Blas Frangione

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Revesz Tamas; Holton Janice L; Lashley Tammaryn; Plant Gordon; Frangione Blas; Rostagno Agueda; Ghiso Jorge
Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies.
Trouche Stéphanie G; Asuni Ayodeji; Rouland Sylvie; Wisniewski Thomas; Frangione Blas; Verdier Jean-Michel; Sigurdsson Einar M; Mestre-Francés Nadine
Antibody response and plasma Abeta1-40 levels in young Microcebus murinus primates immunized with Abeta1-42 and its derivatives.
Lashley T; Revesz T; Plant G; Bandopadhyay R; Lees A J; Frangione B; Wood N W; de Silva R; Ghiso J; Rostagno A; Holton J L
Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease.

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2009: Revesz Tamas; Holton Janice L; Lashley Tammaryn; Plant Gordon; Frangione Blas; Rostagno Agueda; Ghiso Jorge
Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies.
Acta neuropathologica 2009;118(1):115-30.
2009: Trouche Stéphanie G; Asuni Ayodeji; Rouland Sylvie; Wisniewski Thomas; Frangione Blas; Verdier Jean-Michel; Sigurdsson Einar M; Mestre-Francés Nadine
Antibody response and plasma Abeta1-40 levels in young Microcebus murinus primates immunized with Abeta1-42 and its derivatives.
Vaccine 2009;27(7):957-64.
2008: Lashley T; Revesz T; Plant G; Bandopadhyay R; Lees A J; Frangione B; Wood N W; de Silva R; Ghiso J; Rostagno A; Holton J L
Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease.
Neuropathology and applied neurobiology 2008;34(5):492-505.
2007: Westermark Per; Benson Merrill D; Buxbaum Joel N; Cohen Alan S; Frangione Blas; Ikeda Shu-Ichi; Masters Colin L; Merlini Giampaolo; Saraiva Maria J; Sipe Jean D
A primer of amyloid nomenclature.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2007;14(3):179-83.
2007: Rostagno Agueda; Lashley Tammaryn; Ng Douglas; Meyerson Jordana; Braendgaard Hans; Plant Gordon; Bojsen-Møller Marie; Holton Janice; Frangione Blas; Revesz Tamas; Ghiso Jorge
Preferential association of serum amyloid P component with fibrillar deposits in familial British and Danish dementias: similarities with Alzheimer's disease.
Journal of the neurological sciences 2007;257(1-2):88-96.
2007: Zanusso Gianluigi; Polo Alberto; Farinazzo Alessia; Nonno Romolo; Cardone Franco; Di Bari Michele; Ferrari Sergio; Principe Serena; Gelati Matteo; Fasoli Elisa; Fiorini Michele; Prelli Frances; Frangione Blas; Tridente Giuseppe; Bentivoglio Marina; Giorgi Alessandra; Schininà Maria Eugenia; Maras Bruno; Agrimi Umberto; Rizzuto Nicola; Pocchiari Maurizio; Monaco Salvatore
Novel prion protein conformation and glycotype in Creutzfeldt-Jakob disease.
Archives of neurology 2007;64(4):595-9.
2006: Asuni Ayodeji A; Boutajangout Allal; Scholtzova Henrieta; Knudsen Elin; Li Yong Sheng; Quartermain David; Frangione Blas; Wisniewski Thomas; Sigurdsson Einar M
Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages.
The European journal of neuroscience 2006;24(9):2530-42.
2006: Leal María C; Dorfman Verónica B; Gamba Agata Fernández; Frangione Blas; Wisniewski Thomas; Castaño Eduardo M; Sigurdsson Einar M; Morelli Laura
Plaque-associated overexpression of insulin-degrading enzyme in the cerebral cortex of aged transgenic tg2576 mice with Alzheimer pathology.
Journal of neuropathology and experimental neurology 2006;65(10):976-87.
2006: Lashley T; Holton J L; Verbeek M M; Rostagno A; Bojsen-Møller M; David G; van Horssen J; Braendgaard H; Plant G; Frangione B; Ghiso J; Revesz T
Molecular chaperons, amyloid and preamyloid lesions in the BRI2 gene-related dementias: a morphological study.
Neuropathology and applied neurobiology 2006;32(5):492-504.
2006: Ghiso J; Rostagno A; Tomidokoro Y; Lashley T; Bojsen-Møller M; Braendgaard H; Plant G; Holton J; Lal R; Revesz T; Frangione B
Genetic alterations of the BRI2 gene: familial British and Danish dementias.
Brain pathology (Zurich, Switzerland) 2006;16(1):71-9.
2006: Levy Efrat; Prelli Frances; Frangione Blas
Studies on the first described Alzheimer's disease amyloid beta mutant, the Dutch variant.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):329-39.
2005: Tomidokoro Yasushi; Lashley Tammaryn; Rostagno Agueda; Neubert Thomas A; Bojsen-Møller Marie; Braendgaard Hans; Plant Gordon; Holton Janice; Frangione Blas; Révész Tamas; Ghiso Jorge
Familial Danish dementia: co-existence of Danish and Alzheimer amyloid subunits (ADan AND A{beta}) in the absence of compact plaques.
The Journal of biological chemistry 2005;280(44):36883-94.
2005: Rábano Alberto; Jiménez-Huete Adolfo; Acevedo Boris; Calero Miguel; Ghiso Jorge; Valdés Israel; Gavilondo Jorge; Frangione Blas; Méndez Enrique
Diversity of senile plaques in Alzheimer's disease as revealed by a new monoclonal antibody that recognizes an internal sequence of the Abeta peptide.
Current Alzheimer research 2005;2(4):409-17.
2005: Fotinopoulou Angeliki; Tsachaki Maria; Vlavaki Maria; Poulopoulos Alexandros; Rostagno Agueda; Frangione Blas; Ghiso Jorge; Efthimiopoulos Spiros
BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production.
The Journal of biological chemistry 2005;280(35):30768-72.
2005: Matsuda Shuji; Giliberto Luca; Matsuda Yukiko; Davies Peter; McGowan Eileen; Pickford Fiona; Ghiso Jorge; Frangione Blas; D'Adamio Luciano
The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production.
The Journal of biological chemistry 2005;280(32):28912-6.
2005: Rostagno A; Tomidokoro Y; Lashley T; Ng D; Plant G; Holton J; Frangione B; Revesz T; Ghiso J
Chromosome 13 dementias.
Cellular and molecular life sciences : CMLS 2005;62(16):1814-25.
2005: Quist Arjan; Doudevski Ivo; Lin Hai; Azimova Rushana; Ng Douglas; Frangione Blas; Kagan Bruce; Ghiso Jorge; Lal Ratnesh
Amyloid ion channels: a common structural link for protein-misfolding disease.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(30):10427-32.
2005: Morelli Laura; Llovera Ramiro E; Alonso Leonardo G; Frangione Blas; de Prat-Gay Gonzalo; Ghiso Jorge; Castaño Eduardo M
Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia.
Biochemical and biophysical research communications 2005;332(3):808-16.
2005: Westermark Per; Benson Merrill D; Buxbaum Joel N; Cohen Alan S; Frangione Blas; Ikeda Shu-Ichi; Masters Colin L; Merlini Giampaolo; Saraiva Maria J; Sipe Jean D;
Amyloid: toward terminology clarification. Report from the Nomenclature Committee of the International Society of Amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2005;12(1):1-4.
2005: Wisniewski Thomas; Frangione Blas
Immunological and anti-chaperone therapeutic approaches for Alzheimer disease.
Brain pathology (Zurich, Switzerland) 2005;15(1):72-7.
2005: Prelli Frances; Pawlik Monika; Frangione Blas; Levy Efrat
Purification of human wild-type or variant cystatin C from conditioned media of transfected cells.
Methods in molecular biology (Clifton, N.J.) 2005;299():221-6.
2005: Calero Miguel; Rostagno Agueda; Frangione Blas; Ghiso Jorge
Clusterin and Alzheimer's disease.
Sub-cellular biochemistry 2005;38():273-98.
2004: Morelli Laura; Llovera Ramiro E; Mathov Irina; Lue Lih-Fen; Frangione Blas; Ghiso Jorge; Castaño Eduardo M
Insulin-degrading enzyme in brain microvessels: proteolysis of amyloid {beta} vasculotropic variants and reduced activity in cerebral amyloid angiopathy.
The Journal of biological chemistry 2004;279(53):56004-13.
2004: Ghiso Jorge; Shayo Marcos; Calero Miguel; Ng Douglas; Tomidokoro Yasushi; Gandy Samuel; Rostagno Agueda; Frangione Blas
Systemic catabolism of Alzheimer's Abeta40 and Abeta42.
The Journal of biological chemistry 2004;279(44):45897-908.
2004: Zanusso Gianluigi; Farinazzo Alessia; Prelli Frances; Fiorini Michele; Gelati Matteo; Ferrari Sergio; Righetti Pier Giorgio; Rizzuto Nicolò; Frangione Blas; Monaco Salvatore
Identification of distinct N-terminal truncated forms of prion protein in different Creutzfeldt-Jakob disease subtypes.
The Journal of biological chemistry 2004;279(37):38936-42.
2004: Sastre Magdalena; Calero Miguel; Pawlik Monika; Mathews Paul M; Kumar Asok; Danilov Vlatko; Schmidt Stephen D; Nixon Ralph A; Frangione Blas; Levy Efrat
Binding of cystatin C to Alzheimer's amyloid beta inhibits in vitro amyloid fibril formation.
Neurobiology of aging 2004;25(8):1033-43.
