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William Foulkes

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

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Ghadirian P; Robidoux A; Zhang P; Royer R; Akbari M; Zhang S; Fafard E; Costa M; Martin G; Potvin C; Patocskai E; Larouche N; Younan R; Nassif E; Giroux S; Narod S A; Rousseau F; Foulkes W D
The contribution of founder mutations to early-onset breast cancer in French-Canadian women.
Li Lili; Biswas Kajal; Habib Laura Anne; Kuznetsov Sergey G; Hamel Nancy; Kirchhoff Tomas; Wong Nora; Armel Susan; Chong George; Narod Steven A; Claes Kathleen; Offit Kenneth; Robson Mark E; Stauffer Stacey; Sharan Shyam K; Foulkes William D
Functional redundancy of exon 12 of BRCA2 revealed by a comprehensive analysis of the c.6853A>G (p.I2285V) variant.
Tischkowitz Marc D; Sabbaghian Nelly; Hamel Nancy; Borgida Ayelet; Rosner Chaim; Taherian Nassim; Srivastava Archana; Holter Spring; Rothenmund Heidi; Ghadirian Parviz; Foulkes William D; Gallinger Steven
Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer.

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All Publications

2009: Ghadirian P; Robidoux A; Zhang P; Royer R; Akbari M; Zhang S; Fafard E; Costa M; Martin G; Potvin C; Patocskai E; Larouche N; Younan R; Nassif E; Giroux S; Narod S A; Rousseau F; Foulkes W D
The contribution of founder mutations to early-onset breast cancer in French-Canadian women.
Clinical genetics 2009;76(5):421-6.
2009: Li Lili; Biswas Kajal; Habib Laura Anne; Kuznetsov Sergey G; Hamel Nancy; Kirchhoff Tomas; Wong Nora; Armel Susan; Chong George; Narod Steven A; Claes Kathleen; Offit Kenneth; Robson Mark E; Stauffer Stacey; Sharan Shyam K; Foulkes William D
Functional redundancy of exon 12 of BRCA2 revealed by a comprehensive analysis of the c.6853A>G (p.I2285V) variant.
Human mutation 2009;30(11):1543-50.
2009: Tischkowitz Marc D; Sabbaghian Nelly; Hamel Nancy; Borgida Ayelet; Rosner Chaim; Taherian Nassim; Srivastava Archana; Holter Spring; Rothenmund Heidi; Ghadirian Parviz; Foulkes William D; Gallinger Steven
Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer.
Gastroenterology 2009;137(3):1183-6.
2009: Novak David J; Sabbaghian Nelly; Maillet Philippe; Chappuis Pierre O; Foulkes William D; Tischkowitz Marc
Analysis of the genes coding for the BRCA1-interacting proteins, RAP80 and Abraxas (CCDC98), in high-risk, non-BRCA1/2, multiethnic breast cancer cases.
Breast cancer research and treatment 2009;117(2):453-9.
2009: Foulkes William D; Grainge Matthew J; Rakha Emad A; Green Andrew R; Ellis Ian O
Tumor size is an unreliable predictor of prognosis in basal-like breast cancers and does not correlate closely with lymph node status.
Breast cancer research and treatment 2009;117(1):199-204.
2009: Huang Fleur; Kushner Yael B; Langleben Adrian; Foulkes William D;
Eleven years disease-free: role of chemotherapy in metastatic BRCA2-related breast cancer.
Nature reviews. Clinical oncology 2009;6(8):488-92.
2009: Arnes J B; Bégin L R; Stefansson I; Brunet J-S; Nielsen T O; Foulkes W D; Akslen L A
Expression of epidermal growth factor receptor in relation to BRCA1 status, basal-like markers and prognosis in breast cancer.
Journal of clinical pathology 2009;62(2):139-46.
2009: Baker Kristi; Foulkes William D; Jass Jeremy R
MSI-H colorectal cancers preferentially retain and expand intraepithelial lymphocytes rather than peripherally derived CD8+ T cells.
Cancer immunology, immunotherapy : CII 2009;58(1):135-44.
2008: Palma Laura; Marcus Victoria; Gilbert Lucy; Chong George; Foulkes William D
Synchronous occult cancers of the endometrium and fallopian tube in an MSH2 mutation carrier at time of prophylactic surgery.
Gynecologic oncology 2008;111(3):575-8.
2008: Kotsopoulos Joanne; Librach Clifford L; Lubinski Jan; Gronwald Jacek; Kim-Sing Charmaine; Ghadirian Parviz; Lynch Henry T; Moller Pal; Foulkes William D; Randall Susan; Manoukian Siranoush; Pasini Barbara; Tung Nadine; Ainsworth Peter J; Cummings Shelly; Sun Ping; Narod Steven A;
Infertility, treatment of infertility, and the risk of breast cancer among women with BRCA1 and BRCA2 mutations: a case-control study.
Cancer causes & control : CCC 2008;19(10):1111-9.
2008: Foulkes William D
Inherited susceptibility to common cancers.
The New England journal of medicine 2008;359(20):2143-53.
2008: Greenblatt Marc S; Brody Lawrence C; Foulkes William D; Genuardi Maurizio; Hofstra Robert M W; Olivier Magali; Plon Sharon E; Sijmons Rolf H; Sinilnikova Olga; Spurdle Amanda B;
Locus-specific databases and recommendations to strengthen their contribution to the classification of variants in cancer susceptibility genes.
Human mutation 2008;29(11):1273-81.
2008: Tischkowitz Marc D; Yilmaz Ahmet; Chen Long Q; Karyadi Danielle M; Novak David; Kirchhoff Tomas; Hamel Nancy; Tavtigian Sean V; Kolb Suzanne; Bismar Tarek A; Aloyz Raquel; Nelson Peter S; Hood Lee; Narod Steven A; White Kirsten A; Ostrander Elaine A; Isaacs William B; Offit Kenneth; Cooney Kathleen A; Stanford Janet L; Foulkes William D
Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer.
Cancer letters 2008;270(1):173-80.
2008: Campeau Philippe M; Foulkes William D; Tischkowitz Marc D
Hereditary breast cancer: new genetic developments, new therapeutic avenues.
Human genetics 2008;124(1):31-42.
2008: Narod S A; Neuhausen S; Vichodez G; Armel S; Lynch H T; Ghadirian P; Cummings S; Olopade O; Stoppa-Lyonnet D; Couch F; Wagner T; Warner E; Foulkes W D; Saal H; Weitzel J; Tulman A; Poll A; Nam R; Sun P; Danquah Jessica; Domchek Susan; Tung Nadine; Ainsworth Peter; Horsman Douglas; Kim-Sing Charmaine; Maugard Christine; Eisen Andrea; Daly Mary; McKinnon Wendy; Wood Marie; Isaacs Claudine; Gilchrist Dawna; Karlan Beth; Nedelcu Raluca; Meschino Wendy; Garber Judy; Pasini Barbara; Manoukian Siranoush; Bellati Christina
Rapid progression of prostate cancer in men with a BRCA2 mutation.
