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Jay Fox
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Chemicals & Drugs
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19
Shannon, John
14
Serrano, Solange
8
Jia, Li-Guo
8
Kamiguti, Aura
8
Gutiérrez, José María
8
Theakston, David
7
Zigrino, Paola
7
Dragulev, Bojan
7
Mauch, Cornelia
6
Pinto, Antônio
6
Bao, Yongde
5
Nischt, Roswitha
4
Rucavado, Alexandra
4
Chapman, Martin
4
Escalante, Teresa
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All Publications
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2009: Escalante Teresa; Rucavado Alexandra; Pinto Antonio F M; Terra Renata M S; Gutiérrez José María; Fox Jay W
Wound exudate as a proteomic window to reveal different mechanisms of tissue damage by snake venom toxins.
Journal of proteome research 2009;8(11):5120-31.
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2009: Terra Renata M S; Pinto Antônio F M; Guimarães Jorge A; Fox Jay W
Proteomic profiling of snake venom metalloproteinases (SVMPs): insights into venom induced pathology.
Toxicon : official journal of the International Society on Toxinology 2009;54(6):836-44.
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2009: Zigrino Paola; Kuhn Isolde; Bäuerle Tobias; Zamek Jan; Fox Jay W; Neumann Susanne; Licht Alexander; Schorpp-Kistner Marina; Angel Peter; Mauch Cornelia
Stromal expression of MMP-13 is required for melanoma invasion and metastasis.
The Journal of investigative dermatology 2009;129(11):2686-93.
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2009: Li Ling; Dragulev Bojan; Zigrino Paola; Mauch Cornelia; Fox Jay W
The invasive potential of human melanoma cell lines correlates with their ability to alter fibroblast gene expression in vitro and the stromal microenvironment in vivo.
International journal of cancer. Journal international du cancer 2009;125(8):1796-804.
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2009: Fox Jay W; Serrano Solange M T
Timeline of key events in snake venom metalloproteinase research.
Journal of proteomics 2009;72(2):200-9.
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2008: Fox Jay W; Serrano Solange M T
Insights into and speculations about snake venom metalloproteinase (SVMP) synthesis, folding and disulfide bond formation and their contribution to venom complexity.
The FEBS journal 2008;275(12):3016-30.
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2008: Pinto Antônio F M; Dragulev Bojan; Guimarães Jorge A; Fox Jay W
Novel perspectives on the pathogenesis of Lonomia obliqua caterpillar envenomation based on assessment of host response by gene expression analysis.
Toxicon : official journal of the International Society on Toxinology 2008;51(6):1119-28.
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2008: Fox Jay W; Serrano Solange M T
Exploring snake venom proteomes: multifaceted analyses for complex toxin mixtures.
Proteomics 2008;8(4):909-20.
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2007: Mayhew Mark W; Jeffery Erin D; Sherman Nicholas E; Nelson Kristina; Polefrone Joy M; Pratt Stephen J; Shabanowitz Jeffrey; Parsons J Thomas; Fox Jay W; Hunt Donald F; Horwitz Alan F
Identification of phosphorylation sites in betaPIX and PAK1.
Journal of cell science 2007;120(Pt 22):3911-8.
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2007: Zigrino Paola; Steiger Julia; Fox Jay W; Löffek Stefanie; Schild Alexander; Nischt Roswitha; Mauch Cornelia
Role of ADAM-9 disintegrin-cysteine-rich domains in human keratinocyte migration.
The Journal of biological chemistry 2007;282(42):30785-93.
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2007: Pinto A F M; Ma L; Dragulev B; Guimaraes J A; Fox J W
Use of SILAC for exploring sheddase and matrix degradation of fibroblasts in culture by the PIII SVMP atrolysin A: identification of two novel substrates with functional relevance.
Archives of biochemistry and biophysics 2007;465(1):11-5.
