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Alexander Florence

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Objects

Microspheres

Concepts & Ideas

Devices

Drug Delivery Systems

Physiology

Intestinal Absorption

Living Beings

Rats
Mice

Occupations

Procedures

Oral Administration

Phenomena

Physicochemical Phenomena

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Co-Publications
Name
16
Sakthivel, Thiagarajan
10
Uchegbu, Ijeoma
7
Murdan, Sudaxshina
6
Hussain, Nasir
6
Toth, Istvan
6
Turton, John
5
Wilderspin, Andrew
5
Gregoriadis, Gregory
5
Al-Jamal, Khuloud
5
Arunothayanun, P
4
Nasseri, Behrooz
4
Ramaswamy, Chandrasekaran
4
Cummings, Jeff
3
Singh, Baljit
3
Ruenraroengsak, Pakatip

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Publications

TOP 3
Jaitely Vikas; Karatas Aysegül; Florence Alexander T
Water-immiscible room temperature ionic liquids (RTILs) as drug reservoirs for controlled release.
Mizuuchi H; Jaitely V; Murdan S; Florence A T
Room temperature ionic liquids and their mixtures: potential pharmaceutical solvents.
Ribeiro Suzie; Rijpkema Sjoerd G; Durrani Zarmina; Florence Alexander T
PLGA-dendron nanoparticles enhance immunogenicity but not lethal antibody production of a DNA vaccine against anthrax in mice.

