Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Terence Flotte

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Chemicals & Drugs

Procedures

Disorders

Devices

Gene Transfer Techniques

Physiology

Anatomy

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Stalvey Michael S; Flotte Terence R
Endocrine parameters of cystic fibrosis: Back to basics.
Brantly Mark L; Chulay Jeffrey D; Wang Lili; Mueller Christian; Humphries Margaret; Spencer L Terry; Rouhani Farshid; Conlon Thomas J; Calcedo Roberto; Betts Michael R; Spencer Carolyn; Byrne Barry J; Wilson James M; Flotte Terence R
Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy.
Yu Hong; Zeidan Youssef H; Wu Bill X; Jenkins Russell W; Flotte Terence R; Hannun Yusuf A; Virella-Lowell Isabel
Defective acid sphingomyelinase pathway with Pseudomonas aeruginosa infection in cystic fibrosis.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Terence Flotte (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Stalvey Michael S; Flotte Terence R
Endocrine parameters of cystic fibrosis: Back to basics.
Journal of cellular biochemistry 2009;108(2):353-61.
2009: Brantly Mark L; Chulay Jeffrey D; Wang Lili; Mueller Christian; Humphries Margaret; Spencer L Terry; Rouhani Farshid; Conlon Thomas J; Calcedo Roberto; Betts Michael R; Spencer Carolyn; Byrne Barry J; Wilson James M; Flotte Terence R
Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16363-8.
2009: Yu Hong; Zeidan Youssef H; Wu Bill X; Jenkins Russell W; Flotte Terence R; Hannun Yusuf A; Virella-Lowell Isabel
Defective acid sphingomyelinase pathway with Pseudomonas aeruginosa infection in cystic fibrosis.
American journal of respiratory cell and molecular biology 2009;41(3):367-75.
2009: Pashuck Troy D; Franz Sarah E; Altman Molly K; Wasserfall Clive H; Atkinson Mark A; Wronski Thomas J; Flotte Terence R; Stalvey Michael S
Murine model for cystic fibrosis bone disease demonstrates osteopenia and sex-related differences in bone formation.
Pediatric research 2009;65(3):311-6.
2009: Mueller C; Braag S A; Martino A T; Tang Q; Campbell-Thompson M; Flotte T R
The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr-/- -dependent allergy mouse model.
Gene therapy 2009;16(2):172-83.
2009: Liqun Wang Rejean; McLaughlin Thomas; Cossette Travis; Tang Qiushi; Foust Kevin; Campbell-Thompson Martha; Martino Ashley; Cruz Pedro; Loiler Scott; Mueller Christian; Flotte Terence R
Recombinant AAV serotype and capsid mutant comparison for pulmonary gene transfer of alpha-1-antitrypsin using invasive and noninvasive delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(1):81-7.
2008: Mueller Christian; Flotte Terence R
Gene therapy for cystic fibrosis.
Clinical reviews in allergy & immunology 2008;35(3):164-78.
2008: Stalvey Michael S; Brusko Todd M; Mueller Christian; Wasserfall Clive H; Schatz Desmond A; Atkinson Mark A; Flotte Terence R
CFTR mutations impart elevated immune reactivity in a murine model of cystic fibrosis related diabetes.
Cytokine 2008;44(1):154-9.
2008: Hauswirth William W; Aleman Tomas S; Kaushal Shalesh; Cideciyan Artur V; Schwartz Sharon B; Wang Lili; Conlon Thomas J; Boye Sanford L; Flotte Terence R; Byrne Barry J; Jacobson Samuel G
Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial.
Human gene therapy 2008;19(10):979-90.
2008: Beattie Stuart G; Goetzman Eric; Tang Qiuishi; Conlon Thomas; Campbell-Thompson Martha; Matern Dietrich; Vockley Jerry; Flotte Terence R
Recombinant adeno-associated virus-mediated gene delivery of long chain acyl coenzyme A dehydrogenase (LCAD) into LCAD-deficient mice.
The journal of gene medicine 2008;10(10):1113-23.
2008: Cideciyan Artur V; Aleman Tomas S; Boye Sanford L; Schwartz Sharon B; Kaushal Shalesh; Roman Alejandro J; Pang Ji-Jing; Sumaroka Alexander; Windsor Elizabeth A M; Wilson James M; Flotte Terence R; Fishman Gerald A; Heon Elise; Stone Edwin M; Byrne Barry J; Jacobson Samuel G; Hauswirth William W
Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):15112-7.
2008: Silver Jared N; Flotte Terence R
