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Guido Forni

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Laura Conti; Guido Forni; Manuela Iezzi; Stefania Lanzardo; Alessandro Maiocchi; Monica Montone; Elisabetta Bolli; Chiara Brioschi; Federica Cavallo
Optical imaging detection of microscopic mammary cancer in ErbB-2 transgenic mice through the DA364 probe binding αv β3 integrins.
Stefania Lanzardo; Alessandro Maiocchi; Federico Maisano; Leonardo Manzoni; Daniela Arosio; Maria Paola Bartolomeo; Laura Belvisi; Chiara Brioschi; Laura Conti; Guido Forni
A new optical imaging probe targeting αVβ3 integrin in glioblastoma xenografts.
Graziella Berta; Susanna Cappia; Federica Di Scipio; Guido Forni; Manuela Iezzi; Barbara Mognetti; Piero Musiani; Mauro Papotti; Paolina Salamone; Michela Spadaro; Andrea E Sprio; Federica Cavallo
A DNA vaccine against ERBB2 impairs chemical carcinogenesis in random-bred hamsters.

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2013: Laura Conti; Guido Forni; Manuela Iezzi; Stefania Lanzardo; Alessandro Maiocchi; Monica Montone; Elisabetta Bolli; Chiara Brioschi; Federica Cavallo
Optical imaging detection of microscopic mammary cancer in ErbB-2 transgenic mice through the DA364 probe binding αv β3 integrins.
Contrast media & molecular imaging 2013;8(4):350-60.
2011: Stefania Lanzardo; Alessandro Maiocchi; Federico Maisano; Leonardo Manzoni; Daniela Arosio; Maria Paola Bartolomeo; Laura Belvisi; Chiara Brioschi; Laura Conti; Guido Forni
A new optical imaging probe targeting αVβ3 integrin in glioblastoma xenografts.
Contrast media & molecular imaging 2011;6(6):449-58.
2011: Graziella Berta; Susanna Cappia; Federica Di Scipio; Guido Forni; Manuela Iezzi; Barbara Mognetti; Piero Musiani; Mauro Papotti; Paolina Salamone; Michela Spadaro; Andrea E Sprio; Federica Cavallo
A DNA vaccine against ERBB2 impairs chemical carcinogenesis in random-bred hamsters.
Cancer prevention research (Philadelphia, Pa.) 2011;4(7):994-1001.
2011: Federica Cavallo; Carla De Giovanni; Patrizia Nanni; Guido Forni; Pier-Luigi Lollini
2011: the immune hallmarks of cancer.
Cancer immunology, immunotherapy : CII 2011;60(3):319-26.
2010: Marta Coscia; Elena Quaglino; Manuela Iezzi; Claudia Curcio; Francesca Pantaleoni; Chiara Riganti; Ingunn Holen; Hannu Mönkkönen; Mario Boccadoro; Guido Forni; Piero Musiani; Amalia Bosia; Federica Cavallo; Massimo Massaia
Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway.
Journal of cellular and molecular medicine 2010;14(12):2803-15.
2010: Sara Cabodi; Agata Tinnirello; Brigitte Bisaro; Giusy Tornillo; Maria del Pilar Camacho-Leal; Guido Forni; Rodica Cojoca; Manuela Iezzi; Augusto Amici; Maura Montani; Alessandra Eva; Paola Di Stefano; Senthil K Muthuswamy; Guido Tarone; Emilia Turco; Paola Defilippi
p130Cas is an essential transducer element in ErbB2 transformation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(10):3796-808.
2010: Simona Rolla; Francesco Ria; Sergio Occhipinti; Gabriele Di Sante; Manuela Iezzi; Michela Spadaro; Chiara Nicolò; Elena Ambrosino; Irene Fiore Merighi; Piero Musiani; Guido Forni; Federica Cavallo
Erbb2 DNA vaccine combined with regulatory T cell deletion enhances antibody response and reveals latent low-avidity T cells: potential and limits of its therapeutic efficacy.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(11):6124-32.
2010: Alessandra Porzia; Stefania Lanzardo; Arianna Citti; Federica Cavallo; Guido Forni; Angela Santoni; Ricciarda Galandrini; Rossella Paolini
Attenuation of PI3K/Akt-mediated tumorigenic signals through PTEN activation by DNA vaccine-induced anti-ErbB2 antibodies.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(8):4170-7.
2010: Elena Quaglino; Cristina Mastini; Augusto Amici; Cristina Marchini; Manuela Iezzi; Stefania Lanzardo; Carla De Giovanni; Maura Montani; Pier-Luigi Lollini; Giuseppe Masucci; Guido Forni; Federica Cavallo
A better immune reaction to Erbb-2 tumors is elicited in mice by DNA vaccines encoding rat/human chimeric proteins.
Cancer research 2010;70(7):2604-12.
2010: Jason C Steel; Charmaine A Ramlogan; Ping Yu; Yoshio Sakai; Guido Forni; Thomas A Waldmann; John C Morris
Interleukin-15 and its receptor augment dendritic cell vaccination against the neu oncogene through the induction of antibodies partially independent of CD4 help.
Cancer research 2010;70(3):1072-81.
2010: Isaia Barbieri; Elena Quaglino; Diego Maritano; Tania Pannellini; LUDOVICA RIERA; Federica Cavallo; Guido Forni; Piero Musiani; Roberto Chiarle; Valeria Poli
Stat3 is required for anchorage-independent growth and metastasis but not for mammary tumor development downstream of the ErbB-2 oncogene.
Molecular carcinogenesis 2010;49(2):114-20.
2009: Federica Cavallo; Guido Forni
Recent advances in cancer immunotherapy with an emphasis on vaccines.
Expert review of vaccines 2009;8(1):25-8.
2009: Kalle Andreasson; Karin Tegerstedt; Mathilda Eriksson; Claudia Curcio; Federica Cavallo; Guido Forni; Tina Dalianis; Torbjörn Ramqvist
Murine pneumotropic virus chimeric Her2/neu virus-like particles as prophylactic and therapeutic vaccines against Her2/neu expressing tumors.
International journal of cancer. Journal international du cancer 2009;124(1):150-6.
2008: Raffaele A Calogero; Elena Quaglino; Silvia Saviozzi; Guido Forni; Federica Cavallo
Oncoantigens as anti-tumor vaccination targets: the chance of a lucky strike?
Cancer immunology, immunotherapy : CII 2008;57(11):1685-94.
2008: Cristiana Caorsi; Paola Cappello; Paola Ceruti; Augusto Amici; C Marchini; Francesco Novelli; Guido Forni; Mirella Giovarelli
CCL16 enhances the CD8+ and CD4+ T cell reactivity to human HER-2 elicited by dendritic cells loaded with rat ortholog HER-2.
International journal of immunopathology and pharmacology 2008;21(4):867-77.
2008: Elena Quaglino; Cristina Mastini; Guido Forni; Federica Cavallo
ErbB2 transgenic mice: a tool for investigation of the immune prevention and treatment of mammary carcinomas.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2008;Chapter 20():Unit 20.9.1-20.9-10.
2008: Michela Spadaro; Cristiana Caorsi; Patrizia Ceruti; Atul Varadhachary; Guido Forni; Federica Pericle; Mirella Giovarelli
Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(8):2747-57.
2008: Roberto Chiarle; Cinzia Martinengo; Cristina Mastini; Chiara Ambrogio; Valentina D'Escamard; Guido Forni; Giorgio Inghirami
The anaplastic lymphoma kinase is an effective oncoantigen for lymphoma vaccination.
