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David Flora

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Chemicals & Drugs

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TOP 3
Fa Liu; Ethan Y Luo; David B Flora; John P Mayer
Concise synthetic routes to human insulin.
Liang Zeng Yan; Hansen M Hsiung; Mark L Heiman; Robert A Gadski; Paul J Emmerson; JeAnne Hertel; David B Flora; Patrick Edwards; David L Smiley; Lianshan Zhang; Saba Husain; Steven D Kahl; Richard D Dimarchi; John P Mayer
Structure-activity relationships of beta-MSH derived melanocortin-4 receptor peptide agonists.
Liang Zeng Yan; David B Flora; Patrick Edwards; David L Smiley; Paul J Emmerson; Hansen M Hsiung; Robert A Gadski; JeAnne Hertel; Mark L Heiman; Saba Husain; Thomas P O'Brien; Steven D Kahl; Lianshan Zhang; Richard D Dimarchi; John P Mayer
Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold.

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All Publications

2013: Fa Liu; Ethan Y Luo; David B Flora; John P Mayer
Concise synthetic routes to human insulin.
Organic letters 2013;15(4):960-3.
2007: Liang Zeng Yan; Hansen M Hsiung; Mark L Heiman; Robert A Gadski; Paul J Emmerson; JeAnne Hertel; David B Flora; Patrick Edwards; David L Smiley; Lianshan Zhang; Saba Husain; Steven D Kahl; Richard D Dimarchi; John P Mayer
Structure-activity relationships of beta-MSH derived melanocortin-4 receptor peptide agonists.
Current topics in medicinal chemistry 2007;7(11):1052-67.
2005: Liang Zeng Yan; David B Flora; Patrick Edwards; David L Smiley; Paul J Emmerson; Hansen M Hsiung; Robert A Gadski; JeAnne Hertel; Mark L Heiman; Saba Husain; Thomas P O'Brien; Steven D Kahl; Lianshan Zhang; Richard D Dimarchi; John P Mayer
Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold.
Bioorganic & medicinal chemistry letters 2005;15(20):4611-4.
2005: John P Mayer; Hansen M Hsiung; David B Flora; Patrick Edwards; Dennis P Smith; Xing-Yue Zhang; Robert A Gadski; Mark L Heiman; JeAnne Hertel; Paul J Emmerson; Saba Husain; Thomas P O'Brien; Steven D Kahl; David L Smiley; Lianshan Zhang; Richard D Dimarchi; Liang Zeng Yan
Discovery of a beta-MSH-derived MC-4R selective agonist.
Journal of medicinal chemistry 2005;48(9):3095-8.
2005: David B Flora; Huaping Mo; John P Mayer; M Amin Khan; Liang Zeng Yan
Detection and control of aspartimide formation in the synthesis of cyclic peptides.
Bioorganic & medicinal chemistry letters 2005;15(4):1065-8.
2002: Matthias H Tschöp; David B Flora; John P Mayer; Mark L Heiman
Hypophysectomy prevents ghrelin-induced adiposity and increases gastric ghrelin secretion in rats.
Obesity research 2002;10(10):991-9.
2002: Mark L Brader; Muppalla Sukumar; Allen H Pekar; David S McClellan; Ronald E Chance; David B Flora; Amy L Cox; Lynnie Irwin; Sharon R Myers
Hybrid insulin cocrystals for controlled release delivery.
Nature biotechnology 2002;20(8):800-4.
1998: J P Richards; MP Stickelmeyer; David B Flora; Ronald E Chance; Bruce Frank; Michael R Defelippis
Self-association properties of monomeric insulin analogs under formulation conditions.
Pharmaceutical research 1998;15(9):1434-41.
1997: Lawrence J Slieker; G S Brooke; Richard D Dimarchi; David B Flora; L K Green; J A Hoffmann; H B Long; L Fan; J E Shields; K L Sundell; PL Surface; Ronald E Chance
Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor.
Diabetologia 1997;40 Suppl 2():S54-61.