Towards a rAAV-based gene therapy for ADA-SCID: from ADA deficiency to current and future treatment strategies.
Pharmacogenomics 2008;9(7):947-68.
2008: Flotte Terence R; Goetzmann Jason; Caridi James; Paolillo Joseph; Conlon Thomas J; Potter Mark; Mueller Christian; Byrne Barry J
Apparently nonspecific enzyme elevations after portal vein delivery of recombinant adeno-associated virus serotype 2 vector in hepatitis C virus-infected chimpanzees.
Human gene therapy 2008;19(7):681-9.
2008: Beattie Stuart G; Goetzman Eric; Conlon Thomas; Germain Sean; Walter Glenn; Campbell-Thompson Martha; Matern Dietrich; Vockley Jerry; Flotte Terence R
Biochemical correction of short-chain acyl-coenzyme A dehydrogenase deficiency after portal vein injection of rAAV8-SCAD.
Human gene therapy 2008;19(6):579-88.
2008: Mueller C; Flotte T R
Clinical gene therapy using recombinant adeno-associated virus vectors.
Gene therapy 2008;15(11):858-63.
2008: Flotte Terence R
In utero efficacy of cystic fibrosis gene therapy: difficult studies, positive or negative.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(5):806-7.
2008: Foust Kevin D; Flotte Terence R; Reier Paul J; Mandel Ronald J
Recombinant adeno-associated virus-mediated global anterograde delivery of glial cell line-derived neurotrophic factor to the spinal cord: comparison of rubrospinal and corticospinal tracts in the rat.
Human gene therapy 2008;19(1):71-82.
2008: Foust Kevin D; Poirier Amy; Pacak Christina A; Mandel Ronald J; Flotte Terence R
Neonatal intraperitoneal or intravenous injections of recombinant adeno-associated virus type 8 transduce dorsal root ganglia and lower motor neurons.
Human gene therapy 2008;19(1):61-70.
2008: Mueller Christian; Torrez Daniel; Braag Sofia; Martino Ashley; Clarke Tracy; Campbell-Thompson Martha; Flotte Terence R
Partial correction of the CFTR-dependent ABPA mouse model with recombinant adeno-associated virus gene transfer of truncated CFTR gene.
The journal of gene medicine 2008;10(1):51-60.
2007: Flotte Terence R
Gene therapy: the first two decades and the current state-of-the-art.
Journal of cellular physiology 2007;213(2):301-5.
2007: Cruz Pedro E; Mueller Christian; Flotte Terence R
The promise of gene therapy for the treatment of alpha-1 antitrypsin deficiency.
Pharmacogenomics 2007;8(9):1191-8.
2007: Cruz Pedro E; Mueller Christian; Cossette Travis L; Golant Alexandra; Tang Qiushi; Beattie Stuart G; Brantly Mark; Campbell-Thompson Martha; Blomenkamp Keith S; Teckman Jeffrey H; Flotte Terence R
In vivo post-transcriptional gene silencing of alpha-1 antitrypsin by adeno-associated virus vectors expressing siRNA.
Laboratory investigation; a journal of technical methods and pathology 2007;87(9):893-902.
2007: Erger Kirsten E; Conlon Thomas J; Leal Nicole A; Zori Robert; Bobik Thomas A; Flotte Terence R
In vivo expression of human ATP:cob(I)alamin adenosyltransferase (ATR) using recombinant adeno-associated virus (rAAV) serotypes 2 and 8.
The journal of gene medicine 2007;9(6):462-9.
2007: Chen B; Kapturczak M H; Joseph R; George J F; Campbell-Thompson M; Wasserfall C H; Atkinson M A; Tisher C C; Flotte T R; Agarwal A; Chen S
Adeno-associated viral vector-mediated interleukin-10 prolongs allograft survival in a rat kidney transplantation model.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(5):1112-20.
2007: Flotte Terence R; Conlon Thomas J; Poirier Amy; Campbell-Thompson Martha; Byrne Barry J
Preclinical characterization of a recombinant adeno-associated virus type 1-pseudotyped vector demonstrates dose-dependent injection site inflammation and dissemination of vector genomes to distant sites.
Human gene therapy 2007;18(3):245-56.
2007: Flotte Terence R; Ng Philip; Dylla Doug E; McCray Paul B; Wang Guoshun; Kolls Jay K; Hu Jim
Viral vector-mediated and cell-based therapies for treatment of cystic fibrosis.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(2):229-41.
2006: Brantly Mark L; Spencer L Terry; Humphries Margaret; Conlon Thomas J; Spencer Carolyn T; Poirier Amy; Garlington Wendy; Baker Dawn; Song Sihong; Berns Kenneth I; Muzyczka Nicholas; Snyder Richard O; Byrne Barry J; Flotte Terence R