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2007: Serrano Solange M T; Wang Deyu; Shannon John D; Pinto Antonio F M; Polanowska-Grabowska Renata K; Fox Jay W
Interaction of the cysteine-rich domain of snake venom metalloproteinases with the A1 domain of von Willebrand factor promotes site-specific proteolysis of von Willebrand factor and inhibition of von Willebrand factor-mediated platelet aggregation.
The FEBS journal 2007;274(14):3611-21.
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2007: Goldfinger Lawrence E; Ptak Celeste; Jeffery Erin D; Shabanowitz Jeffrey; Han Jaewon; Haling Jacob R; Sherman Nicholas E; Fox Jay W; Hunt Donald F; Ginsberg Mark H
An experimentally derived database of candidate Ras-interacting proteins.
Journal of proteome research 2007;6(5):1806-11.
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2007: Dragulev Bojan; Bao Yongde; Ramos-Cerrillo Blanca; Vazquez Hilda; Olvera Alejandro; Stock Roberto; Algaron Alejandro; Fox Jay W
Upregulation of IL-6, IL-8, CXCL1, and CXCL2 dominates gene expression in human fibroblast cells exposed to Loxosceles reclusa sphingomyelinase D: insights into spider venom dermonecrosis.
The Journal of investigative dermatology 2007;127(5):1264-6.
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2007: Clines Gregory A; Mohammad Khalid S; Bao Yongde; Stephens Owen W; Suva Larry J; Shaughnessy John D; Fox Jay W; Chirgwin John M; Guise Theresa A
Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formation.
Molecular endocrinology (Baltimore, Md.) 2007;21(2):486-98.
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2007: Pinto Antonio F M; Terra Renata M S; Guimaraes Jorge A; Fox Jay W
Mapping von Willebrand factor A domain binding sites on a snake venom metalloproteinase cysteine-rich domain.
Archives of biochemistry and biophysics 2007;457(1):41-6.
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2007: Fox Jay W; Serrano Solange M T
Approaching the golden age of natural product pharmaceuticals from venom libraries: an overview of toxins and toxin-derivatives currently involved in therapeutic or diagnostic applications.
Current pharmaceutical design 2007;13(28):2927-34.
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2006: Serrano Solange M T; Kim Junho; Wang Deyu; Dragulev Bojan; Shannon John D; Mann Henning H; Veit Guido; Wagener Raimund; Koch Manuel; Fox Jay W
The cysteine-rich domain of snake venom metalloproteinases is a ligand for von Willebrand factor A domains: role in substrate targeting.
The Journal of biological chemistry 2006;281(52):39746-56.
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2006: Escalante Teresa; Shannon John; Moura-da-Silva Ana M; Gutiérrez José María; Fox Jay W
Novel insights into capillary vessel basement membrane damage by snake venom hemorrhagic metalloproteinases: a biochemical and immunohistochemical study.
Archives of biochemistry and biophysics 2006;455(2):144-53.
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2006: Chen Lanlin; Hellmark Thomas; Pedchenko Vadim; Hudson Billy G; Pusey Charles D; Fox Jay W; Bolton W Kline
A nephritogenic peptide induces intermolecular epitope spreading on collagen IV in experimental autoimmune glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2006;17(11):3076-81.
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2006: Mayhew Mark W; Webb Donna J; Kovalenko Mykola; Whitmore Leanna; Fox Jay W; Horwitz Alan F
Identification of protein networks associated with the PAK1-betaPIX-GIT1-paxillin signaling complex by mass spectrometry.
Journal of proteome research 2006;5(9):2417-23.
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2006: Pinto Antônio F M; Terra Renata M S; Guimarães Jorge A; Kashiwagi Masahide; Nagase Hideaki; Serrano Solange M T; Fox Jay W
Structural features of the reprolysin atrolysin C and tissue inhibitors of metalloproteinases (TIMPs) interaction.
Biochemical and biophysical research communications 2006;347(3):641-8.
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2006: Fox Jay W; Ma Li; Nelson Kristina; Sherman Nicholas E; Serrano Solange M T
Comparison of indirect and direct approaches using ion-trap and Fourier transform ion cyclotron resonance mass spectrometry for exploring viperid venom proteomes.
