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Guido Franceschini

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Monica Gomaraschi; Alice Ossoli; Cristina Pitzorno; Silvia Pozzi; Gianfranco Sinagra; Laura Vitali Serdoz; Cecilia Vitali; Guido Franceschini; Laura Calabresi
Off-target effects of thrombolytic drugs: apolipoprotein A-I proteolysis by alteplase and tenecteplase.
Laura Calabresi; Monica Gomaraschi; Sara Simonelli; Guido Franceschini
Genetic lecithin:cholesterol acyltransferase deficiency and cardiovascular disease.
Paola Conca; Guido Franceschini; Emanuela Boer; Giuliano Boscutti; Laura Calabresi; Lucia Magnolo; Silvana Penco; Silvana Pileggi; Sara Simonelli; Patrizia Tarugi; Monica Gomaraschi
Novel missense variants in LCAT and APOB genes in an Italian kindred with familial lecithin:cholesterol acyltransferase deficiency and hypobetalipoproteinemia.

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All Publications

2013: Monica Gomaraschi; Alice Ossoli; Cristina Pitzorno; Silvia Pozzi; Gianfranco Sinagra; Laura Vitali Serdoz; Cecilia Vitali; Guido Franceschini; Laura Calabresi
Off-target effects of thrombolytic drugs: apolipoprotein A-I proteolysis by alteplase and tenecteplase.
Biochemical pharmacology 2013;85(4):525-30.
2012: Laura Calabresi; Monica Gomaraschi; Sara Simonelli; Guido Franceschini
Genetic lecithin:cholesterol acyltransferase deficiency and cardiovascular disease.
Atherosclerosis 2012;222(2):299-306.
2012: Paola Conca; Guido Franceschini; Emanuela Boer; Giuliano Boscutti; Laura Calabresi; Lucia Magnolo; Silvana Penco; Silvana Pileggi; Sara Simonelli; Patrizia Tarugi; Monica Gomaraschi
Novel missense variants in LCAT and APOB genes in an Italian kindred with familial lecithin:cholesterol acyltransferase deficiency and hypobetalipoproteinemia.
Journal of clinical lipidology 2012;6(3):244-50.
2012: Livia Pisciotta; Raffaella Sallo; Sara Simonelli; Patrizia Tarugi; Ivana Zavaroni; Maria Pia Adorni; Diego Ardigò; Franco Bernini; Laura Calabresi; Sebastiano Calandra; Tatiana Fancello; Elda Favari; Guido Franceschini; Lucia Magnolo; Stefano Bertolini
Characterization of three kindreds with familial combined hypolipidemia caused by loss-of-function mutations of ANGPTL3.
Circulation. Cardiovascular genetics 2012;5(1):42-50.
2012: Sara Simonelli; Cesare R Sirtori; alessandra fraccari; Giovanni Ferraro; Guido Franceschini; Elisabetta Gianazza; Giuliana Mombelli; Silvana Penco; Laura Calabresi
Severe high-density lipoprotein deficiency associated with autoantibodies against lecithin:cholesterol acyltransferase in non-Hodgkin lymphoma.
Archives of internal medicine 2012;172(2):179-81.
2011: Laura Calabresi; Samuela Castelnuovo; Ulf de Faire; Guido Franceschini; Beatrice Frigerio; Philippe Giral; Monica Gomaraschi; Anders Hamsten; Steve E Humphries; Jussi Kauhanen; Elmo Mannarino; Rainer Rauramaa; Alessio Ravani; Daniela Sansaro; Sara Simonelli; Cesare R Sirtori; Andries J Smit; Mauro Amato; Damiano Baldassarre; Fabrizio Veglia; Elena Tremoli
Plasma lecithin:cholesterol acyltransferase and carotid intima-media thickness in European individuals at high cardiovascular risk.
Journal of lipid research 2011;52(8):1569-74.
2011: Monica Gomaraschi; Laura Obici; Sara Simonelli; Gina Gregorini; Alessandro Negrinelli; Giampaolo Merlini; Guido Franceschini; Laura Calabresi
Effect of the amyloidogenic L75P apolipoprotein A-I variant on HDL subpopulations.
Clinica chimica acta; international journal of clinical chemistry 2011;412(13-14):1262-5.
2010: Alessandro Guerini Rocco; Cristina Sensi; Elisabetta Gianazza; Laura Calabresi; Guido Franceschini; Cesare R Sirtori; Ivano Eberini
Structural and dynamic features of apolipoprotein A-I cysteine mutants, Milano and Paris, in synthetic HDL.
Journal of molecular graphics & modelling 2010;29(3):406-14.
2010: Laura Calabresi; Monica Gomaraschi; Guido Franceschini
High-density lipoprotein quantity or quality for cardiovascular prevention?
Current pharmaceutical design 2010;16(13):1494-503.
2010: Monica Gomaraschi; Wendy E Putt; Silvia Pozzi; Stefania Iametti; Alberto Barbiroli; Francesco Bonomi; Elda Favari; Franco Bernini; Guido Franceschini; Philippa J Talmud; Laura Calabresi
Structure and function of the apoA-IV T347S and Q360H common variants.