2004: Matsubara Etsuro; Sekijima Yoshiki; Tokuda Takahiko; Urakami Katsuya; Amari Masakuni; Shizuka-Ikeda Masami; Tomidokoro Yasushi; Ikeda Masaki; Kawarabayashi Takeshi; Harigaya Yasuo; Ikeda Shu-ichi; Murakami Tetsuro; Abe Koji; Otomo Eiichi; Hirai Shunsaku; Frangione Blas; Ghiso Jorge; Shoji Mikio
Soluble Abeta homeostasis in AD and DS: impairment of anti-amyloidogenic protection by lipoproteins.
Neurobiology of aging 2004;25(7):833-41.
2004: Sigurdsson Einar M; Knudsen Elin; Asuni Ayodeji; Fitzer-Attas Cheryl; Sage Daniel; Quartermain David; Goni Fernando; Frangione Blas; Wisniewski Thomas
An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-beta derivatives.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(28):6277-82.
2004: Cancela Martín; Carmona Carlos; Rossi Silvina; Frangione Blas; Goñi Fernando; Berasain Patricia
Purification, characterization, and immunolocalization of paramyosin from the adult stage of Fasciola hepatica.
Parasitology research 2004;92(6):441-8.
2004: Choi Seung-Il; Vidal Ruben; Frangione Blas; Levy Efrat
Axonal transport of British and Danish amyloid peptides via secretory vesicles.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(2):373-5.
2003: Sigurdsson Einar M; Brown David R; Alim Muhammad A; Scholtzova Henrieta; Carp Richard; Meeker Harry C; Prelli Frances; Frangione Blas; Wisniewski Thomas
Copper chelation delays the onset of prion disease.
The Journal of biological chemistry 2003;278(47):46199-202.
2003: Revesz Tamas; Ghiso Jorge; Lashley Tammaryn; Plant Gordon; Rostagno Agueda; Frangione Blas; Holton Janice L
Cerebral amyloid angiopathies: a pathologic, biochemical, and genetic view.
Journal of neuropathology and experimental neurology 2003;62(9):885-98.
2003: Berasain Patricia; Carmona Carlos; Frangione Blas; Cazzulo Juan José; Goñi Fernando
Specific cleavage sites on human IgG subclasses by cruzipain, the major cysteine proteinase from Trypanosoma cruzi.
Molecular and biochemical parasitology 2003;130(1):23-9.
2003: Deane Rashid; Du Yan Shi; Submamaryan Ram Kumar; LaRue Barbara; Jovanovic Suzana; Hogg Elizabeth; Welch Deborah; Manness Lawrence; Lin Chang; Yu Jin; Zhu Hong; Ghiso Jorge; Frangione Blas; Stern Alan; Schmidt Ann Marie; Armstrong Don L; Arnold Bernd; Liliensiek Birgit; Nawroth Peter; Hofman Florence; Kindy Mark; Stern David; Zlokovic Berislav
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.
Nature medicine 2003;9(7):907-13.
2003: Morelli Laura; Llovera Ramiro; Gonzalez Silvia A; Affranchino Jose L; Prelli Frances; Frangione Blas; Ghiso Jorge; Castano Eduardo M
Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme.
The Journal of biological chemistry 2003;278(26):23221-6.
2003: Sigurdsson Einar M; Sy Man-Sun; Li Ruliang; Scholtzova Henrieta; Kascsak Richard J; Kascsak Regina; Carp Richard; Meeker Harry C; Frangione Blas; Wisniewski Thomas
Anti-prion antibodies for prophylaxis following prion exposure in mice.
Neuroscience letters 2003;336(3):185-7.
2002: Ghiso Jorge; Frangione Blas
Amyloidosis and Alzheimer's disease.
Advanced drug delivery reviews 2002;54(12):1539-51.
2002: Rostagno Agueda; Revesz Tamas; Lashley Tammaryn; Tomidokoro Yasushi; Magnotti Laura; Braendgaard Hans; Plant Gordon; Bojsen-Møller Marie; Holton Janice; Frangione Blas; Ghiso Jorge
Complement activation in chromosome 13 dementias. Similarities with Alzheimer's disease.
The Journal of biological chemistry 2002;277(51):49782-90.
2002: Matsubara E; Shoji M; Murakami T; Abe K; Frangione B; Ghiso J
Platelet microparticles as carriers of soluble Alzheimer's amyloid beta (sAbeta).
Annals of the New York Academy of Sciences 2002;977():340-8.
2002: Sigurdsson Einar M; Wisniewski Thomas; Frangione Blas
A safer vaccine for Alzheimer's disease?
Neurobiology of aging 2002;23(6):1001-8.
2002: Westermark Per; Benson Merrill D; Buxbaum Joel N; Cohen Alan S; Frangione Blas; Ikeda Shu-ichi; Masters Colin L; Merlini Giampaolo; Saraiva Maria J; Sipe Jean D
Amyloid fibril protein nomenclature -- 2002.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2002;9(3):197-200.
2002: Sigurdsson Einar M; Wisniewski Thomas; Frangione Blas
Infectivity of amyloid diseases.
Trends in molecular medicine 2002;8(9):411-3.
2002: Revesz Tamas; Holton Janice L; Lashley Tammaryn; Plant Gordon; Rostagno Agueda; Ghiso Jorge; Frangione Blas
Sporadic and familial cerebral amyloid angiopathies.
Brain pathology (Zurich, Switzerland) 2002;12(3):343-57.
2002: Sigurdsson Einar M; Brown David R; Daniels Maki; Kascsak Richard J; Kascsak Regina; Carp Richard; Meeker Harry C; Frangione Blas; Wisniewski Thomas
Immunization delays the onset of prion disease in mice.
The American journal of pathology 2002;161(1):13-7.
2002: Mackic Jasmina B; Bading James; Ghiso Jorge; Walker Larry; Wisniewski Thomas; Frangione Blas; Zlokovic Berislav V
Circulating amyloid-beta peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions.
Vascular pharmacology 2002;38(6):303-13.
2002: Bading James R; Yamada Shinya; Mackic Jasmina B; Kirkman Linda; Miller Carol; Calero Miguel; Ghiso Jorge; Frangione Blas; Zlokovic Berislav V
Brain clearance of Alzheimer's amyloid-beta40 in the squirrel monkey: a SPECT study in a primate model of cerebral amyloid angiopathy.
Journal of drug targeting 2002;10(4):359-68.
2002: Monro O R; Mackic J B; Yamada S; Segal M B; Ghiso J; Maurer C; Calero M; Frangione B; Zlokovic B V
Substitution at codon 22 reduces clearance of Alzheimer's amyloid-beta peptide from the cerebrospinal fluid and prevents its transport from the central nervous system into blood.
Neurobiology of aging 2002;23(3):405-12.
2002: Holton Janice L; Lashley Tammaryn; Ghiso Jorge; Braendgaard Hans; Vidal Ruben; Guerin Christopher J; Gibb Graham; Hanger Diane P; Rostagno Agueda; Anderton Brian H; Strand Catherine; Ayling Hilary; Plant Gordon; Frangione Blas; Bojsen-Møller Marie; Revesz Tamas
Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta.
Journal of neuropathology and experimental neurology 2002;61(3):254-67.
2001: Ghiso J; Révész T; Holton J; Rostagno A; Lashley T; Houlden H; Gibb G; Anderton B; Bek T; Bojsen-Møller M; Wood N; Vidal R; Braendgaard H; Plant G; Frangione B
Chromosome 13 dementia syndromes as models of neurodegeneration.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2001;8(4):277-84.
2001: Poeggeler B; Miravalle L; Zagorski M G; Wisniewski T; Chyan Y J; Zhang Y; Shao H; Bryant-Thomas T; Vidal R; Frangione B; Ghiso J; Pappolla M A
Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide.
Biochemistry 2001;40(49):14995-5001.
2001: Ghiso J A; Holton J; Miravalle L; Calero M; Lashley T; Vidal R; Houlden H; Wood N; Neubert T A; Rostagno A; Plant G; Revesz T; Frangione B
Systemic amyloid deposits in familial British dementia.
The Journal of biological chemistry 2001;276(47):43909-14.
2001: Sigurdsson E M; Scholtzova H; Mehta P D; Frangione B; Wisniewski T
Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice.
The American journal of pathology 2001;159(2):439-47.
2001: Frangione B; Révész T; Vidal R; Holton J; Lashley T; Houlden H; Wood N; Rostagno A; Plant G; Ghiso J
Familial cerebral amyloid angiopathy related to stroke and dementia.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2001;8 Suppl 1():36-42.
2001: Calero M; Pawlik M; Soto C; Castaño E M; Sigurdsson E M; Kumar A; Gallo G; Frangione B; Levy E
Distinct properties of wild-type and the amyloidogenic human cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type.
Journal of neurochemistry 2001;77(2):628-37.
2001: Vidal R; Calero M; Révész T; Plant G; Ghiso J; Frangione B
Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family.
Gene 2001;266(1-2):95-102.
2001: Holton J L; Ghiso J; Lashley T; Rostagno A; Guerin C J; Gibb G; Houlden H; Ayling H; Martinian L; Anderton B H; Wood N W; Vidal R; Plant G; Frangione B; Revesz T
Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia.
The American journal of pathology 2001;158(2):515-26.
2001: Tagliavini F; Lievens P M; Tranchant C; Warter J M; Mohr M; Giaccone G; Perini F; Rossi G; Salmona M; Piccardo P; Ghetti B; Beavis R C; Bugiani O; Frangione B; Prelli F
A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Sträussler-Scheinker disease A117V.
The Journal of biological chemistry 2001;276(8):6009-15.
2000: Shibata M; Yamada S; Kumar S R; Calero M; Bading J; Frangione B; Holtzman D M; Miller C A; Strickland D K; Ghiso J; Zlokovic B V
Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier.
The Journal of clinical investigation 2000;106(12):1489-99.
2000: Vidal R; Ghiso J; Frangione B
New familial forms of cerebral amyloid and dementia.
Molecular psychiatry 2000;5(6):575-6.