Phase I trial of intramuscular injection of a recombinant adeno-associated virus serotype 2 alphal-antitrypsin (AAT) vector in AAT-deficient adults.
Human gene therapy 2006;17(12):1177-86.
2006: Milligan Erin D; Sloane Evan M; Langer Stephen J; Hughes Travis S; Jekich Brian M; Frank Matthew G; Mahoney John H; Levkoff Lindsay H; Maier Steven F; Cruz Pedro E; Flotte Terence R; Johnson Kirk W; Mahoney Melissa M; Chavez Raymond A; Leinwand Leslie A; Watkins Linda R
Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain.
Pain 2006;126(1-3):294-308.
2006: Blenman Kim R M; Duan Byian; Xu Zhiwei; Wan Suigui; Atkinson Mark A; Flotte Terence R; Croker Byron P; Morel Laurence
IL-10 regulation of lupus in the NZM2410 murine model.
Laboratory investigation; a journal of technical methods and pathology 2006;86(11):1136-48.
2006: Petrache Irina; Fijalkowska Iwona; Medler Terry R; Skirball Jarrett; Cruz Pedro; Zhen Lijie; Petrache Horia I; Flotte Terence R; Tuder Rubin M
alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis.
The American journal of pathology 2006;169(4):1155-66.
2006: Flotte Terence R; Frentzen Barbara; Humphries Margaret R; Rosenbloom Arlan L
Recent developments in the protection of pediatric research subjects.
The Journal of pediatrics 2006;149(3):285-286.
2006: Jacobson Samuel G; Boye Sanford L; Aleman Tomas S; Conlon Thomas J; Zeiss Caroline J; Roman Alejandro J; Cideciyan Artur V; Schwartz Sharon B; Komaromy Andras M; Doobrajh Michelle; Cheung Andy Y; Sumaroka Alexander; Pearce-Kelling Susan E; Aguirre Gustavo D; Kaushal Shalesh; Maguire Albert M; Flotte Terence R; Hauswirth William W
Safety in nonhuman primates of ocular AAV2-RPE65, a candidate treatment for blindness in Leber congenital amaurosis.
Human gene therapy 2006;17(8):845-58.
2006: Stalvey Michael S; Muller Christian; Schatz Desmond A; Wasserfall Clive H; Campbell-Thompson Martha L; Theriaque Douglas W; Flotte Terence R; Atkinson Mark A
Cystic fibrosis transmembrane conductance regulator deficiency exacerbates islet cell dysfunction after beta-cell injury.
Diabetes 2006;55(7):1939-45.
2006: Jacobson Samuel G; Acland Gregory M; Aguirre Gustavo D; Aleman Tomas S; Schwartz Sharon B; Cideciyan Artur V; Zeiss Caroline J; Komaromy Andras M; Kaushal Shalesh; Roman Alejandro J; Windsor Elizabeth A M; Sumaroka Alexander; Pearce-Kelling Susan E; Conlon Thomas J; Chiodo Vincent A; Boye Sanford L; Flotte Terence R; Maguire Albert M; Bennett Jean; Hauswirth William W
Safety of recombinant adeno-associated virus type 2-RPE65 vector delivered by ocular subretinal injection.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(6):1074-84.
2006: Lu Yuanqing; Choi Young-Kook; Campbell-Thompson Martha; Li Chengwen; Tang Qiushi; Crawford James M; Flotte Terence R; Song Sihong
Therapeutic level of functional human alpha 1 antitrypsin (hAAT) secreted from murine muscle transduced by adeno-associated virus (rAAV1) vector.
The journal of gene medicine 2006;8(6):730-5.
2006: Seo Byoung Boo; Nakamaru-Ogiso Eiko; Flotte Terence R; Matsuno-Yagi Akemi; Yagi Takao
In vivo complementation of complex I by the yeast Ndi1 enzyme. Possible application for treatment of Parkinson disease.
The Journal of biological chemistry 2006;281(20):14250-5.
2006: Müller Christian; Braag Sofia A; Herlihy John-David; Wasserfall Clive H; Chesrown Sarah E; Nick Harry S; Atkinson Mark A; Flotte Terence R
Enhanced IgE allergic response to Aspergillus fumigatus in CFTR-/- mice.
Laboratory investigation; a journal of technical methods and pathology 2006;86(2):130-40.
2006: Kaplan Karly A; Beierle Elizabeth A; Faro Albert; Eskin Thomas A; Flotte Terence R
Recurrent pneumonia in children: a case report and approach to diagnosis.
Clinical pediatrics 2006;45(1):15-22.
2006: Conlon Thomas J; Walter Glenn; Owen Renius; Cossette Travis; Erger Kirsten; Gutierrez Greg; Goetzman Eric; Matern Dietrich; Vockley Jerry; Flotte Terence R
Systemic correction of a fatty acid oxidation defect by intramuscular injection of a recombinant adeno-associated virus vector.