Biochemical and biophysical research communications 2010;393(1):126-30.
2010: Laura Calabresi; Guido Franceschini
Lecithin:cholesterol acyltransferase, high-density lipoproteins, and atheroprotection in humans.
Trends in cardiovascular medicine 2010;20(2):50-3.
2009: Elda Favari; Laura Calabresi; Maria Pia Adorni; Wendy Jessup; Sara Simonelli; Guido Franceschini; Franco Bernini
Small discoidal pre-beta1 HDL particles are efficient acceptors of cell cholesterol via ABCA1 and ABCG1.
Biochemistry 2009;48(46):11067-74.
2009: Alessandro Guerini Rocco; Elisabetta Gianazza; Laura Calabresi; Cristina Sensi; Guido Franceschini; Cesare R Sirtori; Ivano Eberini
Structural features and dynamics properties of human apolipoprotein A-I in a model of synthetic HDL.
Journal of molecular graphics & modelling 2009;28(4):305-12.
2009: Laura Calabresi; Damiano Baldassarre; Samuela Castelnuovo; Paola Conca; Letizia Bocchi; Chiara Candini; Beatrice Frigerio; Mauro Amato; Cesare R Sirtori; paola alessandrini; Marcello Arca; Giuliano Boscutti; Luigi Cattin; Loreto Gesualdo; Tiziana Sampietro; Gaetano Vaudo; Fabrizio Veglia; Sebastiano Calandra; Guido Franceschini
Functional lecithin: cholesterol acyltransferase is not required for efficient atheroprotection in humans.
Circulation 2009;120(7):628-35.
2009: Laura Calabresi; Peter Nilsson; Elisa Pinotti; Monica Gomaraschi; Elda Favari; Maria Pia Adorni; Franco Bernini; Cesare R Sirtori; Sebastiano Calandra; Guido Franceschini; Patrizia Tarugi
A novel homozygous mutation in CETP gene as a cause of CETP deficiency in a Caucasian kindred.
Atherosclerosis 2009;205(2):506-11.
2009: Laura Calabresi; Elda Favari; Elsa Moleri; Maria Pia Adorni; Matteo Pedrelli; Sara Costa; Wendy Jessup; Ingrid C Gelissen; Petri T Kovanen; Franco Bernini; Guido Franceschini
Functional LCAT is not required for macrophage cholesterol efflux to human serum.
Atherosclerosis 2009;204(1):141-6.
2008: Paola Conca; Guido Franceschini
Synthetic HDL as a new treatment for atherosclerosis regression: has the time come?
Nutrition, metabolism, and cardiovascular diseases : NMCD 2008;18(4):329-35.
2008: Ilaria Zanotti; Francesco Potì; Matteo Pedrelli; Elda Favari; Elsa Moleri; Guido Franceschini; Laura Calabresi; Franco Bernini
The LXR agonist T0901317 promotes the reverse cholesterol transport from macrophages by increasing plasma efflux potential.
Journal of lipid research 2008;49(5):954-60.
2008: Monica Gomaraschi; Laura Calabresi; Giuseppe Rossoni; Stefania Iametti; Guido Franceschini; John Anthony Stonik; Alan T Remaley
Anti-inflammatory and cardioprotective activities of synthetic high-density lipoprotein containing apolipoprotein A-I mimetic peptides.
The Journal of pharmacology and experimental therapeutics 2008;324(2):776-83.
2007: Guido Franceschini; Laura Calabresi; Cinzia Colombo; Elda Favari; Franco Bernini; Cesare R Sirtori
Effects of fenofibrate and simvastatin on HDL-related biomarkers in low-HDL patients.
Atherosclerosis 2007;195(2):385-91.
2007: Monica Gomaraschi; Damiano Baldassarre; Mauro Amato; Sonia Eligini; Paola Conca; Cesare R Sirtori; Guido Franceschini; Laura Calabresi
Normal vascular function despite low levels of high-density lipoprotein cholesterol in carriers of the apolipoprotein A-I(Milano) mutant.
Circulation 2007;116(19):2165-72.
2007: Elda Favari; Monica Gomaraschi; Ilaria Zanotti; Franco Bernini; Miriam Lee-Rueckert; Petri T Kovanen; Cesare R Sirtori; Guido Franceschini; Laura Calabresi
A unique protease-sensitive high density lipoprotein particle containing the apolipoprotein A-I(Milano) dimer effectively promotes ATP-binding Cassette A1-mediated cell cholesterol efflux.
The Journal of biological chemistry 2007;282(8):5125-32.
2006: Stefano Bellosta; Monica Gomaraschi; Monica Canavesi; Giuseppe Rossoni; Mara Monetti; Guido Franceschini; Laura Calabresi
Inhibition of MMP-2 activation and release as a novel mechanism for HDL-induced cardioprotection.
FEBS letters 2006;580(25):5974-8.
2006: Alessandro Guerini Rocco; Luca Mollica; Elisabetta Gianazza; Laura Calabresi; Guido Franceschini; Cesare R Sirtori; Ivano Eberini
A model structure for the heterodimer apoA-IMilano-apoA-II supports its peculiar susceptibility to proteolysis.
Biophysical journal 2006;91(8):3043-9.
