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John Floras

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John S Floras
Blood pressure variability: a novel and important risk factor.
Marcel Ruzicka; Andrew J G McReynolds; Elizabeth Coletta; Ross Davies; John S Floras; Haissam Haddad; Frans H H Leenen
Do high doses of AT(1)-receptor blockers attenuate central sympathetic outflow in humans with chronic heart failure?
Takatoshi Kasai; Luigi Taranto Montemurro; Shveta S Motwani; Dai Yumino; Vinoban Amirthalingam; John S Floras; Joseph M Gabriel; T Douglas Bradley
Contrasting effects of lower body positive pressure on upper airways resistance and partial pressure of carbon dioxide in men with heart failure and obstructive or central sleep apnea.

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All Publications

2013: John S Floras
Blood pressure variability: a novel and important risk factor.
The Canadian journal of cardiology 2013;29(5):557-63.
2013: Marcel Ruzicka; Andrew J G McReynolds; Elizabeth Coletta; Ross Davies; John S Floras; Haissam Haddad; Frans H H Leenen
Do high doses of AT(1)-receptor blockers attenuate central sympathetic outflow in humans with chronic heart failure?
Clinical science (London, England : 1979) 2013;124(9):589-95.
2013: Takatoshi Kasai; Luigi Taranto Montemurro; Shveta S Motwani; Dai Yumino; Vinoban Amirthalingam; John S Floras; Joseph M Gabriel; T Douglas Bradley
Contrasting effects of lower body positive pressure on upper airways resistance and partial pressure of carbon dioxide in men with heart failure and obstructive or central sleep apnea.
Journal of the American College of Cardiology 2013;61(11):1157-66.
2013: Dai Yumino; Vinoban Amirthalingam; John S Floras; Takatoshi Kasai; Derek Kimmerly; T Douglas Bradley
Differing effects of obstructive and central sleep apneas on stroke volume in patients with heart failure.
American journal of respiratory and critical care medicine 2013;187(4):433-8.
2013: Cheri L McGowan; Philip J Millar; Beverley L Morris; Hisayoshi Murai; Catherine F Notarius; John S Floras
Simvastatin reduces sympathetic outflow and augments endothelium-independent dilation in non-hyperlipidaemic primary hypertension.
Heart (British Cardiac Society) 2013;99(4):240-6.
2013: Alexandros Kasiakogias; Vasilios Papademetriou; Manos Alchanatis; Dimitrios Aragiannis; John S Floras; Costas Thomopoulos; Dimitrios Tousoulis; Costas Tsioufis; Christodoulos Stefanadis
Effects of continuous positive airway pressure on blood pressure in hypertensive patients with obstructive sleep apnea: a 3-year follow-up.
Journal of hypertension 2013;31(2):352-60.
2013: John S Floras; JoAnne Arcand
Neurocirculatory responses to carbohydrates in patients with heart failure and healthy controls: more similar than different.
The Canadian journal of cardiology 2013;29(2):144-6.
2012: Luigi Taranto Montemurro; Fernando Morgadinho S Coelho; John S Floras; Joseph M Gabriel; Takatoshi Kasai; Philip J Millar; Jonas Spaak; T Douglas Bradley
Inverse relationship of subjective daytime sleepiness to sympathetic activity in patients with heart failure and obstructive sleep apnea.
Chest 2012;142(5):1222-8.
2012: Takatoshi Kasai; John S Floras; T Douglas Bradley
Sleep apnea and cardiovascular disease: a bidirectional relationship.
Circulation 2012;126(12):1495-510.
2012: Frans H H Leenen; Marcel Ruzicka; John S Floras
Central sympathetic inhibition by mineralocorticoid receptor but not angiotensin II type 1 receptor blockade: are prescribed doses too low?
Hypertension 2012;60(2):278-80.
2012: Peter C Papageorgiou; Erik L Yeo; Peter H Backx; John S Floras
Activated plasma coagulation β-Factor XII-induced vasoconstriction in rats.
Clinical science (London, England : 1979) 2012;122(12):581-90.
2012: John S Floras
B-type natriuretic peptide-guided hypertension management?
Journal of hypertension 2012;30(5):890-2.
2012: K Nair; J Asta; T Farid; John S Floras; J Jacob; M Kusha; S Masse; K Poku; Elias Sevaptsidis; K Umapathy; S Watkins; Kumaraswamy Nanthakumar
Studying semblances of a true killer: experimental model of human ventricular fibrillation.
American journal of physiology. Heart and circulatory physiology 2012;302(7):H1533-7.
2012: John S Floras
Transvenous phrenic nerve stimulation for central sleep apnoea in heart failure: chicken or egg?
European heart journal 2012;33(7):810-2.
2012: Peter C Papageorgiou; Erik L Yeo; Peter H Backx; John S Floras
A new enzyme-linked immunosorbent assay recognizing both rat and human activated coagulation Factor XII (FXIIa).
Journal of immunological methods 2012;376(1-2):132-8.
2012: Catherine F Notarius; Beverley L Morris; Hisayoshi Murai; John S Floras
Effect of fitness on reflex sympathetic neurovascular transduction in middle-age men.
Medicine and science in sports and exercise 2012;44(2):232-7.
2011: Paul J Galiwango; Joan Ivanov; Andrew McReynolds; Chris T Chan; John S Floras
Activity with ambulation attenuates diuretic responsiveness in chronic heart failure.
