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Roderick Flower
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71
Perretti, Mauro
22
Croxtall, Jamie
15
Choudhury, Qamrul
10
Yona, Simon
9
Getting, Stephen
8
Oliani, Sonia
8
Paul-Clark, Mark
8
Solito, Egle
6
Wheller, Samantha
6
Gavins, Felicity
6
Buckingham, Julia
5
Ajuebor, MN
5
Bolton, Christopher
5
Das, AM
4
Cirino, Giuseppe
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All Publications
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2009: Bolton Christopher; Wood Elizabeth G; Scott Gwen S; Flower Roderick J
A comparative evaluation of the response to peroxynitrite by a brain endothelial cell line and control of the effects by drug targeting.
Cellular and molecular neurobiology 2009;29(5):707-17.
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2009: Huggins Anthony; Paschalidis Nikolaos; Flower Roderick J; Perretti Mauro; D'Acquisto Fulvio
Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(4):985-96.
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2009: Gastardelo Thaís Santana; Damazo Amílcar Sabino; Dalli Jesmond; Flower Roderick J; Perretti Mauro; Oliani Sonia Maria
Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation.
The American journal of pathology 2009;174(1):177-83.
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2008: Ayoub S S; Yazid S; Flower R J
Increased susceptibility of annexin-A1 null mice to nociceptive pain is indicative of a spinal antinociceptive action of annexin-A1.
British journal of pharmacology 2008;154(5):1135-42.
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2008: D'Acquisto F; Paschalidis N; Raza K; Buckley C D; Flower R J; Perretti M
Glucocorticoid treatment inhibits annexin-1 expression in rheumatoid arthritis CD4+ T cells.
Rheumatology (Oxford, England) 2008;47(5):636-9.
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2008: Damazo A S; Flower R J; Solito E; Oliani S M
Annexin-A1 gene expression during liver development and post-translation modification after experimental endotoxemia.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2008;57(3):97-103.
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2007: Gavins Felicity N E; Dalli Jesmond; Flower Roderick J; Granger D Neil; Perretti Mauro
Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(8):1751-8.
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2007: D'Acquisto Fulvio; Merghani Ahmed; Lecona Emilio; Rosignoli Guglielmo; Raza Karim; Buckley Christopher D; Flower Roderick J; Perretti Mauro
Annexin-1 modulates T-cell activation and differentiation.
Blood 2007;109(3):1095-102.
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2006: Yona Simon; Heinsbroek Sigrid E M; Peiser Leanne; Gordon Siamon; Perretti Mauro; Flower Roderick J
Impaired phagocytic mechanism in annexin 1 null macrophages.
British journal of pharmacology 2006;148(4):469-77.
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2006: Damazo Amilcar S; Yona Simon; Flower Roderick J; Perretti Mauro; Oliani Sonia M
Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(7):4410-8.
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2006: Hayhoe Richard P G; Kamal Ahmad M; Solito Egle; Flower Roderick J; Cooper Dianne; Perretti Mauro
Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement.
Blood 2006;107(5):2123-30.
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2006: Flower R J
Prostaglandins, bioassay and inflammation.
British journal of pharmacology 2006;147 Suppl 1():S182-92.
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2006: Kamal Ahmad M; Hayhoe Richard P G; Paramasivam Anbalakan; Cooper Dianne; Flower Roderick J; Solito Egle; Perretti Mauro
Antiflammin-2 activates the human formyl-peptide receptor like 1.
TheScientificWorldJournal 2006;6():1375-84.
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2005: Moraes Leonardo A; Paul-Clark Mark J; Rickman Alice; Flower Roderick J; Goulding Nicolas J; Perretti Mauro
Ligand-specific glucocorticoid receptor activation in human platelets.
Blood 2005;106(13):4167-75.
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2005: Chatterjee Bristi E; Yona Simon; Rosignoli Guglielmo; Young Rebecca E; Nourshargh Sussan; Flower Roderick J; Perretti Mauro
Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro.
Journal of leukocyte biology 2005;78(3):639-46.
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2005: Damazo Amilcar S; Yona Simon; D'Acquisto Fulvio; Flower Roderick J; Oliani Sonia M; Perretti Mauro
Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation.
The American journal of pathology 2005;166(6):1607-17.
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2005: Flower Roderick J; Perretti Mauro
Controlling inflammation: a fat chance?
