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Ron Fouchier

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Rogier Bodewes; Ron A M Fouchier; Marine L B Hillaire; Joost H C M Kreijtz; Thijs Kuiken; Nella J Nieuwkoop; Albert D M E Osterhaus; Geert van Amerongen; Peter van Run; Stella E Vogelzang-van Trierum; Guus F Rimmelzwaan
Infection of the upper respiratory tract with seasonal influenza A(H3N2) virus induces protective immunity in ferrets against infection with A(H1N1)pdm09 virus after intranasal, but not intratracheal, inoculation.
V Stalin Raj; Peter J M Rottier; Saskia L Smits; Volker Thiel; Ali Zaki; Berend Jan Bosch; Dick H W Dekkers; Jeroen A A Demmers; Ronald Dijkman; Christian Drosten; Ron A M Fouchier; Huihui Mou; Marcel Alexander Müller; Doreen Muth; Albert D M E Osterhaus; Bart L Haagmans
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC.
Marine L B Hillaire; Joost H C M Kreijtz; Albert D M E Osterhaus; Gerrie de Mutsert; Ron A M Fouchier; Stella E Vogelzang-van Trierum; Guus F Rimmelzwaan
Human T-cells directed to seasonal influenza A virus cross-react with 2009 pandemic influenza A (H1N1) and swine-origin triple-reassortant H3N2 influenza viruses.

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All Publications

2013: Rogier Bodewes; Ron A M Fouchier; Marine L B Hillaire; Joost H C M Kreijtz; Thijs Kuiken; Nella J Nieuwkoop; Albert D M E Osterhaus; Geert van Amerongen; Peter van Run; Stella E Vogelzang-van Trierum; Guus F Rimmelzwaan
Infection of the upper respiratory tract with seasonal influenza A(H3N2) virus induces protective immunity in ferrets against infection with A(H1N1)pdm09 virus after intranasal, but not intratracheal, inoculation.
Journal of virology 2013;87(8):4293-301.
2013: V Stalin Raj; Peter J M Rottier; Saskia L Smits; Volker Thiel; Ali Zaki; Berend Jan Bosch; Dick H W Dekkers; Jeroen A A Demmers; Ronald Dijkman; Christian Drosten; Ron A M Fouchier; Huihui Mou; Marcel Alexander Müller; Doreen Muth; Albert D M E Osterhaus; Bart L Haagmans
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC.
Nature 2013;495(7440):251-4.
2013: Marine L B Hillaire; Joost H C M Kreijtz; Albert D M E Osterhaus; Gerrie de Mutsert; Ron A M Fouchier; Stella E Vogelzang-van Trierum; Guus F Rimmelzwaan
Human T-cells directed to seasonal influenza A virus cross-react with 2009 pandemic influenza A (H1N1) and swine-origin triple-reassortant H3N2 influenza viruses.
The Journal of general virology 2013;94(Pt 3):583-92.
2013: Ron A M Fouchier; Adolfo García-Sastre; Yoshihiro Kawaoka
H5N1 virus: Transmission studies resume for avian flu.
Nature 2013;493(7434):609.
2013: Eefje J A Schrauwen; Theo M Bestebroer; Ron A M Fouchier; Albert D M E Osterhaus; Guus F Rimmelzwaan; Sander Herfst
Reassortment between Avian H5N1 and human influenza viruses is mainly restricted to the matrix and neuraminidase gene segments.
PloS one 2013;8(3):e59889.
2013: Nicola S Lewis; Pascal Lexmond; Ann Machablishvili; Tinatin Onashvili; Colin A Russell; Derek J Smith; Josanne H Verhagen; Oanh Vuong; Marina Donduashvili; Zurab Javakhishvili; Ron A M Fouchier
Avian influenza virus surveillance in wild birds in Georgia: 2009-2011.
PloS one 2013;8(3):e58534.
2013: Miranda de Graaf; Ron A M Fouchier; Sander Herfst; Theo M Luider; Albert D M E Osterhaus; Bob J Scholte; Eefje J A Schrauwen; Wilfred van Ijcken; Fatiha Zaaraoui-Boutahar; Jamil Aarbiou; Maarten Bijl; Peter C Burgers; Arno C Andeweg
Small hydrophobic protein of human metapneumovirus does not affect virus replication and host gene expression in vitro.
PloS one 2013;8(3):e58572.
2013: Marine L B Hillaire; Nella J Nieuwkoop; Albert D M E Osterhaus; Adrianus C M Boon; Gerrie de Mutsert; Ron A M Fouchier; Stella E Vogelzang-van Trierum; Guus F Rimmelzwaan
Binding of DC-SIGN to the hemagglutinin of influenza A viruses supports virus replication in DC-SIGN expressing cells.
PloS one 2013;8(2):e56164.
2013: Eveline Kindler; Marcel Alexander Müller; Doreen Muth; Regulo Rodriguez; Ronald Dijkman; Christian Drosten; Ron A M Fouchier; Robert Geffers; Ole J Hamming; Rune Hartmann; Hulda R Jónsdóttir; Volker Thiel
Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential.
mBio 2013;4(1):e00611-12.
2012: Rogier Bodewes; Ron A M Fouchier; Pieter L A Fraaij; Martina M Geelhoed-Mieras; Joost H C M Kreijtz; Albert D M E Osterhaus; Guus F Rimmelzwaan
Annual influenza vaccination affects the development of heterosubtypic immunity.
Vaccine 2012;30(51):7407-10.
2012: Ursula Höfle; Ron A M Fouchier; Lonneke M Leijten; Albert D M E Osterhaus; Geert Van Amerongen; M W G van de Bildt; Josanne H Verhagen; Thijs Kuiken
Tissue tropism and pathology of natural influenza virus infection in black-headed gulls (Chroicocephalus ridibundus).
Avian pathology : journal of the W.V.P.A 2012;41(6):547-53.
2012: Ali M Zaki; Theo M Bestebroer; Albert D M E Osterhaus; Sander van Boheemen; Ron A M Fouchier
Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia.
The New England journal of medicine 2012;367(19):1814-20.
2012: Marine L B Hillaire; Nella J Nieuwkoop; Albert D M E Osterhaus; Ron A M Fouchier; Henk P Haagsman; Martin van Eijk; Stella E Vogelzang-van Trierum; Guus F Rimmelzwaan
The number and position of N-linked glycosylation sites in the hemagglutinin determine differential recognition of seasonal and 2009 pandemic H1N1 influenza virus by porcine surfactant protein D.
Virus research 2012;169(1):301-5.
2012: Kim B Westgeest; Theo M Bestebroer; Miranda de Graaf; Jan C de Jong; Mathieu Fourment; Albert D M E Osterhaus; Guus F Rimmelzwaan; Colin A Russell; Derek J Smith; Gavin J D Smith; Monique I J Spronken; R H T Van Beek; Ron A M Fouchier
Genetic evolution of the neuraminidase of influenza A (H3N2) viruses from 1968 to 2009 and its correspondence to haemagglutinin evolution.
The Journal of general virology 2012;93(Pt 9):1996-2007.
2012: Colin A Russell; Eefje J A Schrauwen; David L Smith; Sander van Boheemen; André E X Brown; david burke; Judith M Fonville; Ron A M Fouchier; Sander Herfst; Sarah L James; Leah Katzelnick; Yoshihiro Kawaoka; Thijs Kuiken; Martin Linster; Eileen Maher; Ana Mosterín; Gabriele Neumann; Albert D M E Osterhaus; Derek J Smith
The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host.
Science (New York, N.Y.) 2012;336(6088):1541-7.
2012: Sander Herfst; Martin Linster; Vincent J Munster; Albert D M E Osterhaus; Guus F Rimmelzwaan; Eefje J A Schrauwen; Derek J Smith; Erin M Sorrell; Theo M Bestebroer; david burke; Salin Chutinimitkul; Emmie de Wit; Ron A M Fouchier
Airborne transmission of influenza A/H5N1 virus between ferrets.
Science (New York, N.Y.) 2012;336(6088):1534-41.
2012: Sander Herfst; Albert D M E Osterhaus; Ron A M Fouchier
The future of research and publication on altered H5N1 viruses.
The Journal of infectious diseases 2012;205(11):1628-31.
2012: Alexandra S Gambaryan; Hans-Dieter Klenk; Scott L Krauss; Jill Banks; Nicolai V Bovin; Ilaria Capua; Giovanni Cattoli; Ron A M Fouchier; Tatyana Matrosovich; Vincent J Munster; Jennifer Philipp; Robert G Webster; Mikhail Matrosovich
Receptor-binding profiles of H7 subtype influenza viruses in different host species.
Journal of virology 2012;86(8):4370-9.