British journal of cancer 2008;99(2):371-4.
2008: Tischkowitz Marc; Hamel Nancy; Carvalho Marcelo A; Birrane Gabriel; Soni Aditi; van Beers Erik H; Joosse Simon A; Wong Nora; Novak David; Quenneville Louise A; Grist Scott A; Nederlof Petra M; Goldgar David E; Tavtigian Sean V; Monteiro Alvaro N; Ladias John A A; Foulkes William D
Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
European journal of human genetics : EJHG 2008;16(7):820-32.
2008: Metcalfe K A; Foulkes W D; Kim-Sing C; Ainsworth P; Rosen B; Armel S; Poll A; Eisen A; Gilchrist D; Chudley A; Ghadirian P; Maugard C; Lemire E G; Sun P; Narod S A
Family history as a predictor of uptake of cancer preventive procedures by women with a BRCA1 or BRCA2 mutation.
Clinical genetics 2008;73(5):474-9.
2008: Tischkowitz Marc; Sabbaghian Nelly; Ray Anna M; Lange Ethan M; Foulkes William D; Cooney Kathleen A
Analysis of the gene coding for the BRCA2-interacting protein PALB2 in hereditary prostate cancer.
The Prostate 2008;68(6):675-8.
2008: Metcalfe Kelly A; Birenbaum-Carmeli Daphna; Lubinski Jan; Gronwald Jacek; Lynch Henry; Moller Pal; Ghadirian Parviz; Foulkes William D; Klijn Jan; Friedman Eitan; Kim-Sing Charmaine; Ainsworth Peter; Rosen Barry; Domchek Susan; Wagner Teresa; Tung Nadine; Manoukian Siranoush; Couch Fergus; Sun Ping; Narod Steven A;
International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers.
International journal of cancer. Journal international du cancer 2008;122(9):2017-22.
2008: Arcand Suzanna L; Maugard Christine M; Ghadirian Parviz; Robidoux André; Perret Chantal; Zhang Phil; Fafard Eve; Mes-Masson Anne-Marie; Foulkes William D; Provencher Diane; Narod Steven A; Tonin Patricia N
Germline TP53 mutations in BRCA1 and BRCA2 mutation-negative French Canadian breast cancer families.
Breast cancer research and treatment 2008;108(3):399-408.
2008: Metcalfe Kelly A; Lubinski Jan; Ghadirian Parviz; Lynch Henry; Kim-Sing Charmaine; Friedman Eitan; Foulkes William D; Domchek Susan; Ainsworth Peter; Isaacs Claudine; Tung Nadine; Gronwald Jacek; Cummings Shelly; Wagner Teresa; Manoukian Siranoush; Møller Pål; Weitzel Jeffrey; Sun Ping; Narod Steven A;
Predictors of contralateral prophylactic mastectomy in women with a BRCA1 or BRCA2 mutation: the Hereditary Breast Cancer Clinical Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(7):1093-7.
2008: Vu Thien-Tuong-Vi; Zeitouni Anthony G; Tsinalis Pantelis; Foulkes William D; Hagr Abdulrahman
Familial clustering of parotid gland lymphoepithelioma in North America.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 2008;37(1):23-6.
2008: Foulkes William D
BRCA1--sowing the seeds crooked in the furrow.
Nature genetics 2008;40(1):8-9.
2008: Novak David J; Chen Long Qi; Ghadirian Parviz; Hamel Nancy; Zhang Phil; Rossiny Vanessa; Cardinal Guy; Robidoux André; Tonin Patricia N; Rousseau Francois; Narod Steven A; Foulkes William D
Identification of a novel CHEK2 variant and assessment of its contribution to the risk of breast cancer in French Canadian women.
BMC cancer 2008;8():239.
2007: Foulkes William D
p53--master and commander.
The New England journal of medicine 2007;357(25):2539-41.
2007: Foulkes William D
Clinically relevant biology of hereditary breast cancer.
Seminars in oncology 2007;34(5):379-83.
2007: Yasmeen Amber; Bismar Tarek A; Kandouz Mustapha; Foulkes William D; Desprez Pierre-Yves; Al Moustafa Ala-Eddin
E6/E7 of HPV type 16 promotes cell invasion and metastasis of human breast cancer cells.
Cell cycle (Georgetown, Tex.) 2007;6(16):2038-42.
2007: Apicella C; Dowty J G; Dite G S; Jenkins M A; Senie R T; Daly M B; Andrulis I L; John E M; Buys S S; Li F P; Glendon G; Chung W; Ozcelik H; Miron A; Kotar K; Southey M C; Foulkes W D; Hopper J L
Validation study of the LAMBDA model for predicting the BRCA1 or BRCA2 mutation carrier status of North American Ashkenazi Jewish women.
Clinical genetics 2007;72(2):87-97.
2007: Mesurolle Benoît; Kadoch Laurence; El-Khoury Mona; Lisbona André; Dendukuri Nandini; Foulkes William D
Sonographic features of breast carcinoma presenting as masses in BRCA gene mutation carriers.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2007;26(6):817-24.
2007: Tischkowitz Marc; Xia Bing; Sabbaghian Nelly; Reis-Filho Jorge S; Hamel Nancy; Li Guilan; van Beers Erik H; Li Lili; Khalil Tayma; Quenneville Louise A; Omeroglu Atilla; Poll Aletta; Lepage Pierre; Wong Nora; Nederlof Petra M; Ashworth Alan; Tonin Patricia N; Narod Steven A; Livingston David M; Foulkes William D
Analysis of PALB2/FANCN-associated breast cancer families.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(16):6788-93.
2007: Hamel Nancy; Wong Nora; Alpert Lesley; Galvez Maria; Foulkes William D
Mixed ovarian germ cell tumor in a BRCA2 mutation carrier.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2007;26(2):160-4.
2007: Refae Munir Al; Wong Nora; Patenaude François; Bégin Louis R; Foulkes William D
Hereditary leiomyomatosis and renal cell cancer: an unusual and aggressive form of hereditary renal carcinoma.
Nature clinical practice. Oncology 2007;4(4):256-61.
2007: McLaughlin John R; Risch Harvey A; Lubinski Jan; Moller Pal; Ghadirian Parviz; Lynch Henry; Karlan Beth; Fishman David; Rosen Barry; Neuhausen Susan L; Offit Kenneth; Kauff Noah; Domchek Susan; Tung Nadine; Friedman Eitan; Foulkes William; Sun Ping; Narod Steven A;
Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study.
The lancet oncology 2007;8(1):26-34.
2007: Foulkes William D; Ghadirian Parviz; Akbari Mohammed Reza; Hamel Nancy; Giroux Sylvie; Sabbaghian Nelly; Darnel Andrew; Royer Robert; Poll Aletta; Fafard Eve; Robidoux André; Martin Ginette; Bismar Tarek A; Tischkowitz Marc; Rousseau Francois; Narod Steven A
Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women.
