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Raymond Frade

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Chemicals & Drugs

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Human Herpesvirus 4

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Alice Barbarin; Raymond Frade
Procathepsin L secretion, which triggers tumour progression, is regulated by Rab4a in human melanoma cells.
Didier Jean; Nathalie Rousselet; Raymond Frade
Cathepsin L expression is up-regulated by hypoxia in human melanoma cells: role of its 5'-untranslated region.
Séverine Lottin-Divoux; Didier Jean; Muriel Le Romancer; Raymond Frade
Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav.

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All Publications

2011: Alice Barbarin; Raymond Frade
Procathepsin L secretion, which triggers tumour progression, is regulated by Rab4a in human melanoma cells.
The Biochemical journal 2011;437(1):97-107.
2008: Didier Jean; Nathalie Rousselet; Raymond Frade
Cathepsin L expression is up-regulated by hypoxia in human melanoma cells: role of its 5'-untranslated region.
The Biochemical journal 2008;413(1):125-34.
2006: Séverine Lottin-Divoux; Didier Jean; Muriel Le Romancer; Raymond Frade
Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav.
Cellular signalling 2006;18(8):1219-25.
2006: Didier Jean; N Rousselet; Raymond Frade
Expression of cathepsin L in human tumor cells is under the control of distinct regulatory mechanisms.
Oncogene 2006;25(10):1474-84.
2005: Michelle Balbo; Monique Barel; Séverine Lottin-Divoux; Didier Jean; Raymond Frade
Infection of human B lymphoma cells by Mycoplasma fermentans induces interaction of its elongation factor with the intracytoplasmic domain of Epstein-Barr virus receptor (gp140, EBV/C3dR, CR2, CD21).
FEMS microbiology letters 2005;249(2):359-66.
2005: Séverine Lottin-Divoux; Monique Barel; Raymond Frade
RB18A enhances expression of mutant p53 protein in human cells.
FEBS letters 2005;579(11):2323-6.
2004: Nathalie Rousselet; Lisa D. Mills; Didier Jean; Carmen Tellez; Menashe Bar-Eli; Raymond Frade
Inhibition of tumorigenicity and metastasis of human melanoma cells by anti-cathepsin L single chain variable fragment.
Cancer research 2004;64(1):146-51.
2003: Monique Barel; Michelle Balbo; Muriel Le Romancer; Raymond Frade
Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human cell surface triggers pp60src and Akt-GSK3 activities upstream and downstream to PI 3-kinase, respectively.
European journal of immunology 2003;33(9):2557-66.
2002: Nathalie Guillaume-Rousselet; Didier Jean; Raymond Frade
Cloning and characterization of anti-cathepsin L single chain variable fragment whose expression inhibits procathepsin L secretion in human melanoma cells.
The Biochemical journal 2002;367(Pt 1):219-27.
2002: Raymond Frade; Michelle Balbo; Monique Barel
RB18A regulates p53-dependent apoptosis.
Oncogene 2002;21(6):861-6.
2002: Didier Jean; Nathalie Guillaume; Raymond Frade
Characterization of human cathepsin L promoter and identification of binding sites for NF-Y, Sp1 and Sp3 that are essential for its activity.
The Biochemical journal 2002;361(Pt 1):173-84.
2001: Monique Barel; Muriel Le Romancer; Raymond Frade
Activation of the EBV/C3d receptor (CR2, CD21) on human B lymphocyte surface triggers tyrosine phosphorylation of the 95-kDa nucleolin and its interaction with phosphatidylinositol 3 kinase.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3167-73.
2000: Raymond Frade; Michelle Balbo; Monique Barel
RB18A, whose gene is localized on chromosome 17q12-q21.1, regulates in vivo p53 transactivating activity.
Cancer research 2000;60(23):6585-9.
1999: Raymond Frade
Structure and functions of proteases which cleave human C3 and are expressed on normal or tumor human cells: some are involved in tumorigenic and metastatic properties of human melanoma cells.
