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Gert Jan Fleuren
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49
Kenter, Gemma
34
Cornelisse, Cees
32
Kuppen, Peter
26
van de Velde, Cornelis
25
Gorter, Arko
22
Eggermont, Alexander
22
Corver, Willem
21
Warnaar, SO
19
Melief, Cornelis
18
Trimbos, Baptist
17
van der Burg, Sjoerd
16
Litvinov, Sergey
16
Morreau, Hans
16
Offringa, Rienk
15
Bruijn, Jan
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All Publications
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2009: Kenter Gemma G; Welters Marij J P; Valentijn A Rob P M; Lowik Margriet J G; Berends-van der Meer Dorien M A; Vloon Annelies P G; Essahsah Farah; Fathers Lorraine M; Offringa Rienk; Drijfhout Jan Wouter; Wafelman Amon R; Oostendorp Jaap; Fleuren Gert Jan; van der Burg Sjoerd H; Melief Cornelis J M
Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia.
The New England journal of medicine 2009;361(19):1838-47.
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2008: de Vos van Steenwijk Peggy J; Piersma Sytse J; Welters Marij J P; van der Hulst Jeanette M; Fleuren Gertjan; Hellebrekers Bart W J; Kenter Gemma G; van der Burg Sjoerd H
Surgery followed by persistence of high-grade squamous intraepithelial lesions is associated with the induction of a dysfunctional HPV16-specific T-cell response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(22):7188-95.
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2008: Dierssen Jan Willem F; van Puijenbroek Marjo; Dezentjé David A; Fleuren Gert Jan; Cornelisse Cees J; van Wezel Tom; Offringa Rienk; Morreau Hans
Frequent mutations in the 3'-untranslated region of IFNGR1 lack functional impairment in microsatellite-unstable colorectal tumours.
European journal of human genetics : EJHG 2008;16(10):1235-9.
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2008: Vet J N I; de Boer M A; van den Akker B E W M; Siregar B; Lisnawati; Budiningsih S; Tyasmorowati D; Moestikaningsih; Cornain S; Peters A A W; Fleuren G J
Prevalence of human papillomavirus in Indonesia: a population-based study in three regions.
British journal of cancer 2008;99(1):214-8.
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2008: Kloth Judith N; Kenter Gemma G; Spijker H Siebe; Uljee Sandra; Corver Willem E; Jordanova Ekaterina S; Fleuren Gert Jan; Gorter Arko
Expression of Smad2 and Smad4 in cervical cancer: absent nuclear Smad4 expression correlates with poor survival.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21(7):866-75.
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2008: van den Hende Muriel; van Poelgeest Mariëtte I E; van der Hulst Jeanette M; de Jong Joan; Drijfhout Jan W; Fleuren Gert Jan; Valentijn A Rob P M; Wafelman Amon R; Slappendel Gijs M; Melief Cornelis J M; Offringa Rienk; van der Burg Sjoerd H; Kenter Gemma G
Skin reactions to human papillomavirus (HPV) 16 specific antigens intradermally injected in healthy subjects and patients with cervical neoplasia.
International journal of cancer. Journal international du cancer 2008;123(1):146-52.
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2008: Jordanova Ekaterina S; Gorter Arko; Ayachi Ouissam; Prins Frans; Durrant Lindy G; Kenter Gemma G; van der Burg Sjoerd H; Fleuren Gert Jan
Human leukocyte antigen class I, MHC class I chain-related molecule A, and CD8+/regulatory T-cell ratio: which variable determines survival of cervical cancer patients?
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(7):2028-35.
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2008: Piersma Sytse J; Welters Marij J P; van der Hulst Jeanette M; Kloth Judith N; Kwappenberg Kitty M C; Trimbos Baptist J; Melief Cornelis J M; Hellebrekers Bart W; Fleuren Gert Jan; Kenter Gemma G; Offringa Rienk; van der Burg Sjoerd H
Human papilloma virus specific T cells infiltrating cervical cancer and draining lymph nodes show remarkably frequent use of HLA-DQ and -DP as a restriction element.
International journal of cancer. Journal international du cancer 2008;122(3):486-94.
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2008: Welters Marij J P; Kenter Gemma G; Piersma Sytse J; Vloon Annelies P G; Löwik Margriet J G; Berends-van der Meer Dorien M A; Drijfhout Jan W; Valentijn A Rob P M; Wafelman Amon R; Oostendorp Jaap; Fleuren Gert Jan; Offringa Rienk; Melief Cornelis J M; van der Burg Sjoerd H
Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):178-87.
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2008: Kenter Gemma G; Welters Marij J P; Valentijn A Rob P M; Lowik Margriet J G; Berends-van der Meer Dorien M A; Vloon Annelies P G; Drijfhout Jan W; Wafelman Amon R; Oostendorp Jaap; Fleuren Gert Jan; Offringa Rienk; van der Burg Sjoerd H; Melief Cornelis J M
Phase I immunotherapeutic trial with long peptides spanning the E6 and E7 sequences of high-risk human papillomavirus 16 in end-stage cervical cancer patients shows low toxicity and robust immunogenicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):169-77.
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2008: Kloth Judith N; Gorter Arko; ter Haar Natalja; Corver Willem E; Jordanova Ekaterina S; Kenter Gemma G; Fleuren Gert Jan
Lack of TNFalpha mRNA expression in cervical cancer is not associated with loss of heterozygosity at 6p21.3, inactivating mutations or promoter methylation.
Molecular immunology 2008;45(1):152-9.
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2007: de Boer Marjon A; Jordanova Ekaterina S; van Poelgeest Mariëtte I E; van den Akker Brendy E; van der Burg Sjoerd H; Kenter Gemma G; Fleuren Gert Jan
Circulating human papillomavirus type 16 specific T-cells are associated with HLA Class I expression on tumor cells, but not related to the amount of viral oncogene transcripts.
International journal of cancer. Journal international du cancer 2007;121(12):2711-5.
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2007: Haven C J; van Puijenbroek M; Tan M H; Teh B T; Fleuren G J; van Wezel T; Morreau H
Identification of MEN1 and HRPT2 somatic mutations in paraffin-embedded (sporadic) parathyroid carcinomas.
Clinical endocrinology 2007;67(3):370-6.
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2007: van der Burg Sjoerd H; Piersma Sytse J; de Jong Annemieke; van der Hulst Jeanette M; Kwappenberg Kitty M C; van den Hende Muriel; Welters Marij J P; Van Rood Jon J; Fleuren Gert Jan; Melief Cornelis J M; Kenter Gemma G; Offringa Rienk
Association of cervical cancer with the presence of CD4+ regulatory T cells specific for human papillomavirus antigens.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):12087-92.
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2007: Hazelbag S; Kenter G G; Gorter A; Dreef E J; Koopman L A; Violette S M; Weinreb P H; Fleuren G J
Overexpression of the alpha v beta 6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival.
The Journal of pathology 2007;212(3):316-24.
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2007: Vermeulen Christine F W; Jordanova Ekaterina S; Szuhai Károly; Kolkman-Uljee Sandra; Vrede M Albert; Peters Alexander A W; Schuuring Ed; Fleuren Gert Jan
Physical status of multiple human papillomavirus genotypes in flow-sorted cervical cancer cells.
Cancer genetics and cytogenetics 2007;175(2):132-7.
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2007: Vermeulen Christine F W; Jordanova Ekaterina S; ter Haar Natalja T; Kolkman-Uljee Sandra M; de Miranda Noel F; Ferrone Soldano; Peters Alexander A W; Fleuren Gert Jan
Expression and genetic analysis of transporter associated with antigen processing in cervical carcinoma.
Gynecologic oncology 2007;105(3):593-9.
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2007: Mehta Akash M; Jordanova Ekaterina S; van Wezel Tom; Uh Hae-Won; Corver Willem E; Kwappenberg Kitty M C; Verduijn Willem; Kenter Gemma G; van der Burg Sjoerd H; Fleuren Gert J
Genetic variation of antigen processing machinery components and association with cervical carcinoma.
Genes, chromosomes & cancer 2007;46(6):577-86.
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2007: Vermeulen C F W; Boon M E; Grünberg A; van der Linden-Narain I B S; Vrede M A; Dekker F W; Peters A A W; Fleuren G J
Decreased prevalence of dysplasia in high-risk population immigrants in a low-risk area for cervical cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2007;17(3):646-50.
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2007: Tiersma E Stella M; Peters Alexander A W; van der Lee Marije L; Visser Adriaan P; Fleuren Gert Jan
Reasons for early interventions by gynaecologists in a clinical follow-up study on cervical intraepithelial neoplasia.
European journal of obstetrics, gynecology, and reproductive biology 2007;132(1):111-5.
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2007: Pieterse Q D; Kenter G G; Gaarenstroom K N; Peters A A W; Willems S M; Fleuren G J; Trimbos J B M Z
The number of pelvic lymph nodes in the quality control and prognosis of radical hysterectomy for the treatment of cervical cancer.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2007;33(2):216-21.