Breast cancer research : BCR 2007;9(6):R83.
2007: Tischkowitz Marc; Brunet Jean-Sébastien; Bégin Louis R; Huntsman David G; Cheang Maggie C U; Akslen Lars A; Nielsen Torsten O; Foulkes William D
Use of immunohistochemical markers can refine prognosis in triple negative breast cancer.
BMC cancer 2007;7():134.
2006: Baker K; Chong G; Foulkes W D; Jass J R
Transforming growth factor-beta pathway disruption and infiltration of colorectal cancers by intraepithelial lymphocytes.
Histopathology 2006;49(4):371-80.
2006: Oros K K; Ghadirian P; Maugard C M; Perret C; Paredes Y; Mes-Masson A-M; Foulkes W D; Provencher D; Tonin P N
Application of BRCA1 and BRCA2 mutation carrier prediction models in breast and/or ovarian cancer families of French Canadian descent.
Clinical genetics 2006;70(4):320-9.
2006: Shinto Eiji; Baker Kristi; Tsuda Hitoshi; Mochizuki Hidetaka; Ueno Hideki; Matsubara Osamu; Foulkes William D; Jass Jeremy R
Tumor buds show reduced expression of laminin-5 gamma 2 chain in DNA mismatch repair deficient colorectal cancer.
Diseases of the colon and rectum 2006;49(8):1193-202.
2006: Finch Amy; Beiner Mario; Lubinski Jan; Lynch Henry T; Moller Pal; Rosen Barry; Murphy Joan; Ghadirian Parviz; Friedman Eitan; Foulkes William D; Kim-Sing Charmaine; Wagner Teresa; Tung Nadine; Couch Fergus; Stoppa-Lyonnet Dominique; Ainsworth Peter; Daly Mary; Pasini Babara; Gershoni-Baruch Ruth; Eng Charis; Olopade Olufunmilayo I; McLennan Jane; Karlan Beth; Weitzel Jeffrey; Sun Ping; Narod Steven A;
Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation.
JAMA : the journal of the American Medical Association 2006;296(2):185-92.
2006: Galiatsatos P; Kasprzak L; Chong G; Jass J R; Foulkes W D
Multiple primary malignancies in a patient with situs ambiguus.
Clinical genetics 2006;69(6):528-31.
2006: Tischkowitz Marc D; Foulkes William D
The basal phenotype of BRCA1-related breast cancer: past, present and future.
Cell cycle (Georgetown, Tex.) 2006;5(9):963-7.
2006: Goswami Rashmi S; Minoo Parham; Baker Kristi; Chong George; Foulkes William D; Jass Jeremy R
Hyperplastic polyposis and cancer of the colon with gastrinoma of the duodenum.
Nature clinical practice. Oncology 2006;3(5):281-4; quiz 285.
2006: Narod Steven A; Lubinski Jan; Ghadirian Parviz; Lynch Henry T; Moller Pal; Foulkes William D; Rosen Barry; Kim-Sing Charmaine; Isaacs Claudine; Domchek Susan; Sun Ping;
Screening mammography and risk of breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study.
The lancet oncology 2006;7(5):402-6.
2006: Gronwald Jacek; Tung Nadine; Foulkes William D; Offit Kenneth; Gershoni Ruth; Daly Mary; Kim-Sing Charmaine; Olsson Hakan; Ainsworth Peter; Eisen Andrea; Saal Howard; Friedman Eitan; Olopade Olufunmilayo; Osborne Michael; Weitzel Jeffrey; Lynch Henry; Ghadirian Parviz; Lubinski Jan; Sun Ping; Narod Steven A;
Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: an update.
International journal of cancer. Journal international du cancer 2006;118(9):2281-4.
2006: Li Lili; McVety Susan; Younan Rami; Liang Ping; Du Sart Desirée; Gordon Philip H; Hutter Pierre; Hogervorst Frans B L; Chong George; Foulkes William D
Distinct patterns of germ-line deletions in MLH1 and MSH2: the implication of Alu repetitive element in the genetic etiology of Lynch syndrome (HNPCC).
Human mutation 2006;27(4):388.
2006: Galiatsatos Polymnia; Foulkes William D
Familial adenomatous polyposis.
The American journal of gastroenterology 2006;101(2):385-98.
2006: McVety S; Li L; Gordon P H; Chong G; Foulkes W D
Disruption of an exon splicing enhancer in exon 3 of MLH1 is the cause of HNPCC in a Quebec family.
Journal of medical genetics 2006;43(2):153-6.
2006: Soravia Claudio; DeLozier Celia D; Dobbie Zuzana; Berthod Claudine Rey; Arrigoni Eviano; Bründler Marie-Anne; Blouin Jean-Louis; Foulkes William D; Hutter Pierre
Double frameshift mutations in APC and MSH2 in the same individual.
International journal of colorectal disease 2006;21(1):79-83.
2006: Nkondjock André; Ghadirian Parviz; Kotsopoulos Joanne; Lubinski Jan; Lynch Henry; Kim-Sing Charmaine; Horsman Douglas; Rosen Barry; Isaacs Claudine; Weber Barbara; Foulkes William; Ainsworth Peter; Tung Nadine; Eisen Andrea; Friedman Eitan; Eng Charis; Sun Ping; Narod Steven A
Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers.
International journal of cancer. Journal international du cancer 2006;118(1):103-7.
2006: Foulkes William D
BRCA1 and BRCA2: chemosensitivity, treatment outcomes and prognosis.
Familial cancer 2006;5(2):135-42.
2006: Friedman Eitan; Kotsopoulos Joanne; Lubinski Jan; Lynch Henry T; Ghadirian Parviz; Neuhausen Susan L; Isaacs Claudine; Weber Barbara; Foulkes William D; Moller Pal; Rosen Barry; Kim-Sing Charmaine; Gershoni-Baruch Ruth; Ainsworth Peter; Daly Mary; Tung Nadine; Eisen Andrea; Olopade Olufunmilayo I; Karlan Beth; Saal Howard M; Garber Judy E; Rennert Gad; Gilchrist Dawna; Eng Charis; Offit Kenneth; Osborne Michael; Sun Ping; Narod Steven A;
Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers.
Breast cancer research : BCR 2006;8(2):R15.
2006: Oros Kathleen K; Leblanc Guy; Arcand Suzanna L; Shen Zhen; Perret Chantal; Mes-Masson Anne-Marie; Foulkes William D; Ghadirian Parviz; Provencher Diane; Tonin Patricia N
Haplotype analysis suggest common founders in carriers of the recurrent BRCA2 mutation, 3398delAAAAG, in French Canadian hereditary breast and/ovarian cancer families.
BMC medical genetics 2006;7():23.
