiratory and critical care medicine 1996;153(1):375-80.
1996: Rietschel E T; Brade H; Holst O; Brade L; Müller-Loennies S; Mamat U; Zähringer U; Beckmann F; Seydel U; Brandenburg K; Ulmer A J; Mattern T; Heine H; Schletter J; Loppnow H; Schönbeck U; Flad H D; Hauschildt S; Schade U F; Di Padova F; Kusumoto S; Schumann R R
Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification.
Current topics in microbiology and immunology 1996;216():39-81.
1995: Heine H; Ulmer A J; Flad H D; Hauschildt S
Lipopolysaccharide-induced change of phosphorylation of two cytosolic proteins in human monocytes is prevented by inhibitors of ADP-ribosylation.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):4899-908.
1995: Scheel-Toellner D; Richter E; Toellner K M; Reiling N; Wacker H H; Flad H D; Gerdes J
CD26 expression in leprosy and other granulomatous diseases correlates with the production of interferon-gamma.
Laboratory investigation; a journal of technical methods and pathology 1995;73(5):685-90.
1995: Sprenger R; Toellner K M; Schmetz C; Lüke W; Stahl-Hennig C; Ernst M; Hunsmann G; Schmitz H; Flad H D; Gerdes J
Follicular dendritic cells productively infected with immunodeficiency viruses transmit infection to T cells.
Medical microbiology and immunology 1995;184(3):129-34.
1995: Krziwon C; Zähringer U; Kawahara K; Weidemann B; Kusumoto S; Rietschel E T; Flad H D; Ulmer A J
Glycosphingolipids from Sphingomonas paucimobilis induce monokine production in human mononuclear cells.
Infection and immunity 1995;63(8):2899-905.
1995: Schletter J; Brade H; Brade L; Krüger C; Loppnow H; Kusumoto S; Rietschel E T; Flad H D; Ulmer A J
Binding of lipopolysaccharide (LPS) to an 80-kilodalton membrane protein of human cells is mediated by soluble CD14 and LPS-binding protein.
Infection and immunity 1995;63(7):2576-80.
1995: Swider C; Laba A; Moniewska A; Gerdes J; Flad H D; Lange A
Presence of mRNA for interferon-gamma (IFN-gamma) in blood mononuclear cells is associated with an active stage I sarcoidosis.
Clinical and experimental immunology 1995;100(3):401-5.
1995: Pryjma J; Zembala M; Baran J; Ernst M; Flad H D
Elimination of monocytes from cultures activated with recall antigens.
Immunology letters 1995;46(3):229-35.
1995: Toellner K M; Scheel-Toellner D; Sprenger R; Duchrow M; Trümper L H; Ernst M; Flad H D; Gerdes J
The human germinal centre cells, follicular dendritic cells and germinal centre T cells produce B cell-stimulating cytokines.
Cytokine 1995;7(4):344-54.
1995: Mattern T; Reich C; Duchrow M; Ansorge S; Ulmer A J; Flad H D
Antibody-induced modulation of CD26 surface expression.
Immunology 1995;84(4):595-600.
1995: Ehlert J E; Petersen F; Kubbutat M H; Gerdes J; Flad H D; Brandt E
Limited and defined truncation at the C terminus enhances receptor binding and degranulation activity of the neutrophil-activating peptide 2 (NAP-2). Comparison of native and recombinant NAP-2 variants.
The Journal of biological chemistry 1995;270(11):6338-44.
1995: Schönbeck U; Brandt E; Petersen F; Flad H D; Loppnow H
IL-8 specifically binds to endothelial but not to smooth muscle cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(5):2375-83.
1995: Loppnow H; Stelter F; Schönbeck U; Schlüter C; Ernst M; Schütt C; Flad H D
Endotoxin activates human vascular smooth muscle cells despite lack of expression of CD14 mRNA or endogenous membrane CD14.
Infection and immunity 1995;63(3):1020-6.
1995: Thanhäuser A; Böhle A; Schneider B; Reiling N; Mattern T; Ernst M; Flad H D; Ulmer A J
The induction of bacillus-Calmette-Guérin-activated killer cells requires the presence of monocytes and T-helper type-1 cells.
Cancer immunology, immunotherapy : CII 1995;40(2):103-8.