Immunopharmacology 1999;42(1-3):39-45.
1999: S Bouillie; Monique Barel; Raymond Frade
Signaling through the EBV/C3d receptor (CR2, CD21) in human B lymphocytes: activation of phosphatidylinositol 3-kinase via a CD19-independent pathway.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(1):136-43.
1998: Monique Barel; Michelle Balbo; Raymond Frade
Evidence for a new transcript of the Epstein-Barr virus/C3d receptor (CR2, CD21) which is due to alternative exon usage.
Molecular immunology 1998;35(16):1025-31.
1998: Raymond Frade; Fernando Rodrigues-Lima; Suyun Huang; Keping Xie; N Guillaume; Menashe Bar-Eli
Procathepsin-L, a proteinase that cleaves human C3 (the third component of complement), confers high tumorigenic and metastatic properties to human melanoma cells.
Cancer research 1998;58(13):2733-6.
1998: Fernando Rodrigues-Lima; J Hermann; Didier Jean; Raymond Frade
Alpha 1-proteinase inhibitor is the serum regulator of the activity of p57, a C3-cleaving proteinase present in human erythrocyte membranes.
Biochimica et biophysica acta 1998;1402(2):131-8.
1997: P Drané; Monique Barel; Michelle Balbo; Raymond Frade
Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53.
Oncogene 1997;15(25):3013-24.
1997: Didier Jean; Fernando Rodrigues-Lima; Bruno Cassinat; J Hermann; jean paul cabane; Raymond Frade
Co-expression and secretion of C3, the third component of complement and a C3-cleaving cysteine proteinase in a highly metastatic human melanoma cell line.
Immunology letters 1997;58(2):107-12.
1996: Didier Jean; Menashe Bar-Eli; Suyun Huang; Keping Xie; Fernando Rodrigues-Lima; J Hermann; Raymond Frade
A cysteine proteinase, which cleaves human C3, the third component of complement, is involved in tumorigenicity and metastasis of human melanoma.
Cancer research 1996;56(2):254-8.
1995: Didier Jean; J Hermann; Fernando Rodrigues-Lima; Monique Barel; Michelle Balbo; Raymond Frade
Identification on melanoma cells of p39, a cysteine proteinase that cleaves C3, the third component of complement: amino-acid-sequence identities with procathepsin L.
The Biochemical journal 1995;312 ( Pt 3)():961-9.
1995: Michelle Balbo; Monique Barel; S Bouillie; P Drane; B Cassinat; Raymond Frade
Pep34, a synthetic peptide whose sequence corresponds to the intracytoplasmic domain of the Epstein-Barr virus receptor (CR2, CD21), regulates human B lymphocyte proliferation triggered through CR2.
Molecular immunology 1995;32(16):1295-8.
1995: S Bouillie; Monique Barel; P Drane; B Cassinat; Michelle Balbo; V M Holers; Raymond Frade
Epstein-Barr virus/C3d receptor (CR2, CD21) activated by its extracellular ligands regulates pp105 phosphorylation through two distinct pathways.
European journal of immunology 1995;25(9):2661-7.
1995: Monique Barel; Michelle Balbo; A Gauffre; Raymond Frade
Binding sites of the Epstein-Barr virus and C3d receptor (CR2, CD21) for its three intracellular ligands, the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein.
Molecular immunology 1995;32(6):389-97.
1994: J Hermann; Monique Barel; Raymond Frade
Human erythrocyte ankyrin, a cytoskeleton component, generates the p57 membrane proteinase which cleaves C3, the third component of complement.
Biochemical and biophysical research communications 1994;204(2):453-60.
1993: A Kahan; E Collantes-Estevez; Monique Barel; Raymond Frade; Bernard Amor
Expression of complement receptors (CR1 and CR3) and Fc gamma RIII on polymorphonuclears from patients with spondylarthropathies.
Clinical and experimental rheumatology 1993;11(1):27-34.
