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William Foulkes

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Nassim Taherian; David E Goldgar; Nancy Hamel; Louis R Bégin; Tarek A Bismar; Bing-Jian Feng; William D Foulkes
Familial prostate cancer: the damage done and lessons learnt.
Nelly Sabbaghian; Andrew Y Shuen; Marc Tischkowitz; Amin Bahubeshi; Peter A Kanetsky; Katherine L Nathanson; William D Foulkes
Germ-line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours.
Jian Zhang; Yuhao Shi; Luca Cavallone; Alex Ferenczy; William D Foulkes; Walter H Gotlieb; Emilie Lalonde; Lili Li; Jacek Majewski
Exome profiling of primary, metastatic and recurrent ovarian carcinomas in a BRCA1-positive patient.

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2013: Nassim Taherian; David E Goldgar; Nancy Hamel; Louis R Bégin; Tarek A Bismar; Bing-Jian Feng; William D Foulkes
Familial prostate cancer: the damage done and lessons learnt.
Nature reviews. Urology 2013;10(2):116-22.
2013: Nelly Sabbaghian; Andrew Y Shuen; Marc Tischkowitz; Amin Bahubeshi; Peter A Kanetsky; Katherine L Nathanson; William D Foulkes
Germ-line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours.
BMC research notes 2013;6():127.
2013: Jian Zhang; Yuhao Shi; Luca Cavallone; Alex Ferenczy; William D Foulkes; Walter H Gotlieb; Emilie Lalonde; Lili Li; Jacek Majewski
Exome profiling of primary, metastatic and recurrent ovarian carcinomas in a BRCA1-positive patient.
BMC cancer 2013;13():146.
2013: Marc Tischkowitz; William D Foulkes; Nancy Hamel; Anne-Marie Mes-Masson; Carly Pouchet; Diane Provencher; Nelly Sabbaghian; Patricia N Tonin
Contribution of the PALB2 c.2323C>T [p.Q775X] founder mutation in well-defined breast and/or ovarian cancer families and unselected ovarian cancer cases of French Canadian descent.
BMC medical genetics 2013;14():5.
2012: Nelly Sabbaghian; Archana Srivastava; Steffen Albrecht; Nancy Hamel; John R Priest; William D Foulkes
Germline DICER1 mutation and associated loss of heterozygosity in a pineoblastoma.
Journal of medical genetics 2012;49(7):417-9.
2012: Jacob McGee; Steven A Narod; Barry Rosen; Leigha Senter; Ping Sun; Nadine Tung; Peter Ainsworth; Andrea Eisen; William D Foulkes; Parviz Ghadirian; Beth Karlan; Charmaine Kim-Sing; Joanne Kotsopoulos; Jan Lubinski; Henry T Lynch
Anthropometric measures and risk of ovarian cancer among BRCA1 and BRCA2 mutation carriers.
Obesity (Silver Spring, Md.) 2012;20(6):1288-92.
2012: Jarle Arnes; Jan P Baak; William D Foulkes; Per E Lønning; Ingunn M Stefansson; Oddbjørn Straume; Lars A Akslen
Vascular proliferation is a prognostic factor in breast cancer.
Breast cancer research and treatment 2012;133(2):501-10.
2012: William D Foulkes
Epigenetic modification and cancer: mark or stamp?
Endocrine-related cancer 2012;19(2):C23-7.
2012: Marc Tischkowitz; Maxime P Vallée; Jonine L Bernstein; Leslie Bernstein; Marinela Capanu; Patrick Concannon; William D Foulkes; Lili Li; Xiaolin Liang; Nelly Sabbaghian; Sean V Tavtigian; Colin B Begg
Rare germline mutations in PALB2 and breast cancer risk: a population-based study.
Human mutation 2012;33(4):674-80.
2012: Julia H Appleby-Tagoe; William D Foulkes; Laura Palma
Reading between the lines: a comparison of responders and non-responders to a family history questionnaire and implications for cancer genetic counselling.
Journal of genetic counseling 2012;21(2):273-91.
2011: William D Foulkes; Richard P Frieder; Nicole Graf; Nancy Hamel; Barbara Pasini; Nelly Sabbaghian; Archana Srivastava; Marc Tischkowitz; Robert H Young; Jocelyne Arseneau; Sofia Asioli; Amin Bahubeshi; Gareth Baynam; Dorothée Bouron-Dal Soglio; Adrian Charles; Catherine S Choong; Megan K Dishop; Mesiha Ekim; John R Priest
Extending the phenotypes associated with DICER1 mutations.
Human mutation 2011;32(12):1381-4.
2011: Hawa Nalwoga; Ingunn M Stefansson; Henry Wabinga; Jarle Arnes; William D Foulkes; Lars A Akslen
Vascular proliferation is increased in basal-like breast cancer.
Breast cancer research and treatment 2011;130(3):1063-71.
2011: Amin Bahubeshi; Marc Tischkowitz; William D Foulkes
miRNA processing and human cancer: DICER1 cuts the mustard.
Science translational medicine 2011;3(111):111ps46.
2011: Deidra J Osher; Yaël B Kushner; Jocelyne Arseneau; William D Foulkes
Melphalan as a treatment for BRCA-related ovarian carcinoma: can you teach an old drug new tricks?
Journal of clinical pathology 2011;64(10):924-6.
2011: J Vijai; T Lencz; K Offit; Saurav Guha; William D Foulkes; D Gallagher; S Guha; N Hamel; Tomas Kirchhoff; R J Klein
Genetic architecture of prostate cancer in the Ashkenazi Jewish population.
British journal of cancer 2011;105(6):864-9.
2011: Zsofia Kinga Stadler; Liying Zhang; William D Foulkes; Robert Kurtz; Kenneth Offit; Sara H Olson; Mark Robson; Nelly Sabbaghian; Erin Salo-Mullen; Jennifer A Simon; Marc Tischkowitz
Germline PALB2 mutation analysis in breast-pancreas cancer families.
Journal of medical genetics 2011;48(8):523-5.
2011: Kristi Baker; Tarek A Bismar; Jonathan Lachapelle; Luigi Terracciano; Inti Zlobec; William D Foulkes
Prognostic significance of CD8+ T lymphocytes in breast cancer depends upon both oestrogen receptor status and histological grade.
Histopathology 2011;58(7):1107-16.
2011: Ellen Warner; Kimberley Hill; Petrina Causer; Donald Plewes; Roberta Jong; Martin Yaffe; William D Foulkes; Parviz Ghadirian; Henry Lynch; Fergus Couch; John Wong; Frances Wright; Ping Sun; Steven A Narod
Prospective study of breast cancer incidence in women with a BRCA1 or BRCA2 mutation under surveillance with and without magnetic resonance imaging.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(13):1664-9.
2011: Kelly Metcalfe; Henry T Lynch; Parviz Ghadirian; Nadine Tung; Charmaine Kim-Sing; Olufunmilayo I Olopade; Susan M Domchek; Andrea Eisen; William D Foulkes; Barry Rosen; Danny Vesprini; Ping Sun; Steven A Narod
Risk of ipsilateral breast cancer in BRCA1 and BRCA2 mutation carriers.
Breast cancer research and treatment 2011;127(1):287-96.
2011: Kelly A Metcalfe; S Gershman; Henry T Lynch; Parviz Ghadirian; N Tung; Charmaine Kim-Sing; Olufunmilayo I Olopade; Susan M Domchek; J McLennan; A Eisen; William D Foulkes; Barry Rosen; Ping Sun; Steven A Narod
Predictors of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.
British journal of cancer 2011;104(9):1384-92.
2011: S Bernatsky; R Ramsey-Goldman; William D Foulkes; C Gordon; A E Clarke
Breast, ovarian, and endometrial malignancies in systemic lupus erythematosus: a meta-analysis.
British journal of cancer 2011;104(9):1478-81.
2011: Andrew Y Shuen; William D Foulkes
Inherited mutations in breast cancer genes--risk and response.
Journal of mammary gland biology and neoplasia 2011;16(1):3-15.
2011: Thomas Rio Frio; Amin Bahubeshi; Chryssa Kanellopoulou; Nancy Hamel; Marek Niedziela; Nelly Sabbaghian; Carly Pouchet; Lucy Gilbert; Paul K O'Brien; Kim Serfas; Peter Broderick; Richard S Houlston; Fabienne Lesueur; Elena Bonora; Stefan Muljo; R Neil Schimke; Dorothée Bouron-Dal Soglio; Jocelyne Arseneau; Kris Ann Pinekenstein Schultz; John R Priest; Van Hung Nguyen; H Rubén Harach; David M Livingston; William D Foulkes; Marc Tischkowitz
DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors.
JAMA : the journal of the American Medical Association 2011;305(1):68-77.