1995: Richter E; Schlüter C; Duchrow M; Hahn M; Rüsch-Gerdes S; Galle J; Flad H D; Gerdes J
An improved method for the species-specific assessment of mycobacteria in routinely formalin-fixed and paraffin-embedded tissues.
The Journal of pathology 1995;175(1):85-92.
1995: Lange A; Moniewska A; Fetting R; Ernst M; Flad H D
rIL-2-activated killer cell generation is influenced by autologous TNF-alpha production.
Natural immunity 1995;14(1):2-10.
1995: Flad H D; Gercken J; Hübner L; Schlüter C; Pryjma J; Ernst M
Cytokines in mycobacterial infections: in vitro and ex vivo studies.
Archivum immunologiae et therapiae experimentalis 1995;43(2):153-8.
1995: Duchrow M; Schlüter C; Key G; Kubbutat M H; Wohlenberg C; Flad H D; Gerdes J
Cell proliferation-associated nuclear antigen defined by antibody Ki-67: a new kind of cell cycle-maintaining proteins.
Archivum immunologiae et therapiae experimentalis 1995;43(2):117-21.
1995: Pryjma J; Zembala M; Ernst M; Flad H D
Preactivation and phenotype of monocytes have no influence on their elimination from culture by activated T lymphocytes.
Archivum immunologiae et therapiae experimentalis 1995;43(1):31-5.
1994: Härter L; Petersen F; Flad H D; Brandt E
Connective tissue-activating peptide III desensitizes chemokine receptors on neutrophils. Requirement for proteolytic formation of the neutrophil-activating peptide 2.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(12):5698-708.
1994: Weidemann B; Brade H; Rietschel E T; Dziarski R; Bazil V; Kusumoto S; Flad H D; Ulmer A J
Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures.
Infection and immunity 1994;62(11):4709-15.
1994: Mattern T; Thanhäuser A; Reiling N; Toellner K M; Duchrow M; Kusumoto S; Rietschel E T; Ernst M; Brade H; Flad H D
Endotoxin and lipid A stimulate proliferation of human T cells in the presence of autologous monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(7):2996-3004.
1994: Flad H D; Richter E; Schlüter C; Duchrow M; Arnoldi J; Hahn M; Graf von Ballestrem W; Alvarenga A E; Gerdes J
Mycobacterium leprae DNA content, cellular and cytokine patterns in skin lesions of leprosy patients undergoing multidrug therapy (MDT).
Immunobiology 1994;191(4-5):388-94.
1994: Richter E; Duchrow M; Schlüter C; Hahn M; Flad H D; Gerdes J
Detection of Mycobacterium leprae by three-primer PCR.
Immunobiology 1994;191(4-5):351-3.
1994: Bühling F; Kunz D; Reinhold D; Ulmer A J; Ernst M; Flad H D; Ansorge S
Expression and functional role of dipeptidyl peptidase IV (CD26) on human natural killer cells.
Natural immunity 1994;13(5):270-9.
1994: Werner A; Mattern T; Ulmer A J; Flad H D; Kurth R; Baier M
CD26 is not required for infection of the lymphoma cell line C8166 with HIV-1.
AIDS (London, England) 1994;8(9):1348-9.
1994: Gercken J; Pryjma J; Ernst M; Flad H D
Defective antigen presentation by Mycobacterium tuberculosis-infected monocytes.
Infection and immunity 1994;62(8):3472-8.
1994: Reiling N; Ulmer A J; Duchrow M; Ernst M; Flad H D; Hauschildt S
Nitric oxide synthase: mRNA expression of different isoforms in human monocytes/macrophages.
European journal of immunology 1994;24(8):1941-4.
1994: Reinhold D; Bank U; Bühling F; Lendeckel U; Ulmer A J; Flad H D; Ansorge S
Transforming growth factor-beta 1 (TGF-beta 1) inhibits DNA synthesis of PWM-stimulated PBMC via suppression of IL-2 and IL-6 production.
Cytokine 1994;6(4):382-8.
1994: Kloth S; Flad H D; Brandt E
Detection of intracellular interleukin 2: evidence for novel immunologically related forms of the lymphokine.
Cytokine 1994;6(4):349-57.