2012: Eefje J A Schrauwen; Peter van Run; Theo M Bestebroer; Rogier Bodewes; Ron A M Fouchier; Sander Herfst; Joost H C M Kreijtz; Thijs Kuiken; Lonneke M Leijten; Martin Linster; Albert D M E Osterhaus; Guus F Rimmelzwaan; Debby van Riel
The multibasic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets.
Journal of virology 2012;86(7):3975-84.
2012: Ron A M Fouchier; Sander Herfst; Albert D M E Osterhaus
Public health and biosecurity. Restricted data on influenza H5N1 virus transmission.
Science (New York, N.Y.) 2012;335(6069):662-3.
2012: Ron A M Fouchier; Adolfo García-Sastre; Yoshihiro Kawaoka
Pause on avian flu transmission studies.
Nature 2012;481(7382):443.
2012: Marcel Alexander Müller; Doreen Muth; Albert D M E Osterhaus; V Stalin Raj; Saskia L Smits; Sabine Specht; Tasnim Suliman; Marco Tschapka; Robert Wollny; Ali M Zaki; Katrin Zimmermann; Isabella Eckerle; Ron A M Fouchier; Bart L Haagmans; Stephan Kallies; Benjamin Meyer; Theo M Bestebroer; Tabea Binger; Christian Drosten
Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines.
mBio 2012;3(6):.
2012: Sander van Boheemen; Ali Moh Zaki; Theo M Bestebroer; Miranda de Graaf; Alexander E Gorbalenya; Bart L Haagmans; Chris Lauber; Albert D M E Osterhaus; V Stalin Raj; Eric J Snijder; Ron A M Fouchier
Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans.
mBio 2012;3(6):.
2012: Gabriele Neumann; Catherine A Macken; Ron A M Fouchier; Alexander I Karasin; Yoshihiro Kawaoka
Egyptian H5N1 influenza viruses-cause for concern?
PLoS pathogens 2012;8(11):e1002932.
2012: Ron A M Fouchier; Adolfo García-Sastre; Yoshihiro Kawaoka
The pause on Avian H5N1 influenza virus transmission research should be ended.
mBio 2012;3(5):.
2012: Josanne H Verhagen; Oanh Vuong; Pascal Lexmond; Frank Majoor; Vincent J Munster; Albert D M E Osterhaus; Guus F Rimmelzwaan; Martin Schutten; Roy Slaterus; Job B G Stumpel; Ron A M Fouchier
Avian influenza a virus in wild birds in highly urbanized areas.
PloS one 2012;7(6):e38256.
2012: Gunnar Gunnarsson; Keith A Hobson; Neus Latorre-Margalef; Björn Olsen; Steven L Van Wilgenburg; Johan Elmberg; Ron A M Fouchier; Jonas Waldenström
Disease dynamics and bird migration--linking mallards Anas platyrhynchos and subtype diversity of the influenza A virus in time and space.
PloS one 2012;7(4):e35679.
2012: Sander van Boheemen; Josanne H Verhagen; Theo M Bestebroer; Sander Herfst; Albert D M E Osterhaus; Suzan D Pas; Ron A M Fouchier
A family-wide RT-PCR assay for detection of paramyxoviruses and application to a large-scale surveillance study.
PloS one 2012;7(4):e34961.
2011: Vicente Mas; Ron A M Fouchier; Sander Herfst; Albert D M E Osterhaus; José A Melero
Residues of the human metapneumovirus fusion (F) protein critical for its strain-related fusion phenotype: implications for the virus replication cycle.
Journal of virology 2011;85(23):12650-61.
2011: Rogier Bodewes; Ron A M Fouchier; Pieter L A Fraaij; Martina M Geelhoed-Mieras; Albert D M E Osterhaus; Harm A W M Tiddens; Carel A van Baalen; Fiona R van der Klis; Annemarie M C van Rossum; Guus F Rimmelzwaan
Annual vaccination against influenza virus hampers development of virus-specific CD8⁺ T cell immunity in children.
Journal of virology 2011;85(22):11995-2000.
2011: Marcel Jonges; Guus Koch; Arnaud Bataille; Remko Enserink; Ron A M Fouchier; Adam Meijer; Arjan Stegeman; Marion Koopmans
Comparative analysis of avian influenza virus diversity in poultry and humans during a highly pathogenic avian influenza A (H7N7) virus outbreak.
Journal of virology 2011;85(20):10598-604.
2011: Marine L B Hillaire; Joost H C M Kreijtz; Thijs Kuiken; Nella J Nieuwkoop; Albert D M E Osterhaus; Rogier Bodewes; Ron A M Fouchier; Martina M Geelhoed-Mieras; Stella E van Trierum; Guus F Rimmelzwaan
Cross-protective immunity against influenza pH1N1 2009 viruses induced by seasonal influenza A (H3N2) virus is mediated by virus-specific T-cells.
The Journal of general virology 2011;92(Pt 10):2339-49.
2011: Erhard van der Vries; Edwin Veldhuis Kroeze; Charles A B Boucher; Ron A M Fouchier; Thijs Kuiken; Lonneke M Leijten; Martin Linster; Albert D M E Osterhaus; Eefje J A Schrauwen; Martin Schutten; Koert J Stittelaar; Geert van Amerongen; Anne Van der Linden; Sander Herfst
Multidrug resistant 2009 A/H1N1 influenza clinical isolate with a neuraminidase I223R mutation retains its virulence and transmissibility in ferrets.
PLoS pathogens 2011;7(9):e1002276.
2011: Rogier Bodewes; Ron A M Fouchier; Joost H C M Kreijtz; Albert D M E Osterhaus; Guus F Rimmelzwaan; Geert van Amerongen; Thijs Kuiken
Pathogenesis of Influenza A/H5N1 virus infection in ferrets differs between intranasal and intratracheal routes of inoculation.
The American journal of pathology 2011;179(1):30-6.
2011: Eefje J A Schrauwen; Theo M Bestebroer; Vincent J Munster; Elzo de Wit; Sander Herfst; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Insertion of a multibasic cleavage site in the haemagglutinin of human influenza H3N2 virus does not increase pathogenicity in ferrets.
The Journal of general virology 2011;92(Pt 6):1410-5.
2011: Guus F Rimmelzwaan; R Joyce Verburgh; Nella J Nieuwkoop; Theo M Bestebroer; Ron A M Fouchier; Albert D M E Osterhaus
Use of GFP-expressing influenza viruses for the detection of influenza virus A/H5N1 neutralizing antibodies.
Vaccine 2011;29(18):3424-30.
2011: Pierre-Yves Daoust; Frederick S B Kibenge; Ron A M Fouchier; Marco W G van de Bildt; Debby van Riel; Thijs Kuiken
Replication of low pathogenic avian influenza virus in naturally infected Mallard ducks (Anas platyrhynchos) causes no morphologic lesions.
Journal of wildlife diseases 2011;47(2):401-9.
2011: R Bodewes; J H C M Kreijtz; Martina M Geelhoed-Mieras; Geert van Amerongen; R J Verburgh; S E van Trierum; Thijs Kuiken; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
Vaccination against seasonal influenza A/H3N2 virus reduces the induction of heterosubtypic immunity against influenza A/H5N1 virus infection in ferrets.
Journal of virology 2011;85(6):2695-702.
2011: R Bodewes; Gerrie de Mutsert; F R M van der Klis; M Ventresca; S Wilks; Derek J Smith; Marion Koopmans; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
Prevalence of antibodies against seasonal influenza A and B viruses in children in Netherlands.
Clinical and vaccine immunology : CVI 2011;18(3):469-76.
2011: Judith van den Brand; Joost H C M Kreijtz; Rogier Bodewes; Koert J Stittelaar; Geert van Amerongen; Thijs Kuiken; James Simon; Ron A M Fouchier; Giuseppe Del Giudice; Rino Rappuoli; Guus F Rimmelzwaan; Albert D M E Osterhaus
Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets.
Journal of virology 2011;85(6):2851-8.
2011: Eefje J A Schrauwen; Sander Herfst; Salin Chutinimitkul; Theo M Bestebroer; Guus F Rimmelzwaan; Albert D M E Osterhaus; Thijs Kuiken; Ron A M Fouchier
Possible increased pathogenicity of pandemic (H1N1) 2009 influenza virus upon reassortment.
Emerging infectious diseases 2011;17(2):200-8.
2011: Marine L B Hillaire; Thijs Kuiken; Albert D M E Osterhaus; Roland A Romijn; Xavier Saelens; Martin van Eijk; Debby van Riel; Stella E van Trierum; Ron A M Fouchier; Henk P Haagsman; Wieger Hemrika; Guus F Rimmelzwaan
Assessment of the antiviral properties of recombinant porcine SP-D against various influenza A viruses in vitro.