2006: Monica Gomaraschi; Laura Calabresi; Guido Franceschini
High-density lipoproteins: a therapeutic target for atherosclerotic cardiovascular disease.
Expert opinion on therapeutic targets 2006;10(4):561-72.
2006: Cesare R Sirtori; Laura Calabresi; Damiano Baldassarre; Guido Franceschini; Angelo B Cefalù; Maurizio R Averna
CETP levels rather than polymorphisms as markers of coronary risk: healthy athlete with high HDL-C and coronary disease--effectiveness of probucol.
Atherosclerosis 2006;186(1):225-7.
2006: Laura Calabresi; Cesare R Sirtori; Rodolfo Paoletti; Guido Franceschini
Recombinant apolipoprotein A-IMilano for the treatment of cardiovascular diseases.
Current atherosclerosis reports 2006;8(2):163-7.
2005: Monica Gomaraschi; Nicoletta Basilico; Francesca Sisto; Donatella Taramelli; Sonia Eligini; Susanna Colli; Cesare R Sirtori; Guido Franceschini; Laura Calabresi
High-density lipoproteins attenuate interleukin-6 production in endothelial cells exposed to pro-inflammatory stimuli.
Biochimica et biophysica acta 2005;1736(2):136-43.
2005: Laura Calabresi; Livia Pisciotta; Anna Costantin; Ilaria Frigerio; Ivano Eberini; paola alessandrini; Marcello Arca; Gabriele Bittolo Bon; Giuliano Boscutti; Ghil Busnach; Giovanni M Frascà; Loreto Gesualdo; Maddalena Gigante; graziana lupattelli; Anna Montali; Stefano Pizzolitto; Ivana Rabbone; Marina Rolleri; Giacomo Ruotolo; Tiziana Sampietro; Adalberto Sessa; Gaetano Vaudo; Alfredo Cantafora; Fabrizio Veglia; Sebastiano Calandra; Stefano Bertolini; Guido Franceschini
The molecular basis of lecithin:cholesterol acyltransferase deficiency syndromes: a comprehensive study of molecular and biochemical findings in 13 unrelated Italian families.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(9):1972-8.
2004: Giovanni M Frascà; Letizia Soverini; Elena Tampieri; Guido Franceschini; Laura Calabresi; Livia Pisciotta; Paola Preda; Alba Vangelista; Sergio Stefoni; Stefano Bertolini
A 33-year-old man with nephrotic syndrome and lecithin-cholesterol acyltransferase (LCAT) deficiency. Description of two new mutations in the LCAT gene.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(6):1622-4.
2004: Elda Favari; Miriam Lee; Laura Calabresi; Guido Franceschini; Francesca Zimetti; Franco Bernini; Petri T Kovanen
Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1- but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein.
The Journal of biological chemistry 2004;279(11):9930-6.
2004: Laura Calabresi; Barbara Villa; Monica Canavesi; Cesare R Sirtori; Richard W James; Franco Bernini; Guido Franceschini
An omega-3 polyunsaturated fatty acid concentrate increases plasma high-density lipoprotein 2 cholesterol and paraoxonase levels in patients with familial combined hyperlipidemia.
Metabolism: clinical and experimental 2004;53(2):153-8.
2004: Giuseppe Rossoni; Monica Gomaraschi; Ferruccio Berti; Cesare R Sirtori; Guido Franceschini; Laura Calabresi
Synthetic high-density lipoproteins exert cardioprotective effects in myocardial ischemia/reperfusion injury.
The Journal of pharmacology and experimental therapeutics 2004;308(1):79-84.
2003: Laura Calabresi; Monica Gomaraschi; Guido Franceschini
Endothelial protection by high-density lipoproteins: from bench to bedside.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(10):1724-31.
2003: Livia Pisciotta; Roberto Miccoli; Alfredo Cantafora; Laura Calabresi; Patrizia Tarugi; paola alessandrini; Gabriele Bittolo Bon; Guido Franceschini; Claudio Cortese; Sebastiano Calandra; Stefano Bertolini
Recurrent mutations of the apolipoprotein A-I gene in three kindreds with severe HDL deficiency.
Atherosclerosis 2003;167(2):335-45.
2003: Miriam Lee; Petri T Kovanen; Gabriella Tedeschi; Emanuela Oungre; Guido Franceschini; Laura Calabresi
Apolipoprotein composition and particle size affect HDL degradation by chymase: effect on cellular cholesterol efflux.
Journal of lipid research 2003;44(3):539-46.
2003: Laura Calabresi; Giuseppe Rossoni; Monica Gomaraschi; Francesca Sisto; Ferruccio Berti; Guido Franceschini
High-density lipoproteins protect isolated rat hearts from ischemia-reperfusion injury by reducing cardiac tumor necrosis factor-alpha content and enhancing prostaglandin release.
Circulation research 2003;92(3):330-7.
2002: Elda Favari; Franco Bernini; Patrizia Tarugi; Guido Franceschini; Laura Calabresi
The C-terminal domain of apolipoprotein A-I is involved in ABCA1-driven phospholipid and cholesterol efflux.
Biochemical and biophysical research communications 2002;299(5):801-5.