Human gene therapy 2006;17(1):71-80.
2005: Flotte Terence R
Adeno-associated virus-based gene therapy for inherited disorders.
Pediatric research 2005;58(6):1143-7.
2005: Mu Wei; Ouyang Xiaosen; Agarwal Anupam; Zhang Li; Long David A; Cruz Pedro E; Roncal Carlos A; Glushakova Olena Y; Chiodo Vince A; Atkinson Mark A; Hauswirth William W; Flotte Terry R; Rodriguez-Iturbe Bernardo; Johnson Richard J
IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease.
Journal of the American Society of Nephrology : JASN 2005;16(12):3651-60.
2005: Swiatecka-Urban Agnieszka; Brown Andrea; Moreau-Marquis Sophie; Renuka Janhavi; Coutermarsh Bonita; Barnaby Roxanna; Karlson Katherine H; Flotte Terence R; Fukuda Mitsunori; Langford George M; Stanton Bruce A
The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells.
The Journal of biological chemistry 2005;280(44):36762-72.
2005: Conlon Thomas J; Cossette Travis; Erger Kirsten; Choi Young-Kook; Clarke Tracy; Scott-Jorgensen Marda; Song Sihong; Campbell-Thompson Martha; Crawford James; Flotte Terence R
Efficient hepatic delivery and expression from a recombinant adeno-associated virus 8 pseudotyped alpha1-antitrypsin vector.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(5):867-75.
2005: Loiler Scott A; Tang Qiushi; Clarke Tracy; Campbell-Thompson Martha L; Chiodo Vince; Hauswirth William; Cruz Pedro; Perret-Gentil Marcel; Atkinson Mark A; Ramiya Vijayakumar K; Flotte Terence R
Localized gene expression following administration of adeno-associated viral vectors via pancreatic ducts.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(3):519-27.
2005: Flotte Terence R; Schwiebert Erik M; Zeitlin Pamela L; Carter Barrie J; Guggino William B
Correlation between DNA transfer and cystic fibrosis airway epithelial cell correction after recombinant adeno-associated virus serotype 2 gene therapy.
Human gene therapy 2005;16(8):921-8.
2005: Virella-Lowell Isabel; Zusman Benjamin; Foust Kevin; Loiler Scott; Conlon Thomas; Song Sihong; Chesnut Kye A; Ferkol Thomas; Flotte Terence R
Enhancing rAAV vector expression in the lung.
The journal of gene medicine 2005;7(7):842-50.
2005: Flotte Terence R
Recent developments in recombinant AAV-mediated gene therapy for lung diseases.
Current gene therapy 2005;5(3):361-6.
2005: Flotte Terence R
Adeno-associated virus-mediated gene transfer for lung diseases.
Human gene therapy 2005;16(6):643-8.
2005: Chen Sifeng; Kapturczak Matthias H; Wasserfall Clive; Glushakova Olena Y; Campbell-Thompson Martha; Deshane Jessy S; Joseph Reny; Cruz Pedro E; Hauswirth William W; Madsen Kirsten M; Croker Byron P; Berns Kenneth I; Atkinson Mark A; Flotte Terence R; Tisher C Craig; Agarwal Anupam
Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(20):7251-6.
2005: Flotte Terence R; Berns Kenneth I
Adeno-associated virus: a ubiquitous commensal of mammals.
Human gene therapy 2005;16(4):401-7.
2005: Chen Sifeng; Kapturczak Matthias; Loiler Scott A; Zolotukhin Sergei; Glushakova Olena Y; Madsen Kirsten M; Samulski Richard J; Hauswirth William W; Campbell-Thompson Martha; Berns Kenneth I; Flotte Terence R; Atkinson Mark A; Tisher C Craig; Agarwal Anupam
Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors.
Human gene therapy 2005;16(2):235-47.
2005: Mohiuddin Imran; Loiler Scott; Zolotukhin Irina; Byrne Barry J; Flotte Terence R; Snyder Richard O
Herpesvirus-based infectious titering of recombinant adeno-associated viral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(2):320-6.
2005: Milligan Erin D; Sloane Evan M; Langer Stephen J; Cruz Pedro E; Chacur Marucia; Spataro Leah; Wieseler-Frank Julie; Hammack Sayamwong E; Maier Steven F; Flotte Terence R; Forsayeth John R; Leinwand Leslie A; Chavez Raymond; Watkins Linda R
Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10.
Molecular pain 2005;1():9.
2004: Song Sihong; Witek Rafal P; Lu Yuanqing; Choi Young-Kook; Zheng Donghang; Jorgensen Marda; Li Chengwen; Flotte Terence R; Petersen Byron E
Ex vivo transduced liver progenitor cells as a platform for gene therapy in mice.