2011: Kevin C H Ha; Jarle Hakas; Iwanka Kozarewa; Emilie Lalonde; Maryou B K Lambros; Lili Li; Chris J Lord; Jacek Majewski; Costas Mitsopoulos; Rachael Natrajan; Jorge S Reis-Filho; Anne Vincent-Salomon; Alan Ashworth; Mark Basik; Luca Cavallone; Kerry Fenwick; William D Foulkes
Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines.
BMC medical genomics 2011;4():75.
2011: Clarissa Allen; William D Foulkes
Qualitative thematic analysis of consent forms used in cancer genome sequencing.
BMC medical ethics 2011;12():14.
2010: Thomas Rio Frio; Josée Lavoie; Nancy Hamel; Felipe C Geyer; Yaël B Kushner; David J Novak; Landon Wark; Cristian Capelli; Jorge S Reis-Filho; Sabine Mai; Tomi Pastinen; Marc D Tischkowitz; Victoria A Marcus; William D Foulkes
Homozygous BUB1B mutation and susceptibility to gastrointestinal neoplasia.
The New England journal of medicine 2010;363(27):2628-37.
2010: Sebastien Levesque; Najma Ahmed; Van Hung Nguyen; Ayoub Nahal; Miriam Blumenkrantz; Pramod Puligandla; George Chong; William D Foulkes
Neonatal Gardner fibroma: a sentinel presentation of severe familial adenomatous polyposis.
Pediatrics 2010;126(6):e1599-602.
2010: Amin Bahubeshi; Nebil Bal; Thomas Rio Frio; Nancy Hamel; Carly Pouchet; Ahmet Yilmaz; Dorothée Bouron-Dal Soglio; Gretchen M Williams; Marc Tischkowitz; John R Priest; William D Foulkes
Germline DICER1 mutations and familial cystic nephroma.
Journal of medical genetics 2010;47(12):863-6.
2010: Thomas Rio Frio; Maria Haanpää; Carly Pouchet; Katri Pylkäs; Mikko Vuorela; Marc Tischkowitz; Robert Winqvist; William D Foulkes
Mutation analysis of the gene encoding the PALB2-binding protein MRG15 in BRCA1/2-negative breast cancer families.
Journal of human genetics 2010;55(12):842-3.
2010: Ophira M Ginsburg; Charmaine Kim-Sing; William D Foulkes; Parviz Ghadirian; Henry T Lynch; Ping Sun; Steven A Narod
BRCA1 and BRCA2 families and the risk of skin cancer.
Familial cancer 2010;9(4):489-93.
2010: William D Foulkes; Ian P M Tomlinson
Are we there yet?: journeying along the cancer genetic information superhighway.
Current opinion in genetics & development 2010;20(3):197-200.
2010: William D Foulkes; Jorge S Reis-Filho; Steven A Narod
Tumor size and survival in breast cancer--a reappraisal.
Nature reviews. Clinical oncology 2010;7(6):348-53.
2010: Jonathan Lachapelle; Lucy Gilbert; Giovanni Artho; Thierry Alcindor; Ramila Amre; Jocelyne Arseneau; William D Foulkes
Colonic or coelomic?
Lancet 2010;375(9728):1844.
2010: William D Foulkes
Traffic control for BRCA1.
The New England journal of medicine 2010;362(8):755-6.
2010: Melissa C Southey; Zhi L Teo; James G Dowty; Fabrice A Odefrey; Daniel J Park; Marc Tischkowitz; Nelly Sabbaghian; Carmel Apicella; Graham B Byrnes; Ingrid Winship; Laura Baglietto; Graham G Giles; David E Goldgar; William D Foulkes; John L Hopper
A PALB2 mutation associated with high risk of breast cancer.
Breast cancer research : BCR 2010;12(6):R109.
2010: Mohammad R Akbari; Patricia Tonin; William D Foulkes; Parviz Ghadirian; Marc Tischkowitz; Steven A Narod
RAD51C germline mutations in breast and ovarian cancer patients.
Breast cancer research : BCR 2010;12(4):404.
2010: Celia M T Greenwood; Shuying Sun; Justin Veenstra; Nancy Hamel; Bethany Niell; Stephen B Gruber; William D Foulkes
How old is this mutation? - a study of three Ashkenazi Jewish founder mutations.
BMC genetics 2010;11():39.
2009: Parviz Ghadirian; André Robidoux; P Zhang; R Royer; M Akbari; S Zhang; E Fafard; M Costa; G Martin; C Potvin; E Patocskai; N Larouche; R Younan; E Nassif; Sylvie Giroux; Steven A Narod; Francois Rousseau; William D Foulkes
The contribution of founder mutations to early-onset breast cancer in French-Canadian women.
Clinical genetics 2009;76(5):421-6.
2009: Lili Li; Kajal Biswas; Laura Anne Habib; Sergey G Kuznetsov; Nancy Hamel; Tomas Kirchhoff; Nora Wong; Susan Armel; George Chong; Steven A Narod; Kathleen Claes; Kenneth Offit; Mark Robson; Stacey Stauffer; Shyam K Sharan; William D Foulkes
Functional redundancy of exon 12 of BRCA2 revealed by a comprehensive analysis of the c.6853A>G (p.I2285V) variant.
Human mutation 2009;30(11):1543-50.
2009: Marc D Tischkowitz; Nelly Sabbaghian; Nancy Hamel; Ayelet Borgida; Chaim Rosner; Nassim Taherian; Archana Srivastava; Spring Holter; Heidi Rothenmund; Parviz Ghadirian; William D Foulkes; Steven Gallinger
Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer.
Gastroenterology 2009;137(3):1183-6.
2009: David J Novak; Nelly Sabbaghian; Philippe Maillet; Pierre O Chappuis; William D Foulkes; Marc Tischkowitz
Analysis of the genes coding for the BRCA1-interacting proteins, RAP80 and Abraxas (CCDC98), in high-risk, non-BRCA1/2, multiethnic breast cancer cases.
Breast cancer research and treatment 2009;117(2):453-9.
2009: William D Foulkes; Matthew J Grainge; Emad A Rakha; Andrew R Green; Ian O Ellis
Tumor size is an unreliable predictor of prognosis in basal-like breast cancers and does not correlate closely with lymph node status.
Breast cancer research and treatment 2009;117(1):199-204.
2009: Fleur Huang; Yael B Kushner; Adrian Langleben; William D Foulkes
Eleven years disease-free: role of chemotherapy in metastatic BRCA2-related breast cancer.
Nature reviews. Clinical oncology 2009;6(8):488-92.
2009: Jarle Arnes; Louis R Bégin; Ingunn M Stefansson; Jean-Sebastien Brunet; T O Nielsen; William D Foulkes; Lars A Akslen
Expression of epidermal growth factor receptor in relation to BRCA1 status, basal-like markers and prognosis in breast cancer.
Journal of clinical pathology 2009;62(2):139-46.
2009: Kristi Baker; William D Foulkes; Jeremy R Jass
MSI-H colorectal cancers preferentially retain and expand intraepithelial lymphocytes rather than peripherally derived CD8+ T cells.
Cancer immunology, immunotherapy : CII 2009;58(1):135-44.
2008: Laura Palma; Victoria A Marcus; Lucy Gilbert; George Chong; William D Foulkes
Synchronous occult cancers of the endometrium and fallopian tube in an MSH2 mutation carrier at time of prophylactic surgery.
Gynecologic oncology 2008;111(3):575-8.
2008: Joanne Kotsopoulos; Clifford L Librach; Jan Lubinski; Jacek Gronwald; Charmaine Kim-Sing; Parviz Ghadirian; Henry T Lynch; Pal Moller; William D Foulkes; Susan Randall; Siranoush Manoukian; Barbara Pasini; Nadine Tung; Peter Ainsworth; Shelly Cummings; Ping Sun; Steven A Narod
Infertility, treatment of infertility, and the risk of breast cancer among women with BRCA1 and BRCA2 mutations: a case-control study.
Cancer causes & control : CCC 2008;19(10):1111-9.
2008: William D Foulkes
Inherited susceptibility to common cancers.
The New England journal of medicine 2008;359(20):2143-53.
2008: Marc S Greenblatt; Lawrence C Brody; William D Foulkes; Maurizio Genuardi; Robert M W Hofstra; Magali Olivier; Sharon E Plon; Rolf Sijmons; Olga Sinilnikova; Amanda B Spurdle
Locus-specific databases and recommendations to strengthen their contribution to the classification of variants in cancer susceptibility genes.
Human mutation 2008;29(11):1273-81.
2008: Marc D Tischkowitz; Ahmet Yilmaz; Long Q Chen; Danielle M Karyadi; David Novak; Tomas Kirchhoff; Nancy Hamel; Sean V Tavtigian; Suzanne Kolb; Tarek A Bismar; Raquel Aloyz; Peter S Nelson; Lee Hood; Steven A Narod; Kirsten A White; Elaine A Ostrander; William B Isaacs; Kenneth Offit; Kathleen Cooney; Janet L Stanford; William D Foulkes
Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer.