Nature medicine 2008;14(6):676-80.
2008: Cristina Mastini; Pablo Daniel Becker; Manuela Iezzi; Claudia Curcio; Piero Musiani; Guido Forni; Federica Cavallo; Carlos A Guzmán
Intramammary application of non-methylated-CpG oligodeoxynucleotides (CpG) inhibits both local and systemic mammary carcinogenesis in female BALB/c Her-2/neu transgenic mice.
Current cancer drug targets 2008;8(3):230-42.
2008: Simona Rolla; Cristina Marchini; Silvia Malinarich; Elena Quaglino; Stefania Lanzardo; Maura Montani; Manuela Iezzi; Mauro Angeletti; Giorgio Ramadori; Guido Forni; Federica Cavallo; Augusto Amici
Protective immunity against neu-positive carcinomas elicited by electroporation of plasmids encoding decreasing fragments of rat neu extracellular domain.
Human gene therapy 2008;19(3):229-40.
2008: Claudia Curcio; A S Khan; Augusto Amici; Michela Spadaro; Elena Quaglino; Federica Cavallo; Guido Forni; R Draghia-Akli
DNA immunization using constant-current electroporation affords long-term protection from autochthonous mammary carcinomas in cancer-prone transgenic mice.
Cancer gene therapy 2008;15(2):108-14.
2008: Elisa Ciraolo; Manuela Iezzi; Romina Marone; Stefano Marengo; Claudia Curcio; Carlotta Costa; Ornella Azzolino; Cristiano Gonella; Cristina Rubinetto; Haiyan Wu; Walter Dastrù; Erica L Martin; Lorenzo Silengo; Fiorella Altruda; Emilia Turco; Letizia Lanzetti; Piero Musiani; Thomas Rückle; Christian Rommel; Jonathan M Backer; Guido Forni; Matthias P Wymann; Emilio Hirsch
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development.
Science signaling 2008;1(36):ra3.
2007: Federica Cavallo; Raffaele Adolfo Calogero; Guido Forni
Are oncoantigens suitable targets for anti-tumour therapy?
Nature reviews. Cancer 2007;7(9):707-13.
2007: Michela Spadaro; Claudia Curcio; Atul Varadhachary; Federica Cavallo; Jose Engelmayer; Paul Blezinger; Federica Pericle; Guido Forni
Requirement for IFN-gamma, CD8+ T lymphocytes, and NKT cells in talactoferrin-induced inhibition of neu+ tumors.
Cancer research 2007;67(13):6425-32.
2007: Paola Di Stefano; Laura Damiano; Sara Cabodi; Simona Aramu; Luca Tordella; Alice Praduroux; Roberto Piva; Federica Cavallo; Guido Forni; Lorenzo Silengo; Guido Tarone; Emilia Turco; Paola Defilippi
p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity.
The EMBO journal 2007;26(12):2843-55.
2007: Laura Masuelli; Chiara Focaccetti; Vittore Cereda; Florigio Lista; Domenico Vitolo; Paola Trono; Pasquale Gallo; Augusto Amici; Paolo MONACI; Maurizio Mattei; Mauro Modesti; Guido Forni; Matthias H Kraus; Raffaella Muraro; Andrea Modesti; Roberto Bei
Gene-specific inhibition of breast carcinoma in BALB-neuT mice by active immunization with rat Neu or human ErbB receptors.
International journal of oncology 2007;30(2):381-92.
2007: Raffaele A Calogero; Francesca Cordero; Guido Forni; Federica Cavallo
Inflammation and breast cancer. Inflammatory component of mammary carcinogenesis in ErbB2 transgenic mice.
Breast cancer research : BCR 2007;9(4):211.
2007: Claudia Curcio; Tania Pannellini; Stefania Lanzardo; Guido Forni; Piero Musiani; Inés M Antón
WIP null mice display a progressive immunological disorder that resembles Wiskott-Aldrich syndrome.
The Journal of pathology 2007;211(1):67-75.
2007: Stefania Lanzardo; Claudia Curcio; Guido Forni; Inés M Antón
A role for WASP Interacting Protein, WIP, in fibroblast adhesion, spreading and migration.
The international journal of biochemistry & cell biology 2007;39(1):262-74.
2006: Simona Rolla; Chiara Nicoló; Silvia Malinarich; Massimiliano Orsini; Guido Forni; Federica Cavallo; Francesco Ria
Distinct and non-overlapping T cell receptor repertoires expanded by DNA vaccination in wild-type and HER-2 transgenic BALB/c mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(11):7626-33.
2006: Simonetta Geninatti Crich; Claudia Cabella; Alessandro Barge; Simona Belfiore; Cristina Ghirelli; Luciano Lattuada; Stefania Lanzardo; Armando Mortillaro; Lorenzo Tei; Massimo Visigalli; Guido Forni; Silvio Aime
In vitro and in vivo magnetic resonance detection of tumor cells by targeting glutamine transporters with Gd-based probes.
Journal of medicinal chemistry 2006;49(16):4926-36.
2006: Elena Ambrosino; Michela Spadaro; Manuela Iezzi; Claudia Curcio; Guido Forni; Piero Musiani; Wei-Zen Wei; Federica Cavallo
Immunosurveillance of Erbb2 carcinogenesis in transgenic mice is concealed by a dominant regulatory T-cell self-tolerance.
Cancer research 2006;66(15):7734-40.
2006: Tania Pannellini; Michela Spadaro; Emma Di Carlo; Elena Ambrosino; Manuela Iezzi; Augusto Amici; Pier-Luigi Lollini; Guido Forni; Federica Cavallo; Piero Musiani
Timely DNA vaccine combined with systemic IL-12 prevents parotid carcinomas before a dominant-negative p53 makes their growth independent of HER-2/neu expression.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7695-703.
2006: Lars Holmgren; Elena Ambrosino; Olivier Birot; Carl Tullus; Niina Veitonmäki; Tetyana Levchenko; Lena-Maria Carlson; Piero Musiani; Manuela Iezzi; Claudia Curcio; Guido Forni; Federica Cavallo; Rolf Kiessling
A DNA vaccine targeting angiomotin inhibits angiogenesis and suppresses tumor growth.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9208-13.
2006: Sara Cabodi; Agata Tinnirello; Paola Di Stefano; Brigitte Bisarò; Elena Ambrosino; Isabella Castellano; Anna Sapino; RICCARDO ARISIO; Federica Cavallo; Guido Forni; Marina Glukhova; Lorenzo Silengo; Fiorella Altruda; Emilia Turco; Guido Tarone; Paola Defilippi
p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.
Cancer research 2006;66(9):4672-80.
2006: Pier-Luigi Lollini; Federica Cavallo; Patrizia Nanni; Guido Forni
Vaccines for tumour prevention.
Nature reviews. Cancer 2006;6(3):204-16.
2006: Federica Cavallo; Rienk Offringa; Sjoerd H van der burg; Guido Forni; Cornelis J M Melief
Vaccination for treatment and prevention of cancer in animal models.
Advances in immunology 2006;90():175-213.
2005: Federica Cavallo; Annalisa Astolfi; Manuela Iezzi; Francesca Cordero; Pier-Luigi Lollini; Guido Forni; Raffaele A Calogero
An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer immunological prevention.
BMC bioinformatics 2005;6 Suppl 4():S7.
