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Dallas Flies

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TOP 3
Christopher M Jackson; Claudio A Mosse; Anil Parwani; Dallas B Flies; Edward L Hipkiss; Charles G Drake
Strain-specific induction of experimental autoimmune prostatitis (EAP) in mice.
Lieping Chen; Dallas B Flies
Molecular mechanisms of T cell co-stimulation and co-inhibition.
Dallas B Flies; Shengdian Wang; Haiying Xu; Lieping Chen
Cutting edge: A monoclonal antibody specific for the programmed death-1 homolog prevents graft-versus-host disease in mouse models.

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All Publications

2013: Christopher M Jackson; Claudio A Mosse; Anil Parwani; Dallas B Flies; Edward L Hipkiss; Charles G Drake
Strain-specific induction of experimental autoimmune prostatitis (EAP) in mice.
The Prostate 2013;73(6):651-6.
2013: Lieping Chen; Dallas B Flies
Molecular mechanisms of T cell co-stimulation and co-inhibition.
Nature reviews. Immunology 2013;13(4):227-42.
2011: Dallas B Flies; Shengdian Wang; Haiying Xu; Lieping Chen
Cutting edge: A monoclonal antibody specific for the programmed death-1 homolog prevents graft-versus-host disease in mouse models.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(4):1537-41.
2010: Loc T Nguyen; Bogoljub Ciric; Virginia P Van Keulen; Moses Rodriguez; Larry R Pease; Koji Tamada; Dallas B Flies; Lieping Chen
Retraction: Immunotherapeutic potential of B7-DC (PD-L2) cross-linking antibody in conferring antitumor immunity.
Cancer research 2010;70(22):9528.
2007: Yanhui Xu; Andrew S Flies; Dallas B Flies; Gefeng Zhu; Sudarshan Anand; Sarah J Flies; Haiying Xu; Robert A Anders; Wayne W Hancock; Lieping Chen; Koji Tamada
Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease.
Blood 2007;109(9):4097-104.
2007: Dallas B Flies; Lieping Chen
The new B7s: playing a pivotal role in tumor immunity.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(3):251-60.
2006: Sudarshan Anand; Pu Wang; Kiyoshi Yoshimura; In-Hak Choi; Anja Hilliard; Youhai H Chen; Chyung-Ru Wang; Richard D Schulick; Andrew S Flies; Dallas B Flies; Gefeng Zhu; Yanhui Xu; Drew M Pardoll; Lieping Chen; Koji Tamada
Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis.
The Journal of clinical investigation 2006;116(4):1045-51.
2006: Dallas B Flies; Lieping Chen
Modulation of immune response by B7 family molecules in tumor microenvironments.
Immunological investigations 2006;35(3-4):395-418.
2005: Charles G Drake; Amy D H Doody; Marianne A Mihalyo; Ching-Tai Huang; Erin Kelleher; TANNA RAVI; Edward L Hipkiss; Dallas B Flies; Eugene P Kennedy; Meixiao Long; Patrick W McGary; Lee Coryell; William G Nelson; Drew M Pardoll; Adam J. Adler
Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen.
Cancer cell 2005;7(3):239-49.
2005: Fumiya Hirano; Katsumi Kaneko; Hideto Tamura; Haidong Dong; Shengdian Wang; Masao Ichikawa; Cecilia Rietz; Dallas B Flies; Julie S Lau; Gefeng Zhu; Koji Tamada; Lieping Chen
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity.
Cancer research 2005;65(3):1089-96.
2004: Liqun Luo; Andrei I Chapoval; Dallas B Flies; Gefeng Zhu; Fumiya Hirano; Shengdian Wang; Julie S Lau; Haidong Dong; Koji Tamada; Andrew S Flies; Yang Liu; Lieping Chen
B7-H3 enhances tumor immunity in vivo by costimulating rapid clonal expansion of antigen-specific CD8+ cytolytic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5445-50.
2004: Ching-Tai Huang; Creg J Workman; Dallas B Flies; Xiaoyu Pan; Aimee L Marson; Gang Zhou; Edward L Hipkiss; TANNA RAVI; Jeanne Kowalski; Hyam I Levitsky; Jonathan D Powell; Drew M Pardoll; Charles G Drake; Dario A A Vignali
Role of LAG-3 in regulatory T cells.
Immunity 2004;21(4):503-13.
2004: Suresh Radhakrishnan; Loc Tan Nguyen; Bogoljub Ciric; Dallas B Flies; Virginia Van Keulen; Koji Tamada; Lieping Chen; Moses Rodriguez; Larry R Pease
Immunotherapeutic potential of B7-DC (PD-L2) cross-linking antibody in conferring antitumor immunity.
Cancer research 2004;64(14):4965-72.
2004: Haidong Dong; Gefeng Zhu; Koji Tamada; Dallas B Flies; Jan M A van Deursen; Lieping Chen
B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes.
Immunity 2004;20(3):327-36.
2004: Ryan A Wilcox; Koji Tamada; Dallas B Flies; Gefeng Zhu; Andrei I Chapoval; Bruce R Blazar; W Martin Kast; Lieping Chen
Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo.
Blood 2004;103(1):177-84.
2003: In-Hak Choi; Gefeng Zhu; Gabriel L Sica; Scott E Strome; John C Cheville; Julie S Lau; Yuwen Zhu; Dallas B Flies; Koji Tamada; Lieping Chen
Genomic organization and expression analysis of B7-H4, an immune inhibitory molecule of the B7 family.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4650-4.