Journal of cardiac failure 2011;17(10):797-803.
2011: Philip J Millar; Hisayoshi Murai; John S Floras
Neurogenic retrograde arterial flow during obstructive sleep apnea: a novel mechanism for endothelial dysfunction?
Hypertension 2011;58(3):e17-8.
2011: Harindra C Wijeysundera; Gurpreet Parmar; Gerard A Rongen; John S Floras
Reflex systemic sympatho-neural response to brachial adenosine infusion in treated heart failure.
European journal of heart failure 2011;13(5):475-81.
2011: Cheri L McGowan; Catherine F Notarius; Andrew McReynolds; Beverley L Morris; Derek S Kimmerly; Peter Picton; John S Floras
Effect of angiotensin AT1 receptor blockade on sympathetic responses to handgrip in healthy men.
American journal of hypertension 2011;24(5):537-43.
2011: JoAnne Arcand; John S Floras; Eduardo Azevedo; Susanna Mak; Gary E Newton; Johane P Allard
Evaluation of 2 methods for sodium intake assessment in cardiac patients with and without heart failure: the confounding effect of loop diuretics.
The American journal of clinical nutrition 2011;93(3):535-41.
2011: Dai Yumino; Hanqiao Wang; John S Floras; Gary E Newton; Susanna Mak; Pimon Ruttanaumpawan; John D Parker; T Douglas Bradley
Relation of periodic leg movements during sleep and mortality in patients with systolic heart failure.
The American journal of cardiology 2011;107(3):447-51.
2011: Toshihiko Kubo; Eduardo R Azevedo; Gary E Newton; Peter Picton; John D Parker; John S Floras
β-blockade restores muscle sympathetic rhythmicity in human heart failure.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(6):1400-8.
2010: Catherine F Notarius; John S Floras
Muscle metaboreflex and exercise heart rate: insights from studies in subjects with and without heart failure.
The Journal of physiology 2010;588(Pt 14):2679; author reply 2681.
2010: Jonas Spaak; George Tomlinson; Cheri L McGowan; George J Soleas; Beverley L Morris; Peter Picton; Catherine F Notarius; John S Floras
Dose-related effects of red wine and alcohol on heart rate variability.
American journal of physiology. Heart and circulatory physiology 2010;298(6):H2226-31.
2010: Robert P Nolan; John S Floras; Paula J Harvey; Markad V Kamath; Peter Picton; Caroline Chessex; Natalie Hiscock; Jonathan Powell; Michael Catt; Hilde Hendrickx; Duncan Talbot; Maggie H Chen
Behavioral neurocardiac training in hypertension: a randomized, controlled trial.
Hypertension 2010;55(4):1033-9.
2010: Clodagh M Ryan; John S Floras; Alexander G Logan; R John Kimoff; Frederic Series; Debra Morrison; K A Ferguson; I Belenkie; M Pfeifer; John A Fleetham; Patrick J Hanly; Mark Smilovitch; Michael Arzt; T Douglas Bradley
Shift in sleep apnoea type in heart failure patients in the CANPAP trial.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010;35(3):592-7.
2009: Douglas S Lee; Nina Ghosh; John S Floras; Gary E Newton; Peter C Austin; Xuesong Wang; Peter P Liu; Thérèse A Stukel; Jack V Tu
Association of blood pressure at hospital discharge with mortality in patients diagnosed with heart failure.
Circulation. Heart failure 2009;2(6):616-23.
2009: Catherine F Notarius; Beverley L Morris; John S Floras
Dissociation between reflex sympathetic and forearm vascular responses to lower body negative pressure in heart failure patients with coronary artery disease.
American journal of physiology. Heart and circulatory physiology 2009;297(5):H1760-6.
2009: John S Floras
Sympathetic nervous system activation in human heart failure: clinical implications of an updated model.
Journal of the American College of Cardiology 2009;54(5):375-85.
2009: John S Floras; Susanna Mak
Muscle sympathetic nerve activity in women and men following acute myocardial infarction: a meaningful difference?
European heart journal 2009;30(14):1692-4.
2009: John S Floras
Should sleep apnoea be a specific target of therapy in chronic heart failure?
Heart (British Cardiac Society) 2009;95(13):1041-6.
2009: Dai Yumino; Hanqiao Wang; John S Floras; Gary E Newton; Susanna Mak; Pimon Ruttanaumpawan; John D Parker; T Douglas Bradley
Prevalence and physiological predictors of sleep apnea in patients with heart failure and systolic dysfunction.
Journal of cardiac failure 2009;15(4):279-85.
2009: C L McGowan; J S Swiston; Catherine F Notarius; S Mak; Beverley L Morris; Peter Picton; J T Granton; John S Floras
Discordance between microneurographic and heart-rate spectral indices of sympathetic activity in pulmonary arterial hypertension.
Heart (British Cardiac Society) 2009;95(9):754-8.
2009: Dai Yumino; H Wang; John S Floras; Gary E Newton; Susanna Mak; Pimon Ruttanaumpawan; John D Parker; T Douglas Bradley
Relationship between sleep apnoea and mortality in patients with ischaemic heart failure.
Heart (British Cardiac Society) 2009;95(10):819-24.
2009: T Douglas Bradley; John S Floras
Obstructive sleep apnoea and its cardiovascular consequences.
Lancet 2009;373(9657):82-93.