The Journal of experimental medicine 2005;201(5):671-4.
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2005: Yona S; Ward Barbara; Buckingham Julia C; Perretti M; Flower R J
Macrophage biology in the Anx-A1-/- mouse.
Prostaglandins, leukotrienes, and essential fatty acids 2005;72(2):95-103.
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2004: Yona Simon; Buckingham Julia C; Perretti Mauro; Flower Roderick J
Stimulus-specific defect in the phagocytic pathways of annexin 1 null macrophages.
British journal of pharmacology 2004;142(5):890-8.
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2004: Yang Yuan H; Morand Eric F; Getting Stephen J; Paul-Clark Mark; Liu Dong L; Yona Simon; Hannon Robert; Buckingham Julia C; Perretti Mauro; Flower Roderick J
Modulation of inflammation and response to dexamethasone by Annexin 1 in antigen-induced arthritis.
Arthritis and rheumatism 2004;50(3):976-84.
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2003: Paul-Clark Mark J; Roviezzo Fiorentina; Flower Roderick J; Cirino Giuseppe; Soldato Piero Del; Adcock Ian M; Perretti Mauro
Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):3245-52.
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2003: Perretti M; Paul-Clark M J; Mancini L; Flower R J
Generation of innovative anti-inflammatory and anti-arthritic glucocorticoid derivatives that release NO: the nitro-steroids.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2003;35 Suppl 2():S41-8.
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2003: Gavins Felicity N E; Yona Simon; Kamal Ahmad M; Flower Roderick J; Perretti Mauro
Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms.
Blood 2003;101(10):4140-7.
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2003: Croxtall Jamie D; Gilroy Derek W; Solito Egle; Choudhury Qamrul; Ward Barbara J; Buckingham Julia C; Flower Rod J
Attenuation of glucocorticoid functions in an Anx-A1-/- cell line.
The Biochemical journal 2003;371(Pt 3):927-35.
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2003: Getting Stephen J; Christian Helen C; Lam Connie W; Gavins Felicity N E; Flower Roderick J; Schiöth Helgi B; Perretti Mauro
Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):3323-30.
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2003: Flower Rod J
The development of COX2 inhibitors.
Nature reviews. Drug discovery 2003;2(3):179-91.
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2003: Hannon Robert; Croxtall Jamie D; Getting Steve J; Roviezzo Fiorita; Yona Simon; Paul-Clark Mark J; Gavins Felicity N E; Perretti Mauro; Morris John F; Buckingham Julia C; Flower Roderick J
Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(2):253-5.
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2002: Roviezzo F; Getting S J; Paul-Clark M J; Yona S; Gavins F N E; Perretti M; Hannon R; Croxtall J D; Buckingham J C; Flower R J
The annexin-1 knockout mouse: what it tells us about the inflammatory response.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2002;53(4 Pt 1):541-53.
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2002: Getting Stephen J; Christian Helen C; Flower Roderick J; Perretti Mauro
Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis.
Arthritis and rheumatism 2002;46(10):2765-75.
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2002: Paul-Clark Mark J; Mancini Lucia; Del Soldato Piero; Flower Roderick J; Perretti Mauro
Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1677-82.
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2002: Croxtall Jamie D; van Hal Peter Th W; Choudhury Qam; Gilroy Derek W; Flower Rod J
Different glucocorticoids vary in their genomic and non-genomic mechanism of action in A549 cells.
British journal of pharmacology 2002;135(2):511-9.
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2002: Choudhury Qamrul G; Mckay Diane T; Flower Roderick J; Croxtall Jamie D
Investigation into the involvement of phospholipases A2 and map kinases in modulation of AA release and cell growth in A549 cells.
Advances in experimental medicine and biology 2002;507():33-40.
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2001: La M; D'Amico M; Bandiera S; Di Filippo C; Oliani S M; Gavins F N; Flower R J; Perretti M
Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(12):2247-56.
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2001: Oliani S M; Paul-Clark M J; Christian H C; Flower R J; Perretti M
Neutrophil interaction with inflamed postcapillary venule endothelium alters annexin 1 expression.
The American journal of pathology 2001;158(2):603-15.
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2000: Paul-Clark M; Del Soldato P; Fiorucci S; Flower R J; Perretti M
21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties.