Cancer letters 2008;270(1):173-80.
2008: Philippe Campeau; William D Foulkes; Marc Tischkowitz
Hereditary breast cancer: new genetic developments, new therapeutic avenues.
Human genetics 2008;124(1):31-42.
2008: Steven A Narod; Susan L Neuhausen; G Vichodez; S Armel; Henry T Lynch; Parviz Ghadirian; S Cummings; Olufunmilayo I Olopade; D Stoppa-Lyonnet; Fergus J. Couch; T Wagner; Ellen Warner; William D Foulkes; Howard M Saal; Jeffrey N Weitzel; A Tulman; A Poll; R Nam; P Sun; Jessica Danquah; Susan Domchek; Nadine Tung; Peter Ainsworth; Douglas Horsman; Charmaine Kim-Sing; Christine Maugard; Andrea Eisen; Mary Daly; Wendy McKinnon; Marie Wood; Claudine Isaacs; Dawna Gilchrist; Beth Y Karlan; Raluca Nedelcu; Wendy Meschino; Judy Garber; Barbara Pasini; Siranoush Manoukian; Christina Bellati
Rapid progression of prostate cancer in men with a BRCA2 mutation.
British journal of cancer 2008;99(2):371-4.
2008: Marc Tischkowitz; Nancy Hamel; Marcelo A Carvalho; Gabriel Birrane; Aditi Soni; erik van beers; Simon A Joosse; Nora Wong; David Novak; Louise A Quenneville; Scott Grist; petra nederlof; David E Goldgar; Sean V Tavtigian; Alvaro Monteiro; John A A Ladias; William D Foulkes
Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
European journal of human genetics : EJHG 2008;16(7):820-32.
2008: Kelly A Metcalfe; William D Foulkes; Charmaine Kim-Sing; P Ainsworth; Barry Rosen; S Armel; A Poll; Andrea Eisen; D Gilchrist; A Chudley; Parviz Ghadirian; C Maugard; E G Lemire; Ping Sun; Steven A Narod
Family history as a predictor of uptake of cancer preventive procedures by women with a BRCA1 or BRCA2 mutation.
Clinical genetics 2008;73(5):474-9.
2008: Marc Tischkowitz; Nelly Sabbaghian; Anna M Ray; Ethan M Lange; William D Foulkes; Kathleen Cooney
Analysis of the gene coding for the BRCA2-interacting protein PALB2 in hereditary prostate cancer.
The Prostate 2008;68(6):675-8.
2008: Kelly A Metcalfe; Daphna Birenbaum-Carmeli; Jan Lubinski; Jacek Gronwald; Henry Lynch; Pal Moller; Parviz Ghadirian; William D Foulkes; Jan Klijn; Eitan Friedman; Charmaine Kim-Sing; Peter Ainsworth; Barry Rosen; Susan M Domchek; Teresa Wagner; Nadine Tung; Siranoush Manoukian; Fergus J. Couch; Ping Sun; Steven A Narod
International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers.
International journal of cancer. Journal international du cancer 2008;122(9):2017-22.
2008: Suzanna L Arcand; Christine M Maugard; Parviz Ghadirian; André Robidoux; Chantal Perret; Phil Zhang; Eve Fafard; Anne-Marie Mes-Masson; William D Foulkes; Diane Provencher; Steven A Narod; Patricia N Tonin
Germline TP53 mutations in BRCA1 and BRCA2 mutation-negative French Canadian breast cancer families.
Breast cancer research and treatment 2008;108(3):399-408.
2008: Kelly A Metcalfe; Jan Lubinski; Parviz Ghadirian; Henry Lynch; Charmaine Kim-Sing; Eitan Friedman; William D Foulkes; Susan M Domchek; Peter Ainsworth; Claudine Isaacs; Nadine Tung; Jacek Gronwald; Shelly Cummings; Teresa Wagner; Siranoush Manoukian; Pål Møller; Jeffrey N Weitzel; Ping Sun; Steven A Narod
Predictors of contralateral prophylactic mastectomy in women with a BRCA1 or BRCA2 mutation: the Hereditary Breast Cancer Clinical Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(7):1093-7.
2008: Thien-Tuong-Vi Vu; Anthony G Zeitouni; Pantelis Tsinalis; William D Foulkes; Abdulrahman Hagr
Familial clustering of parotid gland lymphoepithelioma in North America.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 2008;37(1):23-6.
2008: David J Novak; Long Qi Chen; Parviz Ghadirian; Nancy Hamel; Phil Zhang; Vanessa Rossiny; Guy Cardinal; André Robidoux; Patricia N Tonin; Francois Rousseau; Steven A Narod; William D Foulkes
Identification of a novel CHEK2 variant and assessment of its contribution to the risk of breast cancer in French Canadian women.
BMC cancer 2008;8():239.
2008: William D Foulkes
BRCA1--sowing the seeds crooked in the furrow.
Nature genetics 2008;40(1):8-9.
2007: William D Foulkes
p53--master and commander.
The New England journal of medicine 2007;357(25):2539-41.
2007: William D Foulkes
Clinically relevant biology of hereditary breast cancer.
Seminars in oncology 2007;34(5):379-83.
2007: Amber Yasmeen; Tarek A Bismar; Kandouz Mustapha; William D Foulkes; Pierre-Yves Desprez; Ala-Eddin Al Moustafa
E6/E7 of HPV type 16 promotes cell invasion and metastasis of human breast cancer cells.
Cell cycle (Georgetown, Tex.) 2007;6(16):2038-42.
2007: Carmel Apicella; James G Dowty; Gillian S Dite; Mark A Jenkins; Ruby T Senie; Mary B Daly; Irene L Andrulis; Esther M John; Saundra S Buys; Frederick P Li; Gord Glendon; Wendy Chung; Hilmi Ozcelik; alexander miron; K Kotar; Melissa C Southey; William D Foulkes; John L Hopper
Validation study of the LAMBDA model for predicting the BRCA1 or BRCA2 mutation carrier status of North American Ashkenazi Jewish women.
Clinical genetics 2007;72(2):87-97.
2007: Benoît Mesurolle; Laurence Kadoch; Mona El-Khoury; André Lisbona; Nandini Dendukuri; William D Foulkes
Sonographic features of breast carcinoma presenting as masses in BRCA gene mutation carriers.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2007;26(6):817-24.
2007: Marc Tischkowitz; Bing Xia; Nelly Sabbaghian; Jorge S Reis-Filho; Nancy Hamel; Guilan Li; erik van beers; Lili Li; Tayma Khalil; Louise A Quenneville; Atilla Omeroglu; Aletta Poll; Pierre Lepage; Nora Wong; petra nederlof; Alan Ashworth; Patricia N Tonin; Steven A Narod; David M Livingston; William D Foulkes
Analysis of PALB2/FANCN-associated breast cancer families.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(16):6788-93.
2007: Nancy Hamel; Nora Wong; Lesley Alpert; Maria Galvez; William D Foulkes
Mixed ovarian germ cell tumor in a BRCA2 mutation carrier.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2007;26(2):160-4.
2007: Munir Al Refae; Nora Wong; François Patenaude; Louis R Bégin; William D Foulkes
Hereditary leiomyomatosis and renal cell cancer: an unusual and aggressive form of hereditary renal carcinoma.
Nature clinical practice. Oncology 2007;4(4):256-61.
2007: William D Foulkes; Parviz Ghadirian; Mohammed Reza Akbari; Nancy Hamel; Sylvie Giroux; Nelly Sabbaghian; Andrew Darnel; Robert Royer; Aletta Poll; Eve Fafard; André Robidoux; Ginette Martin; Tarek A Bismar; Marc Tischkowitz; Francois Rousseau; Steven A Narod
Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women.
Breast cancer research : BCR 2007;9(6):R83.
2007: Marc Tischkowitz; Jean-Sebastien Brunet; Louis R Bégin; David G Huntsman; Mary Cheang; Lars A Akslen; Torsten O Nielsen; William D Foulkes
Use of immunohistochemical markers can refine prognosis in triple negative breast cancer.
BMC cancer 2007;7():134.
2007: John R McLaughlin; Harvey A Risch; Jan Lubinski; Pal Moller; Parviz Ghadirian; Henry T Lynch; Beth Y Karlan; David Fishman; Barry Rosen; Susan L Neuhausen; Kenneth Offit; Noah D Kauff; Susan M Domchek; Nadine Tung; Eitan Friedman; William D Foulkes; Ping Sun; Steven A Narod
Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study.
The lancet oncology 2007;8(1):26-34.
2006: Kristi Baker; George Chong; William D Foulkes; Jeremy R Jass
Transforming growth factor-beta pathway disruption and infiltration of colorectal cancers by intraepithelial lymphocytes.