2005: Graziella Berta; Barbara Mognetti; Michela Spadaro; E Trione; Augusto Amici; Guido Forni; Francesco Di Carlo; Federica Cavallo
Anti-HER-2 DNA vaccine protects Syrian hamsters against squamous cell carcinomas.
British journal of cancer 2005;93(11):1250-6.
2005: Karin Tegerstedt; Jan Alvar Lindencrona; Claudia Curcio; Kalle Andreasson; Carl Tullus; Guido Forni; Tina Dalianis; Rolf Kiessling; Torbjörn Ramqvist
A single vaccination with polyomavirus VP1/VP2Her2 virus-like particles prevents outgrowth of HER-2/neu-expressing tumors.
Cancer research 2005;65(13):5953-7.
2005: Annalisa Astolfi; Simona Rolla; Patrizia Nanni; Elena Quaglino; Carla De Giovanni; Manuela Iezzi; Piero Musiani; Guido Forni; Pier-Luigi Lollini; Federica Cavallo; Raffaele A Calogero
Immune prevention of mammary carcinogenesis in HER-2/neu transgenic mice: a microarray scenario.
Cancer immunology, immunotherapy : CII 2005;54(6):599-610.
2005: Elena Quaglino; Cristina Mastini; Manuela Iezzi; Guido Forni; Piero Musiani; Leah N Klapper; Britta Hardy; Federica Cavallo
The adjuvant activity of BAT antibody enables DNA vaccination to inhibit the progression of established autochthonous Her-2/neu carcinomas in BALB/c mice.
Vaccine 2005;23(25):3280-7.
2005: Marco Lo Iacono; Federica Cavallo; Elena Quaglino; Simona Rolla; Manuela Iezzi; Serenella M Pupa; Carla De Giovanni; Pier-Luigi Lollini; Piero Musiani; Guido Forni; Raffaele A Calogero
A limited autoimmunity to p185neu elicited by DNA and allogeneic cell vaccine hampers the progression of preneoplastic lesions in HER-2/NEU transgenic mice.
International journal of immunopathology and pharmacology 2005;18(2):351-63.
2005: Annalisa Astolfi; Lorena Landuzzi; Giordano Nicoletti; Carla De Giovanni; Stefania Croci; Arianna Palladini; Silvano Ferrini; Manuela Iezzi; Piero Musiani; Federica Cavallo; Guido Forni; Patrizia Nanni; Pier-Luigi Lollini
Gene expression analysis of immune-mediated arrest of tumorigenesis in a transgenic mouse model of HER-2/neu-positive basal-like mammary carcinoma.
The American journal of pathology 2005;166(4):1205-16.
2005: Michela Spadaro; Elena Ambrosino; Manuela Iezzi; Emma Di Carlo; Pamela Sacchetti; Claudia Curcio; Augusto Amici; Wei-Zen Wei; Piero Musiani; Pier-Luigi Lollini; Federica Cavallo; Guido Forni
Cure of mammary carcinomas in Her-2 transgenic mice through sequential stimulation of innate (neoadjuvant interleukin-12) and adaptive (DNA vaccine electroporation) immunity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(5):1941-52.
2005: Pier-Luigi Lollini; Carla De Giovanni; Tania Pannellini; Federica Cavallo; Guido Forni; Patrizia Nanni
Cancer immunoprevention.
Future oncology (London, England) 2005;1(1):57-66.
2005: Simonetta Geninatti Crich; Stefania Lanzardo; Alessandro Barge; Giovanna Esposito; Lorenzo Tei; Guido Forni; Silvio Aime
Visualization through magnetic resonance imaging of DNA internalized following "in vivo" electroporation.
Molecular imaging 2005;4(1):7-17.
2005: Emma Di Carlo; Paola Cappello; Carlo Sorrentino; Tommaso D'Antuono; Antonella Pellicciotta; Mirella Giovarelli; Guido Forni; Piero Musiani; Fréderic Triebel
Immunological mechanisms elicited at the tumour site by lymphocyte activation gene-3 (LAG-3) versus IL-12: sharing a common Th1 anti-tumour immune pathway.
The Journal of pathology 2005;205(1):82-91.
2004: Stefania Croci; Giordano Nicoletti; Lorena Landuzzi; Carla De Giovanni; Annalisa Astolfi; Chiara Marini; Emma Di Carlo; Piero Musiani; Guido Forni; Patrizia Nanni; Pier-Luigi Lollini
Immunological prevention of a multigene cancer syndrome.
Cancer research 2004;64(22):8428-34.
2004: Atul Varadhachary; Jeffrey S Wolf; Karel Petrak; Bert W O'Malley; Michela Spadaro; Claudia Curcio; Guido Forni; Federica Pericle
Oral lactoferrin inhibits growth of established tumors and potentiates conventional chemotherapy.
International journal of cancer. Journal international du cancer 2004;111(3):398-403.
2004: Patrizia Nanni; Lorena Landuzzi; Giordano Nicoletti; Carla De Giovanni; Ilaria Rossi; Stefania Croci; Annalisa Astolfi; Manuela Iezzi; Emma Di Carlo; Piero Musiani; Guido Forni; Pier-Luigi Lollini
Immunoprevention of mammary carcinoma in HER-2/neu transgenic mice is IFN-gamma and B cell dependent.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2288-96.
2004: Raffaele A Calogero; Piero Musiani; Guido Forni; Federica Cavallo
Towards a long-lasting immune prevention of HER2 mammary carcinomas: directions from transgenic mice.
Cell cycle (Georgetown, Tex.) 2004;3(6):704-6.
2004: Elena Quaglino; Manuela Iezzi; Cristina Mastini; Augusto Amici; Federica Pericle; Emma Di Carlo; Serenella M Pupa; Carla De Giovanni; Michela Spadaro; Claudia Curcio; Pier-Luigi Lollini; Piero Musiani; Guido Forni; Federica Cavallo
Electroporated DNA vaccine clears away multifocal mammary carcinomas in her-2/neu transgenic mice.
Cancer research 2004;64(8):2858-64.
2004: Elena Quaglino; Simona Rolla; Manuela Iezzi; Michela Spadaro; Piero Musiani; Carla De Giovanni; Pier-Luigi Lollini; Stefania Lanzardo; Guido Forni; Remo Sanges; Stefania Crispi; Pasquale De Luca; Raffaele A Calogero; Federica Cavallo
Concordant morphologic and gene expression data show that a vaccine halts HER-2/neu preneoplastic lesions.
The Journal of clinical investigation 2004;113(5):709-17.
2004: Michela Spadaro; Stefania Lanzardo; Claudia Curcio; Guido Forni; Federica Cavallo
Immunological inhibition of carcinogenesis.
Cancer immunology, immunotherapy : CII 2004;53(3):204-16.
2004: Tania Pannellini; Guido Forni; Piero Musiani
Immunobiology of her-2/neu transgenic mice.
Breast disease 2004;20():33-42.
2004: Michela Spadaro; Guido Forni
Proinflammatory cytokines, immune response and tumour progression.
Novartis Foundation symposium 2004;256():92-9; discussion 99-111, 266-9.
2004: Paola Cappello; Cristiana Caorsi; Marita Bosticardo; Stefania De Angelis; Francesco Novelli; Guido Forni; Mirella Giovarelli
CCL16/LEC powerfully triggers effector and antigen-presenting functions of macrophages and enhances T cell cytotoxicity.
Journal of leukocyte biology 2004;75(1):135-42.
