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Robert Forbes

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Protein Denaturation

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Wendy L Hulse; Jason Gray; Robert T Forbes
A discriminatory intrinsic dissolution study using UV area imaging analysis to gain additional insights into the dissolution behaviour of active pharmaceutical ingredients.
Wendy L Hulse; Robert T Forbes
A nanolitre method to determine the hydrodynamic radius of proteins and small molecules by Taylor dispersion analysis.
Wendy L Hulse; Robert T Forbes; Michael C Bonner; Matthias Getrost
Influence of protein on mannitol polymorphic form produced during co-spray drying.

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All Publications

2012: Wendy L Hulse; Jason Gray; Robert T Forbes
A discriminatory intrinsic dissolution study using UV area imaging analysis to gain additional insights into the dissolution behaviour of active pharmaceutical ingredients.
International journal of pharmaceutics 2012;434(1-2):133-9.
2011: Wendy L Hulse; Robert T Forbes
A nanolitre method to determine the hydrodynamic radius of proteins and small molecules by Taylor dispersion analysis.
International journal of pharmaceutics 2011;411(1-2):64-8.
2009: Wendy L Hulse; Robert T Forbes; Michael C Bonner; Matthias Getrost
Influence of protein on mannitol polymorphic form produced during co-spray drying.
International journal of pharmaceutics 2009;382(1-2):67-72.
2009: Wendy L Hulse; Robert T Forbes; Michael C Bonner; Matthias Getrost
The characterization and comparison of spray-dried mannitol samples.
Drug development and industrial pharmacy 2009;35(6):712-8.
2008: Wendy L Hulse; Robert T Forbes; Michael C Bonner; Matthias Getrost
Do co-spray dried excipients offer better lysozyme stabilisation than single excipients?
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;33(3):294-305.
2008: Amal A Elkordy; Robert T Forbes; Brian W Barry
Study of protein conformational stability and integrity using calorimetry and FT-Raman spectroscopy correlated with enzymatic activity.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;33(2):177-90.
2007: Robert T Forbes; Brian W Barry; Amal A Elkordy
Preparation and characterisation of spray-dried and crystallised trypsin: FT-Raman study to detect protein denaturation after thermal stress.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;30(3-4):315-23.
2006: V Chikhalia; Robert T Forbes; R A Storey; M Ticehurst
The effect of crystal morphology and mill type on milling induced crystal disorder.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;27(1):19-26.
2005: Adrian C Williams; Peter Timmins; Mingchu Lu; Robert T Forbes
Disorder and dissolution enhancement: deposition of ibuprofen on to insoluble polymers.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;26(3-4):288-94.
2004: Amal A Elkordy; Robert T Forbes; Brian W Barry
Stability of crystallised and spray-dried lysozyme.
International journal of pharmaceutics 2004;278(2):209-19.
2003: Tomohiro Yoshinari; Robert T Forbes; Peter York; Yoshiaki Kawashima
The improved compaction properties of mannitol after a moisture-induced polymorphic transition.
International journal of pharmaceutics 2003;258(1-2):121-31.
2003: Tomohiro Yoshinari; Robert T Forbes; Peter York; Yoshiaki Kawashima
Crystallisation of amorphous mannitol is retarded using boric acid.
International journal of pharmaceutics 2003;258(1-2):109-20.
2003: Saeed Moshashaée; Mikael Bisrat; Robert T Forbes; Eilís A Quinn; Håkan Nyqvist; Peter York
Supercritical fluid processing of proteins: lysozyme precipitation from aqueous solution.
The Journal of pharmacy and pharmacology 2003;55(2):185-92.
2002: Amal A Elkordy; Robert T Forbes; Brian W Barry
Integrity of crystalline lysozyme exceeds that of a spray-dried form.
International journal of pharmaceutics 2002;247(1-2):79-90.
2002: Tomohiro Yoshinari; Robert T Forbes; Peter York; Yoshiaki Kawashima
Moisture induced polymorphic transition of mannitol and its morphological transformation.
International journal of pharmaceutics 2002;247(1-2):69-77.
2001: A D Edwards; Boris Y Shekunov; A Kordikowski; Robert T Forbes; Peter York
Crystallization of pure anhydrous polymorphs of carbamazepine by solution enhanced dispersion with supercritical fluids (SEDS).
Journal of pharmaceutical sciences 2001;90(8):1115-24.
2001: A D Edwards; Boris Y Shekunov; Robert T Forbes; J Günter Grossmann; Peter York
Time-resolved X-ray scattering using synchrotron radiation applied to the study of a polymorphic transition in carbamazepine.
Journal of pharmaceutical sciences 2001;90(8):1106-14.
2000: KJ Crowley; Robert T Forbes; Peter York; Håkan Nyqvist; O Camber
Drug-fatty acid salt with wax-like properties employed as binder in melt granulation.
International journal of pharmaceutics 2000;211(1-2):9-17.
2000: KJ Crowley; Robert T Forbes; Peter York; D C Apperley; Håkan Nyqvist; O Camber
Characterization of oleic acid and propranolol oleate mesomorphism using (13)C solid-state nuclear magnetic resonance spectroscopy (SSNMR).
Journal of pharmaceutical sciences 2000;89(10):1286-95.
2000: S Moshashaée; Mikael Bisrat; Robert T Forbes; Håkan Nyqvist; Peter York
Supercritical fluid processing of proteins. I: lysozyme precipitation from organic solution.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;11(3):239-45.
1999: E A Quinn; Robert T Forbes; Adrian C Williams; M J Oliver; L McKenzie; T S Purewal
Protein conformational stability in the hydrofluoroalkane propellants tetrafluoroethane and heptafluoropropane analysed by Fourier transform Raman spectroscopy.
International journal of pharmaceutics 1999;186(1):31-41.
1999: S Branchu; Robert T Forbes; Peter York; S Petrén; Håkan Nyqvist; O Camber
Hydroxypropyl-beta-cyclodextrin inhibits spray-drying-induced inactivation of beta-galactosidase.
Journal of pharmaceutical sciences 1999;88(9):905-11.
1999: KJ Crowley; Robert T Forbes; Peter York; Håkan Nyqvist; O Camber
Oleate salt formation and mesomorphic behavior in the propranolol/oleic acid binary system.
Journal of pharmaceutical sciences 1999;88(6):586-91.
1999: S Branchu; Robert T Forbes; Peter York; Håkan Nyqvist
A central composite design to investigate the thermal stabilization of lysozyme.
Pharmaceutical research 1999;16(5):702-8.
1998: Robert T Forbes; K G Davis; M Hindle; J G Clarke; J Maas
Water vapor sorption studies on the physical stability of a series of spray-dried protein/sugar powders for inhalation.
Journal of pharmaceutical sciences 1998;87(11):1316-21.
1992: Robert T Forbes; Peter York; V Fawcett; L Shields
Physicochemical properties of salts of p-aminosalicylic acid. I. Correlation of crystal structure and hydrate stability.
Pharmaceutical research 1992;9(11):1428-35.