Histopathology 2006;49(4):371-80.
2006: Kathleen K Oros; Parviz Ghadirian; Christine M Maugard; Chantal Perret; Yosabeth Paredes; Anne-Marie Mes-Masson; William D Foulkes; Diane Provencher; Patricia N Tonin
Application of BRCA1 and BRCA2 mutation carrier prediction models in breast and/or ovarian cancer families of French Canadian descent.
Clinical genetics 2006;70(4):320-9.
2006: Eiji Shinto; Kristi Baker; Hitoshi Tsuda; Hidetaka Mochizuki; Hideki Ueno; Osamu Matsubara; William D Foulkes; Jeremy R Jass
Tumor buds show reduced expression of laminin-5 gamma 2 chain in DNA mismatch repair deficient colorectal cancer.
Diseases of the colon and rectum 2006;49(8):1193-202.
2006: Amy Finch; Mario E Beiner; Jan Lubinski; Henry T Lynch; Pal Moller; Barry Rosen; Joan Murphy; Parviz Ghadirian; Eitan Friedman; William D Foulkes; Charmaine Kim-Sing; Teresa Wagner; Nadine Tung; Fergus J. Couch; Dominique Stoppa-Lyonnet; Peter Ainsworth; Mary Daly; Barbara Pasini; Ruth Gershoni-Baruch; Charis Eng; Olufunmilayo I Olopade; Jane McLennan; Beth Y Karlan; Jeffrey N Weitzel; Ping Sun; Steven A Narod
Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation.
JAMA : the journal of the American Medical Association 2006;296(2):185-92.
2006: P Galiatsatos; Lidia Kasprzak; George Chong; J R Jass; William D Foulkes
Multiple primary malignancies in a patient with situs ambiguus.
Clinical genetics 2006;69(6):528-31.
2006: Marc Tischkowitz; William D Foulkes
The basal phenotype of BRCA1-related breast cancer: past, present and future.
Cell cycle (Georgetown, Tex.) 2006;5(9):963-7.
2006: Rashmi Goswami; Parham Minoo; Kristi Baker; George Chong; William D Foulkes; Jeremy R Jass
Hyperplastic polyposis and cancer of the colon with gastrinoma of the duodenum.
Nature clinical practice. Oncology 2006;3(5):281-4; quiz 285.
2006: Steven A Narod; Jan Lubinski; Parviz Ghadirian; Henry T Lynch; Pal Moller; William D Foulkes; Barry Rosen; Charmaine Kim-Sing; Claudine Isaacs; Susan M Domchek; Susan Domcheck; Ping Sun
Screening mammography and risk of breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study.
The lancet oncology 2006;7(5):402-6.
2006: Jacek Gronwald; Nadine Tung; William D Foulkes; Kenneth Offit; Ruth Gershoni; Mary Daly; Charmaine Kim-Sing; Håkan Olsson; Peter Ainsworth; Andrea Eisen; Howard M Saal; Eitan Friedman; Olufunmilayo I Olopade; Michael Osborne; Jeffrey N Weitzel; Henry T Lynch; Parviz Ghadirian; Jan Lubinski; Ping Sun; Steven A Narod
Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: an update.
International journal of cancer. Journal international du cancer 2006;118(9):2281-4.
2006: Lili Li; Susan McVety; Rami Younan; Ping Liang; Desirée Du Sart; Philip H Gordon; Pierre Hutter; Frans B L Hogervorst; George Chong; William D Foulkes
Distinct patterns of germ-line deletions in MLH1 and MSH2: the implication of Alu repetitive element in the genetic etiology of Lynch syndrome (HNPCC).
Human mutation 2006;27(4):388.
2006: Polymnia Galiatsatos; William D Foulkes
Familial adenomatous polyposis.
The American journal of gastroenterology 2006;101(2):385-98.
2006: Susan McVety; Lili Li; Philip H Gordon; George Chong; William D Foulkes
Disruption of an exon splicing enhancer in exon 3 of MLH1 is the cause of HNPCC in a Quebec family.
Journal of medical genetics 2006;43(2):153-6.
2006: William D Foulkes
BRCA1 and BRCA2: chemosensitivity, treatment outcomes and prognosis.
Familial cancer 2006;5(2):135-42.
2006: claudio soravia; Celia D DeLozier; Zuzana Dobbie; Claudine Rey Berthod; Eviano Arrigoni; Marie-Anne Bründler; Jean-Louis Blouin; William D Foulkes; Pierre Hutter
Double frameshift mutations in APC and MSH2 in the same individual.
International journal of colorectal disease 2006;21(1):79-83.
2006: Eitan Friedman; Joanne Kotsopoulos; Jan Lubinski; Henry T Lynch; Parviz Ghadirian; Susan L Neuhausen; Claudine Isaacs; Barbara Weber; William D Foulkes; Pal Moller; Barry Rosen; Charmaine Kim-Sing; Ruth Gershoni-Baruch; Peter Ainsworth; Mary Daly; Nadine Tung; Andrea Eisen; Olufunmilayo I Olopade; Beth Y Karlan; Howard M Saal; Judy E Garber; Gad Rennert; Dawna Gilchrist; Charis Eng; Kenneth Offit; Michael Osborne; Ping Sun; Steven A Narod
Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers.
Breast cancer research : BCR 2006;8(2):R15.
2006: Kathleen K Oros; Guy Leblanc; Suzanna L Arcand; Zhen Shen; Chantal Perret; Anne-Marie Mes-Masson; William D Foulkes; Parviz Ghadirian; Diane Provencher; Patricia N Tonin
Haplotype analysis suggest common founders in carriers of the recurrent BRCA2 mutation, 3398delAAAAG, in French Canadian hereditary breast and/ovarian cancer families.
BMC medical genetics 2006;7():23.
2006: Susan McVety; Lili Li; Isabelle Thiffault; Philip H Gordon; Elizabeth MacNamara; Nora Wong; Karlene Australie; Lidia Kasprzak; George Chong; William D Foulkes
The value of multi-modal gene screening in HNPCC in Quebec: three mutations in mismatch repair genes that would have not been correctly identified by genomic DNA sequencing alone.
Familial cancer 2006;5(1):21-8.
2006: Teresa M Rudkin; Nancy Hamel; Maria Galvez; Frans B L Hogervorst; Johan J P Gille; Pål Møller; Jaran Apold; William D Foulkes
The frequent BRCA1 mutation 1135insA has multiple origins: a haplotype study in different populations.
BMC medical genetics 2006;7():15.
2006: André Nkondjock; Parviz Ghadirian; Joanne Kotsopoulos; Jan Lubinski; Henry T Lynch; Charmaine Kim-Sing; Douglas E Horsman; Barry Rosen; Claudine Isaacs; Barbara Weber; William D Foulkes; Peter Ainsworth; Nadine Tung; Andrea Eisen; Eitan Friedman; Charis Eng; Ping Sun; Steven A Narod
Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers.
International journal of cancer. Journal international du cancer 2006;118(1):103-7.
2005: Carey A Cullinane; Jan Lubinski; Susan L Neuhausen; Parviz Ghadirian; Henry T Lynch; Claudine Isaacs; Barbara Weber; Pal Moller; Kenneth Offit; Charmaine Kim-Sing; Eitan Friedman; Susan Randall; Barbara Pasini; Peter Ainsworth; Ruth Gershoni-Baruch; William D Foulkes; Jan Klijn; Nadine Tung; Gad Rennert; Olufunmilayo I Olopade; Fergus J. Couch; Teresa Wagner; Håkan Olsson; Ping Sun; Jeffrey N Weitzel; Steven A Narod
Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers.
International journal of cancer. Journal international du cancer 2005;117(6):988-91.
2005: Andrea Eisen; Jan Lubinski; Jan Klijn; Pal Moller; Henry T Lynch; Kenneth Offit; Barbara Weber; Tim Rebbeck; Susan L Neuhausen; Parviz Ghadirian; William D Foulkes; Ruth Gershoni-Baruch; Eitan Friedman; Gadi Rennert; Teresa Wagner; Claudine Isaacs; Charmaine Kim-Sing; Peter Ainsworth; Ping Sun; Steven A Narod
Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(30):7491-6.
2005: S Sun; Celia M T Greenwood; Isabelle Thiffault; Nancy Hamel; George Chong; William D Foulkes
The HNPCC associated MSH2*1906G-->C founder mutation probably originated between 1440 CE and 1715 CE in the Ashkenazi Jewish population.
Journal of medical genetics 2005;42(10):766-8.
2005: Heleen van der Klift; Juul Wijnen; Anja Wagner; Paul Verkuilen; Carli Tops; Robyn Otway; M R J Kohonen-Corish; H F A Vasen; Cristina Oliani; Daniela Barana; Pal Moller; Celia Delozier-Blanchet; Pierre Hutter; William D Foulkes; Henry T Lynch; John Burn; Gabriela Möslein; Riccardo Fodde
Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC).