British journal of pharmacology 2000;131(7):1345-54.
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2000: D'Amico M; Di Filippo C; La M; Solito E; McLean P G; Flower R J; Oliani S M; Perretti M
Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocyte recruitment.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(13):1867-9.
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2000: Oliani S M; Christian H C; Manston J; Flower R J; Perretti M
An immunocytochemical and in situ hybridization analysis of annexin 1 expression in rat mast cells: modulation by inflammation and dexamethasone.
Laboratory investigation; a journal of technical methods and pathology 2000;80(9):1429-38.
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2000: Choudhury Q G; McKay D T; Flower R J; Croxtall J D
Investigation into the involvement of phospholipases A(2) and MAP kinases in modulation of AA release and cell growth in A549 cells.
British journal of pharmacology 2000;131(2):255-65.
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2000: Lim L H; Flower R J; Perretti M; Das A M
Glucocorticoid receptor activation reduces CD11b and CD49d levels on murine eosinophils: characterization and functional relevance.
American journal of respiratory cell and molecular biology 2000;22(6):693-701.
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2000: Croxtall J D; Choudhury Q; Flower R J
Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism.
British journal of pharmacology 2000;130(2):289-98.
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2000: Canaider S; Solito E; de Coupade C; Flower R J; Russo-Marie F; Goulding N J; Perretti M
Increased apoptosis in U937 cells over-expressing lipocortin 1 (annexin I).
Life sciences 2000;66(18):PL265-70.
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2000: Perretti M; Christian H; Wheller S K; Aiello I; Mugridge K G; Morris J F; Flower R J; Goulding N J
Annexin I is stored within gelatinase granules of human neutrophil and mobilized on the cell surface upon adhesion but not phagocytosis.
Cell biology international 2000;24(3):163-74.
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1999: Getting S J; Flower R J; Perretti M
Agonism at melanocortin receptor type 3 on macrophages inhibits neutrophil influx.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48 Suppl 2():S140-1.
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1999: Tailor A; Tomlinson A; Salas A; Panés J; Granger D N; Flower R J; Perretti M
Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC.
Gut 1999;45(5):705-12.
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1999: Das A M; Ajuebor M N; Flower R J; Perretti M; McColl S R
Contrasting roles for RANTES and macrophage inflammatory protein-1 alpha (MIP-1 alpha) in a murine model of allergic peritonitis.
Clinical and experimental immunology 1999;117(2):223-9.
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1999: Getting S J; Gibbs L; Clark A J; Flower R J; Perretti M
POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7446-53.
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1999: Perretti M; Wheller S K; Flower R J; Wahid S; Pitzalis C
Modulation of cellular annexin I in human leukocytes infiltrating DTH skin reactions.
Journal of leukocyte biology 1999;65(5):583-9.
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1999: Ajuebor M N; Das A M; Virág L; Flower R J; Szabó C; Perretti M
Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1685-91.
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1999: Euzger H S; Flower R J; Goulding N J; Perretti M
Differential modulation of annexin I binding sites on monocytes and neutrophils.
Mediators of inflammation 1999;8(1):53-62.
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1998: Ajuebor M N; Virág L; Flower R J; Perretti M; Szabó C
Role of inducible nitric oxide synthase in the regulation of neutrophil migration in zymosan-induced inflammation.
Immunology 1998;95(4):625-30.
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1998: Lim L H; Solito E; Russo-Marie F; Flower R J; Perretti M
Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14535-9.
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1998: Ajuebor M N; Gibbs L; Flower R J; Das A M; Perretti M
Investigation of the functional role played by the chemokine monocyte chemoattractant protein-1 in interleukin-1-induced murine peritonitis.
British journal of pharmacology 1998;125(2):319-26.
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1998: Das A M; Flower R J; Perretti M
Resident mast cells are important for eotaxin-induced eosinophil accumulation in vivo.
Journal of leukocyte biology 1998;64(2):156-62.
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1998: Solito E; de Coupade C; Parente L; Flower R J; Russo-Marie F
IL-6 stimulates annexin 1 expression and translocation and suggests a new biological role as class II acute phase protein.
Cytokine 1998;10(7):514-21.
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1998: Solito E; de Coupade C; Parente L; Flower R J; Russo-Marie F
Human annexin 1 is highly expressed during the differentiation of the epithelial cell line A 549: involvement of nuclear factor interleukin 6 in phorbol ester induction of annexin 1.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(4):327-36.