2006: McVety Susan; Li Lili; Thiffault Isabelle; Gordon Philip H; Macnamara Elizabeth; Wong Nora; Australie Karlene; Kasprzak Lidia; Chong George; Foulkes William D
The value of multi-modal gene screening in HNPCC in Quebec: three mutations in mismatch repair genes that would have not been correctly identified by genomic DNA sequencing alone.
Familial cancer 2006;5(1):21-8.
2006: Rudkin Teresa M; Hamel Nancy; Galvez Maria; Hogervorst Frans; Gille Johan J P; Møller Pål; Apold Jaran; Foulkes William D
The frequent BRCA1 mutation 1135insA has multiple origins: a haplotype study in different populations.
BMC medical genetics 2006;7():15.
2005: Cullinane Carey A; Lubinski Jan; Neuhausen Susan L; Ghadirian Parviz; Lynch Henry T; Isaacs Claudine; Weber Barbara; Moller Pal; Offit Kenneth; Kim-Sing Charmaine; Friedman Eitan; Randall Susan; Pasini Barbara; Ainsworth Peter; Gershoni-Baruch Ruth; Foulkes William D; Klijn Jan; Tung Nadine; Rennert Gad; Olopade Olufunmilayo; Couch Fergus; Wagner Teresa; Olsson Hakan; Sun Ping; Weitzel Jeffrey N; Narod Steven A
Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers.
International journal of cancer. Journal international du cancer 2005;117(6):988-91.
2005: Eisen Andrea; Lubinski Jan; Klijn Jan; Moller Pal; Lynch Henry T; Offit Kenneth; Weber Barbara; Rebbeck Tim; Neuhausen Susan L; Ghadirian Parviz; Foulkes William D; Gershoni-Baruch Ruth; Friedman Eitan; Rennert Gadi; Wagner Teresa; Isaacs Claudine; Kim-Sing Charmaine; Ainsworth Peter; Sun Ping; Narod Steven A
Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(30):7491-6.
2005: Sun S; Greenwood C M T; Thiffault I; Hamel N; Chong G; Foulkes W D
The HNPCC associated MSH2*1906G-->C founder mutation probably originated between 1440 CE and 1715 CE in the Ashkenazi Jewish population.
Journal of medical genetics 2005;42(10):766-8.
2005: van der Klift Heleen; Wijnen Juul; Wagner Anja; Verkuilen Paul; Tops Carli; Otway Robyn; Kohonen-Corish Maija; Vasen Hans; Oliani Cristina; Barana Daniela; Moller Pal; Delozier-Blanchet Celia; Hutter Pierre; Foulkes William; Lynch Henry; Burn John; Möslein Gabriela; Fodde Riccardo
Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC).
Genes, chromosomes & cancer 2005;44(2):123-38.
2005: McVety S; Younan R; Li L; Gordon P H; Wong N; Foulkes W D; Chong G
Novel genomic insertion-- deletion in MLH1: possible mechanistic role for non-homologous end-joining DNA repair.
Clinical genetics 2005;68(3):234-8.
2005: Soravia Claudio; DeLozier Celia D; Dobbie Zurana; Berthod Claudine Rey; Arrigoni Eviano; Bründler Marie-Anne; Blouin Jean-Louis; Foulkes William D; Hutter Pierre
Double frameshift mutations in APC and MSH2 in the same individual.
International journal of colorectal disease 2005;20(5):466-470.
2005: Kasprzak Lidia; Mesurolle Benoit; Tremblay Francine; Galvez Maria; Halwani Fawaz; Foulkes William D
Invasive breast cancer following bilateral subcutaneous mastectomy in a BRCA2 mutation carrier: a case report and review of the literature.
World journal of surgical oncology 2005;3():52.
2005: Foulkes William D; Hamel Nancy; Oros Kathleen Klein; Tonin Patricia N
BRCA mutations and ductal carcinoma in situ.
JAMA : the journal of the American Medical Association 2005;294(5):553-4.
2005: Kotsopoulos Joanne; Lubinski Jan; Lynch Henry T; Neuhausen Susan L; Ghadirian Parviz; Isaacs Claudine; Weber Barbara; Kim-Sing Charmaine; Foulkes William D; Gershoni-Baruch Ruth; Ainsworth Peter; Friedman Eitan; Daly Mary; Garber Judy E; Karlan Beth; Olopade Olufunmilayo I; Tung Nadine; Saal Howard M; Eisen Andrea; Osborne Michael; Olsson Hakan; Gilchrist Dawna; Sun Ping; Narod Steven A
Age at menarche and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
Cancer causes & control : CCC 2005;16(6):667-74.
2005: Weitzel Jeffrey N; Robson Mark; Pasini Barbara; Manoukian Siranoush; Stoppa-Lyonnet Dominique; Lynch Henry T; McLennan Jane; Foulkes William D; Wagner Teresa; Tung Nadine; Ghadirian Parviz; Olopade Olufunmilayo; Isaacs Claudine; Kim-Sing Charmaine; Møller Pal; Neuhausen Susan L; Metcalfe Kelly; Sun Ping; Narod Steven A
A comparison of bilateral breast cancers in BRCA carriers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(6):1534-8.
2005: Arnes Jarle B; Brunet Jean-Sébastien; Stefansson Ingunn; Bégin Louis R; Wong Nora; Chappuis Pierre O; Akslen Lars A; Foulkes William D
Placental cadherin and the basal epithelial phenotype of BRCA1-related breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(11):4003-11.
2005: Collett Karin; Stefansson Ingunn M; Eide Johan; Braaten Audun; Wang Hege; Eide Geir Egil; Thoresen Steinar Ø; Foulkes William D; Akslen Lars A
A basal epithelial phenotype is more frequent in interval breast cancers compared with screen detected tumors.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(5):1108-12.
2005: Makriyianni I; Hamel N; Ward S; Foulkes W D; Graw S
BRCA1:185delAG found in the San Luis Valley probably originated in a Jewish founder.
Journal of medical genetics 2005;42(5):e27.
2005: Chappuis P O; Donato E; Goffin J R; Wong N; Bégin L R; Kapusta L R; Brunet J-S; Porter P; Foulkes W D
Cyclin E expression in breast cancer: predicting germline BRCA1 mutations, prognosis and response to treatment.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(5):735-42.
2005: Rudkin Teresa M; Foulkes William D
BRCA2: breaks, mistakes and failed separations.
Trends in molecular medicine 2005;11(4):145-8.
2005: Metcalfe Kelly A; Lynch Henry T; Ghadirian Parviz; Tung Nadine; Olivotto Ivo A; Foulkes William D; Warner Ellen; Olopade Olufunmilayo; Eisen Andrea; Weber Barbara; McLennan Jane; Sun Ping; Narod Steven A
The risk of ovarian cancer after breast cancer in BRCA1 and BRCA2 carriers.
Gynecologic oncology 2005;96(1):222-6.