PloS one 2011;6(9):e25005.
2011: R Bodewes; Martina M Geelhoed-Mieras; Nella J Nieuwkoop; J A Hanson; C S David; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
Redundancy of the influenza A virus-specific cytotoxic T lymphocyte response in HLA-B*2705 transgenic mice limits the impact of a mutation in the immunodominant NP(383-391) epitope on influenza pathogenesis.
Virus research 2011;155(1):123-30.
2010: Bethany J Hoye; Vincent J Munster; Hiroshi Nishiura; Marcel Klaassen; Ron A M Fouchier
Surveillance of wild birds for avian influenza virus.
Emerging infectious diseases 2010;16(12):1827-34.
2010: Alexander P Gultyaev; Ron A M Fouchier; René C L Olsthoorn
Influenza virus RNA structure: unique and common features.
International reviews of immunology 2010;29(6):533-56.
2010: Salin Chutinimitkul; Sander Herfst; John Steel; Anice C Lowen; Jianqiang Ye; Debby van Riel; Eefje J A Schrauwen; Theo M Bestebroer; Björn Koel; david burke; Kyle H Sutherland-Cash; Chris S Whittleston; Colin A Russell; David J Wales; Derek J Smith; Marcel Jonges; Adam Meijer; Marion Koopmans; Guus F Rimmelzwaan; Thijs Kuiken; Albert D M E Osterhaus; Adolfo García-Sastre; Daniel R Perez; Ron A M Fouchier
Virulence-associated substitution D222G in the hemagglutinin of 2009 pandemic influenza A(H1N1) virus affects receptor binding.
Journal of virology 2010;84(22):11802-13.
2010: Joost H C M Kreijtz; Yasemin Süzer; Rogier Bodewes; Astrid Schwantes; Geert van Amerongen; R Joyce Verburgh; Gerrie de Mutsert; Judith van den Brand; Stella E van Trierum; Thijs Kuiken; Ron A M Fouchier; Albert D M E Osterhaus; Gerd Sutter; Guus F Rimmelzwaan
Evaluation of a modified vaccinia virus Ankara (MVA)-based candidate pandemic influenza A/H1N1 vaccine in the ferret model.
The Journal of general virology 2010;91(Pt 11):2745-52.
2010: Sander Herfst; Judith van den Brand; E J A Schrauwen; Elzo de Wit; Vincent J Munster; Geert van Amerongen; M Linster; F Zaaraoui; Wilfred F J van Ijcken; Guus F Rimmelzwaan; A D M E Osterhaus; Ron A M Fouchier; A C Andeweg; Thijs Kuiken
Pandemic 2009 H1N1 influenza virus causes diffuse alveolar damage in cynomolgus macaques.
Veterinary pathology 2010;47(6):1040-7.
2010: Jianqiang Ye; Hongxia Shao; Danielle Hickman; Matthew Angel; Kemin Xu; Yibin Cai; Haichen Song; Ron A M Fouchier; Ai-Jian Qin; Daniel R Perez
Intranasal delivery of an IgA monoclonal antibody effective against sublethal H5N1 influenza virus infection in mice.
Clinical and vaccine immunology : CVI 2010;17(9):1363-70.
2010: Juthatip Keawcharoen; Monique I J Spronken; O Vuong; Theo M Bestebroer; Vincent J Munster; A D M E Osterhaus; Guus F Rimmelzwaan; Ron A M Fouchier
Repository of Eurasian influenza A virus hemagglutinin and neuraminidase reverse genetics vectors and recombinant viruses.
Vaccine 2010;28(36):5803-9.
2010: Vincent J Munster; Eefje J A Schrauwen; Emmie de Wit; Judith van den Brand; Theo M Bestebroer; Sander Herfst; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Insertion of a multibasic cleavage motif into the hemagglutinin of a low-pathogenic avian influenza H6N1 virus induces a highly pathogenic phenotype.
Journal of virology 2010;84(16):7953-60.
2010: R Bodewes; J H C M Kreijtz; Geert van Amerongen; Martina M Geelhoed-Mieras; R J Verburgh; J G M Heldens; J Bedwell; Judith van den Brand; Thijs Kuiken; Carel A van Baalen; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
A single immunization with CoVaccine HT-adjuvanted H5N1 influenza virus vaccine induces protective cellular and humoral immune responses in ferrets.
Journal of virology 2010;84(16):7943-52.
2010: Salin Chutinimitkul; Debby van Riel; Vincent J Munster; Judith van den Brand; Guus F Rimmelzwaan; Thijs Kuiken; Albert D M E Osterhaus; Ron A M Fouchier; Emmie de Wit
In vitro assessment of attachment pattern and replication efficiency of H5N1 influenza A viruses with altered receptor specificity.
Journal of virology 2010;84(13):6825-33.
2010: Rogier Bodewes; Joost H C M Kreijtz; Marine L B Hillaire; Martina M Geelhoed-Mieras; Ron A M Fouchier; Albert D M E Osterhaus; Guus F Rimmelzwaan
Vaccination with whole inactivated virus vaccine affects the induction of heterosubtypic immunity against influenza virus A/H5N1 and immunodominance of virus-specific CD8+ T-cell responses in mice.
The Journal of general virology 2010;91(Pt 7):1743-53.
2010: Judith van den Brand; Koert J Stittelaar; Geert van Amerongen; Guus F Rimmelzwaan; James Simon; Emmie de Wit; Vincent J Munster; Theo Bestebroer; Ron A M Fouchier; Thijs Kuiken; Albert D M E Osterhaus
Severity of pneumonia due to new H1N1 influenza virus in ferrets is intermediate between that due to seasonal H1N1 virus and highly pathogenic avian influenza H5N1 virus.
The Journal of infectious diseases 2010;201(7):993-9.
2010: Debby van Riel; Michael A Den Bakker; Lonneke M E Leijten; Salin Chutinimitkul; Vincent J Munster; Emmie de Wit; Guus F Rimmelzwaan; Ron A M Fouchier; Albert D M E Osterhaus; Thijs Kuiken
Seasonal and pandemic human influenza viruses attach better to human upper respiratory tract epithelium than avian influenza viruses.
The American journal of pathology 2010;176(4):1614-8.
2010: Sander Herfst; Salin Chutinimitkul; Jianqiang Ye; Emmie de Wit; Vincent J Munster; Eefje J A Schrauwen; Theo M Bestebroer; Marcel Jonges; Adam Meijer; Marion Koopmans; Guus F Rimmelzwaan; Albert D M E Osterhaus; Daniel R Perez; Ron A M Fouchier
Introduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission.
Journal of virology 2010;84(8):3752-8.
2010: Ron A M Fouchier; Derek J Smith
Use of antigenic cartography in vaccine seed strain selection.
Avian diseases 2010;54(1 Suppl):220-3.
2010: Emmie de Wit; Vincent J Munster; Debby van Riel; Walter Emil Philipp Beyer; Guus F Rimmelzwaan; Thijs Kuiken; Albert D M E Osterhaus; Ron A M Fouchier
Molecular determinants of adaptation of highly pathogenic avian influenza H7N7 viruses to efficient replication in the human host.
Journal of virology 2010;84(3):1597-606.
2010: E van der Vries; M Jonges; Sander Herfst; JJ Maaskant; A Van der Linden; J Guldemeester; G I Aron; Theo M Bestebroer; Marion Koopmans; Adam Meijer; Ron A M Fouchier; A D M E Osterhaus; C A Boucher; Martin Schutten
Evaluation of a rapid molecular algorithm for detection of pandemic influenza A (H1N1) 2009 virus and screening for a key oseltamivir resistance (H275Y) substitution in neuraminidase.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2010;47(1):34-7.
2009: R Bodewes; Martina M Geelhoed-Mieras; J G M Heldens; J Glover; Bart N Lambrecht; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
The novel adjuvant CoVaccineHT increases the immunogenicity of cell-culture derived influenza A/H5N1 vaccine and induces the maturation of murine and human dendritic cells in vitro.
Vaccine 2009;27(49):6833-9.
2009: Guus F Rimmelzwaan; Joost H C M Kreijtz; Rogier Bodewes; Ron A M Fouchier; Albert D M E Osterhaus
Influenza virus CTL epitopes, remarkably conserved and remarkably variable.
Vaccine 2009;27(45):6363-5.
2009: Vincent J Munster; Ron A M Fouchier
Avian influenza virus: of virus and bird ecology.
Vaccine 2009;27(45):6340-4.