2009: Pimon Ruttanaumpawan; Alexander G Logan; John S Floras; T Douglas Bradley
Effect of continuous positive airway pressure on sleep structure in heart failure patients with central sleep apnea.
Sleep 2009;32(1):91-8.
2008: Virend K Somers; David P White; Raouf Amin; William T Abraham; Fernando Costa; Antonio Culebras; Stephen Daniels; John S Floras; Carl E Hunt; Lyle J Olson; Thomas G Pickering; Richard Russell; Mary Woo; Terry Young
Sleep apnea and cardiovascular disease: an American Heart Association/american College Of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council On Cardiovascular Nursing. In collaboration with the National Heart, Lung, and Blood Institute National Center on Sleep Disorders Research (National Institutes of Health).
Circulation 2008;118(10):1080-111.
2008: Philip Jong; John S Floras; Robert P Nolan
Letter by Jong et al regarding article, "dietary fish and omega-3 fatty acid consumption and heart rate variability in US adults".
Circulation 2008;118(8):e129; author reply e130.
2008: Virend K Somers; David P White; Raouf Amin; William T Abraham; Fernando Costa; Antonio Culebras; Stephen Daniels; John S Floras; Carl E Hunt; Lyle J Olson; Thomas G Pickering; Richard Russell; Mary Woo; Terry Young
Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing.
Journal of the American College of Cardiology 2008;52(8):686-717.
2008: Robert P Nolan; Philip Jong; Susan M Barry-Bianchi; Tim H Tanaka; John S Floras
Effects of drug, biobehavioral and exercise therapies on heart rate variability in coronary artery disease: a systematic review.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2008;15(4):386-96.
2008: Pimon Ruttanaumpawan; Matthew P Gilman; Kengo Usui; John S Floras; T Douglas Bradley
Sustained effect of continuous positive airway pressure on baroreflex sensitivity in congestive heart failure patients with obstructive sleep apnea.
Journal of hypertension 2008;26(6):1163-8.
2008: Klaus K A Witte; Catherine F Notarius; Joan Ivanov; John S Floras
Muscle sympathetic nerve activity and ventilation during exercise in subjects with and without chronic heart failure.
The Canadian journal of cardiology 2008;24(4):275-8.
2008: Jonas Spaak; Anthony C Merlocco; George J Soleas; George Tomlinson; Beverley L Morris; Peter Picton; Catherine F Notarius; Christopher T Chan; John S Floras
Dose-related effects of red wine and alcohol on hemodynamics, sympathetic nerve activity, and arterial diameter.
American journal of physiology. Heart and circulatory physiology 2008;294(2):H605-12.
2008: Matthew P Gilman; John S Floras; Kengo Usui; Yasuyuki Kaneko; Richard S T Leung; T Douglas Bradley
Continuous positive airway pressure increases heart rate variability in heart failure patients with obstructive sleep apnoea.
Clinical science (London, England : 1979) 2008;114(3):243-9.
2008: Akis A Amfilochiadis; Peter H Backx; John S Floras
Adrenomedullary catecholamine, pressor and chronotropic responses to human coagulation beta-FXIIa mediated by endogenous kinins.
Journal of hypertension 2008;26(1):61-9.
2007: Christopher T Chan; Catherine F Notarius; Anthony C Merlocco; John S Floras
Improvement in exercise duration and capacity after conversion to nocturnal home haemodialysis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(11):3285-91.
2007: Satomi Shiota; Clodagh M Ryan; Kuo-Liang Chiu; Pimon Ruttanaumpawan; James Haight; Michael Arzt; John S Floras; Christopher Chan; T Douglas Bradley
Alterations in upper airway cross-sectional area in response to lower body positive pressure in healthy subjects.
Thorax 2007;62(10):868-72.
2007: Catherine F Notarius; Jonas Spaak; Beverley L Morris; John S Floras
Comparison of muscle sympathetic activity in ischemic and nonischemic heart failure.
Journal of cardiac failure 2007;13(6):470-5.
2007: John S Floras
Ambulatory blood pressure: facilitating individualized assessment of cardiovascular risk.
Journal of hypertension 2007;25(8):1565-8.
2007: John S Floras; T Douglas Bradley
Treating obstructive sleep apnea: is there more to the story than 2 millimeters of mercury?
Hypertension 2007;50(2):289-91.
2007: Michael Arzt; John S Floras; Alexander G Logan; R John Kimoff; Frederic Series; Debra Morrison; Kathy Ferguson; Israel Belenkie; Michael Pfeifer; John A Fleetham; Patrick J Hanly; Mark Smilovitch; Clodagh Ryan; George Tomlinson; T Douglas Bradley
Suppression of central sleep apnea by continuous positive airway pressure and transplant-free survival in heart failure: a post hoc analysis of the Canadian Continuous Positive Airway Pressure for Patients with Central Sleep Apnea and Heart Failure Trial (CANPAP).
Circulation 2007;115(25):3173-80.
2007: Catherine F Notarius; John S Floras
Comment on point:counterpoint: "cardiovascular variability is/is not an index of autonomic control of circulation".
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(6):2406.
2007: Hanqiao Wang; John D Parker; Gary E Newton; John S Floras; Susanna Mak; Kuo-Liang Chiu; Pimon Ruttanaumpawan; George Tomlinson; T Douglas Bradley
Influence of obstructive sleep apnea on mortality in patients with heart failure.