Genes, chromosomes & cancer 2005;44(2):123-38.
2005: Susan McVety; Rami Younan; Lili Li; Philip H Gordon; Nora Wong; William D Foulkes; George Chong
Novel genomic insertion-- deletion in MLH1: possible mechanistic role for non-homologous end-joining DNA repair.
Clinical genetics 2005;68(3):234-8.
2005: claudio soravia; Celia D DeLozier; Zuzana Dobbie; Claudine Rey Berthod; Eviano Arrigoni; Marie-Anne Bründler; Jean-Louis Blouin; William D Foulkes; Pierre Hutter
Double frameshift mutations in APC and MSH2 in the same individual.
International journal of colorectal disease 2005;20(5):466-470.
2005: Lidia Kasprzak; Benoît Mesurolle; Francine Tremblay; Maria Galvez; Fawaz Halwani; William D Foulkes
Invasive breast cancer following bilateral subcutaneous mastectomy in a BRCA2 mutation carrier: a case report and review of the literature.
World journal of surgical oncology 2005;3():52.
2005: William D Foulkes; Nancy Hamel; Kathleen K Oros; Patricia N Tonin
BRCA mutations and ductal carcinoma in situ.
JAMA : the journal of the American Medical Association 2005;294(5):553-4.
2005: Joanne Kotsopoulos; Jan Lubinski; Henry T Lynch; Susan L Neuhausen; Parviz Ghadirian; Claudine Isaacs; Barbara Weber; Charmaine Kim-Sing; William D Foulkes; Ruth Gershoni-Baruch; Peter Ainsworth; Eitan Friedman; Mary Daly; Judy E Garber; Beth Y Karlan; Olufunmilayo I Olopade; Nadine Tung; Howard M Saal; Andrea Eisen; Michael Osborne; Håkan Olsson; Dawna Gilchrist; Ping Sun; Steven A Narod
Age at menarche and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
Cancer causes & control : CCC 2005;16(6):667-74.
2005: Jeffrey N Weitzel; Mark Robson; Barbara Pasini; Siranoush Manoukian; Dominique Stoppa-Lyonnet; Henry T Lynch; Jane McLennan; William D Foulkes; Teresa Wagner; Nadine Tung; Parviz Ghadirian; Olufunmilayo I Olopade; Claudine Isaacs; Charmaine Kim-Sing; Pal Møller; Susan L Neuhausen; Kelly A Metcalfe; Ping Sun; Steven A Narod
A comparison of bilateral breast cancers in BRCA carriers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(6):1534-8.
2005: Jarle Arnes; Jean-Sebastien Brunet; Ingunn M Stefansson; Louis R Bégin; Nora Wong; Pierre O Chappuis; Lars A Akslen; William D Foulkes
Placental cadherin and the basal epithelial phenotype of BRCA1-related breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(11):4003-11.
2005: Karin Collett; Ingunn M Stefansson; Johan Eide; Audun Braaten; Hege Wang; Geir Egil Eide; Steinar Thoresen; William D Foulkes; Lars A Akslen
A basal epithelial phenotype is more frequent in interval breast cancers compared with screen detected tumors.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(5):1108-12.
2005: I Makriyianni; Nancy Hamel; S Ward; William D Foulkes; Sharon L Graw
BRCA1:185delAG found in the San Luis Valley probably originated in a Jewish founder.
Journal of medical genetics 2005;42(5):e27.
2005: Pierre O Chappuis; E Donato; John R Goffin; Nora Wong; Louis R Bégin; Linda Kapusta; Jean-Sebastien Brunet; P Porter; William D Foulkes
Cyclin E expression in breast cancer: predicting germline BRCA1 mutations, prognosis and response to treatment.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(5):735-42.
2005: Teresa M Rudkin; William D Foulkes
BRCA2: breaks, mistakes and failed separations.
Trends in molecular medicine 2005;11(4):145-8.
2005: Kelly A Metcalfe; William D Foulkes; Henry T Lynch; Parviz Ghadirian; Nadine Tung; Ivo A Olivotto; Ellen Warner; Olufunmilayo Olopade; Andrea Eisen; Barbara Weber; Jane McLennan; Ping Sun; Steven A Narod
Effect of Prior Bilateral Oophorectomy on the Presentation of Breast Cancer in BRCA1 and BRCA2 Mutation Carriers.
Hereditary cancer in clinical practice 2005;3(2):53-7.
2005: Joanne Kotsopoulos; Olufunmilayo I Olopado; Parviz Ghadirian; Jan Lubinski; Henry T Lynch; Claudine Isaacs; Barbara Weber; Charmaine Kim-Sing; Peter Ainsworth; William D Foulkes; Andrea Eisen; Ping Sun; Steven A Narod
Changes in body weight and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
Breast cancer research : BCR 2005;7(5):R833-43.
2005: Kelly A Metcalfe; Henry T Lynch; Parviz Ghadirian; Nadine Tung; Ivo A Olivotto; William D Foulkes; Ellen Warner; Olufunmilayo I Olopade; Andrea Eisen; Barbara Weber; Jane McLennan; Ping Sun; Steven A Narod
The risk of ovarian cancer after breast cancer in BRCA1 and BRCA2 carriers.
Gynecologic oncology 2005;96(1):222-6.
2004: Kathleen K Oros; Parviz Ghadirian; Celia M T Greenwood; Chantal Perret; Zhen Shen; Yosabeth Paredes; Suzanna L Arcand; Anne-Marie Mes-Masson; Steven A Narod; William D Foulkes; Diane Provencher; Patricia N Tonin
Significant proportion of breast and/or ovarian cancer families of French Canadian descent harbor 1 of 5 BRCA1 and BRCA2 mutations.
International journal of cancer. Journal international du cancer 2004;112(3):411-9.
2004: Isabelle Thiffault; C E Schwartz; Vazken M Der Kaloustian; William D Foulkes
Mutation analysis of the tumor suppressor PTEN and the glypican 3 (GPC3) gene in patients diagnosed with Proteus syndrome.
American journal of medical genetics. Part A 2004;130A(2):123-7.
2004: Isabelle Thiffault; William D Foulkes; Victoria A Marcus; David Farber; Lidia Kasprzak; Elizabeth MacNamara; Nora Wong; Pierre Hutter; Paolo Radice; Lucio Bertario; George Chong
Putative common origin of two MLH1 mutations in Italian-Quebec hereditary non-polyposis colorectal cancer families.
Clinical genetics 2004;66(2):137-43.
2004: Helena Jernström; Jan Lubinski; Henry T Lynch; Parviz Ghadirian; Susan L Neuhausen; Claudine Isaacs; Barbara L Weber; Douglas E Horsman; Barry Rosen; William D Foulkes; Eitan Friedman; Ruth Gershoni-Baruch; Peter Ainsworth; Mary Daly; Judy E Garber; Håkan Olsson; Ping Sun; Steven A Narod
Breast-feeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
Journal of the National Cancer Institute 2004;96(14):1094-8.
2004: Ala-Eddin Al Moustafa; William D Foulkes; Annick Wong; Houda Jallal; Gerald Batist; Qunyan Yu; Meenhard Herlyn; Piotr Sicinski; Moulay A Alaoui-Jamali
Cyclin D1 is essential for neoplastic transformation induced by both E6/E7 and E6/E7/ErbB-2 cooperation in normal cells.
Oncogene 2004;23(30):5252-6.
2004: Parviz Ghadirian; Jan Lubinski; Henry T Lynch; Susan L Neuhausen; Barbara Weber; Claudine Isaacs; Ruth Gershoni Baruch; Susan Randall; Peter Ainsworth; Eitan Friedman; Eitan Freidman; Douglas E Horsman; Patricia N Tonin; William D Foulkes; Nadine Tung; Ping Sun; Steven A Narod
Smoking and the risk of breast cancer among carriers of BRCA mutations.
International journal of cancer. Journal international du cancer 2004;110(3):413-6.
2004: Kelly A Metcalfe; Henry T Lynch; Parviz Ghadirian; Nadine Tung; Ivo Olivotto; Ellen Warner; Olufunmilayo I Olopade; Andrea Eisen; Barbara Weber; Jane McLennan; Ping Sun; William D Foulkes; Steven A Narod
Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(12):2328-35.
2004: William D Foulkes; Kelly A Metcalfe; Ping Sun; Wedad M Hanna; Henry T Lynch; Parviz Ghadirian; Nadine Tung; Olufunmilayo I Olopade; Barbara L Weber; Jane McLennan; Ivo A Olivotto; Louis R Bégin; Steven A Narod
Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: the influence of age, grade, and histological type.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(6):2029-34.
