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Keith Fox

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David A Rusling; Iris S Nandhakumar; Tom Brown; Keith R Fox
Triplex-directed covalent cross-linking of a DNA nanostructure.
David A Rusling; Iris S Nandhakumar; Tom Brown; Keith R Fox
Triplex-directed recognition of a DNA nanostructure assembled by crossover strand exchange.
Antonia S Cardew; Tom Brown; Keith R Fox
Secondary binding sites for heavily modified triplex forming oligonucleotides.

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All Publications

2012: David A Rusling; Iris S Nandhakumar; Tom Brown; Keith R Fox
Triplex-directed covalent cross-linking of a DNA nanostructure.
Chemical communications (Cambridge, England) 2012;48(77):9592-4.
2012: David A Rusling; Iris S Nandhakumar; Tom Brown; Keith R Fox
Triplex-directed recognition of a DNA nanostructure assembled by crossover strand exchange.
ACS nano 2012;6(4):3604-13.
2012: Antonia S Cardew; Tom Brown; Keith R Fox
Secondary binding sites for heavily modified triplex forming oligonucleotides.
Nucleic acids research 2012;40(8):3753-62.
2011: Keith R Fox; Tom Brown
Formation of stable DNA triplexes.
Biochemical Society transactions 2011;39(2):629-34.
2010: Simon R Gerrard; Mastoura M Edrees; Imenne Bouamaied; Keith R Fox; Tom Brown
CG base pair recognition within DNA triple helices by modified N-methylpyrrolo-dC nucleosides.
Organic & biomolecular chemistry 2010;8(22):5087-96.
2010: Chenguang Lou; Qiang Xiao; Lavinia Brennan; Mark E Light; Nuria Vergara-Irigaray; Elizabeth M Atkinson; Lindy M Holden-Dye; Keith R Fox; Tom Brown
Synthesis and properties of triplex-forming oligonucleotides containing 2'-O-(2-methoxyethyl)-5-(3-aminoprop-1-ynyl)-uridine.
Bioorganic & medicinal chemistry 2010;18(17):6389-97.
2010: Antonia S Cardew; Keith R Fox
DNase I footprinting.
Methods in molecular biology (Clifton, N.J.) 2010;613():153-72.
2009: David A Rusling; Phillip A Rachwal; Tom Brown; Keith R Fox
The stability of triplex DNA is affected by the stability of the underlying duplex.
Biophysical chemistry 2009;145(2-3):105-10.
2009: Nouha Ben Gaied; Zhengyun Zhao; Simon R Gerrard; Keith R Fox; Tom Brown
Potent triple helix stabilization by 5',3'-modified triplex-forming oligonucleotides.
Chembiochem : a European journal of chemical biology 2009;10(11):1839-51.
2009: David A Rusling; Guomei Peng; Natarajan Srinivasan; Keith R Fox; Tom Brown
DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine.
Nucleic acids research 2009;37(4):1288-96.
2008: Andrew J Hampshire; David A Rusling; Stephanie Bryan; David Paumier; Simon J Dawson; John P Malkinson; Mark Searcey; Keith R Fox
DNA binding by analogues of the bifunctional intercalator TANDEM.
Biochemistry 2008;47(30):7900-6.
2008: Andrew J Hampshire; Keith R Fox
The effects of local DNA sequence on the interaction of ligands with their preferred binding sites.
Biochimie 2008;90(7):988-98.
2008: Andrew J Hampshire; Keith R Fox
Preferred binding sites for the bifunctional intercalator TANDEM determined using DNA fragments that contain every symmetrical hexanucleotide sequence.
Analytical biochemistry 2008;374(2):298-303.
2008: David A Rusling; Victoria J Broughton-Head; Alex Tuck; Hannah Khairallah; Sadie D Osborne; Tom Brown; Keith R Fox
Kinetic studies on the formation of DNA triplexes containing the nucleoside analogue 2'-O-(2-aminoethyl)-5-(3-amino-1-propynyl)uridine.
Organic & biomolecular chemistry 2008;6(1):122-9.
2007: Phillip A Rachwal; Keith R Fox
Quadruplex melting.
Methods (San Diego, Calif.) 2007;43(4):291-301.