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All Publications

2008: Jaitely Vikas; Karatas Aysegül; Florence Alexander T
Water-immiscible room temperature ionic liquids (RTILs) as drug reservoirs for controlled release.
International journal of pharmaceutics 2008;354(1-2):168-73.
2008: Mizuuchi H; Jaitely V; Murdan S; Florence A T
Room temperature ionic liquids and their mixtures: potential pharmaceutical solvents.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;33(4-5):326-31.
2007: Ribeiro Suzie; Rijpkema Sjoerd G; Durrani Zarmina; Florence Alexander T
PLGA-dendron nanoparticles enhance immunogenicity but not lethal antibody production of a DNA vaccine against anthrax in mice.
International journal of pharmaceutics 2007;331(2):228-32.
2007: Suitthimeathegorn Orawan; Turton John A; Mizuuchi Hiroshi; Florence Alexander T
Intramuscular absorption and biodistribution of dexamethasone from non-aqueous emulsions in the rat.
International journal of pharmaceutics 2007;331(2):204-10.
2007: Ruenraroengsak Pakatip; Al-Jamal Khuloud T; Hartell Nicholas; Braeckmans Kevin; De Smedt Stefaan C; Florence Alexander T
Cell uptake, cytoplasmic diffusion and nuclear access of a 6.5 nm diameter dendrimer.
International journal of pharmaceutics 2007;331(2):215-9.
2006: Al-Jamal Khuloud T; Ruenraroengsak Pakatip; Hartell Nicholas; Florence Alexander T
An intrinsically fluorescent dendrimer as a nanoprobe of cell transport.
Journal of drug targeting 2006;14(6):405-12.
2006: Bayele Henry K; Ramaswamy Chandrasekaran; Wilderspin Andrew F; Srai Kaila S; Toth Istvan; Florence Alexander T
Protein transduction by lipidic peptide dendrimers.
Journal of pharmaceutical sciences 2006;95(6):1227-37.
2005: Al-Jamal Khuloud T; Ramaswamy Chandrasekaran; Florence Alexander T
Supramolecular structures from dendrons and dendrimers.
Advanced drug delivery reviews 2005;57(15):2238-70.
2005: Nasseri Behrooz; Florence Alexander T
The relative flow of the walls of phospholipid tether bilayers.
International journal of pharmaceutics 2005;298(2):372-7.
2005: Ribeiro Suzie; Hussain Nasir; Florence Alexander T
Release of DNA from dendriplexes encapsulated in PLGA nanoparticles.
International journal of pharmaceutics 2005;298(2):354-60.
2005: Suitthimeathegorn Orawan; Jaitely Vikas; Florence Alexander T
Novel anhydrous emulsions: formulation as controlled release vehicles.
International journal of pharmaceutics 2005;298(2):367-71.
2005: Ruenraroengsak Pakatip; Florence Alexander T
The diffusion of latex nanospheres and the effective (microscopic) viscosity of HPMC gels.
International journal of pharmaceutics 2005;298(2):361-6.
2005: Singh Baljit; Florence Alexander T
Hydrophobic dendrimer-derived nanoparticles.
International journal of pharmaceutics 2005;298(2):348-53.
2005: Bayele Henry K; Sakthivel T; O'Donell Martin; Pasi K John; Wilderspin Andrew F; Lee Christine A; Toth Istvan; Florence Alexander T
Versatile peptide dendrimers for nucleic acid delivery.
Journal of pharmaceutical sciences 2005;94(2):446-57.
2005: Al-Jamal Khuloud T; Sakthivel Thiagarajan; Florence Alexander T
Dendrisomes: vesicular structures derived from a cationic lipidic dendron.
Journal of pharmaceutical sciences 2005;94(1):102-13.
2005: Zloh Mire; Ramaswamy Chandrasekaran; Sakthivel Thiagarajan; Wilderspin Andy; Florence Alexander T
Investigation of the association and flexibility of cationic lipidic peptide dendrons by NMR spectroscopy.
Magnetic resonance in chemistry : MRC 2005;43(1):47-52.
2004: Florence Alexander T
Issues in oral nanoparticle drug carrier uptake and targeting.
Journal of drug targeting 2004;12(2):65-70.
2003: Singh Baljit; Hussain Nasir; Sakthivel Thiagarajan; Florence Alexander T
Effect of physiological media on the stability of surface-adsorbed DNA-dendron-gold nanoparticles.
The Journal of pharmacy and pharmacology 2003;55(12):1635-40.
2003: Nasseri Behrooz; Florence Alexander T
Microtubules formed by capillary extrusion and fusion of surfactant vesicles.
International journal of pharmaceutics 2003;266(1-2):91-8.
2003: Nasseri Behrooz; Florence Alexander T
A vesicular shuttle: transport of a vesicle within a flexible microtube.
Journal of controlled release : official journal of the Controlled Release Society 2003;92(3):233-40.
2003: Purohit Gaurang; Sakthivel Thiagarajan; Florence Alexander T
The interaction of cationic dendrons with albumin and their diffusion through cellulose membranes.
International journal of pharmaceutics 2003;254(1):37-41.
2003: Al-Jamal Khuloud T; Sakthivel Thiagarajan; Florence Alexander T
Dendrisomes: cationic lipidic dendron vesicular assemblies.
International journal of pharmaceutics 2003;254(1):33-6.
