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Daniela Fraccarollo

Research Profile

Living Beings

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Anatomy

Endothelium, Vascular

Physiology

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Publications

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Stefan Frantz; Ina Hagedorn; Ulrich Hofmann; Susanne Kneitz; Stefanie Kranepuhl; Matthias Nahrendorf; Bernhard Nieswandt; Christina Pachel; Andreas Schäfer; Michael P Schön; Helga Wagner; Frank Weidemann; Barbara Bayer; Tobias Bobinger; Georg Ertl; Daniela Fraccarollo; Johann Bauersachs
Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction.
Ulrike Flierl; Daniela Fraccarollo; Eva Lausenmeyer; Steffen Massberg; Tim Rosenstock; Johann Bauersachs; Christian Schulz; Andreas Schäfer
Fractalkine activates a signal transduction pathway similar to P2Y12 and is associated with impaired clopidogrel responsiveness.
Daniela Fraccarollo; Paolo Galuppo; Johann Bauersachs
Novel therapeutic approaches to post-infarction remodelling.

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All Publications

2013: Stefan Frantz; Ina Hagedorn; Ulrich Hofmann; Susanne Kneitz; Stefanie Kranepuhl; Matthias Nahrendorf; Bernhard Nieswandt; Christina Pachel; Andreas Schäfer; Michael P Schön; Helga Wagner; Frank Weidemann; Barbara Bayer; Tobias Bobinger; Georg Ertl; Daniela Fraccarollo; Johann Bauersachs
Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013;27(3):871-81.
2012: Ulrike Flierl; Daniela Fraccarollo; Eva Lausenmeyer; Steffen Massberg; Tim Rosenstock; Johann Bauersachs; Christian Schulz; Andreas Schäfer
Fractalkine activates a signal transduction pathway similar to P2Y12 and is associated with impaired clopidogrel responsiveness.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(8):1832-40.
2012: Daniela Fraccarollo; Paolo Galuppo; Johann Bauersachs
Novel therapeutic approaches to post-infarction remodelling.
Cardiovascular research 2012;94(2):293-303.
2011: Andreas Schäfer; Daniela Fraccarollo; Stephanie Pförtsch; Elena Loch; Jonas Neuser; Christian Vogt; Johann Bauersachs
Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure.
Basic research in cardiology 2011;106(3):485-94.
2011: Daniela Fraccarollo; Johann Bauersachs
Cardiomyocyte mineralocorticoid receptor function post myocardial infarction.
Trends in cardiovascular medicine 2011;21(2):42-7.
2011: Daniela Fraccarollo; Stefan Berger; Paolo Galuppo; Susanne Kneitz; Lutz Hein; Günther Schütz; Stefan Frantz; Georg Ertl; Johann Bauersachs
Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction.
Circulation 2011;123(4):400-8.
2010: Andreas Schäfer; Daniela Fraccarollo; Lennart Werner; Johann Bauersachs
Guanylyl cyclase activator ataciguat improves vascular function and reduces platelet activation in heart failure.
Pharmacological research : the official journal of the Italian Pharmacological Society 2010;62(5):432-8.
2010: Natalie Burkard; Tatjana Williams; Martin Czolbe; Nadja Blömer; Franziska Panther; Martin Link; Daniela Fraccarollo; Julian Widder; Kai Hu; Hong Han; Ulrich Hofmann; Stefan Frantz; Peter Nordbeck; Jan Bulla; Kai Schuh; Oliver Ritter
Conditional overexpression of neuronal nitric oxide synthase is cardioprotective in ischemia/reperfusion.
Circulation 2010;122(16):1588-603.
2010: Andreas Schäfer; Paolo Galuppo; Daniela Fraccarollo; Christian Vogt; Julian D Widder; Julia Pfrang; Piet Tas; Eduardo Barbosa-Sicard; Hartmut Ruetten; Georg Ertl; Ingrid Fleming; Johann Bauersachs
Increased cytochrome P4502E1 expression and altered hydroxyeicosatetraenoic acid formation mediate diabetic vascular dysfunction: rescue by guanylyl-cyclase activation.
Diabetes 2010;59(8):2001-9.
2009: Julian Widder; Daniela Fraccarollo; Paolo Galuppo; Jason M Hansen; Dean P Jones; Georg Ertl; Johann Bauersachs
Attenuation of angiotensin II-induced vascular dysfunction and hypertension by overexpression of Thioredoxin 2.
Hypertension 2009;54(2):338-44.
2009: Andreas Schäfer; Daniela Fraccarollo; Julian Widder; Martin Eigenthaler; Georg Ertl; Johann Bauersachs
