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Gert Folkerts

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Saskia A Overbeek; Wim Timens; Gerry T M Wagenaar; J Edwin Blalock; Saskia Braber; Johan Garssen; Paul A J Henricks; Patricia L Jackson; Pim J Koelink; Leo Koenderman; Aletta D Kraneveld; Adele T LoTam Loi; Esmaeil Mortaz; Gert Folkerts
Cigarette smoke-induced collagen destruction; key to chronic neutrophilic airway inflammation?
Johannes M van Noort; Sandra Amor; Erik Boddeke; Malika Bsibsi; Gert Folkerts; Wouter H Gerritsen; Wim E Hennink; Inge R Holtman; Thea Leusink-Muis; Peter J Nacken; Ingrid van Ark; Maryam Amidi
Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA microparticles.
Saskia A Overbeek; Fabio L Ricciardolo; Johan Garssen; Niki A Georgiou; P A J Henricks; Vera M Kamp; Marije Kleinjan; Aletta D Kraneveld; Gert Folkerts
Chemo-attractant N-acetyl proline-glycine-proline induces CD11b/CD18-dependent neutrophil adhesion.

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All Publications

2013: Saskia A Overbeek; Wim Timens; Gerry T M Wagenaar; J Edwin Blalock; Saskia Braber; Johan Garssen; Paul A J Henricks; Patricia L Jackson; Pim J Koelink; Leo Koenderman; Aletta D Kraneveld; Adele T LoTam Loi; Esmaeil Mortaz; Gert Folkerts
Cigarette smoke-induced collagen destruction; key to chronic neutrophilic airway inflammation?
PloS one 2013;8(1):e55612.
2013: Johannes M van Noort; Sandra Amor; Erik Boddeke; Malika Bsibsi; Gert Folkerts; Wouter H Gerritsen; Wim E Hennink; Inge R Holtman; Thea Leusink-Muis; Peter J Nacken; Ingrid van Ark; Maryam Amidi
Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA microparticles.
Biomaterials 2013;34(3):831-40.
2013: Saskia A Overbeek; Fabio L Ricciardolo; Johan Garssen; Niki A Georgiou; P A J Henricks; Vera M Kamp; Marije Kleinjan; Aletta D Kraneveld; Gert Folkerts
Chemo-attractant N-acetyl proline-glycine-proline induces CD11b/CD18-dependent neutrophil adhesion.
Biochimica et biophysica acta 2013;1830(1):2188-93.
2012: Fabio L M Ricciardolo; Andrea Robotti; Federica Sabatini; Valentina Sorbello; Dein C van Renswouw; Sabrina Benedetto; Caterina Bucca; Ilaria Defilippi; Gert Folkerts; Virginia De Rose
Bradykinin- and lipopolysaccharide-induced bradykinin B2 receptor expression, interleukin 8 release and "nitrosative stress" in bronchial epithelial cells BEAS-2B: role for neutrophils.
European journal of pharmacology 2012;694(1-3):30-8.
2012: Esmaeil Mortaz; Carla A Da Silva; Gert Folkerts; Masoumeh E Givi; Frank A Redegeld
A relation between TGF-β and mast cell tryptase in experimental emphysema models.
Biochimica et biophysica acta 2012;1822(7):1154-60.
2012: Gillina F G Bezemer; Johan Garssen; Niki A Georgiou; Aletta D Kraneveld; Seil Sagar; Jeroen van Bergenhenegouwen; Gert Folkerts
Dual role of Toll-like receptors in asthma and chronic obstructive pulmonary disease.
Pharmacological reviews 2012;64(2):337-58.
2012: Masoumeh Ezzati Givi; Gert Folkerts; Frank A Redegeld; Esmaeil Mortaz
Dendritic cells in pathogenesis of COPD.
Current pharmaceutical design 2012;18(16):2329-35.
2012: Aletta D Kraneveld; Seil Sagar; Johan Garssen; Gert Folkerts
The two faces of mast cells in food allergy and allergic asthma: the possible concept of Yin Yang.
Biochimica et biophysica acta 2012;1822(1):93-9.
2011: Maiwand Nazary; Errol P Prens; H H van der Zee; Gert Folkerts; Jurr Boer
Pathogenesis and pharmacotherapy of Hidradenitis suppurativa.
European journal of pharmacology 2011;672(1-3):1-8.