2000: Miravalle L; Tokuda T; Chiarle R; Giaccone G; Bugiani O; Tagliavini F; Frangione B; Ghiso J
Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells.
The Journal of biological chemistry 2000;275(35):27110-6.
2000: Calero M; Rostagno A; Matsubara E; Zlokovic B; Frangione B; Ghiso J
Apolipoprotein J (clusterin) and Alzheimer's disease.
Microscopy research and technique 2000;50(4):305-15.
2000: Vidal R; Calero M; Piccardo P; Farlow M R; Unverzagt F W; Méndez E; Jiménez-Huete A; Beavis R; Gallo G; Gomez-Tortosa E; Ghiso J; Hyman B T; Frangione B; Ghetti B
Senile dementia associated with amyloid beta protein angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-epsilon4 allele.
Acta neuropathologica 2000;100(1):1-12.
2000: Zlokovic B V; Yamada S; Holtzman D; Ghiso J; Frangione B
Clearance of amyloid beta-peptide from brain: transport or metabolism?
Nature medicine 2000;6(7):718-9.
2000: Tokuda T; Calero M; Matsubara E; Vidal R; Kumar A; Permanne B; Zlokovic B; Smith J D; Ladu M J; Rostagno A; Frangione B; Ghiso J
Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides.
The Biochemical journal 2000;348 Pt 2():359-65.
2000: Mead S; James-Galton M; Revesz T; Doshi R B; Harwood G; Pan E L; Ghiso J; Frangione B; Plant G
Familial British dementia with amyloid angiopathy: early clinical, neuropsychological and imaging findings.
Brain : a journal of neurology 2000;123 ( Pt 5)():975-91.
2000: Ghiso J; Vidal R; Rostagno A; Mead S; Révész T; Plant G; Frangione B
A newly formed amyloidogenic fragment due to a stop codon mutation causes familial British dementia.
Annals of the New York Academy of Sciences 2000;903():129-37.
2000: Vidal R; Revesz T; Rostagno A; Kim E; Holton J L; Bek T; Bojsen-Møller M; Braendgaard H; Plant G; Ghiso J; Frangione B
A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4920-5.
2000: Askanas V; Engel W K; Alvarez R B; Frangione B; Ghiso J; Vidal R
Inclusion body myositis, muscle blood vessel and cardiac amyloidosis, and transthyretin Val122Ile allele.
Annals of neurology 2000;47(4):544-9.
2000: Berasain P; Carmona C; Frangione B; Dalton J P; Goñi F
Fasciola hepatica: parasite-secreted proteinases degrade all human IgG subclasses: determination of the specific cleavage sites and identification of the immunoglobulin fragments produced.
Experimental parasitology 2000;94(2):99-110.
2000: Strazielle N; Ghersi-Egea J F; Ghiso J; Dehouck M P; Frangione B; Patlak C; Fenstermacher J; Gorevic P
In vitro evidence that beta-amyloid peptide 1-40 diffuses across the blood-brain barrier and affects its permeability.
Journal of neuropathology and experimental neurology 2000;59(1):29-38.
2000: Sigurdsson E M; Permanne B; Soto C; Wisniewski T; Frangione B
In vivo reversal of amyloid-beta lesions in rat brain.
Journal of neuropathology and experimental neurology 2000;59(1):11-7.
2000: Soto C; Kascsak R J; Saborío G P; Aucouturier P; Wisniewski T; Prelli F; Kascsak R; Mendez E; Harris D A; Ironside J; Tagliavini F; Carp R I; Frangione B
Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides.
Lancet 2000;355(9199):192-7.
2000: Ghiso J; Vidal R; Rostagno A; Miravalle L; Holton J L; Mead S; Révész T; Plant G; Frangione B
Amyloidogenesis in familial British dementia is associated with a genetic defect on chromosome 13.
Annals of the New York Academy of Sciences 2000;920():84-92.
2000: Frangione B; Vidal R; Rostagno A; Ghiso J
Familial cerebral amyloid angiopathies and dementia.
Alzheimer disease and associated disorders 2000;14 Suppl 1():S25-30.
2000: Pappolla M A; Chyan Y J; Poeggeler B; Frangione B; Wilson G; Ghiso J; Reiter R J
An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(2):203-31.
1999: Rostagno A; Vidal R; Kaplan B; Chuba J; Kumar A; Elliott J I; Frangione B; Gallo G; Ghiso J
pH-dependent fibrillogenesis of a VkappaIII Bence Jones protein.
British journal of haematology 1999;107(4):835-43.
1999: Vidal R; Goñi F; Stevens F; Aucouturier P; Kumar A; Frangione B; Ghiso J; Gallo G
Somatic mutations of the L12a gene in V-kappa(1) light chain deposition disease: potential effects on aberrant protein conformation and deposition.
The American journal of pathology 1999;155(6):2009-17.
1999: Calero M; Tokuda T; Rostagno A; Kumar A; Zlokovic B; Frangione B; Ghiso J
Functional and structural properties of lipid-associated apolipoprotein J (clusterin).
The Biochemical journal 1999;344 Pt 2():375-83.
1999: Aucouturier P; Kascsak R J; Frangione B; Wisniewski T
Biochemical and conformational variability of human prion strains in sporadic Creutzfeldt-Jakob disease.
Neuroscience letters 1999;274(1):33-6.
1999: Chyan Y J; Poeggeler B; Omar R A; Chain D G; Frangione B; Ghiso J; Pappolla M A
Potent neuroprotective properties against the Alzheimer beta-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid.
The Journal of biological chemistry 1999;274(31):21937-42.
1999: Vidal R; Frangione B; Rostagno A; Mead S; Révész T; Plant G; Ghiso J
A stop-codon mutation in the BRI gene associated with familial British dementia.
Nature 1999;399(6738):776-81.
1999: Poduslo J F; Curran G L; Kumar A; Frangione B; Soto C
Beta-sheet breaker peptide inhibitor of Alzheimer's amyloidogenesis with increased blood-brain barrier permeability and resistance to proteolytic degradation in plasma.
Journal of neurobiology 1999;39(3):371-82.
1999: Saborío G P; Soto C; Kascsak R J; Levy E; Kascsak R; Harris D A; Frangione B
Cell-lysate conversion of prion protein into its protease-resistant isoform suggests the participation of a cellular chaperone.
Biochemical and biophysical research communications 1999;258(2):470-5.
1999: Déret S; Denoroy L; Lamarine M; Vidal R; Mougenot B; Frangione B; Stevens F J; Ronco P M; Aucouturier P
Kappa light chain-associated Fanconi's syndrome: molecular analysis of monoclonal immunoglobulin light chains from patients with and without intracellular crystals.
Protein engineering 1999;12(4):363-9.
1999: Matsubara E; Ghiso J; Frangione B; Amari M; Tomidokoro Y; Ikeda Y; Harigaya Y; Okamoto K; Shoji M
Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome.
Annals of neurology 1999;45(4):537-41.
1999: Aucouturier P; Frangione B; Wisniewski T
Prion diseases and the immune system.
Annales de médecine interne 1999;150(2):75-8.
1998: Jiménez-Huete A; Lievens P M; Vidal R; Piccardo P; Ghetti B; Tagliavini F; Frangione B; Prelli F
Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues.
The American journal of pathology 1998;153(5):1561-72.
1998: Crawford F; Soto C; Suo Z; Fang C; Parker T; Sawar A; Frangione B; Mullan M
Alzheimer's beta-amyloid vasoactivity: identification of a novel beta-amyloid conformational intermediate.
FEBS letters 1998;436(3):445-8.
1998: Wisniewski T; Aucouturier P; Soto C; Frangione B
The prionoses and other conformational disorders.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1998;5(3):212-24.
1998: Mackic J B; Stins M; McComb J G; Calero M; Ghiso J; Kim K S; Yan S D; Stern D; Schmidt A M; Frangione B; Zlokovic B V
Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer.
The Journal of clinical investigation 1998;102(4):734-43.
1998: Soto C; Sigurdsson E M; Morelli L; Kumar R A; Castaño E M; Frangione B
Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy.
Nature medicine 1998;4(7):822-6.
1998: Pappolla M; Bozner P; Soto C; Shao H; Robakis N K; Zagorski M; Frangione B; Ghiso J
Inhibition of Alzheimer beta-fibrillogenesis by melatonin.
The Journal of biological chemistry 1998;273(13):7185-8.
1998: Wisniewski T; Dowjat W K; Buxbaum J D; Khorkova O; Efthimiopoulos S; Kulczycki J; Lojkowska W; Wegiel J; Wisniewski H M; Frangione B
A novel Polish presenilin-1 mutation (P117L) is associated with familial Alzheimer's disease and leads to death as early as the age of 28 years.
Neuroreport 1998;9(2):217-21.
1998: Mackic J B; Weiss M H; Miao W; Kirkman E; Ghiso J; Calero M; Bading J; Frangione B; Zlokovic B V
Cerebrovascular accumulation and increased blood-brain barrier permeability to circulating Alzheimer's amyloid beta peptide in aged squirrel monkey with cerebral amyloid angiopathy.
Journal of neurochemistry 1998;70(1):210-5.
1997: Kaplan B; Vidal R; Kumar A; Ghiso J; Frangione B; Gallo G
Amino-terminal identity of co-existent amyloid and non-amyloid immunoglobulin kappa light chain deposits. A human disease to study alterations of protein conformation.
Clinical and experimental immunology 1997;110(3):472-8.
1997: Permanne B; Perez C; Soto C; Frangione B; Wisniewski T
Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants.
Biochemical and biophysical research communications 1997;240(3):715-20.