Inhibition of platelet activation in rats with severe congestive heart failure by a novel endothelial nitric oxide synthase transcription enhancer.
European journal of heart failure 2009;11(4):336-41.
2008: Daniela Fraccarollo; Julian Widder; Paolo Galuppo; Thomas Thum; Dimitrios Tsikas; Michael Hoffmann; Hartmut Ruetten; Georg Ertl; Johann Bauersachs
Improvement in left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction.
Circulation 2008;118(8):818-27.
2008: Jörn Tongers; Julia-Marie Knapp; Mortimer Korf; Tibor Kempf; Anne Limbourg; Florian P Limbourg; Zhixiong Li; Daniela Fraccarollo; Johann Bauersachs; Xiaoqiang Han; Helmut Drexler; Beate Fiedler; Kai C Wollert
Haeme oxygenase promotes progenitor cell mobilization, neovascularization, and functional recovery after critical hindlimb ischaemia in mice.
Cardiovascular research 2008;78(2):294-300.
2008: Daniela Fraccarollo; Paolo Galuppo; Susanne Schraut; Susanne Kneitz; Nico van Rooijen; Georg Ertl; Johann Bauersachs
Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response.
Hypertension 2008;51(4):905-14.
2008: Johann Bauersachs; Daniela Fraccarollo
More NO-no more ROS: combined selective mineralocorticoid receptor blockade and angiotensin-converting enzyme inhibition for vascular protection.
Hypertension 2008;51(3):624-5.
2008: Andreas Schäfer; Daniela Fraccarollo; S Pförtsch; Ulrike Flierl; C Vogt; J Pfrang; Anna Kobsar; T Renné; Martin Eigenthaler; Georg Ertl; Johann Bauersachs
Improvement of vascular function by acute and chronic treatment with the PDE-5 inhibitor sildenafil in experimental diabetes mellitus.
British journal of pharmacology 2008;153(5):886-93.
2007: Carmem Luiza Sartorio; Daniela Fraccarollo; Paolo Galuppo; Meike Leutke; Georg Ertl; Ivanita Stefanon; Johann Bauersachs
Mineralocorticoid receptor blockade improves vasomotor dysfunction and vascular oxidative stress early after myocardial infarction.
Hypertension 2007;50(5):919-25.
2007: Andreas Schäfer; Daniela Fraccarollo; Christian Vogt; Ulrike Flierl; Melinda Hemberger; Piet Tas; Georg Ertl; Johann Bauersachs
Improved endothelial function and reduced platelet activation by chronic HMG-CoA-reductase inhibition with rosuvastatin in rats with streptozotocin-induced diabetes mellitus.
Biochemical pharmacology 2007;73(9):1367-75.
2007: Thomas Thum; Daniela Fraccarollo; Sabrina Thum; Maximilian Schultheiss; Andreas Daiber; Philip Wenzel; Thomas Munzel; Georg Ertl; Johann Bauersachs
Differential effects of organic nitrates on endothelial progenitor cells are determined by oxidative stress.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):748-54.
2007: Thomas Thum; Daniela Fraccarollo; Maximilian Schultheiss; Sabrina Froese; Paolo Galuppo; Julian Widder; Dimitrios Tsikas; Georg Ertl; Johann Bauersachs
Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes.
Diabetes 2007;56(3):666-74.
2007: Stefan Frantz; T Behr; Kai Hu; Daniela Fraccarollo; Jörg Strotmann; E Goldberg; Georg Ertl; Christiane E Angermann; Johann Bauersachs
Role of p38 mitogen-activated protein kinase in cardiac remodelling.
British journal of pharmacology 2007;150(2):130-5.
2007: Andreas Schäfer; Christian Schulz; Daniela Fraccarollo; Piet Tas; Meike Leutke; Martin Eigenthaler; Stefan Seidl; Peter Heider; Georg Ertl; Steffen Massberg; Johann Bauersachs
The CX3C chemokine fractalkine induces vascular dysfunction by generation of superoxide anions.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(1):55-62.
2006: Johann Bauersachs; Katrin Hiss; Daniela Fraccarollo; Ulrich Laufs; Hartmut Ruetten
Simvastatin improves left ventricular function after myocardial infarction in hypercholesterolemic rabbits by anti-inflammatory effects.
Cardiovascular research 2006;72(3):438-46.
2006: Johann Bauersachs; Daniela Fraccarollo
Endothelial NO synthase target of aldosterone.
Hypertension 2006;48(1):27-8.
2006: Thomas Thum; Daniela Fraccarollo; Paolo Galuppo; Dimitrios Tsikas; Stefan Frantz; Georg Ertl; Johann Bauersachs
Bone marrow molecular alterations after myocardial infarction: Impact on endothelial progenitor cells.
Cardiovascular research 2006;70(1):50-60.
2005: Daniela Fraccarollo; Paolo Galuppo; Isabel Schmidt; Georg Ertl; Johann Bauersachs