2002: Miriam Lee; Laura Calabresi; Giulia Chiesa; Guido Franceschini; Petri T Kovanen
Mast cell chymase degrades apoE and apoA-II in apoA-I-knockout mouse plasma and reduces its ability to promote cellular cholesterol efflux.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(9):1475-81.
2002: Elisabetta Gianazza; Ivano Eberini; Cesare R Sirtori; Guido Franceschini; Laura Calabresi
Size is a major determinant of dissociation and denaturation behaviour of reconstituted high-density lipoproteins.
The Biochemical journal 2002;366(Pt 1):245-53.
2002: Giulia Chiesa; Elena Monteggia; Marta Marchesi; Paolo Lorenzon; Massimo Laucello; Vito Lorusso; Carlo Di Mario; Evangelia Karvouni; Roger S Newton; Charles L Bisgaier; Guido Franceschini; Cesare R Sirtori
Recombinant apolipoprotein A-I(Milano) infusion into rabbit carotid artery rapidly removes lipid from fatty streaks.
Circulation research 2002;90(9):974-80.
2002: Laura Calabresi; Monica Gomaraschi; Barbara Villa; Laura Omoboni; Camille Dmitrieff; Guido Franceschini
Elevated soluble cellular adhesion molecules in subjects with low HDL-cholesterol.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(4):656-61.
2002: Sara Deakin; Ilia Leviev; Monica Gomaraschi; Laura Calabresi; Guido Franceschini; Richard W James
Enzymatically active paraoxonase-1 is located at the external membrane of producing cells and released by a high affinity, saturable, desorption mechanism.
The Journal of biological chemistry 2002;277(6):4301-8.
2002: Damiano Baldassarre; Mauro Amato; Linda Pustina; Elena Tremoli; Cesare R Sirtori; Laura Calabresi; Guido Franceschini
Increased carotid artery intima-media thickness in subjects with primary hypoalphalipoproteinemia.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(2):317-22.
2001: Giulia Chiesa; Carlo Di Mario; N Colombo; L Vignati; Marta Marchesi; Elena Monteggia; Cinzia Parolini; P Lorenzon; M Laucello; Vito Lorusso; M Adamian; Guido Franceschini; R Newton; Cesare R Sirtori
Development of a lipid-rich, soft plaque in rabbits, monitored by histology and intravascular ultrasound.
Atherosclerosis 2001;156(2):277-87.
2001: Laura Calabresi; Gabriella Tedeschi; C Treu; Severino Ronchi; D Galbiati; S Airoldi; Cesare R Sirtori; Y Marcel; Guido Franceschini
Limited proteolysis of a disulfide-linked apoA-I dimer in reconstituted HDL.
Journal of lipid research 2001;42(6):935-42.
2001: Cesare R Sirtori; Laura Calabresi; Guido Franceschini; Damiano Baldassarre; Mauro Amato; J Johansson; Massimo Salvetti; Cristina Monteduro; R Zulli; Maria Lorenza Muiesan; Enrico Agabiti-Rosei
Cardiovascular status of carriers of the apolipoprotein A-I(Milano) mutant: the Limone sul Garda study.
Circulation 2001;103(15):1949-54.
2001: Stefano Bertolini; Livia Pisciotta; Marco Seri; Roberto Cusano; Alfredo Cantafora; Laura Calabresi; Guido Franceschini; Roberto Ravazzolo; Sebastiano Calandra
A point mutation in ABC1 gene in a patient with severe premature coronary heart disease and mild clinical phenotype of Tangier disease.
Atherosclerosis 2001;154(3):599-605.
2000: Laura Calabresi; D Donati; Franco Pazzucconi; Cesare R Sirtori; Guido Franceschini
Omacor in familial combined hyperlipidemia: effects on lipids and low density lipoprotein subclasses.
Atherosclerosis 2000;148(2):387-96.
1999: Laura Calabresi; Monica Canavesi; Franco Bernini; Guido Franceschini
Cell cholesterol efflux to reconstituted high-density lipoproteins containing the apolipoprotein A-IMilano dimer.
Biochemistry 1999;38(49):16307-14.
1999: Guido Franceschini; Laura Calabresi; Giulia Chiesa; Cinzia Parolini; Cesare R Sirtori; Monica Canavesi; Franco Bernini
Increased cholesterol efflux potential of sera from ApoA-IMilano carriers and transgenic mice.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(5):1257-62.
1999: Cesare R Sirtori; Laura Calabresi; Guido Franceschini
Recombinant apolipoproteins for the treatment of vascular diseases.
Atherosclerosis 1999;142(1):29-40.
1998: Giulia Chiesa; Cinzia Parolini; Monica Canavesi; N Colombo; Cesare R Sirtori; Remo Fumagalli; Guido Franceschini; Franco Bernini
Human apolipoproteins A-I and A-II in cell cholesterol efflux: studies with transgenic mice.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(9):1417-23.
1998: Richard W James; Marie-Claude Blatter Garin; Laura Calabresi; R Miccoli; A von Eckardstein; M Tilly-Kiesi; M R Taskinen; G Assmann; Guido Franceschini
Modulated serum activities and concentrations of paraoxonase in high density lipoprotein deficiency states.