2003: Guido Forni; Claudia Curcio; Michela Spadaro; John Iliffe; Elena Quaglino; Emma Di Carlo; Piero Musiani; Pier-Luigi Lollini
Immunization in tumor prevention.
International immunopharmacology 2003;3(8):1151-8.
2003: Patrizia Nanni; Giordano Nicoletti; Carla De Giovanni; Lorena Landuzzi; Emma Di Carlo; Manuela Iezzi; Cinzia Ricci; Annalisa Astolfi; Stefania Croci; Francesco Marangoni; Piero Musiani; Guido Forni; Pier-Luigi Lollini
Prevention of HER-2/neu transgenic mammary carcinoma by tamoxifen plus interleukin 12.
International journal of cancer. Journal international du cancer 2003;105(3):384-9.
2003: Paola Cappello; Frederic Triebel; Manuela Iezzi; Cristiana Caorsi; Elena Quaglino; Pier-Luigi Lollini; Augusto Amici; Emma Di Carlo; Piero Musiani; Mirella Giovarelli; Guido Forni
LAG-3 enables DNA vaccination to persistently prevent mammary carcinogenesis in HER-2/neu transgenic BALB/c mice.
Cancer research 2003;63(10):2518-25.
2003: Claudia Curcio; Emma Di Carlo; Raphael Clynes; Mark J Smyth; Katia Boggio; Elena Quaglino; Michela Spadaro; Mario P Colombo; Augusto Amici; Pier-Luigi Lollini; Piero Musiani; Guido Forni
Nonredundant roles of antibody, cytokines, and perforin in the eradication of established Her-2/neu carcinomas.
The Journal of clinical investigation 2003;111(8):1161-70.
2003: Pier-Luigi Lollini; Guido Forni
Cancer immunoprevention: tracking down persistent tumor antigens.
Trends in immunology 2003;24(2):62-6.
2002: Pier-Luigi Lollini; Carla De Giovanni; Giordano Nicoletti; Emma Di Carlo; Piero Musiani; Patrizia Nanni; Guido Forni
Immunoprevention of colorectal cancer: a future possibility?
Gastroenterology clinics of North America 2002;31(4):1001-14.
2002: Giuliana Losana; Chiara Bovolenta; Laura Rigamonti; Igor Borghi; Frédéric Altare; Emmanuelle Jouanguy; Guido Forni; Jean-Laurent Casanova; Barbara Sherry; Manuela Mengozzi; Trinchieri Giorgio; Guido Poli; Franca Gerosa; Francesco Novelli
IFN-gamma and IL-12 differentially regulate CC-chemokine secretion and CCR5 expression in human T lymphocytes.
Journal of leukocyte biology 2002;72(4):735-42.
2002: Pier-Luigi Lollini; Guido Forni
Antitumor vaccines: is it possible to prevent a tumor?
Cancer immunology, immunotherapy : CII 2002;51(8):409-16.
2002: Antonella De Stefani; Guido Forni; Riccardo Ragona; Giovanni P Cavallo; Mario Bussi; Antonio Usai; Fausto Badellino; Giorgio Cortesina
Improved survival with perilymphatic interleukin 2 in patients with resectable squamous cell carcinoma of the oral cavity and oropharynx.
Cancer 2002;95(1):90-7.
2002: Giuliana Losana; Laura Rigamonti; Igor Borghi; Barbara Assenzio; Silvia Ariotti; Emmanuelle Jouanguy; Frédéric Altare; Guido Forni; Jean-Laurent Casanova; Francesco Novelli
Requirement for both IL-12 and IFN-gamma signaling pathways in optimal IFN-gamma production by human T cells.
European journal of immunology 2002;32(3):693-700.
2002: Elena Quaglino; Stefania Rovero; Federica Cavallo; Piero Musiani; Augusto Amici; Giordano Nicoletti; Patrizia Nanni; Guido Forni
Immunological prevention of spontaneous tumors: a new prospect?
Immunology letters 2002;80(2):75-9.
2002: Paola Cappello; Francesco Novelli; Guido Forni; Mirella Giovarelli
Death receptor ligands in tumors.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2002;25(1):1-15.
2001: Emma Di Carlo; Manuela Iezzi; Tania Pannellini; F Zaccardi; Andrea Modesti; Guido Forni; Piero Musiani
Neutrophils in anti-cancer immunological strategies: old players in new games.
Journal of hematotherapy & stem cell research 2001;10(6):739-48.
2001: Paola Bernabei; Eliana M Coccia; Laura Rigamonti; Marita Bosticardo; Guido Forni; Sidney Pestka; Christopher D Krause; Angela Battistini; Francesco Novelli
Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death.
Journal of leukocyte biology 2001;70(6):950-60.
2001: Patrizia Nanni; Giordano Nicoletti; Carla De Giovanni; Lorena Landuzzi; Emma Di Carlo; Federica Cavallo; Serenella M Pupa; Ilaria Rossi; Mario P Colombo; Cinzia Ricci; Annalisa Astolfi; Piero Musiani; Guido Forni; Pier-Luigi Lollini
Combined allogeneic tumor cell vaccination and systemic interleukin 12 prevents mammary carcinogenesis in HER-2/neu transgenic mice.
The Journal of experimental medicine 2001;194(9):1195-205.
2001: Carla De Giovanni; Giordano Nicoletti; Lorena Landuzzi; Ilaria Rossi; Annalisa Astolfi; Cinzia Ricci; E Di Carlo; Piero Musiani; Guido Forni; D Fradelizi; Patrizia Nanni; Pier-Luigi Lollini
Therapy of lung metastases through combined vaccination with carcinoma cells engineered to release IL-13 and IFN-gamma.
Gene therapy 2001;8(22):1698-704.
2001: F Gavallo; E Di Carlo; E Quaglin; M Jezzi; Marina Strasly; Federico Bussolino; Mario P Colombo; Patrizia Nanni; Pier-Luigi Lollini; Piero Musiani; Guido Forni
Prevention by delay: nonspecific immunity elicited by IL-12 hinders Her-2/neu mammary carcinogenesis in transgenic mice.
Journal of biological regulators and homeostatic agents 2001;15(4):351-8.
2001: Marita Bosticardo; Silvia Ariotti; Giuliana Losana; Paola Bernabei; Guido Forni; Francesco Novelli
Biased activation of human T lymphocytes due to low extracellular pH is antagonized by B7/CD28 costimulation.
European journal of immunology 2001;31(9):2829-38.
2001: Federica Cavallo; Elena Quaglino; L Cifaldi; Emma Di Carlo; A André; Paola Bernabei; Piero Musiani; Guido Forni; Raffaele A Calogero
Interleukin 12-activated lymphocytes influence tumor genetic programs.
Cancer research 2001;61(8):3518-23.
2001: L Cifaldi; Elena Quaglino; Emma Di Carlo; Piero Musiani; Michela Spadaro; Pier-Luigi Lollini; Stanley Wolf; Katia Boggio; Guido Forni; Federica Cavallo
A light, nontoxic interleukin 12 protocol inhibits HER-2/neu mammary carcinogenesis in BALB/c transgenic mice with established hyperplasia.
Cancer research 2001;61(7):2809-12.
2001: Marina Strasly; Federica Cavallo; Massimo Geuna; stefania mitola; Mario P Colombo; Guido Forni; Federico Bussolino
IL-12 inhibition of endothelial cell functions and angiogenesis depends on lymphocyte-endothelial cell cross-talk.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):3890-9.