Additive amelioration of left ventricular remodeling and molecular alterations by combined aldosterone and angiotensin receptor blockade after myocardial infarction.
Cardiovascular research 2005;67(1):97-105.
2005: Andreas Schäfer; Daniela Fraccarollo; Martin Eigenthaler; Piet Tas; Andreas Firnschild; Stefan Frantz; Georg Ertl; Johann Bauersachs
Rosuvastatin reduces platelet activation in heart failure: role of NO bioavailability.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(5):1071-7.
2004: Daniela Fraccarollo; Paolo Galuppo; Johann Bauersachs
Mineralocorticoid receptor antagonism and cardiac remodeling in ischemic heart failure.
Current medicinal chemistry. Cardiovascular and hematological agents 2004;2(4):287-94.
2004: Julian Widder; Thomas Behr; Daniela Fraccarollo; Kai Hu; Paolo Galuppo; Piet Tas; Christiane E Angermann; Georg Ertl; Johann Bauersachs
Vascular endothelial dysfunction and superoxide anion production in heart failure are p38 MAP kinase-dependent.
Cardiovascular research 2004;63(1):161-7.
2004: Kai Hu; Anne Naumann; Daniela Fraccarollo; Peter Gaudron; Jens J Kaden; Stefan Neubauer; Georg Ertl
Heart rate reduction by zatebradine reduces infarct size and mortality but promotes remodeling in rats with experimental myocardial infarction.
American journal of physiology. Heart and circulatory physiology 2004;286(4):H1281-8.
2004: Andreas Schäfer; Daniela Fraccarollo; Piet Tas; Isabel Schmidt; Georg Ertl; Johann Bauersachs
Endothelial dysfunction in congestive heart failure: ACE inhibition vs. angiotensin II antagonism.
European journal of heart failure 2004;6(2):151-9.
2004: Andreas Schäfer; Christian Schulz; Martin Eigenthaler; Daniela Fraccarollo; Anna Kobsar; Meinrad Gawaz; Georg Ertl; Ulrich Walter; Johann Bauersachs
Novel role of the membrane-bound chemokine fractalkine in platelet activation and adhesion.
Blood 2004;103(2):407-12.
2003: Daniela Fraccarollo; Paolo Galuppo; Steven K Hildemann; Michael Christ; Georg Ertl; Johann Bauersachs
Additive improvement of left ventricular remodeling and neurohormonal activation by aldosterone receptor blockade with eplerenone and ACE inhibition in rats with myocardial infarction.
Journal of the American College of Cardiology 2003;42(9):1666-73.
2003: Andreas Schäfer; Daniela Fraccarollo; Steven K Hildemann; Piet Tas; Georg Ertl; Johann Bauersachs
Addition of the selective aldosterone receptor antagonist eplerenone to ACE inhibition in heart failure: effect on endothelial dysfunction.
Cardiovascular research 2003;58(3):655-62.
2003: Andreas Schäfer; Daniela Fraccarollo; Steven K Hildemann; Michael Christ; Martin Eigenthaler; Anna Kobsar; Ulrich Walter; Johann Bauersachs
Inhibition of platelet activation in congestive heart failure by aldosterone receptor antagonism and ACE inhibition.
Thrombosis and haemostasis 2003;89(6):1024-30.
2003: Johann Bauersachs; Daniela Fraccarollo
Aldosterone antagonism in addition to angiotensin-converting enzyme inhibitors in heart failure.
Minerva cardioangiologica 2003;51(2):155-64.
2003: Stefan Frantz; Daniela Fraccarollo; Helga Wagner; Thomas M Behr; Philip Jung; Christiane E Angermann; Georg Ertl; Johann Bauersachs
Sustained activation of nuclear factor kappa B and activator protein 1 in chronic heart failure.
Cardiovascular research 2003;57(3):749-56.
2003: Matthias Nahrendorf; Kai Hu; Daniela Fraccarollo; Karl-Heinz Hiller; Axel Haase; Wolfgang R Bauer; Georg Ertl
Time course of right ventricular remodeling in rats with experimental myocardial infarction.
American journal of physiology. Heart and circulatory physiology 2003;284(1):H241-8.
2002: Jörg Strotmann; Johann Bauersachs; Daniela Fraccarollo; Michael Kirchengast; Philipp A Schnabel; Jaromir Sykora; Georg Ertl; Wolfram Voelker
Trauma induced by nontraumatic coronary devices and its impact on vascular reactivity and morphology.
American journal of physiology. Heart and circulatory physiology 2002;283(6):H2356-62.
2002: Matthias Nahrendorf; Kai Hu; Karl-Heinz Hiller; Paolo Galuppo; Daniela Fraccarollo; German Schweizer; Axel Haase; Georg Ertl; Wolfgang R Bauer; Johann Bauersachs