Atherosclerosis 1998;139(1):77-82.
1998: Giulia Chiesa; LJ Stoltzfus; S Michelagnoli; John K Bielicki; M Santi; Trudy M Forte; Cesare R Sirtori; Guido Franceschini; Edward M Rubin
Elevated triglycerides and low HDL cholesterol in transgenic mice expressing human apolipoprotein A-I(Milano).
Atherosclerosis 1998;136(1):139-46.
1997: Damiano Baldassarre; Guido Franceschini; Giulia Peruzzotti; B Brusoni; Cesare R Sirtori
Clinical evaluation of probucol in hypercholesteremia: individual lipoprotein responses and inhibitory effect on carotid atherosclerosis progression.
Journal of cardiovascular pharmacology 1997;30(6):784-9.
1997: John K Bielicki; Trudy M Forte; Mark R McCall; LJ Stoltzfus; Giulia Chiesa; Cesare R Sirtori; Guido Franceschini; Edward M Rubin
High density lipoprotein particle size restriction in apolipoprotein A-I(Milano) transgenic mice.
Journal of lipid research 1997;38(11):2314-21.
1997: Laura Calabresi; G Vecchio; F Frigerio; L Vavassori; Cesare R Sirtori; Guido Franceschini
Reconstituted high-density lipoproteins with a disulfide-linked apolipoprotein A-I dimer: evidence for restricted particle size heterogeneity.
Biochemistry 1997;36(41):12428-33.
1997: Laura Calabresi; Guido Franceschini; Cesare R Sirtori; A De Palma; Marina Saresella; P Ferrante; Donatella Taramelli
Inhibition of VCAM-1 expression in endothelial cells by reconstituted high density lipoproteins.
Biochemical and biophysical research communications 1997;238(1):61-5.
1997: Laura Calabresi; Guido Franceschini
High density lipoprotein and coronary heart disease: insights from mutations leading to low high density lipoprotein.
Current opinion in lipidology 1997;8(4):219-24.
1997: Elisabetta Gianazza; Laura Calabresi; O Santi; Cesare R Sirtori; Guido Franceschini
Denaturation and self-association of apolipoprotein A-I investigated by electrophoretic techniques.
Biochemistry 1997;36(25):7898-905.
1997: Laura Calabresi; Guido Franceschini; A Burkybile; A Jonas
Activation of lecithin cholesterol acyltransferase by a disulfide-linked apolipoprotein A-I dimer.
Biochemical and biophysical research communications 1997;232(2):345-9.
1997: Marco Racchi; Roberta Baetta; N Salvietti; P Ianna; Guido Franceschini; Rodolfo Paoletti; Remo Fumagalli; Stefano Govoni; Marco Trabucchi; MR Soma
Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content.
The Biochemical journal 1997;322 ( Pt 3)():893-8.
1996: Laura Calabresi; A Lucchini; G Vecchio; Cesare R Sirtori; Guido Franceschini
Human apolipoprotein A-II inhibits the formation of pre-beta high density lipoproteins.
Biochimica et biophysica acta 1996;1304(1):32-42.
1996: Franco Pazzucconi; Guido Franceschini; G Gianfranceschi; G Campagnoli; Cesare R Sirtori
Cholesterol synthesis inhibitors do not reduce Lp(a) levels in normocholesterolemic patients.
Pharmacological research : the official journal of the Italian Pharmacological Society 1996;34(3-4):131-3.
1996: Guido Franceschini
Apolipoprotein function in health and disease: insights from natural mutations.
European journal of clinical investigation 1996;26(9):733-46.
1996: Damiano Baldassarre; Elena Tremoli; Guido Franceschini; S Michelagnoli; Cesare R Sirtori
Plasma lipoprotein(a) is an independent factor associated with carotid wall thickening in severely but not moderately hypercholesterolemic patients.
Stroke; a journal of cerebral circulation 1996;27(6):1044-9.
1995: T Murakami; S Michelagnoli; R Longhi; G Gianfranceschi; Franco Pazzucconi; Laura Calabresi; Cesare R Sirtori; Guido Franceschini
Triglycerides are major determinants of cholesterol esterification/transfer and HDL remodeling in human plasma.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(11):1819-28.
1995: Franco Pazzucconi; F Dorigotti; G Gianfranceschi; G Campagnoli; M Sirtori; Guido Franceschini; Cesare R Sirtori
Therapy with HMG CoA reductase inhibitors: characteristics of the long-term permanence of hypocholesterolemic activity.
Atherosclerosis 1995;117(2):189-98.
1995: Guido Franceschini; Elisabetta Cofrancesco; omid safa; C Boschetti; Elena Tremoli; Luciana Mussoni; Cesare R Sirtori; Michele Cortellaro
Association of lipoprotein(a) with atherothrombotic events and fibrinolytic variables. A case-control study.
Thrombosis research 1995;78(3):227-38.
1995: Guido Franceschini; Maria Rosa Lovati; C Manzoni; S Michelagnoli; Franco Pazzucconi; G Gianfranceschi; G Vecchio; Cesare R Sirtori
Effect of gemfibrozil treatment in hypercholesterolemia on low density lipoprotein (LDL) subclass distribution and LDL-cell interaction.