Hepatology (Baltimore, Md.) 2004;40(4):918-24.
2004: Seo Byoung Boo; Nakamaru-Ogiso Eiko; Cruz Pedro; Flotte Terence R; Yagi Takao; Matsuno-Yagi Akemi
Functional expression of the single subunit NADH dehydrogenase in mitochondria in vivo: a potential therapy for complex I deficiencies.
Human gene therapy 2004;15(9):887-95.
2004: Sirninger Jeffrey; Muller Christian; Braag Sofia; Tang Qiushi; Yue Hungwen; Detrisac Carol; Ferkol Thomas; Guggino William B; Flotte Terence R
Functional characterization of a recombinant adeno-associated virus 5-pseudotyped cystic fibrosis transmembrane conductance regulator vector.
Human gene therapy 2004;15(9):832-41.
2004: Virella-Lowell Isabel; Herlihy John-David; Liu Barry; Lopez Cecilia; Cruz Pedro; Muller Chris; Baker Henry V; Flotte Terence R
Effects of CFTR, interleukin-10, and Pseudomonas aeruginosa on gene expression profiles in a CF bronchial epithelial cell Line.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(3):562-73.
2004: Conlon Thomas J; Flotte Terence R
Recombinant adeno-associated virus vectors for gene therapy.
Expert opinion on biological therapy 2004;4(7):1093-101.
2004: Flotte Terence R
Immune responses to recombinant adeno-associated virus vectors: putting preclinical findings into perspective.
Human gene therapy 2004;15(7):716-7.
2004: Flotte T R
Gene therapy progress and prospects: recombinant adeno-associated virus (rAAV) vectors.
Gene therapy 2004;11(10):805-10.
2004: Bray Christopher L; Cahill Kevin S; Oshier Joseph T; Peden Carmen S; Theriaque Douglas W; Flotte Terence R; Stacpoole Peter W
Methylphenidate does not improve cognitive function in healthy sleep-deprived young adults.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2004;52(3):192-201.
2004: Song Sihong; Lu Yuanqing; Choi Young-Kook; Han Yinong; Tang Qiushi; Zhao Ge; Berns Kenneth I; Flotte Terence R
DNA-dependent PK inhibits adeno-associated virus DNA integration.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2112-6.
2004: Flotte Terence R; Brantly Mark L; Spencer L Terry; Byrne Barry J; Spencer Carolyn T; Baker Dawn J; Humphries Margaret
Phase I trial of intramuscular injection of a recombinant adeno-associated virus alpha 1-antitrypsin (rAAV2-CB-hAAT) gene vector to AAT-deficient adults.
Human gene therapy 2004;15(1):93-128.
2004: Song S; Goudy K; Campbell-Thompson M; Wasserfall C; Scott-Jorgensen M; Wang J; Tang Q; Crawford J M; Ellis T M; Atkinson M A; Flotte T R
Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice.
Gene therapy 2004;11(2):181-6.
2003: Fischer Anne C; Beck Suzanne E; Smith Carolina I; Laube Beth L; Askin Frederic B; Guggino Sandra E; Adams Robert J; Flotte Terence R; Guggino William B
Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(6):918-26.
2003: Burkhardt Brant R; Loiler Scott A; Anderson Jo Anne; Kilberg Michael S; Crawford James M; Flotte Terence R; Goudy Kevin S; Ellis Tamir M; Atkinson Mark
Glucose-responsive expression of the human insulin promoter in HepG2 human hepatoma cells.
Annals of the New York Academy of Sciences 2003;1005():237-41.
2003: Goudy Kevin S; Burkhardt Brant R; Wasserfall Clive; Song Sihong; Campbell-Thompson Martha L; Brusko Todd; Powers Matthew A; Clare-Salzler Michael J; Sobel Eric S; Ellis Tamir M; Flotte Terence R; Atkinson Mark A
Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2270-8.
2003: Loiler S A; Conlon T J; Song S; Tang Q; Warrington K H; Agarwal A; Kapturczak M; Li C; Ricordi C; Atkinson M A; Muzyczka N; Flotte T R
Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver.
Gene therapy 2003;10(18):1551-8.
2003: Flotte Terence R; Zeitlin Pamela L; Reynolds Thomas C; Heald Alison E; Pedersen Patty; Beck Suzanne; Conrad Carol K; Brass-Ernst Lois; Humphries Margaret; Sullivan Kevin; Wetzel Randall; Taylor George; Carter Barrie J; Guggino William B
Phase I trial of intranasal and endobronchial administration of a recombinant adeno-associated virus serotype 2 (rAAV2)-CFTR vector in adult cystic fibrosis patients: a two-part clinical study.