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1998: Croxtall J D; Choudhury Q; Flower R J
Inhibitory effect of peptides derived from the N-terminus of lipocortin 1 on arachidonic acid release and proliferation in the A549 cell line: identification of E-Q-E-Y-V as a crucial component.
British journal of pharmacology 1998;123(5):975-83.
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1998: Bryant C E; Perretti M; Flower R J
Suppression by dexamethasone of inducible nitric oxide synthase protein expression in vivo: a possible role for lipocortin 1.
Biochemical pharmacology 1998;55(3):279-85.
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1998: Ajuebor M N; Flower R J; Hannon R; Christie M; Bowers K; Verity A; Perretti M
Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model.
Journal of leukocyte biology 1998;63(1):108-16.
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1997: Croxtall J D; Choudhury Q; White J O; Flower R J
Tamoxifen inhibits the release of arachidonic acid stimulated by thapsigargin in estrogen receptor-negative A549 cells.
Biochimica et biophysica acta 1997;1349(3):275-84.
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1997: Willmott N J; Choudhury Q; Flower R J
Effects of dexamethasone and phorbol ester on P2 receptor-coupled Ca2+ signalling and lipocortin 1 presentation in U937 cells.
British journal of pharmacology 1997;122(6):1055-60.
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1997: Getting S J; Flower R J; Parente L; de Medicis R; Lussier A; Woliztky B A; Martins M A; Perretti M
Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins.
The Journal of pharmacology and experimental therapeutics 1997;283(1):123-30.
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1997: Tailor A; Flower R J; Perretti M
Dexamethasone inhibits leukocyte emigration in rat mesenteric post-capillary venules: an intravital microscopy study.
Journal of leukocyte biology 1997;62(3):301-8.
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1997: Das A M; Flower R J; Perretti M
Eotaxin-induced eosinophil migration in the peritoneal cavity of ovalbumin-sensitized mice: mechanism of action.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(3):1466-73.
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1997: Das A M; Flower R J; Hellewell P G; Teixeira M M; Perretti M
A novel murine model of allergic inflammation to study the effect of dexamethasone on eosinophil recruitment.
British journal of pharmacology 1997;121(1):97-104.
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1997: Getting S J; Flower R J; Perretti M
Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1.
British journal of pharmacology 1997;120(6):1075-82.
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1997: Tailor A; Das A M; Getting S J; Flower R J; Perretti M
Subacute treatment of rats with dexamethasone reduces ICAM-1 levels on circulating monocytes.
Biochemical and biophysical research communications 1997;231(3):675-8.
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1997: Newman S P; Croxtall J D; Choudhury Q; Flower R J
The co-ordinate regulation of lipocortin 1, COX 2 and cPLA2 by IL-1 beta in A549 cells.
Advances in experimental medicine and biology 1997;407():249-53.
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1996: Perretti M; Croxtall J D; Wheller S K; Goulding N J; Hannon R; Flower R J
Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration.
Nature medicine 1996;2(11):1259-62.
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1996: Croxtall J D; Choudhury Q; Newman S; Flower R J
Lipocortin 1 and the control of cPLA2 activity in A549 cells. Glucocorticoids block EGF stimulation of cPLA2 phosphorylation.
Biochemical pharmacology 1996;52(2):351-6.
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1996: Perretti M; Flower R J
Measurement of lipocortin 1 levels in murine peripheral blood leukocytes by flow cytometry: modulation by glucocorticoids and inflammation.
British journal of pharmacology 1996;118(3):605-10.
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1996: Perretti M; Wheller S K; Harris J G; Flower R J
Modulation of ICAM-1 levels on U-937 cells and mouse macrophages by interleukin-1 beta and dexamethasone.
Biochemical and biophysical research communications 1996;223(1):112-7.
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1996: Harris J G; Flower R J; Watanabe K; Tsurufuji S; Wolitzky B A; Perretti M
Relative contribution of the selectins in the neutrophil recruitment caused by the chemokine cytokine-induced neutrophil chemoattractant (CINC).
Biochemical and biophysical research communications 1996;221(3):692-6.
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1996: Perretti M; Ahluwalia A; Harris J G; Harris H J; Wheller S K; Flower R J
Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1.