2009: J H C M Kreijtz; Yasemin Suezer; Gerrie de Mutsert; Judith van den Brand; Geert van Amerongen; Barbara S Schnierle; Thijs Kuiken; Ron A M Fouchier; Johannes Löwer; A D M E Osterhaus; Gerd Sutter; Guus F Rimmelzwaan
Preclinical evaluation of a modified vaccinia virus Ankara (MVA)-based vaccine against influenza A/H5N1 viruses.
Vaccine 2009;27(45):6296-9.
2009: Debby van Riel; Judith van den Brand; Vincent J Munster; T M Besteboer; Ron A M Fouchier; A D M E Osterhaus; Thijs Kuiken
Pathology and virus distribution in chickens naturally infected with highly pathogenic avian influenza A virus (H7N7) During the 2003 outbreak in The Netherlands.
Veterinary pathology 2009;46(5):971-6.
2009: J H C M Kreijtz; R Bodewes; Judith van den Brand; Gerrie de Mutsert; C Baas; Geert van Amerongen; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
Infection of mice with a human influenza A/H3N2 virus induces protective immunity against lethal infection with influenza A/H5N1 virus.
Vaccine 2009;27(36):4983-9.
2009: Vincent J Munster; Emmie de Wit; Judith van den Brand; Sander Herfst; Eefje J A Schrauwen; Theo M Bestebroer; David van de Vijver; Charles A Boucher; Marion Koopmans; Guus F Rimmelzwaan; Thijs Kuiken; Albert D M E Osterhaus; Ron A M Fouchier
Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets.
Science (New York, N.Y.) 2009;325(5939):481-3.
2009: Miranda de Graaf; Eefje J A Schrauwen; Sander Herfst; Geert van Amerongen; Albert D M E Osterhaus; Ron A M Fouchier
Fusion protein is the main determinant of metapneumovirus host tropism.
The Journal of general virology 2009;90(Pt 6):1408-16.
2009: Ron A M Fouchier; Vincent J Munster
Epidemiology of low pathogenic avian influenza viruses in wild birds.
Revue scientifique et technique (International Office of Epizootics) 2009;28(1):49-58.
2009: Neus Latorre-Margalef; Gunnar Gunnarsson; Vincent J Munster; Ron A M Fouchier; Albert D M E Osterhaus; Johan Elmberg; Björn Olsen; Anders Wallensten; Paul D Haemig; Thord Fransson; Lars Brudin; Jonas Waldenström
Effects of influenza A virus infection on migrating mallard ducks.
Proceedings. Biological sciences / The Royal Society 2009;276(1659):1029-36.
2009: Vincent J Munster; Chantal Baas; Pascal Lexmond; Theo M Bestebroer; Judith Guldemeester; Walter Emil Philipp Beyer; Emmie de Wit; Martin Schutten; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Practical considerations for high-throughput influenza A virus surveillance studies of wild birds by use of molecular diagnostic tests.
Journal of clinical microbiology 2009;47(3):666-73.
2009: J H C M Kreijtz; Yasemin Suezer; G de Mutsert; Judith van den Brand; G van Amerongen; Barbara S Schnierle; Thijs Kuiken; Ron A M Fouchier; Johannes Löwer; A D M E Osterhaus; Gerd Sutter; Guus F Rimmelzwaan
Recombinant modified vaccinia virus Ankara expressing the hemagglutinin gene confers protection against homologous and heterologous H5N1 influenza virus infections in macaques.
The Journal of infectious diseases 2009;199(3):405-13.
2009: Joost H C M Kreijtz; Yasemin Suezer; Gerrie de Mutsert; Geert van Amerongen; Astrid Schwantes; Judith van den Brand; Ron A M Fouchier; Johannes Löwer; Albert D M E Osterhaus; Gerd Sutter; Guus F Rimmelzwaan
MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization.
PloS one 2009;4(11):e7790.
2009: Rogier Bodewes; Joost H C M Kreijtz; Chantal Baas; Martina M Geelhoed-Mieras; Gerrie de Mutsert; Geert van Amerongen; Judith van den Brand; Ron A M Fouchier; Albert D M E Osterhaus; Guus F Rimmelzwaan
Vaccination against human influenza A/H3N2 virus prevents the induction of heterosubtypic immunity against lethal infection with avian influenza A/H5N1 virus.
PloS one 2009;4(5):e5538.
2008: Miranda de Graaf; Albert D M E Osterhaus; Ron A M Fouchier; Edward C Holmes
Evolutionary dynamics of human and avian metapneumoviruses.
The Journal of general virology 2008;89(Pt 12):2933-42.
2008: G F Rimmelzwaan; Jan C de Jong; G A Donker; Adam Meijer; Ron A M Fouchier; A D M E Osterhaus
[Influenza season 2007/'08 in the Netherlands: antigenic variation, oseltamivir resistance and vaccine composition for the 2008/'09 season].
Nederlands tijdschrift voor geneeskunde 2008;152(39):2138-44.
2008: Emmie de Wit; Yoshihiro Kawaoka; Menno D De Jong; Ron A M Fouchier
Pathogenicity of highly pathogenic avian influenza virus in mammals.
Vaccine 2008;26 Suppl 4():D54-8.
2008: Colin A Russell; Terry C Jones; Ian G Barr; Nancy J Cox; Rebecca J Garten; Vicky Gregory; Ian D Gust; Alan Hampson; Alan J Hay; Aeron C Hurt; Jan C de Jong; Anne Kelso; Alexander I Klimov; Tsutomu Kageyama; Naomi Komadina; Alan S Lapedes; Yi P Lin; Ana Mosterin; Masatsugu Obuchi; Takato Odagiri; Albert D M E Osterhaus; Guus F Rimmelzwaan; Michael W Shaw; Eugene Skepner; Klaus Stohr; Masato Tashiro; Ron A M Fouchier; Derek J Smith
Influenza vaccine strain selection and recent studies on the global migration of seasonal influenza viruses.
Vaccine 2008;26 Suppl 4():D31-4.
2008: Sander Herfst; Vicente Mas; Lorena S Ver; Rutger J Wierda; Albert D M E Osterhaus; Ron A M Fouchier; José A Melero
Low-pH-induced membrane fusion mediated by human metapneumovirus F protein is a rare, strain-dependent phenomenon.
Journal of virology 2008;82(17):8891-5.
2008: Sander Herfst; Eefje J A Schrauwen; Miranda de Graaf; Geert van Amerongen; Bernadette van den Hoogen; Rik de Swart; Albert D M E Osterhaus; Ron A M Fouchier
Immunogenicity and efficacy of two candidate human metapneumovirus vaccines in cynomolgus macaques.
Vaccine 2008;26(33):4224-30.
2008: Sander Herfst; Miranda de Graaf; Eefje J A Schrauwen; Leo Sprong; Karim Hussain; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
Generation of temperature-sensitive human metapneumovirus strains that provide protective immunity in hamsters.
The Journal of general virology 2008;89(Pt 7):1553-62.
2008: J H C M Kreijtz; Gerrie de Mutsert; Carel A van Baalen; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
Cross-recognition of avian H5N1 influenza virus by human cytotoxic T-lymphocyte populations directed to human influenza A virus.
Journal of virology 2008;82(11):5161-6.
2008: Colin A Russell; Terry C Jones; Ian G Barr; Nancy J Cox; Rebecca J Garten; Vicky Gregory; Ian D Gust; Alan Hampson; Alan J Hay; Aeron C Hurt; Jan C de Jong; Anne Kelso; Alexander I Klimov; Tsutomu Kageyama; Naomi Komadina; Alan S Lapedes; Yi P Lin; Ana Mosterin; Masatsugu Obuchi; Takato Odagiri; Albert D M E Osterhaus; Guus F Rimmelzwaan; Michael W Shaw; Eugene Skepner; Klaus Stohr; Masato Tashiro; Ron A M Fouchier; Derek J Smith
The global circulation of seasonal influenza A (H3N2) viruses.
Science (New York, N.Y.) 2008;320(5874):340-6.
2008: Juthatip Keawcharoen; Debby van Riel; Geert van Amerongen; Theo M Bestebroer; Walter Emil Philipp Beyer; Rob van Lavieren; Albert D M E Osterhaus; Ron A M Fouchier; Thijs Kuiken
Wild ducks as long-distance vectors of highly pathogenic avian influenza virus (H5N1).
Emerging infectious diseases 2008;14(4):600-7.
2008: Miranda de Graaf; Sander Herfst; Eefje J A Schrauwen; Ying Choi; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
Specificity and functional interaction of the polymerase complex proteins of human and avian metapneumoviruses.
The Journal of general virology 2008;89(Pt 4):975-83.
2008: Gunilla B Karlsson Hedestam; Ron A M Fouchier; Sanjay Phogat; Dennis R Burton; Joseph Sodroski; Richard Wyatt
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.