2001: Stefania Rovero; Katia Boggio; E Di Carlo; Augusto Amici; Elena Quaglino; Paola Porcedda; Piero Musiani; Guido Forni
Insertion of the DNA for the 163-171 peptide of IL1beta enables a DNA vaccine encoding p185(neu) to inhibit mammary carcinogenesis in Her-2/neu transgenic BALB/c mice.
Gene therapy 2001;8(6):447-52.
2001: Emma Di Carlo; Stefania Rovero; Katia Boggio; Elena Quaglino; Augusto Amici; Arianna Smorlesi; Guido Forni; Piero Musiani
Inhibition of mammary carcinogenesis by systemic interleukin 12 or p185neu DNA vaccination in Her-2/neu transgenic BALB/c mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):830s-837s.
2001: Paola Bernabei; Attilio Allione; Laura Rigamonti; Marita Bosticardo; Giuliana Losana; Igor Borghi; Guido Forni; Francesco Novelli
Regulation of interferon-gamma receptor (INF-gammaR) chains: a peculiar way to rule the life and death of human lymphocytes.
European cytokine network 2001;12(1):6-14.
2001: Emma Di Carlo; Guido Forni; P Lollini; M P Colombo; Andrea Modesti; Piero Musiani
The intriguing role of polymorphonuclear neutrophils in antitumor reactions.
Blood 2001;97(2):339-45.
2000: MG Diodoro; Emma Di Carlo; R Zappacosta; Manuela Iezzi; Anna Coletti; Andrea Modesti; Tommaso D'Antuono; Guido Forni; Piero Musiani
Salivary carcinoma in HER-2/neu transgenic male mice: an angiogenic switch is not required for tumor onset and progression.
International journal of cancer. Journal international du cancer 2000;88(3):329-35.
2000: Stefania Rovero; Augusto Amici; E Di Carlo; Roberto Bei; Patrizia Nanni; Elena Quaglino; Paola Porcedda; Katia Boggio; Arianna Smorlesi; Pier-Luigi Lollini; Lorena Landuzzi; Mario P Colombo; Mirella Giovarelli; Piero Musiani; Guido Forni
DNA vaccination against rat her-2/Neu p185 more effectively inhibits carcinogenesis than transplantable carcinomas in transgenic BALB/c mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5133-42.
2000: Patrizia Nanni; Serenella M Pupa; Giordano Nicoletti; Carla De Giovanni; Lorena Landuzzi; Ilaria Rossi; Annalisa Astolfi; Cinzia Ricci; R De Vecchi; Annamaria Invernizzi; Emma Di Carlo; Piero Musiani; Guido Forni; S Menard; Pier-Luigi Lollini
p185(neu) protein is required for tumor and anchorage-independent growth, not for cell proliferation of transgenic mammary carcinoma.
International journal of cancer. Journal international du cancer 2000;87(2):186-94.
2000: Guido Forni; Pier-Luigi Lollini; Piero Musiani; Mario P Colombo
Immunoprevention of cancer: is the time ripe?
Cancer research 2000;60(10):2571-5.
2000: Mirella Giovarelli; Paola Cappello; Guido Forni; TW Salcedo; Paul Moore; D W LeFleur; Bernardetta Nardelli; E Di Carlo; Pier-Luigi Lollini; Steve Ruben; Stephen Ullrich; G Garotta; Piero Musiani
Tumor rejection and immune memory elicited by locally released LEC chemokine are associated with an impressive recruitment of APCs, lymphocytes, and granulocytes.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):3200-6.
2000: Katia Boggio; Emma Di Carlo; Stefania Rovero; Federica Cavallo; Elena Quaglino; Pier-Luigi Lollini; Patrizia Nanni; Giordano Nicoletti; Stanley Wolf; Piero Musiani; Guido Forni
Ability of systemic interleukin-12 to hamper progressive stages of mammary carcinogenesis in HER2/neu transgenic mice.
Cancer research 2000;60(2):359-64.
2000: Laura Rigamonti; Silvia Ariotti; Giuliana Losana; Roberto Gradini; M A Russo; Emmanuelle Jouanguy; Jean-Laurent Casanova; Guido Forni; Francesco Novelli
Surface expression of the IFN-gamma R2 chain is regulated by intracellular trafficking in human T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):201-7.
1999: Mirella Giovarelli; Piero Musiani; G Garotta; R Ebner; Emma Di Carlo; Y Kim; Paola Cappello; Laura Rigamonti; Paola Bernabei; Francesco Novelli; Andrea Modesti; Anna Coletti; A K Ferrie; Pier-Luigi Lollini; Steve Ruben; TW Salcedo; Guido Forni
A "stealth effect": adenocarcinoma cells engineered to express TRAIL elude tumor-specific and allogeneic T cell reactions.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):4886-93.
1999: Attilio Allione; Paola Bernabei; Marita Bosticardo; Silvia Ariotti; Guido Forni; Francesco Novelli
Nitric oxide suppresses human T lymphocyte proliferation through IFN-gamma-dependent and IFN-gamma-independent induction of apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(8):4182-91.
1999: Emma Di Carlo; MG Diodoro; Katia Boggio; Andrea Modesti; M Modesti; Patrizia Nanni; Guido Forni; Piero Musiani
Analysis of mammary carcinoma onset and progression in HER-2/neu oncogene transgenic mice reveals a lobular origin.
Laboratory investigation; a journal of technical methods and pathology 1999;79(10):1261-9.
1999: P Nanni; Guido Forni; P L Lollini
Cytokine gene therapy: hopes and pitfalls.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(3):261-6.
1999: Guido Forni; Katia Boggio
Cytokine gene-engineered vaccines.
Current opinion in molecular therapeutics 1999;1(1):34-8.
1999: M Milella; Jordan Jacobelli; F Cavallo; A Guarini; Francesca Velotti; Luigi Frati; R Foà; Guido Forni; Angela Santoni
Interleukin-2 gene transfer into human transitional cell carcinoma of the urinary bladder.
British journal of cancer 1999;79(5-6):770-9.
1999: Federica Cavallo; Emma Di Carlo; M Butera; R Verrua; Mario P Colombo; Piero Musiani; Guido Forni
Immune events associated with the cure of established tumors and spontaneous metastases by local and systemic interleukin 12.
Cancer research 1999;59(2):414-21.
1999: Francesco Novelli; Attilio Allione; Valerie Wells; Guido Forni; Livio Mallucci
Negative cell cycle control of human T cells by beta-galactoside binding protein (beta GBP): induction of programmed cell death in leukaemic cells.
Journal of cellular physiology 1999;178(1):102-8.
1998: Emma Di Carlo; Andrea Modesti; Anna Coletti; Mario P Colombo; Mirella Giovarelli; Guido Forni; MG Diodoro; Piero Musiani
Interaction between endothelial cells and the secreted cytokine drives the fate of an IL4- or an IL5-transduced tumour.
The Journal of pathology 1998;186(4):390-7.
1998: Attilio Allione; Valerie Wells; Guido Forni; Livio Mallucci; Francesco Novelli
Beta-galactoside-binding protein (beta GBP) alters the cell cycle, up-regulates expression of the alpha- and beta-chains of the IFN-gamma receptor, and triggers IFN-gamma-mediated apoptosis of activated human T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(5):2114-9.