2003: Hussain Nasir; Singh Baljit; Sakthivel Thiagrajan; Florence Alexander T
Formulation and stability of surface-tethered DNA-gold-dendron nanoparticles.
International journal of pharmaceutics 2003;254(1):27-31.
2003: Sakthivel T; Florence A T
Adsorption of amphipathic dendrons on polystyrene nanoparticles.
International journal of pharmaceutics 2003;254(1):23-6.
2003: Ramaswamy Chandrasekaran; Sakthivel Thiagarajan; Wilderspin Andy F; Florence Alexander T
Dendriplexes and their characterisation.
International journal of pharmaceutics 2003;254(1):17-21.
2003: Nasseri Behrooz; Florence Alexander T
Some properties of extruded non-ionic surfactant micro-tubes.
International journal of pharmaceutics 2003;254(1):11-6.
2002: Jensen Malene; Birch Hansen Pernille; Murdan Sudaxshina; Frokjaer Sven; Florence Alexander T
Loading into and electro-stimulated release of peptides and proteins from chondroitin 4-sulphate hydrogels.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;15(2):139-48.
2001: Florence A T; Hussain N
Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas.
Advanced drug delivery reviews 2001;50 Suppl 1():S69-89.
2001: Hussain N; Jaitley V; Florence A T
Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics.
Advanced drug delivery reviews 2001;50(1-2):107-42.
2001: Purohit G; Sakthivel T; Florence A T
Interaction of cationic partial dendrimers with charged and neutral liposomes.
International journal of pharmaceutics 2001;214(1-2):71-6.
2001: Yanai S; Sakthivel T; Florence A T
Interfacial behaviour and micelle formation of novel amphiphilic sequential lipid-lysine oligomers.
International journal of pharmaceutics 2001;214(1-2):49-53.
2001: Sakthivel T; Jaitely V; Patel N V; Florence A T
Non-aqueous emulsions: hydrocarbon-formamide systems.
International journal of pharmaceutics 2001;214(1-2):43-8.
2001: Dimitrijevic D; Whitton P S; Domin M; Welham K; Florence A T
Increased vigabatrin entry into the brain by polysorbate 80 and sodium caprate.
The Journal of pharmacy and pharmacology 2001;53(2):149-54.
2000: Shah D S; Sakthivel T; Toth I; Florence A T; Wilderspin A F
DNA transfection and transfected cell viability using amphipathic asymmetric dendrimers.
International journal of pharmaceutics 2000;208(1-2):41-8.
2000: Arunothayanun P; Bernard M S; Craig D Q; Uchegbu I F; Florence A T
The effect of processing variables on the physical characteristics of non-ionic surfactant vesicles (niosomes) formed from a hexadecyl diglycerol ether.
International journal of pharmaceutics 2000;201(1):7-14.
2000: Florence A T; Sakthivel T; Toth I
Oral uptake and translocation of a polylysine dendrimer with a lipid surface.
Journal of controlled release : official journal of the Controlled Release Society 2000;65(1-2):253-9.
2000: Dimitrijevic D; Shaw A J; Florence A T
Effects of some non-ionic surfactants on transepithelial permeability in Caco-2 cells.
The Journal of pharmacy and pharmacology 2000;52(2):157-62.
1999: Arunothayanun P; Sooksawate T; Florence A T
Extrusion of niosomes from capillaries: approaches to a pulsed delivery device.
Journal of controlled release : official journal of the Controlled Release Society 1999;60(2-3):391-7.
1999: Murdan S; Gregoriadis G; Florence A T
Sorbitan monostearate/polysorbate 20 organogels containing niosomes: a delivery vehicle for antigens?
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1999;8(3):177-86.
1999: Arunothayanun P; Uchegbu I F; Florence A T
Osmotic behaviour of polyhedral non-ionic surfactant vesicles (niosomes).
The Journal of pharmacy and pharmacology 1999;51(6):651-7.
1999: Arunothayanun P; Uchegbu I F; Craig D Q; Turton J A; Florence A T
In vitro/in vivo characterisation of polyhedral niosomes.
International journal of pharmaceutics 1999;183(1):57-61.
1999: Sakthivel T; Toth I; Florence A T
Distribution of a lipidic 2.5 nm diameter dendrimer carrier after oral administration.
International journal of pharmaceutics 1999;183(1):51-5.
1999: Murdan S; Gregoriadis G; Florence A T
Inverse toroidal vesicles: precursors of tubules in sorbitan monostearate organogels.
International journal of pharmaceutics 1999;183(1):47-9.
1999: Carreno-Gómez B; Woodley J F; Florence A T
Studies on the uptake of tomato lectin nanoparticles in everted gut sacs.
International journal of pharmaceutics 1999;183(1):7-11.
1999: Ford J; Woolfe J; Florence A T
Nanospheres of cyclosporin A: poor oral absorption in dogs.
International journal of pharmaceutics 1999;183(1):3-6.
1999: Murdan S; van den Bergh B; Gregoriadis G; Florence A T
Water-in-sorbitan monostearate organogels (water-in-oil gels).
Journal of pharmaceutical sciences 1999;88(6):615-9.
1999: Murdan S; Gregoriadis G; Florence A T
