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Patricia Foxworthy

Research Profile

Anatomy

Chemicals & Drugs

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Oxidation-Reduction

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Rebecca R Miles; Marian K Mosior; Mathias N'Cho; William Perry; Timothy P Ryan; Patricia J Solenberg; Jian W J Wang; Peng Yu; Yong Yue; John Calley; Quincy Carter; Patricia Foxworthy; Joseph V Haas; Bomie Han; Mark C Kowala; Laura F Michael
Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretion.
Mark Rekhter; Kirk Staschke; Thomas B Estridge; Pamela Rutherford; Nancy Jackson; Donetta Gifford-Moore; Patricia Foxworthy; Charles Reidy; Xiao-di Huang; Michael Kalbfleisch; Kwan Hui; Ming-Shang Kuo; Raymond Gilmour; chris vlahos
Genetic ablation of IRAK4 kinase activity inhibits vascular lesion formation.
Tonghuan Hu; Patricia Foxworthy; Angela Siesky; James V Ficorilli; Hong Gao; Shuyu Li; Michael Christe; Timothy Ryan; Guoqing Cao; Patrick I Eacho; M Dodson Michael; Laura F Michael
Hepatic peroxisomal fatty acid beta-oxidation is regulated by liver X receptor alpha.

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All Publications

2013: Rebecca R Miles; Marian K Mosior; Mathias N'Cho; William Perry; Timothy P Ryan; Patricia J Solenberg; Jian W J Wang; Peng Yu; Yong Yue; John Calley; Quincy Carter; Patricia Foxworthy; Joseph V Haas; Bomie Han; Mark C Kowala; Laura F Michael
Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretion.
The Journal of biological chemistry 2013;288(9):6386-96.
2008: Mark Rekhter; Kirk Staschke; Thomas B Estridge; Pamela Rutherford; Nancy Jackson; Donetta Gifford-Moore; Patricia Foxworthy; Charles Reidy; Xiao-di Huang; Michael Kalbfleisch; Kwan Hui; Ming-Shang Kuo; Raymond Gilmour; chris vlahos
Genetic ablation of IRAK4 kinase activity inhibits vascular lesion formation.
Biochemical and biophysical research communications 2008;367(3):642-8.
2005: Tonghuan Hu; Patricia Foxworthy; Angela Siesky; James V Ficorilli; Hong Gao; Shuyu Li; Michael Christe; Timothy Ryan; Guoqing Cao; Patrick I Eacho; M Dodson Michael; Laura F Michael
Hepatic peroxisomal fatty acid beta-oxidation is regulated by liver X receptor alpha.
Endocrinology 2005;146(12):5380-7.
2005: Youyan Zhang; Robert J Schmidt; Patricia Foxworthy; Renee Emkey; Jennifer K Oler; Thomas H Large; He Wang; Eric W Su; Marion K Mosior; Patrick I Eacho; Guoqing Cao
Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A.
Biochemical and biophysical research communications 2005;334(2):729-32.
2004: Thomas P Beyer; Robert J Schmidt; Patricia Foxworthy; Youyan Zhang; Jiannong Dai; William R Bensch; Raymond F Kauffman; Hong Gao; Timothy P Ryan; Xian-Cheng Jiang; Sotirios Karathanasis; Patrick I Eacho; Guoqing Cao
Coadministration of a liver X receptor agonist and a peroxisome proliferator activator receptor-alpha agonist in Mice: effects of nuclear receptor interplay on high-density lipoprotein and triglyceride metabolism in vivo.
The Journal of pharmacology and experimental therapeutics 2004;309(3):861-8.
2003: Jeffrey Thomas; Kelli S Bramlett; Chahrzad Montrose; Patricia Foxworthy; Patrick I Eacho; Denis McCann; Guoqing Cao; Anton Kiefer; Jeff McCowan; Kuo-Long Yu; Timothy Grese; William W Chin; Burris thomas; Laura F Michael
A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (PPARalpha ) versus liver X receptor.
The Journal of biological chemistry 2003;278(4):2403-10.
2003: Guoqing Cao; Yu Liang; Carol L Broderick; Brian A Oldham; Thomas P Beyer; Robert J Schmidt; Youyan Zhang; Keith R Stayrook; Chen S Suen; Keith A Otto; Anne R Miller; Jiannong Dai; Patricia Foxworthy; Hong Gao; Timothy P Ryan; Xian-Cheng Jiang; Burris thomas; Patrick I Eacho; Garret J Etgen
Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.
The Journal of biological chemistry 2003;278(2):1131-6.
2002: Daniel R Jones; Robert J Schmidt; Richard T Pickard; Patricia Foxworthy; Patrick I Eacho
Estrogen receptor-mediated repression of human hepatic lipase gene transcription.
Journal of lipid research 2002;43(3):383-91.
1999: Ho-Shen Lin; AA Rampersaud; Lisa S Beavers; DB McClure; A J Gardner; Patrick I Eacho; Patricia Foxworthy; Robert A Gadski
Synthesis and in vitro biological activity of 4alpha-(2-propenyl)-5alpha-cholest-24-en-3alpha,12 alpha-diol, a 12alpha-hydroxyl analog of 4alpha-(2-propenyl)-5alpha-cholest-24-en-3alpha-ol: the latter is a potent activator of the low-density lipoprotein receptor promoter.