Human gene therapy 2003;14(11):1079-88.
2003: Flotte Terence R
The signal and the trap: targeted delivery and retention of proteins in the mitochondrion.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(6):715-6.
2003: Stacpoole Peter W; Owen Renius; Flotte Terence R
The pyruvate dehydrogenase complex as a target for gene therapy.
Current gene therapy 2003;3(3):239-45.
2003: Chen Sifeng; Agarwal Anupam; Glushakova Olena Y; Jorgensen Marda S; Salgar Shashikumar K; Poirier Amy; Flotte Terence R; Croker Byron P; Madsen Kirsten M; Atkinson Mark A; Hauswirth William W; Berns Kenneth I; Tisher C Craig
Gene delivery in renal tubular epithelial cells using recombinant adeno-associated viral vectors.
Journal of the American Society of Nephrology : JASN 2003;14(4):947-58.
2002: Barbour Karen W; Wei FuSheng; Brannan Camilynn; Flotte Terence R; Baumann Heinz; Berger Franklin G
The murine alpha(1)-proteinase inhibitor gene family: polymorphism, chromosomal location, and structure.
Genomics 2002;80(5):515-22.
2002: Snyder Richard O; Flotte Terence R
Production of clinical-grade recombinant adeno-associated virus vectors.
Current opinion in biotechnology 2002;13(5):418-23.
2002: Zolotukhin Sergei; Potter Mark; Zolotukhin Irene; Sakai Yoshihisa; Loiler Scott; Fraites Thomas J; Chiodo Vince A; Phillipsberg Tina; Muzyczka Nicholas; Hauswirth William W; Flotte Terance R; Byrne Barry J; Snyder Richard O
Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors.
Methods (San Diego, Calif.) 2002;28(2):158-67.
2002: Beck Suzanne E; Laube Beth L; Barberena Carolina I; Fischer Anne C; Adams Robert J; Chesnut Kye; Flotte Terence R; Guggino William B
Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus macaques.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(4):546-54.
2002: Owen Renius; Mandel Ronald J; Ammini Chandramohan V; Conlon Thomas J; Kerr Douglas S; Stacpoole Peter W; Flotte Terence R
Gene therapy for pyruvate dehydrogenase E1alpha deficiency using recombinant adeno-associated virus 2 (rAAV2) vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(3):394-9.
2002: Seo Byoung Boo; Nakamaru-Ogiso Eiko; Flotte Terence R; Yagi Takao; Matsuno-Yagi Akemi
A single-subunit NADH-quinone oxidoreductase renders resistance to mammalian nerve cells against complex I inhibition.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(3):336-41.
2002: Song Sihong; Scott-Jorgensen Marda; Wang Jianming; Poirier Amy; Crawford James; Campbell-Thompson Martha; Flotte Terence R
Intramuscular administration of recombinant adeno-associated virus 2 alpha-1 antitrypsin (rAAV-SERPINA1) vectors in a nonhuman primate model: safety and immunologic aspects.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(3):329-35.
2002: Wagner John A; Nepomuceno Ilynn B; Messner Anna H; Moran Mary Lynn; Batson Eric P; Dimiceli Sue; Brown Byron W; Desch Julie K; Norbash Alexander M; Conrad Carol K; Guggino William B; Flotte Terence R; Wine Jeffrey J; Carter Barrie J; Reynolds Thomas C; Moss Richard B; Gardner Phyllis
A phase II, double-blind, randomized, placebo-controlled clinical trial of tgAAVCF using maxillary sinus delivery in patients with cystic fibrosis with antrostomies.
Human gene therapy 2002;13(11):1349-59.
2002: Mah Cathryn; Fraites Thomas J; Zolotukhin Irene; Song Sihong; Flotte Terence R; Dobson Jon; Batich Christopher; Byrne Barry J
Improved method of recombinant AAV2 delivery for systemic targeted gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(1):106-12.
2002: Flotte Terence R
Recombinant adeno-associated virus gene therapy for cystic fibrosis and alpha(1)-antitrypsin deficiency.
Chest 2002;121(3 Suppl):98S-102S.
2002: Kapturczak Matthias; Zolotukhin Sergei; Cross Jeff; Pileggi Antonello; Molano R Damaris; Jorgensen Marda; Byrne Barry; Flotte Terence R; Ellis Tamir; Inverardi Luca; Ricordi Camillo; Nick Harry; Atkinson Mark; Agarwal Anupam
Transduction of human and mouse pancreatic islet cells using a bicistronic recombinant adeno-associated viral vector.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(2):154-60.