2005: Kotsopoulos Joanne; Olopado Olufunmilayo I; Ghadirian Parviz; Lubinski Jan; Lynch Henry T; Isaacs Claudine; Weber Barbara; Kim-Sing Charmaine; Ainsworth Peter; Foulkes William D; Eisen Andrea; Sun Ping; Narod Steven A
Changes in body weight and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
Breast cancer research : BCR 2005;7(5):R833-43.
2004: Oros Kathleen K; Ghadirian Parviz; Greenwood Celia M T; Perret Chantal; Shen Zhen; Paredes Yosabeth; Arcand Suzanna L; Mes-Masson Anne-Marie; Narod Steven A; Foulkes William D; Provencher Diane; Tonin Patricia N
Significant proportion of breast and/or ovarian cancer families of French Canadian descent harbor 1 of 5 BRCA1 and BRCA2 mutations.
International journal of cancer. Journal international du cancer 2004;112(3):411-9.
2004: Thiffault I; Schwartz C E; Der Kaloustian V; Foulkes W D
Mutation analysis of the tumor suppressor PTEN and the glypican 3 (GPC3) gene in patients diagnosed with Proteus syndrome.
American journal of medical genetics. Part A 2004;130A(2):123-7.
2004: Thiffault I; Foulkes W D; Marcus V A; Farber D; Kasprzak L; MacNamara E; Wong N; Hutter P; Radice P; Bertario L; Chong G
Putative common origin of two MLH1 mutations in Italian-Quebec hereditary non-polyposis colorectal cancer families.
Clinical genetics 2004;66(2):137-43.
2004: Jernström H; Lubinski J; Lynch H T; Ghadirian P; Neuhausen S; Isaacs C; Weber B L; Horsman D; Rosen B; Foulkes W D; Friedman E; Gershoni-Baruch R; Ainsworth P; Daly M; Garber J; Olsson H; Sun P; Narod S A
Breast-feeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
Journal of the National Cancer Institute 2004;96(14):1094-8.
2004: Al Moustafa Ala-Eddin; Foulkes William D; Wong Annick; Jallal Houda; Batist Gerald; Yu Qunyan; Herlyn Meenhard; Sicinski Piotr; Alaoui-Jamali Moulay A
Cyclin D1 is essential for neoplastic transformation induced by both E6/E7 and E6/E7/ErbB-2 cooperation in normal cells.
Oncogene 2004;23(30):5252-6.
2004: Metcalfe Kelly; Lynch Henry T; Ghadirian Parviz; Tung Nadine; Olivotto Ivo; Warner Ellen; Olopade Olufunmilayo I; Eisen Andrea; Weber Barbara; McLennan Jane; Sun Ping; Foulkes William D; Narod Steven A
Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(12):2328-35.
2004: Ghadirian Parviz; Lubinski Jan; Lynch Henry; Neuhausen Susan L; Weber Barbara; Isaacs Claudine; Baruch Ruth-Gershoni; Randall Susan; Ainsworth Peter; Friedman Eitan; Horsman Douglas; Tonin Patricia; Foulkes William D; Tung Nadine; Sun Ping; Narod Steven A
Smoking and the risk of breast cancer among carriers of BRCA mutations.
International journal of cancer. Journal international du cancer 2004;110(3):413-6.
2004: Foulkes William D; Metcalfe Kelly; Sun Ping; Hanna Wedad M; Lynch Henry T; Ghadirian Parviz; Tung Nadine; Olopade Olufunmilayo I; Weber Barbara L; McLennan Jane; Olivotto Ivo A; Bégin Louis R; Narod Steven A
Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: the influence of age, grade, and histological type.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(6):2029-34.
2004: Foulkes William D; Brunet Jean-Sébastien; Stefansson Ingunn M; Straume Oddbjørn; Chappuis Pierre O; Bégin Louis R; Hamel Nancy; Goffin John R; Wong Nora; Trudel Michel; Kapusta Linda; Porter Peggy; Akslen Lars A
The prognostic implication of the basal-like (cyclin E high/p27 low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer.
Cancer research 2004;64(3):830-5.
2004: Thiffault I; Hamel N; Pal T; McVety S; Marcus V A; Farber D; Cowie S; Deschênes J; Meschino W; Odefrey F; Goldgar D; Graham T; Narod S; Watters A K; MacNamara E; Du Sart D; Chong G; Foulkes W D
Germline truncating mutations in both MSH2 and BRCA2 in a single kindred.
British journal of cancer 2004;90(2):483-91.
2004: Foulkes W D
BRCA1 functions as a breast stem cell regulator.
Journal of medical genetics 2004;41(1):1-5.
2004: Al Moustafa Ala-Eddin; Foulkes William D; Benlimame Naciba; Wong Annick; Yen Lily; Bergeron Josée; Batist Gerald; Alpert Lesley; Alaoui-Jamali Moulay A
E6/E7 proteins of HPV type 16 and ErbB-2 cooperate to induce neoplastic transformation of primary normal oral epithelial cells.
Oncogene 2004;23(2):350-8.
2004: Robson Mark E; Chappuis Pierre O; Satagopan Jaya; Wong Nora; Boyd Jeff; Goffin John R; Hudis Clifford; Roberge David; Norton Larry; Bégin Louis R; Offit Kenneth; Foulkes William D
A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment.
Breast cancer research : BCR 2004;6(1):R8-R17.
2003: Foulkes William D; Metcalfe Kelly; Hanna Wedad; Lynch Henry T; Ghadirian Parviz; Tung Nadine; Olopade Olofunmilayo; Weber Barbara; McLennan Jane; Olivotto Ivo A; Sun Ping; Chappuis Pierre O; Bégin Louis R; Brunet Jean-Sébastien; Narod Steven A
Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma.
Cancer 2003;98(8):1569-77.
2003: Foulkes William D; Stefansson Ingunn M; Chappuis Pierre O; Bégin Louis R; Goffin John R; Wong Nora; Trudel Michel; Akslen Lars A
Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer.
Journal of the National Cancer Institute 2003;95(19):1482-5.
2003: Goffin J R; Straume O; Chappuis P O; Brunet J-S; Bégin L R; Hamel N; Wong N; Akslen L A; Foulkes W D
Glomeruloid microvascular proliferation is associated with p53 expression, germline BRCA1 mutations and an adverse outcome following breast cancer.
British journal of cancer 2003;89(6):1031-4.
2003: Hamel Nancy; Kotar Kimberley; Foulkes William D
Founder mutations in BRCA1/2 are not frequent in Canadian Ashkenazi Jewish men with prostate cancer.
BMC medical genetics 2003;4():7.
2003: Pollak Michael N; Foulkes William D
Challenges to cancer control by screening.
Nature reviews. Cancer 2003;3(4):297-303.
2003: Kotar K; Hamel N; Thiffault I; Foulkes W D
The RNASEL 471delAAAG allele and prostate cancer in Ashkenazi Jewish men.
Journal of medical genetics 2003;40(3):e22.
2003: Goffin John R; Chappuis Pierre O; Bégin Louis R; Wong Nora; Brunet Jean-Sébastien; Hamel Nancy; Paradis Ann-Josée; Boyd Jeff; Foulkes William D
Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma: 10-year follow up data.