2007: Andrew J Hampshire; David A Rusling; Victoria J Broughton-Head; Keith R Fox
Footprinting: a method for determining the sequence selectivity, affinity and kinetics of DNA-binding ligands.
Methods (San Diego, Calif.) 2007;42(2):128-40.
2007: Phillip A Rachwal; Tom Brown; Keith R Fox
Sequence effects of single base loops in intramolecular quadruplex DNA.
FEBS letters 2007;581(8):1657-60.
2007: Phillip A Rachwal; Tom Brown; Keith R Fox
Effect of G-tract length on the topology and stability of intramolecular DNA quadruplexes.
Biochemistry 2007;46(11):3036-44.
2007: Simon R Gerrard; Natarajan Srinivasan; Keith R Fox; Tom Brown
CG base pair recognition within DNA triple helices using N-methyl-3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one nucleoside analogues.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1363-7.
2007: Lavinia Brennan; Guomei Peng; Natarajan Srinivasan; Keith R Fox; Tom Brown
2'-o-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1283-6.
2007: Hong Li; Victoria J Broughton-Head; Keith R Fox; Tom Brown
Photoinduced crosslinking of double-helical DNA by psoralen covalently linked to a triple helix-forming oligonucleotide under near-physiological conditions.
Nucleosides, nucleotides & nucleic acids 2007;26(8-9):1005-9.
2007: Zhengyun Zhao; Guomei Peng; Jan Michels; Keith R Fox; Tom Brown
Synthesis of anthraquinone oligonucleotides for triplex stabilization.
Nucleosides, nucleotides & nucleic acids 2007;26(8-9):921-5.
2007: Phillip A Rachwal; I Stuart Findlow; Joern Werner; Tom Brown; Keith R Fox
Intramolecular DNA quadruplexes with different arrangements of short and long loops.
Nucleic acids research 2007;35(12):4214-22.
2006: Hong Li; Victoria J Broughton-Head; Guomei Peng; Vicki E C Powers; Matthew J Ovens; Keith R Fox; Tom Brown
Triplex staples: DNA double-strand cross-linking at internal and terminal sites using psoralen-containing triplex-forming oligonucleotides.
Bioconjugate chemistry 2006;17(6):1561-7.
2006: David A Rusling; Tom Brown; Keith R Fox
DNA triple-helix formation at target sites containing duplex mismatches.
Biophysical chemistry 2006;123(2-3):134-40.
2006: Joan Casals; Laurent Debéthune; Karine Alvarez; Antonina Risitano; Keith R Fox; Anna Grandas; Enrique Pedroso
Directing quadruplex-stabilizing drugs to the telomere: synthesis and properties of acridine-oligonucleotide conjugates.
Bioconjugate chemistry 2006;17(5):1351-9.
2006: Ceasar Christina; Richard Johnsson; Ulf Ellervik; Keith R Fox; Per Lincoln; Bengt Nordén
A polarized-light spectroscopy study of interactions of a hairpin polyamide with DNA.
Biophysical journal 2006;91(3):904-11.
2006: Andrew J Hampshire; Hannah Khairallah; Abedawn I Khalaf; Abdolrasoul Haghir Ebrahimabadi; Roger D Waigh; Colin J Suckling; Tom Brown; Keith R Fox
DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B).
Bioorganic & medicinal chemistry letters 2006;16(13):3469-74.
2006: James W Anderson; Keith R Fox; Graham A Niblo
A fast algorithm for the construction of universal footprinting templates in DNA.
Journal of mathematical biology 2006;52(3):307-42.
2005: David A Rusling; Loic Le Strat; Vicki E C Powers; Victoria J Broughton-Head; James Booth; Oliver Lack; Tom Brown; Keith R Fox
Combining nucleoside analogues to achieve recognition of oligopurine tracts by triplex-forming oligonucleotides at physiological pH.
FEBS letters 2005;579(29):6616-20.
2005: Nicholas M Brown; Phillip A Rachwal; Tom Brown; Keith R Fox
Exceptionally slow kinetics of the intramolecular quadruplex formed by the Oxytricha telomeric repeat.
Organic & biomolecular chemistry 2005;3(22):4153-7.
2005: Keith R Fox; Tom Brown
An extra dimension in nucleic acid sequence recognition.
Quarterly reviews of biophysics 2005;38(4):311-20.