Nature reviews. Microbiology 2008;6(2):143-55.
2008: Emmie de Wit; Ron A M Fouchier
Emerging influenza.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2008;41(1):1-6.
2008: Sander Herfst; Ron A M Fouchier
Vaccination approaches to combat human metapneumovirus lower respiratory tract infections.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2008;41(1):49-52.
2007: Guus F Rimmelzwaan; Nella J Nieuwkoop; Gerrie de Mutsert; A C M Boon; Thijs Kuiken; Ron A M Fouchier; Albert D M E Osterhaus
Attachment of infectious influenza A viruses of various subtypes to live mammalian and avian cells as measured by flow cytometry.
Virus research 2007;129(2):175-81.
2007: Sander Herfst; Miranda de Graaf; Eefje J A Schrauwen; Nancy D Ulbrandt; Arnita Barber Barnes; Kannaki Senthil; Albert D M E Osterhaus; Ron A M Fouchier; Bernadette van den Hoogen
Immunization of Syrian golden hamsters with F subunit vaccine of human metapneumovirus induces protection against challenge with homologous or heterologous strains.
The Journal of general virology 2007;88(Pt 10):2702-9.
2007: Debby van Riel; Vincent J Munster; Emmie de Wit; Guus F Rimmelzwaan; Ron A M Fouchier; Albert D M E Osterhaus; Thijs Kuiken
Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals.
The American journal of pathology 2007;171(4):1215-23.
2007: Jan C de Jong; G F Rimmelzwaan; G A Donker; Adam Meijer; Ron A M Fouchier; A D M E Osterhaus
[The 2006/'07 influenza season in the Netherlands and the vaccine composition for the 2007/'08 season].
Nederlands tijdschrift voor geneeskunde 2007;151(39):2158-65.
2007: Mariette F Ducatez; Christophe Olinger; AA Owoade; Zekiba Tarnagda; M C Tahita; A Sow; Sébastien de Landtsheer; Wim Ammerlaan; J B Ouedraogo; A D M E Osterhaus; Ron A M Fouchier; Claude P Muller
Molecular and antigenic evolution and geographical spread of H5N1 highly pathogenic avian influenza viruses in western Africa.
The Journal of general virology 2007;88(Pt 8):2297-306.
2007: Miranda de Graaf; Sander Herfst; Eefje J A Schrauwen; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
An improved plaque reduction virus neutralization assay for human metapneumovirus.
Journal of virological methods 2007;143(2):169-74.
2007: Vincent J Munster; Emmie de Wit; Debby van Riel; Walter Emil Philipp Beyer; Guus F Rimmelzwaan; Albert D M E Osterhaus; Thijs Kuiken; Ron A M Fouchier
The molecular basis of the pathogenicity of the Dutch highly pathogenic human influenza A H7N7 viruses.
The Journal of infectious diseases 2007;196(2):258-65.
2007: Joost H C M Kreijtz; Yasemin Suezer; Geert van Amerongen; Gerrie de Mutsert; Barbara S Schnierle; John M Wood; Thijs Kuiken; Ron A M Fouchier; Johannes Lower; Albert D M E Osterhaus; Gerd Sutter; Guus F Rimmelzwaan
Recombinant modified vaccinia virus Ankara-based vaccine induces protective immunity in mice against infection with influenza virus H5N1.
The Journal of infectious diseases 2007;195(11):1598-606.
2007: E G M Berkhoff; Martina M Geelhoed-Mieras; Marcel Jonges; Derek J Smith; Ron A M Fouchier; Albert D M E Osterhaus; Guus F Rimmelzwaan
An amino acid substitution in the influenza A virus hemagglutinin associated with escape from recognition by human virus-specific CD4+ T-cells.
Virus research 2007;126(1-2):282-7.
2007: Vincent J Munster; Chantal Baas; Pascal Lexmond; Jonas Waldenström; Anders Wallensten; Thord Fransson; Guus F Rimmelzwaan; Walter Emil Philipp Beyer; Martin Schutten; Björn Olsen; Albert D M E Osterhaus; Ron A M Fouchier
Spatial, temporal, and species variation in prevalence of influenza A viruses in wild migratory birds.
PLoS pathogens 2007;3(5):e61.
2007: Joost D W Philippa; Chantal Baas; Walter Emil Philipp Beyer; Theo M Bestebroer; Ron A M Fouchier; Derek Smith; Willem Schaftenaar; Ab Osterhaus
Vaccination against highly pathogenic avian influenza H5N1 virus in zoos using an adjuvanted inactivated H5N2 vaccine.
Vaccine 2007;25(19):3800-8.
2007: E G M Berkhoff; Martina M Geelhoed-Mieras; Esther J Verschuren; Carel A van Baalen; Rob A Gruters; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
The loss of immunodominant epitopes affects interferon-gamma production and lytic activity of the human influenza virus-specific cytotoxic T lymphocyte response in vitro.
Clinical and experimental immunology 2007;148(2):296-306.
2007: Mariette F Ducatez; Zekiba Tarnagda; Marc C Tahita; Adama Sow; Sébastien de Landtsheer; Brandon Z Londt; Ian H Brown; D M E Osterhaus; Ron A M Fouchier; Jean Bosco Ouedraogo; Claude P Muller
Genetic characterization of HPAI (H5N1) viruses from poultry and wild vultures, Burkina Faso.
Emerging infectious diseases 2007;13(4):611-3.
2007: Emmie de Wit; Monique I J Spronken; Gaby Vervaet; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
A reverse-genetics system for Influenza A virus using T7 RNA polymerase.
The Journal of general virology 2007;88(Pt 4):1281-7.
2007: Bernadette van den Hoogen; Sander Herfst; Miranda de Graaf; Leo Sprong; Rob F van Lavieren; Geert van Amerongen; Selma Yüksel; Ron A M Fouchier; Albert D M E Osterhaus; Rik de Swart
Experimental infection of macaques with human metapneumovirus induces transient protective immunity.
The Journal of general virology 2007;88(Pt 4):1251-9.
2007: Jan C de Jong; Derek J Smith; Alan S Lapedes; Isabella Donatelli; Laura Campitelli; Giuseppe Barigazzi; K Van Reeth; T C Jones; Guus F Rimmelzwaan; A D M E Osterhaus; Ron A M Fouchier
Antigenic and genetic evolution of swine influenza A (H3N2) viruses in Europe.
Journal of virology 2007;81(8):4315-22.
2007: Anders Wallensten; Vincent J Munster; Neus Latorre-Margalef; Maria Brytting; Johan Elmberg; Ron A M Fouchier; Thord Fransson; Paul D Haemig; Malin Karlsson; Ake Lundkvist; Albert D M E Osterhaus; Martin Stervander; Jonas Waldenström; Olsen Björn
Surveillance of influenza A virus in migratory waterfowl in northern Europe.
Emerging infectious diseases 2007;13(3):404-11.
2007: E G M Berkhoff; Martina M Geelhoed-Mieras; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
Assessment of the extent of variation in influenza A virus cytotoxic T-lymphocyte epitopes by using virus-specific CD8+ T-cell clones.
The Journal of general virology 2007;88(Pt 2):530-5.
2007: J H C M Kreijtz; R Bodewes; Geert van Amerongen; Thijs Kuiken; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
Primary influenza A virus infection induces cross-protective immunity against a lethal infection with a heterosubtypic virus strain in mice.
Vaccine 2007;25(4):612-20.
2007: Jan A van Gils; Vincent J Munster; Reinder Radersma; Daan Liefhebber; Ron A M Fouchier; Marcel Klaassen
Hampered foraging and migratory performance in swans infected with low-pathogenic avian influenza A virus.
PloS one 2007;2(1):e184.
2007: Emmie de Wit; Theo M Bestebroer; Monique I J Spronken; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Rapid sequencing of the non-coding regions of influenza A virus.
Journal of virological methods 2007;139(1):85-9.
2006: E G M Berkhoff; Emmie de Wit; Martina M Geelhoed-Mieras; A C M Boon; Jori Symons; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
Fitness costs limit escape from cytotoxic T lymphocytes by influenza A viruses.
Vaccine 2006;24(44-46):6594-6.
2006: Emmie de Wit; Monique I J Spronken; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Evidence for specific packaging of the influenza A virus genome from conditionally defective virus particles lacking a polymerase gene.
Vaccine 2006;24(44-46):6647-50.
2006: Anders Wallensten; Vincent J Munster; Malin Karlsson; Ake Lundkvist; Maria Brytting; Martin Stervander; Albert D M E Osterhaus; Ron A M Fouchier; Björn Olsen
High prevalence of influenza A virus in ducks caught during spring migration through Sweden.
