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Steven Foord

Research Profile

Chemicals & Drugs

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Glycosylation

Anatomy

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Publications

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Andrew J Brown; Susan M Goldsworthy; Ashley A Barnes; Michelle M Eilert; Tcheang Lili; Dion Daniels; Alison I Muir; Mark J Wigglesworth; Ian J Kinghorn; Neil J Fraser; Nicholas B Pike; Jay C Strum; Klaudia Steplewski; Paul R Murdock; Julie C Holder; Fiona Marshall; Philip G Szekeres; Shelagh Wilson; Diane M Ignar; Steven M Foord; Alan Wise; Simon J Dowell
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
Alan Wise; Steven M Foord; Neil J Fraser; Ashley A Barnes; Nabil A Elshourbagy; Michelle M Eilert; Diane M Ignar; Paul R Murdock; Klaudia Steplewski; Andrew Green; Andrew J Brown; Simon J Dowell; Philip G Szekeres; David G Hassall; Fiona Marshall; Shelagh Wilson; Nicholas B Pike
Molecular identification of high and low affinity receptors for nicotinic acid.
David R Poyner; Patrick M Sexton; Ian Marshall; David M Smith; Rémi Quirion; Walter Born; Roman Muff; Jan A Fischer; Steven M Foord
International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors.

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All Publications

2003: Andrew J Brown; Susan M Goldsworthy; Ashley A Barnes; Michelle M Eilert; Tcheang Lili; Dion Daniels; Alison I Muir; Mark J Wigglesworth; Ian J Kinghorn; Neil J Fraser; Nicholas B Pike; Jay C Strum; Klaudia Steplewski; Paul R Murdock; Julie C Holder; Fiona Marshall; Philip G Szekeres; Shelagh Wilson; Diane M Ignar; Steven M Foord; Alan Wise; Simon J Dowell
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
The Journal of biological chemistry 2003;278(13):11312-9.
2003: Alan Wise; Steven M Foord; Neil J Fraser; Ashley A Barnes; Nabil A Elshourbagy; Michelle M Eilert; Diane M Ignar; Paul R Murdock; Klaudia Steplewski; Andrew Green; Andrew J Brown; Simon J Dowell; Philip G Szekeres; David G Hassall; Fiona Marshall; Shelagh Wilson; Nicholas B Pike
Molecular identification of high and low affinity receptors for nicotinic acid.
The Journal of biological chemistry 2003;278(11):9869-74.
2002: David R Poyner; Patrick M Sexton; Ian Marshall; David M Smith; Rémi Quirion; Walter Born; Roman Muff; Jan A Fischer; Steven M Foord
International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors.
Pharmacological reviews 2002;54(2):233-46.
2001: S Hilairet; C Bélanger; Johanne Bertrand; André Laperrière; Steven M Foord; Michel Bouvier
Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin.
The Journal of biological chemistry 2001;276(45):42182-90.
2001: S Hilairet; Steven M Foord; Fiona Marshall; Michel Bouvier
Protein-protein interaction and not glycosylation determines the binding selectivity of heterodimers between the calcitonin receptor-like receptor and the receptor activity-modifying proteins.
The Journal of biological chemistry 2001;276(31):29575-81.
2000: Nanda Tilakaratne; George Christopoulos; E T Zumpe; Steven M Foord; Patrick M Sexton
Amylin receptor phenotypes derived from human calcitonin receptor/RAMP coexpression exhibit pharmacological differences dependent on receptor isoform and host cell environment.
The Journal of pharmacology and experimental therapeutics 2000;294(1):61-72.
2000: E T Zumpe; Nanda Tilakaratne; Neil J Fraser; George Christopoulos; Steven M Foord; Patrick M Sexton
Multiple ramp domains are required for generation of amylin receptor phenotype from the calcitonin receptor gene product.
Biochemical and biophysical research communications 2000;267(1):368-72.
1999: Steven M Foord; Alan Wise; J Brown; MJ Main; Neil J Fraser
The N-terminus of RAMPs is a critical determinant of the glycosylation state and ligand binding of calcitonin receptor-like receptor.
Biochemical Society transactions 1999;27(4):535-9.
1999: George Christopoulos; KJ Perry; Maria Morfis; Nanda Tilakaratne; Y Gao; Neil J Fraser; MJ Main; Steven M Foord; Patrick M Sexton
Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product.
Molecular pharmacology 1999;56(1):235-42.
1999: Neil J Fraser; Alan Wise; J Brown; L M McLatchie; MJ Main; Steven M Foord
The amino terminus of receptor activity modifying proteins is a critical determinant of glycosylation state and ligand binding of calcitonin receptor-like receptor.
Molecular pharmacology 1999;55(6):1054-9.
1999: Steven M Foord; Fiona Marshall
RAMPs: accessory proteins for seven transmembrane domain receptors.
Trends in pharmacological sciences 1999;20(5):184-7.
1998: Roman Muff; Kerstin Leuthäuser; N Bühlmann; Steven M Foord; Jan A Fischer; Walter Born
Receptor activity modifying proteins regulate the activity of a calcitonin gene-related peptide receptor in rabbit aortic endothelial cells.
FEBS letters 1998;441(3):366-8.
1998: Julia H White; Alan Wise; MJ Main; Andrew Green; Neil J Fraser; G H Disney; Ashley A Barnes; Piers C Emson; Steven M Foord; Fiona Marshall
Heterodimerization is required for the formation of a functional GABA(B) receptor.
Nature 1998;396(6712):679-82.
1998: MJ Main; J Brown; S Brown; Neil J Fraser; Steven M Foord
The CGRP receptor can couple via pertussis toxin sensitive and insensitive G proteins.
FEBS letters 1998;441(1):6-10.
1998: L M McLatchie; Neil J Fraser; MJ Main; Alan Wise; J Brown; N Thompson; R Solari; M G Lee; Steven M Foord
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.
Nature 1998;393(6683):333-9.
1997: Fiona Marshall; K Patel; K Lundstrom; J Camacho; Steven M Foord; M G Lee
Characterization of [3H]-prostaglandin E2 binding to prostaglandin EP4 receptors expressed with Semliki Forest virus.
British journal of pharmacology 1997;121(8):1673-8.
1996: Steven M Foord; B Marks; M Stolz; Emmanuel Bufflier; Neil J Fraser; M G Lee
The structure of the prostaglandin EP4 receptor gene and related pseudogenes.
Genomics 1996;35(1):182-8.