Cancer 2003;97(3):527-36.
2003: Karakiewicz Pierre I; Foulkes William; Tanguay Simon; Elhilali Mostafa M; Aprikian Armen G
Familial prostate and breast cancer in men treated with prostatectomy for prostate cancer: a population based case-control study.
The Journal of urology 2003;169(1):240-4.
2002: Straume Oddbjørn; Chappuis Pierre O; Salvesen Helga B; Halvorsen Ole J; Haukaas Svein A; Goffin John R; Bégin Louis R; Foulkes William D; Akslen Lars A
Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers.
Cancer research 2002;62(23):6808-11.
2002: Foulkes William D; Goffin John; Brunet Jean-Sébastien; Bégin Louis R; Wong Nora; Chappuis Pierre O
Tamoxifen may be an effective adjuvant treatment for BRCA1-related breast cancer irrespective of estrogen receptor status.
Journal of the National Cancer Institute 2002;94(19):1504-6.
2002: Cremin Carol; Wong Nora; Buzaglo Karen; Paradis Ann-Josée; Foulkes William
Nonovarian pelvic cancers in BRCA1/2 mutation carriers and the BRCAPRO statistical model.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(18):3936; author reply 3936-7.
2002: Ah Mew N; Hamel N; Galvez M; Al-Saffar M; Foulkes W D
Haplotype analysis of a BRCA1: 185delAG mutation in a Chilean family supports its Ashkenazi origins.
Clinical genetics 2002;62(2):151-6.
2002: Chappuis P O; Goffin J; Wong N; Perret C; Ghadirian P; Tonin P N; Foulkes W D
A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancer.
Journal of medical genetics 2002;39(8):608-10.
2002: Foulkes W D; Brunet J S; Wong N; Goffin J; Chappuis P O
Change in the penetrance of founder BRCA1/2 mutations? A retrospective cohort study.
Journal of medical genetics 2002;39(6):407-9.
2002: Laaziri Khalid; Sutton M; Ghadirian P; Scott A S; Paradis A J; Tonin P N; Foulkes W D
Is there a correlation between the structure of hair and breast cancer or BRCA1/2 mutations?
Physics in medicine and biology 2002;47(10):1623-32.
2002: Hutter P; Wijnen J; Rey-Berthod C; Thiffault I; Verkuijlen P; Farber D; Hamel N; Bapat B; Thibodeau S N; Burn J; Wu J; MacNamara E; Heinimann K; Chong G; Foulkes W D
An MLH1 haplotype is over-represented on chromosomes carrying an HNPCC predisposing mutation in MLH1.
Journal of medical genetics 2002;39(5):323-7.
2002: Al Moustafa Ala-Eddin; Alaoui-Jamali Moulay A; Batist Gerald; Hernandez-Perez Maite; Serruya Corinne; Alpert Lesley; Black Martin J; Sladek Robert; Foulkes William D
Identification of genes associated with head and neck carcinogenesis by cDNA microarray comparison between matched primary normal epithelial and squamous carcinoma cells.
Oncogene 2002;21(17):2634-40.
2002: Andermann Anne; Thiffault Isabelle; Wong Nora; Gordon Philip; MacNamara Elizabeth; Chong George; Foulkes William
Multimodal molecular screening is required to improve the sensitivity of MLH1 and MSH2 mutation analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(6):1705-7.
2002: Foulkes William D
Of mice and women.
Cancer cell 2002;1(1):11-2.
2002: Ghadirian Parviz; Liu Geoffrey; Gallinger Steven; Schmocker Beverly; Paradis Anne-Josee; Lal Geeta; Brunet Jean-Sebastien; Foulkes William D; Narod Steven A
Risk of pancreatic cancer among individuals with a family history of cancer of the pancreas.
International journal of cancer. Journal international du cancer 2002;97(6):807-10.
2002: Yuan Zi Qiang; Gottlieb Bruce; Beitel Lenore K; Wong Nora; Gordon Philip H; Wang Qing; Puisieux Alain; Foulkes William D; Trifiro Mark
Polymorphisms and HNPCC: PMS2-MLH1 protein interactions diminished by single nucleotide polymorphisms.
Human mutation 2002;19(2):108-13.
2002: Hébert-Blouin Marie-Noël; Koufogianis Vayia; Gillett Peter; Foulkes William D
Fallopian tube cancer in a BRCA1 mutation carrier: rapid development and failure of screening.
American journal of obstetrics and gynecology 2002;186(1):53-4.
2002: Chappuis Pierre O; Foulkes William D
Risk assessment & genetic testing.
Cancer treatment and research 2002;107():29-59.
2001: Goffin J; Chappuis P O; Wong N; Foulkes W D
Re: Magnetic resonance imaging and mammography in women with a hereditary risk of breast cancer.
Journal of the National Cancer Institute 2001;93(22):1754-5.
2001: Foulkes W D; Rosenblatt J; Chappuis P O
The contribution of inherited factors to the clinicopathological features and behavior of breast cancer.
Journal of mammary gland biology and neoplasia 2001;6(4):453-65.
2001: Runnebaum I B; Wang-Gohrke S; Vesprini D; Kreienberg R; Lynch H; Moslehi R; Ghadirian P; Weber B; Godwin A K; Risch H; Garber J; Lerman C; Olopade O I; Foulkes W D; Karlan B; Warner E; Rosen B; Rebbeck T; Tonin P; Dubé M P; Kieback D G; Narod S A
Progesterone receptor variant increases ovarian cancer risk in BRCA1 and BRCA2 mutation carriers who were never exposed to oral contraceptives.
Pharmacogenetics 2001;11(7):635-8.
2001: Chappuis P O; Hamel N; Paradis A J; Deschênes J; Robidoux A; Potvin C; Cantin J; Tonin P; Ghadirian P; Foulkes W D
Prevalence of founder BRCA1 and BRCA2 mutations in unselected French Canadian women with breast cancer.
Clinical genetics 2001;59(6):418-23.
2001: Greenblatt M S; Chappuis P O; Bond J P; Hamel N; Foulkes W D
TP53 mutations in breast cancer associated with BRCA1 or BRCA2 germ-line mutations: distinctive spectrum and structural distribution.
Cancer research 2001;61(10):4092-7.
2001: Tonin P N; Perret C; Lambert J A; Paradis A J; Kantemiroff T; Benoît M H; Martin G; Foulkes W D; Ghadirian P
Founder BRCA1 and BRCA2 mutations in early-onset French Canadian breast cancer cases unselected for family history.
International journal of cancer. Journal international du cancer 2001;95(3):189-93.
2001: Rabelo R; Foulkes W; Gordon P H; Wong N; Yuan Z Q; MacNamara E; Chong G; Pinsky L; Lasko D
Role of molecular diagnostic testing in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer families.
Diseases of the colon and rectum 2001;44(3):437-46.