British journal of pharmacology 1996;117(6):1145-54.
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1996: Croxtal J D; Newman S P; Choudhury Q; Flower R J
The concerted regulation of cPLA2, COX2, and lipocortin 1 expression by IL-1beta in A549 cells.
Biochemical and biophysical research communications 1996;220(3):491-5.
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1995: Perretti M; Wheller S K; Choudhury Q; Croxtall J D; Flower R J
Selective inhibition of neutrophil function by a peptide derived from lipocortin 1 N-terminus.
Biochemical pharmacology 1995;50(7):1037-42.
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1995: Harris J G; Flower R J; Perretti M
Endogenous corticosteroids mediate the neutrophilia caused by platelet-activating factor in the mouse.
European journal of pharmacology 1995;283(1-3):9-18.
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1995: Ahluwalia A; Newbold P; Brain S D; Flower R J
Topical glucocorticoids inhibit neurogenic inflammation: involvement of lipocortin 1.
European journal of pharmacology 1995;283(1-3):193-8.
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1995: Croxtall J D; Choudhury Q; Tokumoto H; Flower R J
Lipocortin-1 and the control of arachidonic acid release in cell signalling. Glucocorticoids (changed from glucorticoids) inhibit G protein-dependent activation of cPLA2 activity.
Biochemical pharmacology 1995;50(4):465-74.
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1995: Mancuso F; Flower R J; Perretti M
Leukocyte transmigration, but not rolling or adhesion, is selectively inhibited by dexamethasone in the hamster post-capillary venule. Involvement of endogenous lipocortin 1.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(1):377-86.
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1995: Smith S F; Tetley T D; Datta A K; Smith T; Guz A; Flower R J
Lipocortin-1 distribution in bronchoalveolar lavage from healthy human lung: effect of prednisolone.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;79(1):121-8.
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1995: Harris J G; Flower R J; Perretti M
Alteration of neutrophil trafficking by a lipocortin 1 N-terminus peptide.
European journal of pharmacology 1995;279(2-3):149-57.
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1995: Wu C C; Croxtall J D; Perretti M; Bryant C E; Thiemermann C; Flower R J; Vane J R
Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3473-7.
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1995: Peers S H; Duncan G S; Flower R J; Bolton C
Endogenous corticosteroids modulate lymphoproliferation and susceptibility to experimental allergic encephalomyelitis in the Brown Norway rat.
International archives of allergy and immunology 1995;106(1):20-4.
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1995: Flower R J
New frontiers in the pharmacotherapy of inflammation.
Agents and actions. Supplements 1995;46():169-78.
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1995: Perretti M; Flower R J
Anti-inflammatory lipocortin-derived peptides.
Agents and actions. Supplements 1995;46():131-8.
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1994: Croxtall J D; Flower R J
Antisense oligonucleotides to human lipocortin-1 inhibit glucocorticoid-induced inhibition of A549 cell growth and eicosanoid release.
Biochemical pharmacology 1994;48(9):1729-34.
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1994: Ahluwalia A; Mohamed R W; Flower R J
Induction of lipocortin 1 by topical steroid in rat skin.
Biochemical pharmacology 1994;48(8):1647-54.
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1994: Newman S P; Flower R J; Croxtall J D
Dexamethasone suppression of IL-1 beta-induced cyclooxygenase 2 expression is not mediated by lipocortin-1 in A549 cells.
Biochemical and biophysical research communications 1994;202(2):931-9.
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1994: Perretti M; Flower R J
Cytokines, glucocorticoids and lipocortins in the control of neutrophil migration.
Pharmacological research : the official journal of the Italian Pharmacological Society 1994;30(1):53-9.
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1994: Perretti M; Harris J G; Flower R J
A role for endogenous histamine in interleukin-8-induced neutrophil infiltration into mouse air-pouch: investigation of the modulatory action of systemic and local dexamethasone.
British journal of pharmacology 1994;112(3):801-8.
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1994: Flower R J; Rothwell N J
Lipocortin-1: cellular mechanisms and clinical relevance.
Trends in pharmacological sciences 1994;15(3):71-6.
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1994: Tokumoto H; Croxtall J D; Flower R J
Differential role of extra- and intracellular calcium in bradykinin and interleukin 1 alpha stimulation of arachidonic acid release from A549 cells.