2002: Mah Cathryn; Byrne Barry J; Flotte Terence R
Virus-based gene delivery systems.
Clinical pharmacokinetics 2002;41(12):901-11.
2002: Flotte Terence R; Virella-Lowell Isabel; Chesnut Kye A
Adeno-associated viral vectors for CF gene therapy.
Methods in molecular medicine 2002;70():599-608.
2001: Goudy K; Song S; Wasserfall C; Zhang Y C; Kapturczak M; Muir A; Powers M; Scott-Jorgensen M; Campbell-Thompson M; Crawford J M; Ellis T M; Flotte T R; Atkinson M A
Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13913-8.
2001: Flotte T R
Recombinant adeno-associated virus vectors for cystic fibrosis gene therapy.
Current opinion in molecular therapeutics 2001;3(5):497-502.
2001: Song S; Embury J; Laipis P J; Berns K I; Crawford J M; Flotte T R
Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectors.
Gene therapy 2001;8(17):1299-306.
2001: Flotte T R; Laube B L
Gene therapy in cystic fibrosis.
Chest 2001;120(3 Suppl):124S-131S.
2001: Song S; Laipis P J; Berns K I; Flotte T R
Effect of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):4084-8.
2000: Seo B B; Wang J; Flotte T R; Yagi T; Matsuno-Yagi A
Use of the NADH-quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae as a possible cure for complex I defects in human cells.
The Journal of biological chemistry 2000;275(48):37774-8.
2000: Virella-Lowell I; Poirier A; Chesnut K A; Brantly M; Flotte T R
Inhibition of recombinant adeno-associated virus (rAAV) transduction by bronchial secretions from cystic fibrosis patients.
Gene therapy 2000;7(20):1783-9.
2000: Owen R I V; Lewin A P; Peel A; Wang J; Guy J; Hauswirth W W; Stacpoole P W; Flotte T R
Recombinant adeno-associated virus vector-based gene transfer for defects in oxidative metabolism.
Human gene therapy 2000;11(15):2067-78.
2000: Flotte T R
Size does matter: overcoming the adeno-associated virus packaging limit.
Respiratory research 2000;1(1):16-8.
1999: Beck S E; Jones L A; Chesnut K; Walsh S M; Reynolds T C; Carter B J; Askin F B; Flotte T R; Guggino W B
Repeated delivery of adeno-associated virus vectors to the rabbit airway.
Journal of virology 1999;73(11):9446-55.
1999: Hernandez Y J; Wang J; Kearns W G; Loiler S; Poirier A; Flotte T R
Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model.
Journal of virology 1999;73(10):8549-58.
1999: Flotte T R
Gene therapy for cystic fibrosis.
Current opinion in molecular therapeutics 1999;1(4):510-6.
1999: Wagner J A; Messner A H; Moran M L; Daifuku R; Kouyama K; Desch J K; Manley S; Norbash A M; Conrad C K; Friborg S; Reynolds T; Guggino W B; Moss R B; Carter B J; Wine J J; Flotte T R; Gardner P
Safety and biological efficacy of an adeno-associated virus vector-cystic fibrosis transmembrane regulator (AAV-CFTR) in the cystic fibrosis maxillary sinus.
The Laryngoscope 1999;109(2 Pt 1):266-74.
1998: Song S; Morgan M; Ellis T; Poirier A; Chesnut K; Wang J; Brantly M; Muzyczka N; Byrne B J; Atkinson M; Flotte T R
Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14384-8.
1998: Wagner J A; Reynolds T; Moran M L; Moss R B; Wine J J; Flotte T R; Gardner P
Efficient and persistent gene transfer of AAV-CFTR in maxillary sinus.
Lancet 1998;351(9117):1702-3.
1998: Wagner J A; Moran M L; Messner A H; Daifuku R; Conrad C K; Reynolds T; Guggino W B; Moss R B; Carter B J; Wine J J; Flotte T R; Gardner P
A phase I/II study of tgAAV-CF for the treatment of chronic sinusitis in patients with cystic fibrosis.
Human gene therapy 1998;9(6):889-909.
1998: Flotte T R; Beck S E; Chesnut K; Potter M; Poirier A; Zolotukhin S
A fluorescence video-endoscopy technique for detection of gene transfer and expression.
Gene therapy 1998;5(2):166-73.
1998: Flotte T R; Carter B J
Adeno-associated virus vectors for gene therapy of cystic fibrosis.
Methods in enzymology 1998;292():717-32.
1997: Rubenstein R C; McVeigh U; Flotte T R; Guggino W B; Zeitlin P L
CFTR gene transduction in neonatal rabbits using an adeno-associated virus (AAV) vector.
Gene therapy 1997;4(5):384-92.
1997: Flotte T R; Carter B J
In vivo gene therapy with adeno-associated virus vectors for cystic fibrosis.