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2007: Zijlmans Henry J M A A; Fleuren Gert Jan; Baelde Hans J; Eilers Paul H C; Kenter Gemma G; Gorter Arko
Role of tumor-derived proinflammatory cytokines GM-CSF, TNF-alpha, and IL-12 in the migration and differentiation of antigen-presenting cells in cervical carcinoma.
Cancer 2007;109(3):556-65.
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2007: Piersma Sytse J; Jordanova Ekaterina S; van Poelgeest Mariëtte I E; Kwappenberg Kitty M C; van der Hulst Jeanette M; Drijfhout Jan W; Melief Cornelis J M; Kenter Gemma G; Fleuren Gert Jan; Offringa Rienk; van der Burg Sjoerd H
High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer.
Cancer research 2007;67(1):354-61.
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2007: de Boer Marjon A; Jordanova Ekaterina S; Kenter Gemma G; Peters Alexander A; Corver Willem E; Trimbos J Baptist; Fleuren Gert Jan
High human papillomavirus oncogene mRNA expression and not viral DNA load is associated with poor prognosis in cervical cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):132-8.
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2007: Dierssen Jan Willem F; de Miranda Noel F C C; Ferrone Soldano; van Puijenbroek Marjo; Cornelisse Cees J; Fleuren Gert Jan; van Wezel Tom; Morreau Hans
HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression.
BMC cancer 2007;7():33.
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2007: Kloth Judith N; Oosting Jan; van Wezel Tom; Szuhai Karoly; Knijnenburg Jeroen; Gorter Arko; Kenter Gemma G; Fleuren Gert Jan; Jordanova Ekaterina S
Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer.
BMC genomics 2007;8():53.
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2006: Sieben N L; Roemen G M J M; Oosting J; Fleuren G J; van Engeland M; Prat J
Clonal analysis favours a monoclonal origin for serous borderline tumours with peritoneal implants.
The Journal of pathology 2006;210(4):405-11.
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2006: Vermeulen Christine F W; Grünberg Antoon; Peters Lex A W; van der Linden-Narain Ingrid B S; Vrede M Albert; Krul Eveline J T; Dekker Friedo W; Fleuren Gert Jan
Ethnic patterns of cytologic abnormalities in cervical smears in suriname, a high-risk area for cervical cancer.
Acta cytologica 2006;50(6):621-6.
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2006: de Boer M A; Vet J N I; Aziz M F; Cornain S; Purwoto G; van den Akker B E W M; Dijkman A; Peters A A W; Fleuren G J
Human papillomavirus type 18 and other risk factors for cervical cancer in Jakarta, Indonesia.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2006;16(5):1809-14.
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2006: Sier Cornelis F M; Zuidwijk Kim; Zijlmans Henry J M A A; Hanemaaijer Roeland; Mulder-Stapel Adri A; Prins Frans A; Dreef Enno J; Kenter Gemma G; Fleuren Gert Jan; Gorter Arko
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2006;118(12):2991-8.
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2006: Zijlmans H J M A A; Fleuren G J; Baelde H J; Eilers P H C; Kenter G G; Gorter A
The absence of CCL2 expression in cervical carcinoma is associated with increased survival and loss of heterozygosity at 17q11.2.
The Journal of pathology 2006;208(4):507-17.
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2006: Welters Marij J P; van der Logt Pauline; van den Eeden Susan J F; Kwappenberg Kitty M C; Drijfhout Jan Wouter; Fleuren Gert Jan; Kenter Gemma G; Melief Cornelis J M; van der Burg Sjoerd H; Offringa Rienk
Detection of human papillomavirus type 18 E6 and E7-specific CD4+ T-helper 1 immunity in relation to health versus disease.
International journal of cancer. Journal international du cancer 2006;118(4):950-6.
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2006: van Poelgeest Mariëtte I E; Nijhuis Esther R; Kwappenberg Kitty M C; Hamming Ineke E; Wouter Drijfhout Jan; Fleuren Gert Jan; van der Zee Ate G J; Melief Cornelis J M; Kenter Gemma G; Nijman Hans W; Offringa Rienk; van der Burg Sjoerd H
Distinct regulation and impact of type 1 T-cell immunity against HPV16 L1, E2 and E6 antigens during HPV16-induced cervical infection and neoplasia.
International journal of cancer. Journal international du cancer 2006;118(3):675-83.
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2005: Vermeulen Christine F W; Jordanova Ekaterina S; Zomerdijk-Nooijen Yvon A; ter Haar Natalja T; Peters Alexander A W; Fleuren Gert Jan
Frequent HLA class I loss is an early event in cervical carcinogenesis.
Human immunology 2005;66(11):1167-73.
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2005: Sieben Nathalie L G; Oosting Jan; Flanagan Adrienne M; Prat Jaime; Roemen Guido M J M; Kolkman-Uljee Sandra M; van Eijk Ronald; Cornelisse Cees J; Fleuren Gert Jan; van Engeland Manon
Differential gene expression in ovarian tumors reveals Dusp 4 and Serpina 5 as key regulators for benign behavior of serous borderline tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(29):7257-64.
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2005: Kloth Judith N; Fleuren Gert Jan; Oosting Jan; de Menezes Renee X; Eilers Paul H C; Kenter Gemma G; Gorter Arko
Substantial changes in gene expression of Wnt, MAPK and TNFalpha pathways induced by TGF-beta1 in cervical cancer cell lines.
Carcinogenesis 2005;26(9):1493-502.
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2005: Tiersma E S M; van der Lee M L; Garssen B; Peters A A W; Visser A P; Fleuren G J; van Leeuwen K M; le Cessie S; Goodkin K
Psychosocial factors and the course of cervical intra-epithelial neoplasia: a prospective study.
Gynecologic oncology 2005;97(3):879-86.
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2005: Corver Willem E; Ter Haar Natalja T; Dreef Enno J; Miranda Noel F C C; Prins Frans A; Jordanova Ekaterina S; Cornelisse Cees J; Fleuren Gert Jan
High-resolution multi-parameter DNA flow cytometry enables detection of tumour and stromal cell subpopulations in paraffin-embedded tissues.
The Journal of pathology 2005;206(2):233-41.
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2005: De Boer Marjon A; Peters Lex A W; Aziz Mohammed Farid; Siregar Budiningsih; Cornain Santoso; Vrede M Albert; Jordanova Ekaterina S; Fleuren Gert Jan
Human papillomavirus type 18 variants: histopathology and E6/E7 polymorphisms in three countries.
International journal of cancer. Journal international du cancer 2005;114(3):422-5.
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2004: Hazelbag Suzanne; Kenter Gemma G; Gorter Arko; Fleuren Gert Jan
Prognostic relevance of TGF-beta1 and PAI-1 in cervical cancer.
International journal of cancer. Journal international du cancer 2004;112(6):1020-8.
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2004: Haven Carola J; Howell Viive M; Eilers Paul H C; Dunne Robert; Takahashi Masayuki; van Puijenbroek Marjo; Furge Kyle; Kievit Job; Tan Min-Han; Fleuren Gert Jan; Robinson Bruce G; Delbridge Leigh W; Philips Jeanette; Nelson Anne E; Krause Ulf; Dralle Henning; Hoang-Vu Cuong; Gimm Oliver; Morreau Hans; Marsh Deborah J; Teh Bin T
Gene expression of parathyroid tumors: molecular subclassification and identification of the potential malignant phenotype.
Cancer research 2004;64(20):7405-11.
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2004: Trimbos J B; Lambeek A F; Peters A A W; Wolterbeek R; Gaarenstroom K N; Fleuren G J; Kenter G G
Prognostic difference of surgical treatment of exophytic versus barrel-shaped bulky cervical cancer.
Gynecologic oncology 2004;95(1):77-81.
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2004: Ferber Matthew J; Eilers Paul; Schuuring Ed; Fenton James A L; Fleuren Gert Jan; Kenter Gemma; Szuhai Károly; Smith David I; Raap Anton K; Brink Antoinette A T P
Positioning of cervical carcinoma and Burkitt lymphoma translocation breakpoints with respect to the human papillomavirus integration cluster in FRA8C at 8q24.13.
Cancer genetics and cytogenetics 2004;154(1):1-9.
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2004: de Boer Marjon A; Peters Lex A W; Aziz Mohammed Farid; Siregar Budiningsih; Cornain Santoso; Vrede M Albert; Jordanova Ekaterina S; Kolkman-Uljee Sandra; Fleuren Gert Jan
Human papillomavirus type 16 E6, E7, and L1 variants in cervical cancer in Indonesia, Suriname, and The Netherlands.
Gynecologic oncology 2004;94(2):488-94.
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2004: de Jong Annemieke; van Poelgeest Mariëtte I E; van der Hulst Jeanette M; Drijfhout Jan Wouter; Fleuren Gert Jan; Melief Cornelis J M; Kenter Gemma; Offringa Rienk; van der Burg Sjoerd H
Human papillomavirus type 16-positive cervical cancer is associated with impaired CD4+ T-cell immunity against early antigens E2 and E6.
