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Irmgard Förster

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Publications

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Kirsten Gerloff; Julia Kolling; Dora I A Pereira; Jonathan J Powell; Catrin Albrecht; Agnes W Boots; Nuno Faria; Irmgard Förster; Roel P F Schins
Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells.
Julia Tigges; Heike Weighardt; Sandra Wolff; Josef Abel; Irmgard Förster; Christine Götz; Thomas Haarmann-Stemmann; Ulrike Huebenthal; Zippora Kohne; Jean Krutmann; Hans F Merk; Ellen Fritsche
Aryl hydrocarbon receptor repressor (AhRR) function revisited: repression of CYP1 activity in human skin fibroblasts is not related to AhRR expression.
Theresa Köhler; Boris Reizis; Heike Weighardt; Randall S Johnson; Irmgard Förster
Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migration.

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All Publications

2013: Kirsten Gerloff; Julia Kolling; Dora I A Pereira; Jonathan J Powell; Catrin Albrecht; Agnes W Boots; Nuno Faria; Irmgard Förster; Roel P F Schins
Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells.
Nanotoxicology 2013;7():353-66.
2013: Julia Tigges; Heike Weighardt; Sandra Wolff; Josef Abel; Irmgard Förster; Christine Götz; Thomas Haarmann-Stemmann; Ulrike Huebenthal; Zippora Kohne; Jean Krutmann; Hans F Merk; Ellen Fritsche
Aryl hydrocarbon receptor repressor (AhRR) function revisited: repression of CYP1 activity in human skin fibroblasts is not related to AhRR expression.
The Journal of investigative dermatology 2013;133(1):87-96.
2012: Theresa Köhler; Boris Reizis; Heike Weighardt; Randall S Johnson; Irmgard Förster
Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migration.
European journal of immunology 2012;42(5):1226-36.
2012: Kirsten Gerloff; Julia Kolling; Catrin Albrecht; Agnes W Boots; Emanuele Carella; Ivana Fenoglio; Irmgard Förster; Roel P F Schins
Distinctive toxicity of TiO2 rutile/anatase mixed phase nanoparticles on Caco-2 cells.
Chemical research in toxicology 2012;25(3):646-55.
2012: Karola Poppensieker; Marco Prinz; Jennifer Raasch; Stefanie Scheu; Beatrix Schumak; Britta Schürmann; Ari Waisman; Andreas Zimmer; Philipp Dresing; Eva Drews; Irmgard Förster; Luisa Klotz; Percy A Knolle; Andreas Limmer; Wolfgang Maier; Alexander Mildner; David-Marian Otte; Judith Alferink
CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(10):3897-902.
2012: Alexander F Heiseke; Anne B Krug; Hans-Anton Lehr; Antonia C Faul; Irmgard Förster; Roland M Schmid; Wolfgang Reindl
CCL17 promotes intestinal inflammation in mice and counteracts regulatory T cell-mediated protection from colitis.
Gastroenterology 2012;142(2):335-45.
2011: Meike Winter; Hans-Dietmar Beer; Veit Hornung; Ursula Krämer; Roel P F Schins; Irmgard Förster
Activation of the inflammasome by amorphous silica and TiO2 nanoparticles in murine dendritic cells.
Nanotoxicology 2011;5(3):326-40.
2011: Kirsten Gerloff; Catrin Albrecht; Agnes W Boots; Irmgard Förster; Roel P F Schins
Particles which may occur in food or food packaging can exert cytotoxicity and (oxidative) DNA damage in target cells of the human intestine.
Nanotoxicology 2011;5(2):282-3.
2011: Sabine Specht; Jutta K Frank; Judith Alferink; Bettina Dubben; Laura E Layland; Gaelle Denece; Odile Bain; Irmgard Förster; Carsten J Kirschning; Coralie Martin; Achim Hoerauf
CCL17 controls mast cells for the defense against filarial larval entry.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(8):4845-52.
2011: Brian Wan-Chi Tse; Pamela Joan Russell; Irmgard Förster; Matthias Lochner; Carl Andrew Power
IL-18 inhibits growth of murine orthotopic prostate carcinomas via both adaptive and innate immune mechanisms.
PloS one 2011;6(9):e24241.
2010: Bodo Speckmann; Antonio Pinto; Meike Winter; Irmgard Förster; Helmut Sies; Holger Steinbrenner
Proinflammatory cytokines down-regulate intestinal selenoprotein P biosynthesis via NOS2 induction.
Free radical biology & medicine 2010;49(5):777-85.
2008: Matthias Lochner; Kathrin Kastenmüller; Michael Neuenhahn; Heike Weighardt; Dirk H Busch; Wolfgang Reindl; Irmgard Förster
Decreased susceptibility of mice to infection with Listeria monocytogenes in the absence of interleukin-18.
Infection and immunity 2008;76(9):3881-90.
2008: Susanne Stutte; Bettina Jux; Charlotte Esser; Irmgard Förster
CD24a expression levels discriminate Langerhans cells from dermal dendritic cells in murine skin and lymph nodes.