1997: Martel C L; Mackic J B; Matsubara E; Governale S; Miguel C; Miao W; McComb J G; Frangione B; Ghiso J; Zlokovic B V
Isoform-specific effects of apolipoproteins E2, E3, and E4 on cerebral capillary sequestration and blood-brain barrier transport of circulating Alzheimer's amyloid beta.
Journal of neurochemistry 1997;69(5):1995-2004.
1997: Wisniewski T; Dowjat W K; Permanne B; Palha J; Kumar A; Gallo G; Frangione B
Presenilin-1 is associated with Alzheimer's disease amyloid.
The American journal of pathology 1997;151(2):601-10.
1997: Ghiso J; Calero M; Matsubara E; Governale S; Chuba J; Beavis R; Wisniewski T; Frangione B
Alzheimer's soluble amyloid beta is a normal component of human urine.
FEBS letters 1997;408(1):105-8.
1997: Berasaín P; Goñi F; McGonigle S; Dowd A; Dalton J P; Frangione B; Carmona C
Proteinases secreted by Fasciola hepatica degrade extracellular matrix and basement membrane components.
The Journal of parasitology 1997;83(1):1-5.
1997: Wisniewski T; Ghiso J; Frangione B
Biology of A beta amyloid in Alzheimer's disease.
Neurobiology of disease 1997;4(5):313-28.
1996: Lalowski M; Golabek A; Lemere C A; Selkoe D J; Wisniewski H M; Beavis R C; Frangione B; Wisniewski T
The "nonamyloidogenic" p3 fragment (amyloid beta17-42) is a major constituent of Down's syndrome cerebellar preamyloid.
The Journal of biological chemistry 1996;271(52):33623-31.
1996: Castaño E M; Prelli F; Soto C; Beavis R; Matsubara E; Shoji M; Frangione B
The length of amyloid-beta in hereditary cerebral hemorrhage with amyloidosis, Dutch type. Implications for the role of amyloid-beta 1-42 in Alzheimer's disease.
The Journal of biological chemistry 1996;271(50):32185-91.
1996: Rostagno A; Vidal R; Kumar A; Chuba J; Niederman G; Gold L; Frangione B; Ghiso J; Gallo G
Fibrillary glomerulonephritis related to serum fibrillar immunoglobulin-fibronectin complexes.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1996;28(5):676-84.
1996: Piccardo P; Seiler C; Dlouhy S R; Young K; Farlow M R; Prelli F; Frangione B; Bugiani O; Tagliavini F; Ghetti B
Proteinase-K-resistant prion protein isoforms in Gerstmann-Sträussler-Scheinker disease (Indiana kindred).
Journal of neuropathology and experimental neurology 1996;55(11):1157-63.
1996: Soto C; Kindy M S; Baumann M; Frangione B
Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation.
Biochemical and biophysical research communications 1996;226(3):672-80.
1996: Vidal R; Ghiso J; Wisniewski T; Frangione B
Alzheimer's presenilin 1 gene expression in platelets and megakaryocytes. Identification of a novel splice variant.
FEBS letters 1996;393(1):19-23.
1996: Ghersi-Egea J F; Gorevic P D; Ghiso J; Frangione B; Patlak C S; Fenstermacher J D
Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries.
Journal of neurochemistry 1996;67(2):880-3.
1996: Perini F; Vidal R; Ghetti B; Tagliavini F; Frangione B; Prelli F
PrP27-30 is a normal soluble prion protein fragment released by human platelets.
Biochemical and biophysical research communications 1996;223(3):572-7.
1996: Matsubara E; Soto C; Governale S; Frangione B; Ghiso J
Apolipoprotein J and Alzheimer's amyloid beta solubility.
The Biochemical journal 1996;316 ( Pt 2)():671-9.
1996: Perini F; Frangione B; Prelli F
Prion protein released by platelets.
Lancet 1996;347(9015):1635-6.
1996: Gallo G; Goñi F; Boctor F; Vidal R; Kumar A; Stevens F J; Frangione B; Ghiso J
Light chain cardiomyopathy. Structural analysis of the light chain tissue deposits.
The American journal of pathology 1996;148(5):1397-406.
1996: Ghetti B; Piccardo P; Frangione B; Bugiani O; Giaccone G; Young K; Prelli F; Farlow M R; Dlouhy S R; Tagliavini F
Prion protein amyloidosis.
Brain pathology (Zurich, Switzerland) 1996;6(2):127-45.
1996: Rostagno A; Williams M; Frangione B; Gold L I
Biochemical analysis of the interaction of fibronectin with IgG and localization of the respective binding sites.
Molecular immunology 1996;33(6):561-72.
1996: Zlokovic B V; Martel C L; Matsubara E; McComb J G; Zheng G; McCluskey R T; Frangione B; Ghiso J
Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4229-34.
1996: Palha J A; Moreira P; Wisniewski T; Frangione B; Saraiva M J
Transthyretin gene in Alzheimer's disease patients.
Neuroscience letters 1996;204(3):212-4.
1996: Vidal R; Garzuly F; Budka H; Lalowski M; Linke R P; Brittig F; Frangione B; Wisniewski T
Meningocerebrovascular amyloidosis associated with a novel transthyretin mis-sense mutation at codon 18 (TTRD 18G)
The American journal of pathology 1996;148(2):361-6.
1996: Wisniewski T; Lalowski M; Baumann M; Rauvala H; Raulo E; Nolo R; Frangione B
HB-GAM is a cytokine present in Alzheimer's and Down's syndrome lesions.
Neuroreport 1996;7(2):667-71.
1996: Morelli L; Wei L; Amorim A; McDermid J; Abee C R; Frangione B; Walker L C; Levy E
Cerebrovascular amyloidosis in squirrel monkeys and rhesus monkeys: apolipoprotein E genotype.
FEBS letters 1996;379(2):132-4.
1996: Wisniewski T; Lalowski M; Bobik M; Russell M; Strosznajder J; Frangione B
Amyloid beta 1-42 deposits do not lead to Alzheimer's neuritic plaques in aged dogs.
The Biochemical journal 1996;313 ( Pt 2)():575-80.
1996: Ghetti B; Piccardo P; Spillantini M G; Ichimiya Y; Porro M; Perini F; Kitamoto T; Tateishi J; Seiler C; Frangione B; Bugiani O; Giaccone G; Prelli F; Goedert M; Dlouhy S R; Tagliavini F
Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):744-8.
1996: Giaccone G; Pedrotti B; Migheli A; Verga L; Perez J; Racagni G; Smith M A; Perry G; De Gioia L; Selvaggini C; Salmona M; Ghiso J; Frangione B; Islam K; Bugiani O; Tagliavini F
beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease.
The American journal of pathology 1996;148(1):79-87.
1996: Frangione B; Castaño E M; Wisniewski T; Ghiso J; Prelli F; Vidal R
Apolipoprotein E and amyloidogenesis.
Ciba Foundation symposium 1996;199():132-41; discussion 141-5.
1996: Wisniewski T; Frangione B
Molecular biology of brain aging and neurodegenerative disorders.
Acta neurobiologiae experimentalis 1996;56(1):267-79.
1995: Soto C; Castaño E M; Kumar R A; Beavis R C; Frangione B
Fibrillogenesis of synthetic amyloid-beta peptides is dependent on their initial secondary structure.
Neuroscience letters 1995;200(2):105-8.
1995: Wisniewski T; Palha J A; Ghiso J; Frangione B
S182 protein in Alzheimer's disease neuritic plaques.
Lancet 1995;346(8986):1366.
1995: Castaño E M; Prelli F C; Frangione B
Apolipoprotein E and amyloidogenesis.
Laboratory investigation; a journal of technical methods and pathology 1995;73(4):457-60.
1995: Levy E; Amorim A; Frangione B; Walker L C
beta-Amyloid precursor protein gene in squirrel monkeys with cerebral amyloid angiopathy.
Neurobiology of aging 1995;16(5):805-8.
1995: Wisniewski T; Frangione B
Amyloidosis in Alzheimer's disease.
Lancet 1995;346(8972):441.
1995: Wisniewski T; Golabek A A; Kida E; Wisniewski K E; Frangione B
Conformational mimicry in Alzheimer's disease. Role of apolipoproteins in amyloidogenesis.
The American journal of pathology 1995;147(2):238-44.
1995: Castaño E M; Frangione B
Non-Alzheimer's disease amyloidoses of the nervous system.
Current opinion in neurology 1995;8(4):279-85.
1995: Castaño E M; Prelli F; Pras M; Frangione B
Apolipoprotein E carboxyl-terminal fragments are complexed to amyloids A and L. Implications for amyloidogenesis and Alzheimer's disease.
The Journal of biological chemistry 1995;270(29):17610-5.
1995: Wattendorff A R; Frangione B; Luyendijk W; Bots G T
Hereditary cerebral haemorrhage with amyloidosis, Dutch type (HCHWA-D): clinicopathological studies.
Journal of neurology, neurosurgery, and psychiatry 1995;58(6):699-705.
1995: Wisniewski T; Lalowski M; Golabek A; Vogel T; Frangione B
Is Alzheimer's disease an apolipoprotein E amyloidosis?
Lancet 1995;345(8955):956-8.
1995: Smith M A; Siedlak S L; Richey P L; Mulvihill P; Ghiso J; Frangione B; Tagliavini F; Giaccone G; Bugiani O; Praprotnik D
Tau protein directly interacts with the amyloid beta-protein precursor: implications for Alzheimer's disease.
Nature medicine 1995;1(4):365-9.
1995: Bugiani O; Tagliavini F; Giaccone G; Verga L; el-Hachimi K; Foncin J F; Frangione B
Diffuse senile plaques: amorphous or fibrous?
The American journal of pathology 1995;146(3):777-9.
1995: Ghiso J; Plant G T; Révész T; Wisniewski T; Frangione B
Familial cerebral amyloid angiopathy (British type) with nonneuritic amyloid plaque formation may be due to a novel amyloid protein.