Cancer research 2004;64(15):5449-55.
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2004: Gelderman Kyra A; Kuppen Peter J K; Okada Noriko; Fleuren Gert Jan; Gorter Arko
Tumor-specific inhibition of membrane-bound complement regulatory protein Crry with bispecific monoclonal antibodies prevents tumor outgrowth in a rat colorectal cancer lung metastases model.
Cancer research 2004;64(12):4366-72.
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2004: Schellekens Maaike C; Dijkman Anneke; Aziz Mohammad Farid; Siregar Budiningsih; Cornain Santoso; Kolkman-Uljee Sandra; Peters Lex A W; Fleuren Gert Jan
Prevalence of single and multiple HPV types in cervical carcinomas in Jakarta, Indonesia.
Gynecologic oncology 2004;93(1):49-53.
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2004: Menon Anand G; Janssen-van Rhijn Connie M; Morreau Hans; Putter Hein; Tollenaar Rob A E M; van de Velde Cornelis J H; Fleuren Gert Jan; Kuppen Peter J K
Immune system and prognosis in colorectal cancer: a detailed immunohistochemical analysis.
Laboratory investigation; a journal of technical methods and pathology 2004;84(4):493-501.
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2004: Teh B T; Howell V M; Haven C J; Kahnoski K; Khoo S K; Petillo D; Chen J; Fleuren G J; Robinson B G; Delbridge L W; Philips J; Nelson A E; Krause U; Hammje K; Dralle H; Hoang-Vu C; Gimm O; Marsh D J; Morreau H
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):224.
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2004: Teh B T; Howell V M; Haven C J; Kahnoski K; Khoo S K; Petillo D; Chen J; Fleuren G J; Robinson B G; Delbridge L W; Philips J; Nelson A E; Krause U; Hammje K; Dralle H; Hoang-Vu C; Gimm O; Marsh D J; Morreau H
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):223.
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2004: Teh B T; Howell V M; Haven C J; Kahnoski K; Khoo S K; Petillo D; Chen J; Fleuren G J; Robinson B G; Delbridge L W; Philips J; Nelson A E; Krause U; Hammje K; Dralle H; Hoang-Vu C; Gimm O; Marsh D J; Morreau H
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):223.
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2004: Teh B T; Howell V M; Haven C J; Kahnoski K; Khoo S K; Petillo D; Chen J; Fleuren G J; Robinson B G; Delbridge L W; Philips J; Nelson A E; Krause U; Hammje K; Dralle H; Hoang-Vu C; Gimm O; Marsh D J; Morreau H
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):223.
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2004: Teh B T; Howell V M; Haven C J; Kahnoski K; Khoo S K; Petillo D; Chen J; Fleuren G J; Robinson B G; Delbridge L W; Philips J; Nelson A E; Krause U; Hammje K; Dralle H; Hoang-Vu C; Gimm O; Marsh D J; Morreau H
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):222.
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2004: Teh B T; Howell V M; Haven C J; Kahnoski K; Khoo S K; Petillo D; Chen J; Fleuren G J; Robinson B G; Delbridge L W; Philips J; Nelson A E; Krause U; Hammje K; Dralle H; Hoang-Vu C; Gimm O; Marsh D J; Morreau H
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):222.
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2004: Teh B T; Howell V M; Haven C J; Kahnoski K; Khoo S K; Petillo D; Chen J; Fleuren G J; Robinson B G; Delbridge L W; Philips J; Nelson A E; Krause U; Hammje K; Dralle H; Hoang-Vu C; Gimm O; Marsh D J; Morreau H
Human gene mutations. Gene symbol: HRPT2. Disease: Hyperparathyroidism Jaw-tumor syndrome.
Human genetics 2004;114(2):221.
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2004: Haven Carola J; van Puijenbroek Marjo; Karperien Marcel; Fleuren Gert-Jan; Morreau Hans
Differential expression of the calcium sensing receptor and combined loss of chromosomes 1q and 11q in parathyroid carcinoma.
The Journal of pathology 2004;202(1):86-94.
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2004: Menon Anand G; Tollenaar Rob A E M; van de Velde Cornelis J H; Putter Hein; Janssen-van Rhijn Connie M; Keijzer Rob; Fleuren Gert Jan; Kuppen Peter J K
p53 and HLA class-I expression are not down-regulated in colorectal cancer liver metastases.
Clinical & experimental metastasis 2004;21(1):79-85.
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2003: Howell V M; Haven C J; Kahnoski K; Khoo S K; Petillo D; Chen J; Fleuren G J; Robinson B G; Delbridge L W; Philips J; Nelson A E; Krause U; Hammje K; Dralle H; Hoang-Vu C; Gimm O; Marsh D J; Morreau H; Teh B T
HRPT2 mutations are associated with malignancy in sporadic parathyroid tumours.
Journal of medical genetics 2003;40(9):657-63.
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2003: Tiersma E S M; Peters A A W; Mooij H A; Fleuren G J
Visualising scanning patterns of pathologists in the grading of cervical intraepithelial neoplasia.
Journal of clinical pathology 2003;56(9):677-80.
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2003: Sieben Nathalie L G; Kolkman-Uljee Sandra M; Flanagan Adrienne M; le Cessie Saskia; Cleton-Jansen Anne-Marie; Cornelisse Cees J; Fleuren Gert Jan
Molecular genetic evidence for monoclonal origin of bilateral ovarian serous borderline tumors.
The American journal of pathology 2003;162(4):1095-101.
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2003: Menon Anand G; Fleuren Gert Jan; Alphenaar Ellen A; Jonges Liesbeth E; Janssen van Rhijn Connie M; Ensink N Geeske; Putter Hein; Tollenaar Rob A E M; van de Velde Cornelis J H; Kuppen Peter J K
A basal membrane-like structure surrounding tumour nodules may prevent intraepithelial leucocyte infiltration in colorectal cancer.
Cancer immunology, immunotherapy : CII 2003;52(2):121-6.
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2003: Welters Marij J P; de Jong Annemieke; van den Eeden Susan J F; van der Hulst Jeanette M; Kwappenberg Kitty M C; Hassane Sabrin; Franken Kees L M C; Drijfhout Jan Wouter; Fleuren Gert Jan; Kenter Gemma; Melief Cornelis J M; Offringa Rienk; van der Burg Sjoerd H
Frequent display of human papillomavirus type 16 E6-specific memory t-Helper cells in the healthy population as witness of previous viral encounter.
Cancer research 2003;63(3):636-41.
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2002: Hazelbag Suzanne; Gorter Arko; Kenter Gemma G; van den Broek Lambert; Fleuren Gertjan
Transforming growth factor-beta1 induces tumor stroma and reduces tumor infiltrate in cervical cancer.
Human pathology 2002;33(12):1193-9.
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2002: Menon Anand G; Morreau Hans; Tollenaar Rob A E M; Alphenaar E; Van Puijenbroek Marjo; Putter Hein; Janssen-Van Rhijn Connie M; Van De Velde Cornelis J H; Fleuren Gert Jan; Kuppen Peter J K
Down-regulation of HLA-A expression correlates with a better prognosis in colorectal cancer patients.
Laboratory investigation; a journal of technical methods and pathology 2002;82(12):1725-33.
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2002: Brink Antoinette A T P; Wiegant Joop C A G; Szuhai Károly; Tanke Hans J; Kenter Gemma G; Fleuren Gert-Jan; Schuuring Ed; Raap Anton K
Simultaneous mapping of human papillomavirus integration sites and molecular karyotyping in short-term cultures of cervical carcinomas by using 49-color combined binary ratio labeling fluorescence in situ hybridization.
Cancer genetics and cytogenetics 2002;134(2):145-50.
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2002: Gelderman Kyra A; Blok Vanessa T; Fleuren Gert Jan; Gorter Arko
The inhibitory effect of CD46, CD55, and CD59 on complement activation after immunotherapeutic treatment of cervical carcinoma cells with monoclonal antibodies or bispecific monoclonal antibodies.
Laboratory investigation; a journal of technical methods and pathology 2002;82(4):483-93.
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2002: Corver Willem E; Fleuren Gert Jan; Cornelisse Cees J
Software compensation improves the analysis of heterogeneous tumor samples stained for multiparameter DNA flow cytometry.
Journal of immunological methods 2002;260(1-2):97-107.
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2002: Gelderman Kyra A; Kuppen Peter J K; Bruin Wouter; Fleuren Gert Jan; Gorter Arko
Enhancement of the complement activating capacity of 17-1A mAb to overcome the effect of membrane-bound complement regulatory proteins on colorectal carcinoma.
European journal of immunology 2002;32(1):128-35.
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2001: Kuppen P J; Gorter A; Hagenaars M; Jonges L E; Giezeman-Smits K M; Nagelkerke J F; Fleuren G; van de Velde C J
Role of NK cells in adoptive immunotherapy of metastatic colorectal cancer in a syngeneic rat model.