The Journal of investigative dermatology 2008;128(6):1470-5.
2008: Andrew L Croxford; Ozlem Akilli-Ozturk; Frédéric Rieux-Laucat; Irmgard Förster; Ari Waisman; Thorsten Buch
MHC-restricted T cell receptor signaling is required for alpha beta TCR replacement of the pre T cell receptor.
European journal of immunology 2008;38(2):391-9.
2007: Bernd Rebholz; Ingo Haase; Birgit Eckelt; Stephan Paxian; Michael J Flaig; Kamran Ghoreschi; Sergei A Nedospasov; Reinhard Mailhammer; Svenja Debey-Pascher; Joachim L Schultze; Günther Weindl; Irmgard Förster; Ralf Huss; Athanasios Stratis; Thomas Ruzicka; Martin Röcken; Klaus Pfeffer; Roland M Schmid; Rudolf A Rupec
Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin.
Immunity 2007;27(2):296-307.
2007: Jan P Tuckermann; Anna Kleiman; Richard Moriggl; Rainer Spanbroek; Anita Neumann; Anett Illing; Björn E Clausen; Brenda Stride; Irmgard Förster; Andreas J R Habenicht; Holger M Reichardt; François Tronche; Wolfgang Schmid; Günther Schütz
Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy.
The Journal of clinical investigation 2007;117(5):1381-90.
2007: Wolfgang Reindl; Susanne Weiss; Hans-Anton Lehr; Irmgard Förster
Essential crosstalk between myeloid and lymphoid cells for development of chronic colitis in myeloid-specific signal transducer and activator of transcription 3-deficient mice.
Immunology 2007;120(1):19-27.
2006: Thorsten Buch; Bojan Polic; Björn E Clausen; Susanne Weiss; Ozlem Akilli-Ozturk; Cheong-Hee Chang; Richard Flavell; Ansgar Schulz; Stipan Jonjic; Ari Waisman; Irmgard Förster
MHC class II expression through a hitherto unknown pathway supports T helper cell-dependent immune responses: implications for MHC class II deficiency.
Blood 2006;107(4):1434-44.
2005: Rudolf A Rupec; Franziska Jundt; Bernd Rebholz; Birgit Eckelt; Günther Weindl; Thomas Herzinger; Michael J Flaig; Sabine Moosmann; Gerd Plewig; Bernd Dörken; Irmgard Förster; Ralf Huss; Klaus Pfeffer
Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha.
Immunity 2005;22(4):479-91.
2005: Sergei Grivennikov; Alexei Tumanov; Dmitry J Liepinsh; Andrei A Kruglov; Boris I Marakusha; Alexander N Shakhov; Takaya Murakami; Ludmila N Drutskaya; Irmgard Förster; Björn E Clausen; Lino Tessarollo; Bernhard RYFFEL; Dmitry V Kuprash; Sergei A Nedospasov
Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects.
Immunity 2005;22(1):93-104.
2004: Anna Vossenkämper; Daniela Struck; Cosme Alvarado Esquivel; Tobias Went; Kioyshi Takeda; Shizuo Akira; Klaus Pfeffer; Gottfried Alber; Matthias Lochner; Irmgard Förster; Oliver Liesenfeld
Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control.
European journal of immunology 2004;34(11):3197-207.
2004: Irmgard Förster
Analysis of B-cell life-span and homeostasis.
Methods in molecular biology (Clifton, N.J.) 2004;271():59-66.
2003: Edwin Kanters; Manolis Pasparakis; Marion J J Gijbels; Monique N Vergouwe; Iris Partouns-Hendriks; Remond J A Fijneman; Björn E Clausen; Irmgard Förster; Mark M Kockx; Klaus Rajewsky; Georg Kraal; Marten H Hofker; Menno de Winther
Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.
The Journal of clinical investigation 2003;112(8):1176-85.
2003: Ben A Croker; Danielle L Krebs; Jian-Guo Zhang; Samuel Wormald; Tracy A Willson; Edouard G Stanley; Lorraine Robb; Christopher J Greenhalgh; Irmgard Förster; Björn E Clausen; Nicos A Nicola; Donald Metcalf; Douglas J Hilton; Andrew W Roberts; Warren S Alexander
SOCS3 negatively regulates IL-6 signaling in vivo.
Nature immunology 2003;4(6):540-5.
2003: Thorsten Cramer; Yuji Yamanishi; Björn E Clausen; Irmgard Förster; Rafal Pawlinski; Nigel Mackman; Volker H Haase; Rudolf Jaenisch; Maripat Corr; Victor Nizet; Gary S Firestein; Hans-Peter Gerber; Napoleone Ferrara; Randall S Johnson
HIF-1alpha is essential for myeloid cell-mediated inflammation.
Cell 2003;112(5):645-57.
2003: Judith Alferink; Ivo Lieberam; Wolfgang Reindl; Andrea Behrens; Susanne Weiss; Norbert Hüser; Klaus Gerauer; Ralf Ross; Angelika B Reske-Kunz; Parviz Ahmad-Nejad; Hermann Wagner; Irmgard Förster
Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen.