Biochimica et biophysica acta 1994;1211(3):301-9.
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1994: Croxtall J D; Emmas C; White J O; Choudhary Q; Flower R J
Tamoxifen inhibits growth of oestrogen receptor-negative A549 cells.
Biochemical pharmacology 1994;47(2):197-202.
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1993: Elderfield A J; Bolton C; Flower R J
Lipocortin 1 (annexin 1) immunoreactivity in the cervical spinal cord of Lewis rats with acute experimental allergic encephalomyelitis.
Journal of the neurological sciences 1993;119(2):146-53.
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1993: Perretti M; Ahluwalia A; Harris J G; Goulding N J; Flower R J
Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(8):4306-14.
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1993: Perretti M; Duncan G S; Flower R J; Peers S H
Serum corticosterone, interleukin-1 and tumour necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wistar strains.
British journal of pharmacology 1993;110(2):868-74.
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1993: Tokumoto H; Croxtall J D; Choudhury Q; Flower R J
Phospholipase A2-induced stimulation of A549 lung adenocarcinoma cell line proliferation.
Biochimica et biophysica acta 1993;1169(3):236-42.
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1993: Perretti M; Ahluwalia A; Flower R J; Manzini S
Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors.
Immunology 1993;80(1):73-7.
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1993: Peers S H; Duncan G S; Flower R J
Development of specific antibody and in vivo response to antigen in different rat strains: effect of dexamethasone and importance of endogenous corticosteroids.
Agents and actions 1993;39(3-4):174-81.
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1993: Perretti M; Flower R J; Goulding N J
The ability of murine leukocytes to bind lipocortin 1 is lost during acute inflammation.
Biochemical and biophysical research communications 1993;192(2):345-50.
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1993: Croxtall J D; Waheed S; Choudhury Q; Anand R; Flower R J
N-terminal peptide fragments of lipocortin-1 inhibit A549 cell growth and block EGF-induced stimulation of proliferation.
International journal of cancer. Journal international du cancer 1993;54(1):153-8.
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1993: Ahluwalia A; Flower R J
Investigations into the mechanism of vasoconstrictor action of the topical steroid betamethasone-17-valerate in the rat.
British journal of pharmacology 1993;108(2):544-8.
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1993: Perretti M; Flower R J
Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(3):992-9.
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1993: Peers S H; Smillie F; Elderfield A J; Flower R J
Glucocorticoid-and non-glucocorticoid induction of lipocortins (annexins) 1 and 2 in rat peritoneal leucocytes in vivo.
British journal of pharmacology 1993;108(1):66-72.
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1993: Duncan G S; Peers S H; Carey F; Forder R; Flower R J
The local anti-inflammatory action of dexamethasone in the rat carrageenin oedema model is reversed by an antiserum to lipocortin 1.
British journal of pharmacology 1993;108(1):62-5.
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1993: Ahluwalia A; Flower R J
Topical betamethasone-17-valerate inhibits heat-induced vasodilatation in man.
The British journal of dermatology 1993;128(1):45-8.
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1993: Perretti M; Appleton I; Parente L; Flower R J
Pharmacology of interleukin-1-induced neutrophil migration.
Agents and actions 1993;38 Spec No():C64-5.
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1993: Ahluwalia A; Flower R J
Effect of chronic capsaicin and guanethidine treatment on skin blood flow of the rat.
Agents and actions 1993;38 Spec No():C16-8.
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1992: Murphy C T; Peers S H; Forder R A; Flower R J; Carey F; Westwick J
Evidence for the presence and location of annexins in human platelets.
Biochemical and biophysical research communications 1992;189(3):1739-46.
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1992: Podgorski M R; Goulding N J; Hall N D; Flower R J; Maddison P J
Autoantibodies to lipocortin-1 are associated with impaired glucocorticoid responsiveness in rheumatoid arthritis.
The Journal of rheumatology 1992;19(11):1668-71.
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1992: Douglas G J; Flower R J; Parente L; Perretti M
Peptide 204-212 of lipocortin 5 inhibits the generation of a prostacyclin-like factor from rat aorta preparations in vitro.
Prostaglandins 1992;44(5):381-8.
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1992: Elderfield A J; Newcombe J; Bolton C; Flower R J
Lipocortins (annexins) 1, 2, 4 and 5 are increased in the central nervous system in multiple sclerosis.