2011: Sven van Eijl; Ana F Ferreira; Gert Folkerts; Frieke Kuper; Esmaeil Mortaz; Frans P Nijkamp; Nanne Bloksma
Humic acid enhances cigarette smoke-induced lung emphysema in mice and IL-8 release of human monocytes.
Pulmonary pharmacology & therapeutics 2011;24(6):682-9.
2011: Saskia Braber; Johan Garssen; P A J Henricks; Pim J Koelink; Aletta D Kraneveld; Saskia A Overbeek; Guido J R Zaman; Gert Folkerts
CXCR2 antagonists block the N-Ac-PGP-induced neutrophil influx in the airways of mice, but not the production of the chemokine CXCL1.
European journal of pharmacology 2011;668(3):443-9.
2011: Saskia A Overbeek; Martine J Smit; Anja I Srienc; Guido J R Zaman; Johan Garssen; P A J Henricks; Pim J Koelink; Aletta D Kraneveld; Herman D Lim; Frans P Nijkamp; Petra de Kruijf; Gert Folkerts
N-acetylated Proline-Glycine-Proline induced G-protein dependent chemotaxis of neutrophils is independent of CXCL8 release.
European journal of pharmacology 2011;668(3):428-34.
2011: Esmaeil Mortaz; Johan Garssen; M E Givi; P A J Henricks; Aletta D Kraneveld; Gert Folkerts
Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and induction of the inflammasome.
Biochimica et biophysica acta 2011;1812(9):1104-10.
2011: Esmaeil Mortaz; Gert Folkerts; Frank Redegeld
Mast cells and COPD.
Pulmonary pharmacology & therapeutics 2011;24(4):367-72.
2011: Joris Kloek; Esmaeil Mortaz; Ingrid van Ark; Nanne Bloksma; Johan Garssen; Frans P Nijkamp; Gert Folkerts
A whey-based glutathione-enhancing diet decreases allergen-induced airway contraction in a guinea-pig model of asthma.
The British journal of nutrition 2011;105(10):1465-70.
2011: S van Eijl; C Versluis; Gert Folkerts; Esmaeil Mortaz; Frans P Nijkamp; Nanne Bloksma
A low vitamin A status increases the susceptibility to cigarette smoke-induced lung emphysema in C57BL/6J mice.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2011;62(2):175-82.
2011: Saskia Braber; Pim J Koelink; P A J Henricks; Patricia L Jackson; Frans P Nijkamp; Johan Garssen; Aletta D Kraneveld; J Edwin Blalock; Gert Folkerts
Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.
American journal of physiology. Lung cellular and molecular physiology 2011;300(2):L255-65.
2011: Saskia A Overbeek; Saskia Braber; Johan Garssen; Niki A Georgiou; P A J Henricks; Vera M Kamp; Marije Kleinjan; Aletta D Kraneveld; Gert Folkerts
Cigarette smoke induces β2-integrin-dependent neutrophil migration across human endothelium.
Respiratory research 2011;12():75.
2010: S Braber; K A T Verheijden; P A J Henricks; Aletta D Kraneveld; Gert Folkerts
A comparison of fixation methods on lung morphology in a murine model of emphysema.
American journal of physiology. Lung cellular and molecular physiology 2010;299(6):L843-51.
2010: Esmaeil Mortaz; I M Adcock; K Ito; Aletta D Kraneveld; Frans P Nijkamp; Gert Folkerts
Cigarette smoke induces CXCL8 production by human neutrophils via activation of TLR9 receptor.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010;36(5):1143-54.
2010: Esmaeil Mortaz; Gert Folkerts; Frans P Nijkamp; P A J Henricks
ATP and the pathogenesis of COPD.
European journal of pharmacology 2010;638(1-3):1-4.
2010: Hadi Sarir; Esmaeil Mortaz; Willem T Janse; Masoumeh E Givi; Frans P Nijkamp; Gert Folkerts
IL-8 production by macrophages is synergistically enhanced when cigarette smoke is combined with TNF-alpha.
Biochemical pharmacology 2010;79(5):698-705.
2010: J Kloek; Esmaeil Mortaz; Ingrid van Ark; C M Lilly; F P Nijkamp; Gert Folkerts
Glutathione prevents the early asthmatic reaction and airway hyperresponsiveness in guinea pigs.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2010;61(1):67-72.
2010: Saskia Braber; P A J Henricks; Frans P Nijkamp; Aletta D Kraneveld; Gert Folkerts
Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation.
Respiratory research 2010;11():99.