2005: Elena E Merkina; Keith R Fox
Kinetic stability of intermolecular DNA quadruplexes.
Biophysical journal 2005;89(1):365-73.
2005: Rohan T Ranasinghe; David A Rusling; Vicki E C Powers; Keith R Fox; Tom Brown
Recognition of CG inversions in DNA triple helices by methylated 3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one nucleoside analogues.
Chemical communications (Cambridge, England) 2005;(20):2555-7.
2005: Yang Wang; David A Rusling; Vicki E C Powers; Oliver Lack; Sadie D Osborne; Keith R Fox; Tom Brown
Stable recognition of TA interruptions by triplex forming oligonucleotides containing a novel nucleoside.
Biochemistry 2005;44(15):5884-92.
2005: Antonina Risitano; Keith R Fox
Inosine substitutions demonstrate that intramolecular DNA quadruplexes adopt different conformations in the presence of sodium and potassium.
Bioorganic & medicinal chemistry letters 2005;15(8):2047-50.
2005: David A Rusling; Vicki E C Powers; Rohan T Ranasinghe; Yang Wang; Sadie D Osborne; Tom Brown; Keith R Fox
Four base recognition by triplex-forming oligonucleotides at physiological pH.
Nucleic acids research 2005;33(9):3025-32.
2004: Peter L James; Loic Le Strat; Ulf Ellervik; Christina Bratwall; Bengt Nordén; Tom Brown; Keith R Fox
Effects of a hairpin polyamide on DNA melting: comparison with distamycin and Hoechst 33258.
Biophysical chemistry 2004;111(3):205-12.
2004: Keith R Fox; Richard Webster; Robin J Phelps; Izabela Fokt; Waldemar Priebe
Sequence selective binding of bis-daunorubicin WP631 to DNA.
European journal of biochemistry / FEBS 2004;271(17):3556-66.
2004: Nahoum Anthony; Keith R Fox; Blair Johnston; Abedawn I Khalaf; Simon P Mackay; Iain S McGroarty; John A Parkinson; Graham G Skellern; Colin J Suckling; Roger D Waigh
DNA binding of a short lexitropsin.
Bioorganic & medicinal chemistry letters 2004;14(5):1353-6.
2004: Sadie D Osborne; Vicki E C Powers; David A Rusling; Oliver Lack; Keith R Fox; Tom Brown
Selectivity and affinity of triplex-forming oligonucleotides containing 2'-aminoethoxy-5-(3-aminoprop-1-ynyl)uridine for recognizing AT base pairs in duplex DNA.
Nucleic acids research 2004;32(15):4439-47.
2004: Peter L James; Elena E Merkina; Abedawn I Khalaf; Colin J Suckling; Roger D Waigh; Tom Brown; Keith R Fox
DNA sequence recognition by an isopropyl substituted thiazole polyamide.
Nucleic acids research 2004;32(11):3410-7.
2004: Antonina Risitano; Keith R Fox
Influence of loop size on the stability of intramolecular DNA quadruplexes.
Nucleic acids research 2004;32(8):2598-606.
2003: Melanie D Keppler; Peter L James; Stephen Neidle; Tom Brown; Keith R Fox
DNA sequence specificity of triplex-binding ligands.
European journal of biochemistry / FEBS 2003;270(24):4982-92.
2003: Peter L James; Tom Brown; Keith R Fox
Thermodynamic and kinetic stability of intermolecular triple helices containing different proportions of C+*GC and T*AT triplets.
Nucleic acids research 2003;31(19):5598-606.
2003: Antonina Risitano; Keith R Fox
The stability of intramolecular DNA quadruplexes with extended loops forming inter- and intra-loop duplexes.
Organic & biomolecular chemistry 2003;1(11):1852-5.
2003: Antonina Risitano; Keith R Fox
Stability of intramolecular DNA quadruplexes: comparison with DNA duplexes.
Biochemistry 2003;42(21):6507-13.
2003: James Brown; Tom Brown; Keith R Fox
Cleavage of fragments containing DNA mismatches by enzymic and chemical probes.
The Biochemical journal 2003;371(Pt 3):697-708.