Novel sorbitan monostearate organogels.
Journal of pharmaceutical sciences 1999;88(6):608-14.
1999: Murdan S; Gregoriadis G; Florence A T
Interaction of a nonionic surfactant-based organogel with aqueous media.
International journal of pharmaceutics 1999;180(2):211-4.
1999: Arunothayanun P; Turton J A; Uchegbu I F; Florence A T
Preparation and in vitro/in vivo evaluation of luteinizing hormone releasing hormone (LHRH)-loaded polyhedral and spherical/tubular niosomes.
Journal of pharmaceutical sciences 1999;88(1):34-8.
1998: Sakthivel T; Toth I; Florence A T
Synthesis and physicochemical properties of lipophilic polyamide dendrimers.
Pharmaceutical research 1998;15(5):776-82.
1998: Hussain N; Florence A T
Utilizing bacterial mechanisms of epithelial cell entry: invasin-induced oral uptake of latex nanoparticles.
Pharmaceutical research 1998;15(1):153-6.
1997: Dimitrijevic D; Lamandin C; Uchegbu I F; Shaw A J; Florence A T
The effect of monomers and of micellar and vesicular forms of non-ionic surfactants (Solulan C24 and Solulan 16) on Caco-2 cell monolayers.
The Journal of pharmacy and pharmacology 1997;49(6):611-6.
1997: Uchegbu I F; Schätzlein A; Vanlerberghe G; Morgatini N; Florence A T
Polyhedral non-ionic surfactant vesicles.
The Journal of pharmacy and pharmacology 1997;49(6):606-10.
1997: Florence A T
Peter Howard Elworthy (1933-1995): a biographical note.
The Journal of pharmacy and pharmacology 1997;49(6):579-86.
1997: Hussain N; Jani P U; Florence A T
Enhanced oral uptake of tomato lectin-conjugated nanoparticles in the rat.
Pharmaceutical research 1997;14(5):613-8.
1997: Florence A T
The oral absorption of micro- and nanoparticulates: neither exceptional nor unusual.
Pharmaceutical research 1997;14(3):259-66.
1996: Uchegbu I F; Florence A T
Adverse drug events related to dosage forms and delivery systems.
Drug safety : an international journal of medical toxicology and drug experience 1996;14(1):39-67.
1996: Jani P U; Nomura T; Yamashita F; Takakura Y; Florence A T; Hashida M
Biliary excretion of polystyrene microspheres with covalently linked FITC fluorescence after oral and parenteral administration to male Wistar rats.
Journal of drug targeting 1996;4(2):87-93.
1996: Uchegbu I F; Double J A; Kelland L R; Turton J A; Florence A T
The activity of doxorubicin niosomes against an ovarian cancer cell line and three in vivo mouse tumour models.
Journal of drug targeting 1996;3(5):399-409.
1995: Uchegbu I F; Double J A; Turton J A; Florence A T
Distribution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monostearate (Span 60) niosomes in the mouse.
Pharmaceutical research 1995;12(7):1019-24.
1995: Florence A T; Hillery A M; Hussain N; Jani P U
Factors affecting the oral uptake and translocation of polystyrene nanoparticles: histological and analytical evidence.
Journal of drug targeting 1995;3(1):65-70.
1994: Uchegbu I F; Turton J A; Double J A; Florence A T
Drug distribution and a pulmonary adverse effect of intraperitoneally administered doxorubicin niosomes in the mouse.
Biopharmaceutics & drug disposition 1994;15(8):691-707.
1994: Florence A T; Jani P U
Novel oral drug formulations. Their potential in modulating adverse effects.
Drug safety : an international journal of medical toxicology and drug experience 1994;10(3):233-66.
1994: Hillery A M; Jani P U; Florence A T
Comparative, quantitative study of lymphoid and non-lymphoid uptake of 60 nm polystyrene particles.
Journal of drug targeting 1994;2(2):151-6.
1991: Florence A T; Halbert G W
Lipoproteins and microemulsions as carriers of therapeutic and chemical agents.
Targeted diagnosis and therapy 1991;5():141-74.
1990: Jani P; Halbert G W; Langridge J; Florence A T
Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency.
The Journal of pharmacy and pharmacology 1990;42(12):821-6.
1989: Jani P; Halbert G W; Langridge J; Florence A T
The uptake and translocation of latex nanospheres and microspheres after oral administration to rats.
The Journal of pharmacy and pharmacology 1989;41(12):809-12.
1989: Eley J G; Halbert G W; Florence A T
Incorporation of dyes into low density lipoprotein in the presence of non-ionic surfactants.
The Journal of pharmacy and pharmacology 1989;41(12):858-60.
1989: Darwish I A; Florence A T; Saleh A M
Effects of hydrotropic agents on the solubility, precipitation, and protein binding of etoposide.
Journal of pharmaceutical sciences 1989;78(7):577-81.
1989: Willmott N; Chen Y; Goldberg J; Mcardle C; Florence A T
Biodegradation rate of embolized protein microspheres in lung, liver and kidney of rats.
The Journal of pharmacy and pharmacology 1989;41(7):433-8.
1989: Omotosho J A; Whateley T L; Florence A T