2009: Esmaeil Mortaz; Saskia Braber; Maiwand Nazary; Masoumh Ezzati Givi; Frans P Nijkamp; Gert Folkerts
ATP in the pathogenesis of lung emphysema.
European journal of pharmacology 2009;619(1-3):92-6.
2009: Esmaeil Mortaz; Gert Folkerts; Ferdi Engels; Frans P Nijkamp; Frank A Redegeld
Cigarette smoke suppresses in vitro allergic activation of mouse mast cells.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(5):679-87.
2009: Esmaeil Mortaz; Zsofia Lazar; Leo Koenderman; Aletta D Kraneveld; Frans P Nijkamp; Gert Folkerts
Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation.
Respiratory research 2009;10():47.
2009: Hadi Sarir; Esmaeil Mortaz; Khalil Karimi; Aletta D Kraneveld; Irfan Rahman; Eric Caldenhoven; Frans P Nijkamp; Gert Folkerts
Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages.
Journal of inflammation (London, England) 2009;6():12.
2009: Esmaeil Mortaz; Aletta D Kraneveld; Joost J Smit; Mirjam Kool; Bart N Lambrecht; Steven Kunkel; Nicholas W Lukacs; Frans P Nijkamp; Gert Folkerts
Effect of cigarette smoke extract on dendritic cells and their impact on T-cell proliferation.
PloS one 2009;4(3):e4946.
2008: Esmaeil Mortaz; Mehdi Vaezi Rad; Malcolm Johnson; Danielle Raats; Frans P Nijkamp; Gert Folkerts
Salmeterol with fluticasone enhances the suppression of IL-8 release and increases the translocation of glucocorticoid receptor by human neutrophils stimulated with cigarette smoke.
Journal of molecular medicine (Berlin, Germany) 2008;86(9):1045-56.
2008: Anneke H van Houwelingen; Nathaniel M Weathington; Vivienne Verweij; J Edwin Blalock; Frans P Nijkamp; Gert Folkerts
Induction of lung emphysema is prevented by L-arginine-threonine-arginine.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(9):3403-8.
2008: Fabio L M Ricciardolo; Frans Nijkamp; Virginia De Rose; Gert Folkerts
The guinea pig as an animal model for asthma.
Current drug targets 2008;9(6):452-65.
2008: Hadi Sarir; P A J Henricks; Anneke H van Houwelingen; Frans P Nijkamp; Gert Folkerts
Cells, mediators and Toll-like receptors in COPD.
European journal of pharmacology 2008;585(2-3):346-53.
2008: Gert Folkerts; Aletta D Kraneveld; Frans P Nijkamp
New endogenous CXC chemokine ligands as potential targets in lung emphysema.
Trends in pharmacological sciences 2008;29(4):181-5.
2008: Bart P Van Putte; Marco Grootenboers; Wim-Jan van Boven; Jeroen Hendriks; Paul E Y Van Schil; Gunther Guetens; Gert De Boeck; Gerard Pasterkamp; Franz Schramel; Gert Folkerts
Pharmacokinetics of gemcitabine when delivered by selective pulmonary artery perfusion for the treatment of lung cancer.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(4):676-81.
2008: Esmaeil Mortaz; Frank A Redegeld; Hadi Sarir; Khalil Karimi; Danielle Raats; Frans P Nijkamp; Gert Folkerts
Cigarette smoke stimulates the production of chemokines in mast cells.
Journal of leukocyte biology 2008;83(3):575-80.
2007: Hadi Sarir; Esmaeil Mortaz; Khalil Karimi; Malcolm Johnson; Frans P Nijkamp; Gert Folkerts
Combination of fluticasone propionate and salmeterol potentiates the suppression of cigarette smoke-induced IL-8 production by macrophages.
European journal of pharmacology 2007;571(1):55-61.
2007: Francesco Blasi; Stefano Aliberti; Luigi Allegra; Gioia Piatti; Paolo Tarsia; Jacobus M Ossewaarde; Vivienne Verweij; Frans P Nijkamp; Gert Folkerts
Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice.
Respiratory research 2007;8():83.
2006: Bart P Van Putte; Jeroen Hendriks; Gunther Guetens; Gert de Boeck; Ernst A de Bruijn; Paul E Y Van Schil; Gert Folkerts
Modified approach of administering cytostatics to the lung: more efficient isolated lung perfusion.
The Annals of thoracic surgery 2006;82(3):1033-7.
2006: Fabio L M Ricciardolo; Frans P Nijkamp; Gert Folkerts
Nitric oxide synthase (NOS) as therapeutic target for asthma and chronic obstructive pulmonary disease.