Toxicon : official journal of the International Society on Toxinology 2006;47(6):700-14.
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2005: Serrano Solange M T; Jia Li-Guo; Wang Deyu; Shannon John D; Fox Jay W
Function of the cysteine-rich domain of the haemorrhagic metalloproteinase atrolysin A: targeting adhesion proteins collagen I and von Willebrand factor.
The Biochemical journal 2005;391(Pt 1):69-76.
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2005: Zigrino Paola; Mauch Cornelia; Fox Jay W; Nischt Roswitha
Adam-9 expression and regulation in human skin melanoma and melanoma cell lines.
International journal of cancer. Journal international du cancer 2005;116(6):853-9.
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2005: Gallagher Paul; Bao Yongde; Serrano Solange M T; Laing Gavin D; Theakston R David G; Gutiérrez José M; Escalante Teresa; Zigrino Paola; Moura-da-Silva Ana M; Nischt Roswitha; Mauch Cornelia; Moskaluk Christopher; Fox Jay W
Role of the snake venom toxin jararhagin in proinflammatory pathogenesis: in vitro and in vivo gene expression analysis of the effects of the toxin.
Archives of biochemistry and biophysics 2005;441(1):1-15.
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2005: Bolton Warren Kline; Chen Lanlin; Hellmark Thomas; Wieslander Jörgen; Fox Jay W
Epitope spreading and autoimmune glomerulonephritis in rats induced by a T cell epitope of Goodpasture's antigen.
Journal of the American Society of Nephrology : JASN 2005;16(9):2657-66.
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2005: Fox Jay W; Serrano Solange M T
Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinases.
Toxicon : official journal of the International Society on Toxinology 2005;45(8):969-85.
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2005: Gallagher Paul G; Bao Yongde; Prorock Alyson; Zigrino Paola; Nischt Roswitha; Politi Vincenzo; Mauch Cornelia; Dragulev Bojan; Fox Jay William
Gene expression profiling reveals cross-talk between melanoma and fibroblasts: implications for host-tumor interactions in metastasis.
Cancer research 2005;65(10):4134-46.
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2005: Serrano Solange M T; Shannon John D; Wang Deyu; Camargo Antonio C M; Fox Jay W
A multifaceted analysis of viperid snake venoms by two-dimensional gel electrophoresis: an approach to understanding venom proteomics.
Proteomics 2005;5(2):501-10.
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2004: Lee Jae K; Laudeman Tom; Kanter Jodi; James Teela; Siadaty Mir S; Knaus William A; Prorok Alyson; Bao Yongde; Freeman Brad; Puiu Daniela; Wen Li Min; Buck Gregory A; Schlauch Karen; Weller Jennifer; Fox Jay W
GeneX Va: VBC open source microarray database and analysis software.
BioTechniques 2004;36(4):634-8, 640, 642.
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2003: Watanabe Leandra; Shannon John D; Valente Richard H; Rucavado Alexandra; Alape-Girón Alberto; Kamiguti Aura S; Theakston R David G; Fox Jay W; Gutiérrez José María; Arni Raghuvir K
Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities.
Protein science : a publication of the Protein Society 2003;12(10):2273-81.
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2003: Loría Gilbert D; Rucavado Alexandra; Kamiguti Aura S; Theakston R David G; Fox Jay W; Alape Alberto; Gutiérrez José María
Characterization of 'basparin A,' a prothrombin-activating metalloproteinase, from the venom of the snake Bothrops asper that inhibits platelet aggregation and induces defibrination and thrombosis.
Archives of biochemistry and biophysics 2003;418(1):13-24.
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2003: Kamiguti Aura S; Gallagher Paul; Marcinkiewicz Cezary; Theakston R David G; Zuzel Mirko; Fox Jay W
Identification of sites in the cysteine-rich domain of the class P-III snake venom metalloproteinases responsible for inhibition of platelet function.
FEBS letters 2003;549(1-3):129-34.