2002: Matthieu Sollogoub; Richard A J Darby; Bernard Cuenoud; Tom Brown; Keith R Fox
Stable DNA triple helix formation using oligonucleotides containing 2'-aminoethoxy,5-propargylamino-U.
Biochemistry 2002;41(23):7224-31.
2002: Richard A J Darby; Matthieu Sollogoub; Catherine M McKeen; Lynda Brown; Antonina Risitano; Nicholas Brown; Christopher Barton; Tom Brown; Keith R Fox
High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler.
Nucleic acids research 2002;30(9):e39.
2002: Kris D Leslie; Keith R Fox
Interaction of Hoechst 33258 and echinomycin with nucleosomal DNA fragments containing isolated ligand binding sites.
Biochemistry 2002;41(10):3484-97.
2001: M Lavesa; Keith R Fox
Preferred binding sites for [N-MeCYs(3), N-MeCys(7)]TANDEM determined using a universal footprinting substrate.
Analytical biochemistry 2001;293(2):246-50.
2001: Melanie D Keppler; Stephen Neidle; Keith R Fox
Stabilisation of TG- and AG-containing antiparallel DNA triplexes by triplex-binding ligands.
Nucleic acids research 2001;29(9):1935-42.
2001: J Brown; Tom Brown; Keith R Fox
Affinity of mismatch-binding protein MutS for heteroduplexes containing different mismatches.
The Biochemical journal 2001;354(Pt 3):627-33.
2000: R V Fishleigh; Keith R Fox; Abedawn I Khalaf; Andrew Pitt; M Scobie; Colin J Suckling; J Urwin; Roger D Waigh; S C Young
DNA binding, solubility, and partitioning characteristics of extended lexitropsins.
Journal of medicinal chemistry 2000;43(17):3257-66.
2000: Keith R Fox; S L Allinson; H Sahagun-Krause; Tom Brown
Recognition of GT mismatches by Vsr mismatch endonuclease.
Nucleic acids research 2000;28(13):2535-40.
2000: Keith R Fox; E Flashman; DM Gowers
Secondary binding sites for triplex-forming oligonucleotides containing bulges, loops, and mismatches in the third strand.
Biochemistry 2000;39(22):6714-25.
1999: Melanie D Keppler; Catherine M McKeen; Oliwia Zegrocka; Lucjan Strekowski; Tom Brown; Keith R Fox
DNA triple helix stabilisation by covalent attachment of a triplex-specific ligand.
Biochimica et biophysica acta 1999;1447(2-3):137-45.
1999: DM Gowers; J Bijapur; Tom Brown; Keith R Fox
DNA triple helix formation at target sites containing several pyrimidine interruptions: stabilization by protonated cytosine or 5-(1-propargylamino)dU.
Biochemistry 1999;38(41):13747-58.
1999: Melanie D Keppler; Martin A Read; PJ Perry; John O Trent; TC Jenkins; Anthony P Reszka; Stephen Neidle; Keith R Fox
Stabilization of DNA triple helices by a series of mono- and disubstituted amidoanthraquinones.
European journal of biochemistry / FEBS 1999;263(3):817-25.
1999: Keith R Fox; Y Yan; B Gong
DNA sequence recognition by a novel series of minor groove-binding ligands.
Anti-cancer drug design 1999;14(3):219-30.
1999: J Bijapur; Melanie D Keppler; S Bergqvist; Tom Brown; Keith R Fox
5-(1-propargylamino)-2'-deoxyuridine (UP): a novel thymidine analogue for generating DNA triplexes with increased stability.
Nucleic acids research 1999;27(8):1802-9.
1999: PM Brown; Keith R Fox
DNA triple-helix formation on nucleosome core particles. Effect of length of the oligopurine tract.
European journal of biochemistry / FEBS 1999;261(1):301-10.
1999: DM Gowers; Keith R Fox
Towards mixed sequence recognition by triple helix formation.
Nucleic acids research 1999;27(7):1569-77.
1999: Melanie D Keppler; Oliwia Zegrocka; Lucjan Strekowski; Keith R Fox
DNA triple helix stabilisation by a naphthylquinoline dimer.
FEBS letters 1999;447(2-3):223-6.
1998: PM Brown; C A Madden; Keith R Fox
Triple-helix formation at different positions on nucleosomal DNA.
Biochemistry 1998;37(46):16139-51.