Journal of the American College of Cardiology 2007;49(15):1625-31.
2007: Catherine F Notarius; John S Floras
Point:counterpoint: Increased mechanoreceptor/metaboreceptor stimulation explains the exaggerated exercise pressor reflex seen in heart failure.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(2):824.
2006: Kuo-Liang Chiu; Clodagh M Ryan; Satomi Shiota; Pimon Ruttanaumpawan; Michael Arzt; James S Haight; Christopher T Chan; John S Floras; T Douglas Bradley
Fluid shift by lower body positive pressure increases pharyngeal resistance in healthy subjects.
American journal of respiratory and critical care medicine 2006;174(12):1378-83.
2006: Abdul Al-Hesayen; John S Floras; John D Parker
The effects of intravenous sildenafil on hemodynamics and cardiac sympathetic activity in chronic human heart failure.
European journal of heart failure 2006;8(8):864-8.
2006: Michael Arzt; Terry Young; Laurel Finn; James B Skatrud; Clodagh M Ryan; Gary E Newton; Susanna Mak; John D Parker; John S Floras; T Douglas Bradley
Sleepiness and sleep in patients with both systolic heart failure and obstructive sleep apnea.
Archives of internal medicine 2006;166(16):1716-22.
2006: Kengo Usui; John D Parker; Gary E Newton; John S Floras; Clodagh M Ryan; T Douglas Bradley
Left ventricular structural adaptations to obstructive sleep apnea in dilated cardiomyopathy.
American journal of respiratory and critical care medicine 2006;173(10):1170-5.
2006: Catherine F Notarius; Beverley Morris; John S Floras
Caffeine prolongs exercise duration in heart failure.
Journal of cardiac failure 2006;12(3):220-6.
2006: John S Floras; Catherine F Notarius; Paula J Harvey
Exercise training--not a class effect: blood pressure more buoyant after swimming than walking.
Journal of hypertension 2006;24(2):269-72.
2006: Catherine F Notarius; Beverley L Morris; John S Floras
Caffeine attenuates early post-exercise hypotension in middle-aged subjects.
American journal of hypertension 2006;19(2):184-8.
2006: Richard S T Leung; John S Floras; T Douglas Bradley
Respiratory modulation of the autonomic nervous system during Cheyne-Stokes respiration.
Canadian journal of physiology and pharmacology 2006;84(1):61-6.
2005: John S Floras
Sleep apnea in heart failure: implications of sympathetic nervous system activation for disease progression and treatment.
Current heart failure reports 2005;2(4):212-7.
2005: Christopher T Chan; Paula J Harvey; Rainer Böger; Andreas Pierratos; John S Floras
Dissociation between the short-term effects of nocturnal hemodialysis on endothelium dependent vasodilation and plasma ADMA.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(12):2685-6.
2005: Jonas Spaak; Zoltan J Egri; Toshihiko Kubo; Eric Yu; Shin-Ichi Ando; Yasuyuki Kaneko; Kengo Usui; T Douglas Bradley; John S Floras
Muscle sympathetic nerve activity during wakefulness in heart failure patients with and without sleep apnea.
Hypertension 2005;46(6):1327-32.
2005: John S Floras
Atrial fibrillation and cardiac sympathetic reflexes in heart failure.
European heart journal 2005;26(23):2490-2.
2005: T Douglas Bradley; Alexander G Logan; R John Kimoff; Frédéric Sériès; Debra Morrison; Kathy Ferguson; Israel Belenkie; Michael Pfeifer; John A Fleetham; Patrick J Hanly; Mark Smilovitch; George Tomlinson; John S Floras
Continuous positive airway pressure for central sleep apnea and heart failure.
The New England journal of medicine 2005;353(19):2025-33.
2005: Richard S T Leung; Michael E Bowman; Tung M Diep; Geraldo Lorenzi-Filho; John S Floras; T Douglas Bradley
Influence of Cheyne-Stokes respiration on ventricular response to atrial fibrillation in heart failure.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(5):1689-96.
2005: C M Ryan; K Usui; John S Floras; T Douglas Bradley
Effect of continuous positive airway pressure on ventricular ectopy in heart failure patients with obstructive sleep apnoea.
Thorax 2005;60(9):781-5.
2005: Toshihiko Kubo; John D Parker; Eduardo R Azevedo; Deborah J Atchison; Gary E Newton; Peter Picton; John S Floras
Vagal heart rate responses to chronic beta-blockade in human heart failure relate to cardiac norepinephrine spillover.
European journal of heart failure 2005;7(5):878-81.
2005: John S Floras; T Douglas Bradley
Atrial overdrive pacing for sleep apnea: a door now closed?
American journal of respiratory and critical care medicine 2005;172(1):1-3.
2005: Christopher T Chan; Vipan Jain; Peter Picton; Andreas Pierratos; John S Floras
Nocturnal hemodialysis increases arterial baroreflex sensitivity and compliance and normalizes blood pressure of hypertensive patients with end-stage renal disease.
Kidney international 2005;68(1):338-44.
2005: Kengo Usui; T Douglas Bradley; Jonas Spaak; Clodagh M Ryan; Toshihiko Kubo; Yasuyuki Kaneko; John S Floras
Inhibition of awake sympathetic nerve activity of heart failure patients with obstructive sleep apnea by nocturnal continuous positive airway pressure.