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2003: Gallagher Paul G; Bao Yongde; Serrano Solange M T; Kamiguti Aura S; Theakston R David G; Fox Jay W
Use of microarrays for investigating the subtoxic effects of snake venoms: insights into venom-induced apoptosis in human umbilical vein endothelial cells.
Toxicon : official journal of the International Society on Toxinology 2003;41(4):429-40.
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2003: Moura-da-Silva A M; Della-Casa M S; David A S; Assakura M T; Butera D; Lebrun I; Shannon J D; Serrano S M T; Fox J W
Evidence for heterogeneous forms of the snake venom metalloproteinase jararhagin: a factor contributing to snake venom variability.
Archives of biochemistry and biophysics 2003;409(2):395-401.
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2002: Zigrino Paola; Kamiguti Aura S; Eble Johannes; Drescher Claudia; Nischt Roswitha; Fox Jay W; Mauch Cornelia
The reprolysin jararhagin, a snake venom metalloproteinase, functions as a fibrillar collagen agonist involved in fibroblast cell adhesion and signaling.
The Journal of biological chemistry 2002;277(43):40528-35.
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2002: Luo An-Ming; Fox Jay W; Chen Lanlin; Bolton W Kline
Synthetic peptides of Goodpasture's antigen in antiglomerular basement membrane nephritis in rats.
The Journal of laboratory and clinical medicine 2002;139(5):303-10.
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2002: Neves-Ferreira Ana G C; Perales Jonas; Fox Jay W; Shannon John D; Makino Débora L; Garratt Richard C; Domont Gilberto B
Structural and functional analyses of DM43, a snake venom metalloproteinase inhibitor from Didelphis marsupialis serum.
The Journal of biological chemistry 2002;277(15):13129-37.
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2001: Sundell I B; Theakston R D; Kamiguti A S; Harris R J; Treweeke A T; Laing G D; Fox J W; Warrell D A; Zuzel M
The inhibition of platelet aggregation and blood coagulation by Micropechis ikaheka venom.
British journal of haematology 2001;114(4):852-60.
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2001: Valente R H; Dragulev B; Perales J; Fox J W; Domont G B
BJ46a, a snake venom metalloproteinase inhibitor. Isolation, characterization, cloning and insights into its mechanism of action.
European journal of biochemistry / FEBS 2001;268(10):3042-52.
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2001: Rucavado A; Soto M; Kamiguti A S; Theakston R D; Fox J W; Escalante T; Gutiérrez J M
Characterization of aspercetin, a platelet aggregating component from the venom of the snake Bothrops asper which induces thrombocytopenia and potentiates metalloproteinase-induced hemorrhage.
Thrombosis and haemostasis 2001;85(4):710-5.
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2000: Kamiguti A S; Theakston R D; Sherman N; Fox J W
Mass spectrophotometric evidence for P-III/P-IV metalloproteinases in the venom of the Boomslang (Dispholidus typus).
Toxicon : official journal of the International Society on Toxinology 2000;38(11):1613-20.
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2000: Lizano S; Angulo Y; Lomonte B; Fox J W; Lambeau G; Lazdunski M; Gutiérrez J M
Two phospholipase A2 inhibitors from the plasma of Cerrophidion (Bothrops) godmani which selectively inhibit two different group-II phospholipase A2 myotoxins from its own venom: isolation, molecular cloning and biological properties.
The Biochemical journal 2000;346 Pt 3():631-9.
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2000: Jia L G; Wang X M; Shannon J D; Bjarnason J B; Fox J W
Inhibition of platelet aggregation by the recombinant cysteine-rich domain of the hemorrhagic snake venom metalloproteinase, atrolysin A.
Archives of biochemistry and biophysics 2000;373(1):281-6.
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1998: Shimokawa K; Jia L G; Shannon J D; Fox J W
Isolation, sequence analysis, and biological activity of atrolysin E/D, the non-RGD disintegrin domain from Crotalus atrox venom.
Archives of biochemistry and biophysics 1998;354(2):239-46.
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1997: Lizano S; Lomonte B; Fox J W; Gutiérrez J M
Biochemical characterization and pharmacological properties of a phospholipase A2 myotoxin inhibitor from the plasma of the snake Bothrops asper.