Advances in pharmacology (San Diego, Calif.) 1997;40():85-101.
1996: Kearns W G; Afione S A; Fulmer S B; Pang M C; Erikson D; Egan M; Landrum M J; Flotte T R; Cutting G R
Recombinant adeno-associated virus (AAV-CFTR) vectors do not integrate in a site-specific fashion in an immortalized epithelial cell line.
Gene therapy 1996;3(9):748-55.
1996: Conrad C K; Allen S S; Afione S A; Reynolds T C; Beck S E; Fee-Maki M; Barrazza-Ortiz X; Adams R; Askin F B; Carter B J; Guggino W B; Flotte T R
Safety of single-dose administration of an adeno-associated virus (AAV)-CFTR vector in the primate lung.
Gene therapy 1996;3(8):658-68.
1996: Baudard M; Flotte T R; Aran J M; Thierry A R; Pastan I; Pang M G; Kearns W G; Gottesman M M
Expression of the human multidrug resistance and glucocerebrosidase cDNAs from adeno-associated vectors: efficient promoter activity of AAV sequences and in vivo delivery via liposomes.
Human gene therapy 1996;7(11):1309-22.
1996: Afione S A; Conrad C K; Kearns W G; Chunduru S; Adams R; Reynolds T C; Guggino W B; Cutting G R; Carter B J; Flotte T R
In vivo model of adeno-associated virus vector persistence and rescue.
Journal of virology 1996;70(5):3235-41.
1995: Zeitlin P L; Chu S; Conrad C; McVeigh U; Ferguson K; Flotte T R; Guggino W B
Alveolar stem cell transduction by an adeno-associated viral vector.
Gene therapy 1995;2(9):623-31.
1995: Flotte T R; Carter B J
Adeno-associated virus vectors for gene therapy.
Gene therapy 1995;2(6):357-62.
1995: Murray C B; Morales M M; Flotte T R; McGrath-Morrow S A; Guggino W B; Zeitlin P L
CIC-2: a developmentally dependent chloride channel expressed in the fetal lung and downregulated after birth.
American journal of respiratory cell and molecular biology 1995;12(6):597-604.
1995: Carroll T P; Morales M M; Fulmer S B; Allen S S; Flotte T R; Cutting G R; Guggino W B
Alternate translation initiation codons can create functional forms of cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry 1995;270(20):11941-6.
1995: Afione S A; Conrad C K; Flotte T R
Gene therapy vectors as drug delivery systems.
Clinical pharmacokinetics 1995;28(3):181-9.
1995: Flotte T R; Barraza-Ortiz X; Solow R; Afione S A; Carter B J; Guggino W B
An improved system for packaging recombinant adeno-associated virus vectors capable of in vivo transduction.
Gene therapy 1995;2(1):29-37.
1994: Flotte T R; Afione S A; Zeitlin P L
Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration.
American journal of respiratory cell and molecular biology 1994;11(5):517-21.
1993: Flotte T R; Afione S A; Conrad C; McGrath S A; Solow R; Oka H; Zeitlin P L; Guggino W B; Carter B J
Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10613-7.
1993: Tomares S M; Flotte T R; Tunkel D E; Pao M; Loughlin G M
Real time laryngoscopy with olfactory challenge for diagnosis of psychogenic stridor.
Pediatric pulmonology 1993;16(4):259-62.
1993: Flotte T R
Prospects for virus-based gene therapy for cystic fibrosis.
Journal of bioenergetics and biomembranes 1993;25(1):37-42.
1993: Flotte T R; Afione S A; Solow R; Drumm M L; Markakis D; Guggino W B; Zeitlin P L; Carter B J
Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter.
The Journal of biological chemistry 1993;268(5):3781-90.
1992: Flotte T R; Solow R; Owens R A; Afione S; Zeitlin P L; Carter B J
Gene expression from adeno-associated virus vectors in airway epithelial cells.
American journal of respiratory cell and molecular biology 1992;7(3):349-56.
1991: Flotte T R; Loughlin G M
Benefits and complications of troleandomycin (TAO) in young children with steroid-dependent asthma.
Pediatric pulmonology 1991;10(3):178-82.
1988: Flotte T R
Dietl syndrome: intermittent ureteropelvic junction obstruction as a cause of episodic abdominal pain.
Pediatrics 1988;82(5):792-4.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Terence Flotte

Research Profile (preview)

Living Beings

Chemicals & Drugs

Procedures

Disorders

Devices

Physiology

Anatomy

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Terence Flotte (preview)

All Publications