Impact of hydroxymethylglutaryl coenzyme a reductase inhibition on left ventricular remodeling after myocardial infarction: an experimental serial cardiac magnetic resonance imaging study.
Journal of the American College of Cardiology 2002;40(9):1695-700.
2002: Johann Bauersachs; Daniela Fraccarollo; Andreas Schäfer; Georg Ertl
Angiotensin-converting enzyme inhibition and endothelin antagonism for endothelial dysfunction in heart failure: mono-or combination therapy.
Journal of cardiovascular pharmacology 2002;40(4):594-600.
2002: Daniela Fraccarollo; Paolo Galuppo; Johann Bauersachs; Georg Ertl
Collagen accumulation after myocardial infarction: effects of ETA receptor blockade and implications for early remodeling.
Cardiovascular research 2002;54(3):559-67.
2002: Daniela Fraccarollo; Johann Bauersachs; Markus Kellner; Paolo Galuppo; Georg Ertl
Cardioprotection by long-term ET(A) receptor blockade and ACE inhibition in rats with congestive heart failure: mono- versus combination therapy.
Cardiovascular research 2002;54(1):85-94.
2002: Johann Bauersachs; Marina Heck; Daniela Fraccarollo; Steven K Hildemann; Georg Ertl; Martin Wehling; Michael Christ
Addition of spironolactone to angiotensin-converting enzyme inhibition in heart failure improves endothelial vasomotor dysfunction: role of vascular superoxide anion formation and endothelial nitric oxide synthase expression.
Journal of the American College of Cardiology 2002;39(2):351-8.
2001: Johann Bauersachs; Paolo Galuppo; Daniela Fraccarollo; Michael Christ; Georg Ertl
Improvement of left ventricular remodeling and function by hydroxymethylglutaryl coenzyme a reductase inhibition with cerivastatin in rats with heart failure after myocardial infarction.
Circulation 2001;104(9):982-5.
2001: Johann Bauersachs; Ingrid Fleming; Daniela Fraccarollo; Rudi Busse; Georg Ertl
Prevention of endothelial dysfunction in heart failure by vitamin E: attenuation of vascular superoxide anion formation and increase in soluble guanylyl cyclase expression.
Cardiovascular research 2001;51(2):344-50.
2000: Johann Bauersachs; Claude Braun; Daniela Fraccarollo; Julian Widder; Georg Ertl; Lothar Schilling; Michael Kirchengast; Peter Rohmeiss
Improvement of renal dysfunction in rats with chronic heart failure after myocardial infarction by treatment with the endothelin A receptor antagonist, LU 135252.
Journal of hypertension 2000;18(10):1507-14.
2000: Peter Gaudron; L Kugler; Kai Hu; Daniela Fraccarollo; W Bauer; C Eilles; Georg Ertl
Effect of quinapril initiated during progressive remodeling in asymptomatic patients with healed myocardial infarction.
The American journal of cardiology 2000;86(2):139-44.
2000: Johann Bauersachs; Daniela Fraccarollo; Paolo Galuppo; Julian Widder; Georg Ertl
Endothelin-receptor blockade improves endothelial vasomotor dysfunction in heart failure.
Cardiovascular research 2000;47(1):142-9.
2000: Julian Widder; Johann Bauersachs; Daniela Fraccarollo; Georg Ertl; Lothar Schilling
Endothelium-dependent and -independent vasoreactivity of rat basilar artery in chronic heart failure.
Journal of cardiovascular pharmacology 2000;35(4):515-22.
1999: Johann Bauersachs; Anne Bouloumié; Daniela Fraccarollo; K Hu; Rudi Busse; Georg Ertl
Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: role of enhanced vascular superoxide production.
Circulation 1999;100(3):292-8.
1998: Johann Bauersachs; Anne Bouloumié; Daniela Fraccarollo; K Hu; Rudi Busse; Georg Ertl
Hydralazine prevents endothelial dysfunction, but not the increase in superoxide production in nitric oxide-deficient hypertension.
European journal of pharmacology 1998;362(1):77-81.
1998: Georg Ertl; Daniela Fraccarollo; Peter Gaudron; Kai Hu; A Laser; Stefan Neubauer; W Schorb
[Transition of myocardial ischemia to heart failure].
Zeitschrift für Kardiologie 1998;87(9):667-75.
1997: Daniela Fraccarollo; Kai Hu; Paolo Galuppo; Peter Gaudron; Georg Ertl
Chronic endothelin receptor blockade attenuates progressive ventricular dilation and improves cardiac function in rats with myocardial infarction: possible involvement of myocardial endothelin system in ventricular remodeling.
Circulation 1997;96(11):3963-73.