1998: Katia Boggio; Giordano Nicoletti; Emma Di Carlo; Federica Cavallo; Lorena Landuzzi; Cecilia Melani; Mirella Giovarelli; Ilaria Rossi; Patrizia Nanni; Carla De Giovanni; P Bouchard; Stanley Wolf; Andrea Modesti; Piero Musiani; Pier-Luigi Lollini; Mario P Colombo; Guido Forni
Interleukin 12-mediated prevention of spontaneous mammary adenocarcinomas in two lines of Her-2/neu transgenic mice.
The Journal of experimental medicine 1998;188(3):589-96.
1998: Emma Di Carlo; Anna Coletti; Andrea Modesti; Mirella Giovarelli; Guido Forni; Piero Musiani
Local release of interleukin-10 by transfected mouse adenocarcinoma cells exhibits pro- and anti-inflammatory activity and results in a delayed tumor rejection.
European cytokine network 1998;9(1):61-8.
1998: Patrizia Nanni; Carla De Giovanni; Giordano Nicoletti; Lorena Landuzzi; Ilaria Rossi; Flavia Frabetti; Mirella Giovarelli; Guido Forni; Federica Cavallo; Emma Di Carlo; Piero Musiani; Pier-Luigi Lollini
The immune response elicited by mammary adenocarcinoma cells transduced with interferon-gamma and cytosine deaminase genes cures lung metastases by parental cells.
Human gene therapy 1998;9(2):217-24.
1997: Guido Forni; Katia Boggio; Mirella Giovarelli; Federica Cavallo
The dream of effective cytokine-based tumor vaccines.
European cytokine network 1997;8(3):324-5.
1997: Federica Cavallo; P Signorelli; Mirella Giovarelli; Piero Musiani; A Modesti; M J Brunda; Mario P Colombo; Guido Forni
Antitumor efficacy of adenocarcinoma cells engineered to produce interleukin 12 (IL-12) or other cytokines compared with exogenous IL-12.
Journal of the National Cancer Institute 1997;89(14):1049-58.
1997: Francesco Novelli; Mario Milco D'Elios; Paola Bernabei; L Ozmen; Laura Rigamonti; Fabio Almerigogna; Guido Forni; Gianfranco Del Prete
Expression and role in apoptosis of the alpha- and beta-chains of the IFN-gamma receptor on human Th1 and Th2 clones.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):206-13.
1997: Francesco Novelli; Attilio Allione; Paola Bernabei; Laura Rigamonti; Guido Forni
Antiblastic chemotherapy drugs up-modulate interferon-gamma receptor expression on human malignant T cells.
Cancer detection and prevention 1997;21(2):191-5.
1997: Susanna Scarpa; Anna Giuffrida; Camilla Palumbo; Fortunata Vasaturo; P Signorelli; Guido Forni; Mauro Modesti; Maria Ferrantini; Filippo Belardelli; Piero Musiani; Andrea Modesti
Extracellular matrix remodelling in a murine mammary adenocarcinoma transfected with the interferon-alpha 1 gene.
The Journal of pathology 1997;181(1):116-23.
1997: Piero Musiani; Andrea Modesti; Mirella Giovarelli; Federica Cavallo; Mario P Colombo; Pier-Luigi Lollini; Guido Forni
Cytokines, tumour-cell death and immunogenicity: a question of choice.
Immunology today 1997;18(1):32-6.
1996: Patrizia Nanni; Carla De Giovanni; Lorena Landuzzi; Giordano Nicoletti; Flavia Frabetti; Ilaria Rossi; Federica Cavallo; Mirella Giovarelli; Guido Forni; Pier-Luigi Lollini
Therapy of murine mammary carcinoma metastasis with interferon gamma and MHC gene-transduced tumour cells.
British journal of cancer 1996;74(10):1564-9.
1996: Francesco Novelli; Paola Bernabei; L Ozmen; Laura Rigamonti; Attilio Allione; S Pestka; G Garotta; Guido Forni
Switching on of the proliferation or apoptosis of activated human T lymphocytes by IFN-gamma is correlated with the differential expression of the alpha- and beta-chains of its receptor.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(5):1935-43.
1996: A Martin-Fontecha; Federica Cavallo; Matteo Bellone; S Heltai; Giandomenica Iezzi; P Tornaghi; N Nabavi; Guido Forni; Paolo Dellabona; Giulia Casorati
Heterogeneous effects of B7-1 and B7-2 in the induction of both protective and therapeutic anti-tumor immunity against different mouse tumors.
European journal of immunology 1996;26(8):1851-9.
1996: Antonella De Stefani; Guido Valente; Guido Forni; Walter LERDA; Riccardo Ragona; Giorgio Cortesina
Treatment of oral cavity and oropharynx squamous cell carcinoma with perilymphatic interleukin-2: clinical and pathologic correlations.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1996;19(2):125-33.
1996: Piero Musiani; Attilio Allione; Anna Modica; P L Lollini; M Giovarelli; Federica Cavallo; Filippo Belardelli; Guido Forni; Andrea Modesti
Role of neutrophils and lymphocytes in inhibition of a mouse mammary adenocarcinoma engineered to release IL-2, IL-4, IL-7, IL-10, IFN-alpha, IFN-gamma, and TNF-alpha.
Laboratory investigation; a journal of technical methods and pathology 1996;74(1):146-57.
1995: Guido Forni; Federica Cavallo; M Consalvo; Attilio Allione; Paolo Dellabona; Giulia Casorati; Mirella Giovarelli
Molecular approaches to cancer immunotherapy.
Cytokines and molecular therapy 1995;1(4):225-48.
1995: Pier-Luigi Lollini; Carla De Giovanni; Lorena Landuzzi; Giordano Nicoletti; Flavia Frabetti; Federica Cavallo; Mirella Giovarelli; Guido Forni; Anna Modica; Andrea Modesti
Transduction of genes coding for a histocompatibility (MHC) antigen and for its physiological inducer interferon-gamma in the same cell: efficient MHC expression and inhibition of tumor and metastasis growth.
Human gene therapy 1995;6(6):743-52.
1995: M Consalvo; Craig A Mullen; Andrea Modesti; Piero Musiani; Attilio Allione; Federica Cavallo; Mirella Giovarelli; Guido Forni
5-Fluorocytosine-induced eradication of murine adenocarcinomas engineered to express the cytosine deaminase suicide gene requires host immune competence and leaves an efficient memory.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(10):5302-12.
1995: Federica Cavallo; A Martin-Fontecha; Matteo Bellone; S Heltai; E Gatti; P Tornaghi; Massimo Freschi; Guido Forni; Paolo Dellabona; Giulia Casorati
Co-expression of B7-1 and ICAM-1 on tumors is required for rejection and the establishment of a memory response.
European journal of immunology 1995;25(5):1154-62.
1994: F Pericle; Mirella Giovarelli; Mario P Colombo; G Ferrari; Piero Musiani; Andrea Modesti; Federica Cavallo; F Di Pierro; Francesco Novelli; Guido Forni
An efficient Th2-type memory follows CD8+ lymphocyte-driven and eosinophil-mediated rejection of a spontaneous mouse mammary adenocarcinoma engineered to release IL-4.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(12):5659-73.
1994: Maria Ferrantini; Mirella Giovarelli; Andrea Modesti; Piero Musiani; Anna Modica; Massimo Venditti; E Peretti; Pier-Luigi Lollini; Patrizia Nanni; Guido Forni
IFN-alpha 1 gene expression into a metastatic murine adenocarcinoma (TS/A) results in CD8+ T cell-mediated tumor rejection and development of antitumor immunity. Comparative studies with IFN-gamma-producing TS/A cells.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(10):4604-15.