2001: Wong N; Lasko D; Rabelo R; Pinsky L; Gordon P H; Foulkes W
Genetic counseling and interpretation of genetic tests in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer.
Diseases of the colon and rectum 2001;44(2):271-9.
2001: Chappuis P O; Hamel N; Paradis A J; Deschênes J; Tonin P N; Ghadirian P; Foulkes W D
Re: Population-based study of BRCA1 and BRCA2 mutations in 1035 unselected Finnish breast cancer patients.
Journal of the National Cancer Institute 2001;93(2):152-4.
2001: Pal T; Hamel N; Vesprini D; Sanders K; Mitchell M; Quercia N; Ng Cheong N; Murray A; Foulkes W; Narod S A
Double primary cancers of the breast and thyroid in women: molecular analysis and genetic implications.
Familial cancer 2001;1(1):17-24.
2001: Manning A P; Abelovich D; Ghadirian P; Lambert J A; Frappier D; Provencher D; Robidoux A; Peretz T; Narod S A; Mes-Masson A M; Foulkes W D; Wang T; Morgan K; Fujiwara T M; Tonin P N
Haplotype analysis of BRCA2 8765delAG mutation carriers in French Canadian and Yemenite Jewish hereditary breast cancer families.
Human heredity 2001;52(2):116-20.
2000: Chappuis P O; Kapusta L; Bégin L R; Wong N; Brunet J S; Narod S A; Slingerland J; Foulkes W D
Germline BRCA1/2 mutations and p27(Kip1) protein levels independently predict outcome after breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(24):4045-52.
2000: Metcalfe K A; Liede A; Hoodfar E; Scott A; Foulkes W D; Narod S A
An evaluation of needs of female BRCA1 and BRCA2 carriers undergoing genetic counselling.
Journal of medical genetics 2000;37(11):866-74.
2000: Hamel N; Karimi S; Hébert-Blouin M N; Brunet J S; Gilfix B; Ghadirian P; Black M J; Narod S A; Foulkes W D
Increased risk of head and neck cancer in association with GSTT1 nullizygosity for individuals with low exposure to tobacco.
International journal of cancer. Journal international du cancer 2000;87(3):452-4.
2000: Chappuis P O; Nethercot V; Foulkes W D
Clinico-pathological characteristics of BRCA1- and BRCA2-related breast cancer.
Seminars in surgical oncology 2000;18(4):287-95.
2000: Liu G; Ghadirian P; Vesprini D; Hamel N; Paradis A J; Lal G; Gallinger S; Narod S A; Foulkes W D
Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma.
British journal of cancer 2000;82(10):1646-9.
2000: Foulkes W D; Chappuis P O; Wong N; Brunet J S; Vesprini D; Rozen F; Yuan Z Q; Pollak M N; Kuperstein G; Narod S A; Bégin L R
Primary node negative breast cancer in BRCA1 mutation carriers has a poor outcome.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(3):307-13.
2000: Kuperstein G; Foulkes W D; Ghadirian P; Hakimi J; Narod S A
A rapid fluorescent multiplexed-PCR analysis (FMPA) for founder mutations in the BRCA1 and BRCA2 genes.
Clinical genetics 2000;57(3):213-20.
2000: Hamel N; Black M J; Ghadirian P; Foulkes W D
No association between P53 codon 72 polymorphism and risk of squamous cell carcinoma of the head and neck.
British journal of cancer 2000;82(4):757-9.
1999: Hamel N; Manning A; Black M J; Tonin P N; Foulkes W D
An absence of founder BRCA2 mutations in individuals with squamous cell carcinoma of the head and neck.
International journal of cancer. Journal international du cancer 1999;83(6):803-4.
1999: Foulkes W D; Brunet J S; Warner E; Goodwin P J; Meschino W; Narod S A; Goss P E; Glendon G
The importance of a family history of breast cancer in predicting the presence of a BRCA mutation.
American journal of human genetics 1999;65(6):1776-9.
1999: Jernström H; Lerman C; Ghadirian P; Lynch H T; Weber B; Garber J; Daly M; Olopade O I; Foulkes W D; Warner E; Brunet J S; Narod S A
Pregnancy and risk of early breast cancer in carriers of BRCA1 and BRCA2.
Lancet 1999;354(9193):1846-50.
1999: Yuan Z Q; Bégin L R; Wong N; Brunet J S; Trifiro M; Gordon P H; Pinsky L; Foulkes W D
The effect of the I1307K APC polymorphism on the clinicopathological features and natural history of breast cancer.
British journal of cancer 1999;81(5):850-4.
1999: Chappuis P O; Rosenblatt J; Foulkes W D
The influence of familial and hereditary factors on the prognosis of breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(10):1163-70.
1999: Yuan Z Q; Wong N; Foulkes W D; Alpert L; Manganaro F; Andreutti-Zaugg C; Iggo R; Anthony K; Hsieh E; Redston M; Pinsky L; Trifiro M; Gordon P H; Lasko D
A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screening.
Journal of medical genetics 1999;36(10):790-3.
1999: Chappuis P O; Narod S A; Foulkes W D
Screening for ovarian cancer.
Lancet 1999;354(9177):509-10.
1999: Warner E; Foulkes W; Goodwin P; Meschino W; Blondal J; Paterson C; Ozcelik H; Goss P; Allingham-Hawkins D; Hamel N; Di Prospero L; Contiga V; Serruya C; Klein M; Moslehi R; Honeyford J; Liede A; Glendon G; Brunet J S; Narod S
Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancer.
Journal of the National Cancer Institute 1999;91(14):1241-7.
1999: Kasprzak L; Foulkes W D; Shelling A N
Forth nightly review: hereditary ovarian carcinoma.
BMJ (Clinical research ed.) 1999;318(7186):786-9.
1998: Pal T; Flanders T; Mitchell-Lehman M; MacMillan A; Brunet J S; Narod S A; Foulkes W D
Genetic implications of double primary cancers of the colorectum and endometrium.
Journal of medical genetics 1998;35(12):978-84.
1998: Tonin P N; Mes-Masson A M; Futreal P A; Morgan K; Mahon M; Foulkes W D; Cole D E; Provencher D; Ghadirian P; Narod S A
Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families.
American journal of human genetics 1998;63(5):1341-51.
1998: Yuan Z Q; Kasprzak L; Gordon P H; Pinsky L; Foulkes W D
I1307K APC and hMLH1 mutations in a non-Jewish family with hereditary non-polyposis colorectal cancer.
Clinical genetics 1998;54(4):368-70.
1998: Foulkes W D
BRCA1 and BRCA2: penetrating the clinical arena.
Lancet 1998;352(9137):1325-6.
1998: Foulkes W D; Wong N; Brunet J S; Narod S A
BRCA mutations and survival in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(9):3206-8.