Current drug targets 2006;7(6):721-35.
2006: Fabio L M Ricciardolo; Antonino Di Stefano; Federica Sabatini; Gert Folkerts
Reactive nitrogen species in the respiratory tract.
European journal of pharmacology 2006;533(1-3):240-52.
2006: Nathaniel M Weathington; Anneke H van Houwelingen; Brett D Noerager; Patricia L Jackson; Aletta D Kraneveld; F Shawn Galin; Gert Folkerts; Frans P Nijkamp; J Edwin Blalock
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.
Nature medicine 2006;12(3):317-23.
2006: Gert Folkerts; Frans P Nijkamp
Nitric oxide in asthma therapy.
Current pharmaceutical design 2006;12(25):3221-32.
2006: Khalil Karimi; Hadi Sarir; Esmaeil Mortaz; Joost J Smit; Hossein Hosseini; Sjef De Kimpe; Frans P Nijkamp; Gert Folkerts
Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages.
Respiratory research 2006;7():66.
2006: Robert Ten Broeke; Rini de Crom; Rien van Haperen; Vivienne Verweij; Thea Leusink-Muis; Ingrid van Ark; Fred De Clerck; Frans P Nijkamp; Gert Folkerts
Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice.
Respiratory research 2006;7():58.
2005: Bart P Van Putte; Albert Huisman; Jeroen Hendriks; Paul E Y Van Schil; Wim-Jan van Boven; Franz Schramel; Frans P Nijkamp; Gert Folkerts
Pulmonary intravascular volume can be used for dose calculation in isolated lung perfusion.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2005;28(4):594-8.
2004: Fabio L M Ricciardolo; Peter J Sterk; Benjamin Gaston; Gert Folkerts
Nitric oxide in health and disease of the respiratory system.
Physiological reviews 2004;84(3):731-65.
2004: Joost J Smit; Gert Folkerts; Frans P Nijkamp
Ramp-ing up allergies: Nramp1 (Slc11a1), macrophages and the hygiene hypothesis.
Trends in immunology 2004;25(7):342-7.
2004: Gert Folkerts; Frans P Nijkamp
Airway nitrergic pathways: is there therapeutic potential in asthma and COPD?
Current opinion in pharmacology 2004;4(3):202-6.
2004: Joost J Smit; Gert Folkerts; Frans P Nijkamp
Mycobacteria, genes and the 'hygiene hypothesis'.
Current opinion in allergy and clinical immunology 2004;4(1):57-62.
2004: Robert Ten Broeke; J Edwin Blalock; Frans P Nijkamp; Gert Folkerts
Calcium sensors as new therapeutic targets for asthma and chronic obstructive pulmonary disease.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(2):170-6.
2004: David A Groneberg; Gert Folkerts; Christian Peiser; K Fan Chung; Axel Fischer
Neuropeptide Y (NPY).
Pulmonary pharmacology & therapeutics 2004;17(4):173-80.
2004: Robert Ten Broeke; Thea Leusink-Muis; Rogier Hilberdink; Ingrid van Ark; Edwin van den Worm; Matteo Villain; Fred De Clerck; J Edwin Blalock; Frans P Nijkamp; Gert Folkerts
Specific modulation of calmodulin activity induces a dramatic production of superoxide by alveolar macrophages.
Laboratory investigation; a journal of technical methods and pathology 2004;84(1):29-40.
2003: Fabio L M Ricciardolo; MC Timmers; Jacob K Sont; Gert Folkerts; Peter J Sterk
Effect of bradykinin on allergen induced increase in exhaled nitric oxide in asthma.
Thorax 2003;58(10):840-5.
2003: Robert Ten Broeke; Marcel C Brandhorst; Thea Leusink-Muis; Matteo Villain; Fred De Clerck; J Edwin Blalock; Frans P Nijkamp; Gert Folkerts
Ca2+ sensors modulate asthmatic symptoms in an allergic model for asthma.
European journal of pharmacology 2003;476(1-2):151-7.
2003: Joost J Smit; Henk Van Loveren; Maarten O Hoekstra; Marcel A Schijf; Gert Folkerts; Frans P Nijkamp
Mycobacterium vaccae administration during allergen sensitization or challenge suppresses asthmatic features.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(8):1083-9.
2003: Joost J Smit; Henk Van Loveren; Maarten O Hoekstra; Khalil Karimi; Gert Folkerts; Frans P Nijkamp
The Slc11a1 (Nramp1) gene controls efficacy of mycobacterial treatment of allergic asthma.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):754-60.