Journal of neuroimmunology 1992;39(1-2):91-100.
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1992: Ahluwalia A; Peers S H; Flower R J
Steroid inhibition of oedema formation in the rat skin.
British journal of pharmacology 1992;106(3):628-31.
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1992: Croxtall J D; Flower R J
Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(8):3571-5.
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1991: Douglas G J; Williams K I; Flower R J
Characterization of Gaddum's substance R.
British journal of pharmacology 1991;102(4):926-30.
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1991: Peers S H; Flower R J
Site of anti-inflammatory action of dexamethasone in rabbit skin.
European journal of pharmacology 1991;196(1):37-41.
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1991: Chung K F; Podgorski M R; Goulding N J; Godolphin J L; Sharland P R; O'Connor B; Flower R J; Barnes P J
Circulating autoantibodies to recombinant lipocortin-1 in asthma.
Respiratory medicine 1991;85(2):121-4.
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1990: Rivers J K; Podgorski M R; Goulding N J; Wong E; McGrath J A; Flower R J; Greaves M W
The presence of autoantibody to recombinant lipocortin-I in patients with psoriasis and psoriatic arthritis.
The British journal of dermatology 1990;123(5):569-72.
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1990: Bolton C; Elderfield A J; Flower R J
The detection of lipocortins 1, 2 and 5 in central nervous system tissues from Lewis rats with acute experimental allergic encephalomyelitis.
Journal of neuroimmunology 1990;29(1-3):173-81.
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1990: Smith S F; Goulding N J; Godolphin J L; Tetley T D; Roberts C M; Guz A; Flower R J
An assay for the assessment of lipocortin 1 levels in human lung lavage fluid.
Journal of immunological methods 1990;131(1):119-25.
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1990: Goulding N J; Godolphin J L; Sharland P R; Peers S H; Sampson M; Maddison P J; Flower R J
Anti-inflammatory lipocortin 1 production by peripheral blood leucocytes in response to hydrocortisone.
Lancet 1990;335(8703):1416-8.
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1990: Smith S F; Tetley T D; Guz A; Flower R J
Detection of lipocortin 1 in human lung lavage fluid: lipocortin degradation as a possible proteolytic mechanism in the control of inflammatory mediators and inflammation.
Environmental health perspectives 1990;85():135-44.
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1990: Goulding N J; Godolphin J L; Sampson M B; Maddison P J; Flower R J
Hydrocortisone induces lipocortin 1 production by peripheral blood mononuclear cells in vivo in man.
Biochemical Society transactions 1990;18(2):306-7.
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1990: Peers S H; Flower R J
The role of lipocortin in corticosteroid actions.
The American review of respiratory disease 1990;141(2 Pt 2):S18-21.
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1989: Goulding N J; Podgorski M R; Hall N D; Flower R J; Browning J L; Pepinsky R B; Maddison P J
Autoantibodies to recombinant lipocortin-1 in rheumatoid arthritis and systemic lupus erythematosus.
Annals of the rheumatic diseases 1989;48(10):843-50.
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1989: Cirino G; Peers S H; Wallace J L; Flower R J
A study of phospholipase A2-induced oedema in rat paw.
European journal of pharmacology 1989;166(3):505-10.
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1989: Cirino G; Peers S H; Flower R J; Browning J L; Pepinsky R B
Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3428-32.
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1989: Bolton C; Flower R J
The effects of the anti-glucocorticoid RU 38486 on steroid-mediated suppression of experimental allergic encephalomyelitis (EAE) in the Lewis rat.
Life sciences 1989;45(1):97-104.
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1988: Flower R J
Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids.
British journal of pharmacology 1988;94(4):987-1015.
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1988: Peers S H; Moon D; Flower R J
Reversal of the anti-inflammatory effects of dexamethasone by the glucocorticoid antagonist RU 38486.
Biochemical pharmacology 1988;37(3):556-7.
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1987: Peers S H; Taylor R D; Flower R J
A novel binding assay for phospholipase A2.
Biochemical pharmacology 1987;36(24):4287-91.
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1987: Cirino G; Flower R J
Human recombinant lipocortin 1 inhibits prostacyclin production by human umbilical artery in vitro.
Prostaglandins 1987;34(1):59-62.
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1987: Flower R J
Lipocortins.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17A():577-80.
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