1994: Guido Forni; G Parmiani; Anna Guarini; R Foà
Gene transfer in tumor therapy.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5(9):789-94.
1994: Tiziana Musso; Maria Carla Bosco; Dan Longo; Igor Espinoza-Delgado; A Sica; G W Cox; G L Gusella; Guido Forni; Luigi Varesio
LPS-inducible nuclear factor in human monocytes that binds the negative regulatory element of the HIV LTR.
Journal of leukocyte biology 1994;56(1):21-6.
1994: Alessandro Cignetti; Anna Guarini; Antonino Carbone; M Forni; K Cronin; Guido Forni; B Gansbacher; Robin Foa
Transduction of the IL2 gene into human acute leukemia cells: induction of tumor rejection without modifying cell proliferation and IL2 receptor expression.
Journal of the National Cancer Institute 1994;86(10):785-91.
1994: Michela Paganuzzi; Paola Marroni; A Pezzolo; Giorgio Gimelli; Federica Cavallo; F Di Pierro; P De Angelis; Guido Forni; Carlo E Grossi
Genotypic, phenotypic and biological characterization of a novel human lung adenocarcinoma cell line (LC 89)
Oncology 1994;51(3):220-3.
1994: Giorgio Cortesina; Antonella De Stefani; E Galeazzi; G P Cavallo; F Badellino; G Margarino; C Jemma; Guido Forni
Temporary regression of recurrent squamous cell carcinoma of the head and neck is achieved with a low but not with a high dose of recombinant interleukin 2 injected perilymphatically.
British journal of cancer 1994;69(3):572-6.
1994: Francesco Novelli; F Di Pierro; P Francia di Celle; S Bertini; P Affaticati; G Garotta; Guido Forni
Environmental signals influencing expression of the IFN-gamma receptor on human T cells control whether IFN-gamma promotes proliferation or apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):496-504.
1994: Giorgio Cortesina; Antonella De Stefani; L Majore; Guido Forni; E Galeazzi
[Loco-regional treatment with low and high doses of interleukin-2 of head and neck squamous cell carcinoma recurrences].
Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale 1994;14(1):3-9.
1993: Guido Forni; Mirella Giovarelli; Federica Cavallo; M Consalvo; Attilio Allione; Andrea Modesti; Piero Musiani; Mario P Colombo
Cytokine-induced tumor immunogenicity: from exogenous cytokines to gene therapy.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(4):253-7.
1993: Federica Cavallo; F Di Pierro; Mirella Giovarelli; A Gulino; A Vacca; A Stoppacciaro; M Forni; Andrea Modesti; Guido Forni
Protective and curative potential of vaccination with interleukin-2-gene-transfected cells from a spontaneous mouse mammary adenocarcinoma.
Cancer research 1993;53(21):5067-70.
1993: Francesco Novelli; Mirella Giovarelli; R Gentz; Mario Zucca; F di Pierro; G Garotta; Guido Forni
Modulation of interferon-gamma receptor during human T lymphocyte alloactivation.
European journal of immunology 1993;23(6):1226-31.
1993: Andrea Modesti; Laura Masuelli; Anna Modica; G D'Orazi; Susanna Scarpa; M C Bosco; Guido Forni
Ultrastructural evidence of the mechanisms responsible for interleukin-4-activated rejection of a spontaneous murine adenocarcinoma.
International journal of cancer. Journal international du cancer 1993;53(6):988-93.
1993: Maria Carla Bosco; Tiziana Musso; G L Gusella; Mirella Giovarelli; M Forni; A Soleti; Laura Masuelli; Andrea Modesti; Guido Forni; Luigi Varesio
Selective transformation of host lymphocytes in vivo by retrovirus-producing macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(1):278-89.
1993: F Di Pierro; Federica Cavallo; F Pericle; S Bertini; Mirella Giovarelli; Guido Forni
Strategies for cytokine utilisation in tumor therapy.
Medical oncology and tumor pharmacotherapy 1993;10(1-2):53-9.
1992: Federica Cavallo; Mirella Giovarelli; A Gulino; A Vacca; A Stoppacciaro; Andrea Modesti; Guido Forni
Role of neutrophils and CD4+ T lymphocytes in the primary and memory response to nonimmunogenic murine mammary adenocarcinoma made immunogenic by IL-2 gene.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(11):3627-35.
1992: Federica Cavallo; M Forni; C Riccardi; A Soleti; F Di Pierro; Guido Forni
Growth and spread of human malignant T lymphoblasts in immunosuppressed nude mice: a model for meningeal leukemia.
Blood 1992;80(5):1279-83.
1992: Giorgio Cortesina; Antonella De Stefani; E Galeazzi; G P Cavallo; Mario Bussi; C Giordano; Guido Forni
Interleukin-2 and head and neck squamous cell carcinoma: clinical and pathological studies.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():50-1.
1992: Federica Cavallo; A Gulino; A Stoppacciaro; Mirella Giovarelli; Guido Forni
From exogenous cytokines to gene therapy: cytokine activated tumor inhibition.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():48-9.
1992: Guido Valente; L Ozmen; Francesco Novelli; Massimo Geuna; Giorgio Palestro; Guido Forni; G Garotta
Distribution of interferon-gamma receptor in human tissues.
European journal of immunology 1992;22(9):2403-12.
1992: C Jemma; Mirella Giovarelli; Sergio Vai; Federica Cavallo; Guido Forni
In vitro and in vivo immunomodulatory activity of ST 789 on two human lymphoblastic T cell lines.
Thymus 1992;19 Suppl 1():S79-87.
1991: Francesco Novelli; Mirella Giovarelli; R Reber-Liske; G Virgallita; G Garotta; Guido Forni
Blockade of physiologically secreted IFN-gamma inhibits human T lymphocyte and natural killer cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(4):1445-52.
1991: C Jemma; Alessandro Cignetti; Massimo Geuna; P Caretto; Sergio Vai; Guido Forni
In vitro and in vivo comparison of the activity of human lymphokine-activated killer (LAK) cells and adherent LAK cells.
Journal of immunotherapy : official journal of the Society for Biological Therapy 1991;10(3):189-99.
1991: Giorgio Cortesina; Antonella De Stefani; E Galeazzi; G P Cavallo; C Jemma; Mirella Giovarelli; Sergio Vai; Guido Forni
Interleukin-2 injected around tumor-draining lymph nodes in head and neck cancer.
Head & neck 1991;13(2):125-31.
1991: Giorgio Cortesina; Antonella De Stefani; E Galeazzi; Mario Bussi; C Giordano; G P Cavallo; C Jemma; Sergio Vai; Guido Forni; Guido Valente
The effect of preoperative local interleukin-2 (IL-2) injections in patients with head and neck squamous cell carcinoma. An immunological study.
Acta oto-laryngologica 1991;111(2):428-33.
1991: Federica Cavallo; C Riccardi; M Forni; F Pericle; Maria Carla Bosco; Mirella Giovarelli; A Soleti; Guido Forni
Growth and dissemination of human malignant lymphoblasts in immunosuppressed nu/nu mice.
Natural immunity and cell growth regulation 1991;10(5):256-64.