1994: Kubbutat M H; Key G; Duchrow M; Schlüter C; Flad H D; Gerdes J
Epitope analysis of antibodies recognising the cell proliferation associated nuclear antigen previously defined by the antibody Ki-67 (Ki-67 protein).
Journal of clinical pathology 1994;47(6):524-8.
1994: Pryjma J; Baran J; Ernst M; Woloszyn M; Flad H D
Altered antigen-presenting capacity of human monocytes after phagocytosis of bacteria.
Infection and immunity 1994;62(5):1961-7.
1994: Dürrbaum-Landmann I; Kaltenhäuser E; Flad H D; Ernst M
HIV-1 envelope protein gp120 affects phenotype and function of monocytes in vitro.
Journal of leukocyte biology 1994;55(4):545-51.
1994: Petersen F; Flad H D; Brandt E
Neutrophil-activating peptides NAP-2 and IL-8 bind to the same sites on neutrophils but interact in different ways. Discrepancies in binding affinities, receptor densities, and biologic effects.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2467-78.
1994: Schneider B; Thanhäuser A; Jocham D; Loppnow H; Vollmer E; Galle J; Flad H D; Ulmer A J; Böhle A
Specific binding of bacillus Calmette-Guérin to urothelial tumor cells in vitro.
World journal of urology 1994;12(6):337-44.
1994: Böhle A; Thanhäuser A; Ulmer A J; Mattern T; Ernst M; Flad H D; Jocham D
On the mode of action of intravesical bacillus Calmette-Guérin: in vitro characterization of BCG-activated killer cells.
Urological research 1994;22(3):185-90.
1993: Böhle A; Thanhäuser A; Ulmer A J; Ernst M; Flad H D; Jocham D
Dissecting the immunobiological effects of Bacillus Calmette-Guérin (BCG) in vitro: evidence of a distinct BCG-activated killer (BAK) cell phenomenon.
The Journal of urology 1993;150(6):1932-7.
1993: Grage-Griebenow E; Lorenzen D; Fetting R; Flad H D; Ernst M
Phenotypical and functional characterization of Fc gamma receptor I (CD64)-negative monocytes, a minor human monocyte subpopulation with high accessory and antiviral activity.
European journal of immunology 1993;23(12):3126-35.
1993: Schlüter C; Duchrow M; Wohlenberg C; Becker M H; Key G; Flad H D; Gerdes J
The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins.
The Journal of cell biology 1993;123(3):513-22.
1993: Wang M H; Chen Y Q; Gercken J; Ernst M; Böhle A; Flad H D; Ulmer A J
Specific activation of human peripheral blood gamma/delta + lymphocytes by sonicated antigens of Mycobacterium tuberculosis: role in vitro in killing human bladder carcinoma cell lines.
Scandinavian journal of immunology 1993;38(3):239-46.
1993: Thanhäuser A; Reiling N; Böhle A; Toellner K M; Duchrow M; Scheel D; Schlüter C; Ernst M; Flad H D; Ulmer A J
Pentoxifylline: a potent inhibitor of IL-2 and IFN-gamma biosynthesis and BCG-induced cytotoxicity.
Immunology 1993;80(1):151-6.
1993: Reinhold D; Bank U; Bühling F; Neubert K; Mattern T; Ulmer A J; Flad H D; Ansorge S
Dipeptidyl peptidase IV (CD26) on human lymphocytes. Synthetic inhibitors of and antibodies against dipeptidyl peptidase IV suppress the proliferation of pokeweed mitogen-stimulated peripheral blood mononuclear cells, and IL-2 and IL-6 production.
Immunobiology 1993;188(4-5):403-14.
1993: Brandt E; Petersen F; Flad H D
A novel molecular variant of the neutrophil-activating peptide NAP-2 with enhanced biological activity is truncated at the C-terminus: identification by antibodies with defined epitope specificity.
Molecular immunology 1993;30(11):979-91.
1993: Thanhäuser A; Böhle A; Flad H D; Ernst M; Mattern T; Ulmer A J
Induction of bacillus-Calmette-Guérin-activated killer cells from human peripheral blood mononuclear cells against human bladder carcinoma cell lines in vitro.
Cancer immunology, immunotherapy : CII 1993;37(2):105-11.
1993: Mattern T; Ansorge S; Flad H D; Ulmer A J
Anti-CD26 monoclonal antibodies can reversibly arrest human T lymphocytes in the late G1 phase of the cell cycle.