Vaccine 2006;24(44-46):6734-5.
2006: Vincent J Munster; Jan Veen; Björn Olsen; Rob Vogel; Albert D M E Osterhaus; Ron A M Fouchier
Towards improved influenza A virus surveillance in migrating birds.
Vaccine 2006;24(44-46):6729-33.
2006: Guus F Rimmelzwaan; Jan C de Jong; G A Donker; Adam Meijer; Ron A M Fouchier; A D M E Osterhaus
[The 2005-2006 influenza season in the Netherlands and the vaccine composition for the 2006-2007 season].
Nederlands tijdschrift voor geneeskunde 2006;150(40):2209-14.
2006: Nancy D Ulbrandt; Hong Ji; Nita K Patel; Jeffrey M Riggs; Yambasu Albert Brewah; Shannon Ready; Nanci E Donacki; Karyn M Folliot; Arnita Barber Barnes; Kannaki Senthil; Susan D Wilson; Mingzhong Chen; Lori Clarke; Mia M MacPhail; Jia Li; Robert M Woods; Kathleen L Coelingh; Jennifer L Reed; Michael P McCarthy; David Pfarr; Albert D M E Osterhaus; Ron A M Fouchier; Peter Kiener; JoAnn A Suzich
Isolation and characterization of monoclonal antibodies which neutralize human metapneumovirus in vitro and in vivo.
Journal of virology 2006;80(16):7799-806.
2006: Mariette F Ducatez; Christophe Olinger; AA Owoade; Sébastien de Landtsheer; Wim Ammerlaan; Hubert G M Niesters; A D M E Osterhaus; Ron A M Fouchier; Claude P Muller
Avian flu: multiple introductions of H5N1 in Nigeria.
Nature 2006;442(7098):37.
2006: A C M Boon; Gerrie de Mutsert; Ron A M Fouchier; Albert D M E Osterhaus; Guus F Rimmelzwaan
The hypervariable immunodominant NP418-426 epitope from the influenza A virus nucleoprotein is recognized by cytotoxic T lymphocytes with high functional avidity.
Journal of virology 2006;80(12):6024-32.
2006: Björn Olsen; Vincent J Munster; Anders Wallensten; Jonas Waldenström; Albert D M E Osterhaus; Ron A M Fouchier
Global patterns of influenza a virus in wild birds.
Science (New York, N.Y.) 2006;312(5772):384-8.
2006: Debby van Riel; Vincent J Munster; Emmie de Wit; Guus F Rimmelzwaan; Ron A M Fouchier; Ab D M E Osterhaus; Thijs Kuiken
H5N1 Virus Attachment to Lower Respiratory Tract.
Science (New York, N.Y.) 2006;312(5772):399.
2006: Thijs Kuiken; Ron A M Fouchier; Guus F Rimmelzwaan; Albert Osterhaus; Peter Roeder
Feline friend or potential foe?
Nature 2006;440(7085):741-2.
2006: Guus F Rimmelzwaan; Debby van Riel; Marianne Baars; Theo M Bestebroer; Geert van Amerongen; Ron A M Fouchier; Albert D M E Osterhaus; Thijs Kuiken
Influenza A virus (H5N1) infection in cats causes systemic disease with potential novel routes of virus spread within and between hosts.
The American journal of pathology 2006;168(1):176-83; quiz 364.
2005: Joost D W Philippa; Vincent J Munster; Hester van Bolhuis; Theo M Bestebroer; Willem Schaftenaar; Walter Emil Philipp Beyer; Ron A M Fouchier; Thijs Kuiken; Albert D M E Osterhaus
Highly pathogenic avian influenza (H7N7): vaccination of zoo birds and transmission to non-poultry species.
Vaccine 2005;23(50):5743-50.
2005: Jan C de Jong; Guus F Rimmelzwaan; Aad I M Bartelds; Adam Meijer; Ron A M Fouchier; A D M E Osterhaus
[The influenza season 2004/'05 in the Netherlands with the largest epidemic of the last 5 years caused by the virus variant A/California and the composition of the vaccine for the season 2005/'06].
Nederlands tijdschrift voor geneeskunde 2005;149(42):2355-61.
2005: Vincent J Munster; Anders Wallensten; Chantal Baas; Guus F Rimmelzwaan; Martin Schutten; Björn Olsen; Albert D M E Osterhaus; Ron A M Fouchier
Mallards and highly pathogenic avian influenza ancestral viruses, northern Europe.
Emerging infectious diseases 2005;11(10):1545-51.
2005: A C M Boon; Gerrie de Mutsert; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
Functional profile of human influenza virus-specific cytotoxic T lymphocyte activity is influenced by interleukin-2 concentration and epitope specificity.
Clinical and experimental immunology 2005;142(1):45-52.
2005: Emmie de Wit; Vincent J Munster; Monique I J Spronken; Theo M Bestebroer; Chantal Baas; Walter Emil Philipp Beyer; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Protection of mice against lethal infection with highly pathogenic H7N7 influenza A virus by using a recombinant low-pathogenicity vaccine strain.
Journal of virology 2005;79(19):12401-7.
2005: Thijs Kuiken; F A Leighton; Ron A M Fouchier; James LeDuc; J S M Peiris; A Schudel; Klaus Stöhr; A D M E Osterhaus
Public health. Pathogen surveillance in animals.
Science (New York, N.Y.) 2005;309(5741):1680-1.
2005: E G M Berkhoff; Emmie de Wit; Martina M Geelhoed-Mieras; A C M Boon; Jori Symons; Ron A M Fouchier; A D M E Osterhaus; Guus F Rimmelzwaan
Functional constraints of influenza A virus epitopes limit escape from cytotoxic T lymphocytes.
Journal of virology 2005;79(17):11239-46.
2005: Anders Wallensten; Vincent J Munster; Johan Elmberg; A D M E Osterhaus; Ron A M Fouchier; Björn Olsen
Multiple gene segment reassortment between Eurasian and American lineages of influenza A virus (H6N2) in Guillemot (Uria aalge).
Archives of virology 2005;150(8):1685-92.
2005: Guus F Rimmelzwaan; E G M Berkhoff; Nella J Nieuwkoop; Derek J Smith; Ron A M Fouchier; A D M E Osterhaus
Full restoration of viral fitness by multiple compensatory co-mutations in the nucleoprotein of influenza A virus cytotoxic T-lymphocyte escape mutants.
The Journal of general virology 2005;86(Pt 6):1801-5.
2005: Ron A M Fouchier; Thijs Kuiken; Guus F Rimmelzwaan; Albert Osterhaus
Global task force for influenza.
Nature 2005;435(7041):419-20.
2005: Ron A M Fouchier; Vincent J Munster; Anders Wallensten; Theo M Bestebroer; Sander Herfst; Derek Smith; Guus F Rimmelzwaan; Björn Olsen; Albert D M E Osterhaus
Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls.
Journal of virology 2005;79(5):2814-22.
2005: Roderick S Tang; Kutubuddin Mahmood; Mia M MacPhail; Jeanne M Guzzetta; Aurelia A Haller; Hui Liu; Jasmine Kaur; Heather A Lawlor; Elizabeth A Stillman; Jeanne H Schickli; Ron A M Fouchier; Albert D M E Osterhaus; Richard Spaete
A host-range restricted parainfluenza virus type 3 (PIV3) expressing the human metapneumovirus (hMPV) fusion protein elicits protective immunity in African green monkeys.
Vaccine 2005;23(14):1657-67.
2005: Juthatip Keawcharoen; Alongkorn Amonsin; Kanisak Oraveerakul; Sumitra Wattanodorn; T Papravasit; S Karnda; K Lekakul; R Pattanarangsan; Suwanna Noppornpanth; Ron A M Fouchier; A D M E Osterhaus; Sunchai Payungporn; Apiradee Theamboonlers; yong poovorawan
Characterization of the hemagglutinin and neuraminidase genes of recent influenza virus isolates from different avian species in Thailand.
Acta virologica 2005;49(4):277-80.
2004: Derek J Smith; Alan S Lapedes; Jan C de Jong; Theo M Bestebroer; Terry C Jones; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Mutations, drift, and the influenza archipelago.
Discovery medicine 2004;4(24):371-7.
2004: Juthatip Keawcharoen; Kanisak Oraveerakul; Thijs Kuiken; Ron A M Fouchier; Alongkorn Amonsin; Sunchai Payungporn; Suwanna Noppornpanth; Sumitra Wattanodorn; Apiradee Theambooniers; Rachod Tantilertcharoen; Rattapan Pattanarangsan; Nlin Arya; Parntep Ratanakorn; D M E Osterhaus; yong poovorawan
Avian influenza H5N1 in tigers and leopards.