1998: DM Gowers; Keith R Fox
Triple helix formation at (AT)n adjacent to an oligopurine tract.
Nucleic acids research 1998;26(16):3626-33.
1998: PM Brown; Keith R Fox
DNA triple-helix formation on nucleosome-bound poly(dA).poly(dT) tracts.
The Biochemical journal 1998;333 ( Pt 2)():259-67.
1997: A Abu-Daya; Keith R Fox
Interaction of minor groove binding ligands with long AT tracts.
Nucleic acids research 1997;25(24):4962-9.
1997: S A Cassidy; P Slickers; John O Trent; D C Capaldi; P D Roselt; C B Reese; Stephen Neidle; Keith R Fox
Recognition of GC base pairs by triplex forming oligonucleotides containing nucleosides derived from 2-aminopyridine.
Nucleic acids research 1997;25(24):4891-8.
1997: Melanie D Keppler; Keith R Fox
Relative stability of triplexes containing different numbers of T.AT and C+.GC triplets.
Nucleic acids research 1997;25(22):4644-9.
1997: DM Gowers; Keith R Fox
DNA triple helix formation at oligopurine sites containing multiple contiguous pyrimidines.
Nucleic acids research 1997;25(19):3787-94.
1997: H M Paes; Keith R Fox
Kinetic studies on the formation of intermolecular triple helices.
Nucleic acids research 1997;25(16):3269-74.
1997: PM Brown; Keith R Fox
Footprinting studies with nucleosome-bound DNA.
Methods in molecular biology (Clifton, N.J.) 1997;90():81-93.
1997: Keith R Fox
DNase I footprinting.
Methods in molecular biology (Clifton, N.J.) 1997;90():1-22.
1996: S P Chandler; Keith R Fox
Specificity of antiparallel DNA triple helix formation.
Biochemistry 1996;35(47):15038-48.
1996: S A Cassidy; Lucjan Strekowski; Keith R Fox
DNA sequence specificity of a naphthylquinoline triple helix-binding ligand.
Nucleic acids research 1996;24(21):4133-8.
1996: PM Brown; Keith R Fox
Nucleosome core particles inhibit DNA triple helix formation.
The Biochemical journal 1996;319 ( Pt 2)():607-11.
1996: PM Brown; Keith R Fox
Minor groove binding ligands alter the rotational positioning of DNA fragments on nucleosome core particles.
Journal of molecular biology 1996;262(5):671-85.
1996: Keith R Fox; D E Thurston; TC Jenkins; Athanasia Varvaresou; A Tsotinis; T Siatra-Papastaikoudi
A novel series of DNA triple helix-binding ligands.
Biochemical and biophysical research communications 1996;224(3):717-20.
1996: M C Fletcher; Keith R Fox
Dissociation kinetics of actinomycin D from individual GpC sites in DNA.
European journal of biochemistry / FEBS 1996;237(1):164-70.
1996: PM Brown; A Drabble; Keith R Fox
Effect of a triplex-binding ligand on triple helix formation at a site within a natural DNA fragment.
The Biochemical journal 1996;314 ( Pt 2)():427-32.
1996: M C Fletcher; Keith R Fox
Visualising the dissociation of sequence selective ligands from individual binding sites on DNA.
FEBS letters 1996;380(1-2):118-22.
1996: M C Fletcher; Keith R Fox
Dissociation kinetics of echinomycin from CpG binding sites in different sequence environments.
Biochemistry 1996;35(3):1064-75.
1995: A Abu-Daya; PM Brown; Keith R Fox
DNA sequence preferences of several AT-selective minor groove binding ligands.
Nucleic acids research 1995;23(17):3385-92.
1995: S P Chandler; Lucjan Strekowski; David W. Wilson; Keith R Fox
Footprinting studies on ligands which stabilize DNA triplexes: effects on stringency within a parallel triple helix.
Biochemistry 1995;34(21):7234-42.
1995: S P Chandler; Keith R Fox
Extension of DNA triple helix formation to a neighbouring (AT)n site.
FEBS letters 1995;360(1):21-5.
1995: M C Fletcher; R K Olsen; Keith R Fox
Dissociation of the AT-specific bifunctional intercalator [N-MeCys3,N-MeCys7]TANDEM from TpA sites in DNA.