The Journal of experimental medicine 2003;197(5):585-99.
2002: Sonja Seewaldt; Judith Alferink; Irmgard Förster
Interleukin-10 is crucial for maintenance but not for developmental induction of peripheral T cell tolerance.
European journal of immunology 2002;32(12):3607-16.
2002: Thorsten Buch; Frédéric Rieux-Laucat; Irmgard Förster; Klaus Rajewsky
Failure of HY-specific thymocytes to escape negative selection by receptor editing.
Immunity 2002;16(5):707-18.
2002: Matthias Lochner; Irmgard Förster
Anti-interleukin-18 therapy in murine models of inflammatory bowel disease.
Pathobiology : journal of immunopathology, molecular and cellular biology 2002;70(3):164-9.
2002: Matthias Lochner; Hermann Wagner; Meinhard Classen; Irmgard Förster
Generation of neutralizing mouse anti-mouse IL-18 antibodies for inhibition of inflammatory responses in vivo.
Journal of immunological methods 2002;259(1-2):149-57.
1999: Ivo Lieberam; Irmgard Förster
The murine beta-chemokine TARC is expressed by subsets of dendritic cells and attracts primed CD4+ T cells.
European journal of immunology 1999;29(9):2684-94.
1999: Björn E Clausen; C Burkhardt; Walter Reith; R Renkawitz; Irmgard Förster
Conditional gene targeting in macrophages and granulocytes using LysMcre mice.
Transgenic research 1999;8(4):265-77.
1999: K Takeda; Björn E Clausen; T Kaisho; T Tsujimura; N Terada; Irmgard Förster; S Akira
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.
Immunity 1999;10(1):39-49.
1998: Björn E Clausen; jean-marc waldburger; Frieder Schwenk; Emmanuèle Barras; Bernard Mach; Klaus Rajewsky; Irmgard Förster; Walter Reith
Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice.
Immunity 1998;8(2):143-55.
1998: Irmgard Förster
Controlling autoreactivity of CD4 T cells by local tolerance induction.
Developmental immunology 1998;6(1-2):89-94.
1996: Irmgard Förster; I Lieberam
Peripheral tolerance of CD4 T cells following local activation in adolescent mice.
European journal of immunology 1996;26(12):3194-202.
1995: Irmgard Förster; R Hirose; J M Arbeit; Björn E Clausen; Douglas Hanahan
Limited capacity for tolerization of CD4+ T cells specific for a pancreatic beta cell neo-antigen.
Immunity 1995;2(6):573-85.
1992: H Gu; Irmgard Förster; Klaus Rajewsky
Study of murine B-cell development through analysis of immunoglobulin variable region genes.
Annals of the New York Academy of Sciences 1992;651():304-10.
1992: S Taki; M Schmitt; D Tarlinton; Irmgard Förster; Klaus Rajewsky
T cell-dependent antibody production by Ly-1 B cells.
Annals of the New York Academy of Sciences 1992;651():328-35.
1992: D Tarlinton; Irmgard Förster; Klaus Rajewsky
An explanation for the defect in secretion of IgM Mott cells and their predominant occurrence in the Ly-1 B cell compartment.
European journal of immunology 1992;22(2):531-9.
1991: Irmgard Förster; Werner Muller; B Schittek; Klaus Rajewsky
Generation of long-lived B cells in germ-free mice.
European journal of immunology 1991;21(7):1779-82.
1991: H Gu; D Tarlinton; Werner Muller; Klaus Rajewsky; Irmgard Förster
Most peripheral B cells in mice are ligand selected.
The Journal of experimental medicine 1991;173(6):1357-71.
1991: B Schittek; Klaus Rajewsky; Irmgard Förster
Dividing cells in bone marrow and spleen incorporate bromodeoxyuridine with high efficiency.
European journal of immunology 1991;21(1):235-8.
1991: Irmgard Förster; H Gu; Werner Muller; M Schmitt; D Tarlinton; Klaus Rajewsky
CD5 B cells in the mouse.
Current topics in microbiology and immunology 1991;173():247-51.
1990: H Gu; Irmgard Förster; Klaus Rajewsky
Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation.
The EMBO journal 1990;9(7):2133-40.
1990: Irmgard Förster; Klaus Rajewsky
The bulk of the peripheral B-cell pool in mice is stable and not rapidly renewed from the bone marrow.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(12):4781-4.
1989: Klaus Rajewsky; H Gu; P Vieira; Irmgard Förster
Growth and selection of B cells in vivo.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():209-17.
1989: Irmgard Förster; P Vieira; Klaus Rajewsky
Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse.
International immunology 1989;1(4):321-31.
1988: Irmgard Förster; H Gu; Klaus Rajewsky
Germline antibody V regions as determinants of clonal persistence and malignant growth in the B cell compartment.
The EMBO journal 1988;7(12):3693-703.
1987: Klaus Rajewsky; Irmgard Förster; A Cumano
Evolutionary and somatic selection of the antibody repertoire in the mouse.
Science (New York, N.Y.) 1987;238(4830):1088-94.