The Biochemical journal 1997;326 ( Pt 3)():853-9.
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1997: Shimokawa K; Shannon J D; Jia L G; Fox J W
Sequence and biological activity of catrocollastatin-C: a disintegrin-like/cysteine-rich two-domain protein from Crotalus atrox venom.
Archives of biochemistry and biophysics 1997;343(1):35-43.
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1997: Jia L G; Wang X M; Shannon J D; Bjarnason J B; Fox J W
Function of disintegrin-like/cysteine-rich domains of atrolysin A. Inhibition of platelet aggregation by recombinant protein and peptide antagonists.
The Journal of biological chemistry 1997;272(20):13094-102.
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1996: Jia L G; Shimokawa K; Bjarnason J B; Fox J W
Snake venom metalloproteinases: structure, function and relationship to the ADAMs family of proteins.
Toxicon : official journal of the International Society on Toxinology 1996;34(11-12):1269-76.
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1996: Shimokawa K; Jia L G; Wang X M; Fox J W
Expression, activation, and processing of the recombinant snake venom metalloproteinase, pro-atrolysin E.
Archives of biochemistry and biophysics 1996;335(2):283-94.
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1995: Arruda L K; Vailes L D; Mann B J; Shannon J; Fox J W; Vedvick T S; Hayden M L; Chapman M D
Molecular cloning of a major cockroach (Blattella germanica) allergen, Bla g 2. Sequence homology to the aspartic proteases.
The Journal of biological chemistry 1995;270(33):19563-8.
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1995: Kristjánsson M M; Guthmundsdóttir S; Fox J W; Bjarnason J B
Characterization of a collagenolytic serine proteinase from the Atlantic cod (Gadus morhua).
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1995;110(4):707-17.
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1995: Fox J W; Bjarnason J B
Atrolysins: metalloproteinases from Crotalus atrox venom.
Methods in enzymology 1995;248():368-87.
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1995: Bjarnason J B; Fox J W
Snake venom metalloendopeptidases: reprolysins.
Methods in enzymology 1995;248():345-68.
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1994: Schaller M D; Hildebrand J D; Shannon J D; Fox J W; Vines R R; Parsons J T
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.
Molecular and cellular biology 1994;14(3):1680-8.
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1994: Hite L A; Jia L G; Bjarnason J B; Fox J W
cDNA sequences for four snake venom metalloproteinases: structure, classification, and their relationship to mammalian reproductive proteins.
Archives of biochemistry and biophysics 1994;308(1):182-91.
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1994: Bjarnason J B; Fox J W
Hemorrhagic metalloproteinases from snake venoms.
Pharmacology & therapeutics 1994;62(3):325-72.
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1992: Hite L A; Fox J W; Bjarnason J B
A new family of proteinases is defined by several snake venom metalloproteinases.
Biological chemistry Hoppe-Seyler 1992;373(7):381-5.
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1992: Hite L A; Shannon J D; Bjarnason J B; Fox J W
Sequence of a cDNA clone encoding the zinc metalloproteinase hemorrhagic toxin e from Crotalus atrox: evidence for signal, zymogen, and disintegrin-like structures.
Biochemistry 1992;31(27):6203-11.
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1991: Robeva A; Politi V; Shannon J D; Bjarnason J B; Fox J W
Synthetic and endogenous inhibitors of snake venom metalloproteinases.
Biomedica biochimica acta 1991;50(4-6):769-73.
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1991: Baramova E N; Shannon J D; Fox J W; Bjarnason J B
Proteolytic digestion of non-collagenous basement membrane proteins by the hemorrhagic metalloproteinase Ht-e from Crotalus atrox venom.
Biomedica biochimica acta 1991;50(4-6):763-8.
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1990: Arruda L K; Platts-Mills T A; Fox J W; Chapman M D
Aspergillus fumigatus allergen I, a major IgE-binding protein, is a member of the mitogillin family of cytotoxins.
The Journal of experimental medicine 1990;172(5):1529-32.