Immunological reviews 2001;184():236-43.
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2001: Szuhai K; Sandhaus E; Kolkman-Uljee S M; Lemaître M; Truffert J C; Dirks R W; Tanke H J; Fleuren G J; Schuuring E; Raap A K
A novel strategy for human papillomavirus detection and genotyping with SybrGreen and molecular beacon polymerase chain reaction.
The American journal of pathology 2001;159(5):1651-60.
-
2001: Hazelbag S; Fleuren G J; Baelde J J; Schuuring E; Kenter G G; Gorter A
Cytokine profile of cervical cancer cells.
Gynecologic oncology 2001;83(2):235-43.
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2001: Jonges L E; Nagelkerke J F; Ensink N G; van der Velde E A; Tollenaar R A; Fleuren G J; van de Velde C J; Morreau H; Kuppen P J
Caspase-3 activity as a prognostic factor in colorectal carcinoma.
Laboratory investigation; a journal of technical methods and pathology 2001;81(5):681-8.
-
2001: Balzar M; Briaire-de Bruijn I H; Rees-Bakker H A; Prins F A; Helfrich W; de Leij L; Riethmüller G; Alberti S; Warnaar S O; Fleuren G J; Litvinov S V
Epidermal growth factor-like repeats mediate lateral and reciprocal interactions of Ep-CAM molecules in homophilic adhesions.
Molecular and cellular biology 2001;21(7):2570-80.
-
2001: van der Burg S H; Ressing M E; Kwappenberg K M; de Jong A; Straathof K; de Jong J; Geluk A; van Meijgaarden K E; Franken K L; Ottenhoff T H; Fleuren G J; Kenter G; Melief C J; Offringa R
Natural T-helper immunity against human papillomavirus type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: identification of 3 human leukocyte antigen class II-restricted epitopes.
International journal of cancer. Journal international du cancer 2001;91(5):612-8.
-
2001: Koelemij R; Hagenaars M; Ensink N G; Eggermont A M; Van De Velde C J; Fleuren G J; Kuppen P J
Administration of BiMAb-retargeted T cells in a rat hepatic metastases colon tumour model results in T-cell tumour infiltration independent of the route of administration.
Scandinavian journal of immunology 2001;53(3):277-81.
-
2001: Jonges L E; Albertsson P; van Vlierberghe R L; Ensink N G; Johansson B R; van de Velde C J; Fleuren G J; Nannmark U; Kuppen P J
The phenotypic heterogeneity of human natural killer cells: presence of at least 48 different subsets in the peripheral blood.
Scandinavian journal of immunology 2001;53(2):103-10.
-
2001: Kuppen P J; van der Eb M M; Jonges L E; Hagenaars M; Hokland M E; Nannmark U; Goldfarb R H; Basse P H; Fleuren G J; Hoeben R C; van de Velde C J
Tumor structure and extracellular matrix as a possible barrier for therapeutic approaches using immune cells or adenoviruses in colorectal cancer.
Histochemistry and cell biology 2001;115(1):67-72.
-
2000: Hellebrekers B W; Zwinderman A H; Kenter G G; Peters A A; Fleuren G J; Trimbos J B
[Surgical treatment of early stage cervical carcinoma at Leids University Medical Center, 1984-1996: depth of invasion, number and bilaterality of metastatic lymph nodes prognostic for recurrence]
Nederlands tijdschrift voor geneeskunde 2000;144(48):2304-9.
-
2000: Jonges L E; Giezeman-Smits K M; van Vlierberghe R L; Ensink N G; Hagenaars M; Joly E; Eggermont A M; van de Velde C J; Fleuren G J; Kuppen P J
NK cells modulate MHC class I expression on tumor cells and their susceptibility to lysis.
Immunobiology 2000;202(4):326-38.
-
2000: Sieben N L; ter Haar N T; Cornelisse C J; Fleuren G J; Cleton-Jansen A M
PCR artifacts in LOH and MSI analysis of microdissected tumor cells.
Human pathology 2000;31(11):1414-9.
-
2000: Corver W E; Koopman L A; Mulder A; Cornelisse C J; Fleuren G J
Distinction between HLA class I-positive and -negative cervical tumor subpopulations by multiparameter DNA flow cytometry.
Cytometry 2000;41(1):73-80.
-
2000: Kersemaekers A M; van de Vijver M J; Fleuren G J
Comparison of the genetic alterations in two epithelial collision tumors of the uterine cervix. A report of two cases.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2000;19(3):225-30.
-
2000: Bonsing B A; Corver W E; Fleuren G J; Cleton-Jansen A M; Devilee P; Cornelisse C J
Allelotype analysis of flow-sorted breast cancer cells demonstrates genetically related diploid and aneuploid subpopulations in primary tumors and lymph node metastases.
Genes, chromosomes & cancer 2000;28(2):173-83.
-
2000: Gaarenstroom K N; Kenter G G; Bonfrer J M; Korse C M; Van de Vijver M J; Fleuren G J; Trimbos J B
Can initial serum cyfra 21-1, SCC antigen, and TPA levels in squamous cell cervical cancer predict lymph node metastases or prognosis?
Gynecologic oncology 2000;77(1):164-70.
-
2000: Ressing M E; van Driel W J; Brandt R M; Kenter G G; de Jong J H; Bauknecht T; Fleuren G J; Hoogerhout P; Offringa R; Sette A; Celis E; Grey H; Trimbos B J; Kast W M; Melief C J
Detection of T helper responses, but not of human papillomavirus-specific cytotoxic T lymphocyte responses, after peptide vaccination of patients with cervical carcinoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(2):255-66.
-
2000: Koopman L A; Corver W E; van der Slik A R; Giphart M J; Fleuren G J
Multiple genetic alterations cause frequent and heterogeneous human histocompatibility leukocyte antigen class I loss in cervical cancer.
The Journal of experimental medicine 2000;191(6):961-76.
-
2000: Corver W E; Koopman L A; van der Aa J; Regensburg M; Fleuren G J; Cornelisse C J
Four-color multiparameter DNA flow cytometric method to study phenotypic intratumor heterogeneity in cervical cancer.
Cytometry 2000;39(2):96-107.
-
2000: Hagenaars M; Ensink N G; Eggermont A M; van der Velde E A; van de Velde C J; Fleuren G J; Kuppen P J
Endogenous natural killer cells do not play a role in antitumor effects induced by interleukin-2 in a syngeneic rat colon tumor model.
Cancer immunology, immunotherapy : CII 2000;48(10):561-8.
-
2000: Hagenaars M; Koelemij R; Ensink N G; van Eendenburg J D; van Vlierberghe R L; Eggermont A M; van de Velde C J; Fleuren G J; Kuppen P J
The development of novel mouse monoclonal antibodies against the CC531 rat colon adenocarcinoma.
Clinical & experimental metastasis 2000;18(4):281-9.
-
2000: Hagenaars M; Ensink N G; Basse P H; Hokland M; Nannmark U; Eggermont A M; van de Velde C J; Fleuren G J; Kuppen P J
The microscopic anatomy of experimental rat CC531 colon tumour metastases: consequences for immunotherapy?
Clinical & experimental metastasis 2000;18(2):189-96.
-
1999: Kersemaekers A M; van de Vijver M J; Kenter G G; Fleuren G J
Genetic alterations during the progression of squamous cell carcinomas of the uterine cervix.
Genes, chromosomes & cancer 1999;26(4):346-54.
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1999: Koelemij R; Kuppen P J; van de Velde C J; Fleuren G J; Hagenaars M; Eggermont A M
Bispecific antibodies in cancer therapy, from the laboratory to the clinic.
Journal of immunotherapy (Hagerstown, Md. : 1997) 1999;22(6):514-24.
-
1999: Koopman L A; Szuhai K; van Eendenburg J D; Bezrookove V; Kenter G G; Schuuring E; Tanke H; Fleuren G J
Recurrent integration of human papillomaviruses 16, 45, and 67 near translocation breakpoints in new cervical cancer cell lines.
Cancer research 1999;59(21):5615-24.
-
1999: Koopman L A; van Der Slik A R; Giphart M J; Fleuren G J
Human leukocyte antigen class I gene mutations in cervical cancer.
Journal of the National Cancer Institute 1999;91(19):1669-77.
-
1999: Krul E J; Kersemaekers A M; Zomerdijk-Nooyen Y A; Cornelisse C J; Peters L A; Fleuren G J
Different profiles of allelic losses in cervical carcinoma cases in Surinam and The Netherlands.
Cancer 1999;86(6):997-1004.
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1999: de Boer C J; van Dorst E; van Krieken H; Jansen-van Rhijn C M; Warnaar S O; Fleuren G J; Litvinov S V
Changing roles of cadherins and catenins during progression of squamous intraepithelial lesions in the uterine cervix.
The American journal of pathology 1999;155(2):505-15.