2003: Joost J Smit; Henk Van Loveren; Maarten O Hoekstra; Patrick A A Van der Kant; Gert Folkerts; Frans P Nijkamp
Therapeutic treatment with heat-killed Mycobacterium vaccae (SRL172) in a mild and severe mouse model for allergic asthma.
European journal of pharmacology 2003;470(3):193-9.
2003: Joris Kloek; Ingrid van Ark; Fred De Clerck; Nanne Bloksma; Frans P Nijkamp; Gert Folkerts
Modulation of airway hyperresponsiveness by thiols in a murine in vivo model of allergic asthma.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52(3):126-31.
2002: Muriel Haag; Thea Leusink-Muis; Renaud Le Bouquin; Frans P Nijkamp; Alain Lugnier; Nelly Frossard; Gert Folkerts; Françoise Pons
Increased expression and decreased activity of cytochrome P450 1A1 in a murine model of toluene diisocyanate-induced asthma.
Archives of toxicology 2002;76(11):621-7.
2002: Judith Scheerens; Sandra B E van Gessel; Frans P Nijkamp; Gert Folkerts
Eotaxin protein levels and airway pathology in a mouse model for allergic asthma.
European journal of pharmacology 2002;453(1):111-7.
2002: G Sadeghi-Hashjin; Frans P Nijkamp; P A J Henricks; Gert Folkerts
Sodium cromoglycate and doxantrazole are oxygen radical scavengers.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;20(4):867-72.
2002: Joris Kloek; Ingrid van Ark; Nanne Bloksma; Fred De Clerck; Frans P Nijkamp; Gert Folkerts
Glutathione and other low-molecular-weight thiols relax guinea pig trachea ex vivo: interactions with nitric oxide?
American journal of physiology. Lung cellular and molecular physiology 2002;283(2):L403-8.
2002: Joris Kloek; Frans P Nijkamp; Nanne Bloksma; Fred De Clerck; Gert Folkerts
Differential responsiveness of proximal and distal parts of isolated guinea pig trachea.
European journal of pharmacology 2002;442(3):289-94.
2002: Axel Fischer; Gert Folkerts; Pierangelo Geppetti; David A Groneberg
Mediators of asthma: nitric oxide.
Pulmonary pharmacology & therapeutics 2002;15(2):73-81.
2002: R B R Muijsers; A van der Veeken; J Habernickel; Gert Folkerts; Dirkje S Postma; Frans P Nijkamp
Intra-luminal exposure of murine airways to peroxynitrite causes inflammation but not hyperresponsiveness.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51(1):33-7.
2001: Gert Folkerts; Joris Kloek; R B R Muijsers; Frans P Nijkamp
Reactive nitrogen and oxygen species in airway inflammation.
European journal of pharmacology 2001;429(1-3):251-62.
2001: R B R Muijsers; Nick H T Ten Hacken; Ingrid van Ark; Gert Folkerts; Frans P Nijkamp; Dirkje S Postma
L-Arginine is not the limiting factor for nitric oxide synthesis by human alveolar macrophages in vitro.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(4):667-71.
2001: R B R Muijsers; Ingrid van Ark; Gert Folkerts; Andries Koster; Antoon J M Van Oosterhout; Dirkje S Postma; Frans P Nijkamp
Apocynin and 1400 W prevents airway hyperresponsiveness during allergic reactions in mice.
British journal of pharmacology 2001;134(2):434-40.
2001: Robert Ten Broeke; Gert Folkerts; Thea Leusink-Muis; HJ Van Der Linde; Matteo Villain; MK Manion; Fred De Clerck; J Edwin Blalock; Frans P Nijkamp
Calcium sensors as new therapeutic targets for airway hyperresponsiveness and asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1831-3.
2001: Gert Folkerts; Dicky van Heuven-Nolsen; Frans P Nijkamp
Bradykinin causes inhibition of methacholine-induced bronchoconstriction in vivo in mice.
Naunyn-Schmiedeberg's archives of pharmacology 2001;364(1):53-8.
2001: Gert Folkerts; Joris Kloek; P Geppetti; HJ Van Der Linde; Frans P Nijkamp
Factors that determine acetylcholine responsiveness of guinea pig tracheal tubes.
European journal of pharmacology 2001;420(2-3):151-7.