Atherosclerosis 1995;114(1):61-71.
1995: Guido Franceschini; J P Werba; A L D'Acquarica; G Gianfranceschi; S Michelagnoli; Cesare R Sirtori
Microsomal enzyme inducers raise plasma high-density lipoprotein cholesterol levels in healthy control subjects but not in patients with primary hypoalphalipoproteinemia.
Clinical pharmacology and therapeutics 1995;57(4):434-40.
1995: MR Soma; Elena Donetti; Cinzia Parolini; Cesare R Sirtori; Remo Fumagalli; Guido Franceschini
Recombinant apolipoprotein A-IMilano dimer inhibits carotid intimal thickening induced by perivascular manipulation in rabbits.
Circulation research 1995;76(3):405-11.
1994: Guido Franceschini; M Cassinotti; G Vecchio; G Gianfranceschi; Franco Pazzucconi; T Murakami; M Sirtori; A L D'Acquarica; Cesare R Sirtori
Pravastatin effectively lowers LDL cholesterol in familial combined hyperlipidemia without changing LDL subclass pattern.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(10):1569-75.
1994: Guido Franceschini; J P Werba; Laura Calabresi
Drug control of reverse cholesterol transport.
Pharmacology & therapeutics 1994;61(3):289-324.
1993: Guido Franceschini; J P Werba; omid safa; I Gikalov; Cesare R Sirtori
Dose-related increase of HDL-cholesterol levels after N-acetylcysteine in man.
Pharmacological research : the official journal of the Italian Pharmacological Society 1993;28(3):213-8.
1993: Franco Pazzucconi; Guido Franceschini; G Gianfranceschi; E Brambilla; Cesare R Sirtori
Lipoprotein structure in male subjects during in vivo lipolysis: effect of an anti-lipolytic treatment with acipimox.
Journal of lipid research 1993;34(9):1465-72.
1993: J P Werba; omid safa; G Gianfranceschi; S Michelagnoli; Cesare R Sirtori; Guido Franceschini
Plasma triglycerides and lipoprotein(a): inverse relationship in a hyperlipidemic Italian population.
Atherosclerosis 1993;101(2):203-11.
1993: Guido Franceschini; Rodolfo Paoletti
Pharmacological control of hypertriglyceridemia.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1993;7(3):297-302.
1993: Laura Calabresi; M Cassinotti; G Gianfranceschi; omid safa; T Murakami; Cesare R Sirtori; Guido Franceschini
Increased postprandial lipemia in Apo A-IMilano carriers.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(4):521-8.
1993: Guido Franceschini; Rodolfo Paoletti
Drugs controlling triglyceride metabolism.
Medicinal research reviews 1993;13(2):125-38.
1993: Giulia Chiesa; S Michelagnoli; M Cassinotti; G Gianfranceschi; J P Werba; Franco Pazzucconi; Cesare R Sirtori; Guido Franceschini
Mechanisms of high-density lipoprotein reduction after probucol treatment: changes in plasma cholesterol esterification/transfer and lipase activities.
Metabolism: clinical and experimental 1993;42(2):229-35.
1992: Cesare R Sirtori; Laura Calabresi; J P Werba; Guido Franceschini
Tolerability of fibric acids. Comparative data and biochemical bases.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26(3):243-60.
1992: Cesare R Sirtori; E Gatti; Elena Tremoli; Claudio Galli; G Gianfranceschi; Guido Franceschini; Susanna Colli; P Maderna; F Marangoni; P Perego
Olive oil, corn oil, and n-3 fatty acids differently affect lipids, lipoproteins, platelets, and superoxide formation in type II hypercholesterolemia.
The American journal of clinical nutrition 1992;56(1):113-22.
1992: Cesare R Sirtori; Guido Franceschini; G Gianfranceschi; Viola Vaccarino; Giulia Chiesa; P Maderna; M Bertoli; Laura Calabresi
Activity profile of gemfibrozil on the major plasma lipoprotein parameters.
European journal of epidemiology 1992;8 Suppl 1():120-4.
1992: Laura Calabresi; Cristina Banfi; Cesare R Sirtori; Guido Franceschini
Apolipoprotein A-II modulates HDL remodeling in plasma.
Biochimica et biophysica acta 1992;1124(2):195-8.
1992: Franco Pazzucconi; L Mannucci; Luciana Mussoni; G Gianfranceschi; P Maderna; P Werba; Guido Franceschini; Cesare R Sirtori; Elena Tremoli
Bezafibrate lowers plasma lipids, fibrinogen and platelet aggregability in hypertriglyceridaemia.
European journal of clinical pharmacology 1992;43(3):219-23.
1991: Guido Franceschini; Laura Calabresi; P Maderna; Claudio Galli; G Gianfranceschi; Cesare R Sirtori
Omega-3 fatty acids selectively raise high-density lipoprotein 2 levels in healthy volunteers.
Metabolism: clinical and experimental 1991;40(12):1283-6.
1991: Guido Franceschini; Giulia Chiesa; Cesare R Sirtori
Probucol increases cholesteryl ester transfer protein activity in hypercholesterolaemic patients.
European journal of clinical investigation 1991;21(4):384-8.