Journal of the neurological sciences 1995;129(1):74-5.
1995: Matsubara E; Frangione B; Ghiso J
Characterization of apolipoprotein J-Alzheimer's A beta interaction.
The Journal of biological chemistry 1995;270(13):7563-7.
1995: Castano E M; Prelli F; Wisniewski T; Golabek A; Kumar R A; Soto C; Frangione B
Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E.
The Biochemical journal 1995;306 ( Pt 2)():599-604.
1995: Soto C; Castaño E M; Frangione B; Inestrosa N C
The alpha-helical to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation.
The Journal of biological chemistry 1995;270(7):3063-7.
1995: Soto C; Frangione B
Two conformational states of amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease.
Neuroscience letters 1995;186(2-3):115-8.
1995: Wisniewski T; Morelli L; Wegiel J; Levy E; Wisniewski H M; Frangione B
The influence of apolipoprotein E isotypes on Alzheimer's disease pathology in 40 cases of Down's syndrome.
Annals of neurology 1995;37(1):136-8.
1995: Ghetti B; Dlouhy S R; Giaccone G; Bugiani O; Frangione B; Farlow M R; Tagliavini F
Gerstmann-Sträussler-Scheinker disease and the Indiana kindred.
Brain pathology (Zurich, Switzerland) 1995;5(1):61-75.
1995: Mangone C A; Castaño E M; Levy E; Abiusi G; Wisniewski T; Marques M R; Faccio E; Gorelick P B; Frangione B; Sica R E
Early onset Alzheimer's disease in a South American pedigree from Argentina.
Acta neurologica Scandinavica 1995;91(1):6-13.
1994: Zlokovic B V; Martel C L; Mackic J B; Matsubara E; Wisniewski T; McComb J G; Frangione B; Ghiso J
Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta.
Biochemical and biophysical research communications 1994;205(2):1431-7.
1994: Koudinov A; Matsubara E; Frangione B; Ghiso J
The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma.
Biochemical and biophysical research communications 1994;205(2):1164-71.
1994: Wisniewski T; Castaño E M; Golabek A; Vogel T; Frangione B
Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro.
The American journal of pathology 1994;145(5):1030-5.
1994: Tagliavini F; Prelli F; Porro M; Rossi G; Giaccone G; Farlow M R; Dlouhy S R; Ghetti B; Bugiani O; Frangione B
Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish kindreds) express only PrP peptides encoded by the mutant allele.
Cell 1994;79(4):695-703.
1994: Kivelä T; Tarkkanen A; Frangione B; Ghiso J; Haltia M
Ocular amyloid deposition in familial amyloidosis, Finnish: an analysis of native and variant gelsolin in Meretoja's syndrome.
Investigative ophthalmology & visual science 1994;35(10):3759-69.
1994: Gallo G; Wisniewski T; Choi-Miura N H; Ghiso J; Frangione B
Potential role of apolipoprotein-E in fibrillogenesis.
The American journal of pathology 1994;145(3):526-30.
1994: Sanan D A; Weisgraber K H; Russell S J; Mahley R W; Huang D; Saunders A; Schmechel D; Wisniewski T; Frangione B; Roses A D
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.
The Journal of clinical investigation 1994;94(2):860-9.
1994: Ghiso J; Gardella J E; Liem L; Gorevic P D; Frangione B
Characterization of a novel processing pathway for Alzheimer's amyloid beta precursor protein.
Neuroscience letters 1994;171(1-2):213-6.
1994: Gandy S; Caporaso G; Buxbaum J; Frangione B; Greengard P
APP processing, A beta-amyloidogenesis, and the pathogenesis of Alzheimer's disease.
Neurobiology of aging 1994;15(2):253-6.
1994: Wisniewski T; Ghiso J; Frangione B
Alzheimer's disease and soluble A beta.
Neurobiology of aging 1994;15(2):143-52.
1994: Wisniewski T; Lalowski M; Levy E; Marques M R; Frangione B
The amino acid sequence of neuritic plaque amyloid from a familial Alzheimer's disease patient.
Annals of neurology 1994;35(2):245-6.
1994: Ghiso J; Wisniewski T; Frangione B
Unifying features of systemic and cerebral amyloidosis.
Molecular neurobiology 1994;8(1):49-64.
1994: Ghetti B; Tagliavini F; Giaccone G; Bugiani O; Frangione B; Farlow M R; Dlouhy S R
Familial Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles.
Molecular neurobiology 1994;8(1):41-8.
1994: Frangione B; Wisniewski T; Ghiso J
Chaperoning Alzheimer's amyloids.
Neurobiology of aging 1994;15 Suppl 2():S97-9.
1993: Zlokovic B V; Ghiso J; Mackic J B; McComb J G; Weiss M H; Frangione B
Blood-brain barrier transport of circulating Alzheimer's amyloid beta.
Biochemical and biophysical research communications 1993;197(3):1034-40.
1993: Kivelä T; Tarkkanen A; McLean I; Ghiso J; Frangione B; Haltia M
Immunohistochemical analysis of lattice corneal dystrophies types I and II.
The British journal of ophthalmology 1993;77(12):799-804.
1993: Wisniewski T; Castano E; Ghiso J; Frangione B
Cerebrospinal fluid inhibits Alzheimer beta-amyloid fibril formation in vitro.
Annals of neurology 1993;34(4):631-3.
1993: Gardella J E; Gorgone G A; Candela L; Ghiso J; Castaño E M; Frangione B; Gorevic P D
High-level expression and in vitro mutagenesis of a fibrillogenic 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein.
The Biochemical journal 1993;294 ( Pt 3)():667-74.
1993: Tagliavini F; Giaccone G; Prelli F; Verga L; Porro M; Trojanowski J Q; Farlow M R; Frangione B; Ghetti B; Bugiani O
A68 is a component of paired helical filaments of Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Brain research 1993;616(1-2):325-9.
1993: Ghiso J; Matsubara E; Koudinov A; Choi-Miura N H; Tomita M; Wisniewski T; Frangione B
The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex.
The Biochemical journal 1993;293 ( Pt 1)():27-30.
1993: Goldfarb L G; Brown P; Haltia M; Ghiso J; Frangione B; Gajdusek D C
Synthetic peptides corresponding to different mutated regions of the amyloid gene in familial Creutzfeldt-Jakob disease show enhanced in vitro formation of morphologically different amyloid fibrils.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4451-4.
1993: Wisniewski T; Golabek A; Matsubara E; Ghiso J; Frangione B
Apolipoprotein E: binding to soluble Alzheimer's beta-amyloid.
Biochemical and biophysical research communications 1993;192(2):359-65.
1993: Ramabhadran T V; Gandy S E; Ghiso J; Czernik A J; Ferris D; Bhasin R; Goldgaber D; Frangione B; Greengard P
Proteolytic processing of human amyloid beta protein precursor in insect cells. Major carboxyl-terminal fragment is identical to its human counterpart.
The Journal of biological chemistry 1993;268(3):2009-12.
1993: Bugiani O; Giaccone G; Verga L; Pollo B; Frangione B; Farlow M R; Tagliavini F; Ghetti B
Beta PP participates in PrP-amyloid plaques of Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Journal of neuropathology and experimental neurology 1993;52(1):64-70.
1993: Tagliavini F; Giaccone G; Bugiani O; Frangione B
Ubiquitinated neurites are associated with preamyloid and cerebral amyloid beta deposits in patients with hereditary cerebral hemorrhage with amyloidosis Dutch type.
Acta neuropathologica 1993;85(3):267-71.
1993: Vidal R G; Fernandez-Madrid I; Frangione B; Levy E
Sequencing of the Alzheimer's APP gene Dutch variant (APP-D)
Human mutation 1993;2(6):496-7.
1992: Gold L I; Rostagno A; Frangione B; Passalaris T
Localization of the cleavage sites on fibronectin following digestion by urokinase.
Journal of cellular biochemistry 1992;50(4):441-52.
1992: Ghiso J; Rostagno A; Gardella J E; Liem L; Gorevic P D; Frangione B
A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion.
The Biochemical journal 1992;288 ( Pt 3)():1053-9.
1992: Shoji M; Golde T E; Ghiso J; Cheung T T; Estus S; Shaffer L M; Cai X D; McKay D M; Tintner R; Frangione B
Production of the Alzheimer amyloid beta protein by normal proteolytic processing.
Science (New York, N.Y.) 1992;258(5079):126-9.
1992: Vidal R G; Ghiso J; Gallo G; Cohen M; Gambetti P L; Frangione B
Amyloidoma of the CNS. II. Immunohistochemical and biochemical study.
Neurology 1992;42(10):2024-8.
1992: Giaccone G; Verga L; Bugiani O; Frangione B; Serban D; Prusiner S B; Farlow M R; Ghetti B; Tagliavini F
Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9349-53.
1992: Heyermann H; Butler J E; Frangione B
The heterogeneity of bovine IgG2--V. Differences in the primary structure of bovine IgG2 allotypes.
Molecular immunology 1992;29(9):1147-52.
1992: Gardella J E; Gorgone G A; Munoz P C; Ghiso J; Frangione B; Gorevic P D
Beta protein precursor expression in human platelets and a megakaryocyte cell line. Possible implications for the origin of cerebral amyloidosis in Alzheimer's disease.
Laboratory investigation; a journal of technical methods and pathology 1992;67(3):303-13.
1992: Tagliavini F; Prelli F; Porro M; Salmona M; Bugiani O; Frangione B
A soluble form of prion protein in human cerebrospinal fluid: implications for prion-related encephalopathies.
Biochemical and biophysical research communications 1992;184(3):1398-404.
1992: Ayadi H; Mihaesco E; Congy N; Roy J P; Gendron M C; Laperriere J; Prelli F; Frangione B; Brouet J C
H chain V region sequences of three human monoclonal IgM with anti-myelin-associated glycoprotein activity.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(9):2812-6.