1998: Redston M; Nathanson K L; Yuan Z Q; Neuhausen S L; Satagopan J; Wong N; Yang D; Nafa D; Abrahamson J; Ozcelik H; Antin-Ozerkis D; Andrulis I; Daly M; Pinsky L; Schrag D; Gallinger S; Kaback M; King M C; Woodage T; Brody L C; Godwin A; Warner E; Weber B; Foulkes W; Offit K
The APCI1307K allele and breast cancer risk.
Nature genetics 1998;20(1):13-4.
1998: Godard B; Foulkes W D; Provencher D; Brunet J S; Tonin P N; Mes-Masson A M; Narod S A; Ghadirian P
Risk factors for familial and sporadic ovarian cancer among French Canadians: a case-control study.
American journal of obstetrics and gynecology 1998;179(2):403-10.
1998: Foulkes W D; Wong N; Rozen F; Brunet J S; Narod S A
Survival of patients with breast cancer and BRCA1 mutations.
Lancet 1998;351(9112):1359-60.
1998: Brunet J S; Ghadirian P; Rebbeck T R; Lerman C; Garber J E; Tonin P N; Abrahamson J; Foulkes W D; Daly M; Wagner-Costalas J; Godwin A; Olopade O I; Moslehi R; Liede A; Futreal P A; Weber B L; Lenoir G M; Lynch H T; Narod S A
Effect of smoking on breast cancer in carriers of mutant BRCA1 or BRCA2 genes.
Journal of the National Cancer Institute 1998;90(10):761-6.
1998: Liede A; Tonin P N; Sun C C; Serruya C; Daly M B; Narod S A; Foulkes W D
Is hereditary site-specific ovarian cancer a distinct genetic condition?
American journal of medical genetics 1998;75(1):55-8.
1998: Pollock P M; Spurr N; Bishop T; Newton-Bishop J; Gruis N; van der Velden P A; Goldstein A M; Tucker M A; Foulkes W D; Barnhill R; Haber D; Fountain J; Hayward N K
Haplotype analysis of two recurrent CDKN2A mutations in 10 melanoma families: evidence for common founders and independent mutations.
Human mutation 1998;11(6):424-31.
1997: Foulkes W D; Wong N; Brunet J S; Bégin L R; Zhang J C; Martinez J J; Rozen F; Tonin P N; Narod S A; Karp S E; Pollak M N
Germ-line BRCA1 mutation is an adverse prognostic factor in Ashkenazi Jewish women with breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(12 Pt 1):2465-9.
1997: Sun S; Pollock P M; Liu L; Karimi S; Jothy S; Milner B J; Renwick A; Lassam N J; Hayward N K; Hogg D; Narod S A; Foulkes W D
CDKN2A mutation in a non-FAMMM kindred with cancers at multiple sites results in a functionally abnormal protein.
International journal of cancer. Journal international du cancer 1997;73(4):531-6.
1997: Druker H A; Kasprzak L; Bégin L R; Jothy S; Narod S A; Foulkes W D
Family with Graves disease, multinodular goiter, nonmedullary thyroid carcinoma, and alveolar rhabdomyosarcoma.
American journal of medical genetics 1997;72(1):30-3.
1997: Foulkes W D; Buu P N; Filiatrault D; Leclerc J M; Narod S A
Excess of congenital abnormalities in French-Canadian children with neuroblastoma: a case series study from Montréal.
Medical and pediatric oncology 1997;29(4):272-9.
1997: Karp S E; Tonin P N; Bégin L R; Martinez J J; Zhang J C; Pollak M N; Foulkes W D
Influence of BRCA1 mutations on nuclear grade and estrogen receptor status of breast carcinoma in Ashkenazi Jewish women.
Cancer 1997;80(3):435-41.
1997: Brunet J S; Narod S A; Tonin P; Foulkes W D
BRCA1 mutations and survival in women with ovarian cancer.
The New England journal of medicine 1997;336(17):1256; author reply 1256-7.
1997: Foulkes W D; Flanders T Y; Pollock P M; Hayward N K
The CDKN2A (p16) gene and human cancer.
Molecular medicine (Cambridge, Mass.) 1997;3(1):5-20.
1996: Cutler C; Foulkes W D; Brunet J S; Flanders T Y; Shibata H; Narod S A
Cutaneous malignant melanoma in women is uncommonly associated with a family history of melanoma in first-degree relatives: a case-control study.
Melanoma research 1996;6(6):435-40.
1996: Flanders T Y; Foulkes W D
Pancreatic adenocarcinoma: epidemiology and genetics.
Journal of medical genetics 1996;33(11):889-98.
1996: Tonin P; Weber B; Offit K; Couch F; Rebbeck T R; Neuhausen S; Godwin A K; Daly M; Wagner-Costalos J; Berman D; Grana G; Fox E; Kane M F; Kolodner R D; Krainer M; Haber D A; Struewing J P; Warner E; Rosen B; Lerman C; Peshkin B; Norton L; Serova O; Foulkes W D; Garber J E
Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families.
Nature medicine 1996;2(11):1179-83.
1996: Foulkes W D; Brunet J S; Sieh W; Black M J; Shenouda G; Narod S A
Familial risks of squamous cell carcinoma of the head and neck: retrospective case-control study.
BMJ (Clinical research ed.) 1996;313(7059):716-21.
1996: Foulkes W D; Bolduc N; Lambert D; Ginsburg O; Olien L; Yandell D W; Tonin P N; Narod S A
Increased incidence of cancer in first degree relatives of women with double primary carcinomas of the breast and colon.
Journal of medical genetics 1996;33(7):534-9.
1996: Phelan C M; Lancaster J M; Tonin P; Gumbs C; Cochran C; Carter R; Ghadirian P; Perret C; Moslehi R; Dion F; Faucher M C; Dole K; Karimi S; Foulkes W; Lounis H; Warner E; Goss P; Anderson D; Larsson C; Narod S A; Futreal P A
Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families.
Nature genetics 1996;13(1):120-2.
1996: Foulkes W D; Narod S A
Screening for cancer in high-risk families.
Cancer treatment and research 1996;86():165-82.
1995: Foulkes W D; Brunet J S; Kowalski L P; Narod S A; Franco E L
Family history of cancer is a risk factor for squamous cell carcinoma of the head and neck in Brazil: a case-control study.
International journal of cancer. Journal international du cancer 1995;63(6):769-73.
1995: Foulkes W D
A tale of four syndromes: familial adenomatous polyposis, Gardner syndrome, attenuated APC and Turcot syndrome.
QJM : monthly journal of the Association of Physicians 1995;88(12):853-63.
1995: Foulkes W D; Stamp G W; Afzal S; Lalani N; McFarlane C P; Trowsdale J; Campbell I G
MDM2 overexpression is rare in ovarian carcinoma irrespective of TP53 mutation status.
British journal of cancer 1995;72(4):883-8.
1995: Foulkes W; Glendon G; Narod S
Family history and risk of ovarian cancer.
JAMA : the journal of the American Medical Association 1995;274(5):383.

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