2000: Josephine Hjoberg; Gert Folkerts; S B van Gessel; Marieann Högman; Göran Hedenstierna; F P Nijkamp
Hyperosmolarity-induced relaxation and prostaglandin release in guinea pig trachea in vitro.
European journal of pharmacology 2000;398(2):303-7.
2000: R B R Muijsers; Edwin van den Worm; Gert Folkerts; CJ Beukelman; Andries Koster; Dirkje S Postma; Frans P Nijkamp
Apocynin inhibits peroxynitrite formation by murine macrophages.
British journal of pharmacology 2000;130(4):932-6.
2000: Gert Folkerts; J W Vlieger; Annick de Vries; S Faas; HJ Van Der Linde; Ferdi Engels; J C de Jong; F A Verheyen; Dicky van Heuven-Nolsen; Frans P Nijkamp
Virus- and bradykinin-induced airway hyperresponsiveness in guinea pigs.
American journal of respiratory and critical care medicine 2000;161(5):1666-71.
1999: A Leusink-Muis; Robert Ten Broeke; Gert Folkerts; Fred De Clerck; Frans P Nijkamp
Betamethasone prevents virus-induced airway inflammation but not airway hyperresponsiveness in guinea pigs.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29 Suppl 2():82-5.
1999: J Scheerens; Gert Folkerts; HJ Van Der Linde; P J Sterk; D M Conroy; T J Williams; Frans P Nijkamp
Eotaxin levels and eosinophils in guinea pig broncho-alveolar lavage fluid are increased at the onset of a viral respiratory infection.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29 Suppl 2():74-7.
1999: Marcello Trevisani; Fabien Schmidlin; Michele Tognetto; F P Nijkamp; Jean-Pierre Gies; Nelly Frossard; Silvia Amadesi; Gert Folkerts; Pierangelo Geppetti
Evidence for in vitro expression of B1 receptor in the mouse trachea and urinary bladder.
British journal of pharmacology 1999;126(6):1293-300.
1998: G Sadeghi-Hashjin; Gert Folkerts; P A J Henricks; R B R Muijsers; Frans P Nijkamp
Peroxynitrite in airway diseases.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28(12):1464-73.
1998: Costanza Emanueli; Fabio L M Ricciardolo; L Vergnani; C Bertrand; F Ricci; Nadia Manzoli; Gert Folkerts; F P Nijkamp; Pierangelo Geppetti
Characterization of the endothelin receptor subtype mediating epithelium-derived relaxant nitric oxide release from guinea-pig trachea.
British journal of pharmacology 1998;125(5):963-8.
1998: Gert Folkerts; W W Busse; Frans P Nijkamp; Ronald L Sorkness; J E Gern
Virus-induced airway hyperresponsiveness and asthma.
American journal of respiratory and critical care medicine 1998;157(6 Pt 1):1708-20.
1998: G Sadeghi-Hashjin; P A J Henricks; Gert Folkerts; TL Muis; J Garssen; Frans P Nijkamp
Role of the epithelial layer in the generation of superoxide anion by the guinea-pig isolated trachea.
Mediators of inflammation 1998;7(1):35-40.
1997: Aletta D Kraneveld; Gert Folkerts; Antoon J M Van Oosterhout; Frans P Nijkamp
Airway hyperresponsiveness: first eosinophils and then neuropeptides.
International journal of immunopharmacology 1997;19(9-10):517-27.
1997: R B R Muijsers; Gert Folkerts; P A J Henricks; G Sadeghi-Hashjin; Frans P Nijkamp
Peroxynitrite: a two-faced metabolite of nitric oxide.
Life sciences 1997;60(21):1833-45.
1996: G Sadeghi-Hashjin; P A J Henricks; Gert Folkerts; A K Verheyen; H J van der Linde; Frans P Nijkamp
Bovine tracheal responsiveness in vitro: role of the epithelium and nitric oxide.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(11):2286-93.
1996: G Sadeghi-Hashjin; Gert Folkerts; P A J Henricks; P G van de Loo; I E Dik; Frans P Nijkamp
Relaxation of guinea-pig trachea by sodium nitroprusside: cyclic GMP and nitric oxide not involved.
British journal of pharmacology 1996;118(3):466-70.
1996: G Sadeghi-Hashjin; Gert Folkerts; P A J Henricks; A K Verheyen; H J van der Linde; Ingrid van Ark; A Coene; Frans P Nijkamp
Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo.
American journal of respiratory and critical care medicine 1996;153(5):1697-701.