Emerging infectious diseases 2004;10(12):2189-91.
2004: S A G Kemink; Ron A M Fouchier; F W Rozendaal; J M Broekman; Marion Koopmans; A D M E Osterhaus; P M Schneeberger
[A fatal infection due to avian influenza-A (H7N7) virus and adjustment of the preventive measures].
Nederlands tijdschrift voor geneeskunde 2004;148(44):2190-4.
2004: Thijs Kuiken; Guus F Rimmelzwaan; Debby van Riel; Geert van Amerongen; Marianne Baars; Ron A M Fouchier; Albert Osterhaus
Avian H5N1 influenza in cats.
Science (New York, N.Y.) 2004;306(5694):241.
2004: Guus F Rimmelzwaan; Jan C de Jong; Aad I M Bartelds; berry wilbrink; Ron A M Fouchier; A D M E Osterhaus
[The 2003/2004 influenza season in the Netherlands with a limited epidemic of the virus variant A/Fujian, and the vaccine composition for the 2004/2005 season].
Nederlands tijdschrift voor geneeskunde 2004;148(40):1984-8.
2004: Guus F Rimmelzwaan; E G M Berkhoff; Nella J Nieuwkoop; Ron A M Fouchier; A D M E Osterhaus
Functional compensation of a detrimental amino acid substitution in a cytotoxic-T-lymphocyte epitope of influenza a viruses by comutations.
Journal of virology 2004;78(16):8946-9.
2004: Sander Herfst; Miranda de Graaf; Jeanne H Schickli; Roderick S Tang; Jasmine Kaur; Chin-Fen Yang; Richard Spaete; Aurelia A Haller; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
Recovery of human metapneumovirus genetic lineages a and B from cloned cDNA.
Journal of virology 2004;78(15):8264-70.
2004: A D M E Osterhaus; Ron A M Fouchier; Thijs Kuiken
The aetiology of SARS: Koch's postulates fulfilled.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1447):1081-2.
2004: Guus F Rimmelzwaan; A C M Boon; Martina M Geelhoed-Mieras; J T M Voeten; Ron A M Fouchier; A D M E Osterhaus
Human airway epithelial cells present antigen to influenza virus-specific CD8+ CTL inefficiently after incubation with viral protein together with ISCOMATRIX.
Vaccine 2004;22(21-22):2769-75.
2004: Derek J Smith; Alan S Lapedes; Jan C de Jong; Theo M Bestebroer; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Mapping the antigenic and genetic evolution of influenza virus.
Science (New York, N.Y.) 2004;305(5682):371-6.
2004: Emmie de Wit; Monique I J Spronken; Theo M Bestebroer; Guus F Rimmelzwaan; Albert D M E Osterhaus; Ron A M Fouchier
Efficient generation and growth of influenza virus A/PR/8/34 from eight cDNA fragments.
Virus research 2004;103(1-2):155-61.
2004: Guus F Rimmelzwaan; A C M Boon; J T M Voeten; E G M Berkhoff; Ron A M Fouchier; A D M E Osterhaus
Sequence variation in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes.
Virus research 2004;103(1-2):97-100.
2004: Mia M MacPhail; Jeanne H Schickli; Roderick S Tang; Jasmine Kaur; Christopher L Robinson; Ron A M Fouchier; Albert D M E Osterhaus; Richard Spaete; Aurelia A Haller
Identification of small-animal and primate models for evaluation of vaccine candidates for human metapneumovirus (hMPV) and implications for hMPV vaccine design.
The Journal of general virology 2004;85(Pt 6):1655-63.
2004: Thijs Kuiken; Bernadette van den Hoogen; Debby van Riel; Jon D Laman; Geert van Amerongen; Leo Sprong; Ron A M Fouchier; Albert D M E Osterhaus
Experimental human metapneumovirus infection of cynomolgus macaques (Macaca fascicularis) results in virus replication in ciliated epithelial cells and pneumocytes with associated lesions throughout the respiratory tract.
The American journal of pathology 2004;164(6):1893-900.
2004: E G M Berkhoff; A C M Boon; Nella J Nieuwkoop; Ron A M Fouchier; Kees Sintnicolaas; A D M E Osterhaus; Guus F Rimmelzwaan
A mutation in the HLA-B*2705-restricted NP383-391 epitope affects the human influenza A virus-specific cytotoxic T-lymphocyte response in vitro.
Journal of virology 2004;78(10):5216-22.
2004: Ruth Manvell; Dick Gough; Nick Major; Ron A M Fouchier
Mortality in budgerigars associated with a reovirus-like agent.
The Veterinary record 2004;154(17):539-40.
2004: Ron A M Fouchier; Nico G Hartwig; Theo M Bestebroer; Berend Niemeyer; Jan C de Jong; James H Simon; Albert D M E Osterhaus
A previously undescribed coronavirus associated with respiratory disease in humans.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(16):6212-6.
2004: Bernadette van den Hoogen; Sander Herfst; Leo Sprong; Patricia A Cane; Eduardo Forleo-Neto; Rik de Swart; Albert D M E Osterhaus; Ron A M Fouchier
Antigenic and genetic variability of human metapneumoviruses.
Emerging infectious diseases 2004;10(4):658-66.
2004: A C M Boon; Gerrie de Mutsert; Ron A M Fouchier; Kees Sintnicolaas; Albert D M E Osterhaus; Guus F Rimmelzwaan
Preferential HLA usage in the influenza virus-specific CTL response.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4435-43.
2004: Jeroen Maertzdorf; Chiaoyin K Wang; Jennifer B Brown; Joseph D Quinto; Marla Chu; Miranda de Graaf; Bernadette van den Hoogen; Richard Spaete; Albert D M E Osterhaus; Ron A M Fouchier
Real-time reverse transcriptase PCR assay for detection of human metapneumoviruses from all known genetic lineages.
Journal of clinical microbiology 2004;42(3):981-6.
2004: Bart L Haagmans; Thijs Kuiken; Byron Martina; Ron A M Fouchier; Guus F Rimmelzwaan; Geert van Amerongen; Debby van Riel; Ton de Jong; Shigeyuki Itamura; Kwok-Hung Chan; Masato Tashiro; Albert D M E Osterhaus
Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques.
Nature medicine 2004;10(3):290-3.
2004: Marion Koopmans; berry wilbrink; Marina Conyn; Gerard Natrop; Hans van der Nat; Harry Vennema; Adam Meijer; Jim E Van Steenbergen; Ron A M Fouchier; Albert Osterhaus; Arnold Bosman
Transmission of H7N7 avian influenza A virus to human beings during a large outbreak in commercial poultry farms in the Netherlands.
Lancet 2004;363(9409):587-93.
2004: A C M Boon; Gerrie de Mutsert; Debbie Van Baarle; Derek J Smith; Alan S Lapedes; Ron A M Fouchier; Kees Sintnicolaas; Albert D M E Osterhaus; Guus F Rimmelzwaan
Recognition of homo- and heterosubtypic variants of influenza A viruses by human CD8+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2453-60.
2004: Ron A M Fouchier; Peter M Schneeberger; Frans W Rozendaal; Jan M Broekman; Stiena A G Kemink; Vincent J Munster; Thijs Kuiken; Guus F Rimmelzwaan; Martin Schutten; G J J van Doornum; Guus Koch; Arnold Bosman; Marion Koopmans; Albert D M E Osterhaus
Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1356-61.
2004: Jan C de Jong; Walter Emil Philipp Beyer; Guus F Rimmelzwaan; Ron A M Fouchier; Albert D M E Osterhaus
[Neuraminidase inhibitors oseltamivir and zanamivir: new means of defence against influenza].
Nederlands tijdschrift voor geneeskunde 2004;148(2):73-9.
2004: Ron A M Fouchier; Ab D M E Osterhaus
Laboratory tests for SARS: powerful or peripheral?
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2004;170(1):63-4.
2004: Bernadette van den Hoogen; D M E Osterhaus; Ron A M Fouchier
Clinical impact and diagnosis of human metapneumovirus infection.
The Pediatric infectious disease journal 2004;23(1 Suppl):S25-32.
2003: Thijs Kuiken; Ron A M Fouchier; Guus F Rimmelzwaan; Albert Osterhaus
Emerging viral infections in a rapidly changing world.
Current opinion in biotechnology 2003;14(6):641-6.
2003: Bernadette van den Hoogen; G J J van Doornum; John C Fockens; Jan J Cornelissen; Walter Emil Philipp Beyer; Ronald de Groot; Albert D M E Osterhaus; Ron A M Fouchier
Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients.
The Journal of infectious diseases 2003;188(10):1571-7.