2004: William D Foulkes; Jean-Sebastien Brunet; Ingunn M Stefansson; Oddbjørn Straume; Pierre O Chappuis; Louis R Bégin; Nancy Hamel; John R Goffin; Nora Wong; Michel Trudel; Linda Kapusta; Peggy Porter; Lars A Akslen
The prognostic implication of the basal-like (cyclin E high/p27 low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer.
Cancer research 2004;64(3):830-5.
2004: Isabelle Thiffault; Nancy Hamel; T Pal; Susan McVety; Victoria A Marcus; David Farber; Shannon Cowie; Jean Deschênes; Wendy S Meschino; Fabrice Odefrey; David E Goldgar; T Graham; Steven A Narod; A Kevin Watters; Elizabeth MacNamara; Desirée Du Sart; George Chong; William D Foulkes
Germline truncating mutations in both MSH2 and BRCA2 in a single kindred.
British journal of cancer 2004;90(2):483-91.
2004: Ala-Eddin Al Moustafa; William D Foulkes; Naciba Benlimame; Annick Wong; Lily Yen; Josée Bergeron; Gerald Batist; Lesley Alpert; Moulay A Alaoui-Jamali
E6/E7 proteins of HPV type 16 and ErbB-2 cooperate to induce neoplastic transformation of primary normal oral epithelial cells.
Oncogene 2004;23(2):350-8.
2004: William D Foulkes
BRCA1 functions as a breast stem cell regulator.
Journal of medical genetics 2004;41(1):1-5.
2004: Mark Robson; Pierre O Chappuis; Jaya M Satagopan; Nora Wong; Jeff Boyd; John R Goffin; Clifford Hudis; David Roberge; Larry Norton; Louis R Bégin; Kenneth Offit; William D Foulkes
A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment.
Breast cancer research : BCR 2004;6(1):R8-R17.
2003: William D Foulkes; Kelly A Metcalfe; Wedad M Hanna; Henry T Lynch; Parviz Ghadirian; Nadine Tung; Olufunmilayo I Olopade; Barbara Weber; Jane McLennan; Ivo A Olivotto; Ping Sun; Pierre O Chappuis; Louis R Bégin; Jean-Sebastien Brunet; Steven A Narod
Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma.
Cancer 2003;98(8):1569-77.
2003: William D Foulkes; Ingunn M Stefansson; Pierre O Chappuis; Louis R Bégin; John R Goffin; Nora Wong; Michel Trudel; Lars A Akslen
Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer.
Journal of the National Cancer Institute 2003;95(19):1482-5.
2003: John R Goffin; Oddbjørn Straume; Pierre O Chappuis; Jean-Sebastien Brunet; Louis R Bégin; Nancy Hamel; Nora Wong; Lars A Akslen; William D Foulkes
Glomeruloid microvascular proliferation is associated with p53 expression, germline BRCA1 mutations and an adverse outcome following breast cancer.
British journal of cancer 2003;89(6):1031-4.
2003: Nancy Hamel; Kimberley Kotar; William D Foulkes
Founder mutations in BRCA1/2 are not frequent in Canadian Ashkenazi Jewish men with prostate cancer.
BMC medical genetics 2003;4():7.
2003: Michael N Pollak; William D Foulkes
Challenges to cancer control by screening.
Nature reviews. Cancer 2003;3(4):297-303.
2003: K Kotar; Nancy Hamel; Isabelle Thiffault; William D Foulkes
The RNASEL 471delAAAG allele and prostate cancer in Ashkenazi Jewish men.
Journal of medical genetics 2003;40(3):e22.
2003: John R Goffin; Pierre O Chappuis; Louis R Bégin; Nora Wong; Jean-Sebastien Brunet; Nancy Hamel; Ann-Josée Paradis; Jeff Boyd; William D Foulkes
Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma: 10-year follow up data.
Cancer 2003;97(3):527-36.
2003: Pierre I Karakiewicz; William D Foulkes; Simon Tanguay; Mostafa Elhilali; Armen G Aprikian
Familial prostate and breast cancer in men treated with prostatectomy for prostate cancer: a population based case-control study.
The Journal of urology 2003;169(1):240-4.
2002: Oddbjørn Straume; Pierre O Chappuis; Helga B Salvesen; Ole Johan Halvorsen; Svein A Haukaas; John R Goffin; Louis R Bégin; William D Foulkes; Lars A Akslen
Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers.
Cancer research 2002;62(23):6808-11.
2002: William D Foulkes; John R Goffin; Jean-Sebastien Brunet; Louis R Bégin; Nora Wong; Pierre O Chappuis
Tamoxifen may be an effective adjuvant treatment for BRCA1-related breast cancer irrespective of estrogen receptor status.
Journal of the National Cancer Institute 2002;94(19):1504-6.
2002: Carol Cremin; Nora Wong; Karen Buzaglo; Ann-Josée Paradis; William D Foulkes
Nonovarian pelvic cancers in BRCA1/2 mutation carriers and the BRCAPRO statistical model.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(18):3936; author reply 3936-7.
2002: N Ah Mew; Nancy Hamel; Maria Galvez; M Al-Saffar; William D Foulkes
Haplotype analysis of a BRCA1: 185delAG mutation in a Chilean family supports its Ashkenazi origins.
Clinical genetics 2002;62(2):151-6.
2002: Pierre O Chappuis; John R Goffin; Nora Wong; C Perret; P Ghadirian; P N Tonin; William D Foulkes
A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancer.
Journal of medical genetics 2002;39(8):608-10.
2002: William D Foulkes; Jean-Sebastien Brunet; Nora Wong; John R Goffin; Pierre O Chappuis
Change in the penetrance of founder BRCA1/2 mutations? A retrospective cohort study.
Journal of medical genetics 2002;39(6):407-9.
2002: Khalid Laaziri; Mark Sutton; Parviz Ghadirian; A S Scott; Ann-Josée Paradis; Patricia N Tonin; William D Foulkes
Is there a correlation between the structure of hair and breast cancer or BRCA1/2 mutations?
Physics in medicine and biology 2002;47(10):1623-32.
2002: Pierre Hutter; Juul Wijnen; Claudine Rey-Berthod; Isabelle Thiffault; Paul Verkuijlen; David Farber; Nancy Hamel; B Bapat; S N Thibodeau; John Burn; J Wu; Elizabeth MacNamara; Karl Heinimann; George Chong; William D Foulkes
An MLH1 haplotype is over-represented on chromosomes carrying an HNPCC predisposing mutation in MLH1.
Journal of medical genetics 2002;39(5):323-7.
2002: Ala-Eddin Al Moustafa; Moulay A Alaoui-Jamali; Gerald Batist; Maite Hernandez-Perez; Corinne Serruya; Lesley Alpert; Martin J Black; Robert Sladek; William D Foulkes
Identification of genes associated with head and neck carcinogenesis by cDNA microarray comparison between matched primary normal epithelial and squamous carcinoma cells.
Oncogene 2002;21(17):2634-40.
2002: Anne Andermann; Isabelle Thiffault; Nora Wong; Philip Gordon; Elizabeth MacNamara; George Chong; William D Foulkes
Multimodal molecular screening is required to improve the sensitivity of MLH1 and MSH2 mutation analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(6):1705-7.
2002: Parviz Ghadirian; Geoffrey Liu; Steven Gallinger; Beverly Schmocker; Ann-Josée Paradis; Geeta Lal; Jean-Sebastien Brunet; William D Foulkes; Steven A Narod
Risk of pancreatic cancer among individuals with a family history of cancer of the pancreas.
International journal of cancer. Journal international du cancer 2002;97(6):807-10.
2002: William D Foulkes
Of mice and women.
Cancer cell 2002;1(1):11-2.
2002: Ziqiang Yuan; Bruce Gottlieb; Lenore K Beitel; Nora Wong; Philip H Gordon; Qing Wang; Alain Puisieux; William D Foulkes; Mark Trifiro
Polymorphisms and HNPCC: PMS2-MLH1 protein interactions diminished by single nucleotide polymorphisms.
Human mutation 2002;19(2):108-13.
2002: Marie-Noël Hébert-Blouin; Vayia Koufogianis; Peter Gillett; William D Foulkes
Fallopian tube cancer in a BRCA1 mutation carrier: rapid development and failure of screening.
American journal of obstetrics and gynecology 2002;186(1):53-4.
2002: Pierre O Chappuis; William D Foulkes
Risk assessment & genetic testing.
Cancer treatment and research 2002;107():29-59.
2001: John R Goffin; Pierre O Chappuis; Nora Wong; William D Foulkes
Re: Magnetic resonance imaging and mammography in women with a hereditary risk of breast cancer.
Journal of the National Cancer Institute 2001;93(22):1754-5.
2001: William D Foulkes; Joseph D Rosenblatt; Pierre O Chappuis
The contribution of inherited factors to the clinicopathological features and behavior of breast cancer.