Journal of the American College of Cardiology 2005;45(12):2008-11.
2005: Robert P Nolan; Markad V Kamath; John S Floras; Jill Stanley; Clement Pang; Peter Picton; Quincy R Young
Heart rate variability biofeedback as a behavioral neurocardiac intervention to enhance vagal heart rate control.
American heart journal 2005;149(6):1137.
2005: Abdul Al-Hesayen; Eduardo R Azevedo; John S Floras; Shauna Hollingshead; Gary D Lopaschuk; John D Parker
Selective versus nonselective beta-adrenergic receptor blockade in chronic heart failure: differential effects on myocardial energy substrate utilization.
European journal of heart failure 2005;7(4):618-23.
2005: Frédéric Sériès; R John Kimoff; Debra Morrison; Marie-Helene Leblanc; Mark Smilovitch; Jonathan G Howlett; Alexander G Logan; John S Floras; T Douglas Bradley
Prospective evaluation of nocturnal oximetry for detection of sleep-related breathing disturbances in patients with chronic heart failure.
Chest 2005;127(5):1507-14.
2005: Paula J Harvey; Beverley L Morris; Judith A Miller; John S Floras
Estradiol induces discordant angiotensin and blood pressure responses to orthostasis in healthy postmenopausal women.
Hypertension 2005;45(3):399-405.
2005: Paula J Harvey; Peter Picton; Winnie S Su; Beverley L Morris; Catherine F Notarius; John S Floras
Exercise as an alternative to oral estrogen for amelioration of endothelial dysfunction in postmenopausal women.
American heart journal 2005;149(2):291-7.
2005: Paula J Harvey; Beverley L Morris; Toshihiko Kubo; Peter Picton; Winnie S Su; Catherine F Notarius; John S Floras
Hemodynamic after-effects of acute dynamic exercise in sedentary normotensive postmenopausal women.
Journal of hypertension 2005;23(2):285-92.
2004: Tommaso Gori; Paula Harvey; John S Floras; John D Parker
Continuous therapy with nitroglycerin impairs endothelium-dependent vasodilation but does not cause tolerance in conductance arteries: a human in vivo study.
Journal of cardiovascular pharmacology 2004;44(5):601-6.
2004: Christopher T Chan; Patrick J Hanly; Jonathan Y Gabor; Peter Picton; Andreas Pierratos; John S Floras
Impact of nocturnal hemodialysis on the variability of heart rate and duration of hypoxemia during sleep.
Kidney international 2004;65(2):661-5.
2004: Sindhu R Johnson; P J Harvey; John S Floras; M Iwanochko; Dominique Ibanez; Dafna D Gladman; Murray B Urowitz
Impaired brachial artery endothelium dependent flow mediated dilation in systemic lupus erythematosus: preliminary observations.
Lupus 2004;13(8):590-3.
2003: Christopher T Chan; Paula J Harvey; Peter Picton; Andreas Pierratos; Judith A Miller; John S Floras
Short-term blood pressure, noradrenergic, and vascular effects of nocturnal home hemodialysis.
Hypertension 2003;42(5):925-31.
2003: Catherine F Notarius; Gerard A Rongen; John S Floras
Caffeine and coffee tolerance.
Circulation 2003;108(6):e38-40; author reply e38-40.
2003: Richard S T Leung; John S Floras; Geraldo Lorenzi-Filho; Fiona Rankin; Peter Picton; T Douglas Bradley
Influence of Cheyne-Stokes respiration on cardiovascular oscillations in heart failure.
American journal of respiratory and critical care medicine 2003;167(11):1534-9.
2003: Don D Sin; Fabia Fitzgerald; John D Parker; Gary E Newton; Alexander G Logan; John S Floras; T Douglas Bradley
Relationship of systolic BP to obstructive sleep apnea in patients with heart failure.
Chest 2003;123(5):1536-43.
2003: T Douglas Bradley; John S Floras
Sleep apnea and heart failure: Part II: central sleep apnea.
Circulation 2003;107(13):1822-6.
2003: T Douglas Bradley; John S Floras
Sleep apnea and heart failure: Part I: obstructive sleep apnea.
Circulation 2003;107(12):1671-8.
2003: Yasuyuki Kaneko; John S Floras; Kengo Usui; Julie Plante; Ruzena Tkacova; Toshihiko Kubo; Shin-ichi Ando; T Douglas Bradley
Cardiovascular effects of continuous positive airway pressure in patients with heart failure and obstructive sleep apnea.
The New England journal of medicine 2003;348(13):1233-41.
2003: John S Floras
Sympathetic activation in human heart failure: diverse mechanisms, therapeutic opportunities.
Acta physiologica Scandinavica 2003;177(3):391-8.
2003: T Douglas Bradley; Ruzena Tkacova; Michael J Hall; Shin-ichi Ando; John S Floras
Augmented sympathetic neural response to simulated obstructive apnoea in human heart failure.
Clinical science (London, England : 1979) 2003;104(3):231-8.
2003: Alexander G Logan; Ruzena Tkacova; S M Perlikowski; Richard S T Leung; András Tislér; John S Floras; T Douglas Bradley
Refractory hypertension and sleep apnoea: effect of CPAP on blood pressure and baroreflex.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;21(2):241-7.
2002: Tommaso Gori; John S Floras; John D Parker
Effects of nitroglycerin treatment on baroreflex sensitivity and short-term heart rate variability in humans.