1992: Raymond Frade; A Gauffre; J Hermann; Monique Barel
EBV/C3d receptor (CR2) interacts by its intracytoplasmic carboxy-terminal domain and two distinct binding sites with the p53 anti-oncoprotein and the p68 calcium-binding protein.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(10):3232-8.
1992: Raymond Frade; J Hermann; Monique Barel
A 16 amino acid synthetic peptide derived from human C3d triggers proliferation and specific tyrosine phosphorylation of transformed CR2-positive human lymphocytes and of normal resting B lymphocytes.
Biochemical and biophysical research communications 1992;188(2):833-42.
1992: A Gauffre; A Viron; Monique Barel; J Hermann; Edmond Puvion; Raymond Frade
Nuclear localization of the Epstein-Barr virus/C3d receptor (CR2) in the human Burkitt B lymphoma cell, Raji.
Molecular immunology 1992;29(9):1113-20.
1991: Monique Barel; A Gauffre; F Lyamani; A Fiandino; J Hermann; Raymond Frade
Intracellular interaction of EBV/C3d receptor (CR2) with p68, a calcium-binding protein present in normal but not in transformed B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(4):1286-91.
1991: A Fiandino-Tirel; Monique Barel; F Lyamani; A Gauffre; J Hermann; Raymond Frade
Characterization of a monoclonal antibody against P57, the C3/C3b-cleaving proteinase expressed in human erythrocyte membranes.
Hybridoma 1991;10(4):449-58.
1991: F Lyamani; A Gauffre; Monique Barel; A Fiandino-Tirel; J Hermann; Raymond Frade
A 16 amino-acid synthetic peptide, derived from human C3d, carries regulatory activity on in vitro phosphorylation of a cellular component of the human B lymphoma cells, Raji.
Biochemical and biophysical research communications 1991;175(3):823-30.
1990: Markus Ollert; Raymond Frade; A Fiandino; M Panneerselvam; E C Petrella; Monique Barel; M K Pangburn; Reinhard Bredehorst; Carl-Wilhelm Vogel
C3-cleaving membrane proteinase. A new complement regulatory protein of human melanoma cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(10):3862-7.
1990: Raymond Frade
Structure and signalling functions of C3 receptors on human B cells.
Seminars in immunology 1990;2(2):159-64.
1989: Monique Barel; A Fiandino; F Lyamani; Raymond Frade
Epstein-Barr virus/complement fragment C3d receptor (CR2) reacts with p53, a cellular antioncogene-encoded membrane phosphoprotein: detection by polyclonal anti-idiotypic anti-CR2 antibodies.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):10054-8.
1989: A X Delcayre; A Fiandino; F Lyamani; Monique Barel; Raymond Frade
Enhancement of Epstein-Barr virus/C3d receptor (EBV/C3dR or CR2) and nuclear p120 ribonucleoprotein phosphorylation by specific EBV/C3dR ligands in subcellular fractions of the human B lymphoma cell line, Raji.
Biochemical and biophysical research communications 1989;159(3):1213-20.
1988: Monique Barel; A Fiandino; A X Delcayre; F Lyamani; Raymond Frade
Monoclonal and anti-idiotypic anti-EBV/C3d receptor antibodies detect two binding sites, one for EBV and one for C3d on glycoprotein 140, the EBV/C3dR, expressed on human B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(5):1590-5.
1987: A X Delcayre; A Fiandino; Monique Barel; Raymond Frade
gp140, the EBV/C3d receptor (CR2) of human B lymphocytes, is involved in cell-free phosphorylation of p120, a nuclear ribonucleoprotein.
European journal of immunology 1987;17(12):1827-33.
1987: Jacques A Hatzfeld; C Charriaut-Marlangue; J P Levesque; Monique Barel; R Stancou; L Krikorian; Antoinette Hatzfeld; Raymond Frade
[C3 stimulates the proliferation of human pre-B Raji cells].
Annales de l'Institut Pasteur. Immunology 1987;138(3):451-5.
1987: D Nunez; C Charriaut-Marlangue; Monique Barel; J Benveniste; Raymond Frade
Activation of human platelets through gp140, the C3d/EBV receptor (CR2).