1992: Gardella J E; Gorgone G A; Newman P; Frangione B; Gorevic P D
Characterization of Alzheimer amyloid precursor protein transcripts in platelets and megakarocytes.
Neuroscience letters 1992;138(2):229-32.
1992: Ghiso J; Wisniewski T; Vidal R; Rostagno A; Frangione B
Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease.
The Biochemical journal 1992;282 ( Pt 2)():517-22.
1992: Prelli F; Frangione B
Franklin's disease: Ig gamma 2 H chain mutant BUR.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(3):949-52.
1992: Wisniewski T; Frangione B
Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid.
Neuroscience letters 1992;135(2):235-8.
1992: Haltia M; Levy E; Meretoja J; Fernandez-Madrid I; Koivunen O; Frangione B
Gelsolin gene mutation--at codon 187--in familial amyloidosis, Finnish: DNA-diagnostic assay.
American journal of medical genetics 1992;42(3):357-9.
1992: Wisniewski T; Frangione B
Molecular biology of Alzheimer's amyloid--Dutch variant.
Molecular neurobiology 1992;6(1):75-86.
1992: Tagliavini F; Giaccone G; Verga L; Frangione B; Bugiani O
Down syndrome as a key to the time sequence of brain changes in Alzheimer disease.
Progress in clinical and biological research 1992;379():143-58.
1991: Gorevic P D; Munoz P C; Gorgone G; Purcell J J; Rodrigues M; Ghiso J; Levy E; Haltia M; Frangione B
Amyloidosis due to a mutation of the gelsolin gene in an American family with lattice corneal dystrophy type II.
The New England journal of medicine 1991;325(25):1780-5.
1991: Wisniewski T; Ghiso J; Frangione B
Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation.
Biochemical and biophysical research communications 1991;180(3):1528.
1991: Fernandez-Madrid I; Levy E; Marder K; Frangione B
Codon 618 variant of Alzheimer amyloid gene associated with inherited cerebral hemorrhage.
Annals of neurology 1991;30(5):730-3.
1991: Kuruvilla A P; Hochwald G M; Ghiso J; Castaño E M; Pizzolato M; Frangione B
Isolation and amino terminal sequence of beta-trace, a novel protein from human cerebrospinal fluid.
Brain research 1991;565(2):337-40.
1991: Levy E; Frangione B
Familial Alzheimer's disease.
Current biology : CB 1991;1(5):312-4.
1991: Castaño E M; Wisniewski T; Frangione B
Inherited amyloids of the nervous system.
Current opinion in neurobiology 1991;1(3):448-54.
1991: Wisniewski T; Ghiso J; Frangione B
Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation.
Biochemical and biophysical research communications 1991;179(3):1247-54.
1991: Bakker E; van Broeckhoven C; Haan J; Voorhoeve E; van Hul W; Levy E; Lieberburg I; Carman M D; van Ommen G J; Frangione B
DNA diagnosis for hereditary cerebral hemorrhage with amyloidosis (Dutch type)
American journal of human genetics 1991;49(3):518-21.
1991: Trau H; Shpiro D; Schewach-Millet M; Pras M; Prelli F; Frangione B
Nodular cutaneous amyloidosis.
The American Journal of dermatopathology 1991;13(4):414-7.
1991: el Hachimi K H; Verga L; Giaccone G; Tagliavini F; Frangione B; Bugiani O; Foncin J F
Relationship between non-fibrillary amyloid precursors and cell processes in the cortical neuropil of Alzheimer patients.
Neuroscience letters 1991;129(1):119-22.
1991: Tagliavini F; Giaccone G; Verga L; Ghiso J; Frangione B; Bugiani O
Alzheimer patients: preamyloid deposits are immunoreactive with antibodies to extracellular domains of the amyloid precursor protein.
Neuroscience letters 1991;128(1):117-20.
1991: Castaño E M; Frangione B
Alzheimer's disease from the perspective of the systemic and localized forms of amyloidosis.
Brain pathology (Zurich, Switzerland) 1991;1(4):263-71.
1991: Haltia M; Ghiso J; Wisniewski T; Kiuru S; Miller D; Frangione B
Gelsolin variant and beta-amyloid co-occur in a case of Alzheimer's with Lewy bodies.
Neurobiology of aging 1991;12(4):313-6.
1991: Prelli F; Pras M; Shtrasburg S; Frangione B
Characterization of high molecular weight amyloid A proteins.
Scandinavian journal of immunology 1991;33(6):783-6.
1991: Wisniewski T; Haltia M; Ghiso J; Frangione B
Lewy bodies are immunoreactive with antibodies raised to gelsolin related amyloid-Finnish type.
The American journal of pathology 1991;138(5):1077-83.
1991: Rostagno A A; Frangione B; Gold L
Biochemical studies on the interaction of fibronectin with Ig.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(8):2687-93.
1991: Gorevic P D; Frangione B
Mixed cryoglobulinemia cross-reactive idiotypes: implications for the relationship of MC to rheumatic and lymphoproliferative diseases.
Seminars in hematology 1991;28(2):79-94.
1991: Tagliavini F; Prelli F; Ghiso J; Bugiani O; Serban D; Prusiner S B; Farlow M R; Ghetti B; Frangione B
Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58.
The EMBO journal 1991;10(3):513-9.
1991: Leoni J; Ghiso J; Goñi F; Frangione B
The primary structure of the Fab fragment of protein KAU, a monoclonal immunoglobulin M cold agglutinin.
The Journal of biological chemistry 1991;266(5):2836-42.
1991: Gajdusek D C; Beyreuther K; Brown P; Cork L C; Cunningham D D; Frangione B; Gibbs C J; Goldfarb L G; Goldgaber D; Hsiao K K
Regulation and genetic control of brain amyloid. FESN Study Group.
Brain research. Brain research reviews 1991;16(1):83-114.
1990: Ghiso J; Haltia M; Prelli F; Novello J; Frangione B
Gelsolin variant (Asn-187) in familial amyloidosis, Finnish type.
The Biochemical journal 1990;272(3):827-30.
1990: Levy E; Haltia M; Fernandez-Madrid I; Koivunen O; Ghiso J; Prelli F; Frangione B
Mutation in gelsolin gene in Finnish hereditary amyloidosis.
The Journal of experimental medicine 1990;172(6):1865-7.
1990: Gardella J E; Ghiso J; Gorgone G A; Marratta D; Kaplan A P; Frangione B; Gorevic P D
Intact Alzheimer amyloid precursor protein (APP) is present in platelet membranes and is encoded by platelet mRNA.
Biochemical and biophysical research communications 1990;173(3):1292-8.
1990: Barnes J L; Goñi F; Heyermann H; Frangione B; Agnello V
Human rheumatoid factor cross-idiotypes. III. Bla monoclonal rheumatoid factor, prototype of the BLA cross-idiotype group, has distinct kappa chains related to the V kappa III subgroup and VH4 heavy chains.
Arthritis and rheumatism 1990;33(11):1710-5.
1990: Timmers W F; Tagliavini F; Haan J; Frangione B
Parenchymal preamyloid and amyloid deposits in the brains of patients with hereditary cerebral hemorrhage with amyloidosis--Dutch type.
Neuroscience letters 1990;118(2):223-6.
1990: Picken M M; Gallo G R; Frangione B
Amyloid enhancing factor and inflammatory reaction.
Laboratory investigation; a journal of technical methods and pathology 1990;63(4):586-7.
1990: Giaccone G; Tagliavini F; Verga L; Frangione B; Farlow M R; Bugiani O; Ghetti B
Neurofibrillary tangles of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease.
Brain research 1990;530(2):325-9.
1990: Marangoni S; Ghiso J; Sampaio S V; Arantes E C; Giglio J R; Oliveira B; Frangione B
The complete amino acid sequence of toxin TsTX-VI isolated from the venom of the scorpion Tityus serrulatus.
Journal of protein chemistry 1990;9(5):595-601.
1990: Bugiani O; Giaccone G; Verga L; Pollo B; Ghetti B; Frangione B; Tagliavini F
Alzheimer patients and Down patients: abnormal presynaptic terminals are related to cerebral preamyloid deposits.
Neuroscience letters 1990;119(1):56-9.
1990: Giaccone G; Verga L; Finazzi M; Pollo B; Tagliavini F; Frangione B; Bugiani O
Cerebral preamyloid deposits and congophilic angiopathy in aged dogs.
Neuroscience letters 1990;114(2):178-83.
1990: Prelli F; Levy E; van Duinen S G; Bots G T; Luyendijk W; Frangione B
Expression of a normal and variant Alzheimer's beta-protein gene in amyloid of hereditary cerebral hemorrhage, Dutch type: DNA and protein diagnostic assays.
Biochemical and biophysical research communications 1990;170(1):301-7.
1990: Haltia M; Ghiso J; Prelli F; Gallo G; Kiuru S; Somer H; Palo J; Frangione B
Amyloid in familial amyloidosis, Finnish type, is antigenically and structurally related to gelsolin.
The American journal of pathology 1990;136(6):1223-8.
1990: Picken M M; Gallo G R; Pruzanski W; Frangione B
Biochemical characterization of amyloid derived from the variable region of the kappa light chain subgroup III.
Arthritis and rheumatism 1990;33(6):880-4.
1990: Tagliavini F; Ghiso J; Timmers W F; Giaccone G; Bugiani O; Frangione B
Coexistence of Alzheimer's amyloid precursor protein and amyloid protein in cerebral vessel walls.
Laboratory investigation; a journal of technical methods and pathology 1990;62(6):761-7.
1990: Levy E; Carman M D; Fernandez-Madrid I J; Power M D; Lieberburg I; van Duinen S G; Bots G T; Luyendijk W; Frangione B
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.