Steroids 1999;64(10):735-41.
1999: Ho-Shen Lin; AA Rampersaud; Michael E Richett; RW Harper; Lisa S Beavers; DB McClure; A J Gardner; Patrick I Eacho; Patricia Foxworthy; Robert A Gadski
Synthesis and in vitro biological activity of 4alpha-(2-propenyl)-5alpha-cholest-24-en-3alpha-ol: a 24,25-dehydro analog of the hypocholesterolemic agent 4alpha-(2-propenyl)-5alpha-cholestan-3alpha-ol.
Steroids 1999;64(3):217-27.
1996: Patrick I Eacho; Patricia Foxworthy; J W Lawrence; David K Herron; D J Noonan
Common structural requirements for peroxisome proliferation by tetrazole and carboxylic acid-containing compounds.
Annals of the New York Academy of Sciences 1996;804():387-402.
1995: J W Lawrence; Patricia Foxworthy; D N Perry; C B Jensen; D D Giera; V P Meador; Patrick I Eacho
Nafenopin-induced peroxisome proliferation in vitamin A deficient rats.
Biochemical pharmacology 1995;49(7):915-9.
1994: Patricia Foxworthy; Patrick I Eacho
Cultured hepatocytes for studies of peroxisome proliferation: methods and applications.
Journal of pharmacological and toxicological methods 1994;31(1):21-30.
1993: S L White; D A Laska; Patricia Foxworthy; J L Gimple; D M Hoover
Cell culture supports for slam-frozen and molecular distillation dried procedures.
Microscopy research and technique 1993;26(2):184-5.
1993: Patricia Foxworthy; D N Perry; Patrick I Eacho
Induction of peroxisomal beta-oxidation by nonsteroidal anti-inflammatory drugs.
Toxicology and applied pharmacology 1993;118(2):271-4.
1992: Patrick I Eacho; T L Lanier; Patricia Foxworthy; D M Hoover
Effect of the peroxisome proliferator LY171883 on hepatocellular replication in female B6C3F1 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1992;18(4):632-4.
1991: Patricia Foxworthy; Patrick I Eacho
Effect of the peroxisome proliferator LY171883 on triglyceride accumulation in rats fed a fat-free diet.
Biochemical pharmacology 1991;42(7):1487-91.
1990: Patricia Foxworthy; D N Perry; D M Hoover; Patrick I Eacho
Changes in hepatic lipid metabolism associated with lipid accumulation and its reversal in rats given the peroxisome proliferator LY171883.
Toxicology and applied pharmacology 1990;106(3):375-83.
1990: A M Bendele; D M Hoover; R B van Lier; Patricia Foxworthy; Patrick I Eacho
Effects of chronic treatment with the leukotriene D4-antagonist compound LY171883 on B6C3F1 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;15(4):676-82.
1990: Patricia Foxworthy; S L White; D M Hoover; Patrick I Eacho
Effect of ciprofibrate, bezafibrate, and LY171883 on peroxisomal beta-oxidation in cultured rat, dog, and rhesus monkey hepatocytes.
Toxicology and applied pharmacology 1990;104(3):386-94.
1990: D M Hoover; A M Bendele; W P Hoffman; Patricia Foxworthy; Patrick I Eacho
Effects of chronic treatment with the leukotriene D4 antagonist compound LY171883 on Fischer 344 rats and rhesus monkeys.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;14(1):123-30.
1989: Patrick I Eacho; Patricia Foxworthy; R D Dillard; CA Whitesitt; David K Herron; W S Marshall
Induction of peroxisomal beta-oxidation in the rat liver in vivo and in vitro by tetrazole-substituted acetophenones: structure-activity relationships.
Toxicology and applied pharmacology 1989;100(1):177-84.
1988: Patrick I Eacho; Patricia Foxworthy
Inhibition of hepatic fatty acid oxidation by bezafibrate and bezafibroyl CoA.
Biochemical and biophysical research communications 1988;157(3):1148-53.
1988: Patricia Foxworthy; Patrick I Eacho
Inhibition of hepatic fatty acid oxidation at carnitine palmitoyltransferase I by the peroxisome proliferator 2-hydroxy-3-propyl-4-[6-(tetrazol-5-yl) hexyloxy]acetophenone.
The Biochemical journal 1988;252(2):409-14.
1986: Patrick I Eacho; Patricia Foxworthy; W D Johnson; D M Hoover; S L White
Hepatic peroxisomal changes induced by a tetrazole-substituted alkoxyacetophenone in rats and comparison with other species.
Toxicology and applied pharmacology 1986;83(3):430-7.
1986: Patricia Foxworthy; Patrick I Eacho
Conditions influencing the induction of peroxisomal beta-oxidation in cultured rat hepatocytes.
Toxicology letters 1986;30(2):189-96.
1985: Patrick I Eacho; Patricia Foxworthy; W D Johnson; R B van Lier
Characterization of liver enlargement induced by compound LY171883 in rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1985;5(4):794-803.