Journal of the American College of Cardiology 2002;40(11):2000-5.
2002: Christopher Chan; John S Floras; Judith A Miller; Andreas Pierratos
Improvement in ejection fraction by nocturnal haemodialysis in end-stage renal failure patients with coexisting heart failure.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(8):1518-21.
2002: Christopher T Chan; John S Floras; Judith A Miller; Robert M A Richardson; Andreas Pierratos
Regression of left ventricular hypertrophy after conversion to nocturnal hemodialysis.
Kidney international 2002;61(6):2235-9.
2002: John S Floras
Morning activity and blood pressure--a cause for concern?
Journal of hypertension 2002;20(5):809-11.
2002: Catherine F Notarius; E R Azevedo; John D Parker; John S Floras
Peak oxygen uptake is not determined by cardiac noradrenaline spillover in heart failure.
European heart journal 2002;23(10):800-5.
2002: John S Floras
The "unsympathetic" nervous system of heart failure.
Circulation 2002;105(15):1753-5.
2002: John S Floras
Vasopeptidase inhibition: a novel approach to cardiovascular therapy.
The Canadian journal of cardiology 2002;18(2):177-82.
2002: Mala Chidambaram; John A Duncan; Vesta Lai; Daniel C Cattran; John S Floras; James W Scholey; Judith A Miller
Variation in the renin angiotensin system throughout the normal menstrual cycle.
Journal of the American Society of Nephrology : JASN 2002;13(2):446-52.
2001: Toshihiko Kubo; Eduardo R Azevedo; Gary E Newton; John D Parker; John S Floras
Lack of evidence for peripheral alpha(1)- adrenoceptor blockade during long-term treatment of heart failure with carvedilol.
Journal of the American College of Cardiology 2001;38(5):1463-9.
2001: Eduardo R Azevedo; T Kubo; Susanna Mak; Abdul Al-Hesayen; A Schofield; R Allan; S Kelly; Gary E Newton; John S Floras; John D Parker
Nonselective versus selective beta-adrenergic receptor blockade in congestive heart failure: differential effects on sympathetic activity.
Circulation 2001;104(18):2194-9.
2001: Catherine F Notarius; D J Atchison; Gerard A Rongen; John S Floras
Effect of adenosine receptor blockade with caffeine on sympathetic response to handgrip exercise in heart failure.
American journal of physiology. Heart and circulatory physiology 2001;281(3):H1312-8.
2001: John S Floras; GC Butler; S i Ando; Steven Brooks; MJ Pollard; Peter Picton
Differential sympathetic nerve and heart rate spectral effects of nonhypotensive lower body negative pressure.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(2):R468-75.
2001: T Douglas Bradley; Alexander G Logan; John S Floras
Rationale and design of the Canadian Continuous Positive Airway Pressure Trial for Congestive Heart Failure patients with Central Sleep Apnea--CANPAP.
The Canadian journal of cardiology 2001;17(6):677-84.
2001: T Douglas Bradley; M J Hall; S Ando ; John S Floras
Hemodynamic effects of simulated obstructive apneas in humans with and without heart failure.
Chest 2001;119(6):1827-35.
2001: Toshihiko Kubo; S i Ando; Peter Picton; D J Atchison; Catherine F Notarius; MJ Pollard; BL Abramson; John S Floras
Atrial natriuretic peptide augments the variability of sympathetic nerve activity in human heart failure.
Journal of hypertension 2001;19(3 Pt 2):619-26.
2001: D N Wijeysundera; GC Butler; S i Ando; M Pollard; Peter Picton; John S Floras
Attenuated cardiac baroreflex in men with presyncope evoked by lower body negative pressure.
Clinical science (London, England : 1979) 2001;100(3):303-9.
2001: Catherine F Notarius; D J Atchison; John S Floras
Impact of heart failure and exercise capacity on sympathetic response to handgrip exercise.
American journal of physiology. Heart and circulatory physiology 2001;280(3):H969-76.
2001: Amrit K Kang; John A Duncan; Daniel C Cattran; John S Floras; Vesta Lai; James W Scholey; Judith A Miller
Effect of oral contraceptives on the renin angiotensin system and renal function.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(3):R807-13.
2001: Catherine F Notarius; John S Floras
Limitations of the use of spectral analysis of heart rate variability for the estimation of cardiac sympathetic activity in heart failure.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2001;3(1):29-38.
2000: Gerard A Rongen; J W Lenders; P Smits; John S Floras
Comparison of two indices for forearm noradrenaline release in humans.
Clinical science (London, England : 1979) 2000;99(5):363-9.
2000: Ruzena Tkacova; Hilmi R Dajani; Fiona Rankin; Fabia Fitzgerald; John S Floras; T Douglas Bradley
Continuous positive airway pressure improves nocturnal baroreflex sensitivity of patients with heart failure and obstructive sleep apnea.
Journal of hypertension 2000;18(9):1257-62.
2000: Eduardo R Azevedo; Gary E Newton; John S Floras; John D Parker
Reducing cardiac filling pressure lowers norepinephrine spillover in patients with chronic heart failure.
Circulation 2000;101(17):2053-9.
2000: Eduardo R Azevedo; Gary E Newton; AB Parker; John S Floras; John D Parker
Sympathetic responses to atrial natriuretic peptide in patients with congestive heart failure.