The Biochemical journal 1995;306 ( Pt 1)():15-9.
1995: Keith R Fox
Kinetic studies on the formation of acridine-linked DNA triple helices.
FEBS letters 1995;357(3):312-6.
1994: S A Cassidy; Lucjan Strekowski; David W. Wilson; Keith R Fox
Effect of a triplex-binding ligand on parallel and antiparallel DNA triple helices using short unmodified and acridine-linked oligonucleotides.
Biochemistry 1994;33(51):15338-47.
1994: E Washbrook; Keith R Fox
Comparison of antiparallel A.AT and T.AT triplets within an alternate strand DNA triple helix.
Nucleic acids research 1994;22(19):3977-82.
1994: M L Carpenter; S A Cassidy; Keith R Fox
Interaction of mithramycin with isolated GC and CG sites.
Journal of molecular recognition : JMR 1994;7(3):189-97.
1994: T J Stonehouse; Keith R Fox
DNase I footprinting of triple helix formation at polypurine tracts by acridine-linked oligopyrimidines: stringency, structural changes and interaction with minor groove binding ligands.
Biochimica et biophysica acta 1994;1218(3):322-30.
1994: E Washbrook; Keith R Fox
Alternate-strand DNA triple-helix formation using short acridine-linked oligonucleotides.
The Biochemical journal 1994;301 ( Pt 2)():569-75.
1994: Keith R Fox
Formation of DNA triple helices incorporating blocks of G.GC and T.AT triplets using short acridine-linked oligonucleotides.
Nucleic acids research 1994;22(11):2016-21.
1994: K P Nightingale; Keith R Fox
Light-activated cleavage of DNA by cobalt-bleomycin.
European journal of biochemistry / FEBS 1994;220(1):173-81.
1993: S P Chandler; Keith R Fox
Triple helix formation at A8XA8.T8YT8.
FEBS letters 1993;332(1-2):189-92.
1993: M L Carpenter; J N Marks; Keith R Fox
DNA-sequence binding preference of the GC-selective ligand mithramycin. Deoxyribonuclease-I/deoxyribonuclease-II and hydroxy-radical footprinting at CCCG, CCGC, CGGC, GCCC and GGGG flanked by (AT)n and An.Tn.
European journal of biochemistry / FEBS 1993;215(3):561-6.
1993: Keith R Fox; B M Cons
Interaction of mithramycin with DNA fragments complexed with nucleosome core particles: comparison with distamycin and echinomycin.
Biochemistry 1993;32(28):7162-71.
1993: K P Nightingale; Keith R Fox
DNA structure influences sequence specific cleavage by bleomycin.
Nucleic acids research 1993;21(11):2549-55.
1993: M C Fletcher; Keith R Fox
Visualising the kinetics of dissociation of actinomycin from individual sites in mixed sequence DNA by DNase I footprinting.
Nucleic acids research 1993;21(6):1339-44.
1993: M Lavesa; R K Olsen; Keith R Fox
Sequence-specific binding of [N-MeCys3,N-MeCys7]TANDEM to TpA.
The Biochemical journal 1993;289 ( Pt 2)():605-7.
1992: Keith R Fox
Probing the conformations of eight cloned DNA dodecamers; CGCGAATTCGCG, CGCGTTAACGCG, CGCGTATACGCG, CGCGATATCGCG, CGCAAATTTGCG, CGCTTTAAAGCG, CGCGGATCCGCG and CGCGGTACCGCG.
Nucleic acids research 1992;20(24):6487-93.
1992: Keith R Fox; Z Alam
Footprinting studies of DNA-sequence recognition by nogalamycin.
European journal of biochemistry / FEBS 1992;209(1):31-6.
1992: K Waterloh; Keith R Fox
Secondary (non-GpC) binding sites for actinomycin on DNA.
Biochimica et biophysica acta 1992;1131(3):300-6.
1992: K Waterloh; R K Olsen; Keith R Fox
Bifunctional intercalator [N-MeCys3,N-MeCys7]TANDEM binds to the dinucleotide TpA.
Biochemistry 1992;31(27):6246-53.
1992: K P Nightingale; Keith R Fox
Interaction of bleomycin with a bent DNA fragment.