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1999: van Driel W J; Kievit-Tyson P; van den Broek L C; Zwinderman A H; Trimbos B J; Fleuren G J
Presence of an eosinophilic infiltrate in cervical squamous carcinoma results from a type 2 immune response.
Gynecologic oncology 1999;74(2):188-95.
-
1999: Giezeman-Smits K M; Gorter A; van Vlierberghe R L; v Eendenburg J D; Eggermont A M; Fleuren G J; Kuppen P J
The regulatory role of CD45 on rat NK cells in target cell lysis.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):71-6.
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1999: van Driel W J; Ressing M E; Kenter G G; Brandt R M; Krul E J; van Rossum A B; Schuuring E; Offringa R; Bauknecht T; Tamm-Hermelink A; van Dam P A; Fleuren G J; Kast W M; Melief C J; Trimbos J B
Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: clinical evaluation of a phase I-II trial.
European journal of cancer (Oxford, England : 1990) 1999;35(6):946-52.
-
1999: Krul E J; Schipper R F; Schreuder G M; Fleuren G J; Kenter G G; Melief C J
HLA and susceptibility to cervical neoplasia.
Human immunology 1999;60(4):337-42.
-
1999: Kersemaekers A M; Fleuren G J; Kenter G G; Van den Broek L J; Uljee S M; Hermans J; Van de Vijver M J
Oncogene alterations in carcinomas of the uterine cervix: overexpression of the epidermal growth factor receptor is associated with poor prognosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(3):577-86.
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1999: Hagenaars M; Ensink N G; Jonges L E; Chambers W H; Eggermont A M; van de Velde C J; Fleuren G J; Kuppen P J
The development of a bi-specific anti-CD161A x anti-tumor antibody for rat NK cell targeting.
Immunobiology 1999;200(1):31-48.
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1999: van Driel W J; Kenter G G; Fleuren G J; Melief C J; Trimbos B J
Immunotherapeutic strategies for cervical squamous carcinoma.
Hematology/oncology clinics of North America 1999;13(1):259-73.
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1999: Balzar M; Prins F A; Bakker H A; Fleuren G J; Warnaar S O; Litvinov S V
The structural analysis of adhesions mediated by Ep-CAM.
Experimental cell research 1999;246(1):108-21.
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1998: Hagenaars M; Zwaveling S; Kuppen P J; Ensink N G; Eggermont A M; Hokland M E; Basse P H; van de Velde C J; Fleuren G J; Nannmark U
Characteristics of tumor infiltration by adoptively transferred and endogenous natural-killer cells in a syngeneic rat model: implications for the mechanism behind anti-tumor responses.
International journal of cancer. Journal international du cancer 1998;78(6):783-9.
-
1998: van Dorst E B; van Muijen G N; Litvinov S V; Fleuren G J
The limited difference between keratin patterns of squamous cell carcinomas and adenocarcinomas is explicable by both cell lineage and state of differentiation of tumour cells.
Journal of clinical pathology 1998;51(9):679-84.
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1998: Velders M P; van Rhijn C M; Oskam E; Fleuren G J; Warnaar S O; Litvinov S V
The impact of antigen density and antibody affinity on antibody-dependent cellular cytotoxicity: relevance for immunotherapy of carcinomas.
British journal of cancer 1998;78(4):478-83.
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1998: Kersemaekers A M; Kenter G G; Hermans J; Fleuren G J; van de Vijver M J
Allelic loss and prognosis in carcinoma of the uterine cervix.
International journal of cancer. Journal international du cancer 1998;79(4):411-7.
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1998: Balzar M; Bakker H A; Briaire-de-Bruijn I H; Fleuren G J; Warnaar S O; Litvinov S V
Cytoplasmic tail regulates the intercellular adhesion function of the epithelial cell adhesion molecule.
Molecular and cellular biology 1998;18(8):4833-43.
-
1998: Koopman L A; Mulder A; Corver W E; Anholts J D; Giphart M J; Claas F H; Fleuren G J
HLA class I phenotype and genotype alterations in cervical carcinomas and derivative cell lines.
Tissue antigens 1998;51(6):623-36.
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1998: Blok V T; Daha M R; Tijsma O; Harris C L; Morgan B P; Fleuren G J; Gorter A
A bispecific monoclonal antibody directed against both the membrane-bound complement regulator CD55 and the renal tumor-associated antigen G250 enhances C3 deposition and tumor cell lysis by complement.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3437-43.
-
1998: Giezeman-Smits K M; Jonges L E; Chambers W H; Brisette-Storkus C S; Van Vlierberghe R L; Van Eendenburg J D; Eggermont A M; Fleuren G J; Kuppen P J
Novel monoclonal antibodies against membrane structures that are preferentially expressed on IL-2-activated rat NK cells.
Journal of leukocyte biology 1998;63(2):209-15.
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1998: Hagenaars M; Ensink N G; Koelemij R; Basse P H; Eggermont A M; van de Velde C J; Fleuren G J; Kuppen P J
Regional administration of natural killer cells in a rat hepatic metastasis model results in better tumor infiltration and anti-tumor response than systemic administration.
International journal of cancer. Journal international du cancer 1998;75(2):233-8.
-
1998: Kersemaekers A M; Hermans J; Fleuren G J; van de Vijver M J
Loss of heterozygosity for defined regions on chromosomes 3, 11 and 17 in carcinomas of the uterine cervix.
British journal of cancer 1998;77(2):192-200.
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1997: Abeln E C; Smit V T; Wessels J W; de Leeuw W J; Cornelisse C J; Fleuren G J
Molecular genetic evidence for the conversion hypothesis of the origin of malignant mixed müllerian tumours.
The Journal of pathology 1997;183(4):424-31.
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1997: Litvinov S V; Balzar M; Winter M J; Bakker H A; Briaire-de Bruijn I H; Prins F; Fleuren G J; Warnaar S O
Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins.
The Journal of cell biology 1997;139(5):1337-48.
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1997: Giezeman-Smits K M; Gorter A; Nagelkerke J F; van Vlierberghe R L; van Eendenburg J; Eggermont A M; Fleuren G J; Kuppen P J
Characterization of three new membrane structures on rat NK cells which are involved in activation of the lytic machinery.
Immunobiology 1997;197(5):429-43.
-
1997: Kagie M J; Kenter G G; Zomerdijk-Nooijen Y; Hermans J; Schuuring E; Timmers P J; Trimbos J B; Fleuren G J
Human papillomavirus infection in squamous cell carcinoma of the vulva, in various synchronous epithelial changes and in normal vulvar skin.
Gynecologic oncology 1997;67(2):178-83.
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1997: Kagie M J; Kenter G G; Tollenaar R A; Hermans J; Trimbos J B; Fleuren G J
p53 protein overexpression is common and independent of human papillomavirus infection in squamous cell carcinoma of the vulva.
Cancer 1997;80(7):1228-33.
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1997: Vierboom M P; Nijman H W; Offringa R; van der Voort E I; van Hall T; van den Broek L; Fleuren G J; Kenemans P; Kast W M; Melief C J
Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.
The Journal of experimental medicine 1997;186(5):695-704.
-
1997: Corver W E; Fleuren G J; Cornelisse C J
Improved single laser measurement of two cellular antigens and DNA-ploidy by the combined use of propidium iodide and TO-PRO-3 iodide.
Cytometry 1997;28(4):329-36.
-
1997: Bonsing B A; Corver W E; Gorsira M C; van Vliet M; Oud P S; Cornelisse C J; Fleuren G J
Specificity of seven monoclonal antibodies against p53 evaluated with Western blotting, immunohistochemistry, confocal laser scanning microscopy, and flow cytometry.
Cytometry 1997;28(1):11-24.
-
1997: Kagie M J; Kenter G G; Tollenaar R A; Hermans J; Trimbos J P; Fleuren G J
p53 protein overexpression, a frequent observation in squamous cell carcinoma of the vulva and in various synchronous vulvar epithelia, has no value as a prognostic parameter.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 1997;16(2):124-30.
-
1997: Tollenaar R A; Bonsing B A; Kuipers-Dijkshoorn N J; Hermans J; van de Velde C J; Cornelisse C J; Fleuren G J
Evidence of clonal divergence in colorectal carcinoma.
Cancer 1997;79(7):1304-14.
-
1997: Hazelbag H M; Van den Broek L J; Fleuren G J; Taminiau A H; Hogendoorn P C
Distribution of extracellular matrix components in adamantinoma of long bones suggests fibrous-to-epithelial transformation.
Human pathology 1997;28(2):183-8.
-
1997: Kagie M J; Kenter G G; Hermans J; Trimbos J B; Fleuren G J
The relevance of various vulvar epithelial changes in the early detection of squamous cell carcinoma of the vulva.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 1997;7(1):50-7.
-
1997: Luiten R M; Warnaar S O; Schuurman J; Pasmans S G; Latour S; Daëron M; Fleuren G J; Litvinov S V
Chimeric immunoglobulin E reactive with tumor-associated antigen activates human Fc epsilon RI bearing cells.
Human antibodies 1997;8(4):169-80.