Journal of mammary gland biology and neoplasia 2001;6(4):453-65.
2001: Ingo B Runnebaum; Shan Wang-Gohrke; Danny Vesprini; Rolf Kreienberg; Henry T Lynch; Roxana Moslehi; Parviz Ghadirian; Barbara Weber; Andrew K Godwin; Harvey A Risch; Judy E Garber; C Lerman; Olufunmilayo I Olopade; William D Foulkes; Beth Y Karlan; Ellen Warner; Barry Rosen; Timothy R Rebbeck; P Tonin; M P Dubé; Dirk G Kieback; Steven A Narod
Progesterone receptor variant increases ovarian cancer risk in BRCA1 and BRCA2 mutation carriers who were never exposed to oral contraceptives.
Pharmacogenetics 2001;11(7):635-8.
2001: Pierre O Chappuis; Nancy Hamel; Ann-Josée Paradis; Jean Deschênes; André Robidoux; C Potvin; J Cantin; Patricia N Tonin; Parviz Ghadirian; William D Foulkes
Prevalence of founder BRCA1 and BRCA2 mutations in unselected French Canadian women with breast cancer.
Clinical genetics 2001;59(6):418-23.
2001: Patricia N Tonin; C Perret; J A Lambert; Ann-Josée Paradis; T Kantemiroff; M H Benoît; G Martin; William D Foulkes; Parviz Ghadirian
Founder BRCA1 and BRCA2 mutations in early-onset French Canadian breast cancer cases unselected for family history.
International journal of cancer. Journal international du cancer 2001;95(3):189-93.
2001: Marc S Greenblatt; Pierre O Chappuis; Jeffrey P Bond; Nancy Hamel; William D Foulkes
TP53 mutations in breast cancer associated with BRCA1 or BRCA2 germ-line mutations: distinctive spectrum and structural distribution.
Cancer research 2001;61(10):4092-7.
2001: R Rabelo; William D Foulkes; Philip H Gordon; Nora Wong; Ziqiang Yuan; Elizabeth MacNamara; George Chong; Leonard Pinsky; Dana Lasko
Role of molecular diagnostic testing in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer families.
Diseases of the colon and rectum 2001;44(3):437-46.
2001: Nora Wong; Dana Lasko; R Rabelo; Leonard Pinsky; Philip H Gordon; William D Foulkes
Genetic counseling and interpretation of genetic tests in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer.
Diseases of the colon and rectum 2001;44(2):271-9.
2001: Pierre O Chappuis; Nancy Hamel; Ann-Josée Paradis; Jean Deschênes; Patricia N Tonin; Parviz Ghadirian; William D Foulkes
Re: Population-based study of BRCA1 and BRCA2 mutations in 1035 unselected Finnish breast cancer patients.
Journal of the National Cancer Institute 2001;93(2):152-4.
2001: T Pal; Nancy Hamel; Danny Vesprini; K Sanders; M Mitchell; Nada Quercia; N Ng Cheong; A Murray; William D Foulkes; Steven A Narod
Double primary cancers of the breast and thyroid in women: molecular analysis and genetic implications.
Familial cancer 2001;1(1):17-24.
2001: A P Manning; D Abelovich; Parviz Ghadirian; J A Lambert; Danielle Frappier; Diane Provencher; André Robidoux; T Peretz; Steven A Narod; Anne-Marie Mes-Masson; William D Foulkes; T Wang; Kenneth Morgan; T Mary Fujiwara; Patricia N Tonin
Haplotype analysis of BRCA2 8765delAG mutation carriers in French Canadian and Yemenite Jewish hereditary breast cancer families.
Human heredity 2001;52(2):116-20.
2000: Pierre O Chappuis; Linda Kapusta; Louis R Bégin; Nora Wong; Jean-Sebastien Brunet; Steven A Narod; Joyce M Slingerland; William D Foulkes
Germline BRCA1/2 mutations and p27(Kip1) protein levels independently predict outcome after breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(24):4045-52.
2000: Kelly A Metcalfe; Alexander Liede; E Hoodfar; A Scott; William D Foulkes; Steven A Narod
An evaluation of needs of female BRCA1 and BRCA2 carriers undergoing genetic counselling.
Journal of medical genetics 2000;37(11):866-74.
2000: Nancy Hamel; S Karimi; M N Hébert-Blouin; Jean-Sebastien Brunet; B Gilfix; Parviz Ghadirian; M J Black; steven narod; William D Foulkes
Increased risk of head and neck cancer in association with GSTT1 nullizygosity for individuals with low exposure to tobacco.
International journal of cancer. Journal international du cancer 2000;87(3):452-4.
2000: Pierre O Chappuis; V Nethercot; William D Foulkes
Clinico-pathological characteristics of BRCA1- and BRCA2-related breast cancer.
Seminars in surgical oncology 2000;18(4):287-95.
2000: Geoffrey Liu; Parviz Ghadirian; Danny Vesprini; Nancy Hamel; Ann-Josée Paradis; Geeta Lal; Steven Gallinger; Steven A Narod; William D Foulkes
Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma.
British journal of cancer 2000;82(10):1646-9.
2000: William D Foulkes; Pierre O Chappuis; Nora Wong; Jean-Sebastien Brunet; Danny Vesprini; F Rozen; Ziqiang Yuan; MN Pollak; G Kuperstein; Steven A Narod; Louis R Bégin
Primary node negative breast cancer in BRCA1 mutation carriers has a poor outcome.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(3):307-13.
2000: Graciela Kuperstein; William D Foulkes; Parviz Ghadirian; J Hakimi; Steven A Narod
A rapid fluorescent multiplexed-PCR analysis (FMPA) for founder mutations in the BRCA1 and BRCA2 genes.
Clinical genetics 2000;57(3):213-20.
2000: Nancy Hamel; M J Black; Parviz Ghadirian; William D Foulkes
No association between P53 codon 72 polymorphism and risk of squamous cell carcinoma of the head and neck.
British journal of cancer 2000;82(4):757-9.
1999: Nancy Hamel; A Manning; M J Black; Patricia N Tonin; William D Foulkes
An absence of founder BRCA2 mutations in individuals with squamous cell carcinoma of the head and neck.
International journal of cancer. Journal international du cancer 1999;83(6):803-4.
1999: William D Foulkes; Jean-Sebastien Brunet; Ellen Warner; P J Goodwin; Wendy S Meschino; Steven A Narod; P E Goss; Gord Glendon
The importance of a family history of breast cancer in predicting the presence of a BRCA mutation.
American journal of human genetics 1999;65(6):1776-9.
1999: Helena Jernström; C Lerman; Parviz Ghadirian; Henry T Lynch; Barbara Weber; Judy E Garber; Mary Daly; Olufunmilayo I Olopade; William D Foulkes; Ellen Warner; Jean-Sebastien Brunet; Steven A Narod
Pregnancy and risk of early breast cancer in carriers of BRCA1 and BRCA2.
Lancet 1999;354(9193):1846-50.
1999: Ziqiang Yuan; Louis R Bégin; Nora Wong; Jean-Sebastien Brunet; Mark Trifiro; Philip H Gordon; Leonard Pinsky; William D Foulkes
The effect of the I1307K APC polymorphism on the clinicopathological features and natural history of breast cancer.
British journal of cancer 1999;81(5):850-4.
1999: Pierre O Chappuis; Joseph D Rosenblatt; William D Foulkes
The influence of familial and hereditary factors on the prognosis of breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(10):1163-70.
1999: Ziqiang Yuan; Nora Wong; William D Foulkes; L Alpert; F Manganaro; Corinne Andreutti-Zaugg; Richard D Iggo; K Anthony; ET Hsieh; Mark Redston; Leonard Pinsky; Mark Trifiro; Philip H Gordon; Dana Lasko
A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screening.
Journal of medical genetics 1999;36(10):790-3.
1999: P O Chappuis; steven narod; William D Foulkes
Screening for ovarian cancer.
Lancet 1999;354(9177):509-10.
1999: Ellen Warner; William D Foulkes; P Goodwin; Wendy S Meschino; John Blondal; C Paterson; Hilmi Ozcelik; P Goss; D Allingham-Hawkins; Nancy Hamel; LS Di Prospero; V Contiga; C Serruya; M Klein; Roxana Moslehi; J Honeyford; Alexander Liede; Gord Glendon; Jean-Sebastien Brunet; Steven A Narod
Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancer.
Journal of the National Cancer Institute 1999;91(14):1241-7.
1999: Lidia Kasprzak; William D Foulkes; A N Shelling
Forth nightly review: hereditary ovarian carcinoma.
BMJ (Clinical research ed.) 1999;318(7186):786-9.
1998: T Pal; T Flanders; M Mitchell-Lehman; A MacMillan; Jean-Sebastien Brunet; Steven A Narod; William D Foulkes
Genetic implications of double primary cancers of the colorectum and endometrium.