1996: G Sadeghi-Hashjin; Gert Folkerts; P A J Henricks; P G Van de Loo; H J Van der Linde; I E Dik; Frans P Nijkamp
Induction of guinea pig airway hyperresponsiveness by inactivation of guanylate cyclase.
European journal of pharmacology 1996;302(1-3):109-15.
1996: M Figini; Fabio L M Ricciardolo; P Javdan; F P Nijkamp; Costanza Emanueli; P Pradelles; Gert Folkerts; Pierangelo Geppetti
Evidence that epithelium-derived relaxing factor released by bradykinin in the guinea pig trachea is nitric oxide.
American journal of respiratory and critical care medicine 1996;153(3):918-23.
1995: Gert Folkerts; H Van der Linde; P G Van de Loo; Ferdi Engels; Frans P Nijkamp
Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition.
European journal of pharmacology 1995;285(2):R1-2.
1995: G S Hashjin; P A J Henricks; Gert Folkerts; Frans P Nijkamp
Preparation of bovine tracheal smooth muscle for in vitro pharmacological studies.
Journal of pharmacological and toxicological methods 1995;34(2):103-8.
1995: Gert Folkerts; H van der Linde; A K Verheyen; Frans P Nijkamp
Endogenous nitric oxide modulation of potassium-induced changes in guinea-pig airway tone.
British journal of pharmacology 1995;115(7):1194-8.
1995: A R Ladenius; Gert Folkerts; H J van der Linde; Frans P Nijkamp
Potentiation by viral respiratory infection of ovalbumin-induced guinea-pig tracheal hyperresponsiveness: role for tachykinins.
British journal of pharmacology 1995;115(6):1048-52.
1995: Gert Folkerts; Frans P Nijkamp
Virus-induced airway hyperresponsiveness. Role of inflammatory cells and mediators.
American journal of respiratory and critical care medicine 1995;151(5):1666-73; discussion 1673-4.
1995: Gert Folkerts; H J van der Linde; Frans P Nijkamp
Virus-induced airway hyperresponsiveness in guinea pigs is related to a deficiency in nitric oxide.
The Journal of clinical investigation 1995;95(1):26-30.
1995: Antoon J M Van Oosterhout; Ingrid van Ark; Gert Folkerts; H J van der Linde; HF Savelkoul; A K Verheyen; Frans P Nijkamp
Antibody to interleukin-5 inhibits virus-induced airway hyperresponsiveness to histamine in guinea pigs.
American journal of respiratory and critical care medicine 1995;151(1):177-83.
1994: Frans P Nijkamp; Gert Folkerts
Nitric oxide and bronchial reactivity.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1994;24(10):905-14.
1993: Frans P Nijkamp; H J van der Linde; Gert Folkerts
Nitric oxide synthesis inhibitors induce airway hyperresponsiveness in the guinea pig in vivo and in vitro. Role of the epithelium.
The American review of respiratory disease 1993;148(3):727-34.
1993: Gert Folkerts; H J van der Linde; C Omini; Frans P Nijkamp
Virus-induced airway inflammation and hyperresponsiveness in the guinea-pig is inhibited by levodropropizine.
Naunyn-Schmiedeberg's archives of pharmacology 1993;348(2):213-9.
1993: Gert Folkerts; A K Verheyen; G M Geuens; H F Folkerts; Frans P Nijkamp
Virus-induced changes in airway responsiveness, morphology, and histamine levels in guinea pigs.
The American review of respiratory disease 1993;147(6 Pt 1):1569-77.
1993: Gert Folkerts; F De Clerck; I Reijnart; P Span; Frans P Nijkamp
Virus-induced airway hyperresponsiveness in the guinea-pig: possible involvement of histamine and inflammatory cells.
British journal of pharmacology 1993;108(4):1083-93.
1992: Gert Folkerts; Betty C A M van Esch; M Janssen; Frans P Nijkamp
Virus-induced airway hyperresponsiveness in guinea pigs in vivo: study of broncho-alveolar cell number and activity.
European journal of pharmacology 1992;228(4):219-27.
1992: Gert Folkerts; A Verheyen; M Janssen; Frans P Nijkamp
Virus-induced airway hyperresponsiveness in the guinea pig can be transferred by bronchoalveolar cells.
The Journal of allergy and clinical immunology 1992;90(3 Pt 1):364-72.
1992: Gert Folkerts; A Verheyen; Frans P Nijkamp
Viral infection in guinea pigs induces a sustained non-specific airway hyperresponsiveness and morphological changes of the respiratory tract.