European journal of immunology 1987;17(4):515-20.
1986: A Kahan; C Charriaut-Marlangue; A Kahan; Monique Barel; C J Menkes; B Amor; Raymond Frade
Increased expression of Epstein-Barr virus receptor on lymphoblastoid cell lines from subsets of patients with rheumatoid arthritis.
The Journal of rheumatology 1986;13(6):1024-7.
1986: C Charriaut-Marlangue; Monique Barel; Raymond Frade
Identification of P-57, a serine proteinase, from human erythrocyte membranes, which cleaves both chains of human third component (C3) of complement.
Biochemical and biophysical research communications 1986;140(3):1113-20.
1986: Monique Barel; A Kahan; C Charriaut-Marlangue; A Kahan; Raymond Frade
Autoantibodies against gp140, the Epstein-Barr virus and C3d receptor in sera from rheumatoid arthritis patients.
European journal of immunology 1986;16(11):1357-61.
1986: Monique Barel; A Vazquez; C Charriaut; M T Aufredou; P Galanaud; Raymond Frade
gp 140, the C3d/EBV receptor (CR2), is phosphorylated upon in vitro activation of human peripheral B lymphocytes.
FEBS letters 1986;197(1-2):353-6.
1985: Raymond Frade; B L Myones; Monique Barel; L Krikorian; C Charriaut; Gordon D Ross
gp140, a C3b-binding membrane component of lymphocytes, is the B cell C3dg/C3d receptor (CR2) and is distinct from the neutrophil C3dg receptor (CR4).
European journal of immunology 1985;15(12):1192-7.
1985: Raymond Frade; Monique Barel; B Ehlin-Henriksson; G Klein
gp140, the C3d receptor of human B lymphocytes, is also the Epstein-Barr virus receptor.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(5):1490-3.
1985: Raymond Frade; M C Crevon; Monique Barel; A Vazquez; L Krikorian; C Charriaut; P Galanaud
Enhancement of human B cell proliferation by an antibody to the C3d receptor, the gp 140 molecule.
European journal of immunology 1985;15(1):73-6.
1984: Raymond Frade; Monique Barel; L Krikorian; C Charriaut
Analysis of gp 140, a C3b-binding membrane component present on Raji cells: a comparison with factor H.
European journal of immunology 1984;14(6):542-8.
1983: Raymond Frade; Monique Barel; C Charriaut
Use of solid-phase radioimmunoassay specific for human IgG or human C3b to detect Fc gamma or C3b receptors on human lymphoblastoid cell surfaces.
Methods in enzymology 1983;93():155-63.
1983: Monique Barel; C Charriaut; Raymond Frade
A simple solid phase radioimmunoassay specific for human C3b to detect C3b receptors on human lymphoblastoid cell surfaces.
International archives of allergy and applied immunology 1983;71(1):1-5.
1982: C Charriaut; A Senik; J P Kolb; Monique Barel; Raymond Frade
Inhibition of in vitro natural killer activity by the third component of complement: role for the C3a fragment.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(19):6003-7.
1982: C Charriaut; Monique Barel; Raymond Frade
Behavior of soluble human 125I-labeled C3b, the third component of complement, after binding to human cells.
European journal of immunology 1982;12(4):289-94.
1981: Monique Barel; C Charriaut; Raymond Frade
Isolation and characterization of a C3b receptor-like molecule from membranes of a human B lymphoblastoid cell line (Raji).
FEBS letters 1981;136(1):111-4.
1981: Monique Barel; C Charriaut; Raymond Frade
Use of cell differentiation effectors to select a human B lymphoblastoid cell line enriched in C3b receptors.
Journal of immunological methods 1981;46(2):187-95.
1980: Monique Barel; Raymond Frade
Detection of Fc gamma receptors on human lymphoblastoid cell surfaces using a simple solid phase radioimmunoassay specific for human IgG.
Journal of immunological methods 1980;37(2):123-31.