Release of 5-fluorouracil from intramuscular w/o/w multiple emulsions.
Biopharmaceutics & drug disposition 1989;10(3):257-68.
1989: Saleh A M; Florence A T; Whateley T L; el-Khordagui L K
The effect of hydrotropic agents on the heat coagulation of bovine serum albumin.
The Journal of pharmacy and pharmacology 1989;41(5):298-301.
1989: Omotosho J A; Whateley T L; Florence A T
Methotrexate transport from the internal phase of multiple w/o/w emulsions.
Journal of microencapsulation 1989;6(2):183-92.
1989: Halbert G W; Florence A T
Physiochemical characterization of methotrexate-bovine serum albumin conjugates.
The Journal of pharmacy and pharmacology 1989;41(4):222-6.
1989: Cook J M; Florence A T; Russell J; Wheldon T E
Etoposide (VP-16) uptake by tumour spheroids and activity in the presence of Brij 30, formulation additives and sodium salicylate.
European journal of cancer & clinical oncology 1989;25(2):311-8.
1988: Kerr D J; Rogerson A; Morrison G J; Florence A T; Kaye S B
Antitumour activity and pharmacokinetics of niosome encapsulated adriamycin in monolayer, spheroid and xenograft.
British journal of cancer 1988;58(4):432-6.
1988: Rogerson A; Cummings J; Willmott N; Florence A T
The distribution of doxorubicin in mice following administration in niosomes.
The Journal of pharmacy and pharmacology 1988;40(5):337-42.
1987: Chen Y; Willmott N; Anderson J; Florence A T
Comparison of albumin and casein microspheres as a carrier for doxorubicin.
The Journal of pharmacy and pharmacology 1987;39(12):978-85.
1987: Halbert G W; Florence A T; Stuart J F
Characterization of in-vitro drug release and biological activity of methotrexate-bovine serum albumin conjugates.
The Journal of pharmacy and pharmacology 1987;39(11):871-6.
1987: Rogerson A; Cummings J; Florence A T
Adriamycin-loaded niosomes: drug entrapment, stability and release.
Journal of microencapsulation 1987;4(4):321-8.
1987: Kerr D J; Wheldon T E; Russell J G; Maurer H R; Florence A T; Halbert G W; Freshney R I; Kaye S B
The effect of the non-ionic surfactant Brij 30 on the cytotoxicity of adriamycin in monolayer, spheroid and clonogenic culture systems.
European journal of cancer & clinical oncology 1987;23(9):1315-22.
1986: Omotosho J A; Whateley T L; Law T K; Florence A T
The nature of the oil phase and the release of solutes from multiple (w/o/w) emulsions.
The Journal of pharmacy and pharmacology 1986;38(12):865-70.
1986: Mendelow A Y; Forsyth A; Feather J W; Baillie A J; Florence A T
Skin reflectance measurements of patch test responses.
Contact dermatitis 1986;15(2):73-8.
1986: Azmin M N; Florence A T; Handjani-Vila R M; Stuart J F; Vanlerberghe G; Whittaker J S
The effect of niosomes and polysorbate 80 on the metabolism and excretion of methotrexate in the mouse.
Journal of microencapsulation 1986;3(2):95-100.
1985: Baillie A J; Florence A T; Hume L R; Muirhead G T; Rogerson A
The preparation and properties of niosomes--non-ionic surfactant vesicles.
The Journal of pharmacy and pharmacology 1985;37(12):863-8.
1985: Eccleston G M; Florence A T
Application of emulsion theory to complex and real systems.
International journal of cosmetic science 1985;7(5):195-212.
1985: Willmott N; Cummings J; Florence A T
In vitro release of adriamycin from drug-loaded albumin and haemoglobin microspheres.
Journal of microencapsulation 1985;2(4):293-304.
1985: Mendelow A Y; Forsyth A; Florence A T; Baillie A J
Patch testing for nickel allergy. The influence of the vehicle on the response rate to topical nickel sulphate.
Contact dermatitis 1985;13(1):29-33.
1985: Azmin M N; Florence A T; Handjani-Vila R M; Stuart J F; Vanlerberghe G; Whittaker J S
The effect of non-ionic surfactant vesicle (niosome) entrapment on the absorption and distribution of methotrexate in mice.
The Journal of pharmacy and pharmacology 1985;37(4):237-42.
1985: Willmott N; Cummings J; Stuart J F; Florence A T
Adriamycin-loaded albumin microspheres: preparation, in vivo distribution and release in the rat.
Biopharmaceutics & drug disposition 1985;6(1):91-104.
1985: Halbert G W; Stuart J F; Florence A T
A low density lipoprotein-methotrexate covalent complex and its activity against L1210 cells in vitro.
Cancer chemotherapy and pharmacology 1985;15(3):223-7.
1985: Azmin M N; Stuart J F; Florence A T
The distribution and elimination of methotrexate in mouse blood and brain after concurrent administration of polysorbate 80.
Cancer chemotherapy and pharmacology 1985;14(3):238-42.
1982: Azmin M N; Stuart J F; Calman K C; Florence A T
Effects of polysorbate 80 on the absorption and distribution of oral methotrexate (MTX) in mice.
Cancer chemotherapy and pharmacology 1982;9(3):161-4.

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