European journal of pharmacology 1992;228(2-3):121-30.
1990: Gert Folkerts; Frans P Nijkamp
Parainfluenza-3 infection of the guinea pig airways induces respiratory airway hyperreactivity in vitro.
Agents and actions 1990;30(1-2):261-3.
1990: Gert Folkerts; M Janssen; Frans P Nijkamp
Parainfluenza-3 induced hyperreactivity of the guinea pig trachea coincides with an increased number of bronchoalveolar cells.
British journal of clinical pharmacology 1990;30 Suppl 1():159S-161S.
1990: Gert Folkerts; Betty C A M van Esch; M Janssen; Frans P Nijkamp
Superoxide production by broncho-alveolar cells is diminished in parainfluenza-3 virus treated guinea pigs.
Agents and actions. Supplements 1990;31():139-42.
1989: Frans P Nijkamp; Gert Folkerts; J R Beetens; F De Clerck
Suppression of PAF-induced bronchoconstriction in the guinea-pig by oxatomide: mechanism of action.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(1):111-8.
1989: Gert Folkerts; Ferdi Engels; Frans P Nijkamp
Endotoxin-induced hyperreactivity of the guinea-pig isolated trachea coincides with decreased prostaglandin E2 production by the epithelial layer.
British journal of pharmacology 1989;96(2):388-94.
1989: Gert Folkerts; Ferdi Engels; Frans P Nijkamp
Respiratory airway hyperreactivity coincides with decreased epithelium-derived PGE2.
Agents and actions 1989;26(1-2):68-9.
1988: C Loesberg; Gert Folkerts; Frans P Nijkamp
Effects of dietary linoleic acid on beta-adrenergic responsiveness of the guinea pig respiratory system.
Prostaglandins, leukotrienes, and essential fatty acids 1988;34(2):127-34.
1988: Antoon J M Van Oosterhout; F M Woutersen-van Nijnanten; Gert Folkerts; Frans P Nijkamp
Effects of anterior hypothalamic lesions and sham-operations on bacterial endotoxin-induced non-specific airway hyperreactivity in vivo and in vitro.
British journal of pharmacology 1988;94(3):908-16.
1988: Gert Folkerts; P A J Henricks; P J Slootweg; Frans P Nijkamp
Endotoxin-induced inflammation and injury of the guinea pig respiratory airways cause bronchial hyporeactivity.
The American review of respiratory disease 1988;137(6):1441-8.
1988: Antoon J M Van Oosterhout; Gert Folkerts; G A Ten Have; Frans P Nijkamp
Involvement of the spleen in the endotoxin-induced deterioration of the respiratory airway and lymphocyte beta-adrenergic systems of the guinea pig.
European journal of pharmacology 1988;147(3):421-9.
1988: Gert Folkerts; P A J Henricks; Frans P Nijkamp
Inflammatory reactions in the respiratory airways of the guinea pig do not necessarily induce bronchial hyperreactivity.
Agents and actions 1988;23(1-2):94-6.
1988: Gert Folkerts; Frans P Nijkamp
Effect of arachidonic acid metabolites on intact and epithelium-denuded tracheal spirals of endotoxin-treated guinea pigs.
Agents and actions 1988;23(1-2):91-3.
1987: Ferdi Engels; Gert Folkerts; Dicky van Heuven-Nolsen; Frans P Nijkamp
Haemophilus influenzae-induced decreases in lung beta-adrenoceptor function and number coincide with decreases in spleen noradrenaline.
Naunyn-Schmiedeberg's archives of pharmacology 1987;336(3):274-9.
1986: C Loesberg; Gert Folkerts; F M Woutersen-van Nijnanten; Frans P Nijkamp
Effects of dietary poly-unsaturated fatty acids on the beta-adrenergic receptor reactivity in the guinea pig respiratory system.
Agents and actions 1986;19(5-6):359-60.
1986: Dicky van Heuven-Nolsen; Gert Folkerts; Dick J De Wildt; F P Nijkamp
The influence of Bordetella pertussis and its constituents on the beta-adrenergic receptor in the guinea pig respiratory system.
Life sciences 1986;38(8):677-85.
1983: Gert Folkerts; F P Nijkamp; Antoon J M Van Oosterhout
Induction in guinea-pigs of airway hyperreactivity and decreased lung beta-adrenoceptor number by 15-hydroperoxy-arachidonic acid.
British journal of pharmacology 1983;80(4):597-9.