1991: Cesare R Sirtori; Alberico L Catapano; Guido Franceschini; Alberto Corsini; G Noseda; C Fragiacomo; E Panzeri; Viola Vaccarino; S Guenzi; Giorgio Casari
Aortic and coronary atheromatosis in a woman with severe hypercholesterolaemia without LDL receptor alterations.
European heart journal 1991;12(7):818-24.
1991: Guido Franceschini; P Maderna; Cesare R Sirtori
Reverse cholesterol transport: physiology and pharmacology.
Atherosclerosis 1991;88(2-3):99-107.
1991: Guido Franceschini; Ghil Busnach; Giulia Chiesa; Cesare R Sirtori
Management of lipoprotein-X accumulation in severe cholestasis by semi-selective LDL-apheresis.
The American journal of medicine 1991;90(5):633-8.
1991: Ghil Busnach; Guido Franceschini; Giulia Chiesa; Bruno Brando; A Cappelleri; L Isa; L Minetti
Impaired efficacy of selective LDL-apheresis in primary biliary cirrhosis.
The International journal of artificial organs 1991;14(4):246-50.
1991: Guido Franceschini; Ghil Busnach; Laura Calabresi; Giulia Chiesa; G Gianfranceschi; F Zoppi; L Minetti; Cesare R Sirtori
Predictability of low-density lipoprotein levels during apheretic treatment of hypercholesterolaemia.
European journal of clinical investigation 1991;21(2):209-14.
1991: Franco Pazzucconi; B Malavasi; Giovanni Galli; Guido Franceschini; Laura Calabresi; Cesare R Sirtori
Inhibition of antipyrine metabolism by low-dose contraceptives with gestodene and desogestrel.
Clinical pharmacology and therapeutics 1991;49(3):278-84.
1991: Guido Franceschini; Franco Bernini; S Michelagnoli; Stefano Bellosta; Viola Vaccarino; C Torre; Franco Pazzucconi; Remo Fumagalli; Cesare R Sirtori
Increased affinity of LDL for their receptors after acipimox treatment in hypertriglyceridemia.
European journal of clinical pharmacology 1991;40 Suppl 1():S45-8.
1990: Cesare R Sirtori; Laura Calabresi; Guido Franceschini; G Gianfranceschi; F Zoppi; S Winkler; P Bilotta; A Zampetti
Comparison of the lipoprotein and hemostatic changes after a triphasic and a monophasic low dose oral contraceptive in premenopausal middle-aged women.
Atherosclerosis 1990;84(2-3):203-11.
1990: Laura Calabresi; Guido Franceschini; M Sirtori; G Gianfranceschi; P Werba; Cesare R Sirtori
Influence of serum triglycerides on the HDL pattern in normal subjects and patients with coronary artery disease.
Atherosclerosis 1990;84(1):41-8.
1990: Giulia Chiesa; Guido Franceschini; Cesare R Sirtori
In vitro activity of probucol on cholesteryl ester transport.
Biochimica et biophysica acta 1990;1045(3):302-4.
1990: Guido Franceschini; Laura Calabresi; C Tosi; G Gianfranceschi; Cesare R Sirtori; A V Nichols
Apolipoprotein AIMilano. Disulfide-linked dimers increase high density lipoprotein stability and hinder particle interconversion in carrier plasma.
The Journal of biological chemistry 1990;265(21):12224-31.
1990: Guido Franceschini; M Baio; Laura Calabresi; Cesare R Sirtori; M C Cheung
Apolipoprotein AIMilano. Partial lecithin:cholesterol acyltransferase deficiency due to low levels of a functional enzyme.
Biochimica et biophysica acta 1990;1043(1):1-6.
1990: Guido Franceschini; Franco Bernini; S Michelagnoli; Stefano Bellosta; Viola Vaccarino; Remo Fumagalli; Cesare R Sirtori
Lipoprotein changes and increased affinity of LDL for their receptors after acipimox treatment in hypertriglyceridemia.
Atherosclerosis 1990;81(1):41-9.
1989: Guido Franceschini; M Sirtori; Viola Vaccarino; G Gianfranceschi; Giulia Chiesa; Cesare R Sirtori
Plasma lipoprotein changes after treatment with pravastatin and gemfibrozil in patients with familial hypercholesterolemia.
The Journal of laboratory and clinical medicine 1989;114(3):250-9.
1989: Guido Franceschini; M Sirtori; Viola Vaccarino; G Gianfranceschi; L Rezzonico; Giulia Chiesa; Cesare R Sirtori
Mechanisms of HDL reduction after probucol. Changes in HDL subfractions and increased reverse cholesteryl ester transfer.
Arteriosclerosis (Dallas, Tex.) 1989;9(4):462-9.
1989: Guido Franceschini; Laura Calabresi; Giulia Chiesa; Viola Vaccarino; M Sirtori; Cesare R Sirtori
Effects of probucol on the high density lipoprotein system in hypercholesterolaemic patients.
Pharmacological research : the official journal of the Italian Pharmacological Society 1989;21(1):113-4.