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1996: van Bezooijen R L; Goey H; Stoter G; Hermans J; Fleuren G J
Prognostic markers for survival in patients with metastatic renal cell carcinoma treated with interleukin-2.
Cancer immunology, immunotherapy : CII 1996;43(5):293-8.
-
1996: van Driel W J; Ressing M E; Brandt R M; Toes R E; Fleuren G J; Trimbos J B; Kast W M; Melief C J
The current status of therapeutic HPV vaccine.
Annals of medicine 1996;28(6):471-7.
-
1996: Corver W E; Bonsing B A; Abeln E C; Vlak-Theil P M; Cornelisse C J; Fleuren G J
One-tube triple staining method for flow cytometric analysis of DNA ploidy and phenotypic heterogeneity of human solid tumors using single laser excitation.
Cytometry 1996;25(4):358-66.
-
1996: van Driel W J; Hogendoorn P C; Jansen F W; Zwinderman A H; Trimbos J B; Fleuren G J
Tumor-associated eosinophilic infiltrate of cervical cancer is indicative for a less effective immune response.
Human pathology 1996;27(9):904-11.
-
1996: Luiten R M; Coney L R; Fleuren G J; Warnaar S O; Litvinov S V
Generation of chimeric bispecific G250/anti-CD3 monoclonal antibody, a tool to combat renal cell carcinoma.
British journal of cancer 1996;74(5):735-44.
-
1996: Giezeman-Smits K M; Kuppen P J; Ensink N G; Eggermont A M; Stals F; Wonigeit K; Fleuren G J
The role of MHC class I expression in rat NK cell-mediated lysis of syngeneic tumor cells and virus-infected cells.
Immunobiology 1996;195(3):286-99.
-
1996: Velders M P; van Rhijn C M; Cornelissen I M; van Muijen G N; Briaire I H; Dohlsten M; Fleuren G J; Warnaar S O; Litvinov S V
The role of monoclonal antibody affinity in tumor immunotherapy evaluated in in vivo models for minimal residual disease.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1996;19(4):245-56.
-
1996: Schueler J A; Trimbos J B; vd Burg M; Cornelisse C J; Hermans J; Fleuren G J
DNA index reflects the biological behavior of ovarian carcinoma stage I-IIa.
Gynecologic oncology 1996;62(1):59-66.
-
1996: van Driel W J; Tjiong M Y; Hilders C G; Trimbos B J; Fleuren G J
Association of allele-specific HLA expression and histopathologic progression of cervical carcinoma.
Gynecologic oncology 1996;62(1):33-41.
-
1996: Gorter A; Blok V T; Haasnoot W H; Ensink N G; Daha M R; Fleuren G J
Expression of CD46, CD55, and CD59 on renal tumor cell lines and their role in preventing complement-mediated tumor cell lysis.
Laboratory investigation; a journal of technical methods and pathology 1996;74(6):1039-49.
-
1996: Kenter G G; Schoonderwald E M; Koelma I A; Arentz N; Hermans J; Fleuren G J
The cytological screening history of 469 patients with squamous cell carcinoma of the cervix uteri; does interval carcinoma exist?
Acta obstetricia et gynecologica Scandinavica 1996;75(4):400-3.
-
1996: Krul E J; Peters L A; Vandenbroucke J P; Vrede A; van Kanten R W; Fleuren G J
Cervical carcinoma in Surinam. Incidence and staging of cervical carcinoma between 1989 and 1994.
Cancer 1996;77(7):1329-33.
-
1996: Litvinov S V; van Driel W; van Rhijn C M; Bakker H A; van Krieken H; Fleuren G J; Warnaar S O
Expression of Ep-CAM in cervical squamous epithelia correlates with an increased proliferation and the disappearance of markers for terminal differentiation.
The American journal of pathology 1996;148(3):865-75.
-
1996: Luiten R M; Fleuren G J; Warnaar S O; Litvinov S V
Target-specific activation of mast cells by immunoglobulin E reactive with a renal cell carcinoma-associated antigen.
Laboratory investigation; a journal of technical methods and pathology 1996;74(2):467-75.
-
1996: Ressing M E; van Driel W J; Celis E; Sette A; Brandt M P; Hartman M; Anholts J D; Schreuder G M; ter Harmsel W B; Fleuren G J; Trimbos B J; Kast W M; Melief C J
Occasional memory cytotoxic T-cell responses of patients with human papillomavirus type 16-positive cervical lesions against a human leukocyte antigen-A *0201-restricted E7-encoded epitope.
Cancer research 1996;56(3):582-8.
-
1995: Hazelbag H M; Fleuren G J; Cornelisse C J; van den Broek L J; Taminiau A H; Hogendoorn P C
DNA aberrations in the epithelial cell component of adamantinoma of long bones.
The American journal of pathology 1995;147(6):1770-9.
-
1995: Abeln E C; Kuipers-Dijkshoorn N J; Berns E M; Henzen-Logmans S C; Fleuren G J; Cornelisse C J
Molecular genetic evidence for unifocal origin of advanced epithelial ovarian cancer and for minor clonal divergence.
British journal of cancer 1995;72(5):1330-6.
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1995: Velders M P; van Rhijn C M; Briaire I H; Fleuren G J; Warnaar S O; Litvinov S V
Immunotherapy with low and high affinity monoclonal antibodies 17-1A and 323/A3 in a nude mouse xenograft carcinoma model.
Cancer research 1995;55(19):4398-403.
-
1995: van Ravenswaay Claasen H H; Fleuren G J
The influence of combination chemotherapy on antigen expression in ovarian cancer.
Gynecologic oncology 1995;58(1):16-23.
-
1995: Hilders C G; Munoz I M; Nooyen Y; Fleuren G J
Altered HLA expression by metastatic cervical carcinoma cells as a factor in impaired immune surveillance.
Gynecologic oncology 1995;57(3):366-75.
-
1995: Fleuren G J; Gorter A; Kuppen P J; Litvinov S; Warnaar S O
Tumor heterogeneity and immunotherapy of cancer.
Immunological reviews 1995;145():91-122.
-
1995: Hazelbag H M; van den Broek L J; van Dorst E B; Offerhaus G J; Fleuren G J; Hogendoorn P C
Immunostaining of chain-specific keratins on formalin-fixed, paraffin-embedded tissues: a comparison of various antigen retrieval systems using microwave heating and proteolytic pre-treatments.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1995;43(4):429-37.
-
1995: Corver W E; Cornelisse C J; Hermans J; Fleuren G J
Limited loss of nine tumor-associated surface antigenic determinants after tryptic cell dissociation.
Cytometry 1995;19(3):267-72.
-
1994: Hazelbag H M; Taminiau A H; Fleuren G J; Hogendoorn P C
Adamantinoma of the long bones. A clinicopathological study of thirty-two patients with emphasis on histological subtype, precursor lesion, and biological behavior.
The Journal of bone and joint surgery. American volume 1994;76(10):1482-99.
-
1994: Devilee P; van Schothorst E M; Bardoel A F; Bonsing B; Kuipers-Dijkshoorn N; James M R; Fleuren G; van der Mey A G; Cornelisse C J
Allelotype of head and neck paragangliomas: allelic imbalance is confined to the long arm of chromosome 11, the site of the predisposing locus PGL.
Genes, chromosomes & cancer 1994;11(2):71-8.
-
1994: Abeln E C; Corver W E; Kuipers-Dijkshoorn N J; Fleuren G J; Cornelisse C J
Molecular genetic analysis of flow-sorted ovarian tumour cells: improved detection of loss of heterozygosity.
British journal of cancer 1994;70(2):255-62.
-
1994: van Velthuysen M L; Mayen A E; van Rooijen N; Fleuren G J; de Heer E; Bruijn J A
T cells and macrophages in Trypanosoma brucei-related glomerulopathy.
Infection and immunity 1994;62(8):3230-5.
-
1994: Hilders C G; Ras L; van Eendenburg J D; Nooyen Y; Fleuren G J
Isolation and characterization of tumor-infiltrating lymphocytes from cervical carcinoma.
International journal of cancer. Journal international du cancer 1994;57(6):805-13.
-
1994: Litvinov S V; Velders M P; Bakker H A; Fleuren G J; Warnaar S O
Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule.
The Journal of cell biology 1994;125(2):437-46.
-
1994: Velders M P; Litvinov S V; Warnaar S O; Gorter A; Fleuren G J; Zurawski V R; Coney L R
New chimeric anti-pancarcinoma monoclonal antibody with superior cytotoxicity-mediating potency.
Cancer research 1994;54(7):1753-9.
-
1994: van Duinen C M; van den Broek L J; Vermeer B J; Fleuren G J; Bruijn J A
The distribution of cellular adhesion molecules in pigmented skin lesions.
Cancer 1994;73(8):2131-9.
-
1994: Van den Broek L J; Hazelbag H M; Hilders C G; Fleuren G J
Antigen retrieval and microwaving.