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1990: Baramova E N; Shannon J D; Bjarnason J B; Fox J W
Identification of the cleavage sites by a hemorrhagic metalloproteinase in type IV collagen.
Matrix (Stuttgart, Germany) 1990;10(2):91-7.
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1990: Lombardero M; Heymann P W; Platts-Mills T A; Fox J W; Chapman M D
Conformational stability of B cell epitopes on group I and group II Dermatophagoides spp. allergens. Effect of thermal and chemical denaturation on the binding of murine IgG and human IgE antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(4):1353-60.
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1990: Baramova E N; Shannon J D; Bjarnason J B; Gonias S L; Fox J W
Interaction of hemorrhagic metalloproteinases with human alpha 2-macroglobulin.
Biochemistry 1990;29(4):1069-74.
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1989: Baramova E N; Shannon J D; Bjarnason J B; Fox J W
Degradation of extracellular matrix proteins by hemorrhagic metalloproteinases.
Archives of biochemistry and biophysics 1989;275(1):63-71.
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1989: Lamas L; Anderson P C; Fox J W; Dunn J T
Consensus sequences for early iodination and hormonogenesis in human thyroglobulin.
The Journal of biological chemistry 1989;264(23):13541-5.
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1989: Shannon J D; Baramova E N; Bjarnason J B; Fox J W
Amino acid sequence of a Crotalus atrox venom metalloproteinase which cleaves type IV collagen and gelatin.
The Journal of biological chemistry 1989;264(20):11575-83.
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1989: Heymann P W; Chapman M D; Aalberse R C; Fox J W; Platts-Mills T A
Antigenic and structural analysis of group II allergens (Der f II and Der p II) from house dust mites (Dermatophagoides spp).
The Journal of allergy and clinical immunology 1989;83(6):1055-67.
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1989: Kupke D W; Fox J W
Volume changes in the binding of lanthanides to peptide analogues of loop II of calmodulin.
Biochemistry 1989;28(10):4409-15.
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1989: Asgeirsson B; Fox J W; Bjarnason J B
Purification and characterization of trypsin from the poikilotherm Gadus morhua.
European journal of biochemistry / FEBS 1989;180(1):85-94.
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1988: Fassler C A; Dunn J T; Anderson P C; Fox J W; Dunn A D; Hite L A; Moore R C; Kim P S
Thyrotropin alters the utilization of thyroglobulin's hormonogenic sites.
The Journal of biological chemistry 1988;263(33):17366-71.
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1988: Bjarnason J B; Hamilton D; Fox J W
Studies on the mechanism of hemorrhage production by five proteolytic hemorrhagic toxins from Crotalus atrox venom.
Biological chemistry Hoppe-Seyler 1988;369 Suppl():121-9.
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1987: Dunn J T; Anderson P C; Fox J W; Fassler C A; Dunn A D; Hite L A; Moore R C
The sites of thyroid hormone formation in rabbit thyroglobulin.
The Journal of biological chemistry 1987;262(35):16948-52.
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1987: Bjarnason J B; Fox J W
Characterization of two hemorrhagic zinc proteinases, toxin c and toxin d, from western diamondback rattlesnake (Crotalus atrox) venom.
Biochimica et biophysica acta 1987;911(3):356-63.
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1986: Fox J W; Campbell R; Beggerly L; Bjarnason J B
Substrate specificities and inhibition of two hemorrhagic zinc proteases Ht-c and Ht-d from Crotalus atrox venom.
European journal of biochemistry / FEBS 1986;156(1):65-72.
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1983: Bjarnason J B; Barish A; Direnzo G S; Campbell R; Fox J W
Kallikrein-like enzymes from Crotalus atrox venom.
The Journal of biological chemistry 1983;258(20):12566-73.
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1983: Bjarnason J B; Fox J W
Proteolytic specificity and cobalt exchange of hemorrhagic toxin e, a zinc protease isolated from the venom of the western diamondback rattlesnake (Crotalus atrox).
Biochemistry 1983;22(16):3770-8.
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