Journal of cardiovascular pharmacology 2000;35(1):129-35.
1999: Don D Sin; Fabia Fitzgerald; John D Parker; G Newton; John S Floras; T Douglas Bradley
Risk factors for central and obstructive sleep apnea in 450 men and women with congestive heart failure.
American journal of respiratory and critical care medicine 1999;160(4):1101-6.
1999: Gerard A Rongen; Steven Brooks; MJ Pollard; S i Ando; Hilmi R Dajani; Catherine F Notarius; John S Floras
Effect of adenosine on heart rate variability in humans.
Clinical science (London, England : 1979) 1999;96(6):597-604.
1999: Catherine F Notarius; GC Butler; S i Ando; MJ Pollard; B L Senn; John S Floras
Dissociation between microneurographic and heart rate variability estimates of sympathetic tone in normal subjects and patients with heart failure.
Clinical science (London, England : 1979) 1999;96(6):557-65.
1999: Catherine F Notarius; S Ando; Gerard A Rongen; John S Floras
Resting muscle sympathetic nerve activity and peak oxygen uptake in heart failure and normal subjects.
European heart journal 1999;20(12):880-7.
1999: BL Abramson; S i Ando; Catherine F Notarius; Gerard A Rongen; John S Floras
Effect of atrial natriuretic peptide on muscle sympathetic activity and its reflex control in human heart failure.
Circulation 1999;99(14):1810-5.
1999: Dina Brooks; Richard L Horner; John S Floras; Louise F Kozar; CL Render-Teixeira; Eliot A Phillipson
Baroreflex control of heart rate in a canine model of obstructive sleep apnea.
American journal of respiratory and critical care medicine 1999;159(4 Pt 1):1293-7.
1999: Geraldo Lorenzi-Filho; Hilmi R Dajani; Richard S T Leung; John S Floras; T Douglas Bradley
Entrainment of blood pressure and heart rate oscillations by periodic breathing.
American journal of respiratory and critical care medicine 1999;159(4 Pt 1):1147-54.
1998: Ruzena Tkacova; Fiona Rankin; Fabia Fitzgerald; John S Floras; T Douglas Bradley
Effects of continuous positive airway pressure on obstructive sleep apnea and left ventricular afterload in patients with heart failure.
Circulation 1998;98(21):2269-75.
1998: Gerard A Rongen; Steven Brooks; S i Ando; Catherine F Notarius; John S Floras
Caffeine abstinence augments the systolic blood pressure response to adenosine in humans.
The American journal of cardiology 1998;81(11):1382-5.
1998: K Hara; John S Floras
Resting muscle sympathetic nerve activity does not predict duration of symptom-limited submaximal exercise in young patients with dilated cardiomyopathy.
The Canadian journal of cardiology 1998;14(5):689-94.
1998: Gerard A Rongen; Steven Brooks; S i Ando; BL Abramson; John S Floras
Angiotensin AT1 receptor blockade abolishes the reflex sympatho-excitatory response to adenosine.
The Journal of clinical investigation 1998;101(4):769-76.
1998: Gerard A Rongen; Steven Brooks; S i Ando; Hilmi R Dajani; BL Abramson; John S Floras
Neural and hypotensive effects of angiotensin II receptor blockade.
Hypertension 1998;31(1 Pt 2):378-83.
1997: S i Ando; Hilmi R Dajani; John S Floras
Frequency domain characteristics of muscle sympathetic nerve activity in heart failure and healthy humans.
The American journal of physiology 1997;273(1 Pt 2):R205-12.
1997: GC Butler; S i Ando; John S Floras
Fractal component of variability of heart rate and systolic blood pressure in congestive heart failure.
Clinical science (London, England : 1979) 1997;92(6):543-50.
1997: Gerard A Rongen; B L Senn; S i Ando; Catherine F Notarius; J A Stone; John S Floras
Comparison of hemodynamic and sympathoneural responses to adenosine and lower body negative pressure in man.
Canadian journal of physiology and pharmacology 1997;75(2):128-34.
1997: S i Ando; Hilmi R Dajani; B L Senn; Gary E Newton; John S Floras
Sympathetic alternans. Evidence for arterial baroreflex control of muscle sympathetic nerve activity in congestive heart failure.
Circulation 1997;95(2):316-9.
1997: Gerard A Rongen; John S Floras; Jacques W M Lenders; Theo Thien; Paul Smits
Cardiovascular pharmacology of purines.
Clinical science (London, England : 1979) 1997;92(1):13-24.
1996: M J Hall; A Xie; R Rutherford; S Ando; John S Floras; T Douglas Bradley
Cycle length of periodic breathing in patients with and without heart failure.
American journal of respiratory and critical care medicine 1996;154(2 Pt 1):376-81.
1996: Gary E Newton; J H Tong; A M Schofield; A D Baines; John S Floras; John D Parker
Digoxin reduces cardiac sympathetic activity in severe congestive heart failure.
Journal of the American College of Cardiology 1996;28(1):155-61.
1996: Judith A Miller; John S Floras; Bernard Zinman; K L Skorecki; A G Logan
Effect of hyperglycaemia on arterial pressure, plasma renin activity and renal function in early diabetes.
Clinical science (London, England : 1979) 1996;90(3):189-95.