Science (New York, N.Y.) 1990;248(4959):1124-6.
1990: Haltia M; Prelli F; Ghiso J; Kiuru S; Somer H; Palo J; Frangione B
Amyloid protein in familial amyloidosis (Finnish type) is homologous to gelsolin, an actin-binding protein.
Biochemical and biophysical research communications 1990;167(3):927-32.
1990: Ghiso J; Saball E; Leoni J; Rostagno A; Frangione B
Binding of cystatin C to C4: the importance of sense-antisense peptides in their interaction.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1288-91.
1990: Picken M M; Larrondo-Lillo M; Coria F; Gallo G R; Shelanski M L; Frangione B
Distribution of the protease inhibitor alpha 1-antichymotrypsin in cerebral and systemic amyloid.
Journal of neuropathology and experimental neurology 1990;49(1):41-8.
1989: Rostagno A A; Frangione B; Gold L I
Biochemical characterization of the fibronectin binding sites for IgG.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(10):3277-82.
1989: Verga L; Frangione B; Tagliavini F; Giaccone G; Migheli A; Bugiani O
Alzheimer patients and Down patients: cerebral preamyloid deposits differ ultrastructurally and histochemically from the amyloid of senile plaques.
Neuroscience letters 1989;105(3):294-9.
1989: Bugiani O; Giaccone G; Frangione B; Ghetti B; Tagliavini F
Alzheimer patients: preamyloid deposits are more widely distributed than senile plaques throughout the central nervous system.
Neuroscience letters 1989;103(3):263-8.
1989: Ghiso J; Tagliavini F; Timmers W F; Frangione B
Alzheimer's disease amyloid precursor protein is present in senile plaques and cerebrospinal fluid: immunohistochemical and biochemical characterization.
Biochemical and biophysical research communications 1989;163(1):430-7.
1989: Gallo G; Picken M; Buxbaum J; Frangione B
The spectrum of monoclonal immunoglobulin deposition disease associated with immunocytic dyscrasias.
Seminars in hematology 1989;26(3):234-45.
1989: Levy E; Lopez-Otin C; Ghiso J; Geltner D; Frangione B
Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases.
The Journal of experimental medicine 1989;169(5):1771-8.
1989: Gowda D C; Margolis R K; Frangione B; Ghiso J; Larrondo-Lillo M; Margolis R U
Relation of the amyloid beta protein precursor to heparan sulfate proteoglycans.
Science (New York, N.Y.) 1989;244(4906):826-8.
1989: Goñi F R; Chen P P; McGinnis D; Arjonilla M L; Fernandez J; Carson D; Solomon A; Mendez E; Frangione B
Structural and idiotypic characterization of the L chains of human IgM autoantibodies with different specificities.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(9):3158-63.
1989: Picken M M; Frangione B; Barlogie B; Luna M; Gallo G
Light chain deposition disease derived from the kappa I light chain subgroup. Biochemical characterization.
The American journal of pathology 1989;134(4):749-54.
1989: Gorevic P D; Prelli F C; Wright J; Pras M; Frangione B
Systemic senile amyloidosis. Identification of a new prealbumin (transthyretin) variant in cardiac tissue: immunologic and biochemical similarity to one form of familial amyloidotic polyneuropathy.
The Journal of clinical investigation 1989;83(3):836-43.
1989: Giaccone G; Tagliavini F; Linoli G; Bouras C; Frigerio L; Frangione B; Bugiani O
Down patients: extracellular preamyloid deposits precede neuritic degeneration and senile plaques.
Neuroscience letters 1989;97(1-2):232-8.
1989: Frangione B
Systemic and cerebral amyloidosis.
Annals of medicine 1989;21(2):69-72.
1989: Tagliavini F; Giaccone G; Linoli G; Frangione B; Bugiani O
Cerebral extracellular preamyloid deposits in Alzheimer's disease, Down syndrome and nondemented elderly individuals.
Progress in clinical and biological research 1989;317():1001-5.
1988: Silverman G J; Goñi F; Fernandez J; Chen P P; Frangione B; Carson D A
Distinct patterns of heavy chain variable region subgroup use by human monoclonal autoantibodies of different specificity.
The Journal of experimental medicine 1988;168(6):2361-6.
1988: Tagliavini F; Giaccone G; Frangione B; Bugiani O
Preamyloid deposits in the cerebral cortex of patients with Alzheimer's disease and nondemented individuals.
Neuroscience letters 1988;93(2-3):191-6.
1988: Gallo G; Picken M; Frangione B; Buxbaum J
Nonamyloidotic monoclonal immunoglobulin deposits lack amyloid P component.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1988;1(6):453-6.
1988: Coria F; Prelli F; Castaño E M; Larrondo-Lillo M; Fernandez-Gonzalez J; van Duinen S G; Bots G T; Luyendijk W; Shelanski M L; Frangione B
Beta-protein deposition: a pathogenetic link between Alzheimer's disease and cerebral amyloid angiopathies.
Brain research 1988;463(1):187-91.
1988: Prelli F; Castaño E; Glenner G G; Frangione B
Differences between vascular and plaque core amyloid in Alzheimer's disease.
Journal of neurochemistry 1988;51(2):648-51.
1988: Silverman G J; Goldfien R D; Chen P; Mageed R A; Jefferis R; Goñi F; Frangione B; Fong S; Carson D A
Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.
The Journal of clinical investigation 1988;82(2):469-75.
1988: Luyendijk W; Bots G T; Vegter-van der Vlis M; Went L N; Frangione B
Hereditary cerebral haemorrhage caused by cortical amyloid angiopathy.
Journal of the neurological sciences 1988;85(3):267-80.
1988: Ghiso J; Cowan N; Frangione B
Isolation of a sequence encoding human cystatin C. Conservation of exon-intron structure between members of the cysteine proteinase inhibitors superfamily.
Biological chemistry Hoppe-Seyler 1988;369 Suppl():205-8.
1988: Coria F; Castaño E; Prelli F; Larrondo-Lillo M; van Duinen S; Shelanski M L; Frangione B
Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis.
Laboratory investigation; a journal of technical methods and pathology 1988;58(4):454-8.
1988: Prelli F; Castaño E M; van Duinen S G; Bots G T; Luyendijk W; Frangione B
Different processing of Alzheimer's beta-protein precursor in the vessel wall of patients with hereditary cerebral hemorrhage with amyloidosis-Dutch type.
Biochemical and biophysical research communications 1988;151(3):1150-5.
1988: Castaño E M; Frangione B
Human amyloidosis, Alzheimer disease and related disorders.
Laboratory investigation; a journal of technical methods and pathology 1988;58(2):122-32.
1988: Mihaesco E; Gendron M C; Congy N; Frangione B
Protein Rou. A human IgA hybrid.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(4):1236-8.
1988: Goñi F; Chuba J; Buxbaum J; Frangione B
A double monoclonal IgG1 kappa and IgG2 kappa in a single myeloma patient. Variation in clonal products and therapeutic responses.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(2):551-7.
1988: Chen P P; Fong S; Goni F; Silverman G J; Fox R I; Liu M F; Frangione B; Carson D A
Cross-reacting idiotypes on cryoprecipitating rheumatoid factor.
Springer seminars in immunopathology 1988;10(1):35-55.
1987: Prelli F; Pras M; Frangione B
Degradation and deposition of amyloid AA fibrils are tissue specific.
Biochemistry 1987;26(25):8251-6.
1987: Picken M M; Pelton K; Frangione B; Gallo G
Primary amyloidosis A. Immunohistochemical and biochemical characterization.
The American journal of pathology 1987;129(3):536-42.
1987: Coria F; Castaño E M; Frangione B
Brain amyloid in normal aging and cerebral amyloid angiopathy is antigenically related to Alzheimer's disease beta-protein.
The American journal of pathology 1987;129(3):422-8.
1987: Warfel A H; Zucker-Franklin D; Frangione B; Ghiso J
Constitutive secretion of cystatin C (gamma-trace) by monocytes and macrophages and its downregulation after stimulation.
The Journal of experimental medicine 1987;166(6):1912-7.
1987: Ooi C E; Weiss J; Elsbach P; Frangione B; Mannion B
A 25-kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein.
The Journal of biological chemistry 1987;262(31):14891-4.
1987: Gorevic P D; Castano E M; Sarma R; Frangione B
Ten to fourteen residue peptides of Alzheimer's disease protein are sufficient for amyloid fibril formation and its characteristic x-ray diffraction pattern.
Biochemical and biophysical research communications 1987;147(2):854-62.
1987: van Duinen S G; Castaño E M; Prelli F; Bots G T; Luyendijk W; Frangione B
Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5991-4.
1987: Zucker-Franklin D; Warfel A; Grusky G; Frangione B; Teitel D
Novel monocyte-like properties of microglial/astroglial cells. Constitutive secretion of lysozyme and cystatin-C.
Laboratory investigation; a journal of technical methods and pathology 1987;57(2):176-85.
1987: Garcia-Pardo A; Rostagno A; Frangione B
Primary structure of human plasma fibronectin. Characterization of a 38 kDa domain containing the C-terminal heparin-binding site (Hep III site) and a region of molecular heterogeneity.
The Biochemical journal 1987;241(3):923-8.
1987: Goñi F R; Frangione B
Association between human IgM autoantibodies and kappa chain allotypes.
Journal of immunogenetics 1987;14(1):15-22.
1987: Agnello V; Goñi F; Barnes J L; de la Vega M T; Frangione B
Human rheumatoid factor crossidiotypes. II. Primary structure-dependent crossreactive idiotype, PSL2-CRI, present on Wa monoclonal rheumatoid factors is present on Bla and other IgM kappa monoclonal autoantibodies.
The Journal of experimental medicine 1987;165(1):263-7.