Immunobiology 1993;188(1-2):36-50.
1993: Key G; Becker M H; Baron B; Duchrow M; Schlüter C; Flad H D; Gerdes J
New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope.
Laboratory investigation; a journal of technical methods and pathology 1993;68(6):629-36.
1993: Rietschel E T; Brade L; Schade F U; Seydel U; Zähringer U; Mamat U; Schmidt G; Ulmer A J; Loppnow H; Flad H D
[Bacterial endotoxins: relationship between chemical structure and biological effect]
Immunität und Infektion 1993;21(2):26-35.
1993: Flad H D; Loppnow H; Rietschel E T; Ulmer A J
Agonists and antagonists for lipopolysaccharide-induced cytokines.
Immunobiology 1993;187(3-5):303-16.
1993: Wang M H; Chen Y Q; Flad H D; Baer H H; Feist W; Ulmer A J
Inhibition of interleukin-6 release and T-cell proliferation by synthetic mirror pseudo cord factor analogues in human peripheral blood mononuclear cells.
FEMS immunology and medical microbiology 1993;6(1):53-61.
1992: Ulmer A J; Heine H; Feist W; Kusumoto S; Kusama T; Brade H; Schade U; Rietschel E T; Flad H D
Biological activity of synthetic phosphonooxyethyl analogs of lipid A and lipid A partial structures.
Infection and immunity 1992;60(8):3309-14.
1992: Brandt E; Petersen F; Flad H D
Recombinant tumor necrosis factor-alpha potentiates neutrophil degranulation in response to host defense cytokines neutrophil-activating peptide 2 and IL-8 by modulating intracellular cyclic AMP levels.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(4):1356-64.
1992: Arnoldi J; Schlüter C; Duchrow M; Hübner L; Ernst M; Teske A; Flad H D; Gerdes J; Böttger E C
Species-specific assessment of Mycobacterium leprae in skin biopsies by in situ hybridization and polymerase chain reaction.
Laboratory investigation; a journal of technical methods and pathology 1992;66(5):618-23.
1992: Ulmer A J; Mattern T; Flad H D
Expression of CD26 (dipeptidyl peptidase IV) on memory and naive T lymphocytes.
Scandinavian journal of immunology 1992;35(5):551-9.
1992: Wang M H; Flad H D; Feist W; Musehold J; Kusumoto S; Brade H; Gerdes J; Rietschel H T; Ulmer A J
Inhibition of endotoxin or lipid A-induced tumor necrosis factor production by synthetic lipid A partial structures in human peripheral blood mononuclear cells.
Lymphokine and cytokine research 1992;11(1):23-31.
1992: Pryjma J; Mytar B; Loppnow H; Ernst M; Zembala M; Flad H D
FcR+ and FcR- monocytes differentially secrete monokines during pokeweed mitogen-induced T-cell-monocyte interactions.
Immunology 1992;75(2):355-60.
1992: Böhle A; Busemann E; Gerdes J; Ulmer A J; Flad H D; Jocham D
Long-term immunobiological effects of intravesical bacillus Calmette-Guérin against bladder carcinoma recurrences.
Developments in biological standardization 1992;77():199-209.
1991: Wang M H; Flad H D; Feist W; Brade H; Kusumoto S; Rietschel E T; Ulmer A J
Inhibition of endotoxin-induced interleukin-6 production by synthetic lipid A partial structures in human peripheral blood mononuclear cells.
Infection and immunity 1991;59(12):4655-64.
1991: Rietschel E T; Seydel U; Zähringer U; Schade U F; Brade L; Loppnow H; Feist W; Wang M H; Ulmer A J; Flad H D
Bacterial endotoxin: molecular relationships between structure and activity.
Infectious disease clinics of North America 1991;5(4):753-79.
1991: Stahmer I; Zimmer J P; Ernst M; Fenner T; Finnern R; Schmitz H; Flad H D; Gerdes J
Isolation of normal human follicular dendritic cells and CD4-independent in vitro infection by human immunodeficiency virus (HIV-1).
European journal of immunology 1991;21(8):1873-8.
1991: Pryjma J; Ernst M; Fetting R; Woloszyn M; Zembala M; Flad H D
The role of monocytes in the induction and regulation of IFN-gamma production by lectin-activated human T lymphocytes.