European journal of morphology 1994;32(1):65-70.
-
1994: Corver W E; Cornelisse C J; Fleuren G J
Simultaneous measurement of two cellular antigens and DNA using fluorescein-isothiocyanate, R-phycoerythrin, and propidium iodide on a standard FACScan.
Cytometry 1994;15(2):117-28.
-
1994: Kuppen P J; Basse P H; Goldfarb R H; Van De Velde C J; Fleuren G J; Eggermont A M
The infiltration of experimentally induced lung metastases of colon carcinoma CC531 by adoptively transferred interleukin-2-activated natural killer cells in Wag rats.
International journal of cancer. Journal international du cancer 1994;56(4):574-9.
-
1994: van Dijk J; Uemura H; Beniers A J; Peelen W P; Zegveld S T; Fleuren G J; Warnaar S O; Oosterwijk E
Therapeutic effects of monoclonal antibody G250, interferons and tumor necrosis factor, in mice with renal-cell carcinoma xenografts.
International journal of cancer. Journal international du cancer 1994;56(2):262-8.
-
1994: Twaalfhoven F C; Fleuren G J; Cornelisse C J; Peters A A; Trimbos J B; Hogendoorn P C
Metastasis of breast carcinoma to a primary mucinous cystadenocarcinoma of the ovary.
Gynecologic oncology 1994;52(1):80-6.
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1994: Kuppen P J; Eggermont A M; Quak R B; Marinelli A; van de Velde C J; Fleuren G J
Soluble factors produced by macrophages/monocytes inhibit lymphokine-activated killer activity in rat splenocyte cultures.
Cancer immunology, immunotherapy : CII 1994;38(1):61-7.
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1994: Smits K M; Kuppen P J; Eggermont A M; Tamatani T; Miyasaka M; Fleuren G J
Rat interleukin-2-activated natural killer (A-NK) cell-mediated lysis is determined by the presence of CD18 on A-NK cells and the absence of major histocompatibility complex class I on target cells.
European journal of immunology 1994;24(1):171-5.
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1994: Van Duinen C M; Fleuren G J; Bruijn J A
The extracellular matrix in pigmented skin lesions: an immunohistochemical study.
Histopathology 1994;24(1):33-40.
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1994: Hilders C G; Houbiers J G; Krul E J; Fleuren G J
The expression of histocompatibility-related leukocyte antigens in the pathway to cervical carcinoma.
American journal of clinical pathology 1994;101(1):5-12.
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1994: van Velthuysen M L; Mayen A E; Prins F A; de Heer E; Bruijn J A; Fleuren G J
Phagocytosis by glomerular endothelial cells in infection-related glomerulopathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1994;9(8):1077-83.
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1993: Hilders C G; Houbiers J G; van Ravenswaay Claasen H H; Veldhuizen R W; Fleuren G J
Association between HLA-expression and infiltration of immune cells in cervical carcinoma.
Laboratory investigation; a journal of technical methods and pathology 1993;69(6):651-9.
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1993: Hazelbag H M; Fleuren G J; vd Broek L J; Taminiau A H; Hogendoorn P C
Adamantinoma of the long bones: keratin subclass immunoreactivity pattern with reference to its histogenesis.
The American journal of surgical pathology 1993;17(12):1225-33.
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1993: Smits K M; Kuppen P J; Eggermont A M; Fleuren G J
Preincubation of tumor cells with the anti-(MHC) class I antibody OX18 enhances tumor cell lysis by interleukin-2-activated NK cells.
Transplantation proceedings 1993;25(5):2806-7.
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1993: Smits K M; Kuppen P J; Lazeroms S P; Eggermont A M; Fleuren G J
Major histocompatibility complex class I expression and sensitivity to interleukin-2 activated NK cell-mediated lysis of adenovirus-transformed baby rat kidney cells.
Transplantation proceedings 1993;25(5):2804-5.
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1993: van Ravenswaay Claasen H H; van de Griend R J; Mezzanzanica D; Bolhuis R L; Warnaar S O; Fleuren G J
Analysis of production, purification, and cytolytic potential of bi-specific antibodies reactive with ovarian-carcinoma-associated antigens and the T-cell antigen CD3.
International journal of cancer. Journal international du cancer 1993;55(1):128-36.
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1993: Bonsing B A; Devilee P; Cleton-Jansen A M; Kuipers-Dijkshoorn N; Fleuren G J; Cornelisse C J
Evidence for limited molecular genetic heterogeneity as defined by allelotyping and clonal analysis in nine metastatic breast carcinomas.
Cancer research 1993;53(16):3804-11.
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1993: Beun G D; van de Velde C J; Fleuren G J; Eggermont A M
T-cell retargeting using bispecific monoclonal antibodies in a rat colon carcinoma model: IV. Tumor neutralization in Winn type assays.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(1):11-5.
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1993: Kuppen P J; Eggermont A M; Smits K M; van Eendenburg J D; Lazeroms S P; van de Velde C J; Fleuren G J
The development and purification of a bispecific antibody for lymphokine-activated killer cell targeting against the rat colon carcinoma CC531.
Cancer immunology, immunotherapy : CII 1993;36(6):403-8.
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1993: Gorter A; van de Griend R J; van Eendenburg J D; Haasnoot W H; Fleuren G J
Production of bi-specific monoclonal antibodies in a hollow-fibre bioreactor.
Journal of immunological methods 1993;161(2):145-50.
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1993: van Velthuysen M L; Veninga A; Bruijn J A; de Heer E; Fleuren G J
Susceptibility for infection-related glomerulopathy depends on non-MHC genes.
Kidney international 1993;43(3):623-9.
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1993: Beun G D; Gorter A; Nooyen Y; van de Velde C J; Fleuren G J
T cell retargeting using bispecific monoclonal antibodies in a rat colon carcinoma model. II. Syngeneic colon carcinoma CC531 is efficiently killed by retargeted cytotoxic T lymphocytes in vitro despite limited lysis in 51Cr release assays.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(6):2305-15.
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1993: Schueler J A; Cornelisse C J; Hermans J; Trimbos J B; van der Burg M E; Fleuren G J
Prognostic factors in well-differentiated early-stage epithelial ovarian cancer.
Cancer 1993;71(3):787-95.
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1993: Bonsing B A; Beerman H; Kuipers-Dijkshoorn N; Fleuren G J; Cornelisse C J
High levels of DNA index heterogeneity in advanced breast carcinomas. Evidence for DNA ploidy differences between lymphatic and hematogenous metastases.
Cancer 1993;71(2):382-91.
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1993: Kenter G G; Cornelisse C J; Jiwa N M; Aartsen E J; Hermans J; Mooi W; Heintz A P; Fleuren G J
Human papillomavirus type 16 in tumor tissue of low-stage squamous carcinoma of the uterine cervix in relation to ploidy grade and prognosis.
Cancer 1993;71(2):397-401.
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1993: Hogendoorn P C; van Dorst E B; van der Burg S H; Bruijn J A; Daha M R; Hoedemaeker P J; Fleuren G J
Antigen size influences the type of glomerular pathology in chronic serum sickness.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1993;8(8):703-10.
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1992: Kuppen P J; Marinelli A; Camps J A; Pauwels E K; van de Velde C J; Fleuren G J; Eggermont A M
Biodistribution of lymphokine-activated killer (LAK) cells in Wag rats after hepatic-artery or jugular-vein infusion.
International journal of cancer. Journal international du cancer 1992;52(2):266-70.
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1992: van Ravenswaay Claasen H H; Kluin P M; Fleuren G J
Tumor infiltrating cells in human cancer. On the possible role of CD16+ macrophages in antitumor cytotoxicity.
Laboratory investigation; a journal of technical methods and pathology 1992;67(2):166-74.
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1992: Beun G D; van Eendenburg D H; Corver W E; van de Velde C J; Fleuren G J
T-cell retargeting using bispecific monoclonal antibodies in a rat colon carcinoma model. I. Significant bispecific lysis of syngeneic colon carcinoma CC531 is critically dependent on prolonged preactivation of effector T-lymphocytes by immobilized anti-T-cell receptor antibody.
Journal of immunotherapy : official journal of the Society for Biological Therapy 1992;11(4):238-48.
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1992: Gorter A; Krüse K M; Schrier P I; Fleuren G J; van de Griend R J
Enhancement of the lytic activity of cloned human CD8 tumour-infiltrating lymphocytes by bispecific monoclonal antibodies.
Clinical and experimental immunology 1992;87(1):111-6.
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1992: Aten J; Stet R J; Wagenaar-Hilbers J P; Weening J J; Fleuren G J; Nieuwenhuis P
Glomerulopathy induced by graft-versus-host reaction in the rat. Requirement of donor CD4+ T lymphocytes and MHC class II incompatibility at the lymphoid compartment.
Scandinavian journal of immunology 1992;35(1):93-105.
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1992: van Velthuysen M L; Bruijn J A; van Leer E H; Fleuren G J
Pathogenesis of trypanosomiasis-induced glomerulonephritis in mice.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1992;7(6):507-15.