1995: S i Ando; M A Rahman; GC Butler; B L Senn; John S Floras
Comparison of candoxatril and atrial natriuretic factor in healthy men. Effects on hemodynamics, sympathetic activity, heart rate variability, and endothelin.
Hypertension 1995;26(6 Pt 2):1160-6.
1995: John D Parker; Gary E Newton; J S Landzberg; John S Floras; W S Colucci
Functional significance of presynaptic alpha-adrenergic receptors in failing and nonfailing human left ventricle.
Circulation 1995;92(7):1793-800.
1995: John S Floras
Inhibitory effect of atrial natriuretic factor on sympathetic ganglionic neurotransmission in humans.
The American journal of physiology 1995;269(2 Pt 2):R406-12.
1995: X Chen; M A Rahman; John S Floras
Effects of forearm venous occlusion on peroneal muscle sympathetic nerve activity in healthy subjects.
The American journal of cardiology 1995;76(3):212-4.
1995: GC Butler; B L Senn; John S Floras
Influence of atrial natriuretic factor on spontaneous baroreflex sensitivity for heart rate in humans.
Hypertension 1995;25(6):1167-71.
1995: M Maingi; M F Glynn; Hugh E Scully; A F Graham; John S Floras
Spontaneous spinal epidural hematoma in a patient with a mechanical aortic valve taking warfarin.
The Canadian journal of cardiology 1995;11(5):429-32.
1995: K Hara; B M Senn; John S Floras
Evaluation of acute haemodynamic response to high-dose naloxone in young hypertensive and normotensive humans.
Clinical and investigative medicine. Médecine clinique et experimentale 1995;18(2):108-13.
1995: K Hara; John S Floras
Influence of naloxone on muscle sympathetic nerve activity, systemic and calf haemodynamics and ambulatory blood pressure after exercise in mild essential hypertension.
Journal of hypertension 1995;13(4):447-61.
1995: Matthew Thomas Naughton; M A Rahman; K Hara; John S Floras; T Douglas Bradley
Effect of continuous positive airway pressure on intrathoracic and left ventricular transmural pressures in patients with congestive heart failure.
Circulation 1995;91(6):1725-31.
1995: GC Butler; Matthew Thomas Naughton; M A Rahman; T Douglas Bradley; John S Floras
Continuous positive airway pressure increases heart rate variability in congestive heart failure.
Journal of the American College of Cardiology 1995;25(3):672-9.
1994: GC Butler; B L Senn; John S Floras
Influence of atrial natriuretic factor on heart rate variability in normal men.
The American journal of physiology 1994;267(2 Pt 2):H500-5.
1994: Judith A Miller; John S Floras; Bernard Zinman; K L Skorecki; A G Logan
Abnormalities in the renal and vascular responses to LBNP in humans with early diabetes.
The American journal of physiology 1994;266(2 Pt 2):R442-50.
1993: John S Floras
Clinical aspects of sympathetic activation and parasympathetic withdrawal in heart failure.
Journal of the American College of Cardiology 1993;22(4 Suppl A):72A-84A.
1993: John S Floras; K Hara
Sympathoneural and haemodynamic characteristics of young subjects with mild essential hypertension.
Journal of hypertension 1993;11(6):647-55.
1993: J L Reading; Jack M Goodman; Michael Plyley; John S Floras; P P Liu; Peter R McLaughlin; Roy J Shephard
Vascular conductance and aerobic power in sedentary and active subjects and heart failure patients.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(2):567-73.
1992: K Hara; John S Floras
Effects of naloxone on hemodynamics and sympathetic activity after exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(5):2028-35.
1992: John S Floras
Epinephrine and the genesis of hypertension.
Hypertension 1992;19(1):1-18.
1991: G A Morali; John S Floras; L Legault; S Tobe; K L Skorecki; L M Blendis
Muscle sympathetic nerve activity and renal responsiveness to atrial natriuretic factor during the development of hepatic ascites.
The American journal of medicine 1991;91(4):383-92.
1991: John S Floras
Effect of intermediate-dose naloxone on cardiovascular and sympathoneural adjustments to exercise.
Clinical and investigative medicine. Médecine clinique et experimentale 1991;14(5):409-18.
1991: John S Floras; B L Senn
Absence of post exercise hypotension and sympathoinhibition in normal subjects: additional evidence for increased sympathetic outflow in borderline hypertension.
The Canadian journal of cardiology 1991;7(6):253-8.
1991: John S Floras
Will knowing the variability of ambulatory blood pressure improve clinical outcome? An additional consideration in the critical evaluation of this technology.
Clinical and investigative medicine. Médecine clinique et experimentale 1991;14(3):231-40.
1991: John S Floras; L Legault; G A Morali; K Hara; L M Blendis
Increased sympathetic outflow in cirrhosis and ascites: direct evidence from intraneural recordings.
Annals of internal medicine 1991;114(5):373-80.
1991: Judith A Miller; John S Floras; K L Skorecki; L M Blendis; A G Logan
Renal and humoral responses to sustained cardiopulmonary baroreceptor deactivation in humans.
The American journal of physiology 1991;260(3 Pt 2):R642-8.
1990: John S Floras
Sympathoinhibitory effects of atrial natriuretic factor in normal humans.
Circulation 1990;81(6):1860-73.
1990: John S Floras; M J Sole; B L Morris
Desipramine blocks augmented neurogenic vasoconstrictor responses to epinephrine.
Hypertension 1990;15(2):132-9.