2003: Scott E Strome; Haidong Dong; Hideto Tamura; Stephen G Voss; Dallas B Flies; Koji Tamada; Diva R Salomao; John Cheville; Fumiya Hirano; Wei Lin; Jan L Kasperbauer; Karla V Ballman; Lieping Chen
B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma.
Cancer research 2003;63(19):6501-5.
2003: Gabriel L Sica; In-Hak Choi; Gefeng Zhu; Koji Tamada; Shengdian Wang; Hideto Tamura; Andrei I Chapoval; Dallas B Flies; Jürgen Bajorath; Lieping Chen
B7-H4, a molecule of the B7 family, negatively regulates T cell immunity.
Immunity 2003;18(6):849-61.
2003: Shengdian Wang; Jürgen Bajorath; Dallas B Flies; Haidong Dong; Tasuku Honjo; Lieping Chen
Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction.
The Journal of experimental medicine 2003;197(9):1083-91.
2003: Dallas B Flies; Lieping Chen
A simple and rapid vortex method for preparing antigen/adjuvant emulsions for immunization.
Journal of immunological methods 2003;276(1-2):239-42.
2003: Haidong Dong; Scott E Strome; Eric L Matteson; Kevin G Moder; Dallas B Flies; Gefeng Zhu; Hideto Tamura; Colin L W Driscoll; Lieping Chen
Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis.
The Journal of clinical investigation 2003;111(3):363-70.
2002: Ryan A Wilcox; Dallas B Flies; Hao Wang; Koji Tamada; Aaron J Johnson; Larry R Pease; Moses Rodriguez; Yajun Guo; Lieping Chen
Impaired infiltration of tumor-specific cytolytic T cells in the absence of interferon-gamma despite their normal maturation in lymphoid organs during CD137 monoclonal antibody therapy.
Cancer research 2002;62(15):4413-8.
2002: Haidong Dong; Scott E Strome; Diva R Salomao; Hideto Tamura; Fumiya Hirano; Dallas B Flies; Patrick C Roche; Jun Lu; Gefeng Zhu; Koji Tamada; Vanda A Lennon; Esteban Celis; Lieping Chen
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion.
Nature medicine 2002;8(8):793-800.
2002: Ryan A Wilcox; Andrei I Chapoval; Kevin Gorski; Mizuto Otsuji; Tae Kwang Shin; Dallas B Flies; Koji Tamada; Robert S Mittler; Haruo Tsuchiya; Drew M Pardoll; Lieping Chen
Cutting edge: Expression of functional CD137 receptor by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4262-7.
2002: Scott E Strome; Stephen Voss; Ryan Wilcox; TAMEKIA WAKEFIELD; Koji Tamada; Dallas B Flies; Andrei I Chapoval; Jun Lu; Jan L Kasperbauer; Douglas Padley; Richard Vile; Dennis A Gastineau; Peter J Wettstein; Lieping Chen
Strategies for antigen loading of dendritic cells to enhance the antitumor immune response.
Cancer research 2002;62(6):1884-9.
2002: Ryan A Wilcox; Dallas B Flies; Gefeng Zhu; Aaron J Johnson; Koji Tamada; Andrei I Chapoval; Scott E Strome; Larry R Pease; Lieping Chen
Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors.
The Journal of clinical investigation 2002;109(5):651-9.
2002: Scott E Strome; Elizabeth Martin; Dallas B Flies; Dianne Khurana; Diva R Salomao; Koji Tamada; Andrei I Chapoval; Jan L Kasperbauer; Kerry D Olsen; Lieping Chen
Reassessment of CD62L as a marker of pre-effector T cells in the tumor draining lymph nodes of head and neck cancer patients.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2002;126(2):180-7.
2002: Koji Tamada; Hideto Tamura; Dallas B Flies; Yang-Xin Fu; Esteban Celis; Larry R Pease; Bruce R Blazar; Lieping Chen
Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease.
The Journal of clinical investigation 2002;109(4):549-57.
2001: Gefeng Zhu; Dallas B Flies; Koji Tamada; Y Sun; M Rodriguez; Y X Fu; Lieping Chen
Progressive depletion of peripheral B lymphocytes in 4-1BB (CD137) ligand/I-Ealpha)-transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(5):2671-6.
2001: H Tamura; Haidong Dong; Gefeng Zhu; Gabriel L Sica; Dallas B Flies; Koji Tamada; Lieping Chen
B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function.
Blood 2001;97(6):1809-16.
2001: Andrei I Chapoval; J Ni; Julie S Lau; Ryan A Wilcox; Dallas B Flies; D Liu; Haidong Dong; Gabriel L Sica; Gefeng Zhu; Koji Tamada; Lieping Chen
B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production.
Nature immunology 2001;2(3):269-74.
2000: Scott E Strome; B Martin; Dallas B Flies; Koji Tamada; Andrei I Chapoval; D J Sargent; S Shu; Lieping Chen
Enhanced therapeutic potential of adoptive immunotherapy by in vitro CD28/4-1BB costimulation of tumor-reactive T cells against a poorly immunogenic, major histocompatibility complex class I-negative A9P melanoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(4):430-7.
2000: Koji Tamada; K Shimozaki; Andrei I Chapoval; Gefeng Zhu; Gabriel L Sica; Dallas B Flies; T Boone; H Hsu; Y X Fu; S Nagata; J Ni; Lieping Chen
Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway.
Nature medicine 2000;6(3):283-9.