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1991: van Dijk J; Zegveld S T; Fleuren G J; Warnaar S O
Localization of monoclonal antibody G250 and bispecific monoclonal antibody CD3/G250 in human renal-cell carcinoma xenografts: relative effects of size and affinity.
International journal of cancer. Journal international du cancer 1991;48(5):738-43.
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1991: Twaalfhoven F C; Peters A A; Trimbos J B; Hermans J; Fleuren G J
The accuracy of frozen section diagnosis of ovarian tumors.
Gynecologic oncology 1991;41(3):189-92.
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1991: van der Mey A G; Cornelisse C J; Hermans J; Terpstra J L; Schmidt P H; Fleuren G J
DNA flow cytometry of hereditary and sporadic paragangliomas (glomus tumours).
British journal of cancer 1991;63(2):298-302.
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1991: Trimbos J B; Schueler J A; van der Burg M; Hermans J; van Lent M; Heintz A P; Fleuren G J
Watch and wait after careful surgical treatment and staging in well-differentiated early ovarian cancer.
Cancer 1991;67(3):597-602.
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1991: Offerhaus G J; Giardiello F M; Bruijn J A; Stijnen T; Molyvas E N; Fleuren G J
The value of immunohistochemistry for collagen IV expression in colorectal carcinomas.
Cancer 1991;67(1):99-105.
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1991: Hoedemaeker P J; Aten J; Hogendoorn P C; Kawasaki K; van Leer E H; de Heer E; Fleuren G J
Pathogenesis of glomerulonephritis: experimental models revisited.
Advances in nephrology from the Necker Hospital 1991;20():73-90.
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1991: Kuppen P J; Eggermont A M; Marinelli A; de Heer E; van de Velde C J; Fleuren G J
Induction of lymphokine-activated killer activity in rat splenocyte cultures: the importance of 2-mercaptoethanol and indomethacin.
Cancer immunology, immunotherapy : CII 1991;33(1):28-32.
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1990: Trimbos J B; Peters A A; Kenter G G; Nooy M A; Fleuren G J
[Lessons from gynecological-pathological discussions]
Nederlands tijdschrift voor geneeskunde 1990;134(49):2399-401.
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1990: Kenter G G; Cornelisse C J; Aartsen E J; Mooy W; Hermans J; Heintz A P; Fleuren G J
DNA ploidy level as prognostic factor in low stage carcinoma of the uterine cervix.
Gynecologic oncology 1990;39(2):181-5.
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1990: Smit V T; Fleuren G J; van Houwelingen J C; Zegveld S T; Kuipers-Dijkshoorn N J; Cornelisse C J
Flow cytometric DNA-ploidy analysis of synchronously occurring multiple malignant tumors of the female genital tract.
Cancer 1990;66(8):1843-9.
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1990: Bruijn J A; van Leer E H; Baelde H J; Corver W E; Hogendoorn P C; Fleuren G J
Characterization and in vivo transfer of nephritogenic autoantibodies directed against dipeptidyl peptidase IV and laminin in experimental lupus nephritis.
Laboratory investigation; a journal of technical methods and pathology 1990;63(3):350-9.
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1990: Trimbos J B; Schueler J A; van Lent M; Hermans J; Fleuren G J
Reasons for incomplete surgical staging in early ovarian carcinoma.
Gynecologic oncology 1990;37(3):374-7.
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1990: Bruijn J A; Hogendoorn P C; Corver W E; van den Broek L J; Hoedemaeker P J; Fleuren G J
Pathogenesis of experimental lupus nephritis: a role for anti-basement membrane and anti-tubular brush border antibodies in murine chronic graft-versus-host disease.
Clinical and experimental immunology 1990;79(1):115-22.
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1990: Hogendoorn P C; Bruijn J A; Gelok E W; Van den Broek L J; Fleuren G J
Development of progressive glomerulosclerosis in experimental chronic serum sickness.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1990;5(2):100-9.
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1989: Bruijn J A; Hoedemaeker P J; Fleuren G J
Pathogenesis of anti-basement membrane glomerulopathy and immune-complex glomerulonephritis: dichotomy dissolved.
Laboratory investigation; a journal of technical methods and pathology 1989;61(5):480-8.
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1989: Van Dijk J; Tsuruo T; Segal D M; Bolhuis R L; Colognola R; van de Griend R J; Fleuren G J; Warnaar S O
Bispecific antibodies reactive with the multidrug-resistance-related glycoprotein and CD3 induce lysis of multidrug-resistant tumor cells.
International journal of cancer. Journal international du cancer 1989;44(4):738-43.
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1989: Bruijn J A; Van Elven E H; Corver W E; Oudshoorn-Snoek M; Fleuren G J
Genetics of experimental lupus nephritis: non-H-2 factors determine susceptibility for renal involvement in murine chronic graft-versus-host disease.
Clinical and experimental immunology 1989;76(2):284-9.
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1989: van Dijk J; Warnaar S O; van Eendenburg J D; Thienpont M; Braakman E; Boot J H; Fleuren G J; Bolhuis R L
Induction of tumor-cell lysis by bi-specific monoclonal antibodies recognizing renal-cell carcinoma and CD3 antigen.
International journal of cancer. Journal international du cancer 1989;43(2):344-9.
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1988: Koelma I A; Nap M; van Steenis G J; Fleuren G J
Tumor markers for ovarian cancer. A comparative immunohistochemical and immunocytochemical study of two commercial monoclonal antibodies (OV632 and OC125).
American journal of clinical pathology 1988;90(4):391-6.
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1988: Smit V T; Cornelisse C J; De Jong D; Dijkshoorn N J; Peters A A; Fleuren G J
Analysis of tumor heterogeneity in a patient with synchronously occurring female genital tract malignancies by DNA flow cytometry, DNA fingerprinting, and immunohistochemistry.
Cancer 1988;62(6):1146-52.
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1988: Angeli S; Koelma I A; Fleuren G J; Van Steenis G J
Malignant melanoma in fine needle aspirates and effusions. An immunocytochemical study using monoclonal antibodies.
Acta cytologica 1988;32(5):707-12.
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1988: Smit V T; Boot A J; Smits A M; Fleuren G J; Cornelisse C J; Bos J L
KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas.
Nucleic acids research 1988;16(16):7773-82.
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1988: Fleuren G J; Nap M
Carcinoembryonic antigen in primary and metastatic ovarian tumors.
Gynecologic oncology 1988;30(3):407-15.
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1988: van Dijk J; Oosterwijk E; van Kroonenburgh M J; Jonas U; Fleuren G J; Pauwels E K; Warnaar S O
Perfusion of tumor-bearing kidneys as a model for scintigraphic screening of monoclonal antibodies.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1988;29(6):1078-82.
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1988: Bruijn J A; van Elven E H; Hogendoorn P C; Corver W E; Hoedemaeker P J; Fleuren G J
Murine chronic graft-versus-host disease as a model for lupus nephritis.
The American journal of pathology 1988;130(3):639-41.
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1988: Hogendoorn P C; Bruijn J A; vd Broek L J; De Heer E; Foidart J M; Hoedemaeker P J; Fleuren G J
Antibodies to purified renal tubular epithelial antigens contain activity against laminin, fibronectin, and type IV collagen.
Laboratory investigation; a journal of technical methods and pathology 1988;58(3):278-86.
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1988: Rodenburg C J; Cornelisse C J; Hermans J; Fleuren G J
DNA flow cytometry and morphometry as prognostic indicators in advanced ovarian cancer: a step forward in predicting the clinical outcome.
Gynecologic oncology 1988;29(2):176-87.
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1988: Rodenburg C J; Koelma I A; Nap M; Fleuren G J
Immunohistochemical detection of the ras oncogene product p21 in advanced ovarian cancer. Lack of correlation with clinical outcome.
Archives of pathology & laboratory medicine 1988;112(2):151-4.
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1988: Maes G; Fleuren G J; Bara J; Nap M
The distribution of mucins, carcinoembryonic antigen, and mucus-associated antigens in endocervical and endometrial adenocarcinomas.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 1988;7(2):112-22.
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1987: Fleuren G J; Nap M; Aalders J G; Trimbos J B; de Bruijn H W
Explanation of the limited correlation between tumor CA 125 content and serum CA 125 antigen levels in patients with ovarian tumors.
Cancer 1987;60(10):2437-42.
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1987: Bruijn J A; Oemar B S; Ehrich J H; Foidart J M; Fleuren G J
Anti-basement membrane glomerulopathy in experimental trypanosomiasis.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(7):2482-8.
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1987: Koelma I A; Nap M; Rodenburg C J; Fleuren G J
The value of tumour marker CA 125 in surgical pathology.
Histopathology 1987;11(3):287-94.
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1987: Bruijn J A; Smit V T; Que D G; Fleuren G J
Immunohistology of a sarcomatous mural nodule in an ovarian mucinous cystadenocarcinoma.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 1987;6(3):287-93.
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