European cytokine network 1991;2(4):273-9.
1991: Brandt E; Van Damme J; Flad H D
Neutrophils can generate their activator neutrophil-activating peptide 2 by proteolytic cleavage of platelet-derived connective tissue-activating peptide III.
Cytokine 1991;3(4):311-21.
1991: Mattern T; Scholz W; Feller A C; Flad H D; Ulmer A J
Expression of CD26 (dipeptidyl peptidase IV) on resting and activated human T-lymphocytes.
Scandinavian journal of immunology 1991;33(6):737-48.
1991: Gerdes J; Li L; Schlueter C; Duchrow M; Wohlenberg C; Gerlach C; Stahmer I; Kloth S; Brandt E; Flad H D
Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67.
The American journal of pathology 1991;138(4):867-73.
1991: Lange A; Fetting R; Jazwiec B; Moniewska A; Ennen J; Ernst M; Flad H D
Augmentation of interleukin 2-activated cytotoxicity after treatment of cells with inhibitors of interferon production.
Cellular immunology 1991;133(2):285-94.
1991: Petersen F; Van Damme J; Flad H D; Brandt E
Neutrophil-activating polypeptides IL-8 and NAP-2 induce identical signal transduction pathways in the regulation of lysosomal enzyme release.
Lymphokine and cytokine research 1991;10(1-2):35-41.
1991: Wang M H; Flad H D; Böhle A; Chen Y Q; Ulmer A J
Cellular cytotoxicity of human natural killer cells and lymphokine-activated killer cells against bladder carcinoma cell lines.
Immunology letters 1991;27(3):191-7.
1991: Flad H D; Feist W; Wang M H; Brade H; Rietschel E T; Ulmer A J
Induction and modulation of interleukin 1 production by defined partial structures of lipopolysaccharide.
Behring Institute Mitteilungen 1991;(88):112-9.
1991: Ennen J; Ernst M; Flad H D
Activation of human monocytes by interleukin 2: role of T lymphocytes.
Journal of bioluminescence and chemiluminescence 1991;6(1):3-8.
1991: Hübner L; Ernst M; von Laer D; Schwander S; Flad H D
Enhancement of monocyte antimycobacterial activity by diethyldithiocarbamate (DTC).
International journal of immunopharmacology 1991;13(8):1067-72.
1990: Wang M H; Feist W; Herzbeck H; Brade H; Kusumoto S; Rietschel E T; Flad H D; Ulmer A J
Suppressive effect of lipid A partial structures on lipopolysaccharide or lipid A-induced release of interleukin 1 by human monocytes.
FEMS microbiology immunology 1990;2(3):179-85.
1990: Arnoldi J; Gerdes J; Flad H D
Immunohistologic assessment of cytokine production of infiltrating cells in various forms of leprosy.
The American journal of pathology 1990;137(4):749-53.
1990: Flad H D; Arnoldi J; Ohlert A; Kazda J; Gerdes J
Cytokine production and proliferative capacity of infiltrating cells in various forms of leprosy.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1990;41(3):307-9.
1990: Kretschmer C; Jones D B; Morrison K; Schlüter C; Feist W; Ulmer A J; Arnoldi J; Matthes J; Diamantstein T; Flad H D
Tumor necrosis factor alpha and lymphotoxin production in Hodgkin's disease.
The American journal of pathology 1990;137(2):341-51.
1990: Böhle A; Gerdes J; Ulmer A J; Hofstetter A G; Flad H D
Effects of local bacillus Calmette-Guerin therapy in patients with bladder carcinoma on immunocompetent cells of the bladder wall.
The Journal of urology 1990;144(1):53-8.
1990: Böhle A; Nowc C; Ulmer A J; Musehold J; Gerdes J; Hofstetter A G; Flad H D
Elevations of cytokines interleukin-1, interleukin-2 and tumor necrosis factor in the urine of patients after intravesical bacillus Calmette-Guerin immunotherapy.
The Journal of urology 1990;144(1):59-64.
1990: Gerdes J; Kretschmer C; Zahn G; Ernst M; Jones D B; Flad H D
Immunoenzymatic assessment of interferon-gamma in Hodgkin and Sternberg-Reed cells.
