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John Flanagan

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TOP 3
Diego Iglesias-Gato; Toshimasa Itoh; Lan Jiang; Atsushi Kittaka; Nathan K LeBrasseur; Gunnar Norstedt; Toshiyuki Sakaki; Keiko Yamamoto; Shasha Zheng; John N Flanagan; Tai C Chen
Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells.
Lisa Getty-Kaushik; Jason C Viereck; Jessie M Goodman; Zifang Guo; Nathan K LeBrasseur; Ann-Marie T Richard; John N Flanagan; Gordon C Yaney; James A Hamilton; Keith Tornheim
Mice deficient in phosphofructokinase-M have greatly decreased fat stores.
John N Flanagan; Shasha Zheng; Kun-Chun Chiang; Atsushi Kittaka; Toshiyuki Sakaki; Sachie Nakabayashi; Xiansi Zhao; Remco A Spanjaard; Kelly S Persons; Jeffrey S Mathieu; Michael F Holick; Tai C Chen
Evaluation of 19-nor-2alpha-(3-hydroxypropyl)-1alpha,25-dihydroxyvitamin D3 as a therapeutic agent for androgen-dependent prostate cancer.

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All Publications

2011: Diego Iglesias-Gato; Toshimasa Itoh; Lan Jiang; Atsushi Kittaka; Nathan K LeBrasseur; Gunnar Norstedt; Toshiyuki Sakaki; Keiko Yamamoto; Shasha Zheng; John N Flanagan; Tai C Chen
Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells.
The Journal of steroid biochemistry and molecular biology 2011;127(3-5):269-75.
2010: Lisa Getty-Kaushik; Jason C Viereck; Jessie M Goodman; Zifang Guo; Nathan K LeBrasseur; Ann-Marie T Richard; John N Flanagan; Gordon C Yaney; James A Hamilton; Keith Tornheim
Mice deficient in phosphofructokinase-M have greatly decreased fat stores.
Obesity (Silver Spring, Md.) 2010;18(3):434-40.
2009: John N Flanagan; Shasha Zheng; Kun-Chun Chiang; Atsushi Kittaka; Toshiyuki Sakaki; Sachie Nakabayashi; Xiansi Zhao; Remco A Spanjaard; Kelly S Persons; Jeffrey S Mathieu; Michael F Holick; Tai C Chen
Evaluation of 19-nor-2alpha-(3-hydroxypropyl)-1alpha,25-dihydroxyvitamin D3 as a therapeutic agent for androgen-dependent prostate cancer.
Anticancer research 2009;29(9):3547-53.
2008: Vandana Gupta; Shalender Bhasin; Wen Guo; Rajan Singh; Rika Miki; Pratibha Chauhan; Karen Choong; Tamara Tchkonia; Nathan K LeBrasseur; John N Flanagan; James A Hamilton; Jason C Viereck; Navjot S Narula; James L Kirkland; Ravi Jasuja
Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes.
Molecular and cellular endocrinology 2008;296(1-2):32-40.
2008: Lilin Wang; Kelly S Persons; Dan Jamieson; John N Flanagan; Hui H Hsu; Michael F Holick; Zhijun Luo; Toshi Sakaki; N Urushino; Douglas V Faller; Tai C Chen
Prostate 25-hydroxyvitamin D-1alpha-hydroxylase is up-regulated by suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor.
Anticancer research 2008;28(4A):2009-13.
2008: John N Flanagan; Pedro Pineda; Philip E Knapp; Antonio de las Morenas; Stephanie L Lee; Lewis E Braverman
Expression of cytokeratin 19 in the diagnosis of thyroid papillary carcinoma by quantitative polymerase chain reaction.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2008;14(2):168-74.
2007: Ann-Marie T Richard; Dominic-Luc Webb; Jessie M Goodman; Vera Schultz; John N Flanagan; Lisa Getty-Kaushik; Jude T Deeney; Gordon C Yaney; George A Dunaway; Per-Olof Berggren; Keith Tornheim
Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter: impairment in insulin secretion.
American journal of physiology. Endocrinology and metabolism 2007;293(3):E794-801.
2007: Monty Montano; John N Flanagan; Lan Jiang; Paola Sebastiani; Matthew Rarick; Nathan K LeBrasseur; Carl A Morris; Ravi Jasuja; Shalender Bhasin
Transcriptional profiling of testosterone-regulated genes in the skeletal muscle of human immunodeficiency virus-infected men experiencing weight loss.
The Journal of clinical endocrinology and metabolism 2007;92(7):2793-802.
2006: Michael Friedrich; Dagmar Diesing; Tim Cordes; Dorothea Fischer; Stefanie Becker; Tai C Chen; John N Flanagan; Vin Tangpricha; Ingrid Gherson; Michael F Holick; Jörg Reichrath
Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in normal and malignant breast tissue.
Anticancer research 2006;26(4A):2615-20.
2006: John N Flanagan; Michael V Young; Kelly S Persons; Lilin Wang; Jeffrey S Mathieu; Lyman W Whitlatch; Michael F Holick; Tai C Chen
Vitamin D metabolism in human prostate cells: implications for prostate cancer chemoprevention by vitamin D.
Anticancer research 2006;26(4A):2567-72.
2004: Michael V Young; Gary G Schwartz; Lilin Wang; Daniel P Jamieson; Lyman W Whitlatch; John N Flanagan; Bal Lokeshwar; Michael F Holick; Tai C Chen
The prostate 25-hydroxyvitamin D-1 alpha-hydroxylase is not influenced by parathyroid hormone and calcium: implications for prostate cancer chemoprevention by vitamin D.
Carcinogenesis 2004;25(6):967-71.
2004: Lilin Wang; John N Flanagan; Lyman W Whitlatch; Daniel P Jamieson; Michael F Holick; Tai C Chen
Regulation of 25-hydroxyvitamin D-1alpha-hydroxylase by epidermal growth factor in prostate cells.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):127-30.
2003: Tai C Chen; Lilin Wang; Lyman W Whitlatch; John N Flanagan; Michael F Holick
Prostatic 25-hydroxyvitamin D-1alpha-hydroxylase and its implication in prostate cancer.
Journal of cellular biochemistry 2003;88(2):315-22.
2003: Lilin Wang; Lyman W Whitlatch; John N Flanagan; Michael F Holick; Tai C Chen
Vitamin D autocrine system and prostate cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;164():223-37.
2003: John N Flanagan; Lilin Wang; Vin Tangpricha; Jörg Reichrath; Tai C Chen; Michael F Holick
Regulation of the 25-hydroxyvitamin D-1alpha-hydroxylase gene and its splice variant.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;164():157-67.
2002: Lyman W Whitlatch; Michael V Young; Gary G Schwartz; John N Flanagan; Kerry L Burnstein; Bal Lokeshwar; Edwin S Rich; Michael F Holick; Tai C Chen
25-Hydroxyvitamin D-1alpha-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer.
The Journal of steroid biochemistry and molecular biology 2002;81(2):135-40.
2001: John N Flanagan; Lyman W Whitlatch; Tai C Chen; X H Zhu; M T Holick; X F Kong; Michael F Holick
Enhancing 1 alpha-hydroxylase activity with the 25-hydroxyvitamin D-1 alpha-hydroxylase gene in cultured human keratinocytes and mouse skin.
The Journal of investigative dermatology 2001;116(6):910-4.
2001: Vin Tangpricha; John N Flanagan; Lyman W Whitlatch; C C Tseng; Tai C Chen; P R Holt; Martin Lipkin; Michael F Holick
25-hydroxyvitamin D-1alpha-hydroxylase in normal and malignant colon tissue.
Lancet 2001;357(9269):1673-4.