2003: Byron Martina; Bart L Haagmans; Thijs Kuiken; Ron A M Fouchier; Guus F Rimmelzwaan; Geert van Amerongen; J S M Peiris; Wilina Lim; Albert D M E Osterhaus
Virology: SARS virus infection of cats and ferrets.
Nature 2003;425(6961):915.
2003: Jan C de Jong; Guus F Rimmelzwaan; Aad I M Bartelds; berry wilbrink; Ron A M Fouchier; Albert D M E Osterhaus
[The 2002/2003 influenza season in the Netherlands and the vaccine composition for the 2003/2004 season].
Nederlands tijdschrift voor geneeskunde 2003;147(40):1971-5.
2003: Roderick S Tang; Jeanne H Schickli; Mia M MacPhail; Fiona Fernandes; Leenas Bicha; Joshua Spaete; Ron A M Fouchier; Albert D M E Osterhaus; Richard Spaete; Aurelia A Haller
Effects of human metapneumovirus and respiratory syncytial virus antigen insertion in two 3' proximal genome positions of bovine/human parainfluenza virus type 3 on virus replication and immunogenicity.
Journal of virology 2003;77(20):10819-28.
2003: Thijs Kuiken; Ron A M Fouchier; Martin Schutten; Guus F Rimmelzwaan; Geert van Amerongen; Debby van Riel; Jon D Laman; Ton de Jong; G J J van Doornum; Wilina Lim; Ai Ee Ling; Paul K S Chan; John S Tam; Maria C Zambon; Robin Gopal; Christian Drosten; Sylvie van der Werf; Nicolas Escriou; Jean-Claude Manuguerra; Klaus Stöhr; J S M Peiris; Albert D M E Osterhaus
Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome.
Lancet 2003;362(9380):263-70.
2003: Ron A M Fouchier; Thijs Kuiken; Martin Schutten; Geert van Amerongen; G J J van Doornum; Bernadette van den Hoogen; Malik Peiris; Wilina Lim; Klaus Stöhr; Albert D M E Osterhaus
Aetiology: Koch's postulates fulfilled for SARS virus.
Nature 2003;423(6937):240.
2003: Christian Drosten; Stephan Günther; Wolfgang Preiser; Sylvie van der Werf; Hans-Reinhard Brodt; Stephan Becker; Holger Rabenau; Marcus Panning; Larissa Kolesnikova; Ron A M Fouchier; Annemarie Berger; Ana-Maria Burguière; Jindrich Cinatl; Markus Eickmann; Nicolas Escriou; Klaus Grywna; Stefanie Kramme; Jean-Claude Manuguerra; Stefanie Müller; Volker Rickerts; Martin Stürmer; Simon Vieth; Hans-Dieter Klenk; Albert D M E Osterhaus; Herbert Schmitz; Hans Wilhelm Doerr
Identification of a novel coronavirus in patients with severe acute respiratory syndrome.
The New England journal of medicine 2003;348(20):1967-76.
2003: Ron A M Fouchier; Albert D M E Osterhaus; Ian H Brown
Animal influenza virus surveillance.
Vaccine 2003;21(16):1754-7.
2003: Ab Osterhaus; Ron A M Fouchier
Human metapneumovirus in the community.
Lancet 2003;361(9361):890-1.
2003: Guus F Rimmelzwaan; Thijs Kuiken; Geert van Amerongen; Theo M Bestebroer; Ron A M Fouchier; A D M E Osterhaus
A primate model to study the pathogenesis of influenza A (H5N1) virus infection.
Avian diseases 2003;47(3 Suppl):931-3.
2003: Ron A M Fouchier; Björn Olsen; Theo M Bestebroer; Sander Herfst; L van der Kemp; Guus F Rimmelzwaan; A D M E Osterhaus
Influenza A virus surveillance in wild birds in Northern Europe in 1999 and 2000.
Avian diseases 2003;47(3 Suppl):857-60.
2002: Guus F Rimmelzwaan; Jan C de Jong; Aad I M Bartelds; berry wilbrink; Ron A M Fouchier; A D M E Osterhaus
[The 2001/2002 influenza season and the vaccine composition for the 2002/2003 season].
Nederlands tijdschrift voor geneeskunde 2002;146(39):1846-50.
2002: A C M Boon; E Fringuelli; Y M F Graus; Ron A M Fouchier; Kees Sintnicolaas; Alfonso Iorio; Guus F Rimmelzwaan; A D M E Osterhaus
Influenza A virus specific T cell immunity in humans during aging.
Virology 2002;299(1):100-8.
2002: Bernadette van den Hoogen; Theo M Bestebroer; Albert D M E Osterhaus; Ron A M Fouchier
Analysis of the genomic sequence of a human metapneumovirus.
Virology 2002;295(1):119-32.
2002: A C M Boon; Gerrie de Mutsert; Y M F Graus; Ron A M Fouchier; Kees Sintnicolaas; A D M E Osterhaus; Guus F Rimmelzwaan
Sequence variation in a newly identified HLA-B35-restricted epitope in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes.
Journal of virology 2002;76(5):2567-72.
2002: A C M Boon; Gerrie de Mutsert; Y M F Graus; Ron A M Fouchier; Kees Sintnicolaas; A D M E Osterhaus; Guus F Rimmelzwaan
The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype.
Journal of virology 2002;76(2):582-90.
2001: Jan C de Jong; Guus F Rimmelzwaan; Aad I M Bartelds; berry wilbrink; Ron A M Fouchier; Albert D M E Osterhaus
[2000/01 influenza season and the vaccine composition for the season 2001/'02].
Nederlands tijdschrift voor geneeskunde 2001;145(40):1945-50.
2001: J T M Voeten; Guus F Rimmelzwaan; Nella J Nieuwkoop; Ron A M Fouchier; Albert D M E Osterhaus
Antigen processing for MHC class I restricted presentation of exogenous influenza A virus nucleoprotein by B-lymphoblastoid cells.
Clinical and experimental immunology 2001;125(3):423-31.
2001: Jan C de Jong; Paul P Heinen; W L A Loeffen; AP van Nieuwstadt; E C Claas; Theo M Bestebroer; K Bijlsma; C Verweij; Albert D M E Osterhaus; Guus F Rimmelzwaan; Ron A M Fouchier; Tjeerd G Kimman
Antigenic and molecular heterogeneity in recent swine influenza A(H1N1) virus isolates with possible implications for vaccination policy.
Vaccine 2001;19(31):4452-64.
2001: Guus F Rimmelzwaan; Thijs Kuiken; Geert van Amerongen; Theo M Bestebroer; Ron A M Fouchier; Albert D M E Osterhaus
Pathogenesis of influenza A (H5N1) virus infection in a primate model.
Journal of virology 2001;75(14):6687-91.
2001: Bernadette van den Hoogen; J C de Jong; Jan Groen; Thijs Kuiken; Ronald de Groot; Ron A M Fouchier; Albert D M E Osterhaus
A newly discovered human pneumovirus isolated from young children with respiratory tract disease.
Nature medicine 2001;7(6):719-24.
2001: Guus F Rimmelzwaan; Jan C de Jong; Theo M Bestebroer; Anton M van Loon; E C Claas; Ron A M Fouchier; Albert D M E Osterhaus
Antigenic and genetic characterization of swine influenza A (H1N1) viruses isolated from pneumonia patients in The Netherlands.
Virology 2001;282(2):301-6.
2000: Ron A M Fouchier; Theo M Bestebroer; Sander Herfst; L Van Der Kemp; Guus F Rimmelzwaan; Albert D M E Osterhaus
Detection of influenza A viruses from different species by PCR amplification of conserved sequences in the matrix gene.
Journal of clinical microbiology 2000;38(11):4096-101.
2000: J T M Voeten; Theo M Bestebroer; Nella J Nieuwkoop; Ron A M Fouchier; Albert D M E Osterhaus; Guus F Rimmelzwaan
Antigenic drift in the influenza A virus (H3N2) nucleoprotein and escape from recognition by cytotoxic T lymphocytes.
Journal of virology 2000;74(15):6800-7.
2000: Albert D M E Osterhaus; Guus F Rimmelzwaan; Byron Martina; Theo M Bestebroer; Ron A M Fouchier
Influenza B virus in seals.
Science (New York, N.Y.) 2000;288(5468):1051-3.
2000: Jan C de Jong; Guus F Rimmelzwaan; Ron A M Fouchier; Albert D M E Osterhaus
Influenza virus: a master of metamorphosis.
The Journal of infection 2000;40(3):218-28.
1999: Guus F Rimmelzwaan; Marianne Baars; P de Lijster; Ron A M Fouchier; Albert D M E Osterhaus
Inhibition of influenza virus replication by nitric oxide.
Journal of virology 1999;73(10):8880-3.