Cytokine 1990;2(4):307-10.
1990: Böhle A; Nowc C; Ulmer A J; Musehold J; Gerdes J; Hofstetter A G; Flad H D
Detection of urinary TNF, IL 1, and IL 2 after local BCG immunotherapy for bladder carcinoma.
Cytokine 1990;2(3):175-81.
1990: Ulmer A J; Mattern T; Feller A C; Heymann E; Flad H D
CD26 antigen is a surface dipeptidyl peptidase IV (DPPIV) as characterized by monoclonal antibodies clone TII-19-4-7 and 4EL1C7.
Scandinavian journal of immunology 1990;31(4):429-35.
1990: Ulmer A J; Pryjma J; Tarnok Z; Ernst M; Flad H D
Inhibitory and stimulatory effects of Pseudomonas aeruginosa pyocyanine on human T and B lymphocytes and human monocytes.
Infection and immunity 1990;58(3):808-15.
1990: Loppnow H; Dürrbaum I; Brade H; Dinarello C A; Kusumoto S; Rietschel E T; Flad H D
Lipid A, the immunostimulatory principle of lipopolysaccharides?
Advances in experimental medicine and biology 1990;256():561-6.
1990: Flad H D
Induction of IL-1 by lipopolysaccharide (LPS) and its modulation by synthetic lipid A precursor Ia.
Lymphokine research 1990;9(4):557-60.
1989: Herzbeck H; Blum B; Rönspeck W; Frenzel B; Brandt E; Ulmer A J; Flad H D
Functional and molecular characterization of a monoclonal antibody against the 165-186 peptide of human IL-1 beta.
Scandinavian journal of immunology 1989;30(5):549-62.
1989: Feist W; Ulmer A J; Musehold J; Brade H; Kusumoto S; Flad H D
Induction of tumor necrosis factor-alpha release by lipopolysaccharide and defined lipopolysaccharide partial structures.
Immunobiology 1989;179(4-5):293-307.
1989: Loppnow H; Flad H D; Dürrbaum I; Musehold J; Fetting R; Ulmer A J; Herzbeck H; Brandt E
Detection of interleukin 1 with human dermal fibroblasts.
Immunobiology 1989;179(2-3):283-91.
1989: Loppnow H; Brade H; Dürrbaum I; Dinarello C A; Kusumoto S; Rietschel E T; Flad H D
IL-1 induction-capacity of defined lipopolysaccharide partial structures.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(9):3229-38.
1989: Ennen J; Ernst M; Flad H D
The effect of interleukin 2 on Fc-gamma receptor function of human monocytes requires specific intercellular interaction.
Immunobiology 1989;179(1):17-32.
1989: Flad H D; Loppnow H; Feist W; Wang M H; Brade H; Kusumoto S; Rietschel E T; Ulmer A J
Interleukin 1 and tumor necrosis factor: studies on the induction by lipopolysaccharide partial structures.
Lymphokine research 1989;8(3):235-8.
1989: Gerdes J; Herzbeck H; Schlüter C; Flad H D
Immunoenzymatic assessment of IL-1 beta mRNA by in situ hybridization using sulphonated probes.
Lymphokine research 1989;8(3):239-43.
1989: Pryjma J; Flad H D; Mytar B; Ennen J; Ernst M
Effect of dexamethasone on mechanisms responsible for regulation of polyclonal B-cell response.
International journal of immunopharmacology 1989;11(8):871-7.
1989: Brandt E; Ernst M; Loppnow H; Flad H D
Characterization of a platelet derived factor modulating phagocyte functions and cooperating with interleukin 1.
Lymphokine research 1989;8(3):281-7.
1989: Flad H D; Kirchner H; Resch K
Interleukin 1 and related cytokines.
Lymphokine research 1989;8(3):227-33.
1987: Horst H J; Flad H D
Corticosteroid-interleukin 2 interactions: inhibition of binding of interleukin 2 to interleukin 2 receptors.
Clinical and experimental immunology 1987;68(1):156-61.
1987: Lange A; Ernst M; Jazwiec B; Ennen J; Flad H D
Large granular lymphocytes are central cells in the interleukin-2-dependent differentiation pathway of natural killer cells.
Natural immunity and cell growth regulation 1987;6(5):237-49.

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