1988: Guido Franceschini; Ghil Busnach; Viola Vaccarino; Laura Calabresi; G Gianfranceschi; Cesare R Sirtori
Apheretic treatment of severe familial hypercholesterolemia: comparison of dextran sulfate cellulose and double membrane filtration methods for low density lipoprotein removal.
Atherosclerosis 1988;73(2-3):197-202.
1988: Guido Franceschini; Y Moreno; P Apebe; Laura Calabresi; E Gatti; D Noè; Emma De Fabiani; F Zoppi; Cesare R Sirtori
Alterations in high-density lipoprotein subfractions during postprandial lipidaemia induced by fat with and without ethanol.
Clinical science (London, England : 1979) 1988;75(2):135-42.
1988: Guido Franceschini; P Apebe; Laura Calabresi; Ghil Busnach; L Minetti; Viola Vaccarino; Cesare R Sirtori
Alterations in the HDL system after rapid plasma cholesterol reduction by LDL-apheresis.
Metabolism: clinical and experimental 1988;37(8):752-7.
1988: Cesare R Sirtori; M Sirtori; Laura Calabresi; Guido Franceschini
Changes in high-density lipoprotein subfraction distribution and increased cholesteryl ester transfer after probucol.
The American journal of cardiology 1988;62(3):73B-76B.
1988: Ghil Busnach; A Cappelleri; Viola Vaccarino; Guido Franceschini; A Dal Col; M L Perrino; Bruno Brando; Cesare R Sirtori; L Minetti
Selective and semiselective low-density lipoprotein apheresis in familial hypercholesterolemia.
Blood purification 1988;6(3):156-61.
1988: Cesare R Sirtori; Guido Franceschini
Effects of fibrates on serum lipids and atherosclerosis.
Pharmacology & therapeutics 1988;37(2):167-91.
1988: Guido Franceschini; Laura Calabresi; Cesare R Sirtori
Apolipoprotein AI-Milano: altered lipid binding properties in a human apolipoprotein variant.
Progress in clinical and biological research 1988;255():73-80.
1988: Guido Franceschini; Laura Calabresi; Viola Vaccarino; Ghil Busnach; A Cappelleri; Cesare R Sirtori
Comparison of dextran sulphate cellulose and double filtration plasmaphereses for the treatment of severe hypercholesterolemia.
Beiträge zur Infusionstherapie = Contributions to infusion therapy 1988;23():112-7.
1987: Guido Franceschini; A Bondioli; D Granata; V Mercuri; M Negri; C Tosi; Cesare R Sirtori
Reduced HDL2 levels in myocardial infarction patients without risk factors for atherosclerosis.
Atherosclerosis 1987;68(3):213-9.
1987: G Montanari; Viola Vaccarino; Guido Franceschini; M Sirtori; A Bondioli; Cesare R Sirtori
Metabolic approach to the diagnosis and treatment of atherosclerotic peripheral vascular disease.
International angiology : a journal of the International Union of Angiology 1987;6(4):339-49.
1987: Cesare R Sirtori; Guido Franceschini; G Gianfranceschi; M Sirtori; G Montanari; E Tremoli; P Maderna; Susanna Colli; F Zoppi
Effects of gemfibrozil on plasma lipoprotein-apolipoprotein distribution and platelet reactivity in patients with hypertriglyceridemia.
The Journal of laboratory and clinical medicine 1987;110(3):279-86.
1987: Guido Franceschini; Laura Calabresi; C Tosi; Cesare R Sirtori; C Fragiacomo; G Noseda; E Gong; P Blanche; A V Nichols
Apolipoprotein A-IMilano. Correlation between high density lipoprotein subclass distribution and triglyceridemia.
Arteriosclerosis (Dallas, Tex.) 1987;7(4):426-35.
1984: Cesare R Sirtori; Guido Franceschini; G Gianfranceschi; M Sirtori; G Montanari; E Bosisio; E Mantero; A Bondioli
Metformin improves peripheral vascular flow in nonhyperlipidemic patients with arterial disease.
Journal of cardiovascular pharmacology 1984;6(5):914-23.
1983: G Noseda; C Fragiacomo; R Cairoli; L Margon; Guido Franceschini; Cesare R Sirtori
[Separation of high density lipoproteins (HDL) using zonal ultracentrifugation in patients with apolipoprotein AI Milano variant].
Schweizerische medizinische Wochenschrift 1983;113(50):1933-5.
1982: Guido Franceschini; T G Frosi; C Manzoni; G Gianfranceschi; Cesare R Sirtori
High density lipoprotein-3 heterogeneity in subjects with the apo-AIMilano variant.
The Journal of biological chemistry 1982;257(17):9926-30.
1982: Guido Franceschini; A Bondioli; M Mantero; M Sirtori; G Tattoni; G Biasi; Cesare R Sirtori
Increased apoprotein B in very low density lipoproteins of patients with peripheral vascular disease.
Arteriosclerosis (Dallas, Tex.) 1982;2(1):74-80.
1981: Guido Franceschini; A Poli; A L Catapano; E Gatti; M Sirtori; G Gianfranceschi; Cesare R Sirtori
Pharmacological studies on tiadenol in type IV patients. Evidence for a mechanism of action different from other lipid-lowering drugs.
Atherosclerosis 1981;40(3-4):245-55.