The Biochemical journal 1992;284 ( Pt 3)():929-34.
1992: Keith R Fox
Wrapping of genomic polydA.polydT tracts around nucleosome core particles.
Nucleic acids research 1992;20(6):1235-42.
1992: Keith R Fox; S L Higson; J E Scott
Methyl green and its analogues bind selectively to AT-rich regions of native DNA.
European journal of histochemistry : EJH 1992;36(3):263-70.
1991: Keith R Fox; J N Marks; K Waterloh
Echinomycin binding to alternating AT.
Nucleic acids research 1991;19(24):6725-30.
1991: K Waterloh; Keith R Fox
Interaction of echinomycin with An.Tn. and (AT)n regions flanking its CG binding site.
Nucleic acids research 1991;19(24):6719-24.
1991: B M Cons; Keith R Fox
Effects of the antitumor antibiotic mithramycin on the structure of repetitive DNA regions adjacent to its GC-rich binding site.
Biochemistry 1991;30(25):6314-21.
1991: K Waterloh; Keith R Fox
The effects of actinomycin on the structure of dAn.dTn and (dA-dT)n regions surrounding its GC binding site. A footprinting study.
The Journal of biological chemistry 1991;266(10):6381-8.
1990: Keith R Fox
Footprinting studies of the interaction of quinomycin antibiotic UK63052 with DNA: comparison with echinomycin.
The Journal of antibiotics 1990;43(10):1307-15.
1990: B M Cons; Keith R Fox
Effects of sequence selective drugs on the gel mobility of a bent DNA fragment.
Biochemical and biophysical research communications 1990;171(3):1064-70.
1990: Keith R Fox
Long (dA)n.(dT)n tracts can form intramolecular triplexes under superhelical stress.
Nucleic acids research 1990;18(18):5387-91.
1990: Keith R Fox; E Kentebe
Footprinting studies on the effect of echinomycin on the structure of a bent DNA fragment.
The Biochemical journal 1990;269(1):217-21.
1990: Keith R Fox; C E Sansom; Malcolm F G Stevens
Footprinting studies on the sequence-selective binding of pentamidine to DNA.
FEBS letters 1990;266(1-2):150-4.
1990: B M Cons; Keith R Fox
The GC-selective ligand mithramycin alters the structure of (AT)n sequences flanking its binding sites.
FEBS letters 1990;264(1):100-4.
1990: Keith R Fox; E Kentebe
Echinomycin binding to the sequence CG(AT)nCG alters the structure of the central AT region.
Nucleic acids research 1990;18(8):1957-63.
1990: Keith R Fox; C Woolley
The strong binding of luzopeptin to DNA.
Biochemical pharmacology 1990;39(5):941-8.
1990: B M Cons; Keith R Fox
Footprinting studies of sequence recognition by mithramycin.
Anti-cancer drug design 1990;5(1):93-7.
1990: K Waterloh; Keith R Fox
Effect of actinomycin on a (TA)6 plasmid insert.
Anti-cancer drug design 1990;5(1):89-92.
1990: Keith R Fox
DNA sequence recognition by bleomycin.
Anti-cancer drug design 1990;5(1):99-104.
1989: B M Cons; Keith R Fox
High resolution hydroxyl radical footprinting of the binding of mithramycin and related antibiotics to DNA.
Nucleic acids research 1989;17(14):5447-59.
1989: Keith R Fox; S Kunimoto
Sequence selective binding of ditrisarubicin B to DNA: comparison with daunomycin.
FEBS letters 1989;250(2):323-7.
1989: B M Cons; Keith R Fox
Interaction of mithramycin with metal ions and DNA.
Biochemical and biophysical research communications 1989;160(2):517-24.
1988: Keith R Fox
Footprinting studies on the interactions of nogalamycin, arugomycin, decilorubicin and viriplanin with DNA.
Anti-cancer drug design 1988;3(3):157-68.
1988: Keith R Fox
DNAase I footprinting of restriction enzymes.
Biochemical and biophysical research communications 1988;155(2):779-85.
1988: Keith R Fox; G W Grigg
Diethylpyrocarbonate and permanganate provide evidence for an unusual DNA conformation induced by binding of the antitumour antibiotics bleomycin and phleomycin.
Nucleic acids research 1988;16(5):2063-75.