1990: Guido Valente; Antonella De Stefani; C Jemma; Mirella Giovarelli; Massimo Geuna; Giorgio Cortesina; Guido Forni; Giorgio Palestro
Infiltrating leukocyte populations and T-lymphocyte subsets in head and neck squamous cell carcinomas from patients receiving perilymphatic injections of recombinant interleukin 2. A pathologic and immunophenotypic study.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1990;3(6):702-8.
1990: Maria Carla Bosco; Mirella Giovarelli; M Forni; Andrea Modesti; Susanna Scarpa; Laura Masuelli; Guido Forni
Low doses of IL-4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently nonimmunogenic tumors and induce a tumor-specific immune memory.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(9):3136-43.
1990: Robin Foa; P Caretto; Maria Teresa Fierro; M Bonferroni; S Cardona; Anna Guarini; P Lista; Luigi Pegoraro; Franco Mandelli; Guido Forni
Interleukin 2 does not promote the in vitro and in vivo proliferation and growth of human acute leukaemia cells of myeloid and lymphoid origin.
British journal of haematology 1990;75(1):34-40.
1990: silvio Roncella; D Ramarli; M K Cooper; M Forni; P Caretto; M Rowe; P Francia di Celle; M Sessarego; R Foà; Guido Forni
Establishment of an EBV-positive lymphoblastoid cell line that grows as a lymphoma in nude mice and expresses membrane CD2 molecules.
International journal of cancer. Journal international du cancer 1990;45(2):299-307.
1990: silvio Roncella; P Caretto; Guido Forni; Giovanna Cutrona; A Verde; D Ramarli; P F de Celle; R Foá; M Sessarego; Vito Pistoia
Assessment of the potential malignancy of Epstein-Barr virus (EBV)-infected B cells in AIDS-related disorders.
Cancer detection and prevention 1990;14(3):325-9.
1990: Guido Forni; Mirella Giovarelli; C Jemma; M C Bosco; P Caretto; Andrea Modesti; A Santoni; M Forni; Giorgio Cortesina; Antonella De Stefani
Perilymphatic injections of cytokines: a new tool in active cancer immunotherapy. Experimental rationale and clinical findings.
Annali dell'Istituto superiore di sanità 1990;26(3-4):397-409.
1989: P Musiani; E De Campora; S Valitutti; F Castellino; C Calearo; G Cortesina; M Giovarelli; C Jemma; Antonella De Stefani; Guido Forni
Effect of low doses of interleukin-2 injected perilymphatically and peritumorally in patients with advanced primary head and neck squamous cell carcinoma.
Journal of biological response modifiers 1989;8(6):571-8.
1989: Giorgio Cortesina; Antonella De Stefani; M Giovarelli; M G Barioglio; G P Cavallo; E Galeazzi; C Jemma; Guido Forni
[Perilymphatic injection of interleukin-2 (IL-2) in recurrent squamous cell carcinoma of the head and neck].
Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale 1989;9(5):453-61.
1989: Guido Forni; Tiziana Musso; C Jemma; D Boraschi; A Tagliabue; Mirella Giovarelli
Lymphokine-activated tumor inhibition in mice. Ability of a nonapeptide of the human IL-1 beta to recruit anti-tumor reactivity in recipient mice.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(2):712-8.
1989: silvio Roncella; P Caretto; Guido Forni; Giovanna Cutrona; A Verde; D Ramarli; P F di Celle; R Foà; M Sessarego; Vito Pistoia
Studies on the oncogenic potential of Epstein-Barr-virus (EBV)-infected B cells in AIDS-related disorders.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():78-82.
1989: Guido Forni; Mirella Giovarelli; M C Bosco; P Caretto; Andrea Modesti; D Boraschi
Lymphokine-activated tumor inhibition: combinatory activity of a synthetic nonapeptide from interleukin-1, interleukin-2, interleukin-4, and interferon-gamma injected around tumor-draining lymph nodes.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():62-5.
1988: Giorgio Cortesina; Antonella De Stefani; Mirella Giovarelli; M G Barioglio; G P Cavallo; C Jemma; Guido Forni
Treatment of recurrent squamous cell carcinoma of the head and neck with low doses of interleukin-2 injected perilymphatically.
Cancer 1988;62(12):2482-5.
1988: Guido Forni; H Fujiwara; F Martino; T Hamaoka; C Jemma; P Caretto; Mirella Giovarelli
Helper strategy in tumor immunology: expansion of helper lymphocytes and utilization of helper lymphokines for experimental and clinical immunotherapy.
Cancer metastasis reviews 1988;7(4):289-309.
1988: Mirella Giovarelli; A Santoni; C Jemma; Tiziana Musso; A M Giuffrida; G Cavallo; Santo Landolfo; Guido Forni
Obligatory role of IFN-gamma in induction of lymphokine-activated and T lymphocyte killer activity, but not in boosting of natural cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(8):2831-6.
1988: M C Bosco; Mirella Giovarelli; Guido Forni
Ability of interleukin-4 to elicit an immunoreaction against a murine tumor.
Giornale di batteriologia, virologia ed immunologia 1988;81(1-12):3-9.
1988: Mirella Giovarelli; Robin Foa; G Benetton; P Lusso; Maria Teresa Fierro; Guido Forni
Release of interleukin-2-like material by B-chronic lymphocytic leukemia cells. An autocrine or paracrine model of production and utilization?
Leukemia research 1988;12(3):201-9.
1988: Maria Teresa Fierro; X S Liao; P Lusso; M Bonferroni; Lina Matera; A Cesano; P Lista; R Arione; Guido Forni; Robin Foa
In vitro and in vivo susceptibility of human leukemic cells to lymphokine activated killer activity.
Leukemia 1988;2(1):50-4.
1988: Robin Foa; Mirella Giovarelli; Maria Teresa Fierro; M Bonferroni; Guido Forni
Autocrine or paracrine models of cytokine production and utilization in B-cell chronic lymphocytic leukaemia.
Nouvelle revue française d'hématologie 1988;30(5-6):339-41.
1988: Guido Forni; G P Cavallo; Mirella Giovarelli; G Benetton; C Jemma; M G Barioglio; Antonella De Stefani; M Forni; A Santoni; Andrea Modesti
Tumor immunotherapy by local injection of interleukin 2 and non-reactive lymphocytes. Experimental and clinical results.
Progress in experimental tumor research 1988;32():187-212.
1987: Mirella Giovarelli; R Arione; C Jemma; Tiziana Musso; G Benetton; Guido Forni; P Cornaglia-Ferraris
In vitro and in vivo immunomodulatory activity of an N-9 arginyl hypoxanthine derivative (PCF-39).
International journal of immunopharmacology 1987;9(6):659-67.
1987: Guido Forni; Tiziana Musso; A Santoni; Mirella Giovarelli
Local administration of interleukin-2 activates lymphocytes from tumor bearing mice to recruit host immunoreactivity and inhibit tumor growth.
Progress in clinical and biological research 1987;244():105-14.
1987: Robin Foa; Maria Teresa Fierro; Mirella Giovarelli; P Lusso; G Benetton; M Bonferroni; Guido Forni
Immunoregulatory T-cell defects in B-cell chronic lymphocytic leukemia: cause or consequence of the disease? The contributory role of decreased availability of interleukin 2 (IL-2).
Blood cells 1987;12(2):399-412.
1986: M G Martinotti; R Arione; R Foà; L Pegoraro; C Jemma; Guido Forni
Serial transplantation of a human acute T lymphoblastic leukemia into nude mice.
Tumori 1986;72(6):553-8.