Journal of medical genetics 1998;35(12):978-84.
1998: Patricia N Tonin; Anne-Marie Mes-Masson; P A Futreal; Kenneth Morgan; M Mahon; William D Foulkes; David E C Cole; Diane Provencher; Parviz Ghadirian; Steven A Narod
Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families.
American journal of human genetics 1998;63(5):1341-51.
1998: William D Foulkes
BRCA1 and BRCA2: penetrating the clinical arena.
Lancet 1998;352(9137):1325-6.
1998: Ziqiang Yuan; Lidia Kasprzak; Philip H Gordon; Leonard Pinsky; William D Foulkes
I1307K APC and hMLH1 mutations in a non-Jewish family with hereditary non-polyposis colorectal cancer.
Clinical genetics 1998;54(4):368-70.
1998: William D Foulkes; Nora Wong; Jean-Sebastien Brunet; Steven A Narod
BRCA mutations and survival in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(9):3206-8.
1998: Mark Redston; Katherine L Nathanson; Ziqiang Yuan; Susan L Neuhausen; Jaya M Satagopan; Nora Wong; D Yang; D Nafa; JL Abrahamson; Hilmi Ozcelik; Danielle Antin-Ozerkis; Irene L Andrulis; M Daly; Leonard Pinsky; Deborah Schrag; S Gallinger; M Kaback; Mary-Claire King; T Woodage; Lawrence C Brody; A Godwin; Ellen Warner; Barbara Weber; William D Foulkes; Kenneth Offit
The APCI1307K allele and breast cancer risk.
Nature genetics 1998;20(1):13-4.
1998: B Godard; William D Foulkes; Diane Provencher; Jean-Sebastien Brunet; P N Tonin; Anne-Marie Mes-Masson; Steven A Narod; Parviz Ghadirian
Risk factors for familial and sporadic ovarian cancer among French Canadians: a case-control study.
American journal of obstetrics and gynecology 1998;179(2):403-10.
1998: Jean-Sebastien Brunet; Parviz Ghadirian; Timothy R Rebbeck; C Lerman; Judy E Garber; P N Tonin; JL Abrahamson; William D Foulkes; Mary Daly; J Wagner-Costalas; A Godwin; Olufunmilayo I Olopade; Roxana Moslehi; Alexander Liede; P A Futreal; B L Weber; G M Lenoir; Henry T Lynch; Steven A Narod
Effect of smoking on breast cancer in carriers of mutant BRCA1 or BRCA2 genes.
Journal of the National Cancer Institute 1998;90(10):761-6.
1998: William D Foulkes; Nora Wong; F Rozen; Jean-Sebastien Brunet; Steven A Narod
Survival of patients with breast cancer and BRCA1 mutations.
Lancet 1998;351(9112):1359-60.
1998: Alexander Liede; P N Tonin; C C Sun; C Serruya; M B Daly; Steven A Narod; William D Foulkes
Is hereditary site-specific ovarian cancer a distinct genetic condition?
American journal of medical genetics 1998;75(1):55-8.
1998: Pam Pollock; N Spurr; D Timothy Bishop; J Newton-Bishop; Nelleke A Gruis; Pieter A van der Velden; A M Goldstein; M A Tucker; William D Foulkes; R Barnhill; D Haber; JW Fountain; Nicholas K Hayward
Haplotype analysis of two recurrent CDKN2A mutations in 10 melanoma families: evidence for common founders and independent mutations.
Human mutation 1998;11(6):424-31.
1997: William D Foulkes; Nora Wong; Jean-Sebastien Brunet; Louis R Bégin; J C Zhang; J J Martinez; F Rozen; Patricia N Tonin; Steven A Narod; S E Karp; MN Pollak
Germ-line BRCA1 mutation is an adverse prognostic factor in Ashkenazi Jewish women with breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(12 Pt 1):2465-9.
1997: S Sun; Pam Pollock; L Liu; S Karimi; Serge Jothy; B J Milner; A Renwick; Norman Lassam; Nicholas K Hayward; David Hogg; Steven A Narod; William D Foulkes
CDKN2A mutation in a non-FAMMM kindred with cancers at multiple sites results in a functionally abnormal protein.
International journal of cancer. Journal international du cancer 1997;73(4):531-6.
1997: Harriet Druker; Lidia Kasprzak; L R Bégin; Serge Jothy; Steven A Narod; William D Foulkes
Family with Graves disease, multinodular goiter, nonmedullary thyroid carcinoma, and alveolar rhabdomyosarcoma.
American journal of medical genetics 1997;72(1):30-3.
1997: William D Foulkes; P N Buu; D Filiatrault; J M Leclerc; steven narod
Excess of congenital abnormalities in French-Canadian children with neuroblastoma: a case series study from Montréal.
Medical and pediatric oncology 1997;29(4):272-9.
1997: S E Karp; Patricia N Tonin; Louis R Bégin; J J Martinez; J C Zhang; MN Pollak; William D Foulkes
Influence of BRCA1 mutations on nuclear grade and estrogen receptor status of breast carcinoma in Ashkenazi Jewish women.
Cancer 1997;80(3):435-41.
1997: Jean-Sebastien Brunet; Steven A Narod; Patricia N Tonin; William D Foulkes
BRCA1 mutations and survival in women with ovarian cancer.
The New England journal of medicine 1997;336(17):1256; author reply 1256-7.
1997: William D Foulkes; T Y Flanders; Pam Pollock; Nicholas K Hayward
The CDKN2A (p16) gene and human cancer.
Molecular medicine (Cambridge, Mass.) 1997;3(1):5-20.
1996: Corey Cutler; William D Foulkes; Jean-Sebastien Brunet; T Y Flanders; H Shibata; Steven A Narod
Cutaneous malignant melanoma in women is uncommonly associated with a family history of melanoma in first-degree relatives: a case-control study.
Melanoma research 1996;6(6):435-40.
1996: T Y Flanders; William D Foulkes
Pancreatic adenocarcinoma: epidemiology and genetics.
Journal of medical genetics 1996;33(11):889-98.
1996: Patricia N Tonin; Barbara Weber; Kenneth Offit; Fergus J. Couch; Timothy R Rebbeck; Susan L Neuhausen; A K Godwin; Mary Daly; J Wagner-Costalos; D Berman; G Grana; E Fox; Michael F Kane; R D Kolodner; michael krainer; Daniel A Haber; Jeffery Struewing; Ellen Warner; B Rosen; Caryn Lerman; Beth N Peshkin; Larry Norton; OM Serova; William D Foulkes; Judy E Garber
Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families.
Nature medicine 1996;2(11):1179-83.
1996: William D Foulkes; Jean-Sebastien Brunet; W Sieh; Martin J Black; George Shenouda; Steven A Narod
Familial risks of squamous cell carcinoma of the head and neck: retrospective case-control study.
BMJ (Clinical research ed.) 1996;313(7059):716-21.
1996: William D Foulkes; N Bolduc; D Lambert; O Ginsburg; L Olien; D W Yandell; Patricia N Tonin; Steven A Narod
Increased incidence of cancer in first degree relatives of women with double primary carcinomas of the breast and colon.
Journal of medical genetics 1996;33(7):534-9.
1996: CM Phelan; Johnathan M Lancaster; Patricia N Tonin; Curtis Gumbs; C Cochran; R Carter; Parviz Ghadirian; C Perret; Roxana Moslehi; F Dion; M C Faucher; K Dole; S Karimi; William D Foulkes; H Lounis; Ellen Warner; P Goss; D Anderson; Catharina Larsson; Steven A Narod; P Andrew Futreal
Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families.
Nature genetics 1996;13(1):120-2.
1996: William D Foulkes; Steven A Narod
Screening for cancer in high-risk families.
Cancer treatment and research 1996;86():165-82.
1995: William D Foulkes; Jean-Sebastien Brunet; Luiz Paulo Kowalski; Steven A Narod; Eduardo L Franco
Family history of cancer is a risk factor for squamous cell carcinoma of the head and neck in Brazil: a case-control study.
International journal of cancer. Journal international du cancer 1995;63(6):769-73.
1995: William D Foulkes
A tale of four syndromes: familial adenomatous polyposis, Gardner syndrome, attenuated APC and Turcot syndrome.
QJM : monthly journal of the Association of Physicians 1995;88(12):853-63.
1995: William D Foulkes; Gordon Stamp; S Afzal; N Lalani; C P McFarlane; J Trowsdale; I G Campbell
MDM2 overexpression is rare in ovarian carcinoma irrespective of TP53 mutation status.
British journal of cancer 1995;72(4):883-8.
1995: William D Foulkes; Gord Glendon; Steven A Narod
Family history and risk of ovarian cancer.
JAMA : the journal of the American Medical Association 1995;274(5):383.