1987: Chen P P; Fong S; Goni F; Houghten R A; Frangione B; Liu F T; Carson D A
Analyses of human rheumatoid factors with anti-idiotypes induced by synthetic peptides.
Monographs in allergy 1987;22():12-23.
1986: Castaño E M; Ghiso J; Prelli F; Gorevic P D; Migheli A; Frangione B
In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease beta-protein.
Biochemical and biophysical research communications 1986;141(2):782-9.
1986: Gorevic P D; Goñi F; Pons-Estel B; Alvarez F; Peress N S; Frangione B
Isolation and partial characterization of neurofibrillary tangles and amyloid plaque core in Alzheimer's disease: immunohistological studies.
Journal of neuropathology and experimental neurology 1986;45(6):647-64.
1986: Rostagno A; Frangione B; Pearlstein E; Garcia-Pardo A
Fibronectin binds to amyloid P component. Localization of the binding site to the 31,000 dalton C-terminal domain.
Biochemical and biophysical research communications 1986;140(1):12-20.
1986: Gorevic P D; Munoz P C; Casey T T; DiRaimondo C R; Stone W J; Prelli F C; Rodrigues M M; Poulik M D; Frangione B
Polymerization of intact beta 2-microglobulin in tissue causes amyloidosis in patients on chronic hemodialysis.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(20):7908-12.
1986: Forst S; Weiss J; Blackburn P; Frangione B; Goni F; Elsbach P
Amino acid sequence of a basic Agkistrodon halys blomhoffii phospholipase A2. Possible role of NH2-terminal lysines in action on phospholipids of Escherichia coli.
Biochemistry 1986;25(15):4309-14.
1986: Picken M M; Gallo G; Buxbaum J; Frangione B
Characterization of renal amyloid derived from the variable region of the lambda light chain subgroup II.
The American journal of pathology 1986;124(1):82-7.
1986: Prelli F; Tummolo D; Solomon A; Frangione B
Novel human light chain V kappa segment: serologic and structural analyses of the kappa III-like Bence Jones protein and IgG kappa light chain REE.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(11):4169-73.
1986: Ghiso J; Jensson O; Frangione B
Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C).
Proceedings of the National Academy of Sciences of the United States of America 1986;83(9):2974-8.
1986: McGraw T; Mindich L; Frangione B
Nucleotide sequence of the small double-stranded RNA segment of bacteriophage phi 6: novel mechanism of natural translational control.
Journal of virology 1986;58(1):142-51.
1986: Ghiso J; Pons-Estel B; Frangione B
Hereditary cerebral amyloid angiopathy: the amyloid fibrils contain a protein which is a variant of cystatin C, an inhibitor of lysosomal cysteine proteases.
Biochemical and biophysical research communications 1986;136(2):548-54.
1986: Ghiso J; Solomon A; Frangione B
Association of human lambda light chain V/J/C segments: serologic analysis and primary structure of the lambda VI Bence Jones protein THO.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(2):716-9.
1985: Gorevic P D; Casey T T; Stone W J; DiRaimondo C R; Prelli F C; Frangione B
Beta-2 microglobulin is an amyloidogenic protein in man.
The Journal of clinical investigation 1985;76(6):2425-9.
1985: Goñi F; Chen P P; Pons-Estel B; Carson D A; Frangione B
Sequence similarities and cross-idiotypic specificity of L chains among human monoclonal IgM kappa with anti-gamma-globulin activity.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(6):4073-9.
1985: Pras M; Itzchaki M; Prelli F; Dollberg L; Frangione B
Amyloid arthropathy: characterization of the amyloid protein.
Clinical and experimental rheumatology 1985;3(4):327-31.
1985: Prelli F; Pras M; Frangione B
The primary structure of human tissue amyloid P component from a patient with primary idiopathic amyloidosis.
The Journal of biological chemistry 1985;260(24):12895-8.
1985: Chen P P; Gõni F; Houghten R A; Fong S; Goldfien R; Vaughan J H; Frangione B; Carson D A
Characterization of human rheumatoid factors with seven antiidiotypes induced by synthetic hypervariable region peptides.
The Journal of experimental medicine 1985;162(2):487-500.
1985: Naparstek Y; Duggan D; Schattner A; Madaio M P; Goni F; Frangione B; Stollar B D; Kabat E A; Schwartz R S
Immunochemical similarities between monoclonal antibacterial Waldenstrom's macroglobulins and monoclonal anti-DNA lupus autoantibodies.
The Journal of experimental medicine 1985;161(6):1525-38.
1985: Frangione B; Moloshok T; Prelli F; Solomon A
Human lambda light-chain constant region gene CMor lambda: the primary structure of lambda VI Bence Jones protein Mor.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(10):3415-9.
1985: Chen P P; Goñi F; Fong S; Jirik F; Vaughan J H; Frangione B; Carson D A
The majority of human monoclonal IgM rheumatoid factors express a "primary structure-dependent" cross-reactive idiotype.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(5):3281-5.
1985: Gorevic P D; Prelli F C; Frangione B
Immunoglobulin G (IgG).
Methods in enzymology 1985;116():3-25.
1984: Pons-Estel B; Goñi F; Solomon A; Frangione B
Sequence similarities among kappa IIIb chains of monoclonal human IgM kappa autoantibodies.
The Journal of experimental medicine 1984;160(3):893-904.
1984: Garcia-Pardo A; Pearlstein E; Frangione B
Primary structure of human plasma fibronectin--characterization of the 6,000 dalton C-terminal fragment containing the interchain disulfide bridges.
Biochemical and biophysical research communications 1984;120(3):1015-21.
1984: Putterman D G; Casadevall A; Boyle P D; Yang H L; Frangione B; Day L A
Major coat protein and single-stranded DNA-binding protein of filamentous virus Pf3.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(3):699-703.
1983: Frangione B; Moloshok T; Solomon A
Primary structure of the variable region of a human lambda VI light chain: Bence Jones protein SUT.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(5):2490-3.
1983: Ledford D K; Goñi F; Pizzolato M; Franklin E C; Solomon A; Frangione B
Preferential association of kappa IIIb light chains with monoclonal human IgM kappa autoantibodies.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(3):1322-5.
1983: Cohen D H; Feiner H; Jensson O; Frangione B
Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastroentero-pancreatic neuroendocrine protein, gamma trace.
The Journal of experimental medicine 1983;158(2):623-8.
1983: Menchel S; Cohen D; Gross E; Frangione B; Gallo G
AA protein-related renal amyloidosis in drug addicts.
The American journal of pathology 1983;112(2):195-9.
1983: Gold L I; Frangione B; Pearlstein E
Biochemical and immunological characterization of three binding sites on human plasma fibronectin with different affinities for heparin.
Biochemistry 1983;22(17):4113-9.
1983: Goñi F; Frangione B
Amino acid sequence of the Fv region of a human monoclonal IgM (protein WEA) with antibody activity against 3,4-pyruvylated galactose in Klebsiella polysaccharides K30 and K33.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(15):4837-41.
1983: Cohen D; Pras M; Franklin E C; Frangione B
Characterization of amyloid deposits and P component from a patient with factor X deficiency reveals proteins derived from a lambda VI light chain.
The American journal of medicine 1983;74(3):513-8.
1983: Pras M; Prelli F; Franklin E C; Frangione B
Primary structure of an amyloid prealbumin variant in familial polyneuropathy of Jewish origin.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(2):539-42.
1982: Pras M; Frangione B; Franklin E C; Gafni J
Idiopathic AL-kiv amyloidosis presenting as giant hepatomegaly.
Israel journal of medical sciences 1982;18(8):866-9.
1982: Solomon A; Frangione B; Franklin E C
Bence Jones proteins and light chains of immunoglobulins. Preferential association of the V lambda VI subgroup of human light chains with amyloidosis AL (lambda).
The Journal of clinical investigation 1982;70(2):453-60.
1982: Alexander A; Steinmetz M; Barritault D; Frangione B; Franklin E C; Hood L; Buxbaum J N
gamma Heavy chain disease in man: cDNA sequence supports partial gene deletion model.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(10):3260-4.
1982: Van Loghem E; Frangione B; Recht B; Franklin E C
Staphylococcal protein A and human IgG subclasses and allotypes.
Scandinavian journal of immunology 1982;15(3):275-8.
1982: Mendez E; Grubb A O; Lopez C; Frangione B; Franklin E C
Human complex-forming glycoprotein, heterogeneous in charge: the primary structure around the cysteine residues and characterization of a disulfide bridge.
Archives of biochemistry and biophysics 1982;213(1):240-50.
1981: Frangione B; Rosenwasser E; Penefsky H S; Pullman M E
Amino acid sequence of the protein inhibitor of mitochondrial adenosine triphosphatase.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(12):7403-7.
1981: Pras M; Franklin E C; Prelli F; Frangione B
A variant of prealbumin from amyloid fibrils in familial polyneuropathy of Jewish origin.
The Journal of experimental medicine 1981;154(3):989-93.
1979: Franklin E C; Prelli F; Frangione B
Human heavy chain disease protein WIS: implications for the organization of immunoglobulin genes.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(1):452-6.
1976: Wolfenstein-Todel C; Frangione B; Prelli F; Franklin E C
The amino acid sequence of "heavy chain disease" protein ZUC. Structure of the Fc fragment of immunoglobulin G3.
Biochemical and biophysical research communications 1976;71(4):907-14.
1976: Frangione B
A new immunoglobulin variant: gamma3 heavy chain disease protein CHI.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(5):1552-5.
1976: Franklin E C; Frangione B; Prelli F
The defect in mu heavy chain disease protein GLI.
Journal of immunology (Baltimore, Md. : 1950) 1976;116(4):1194-5.
1976: Frangione B; Franklin E C; Prelli F
Mu heavy-chain disease--a defect in immunoglobulin assembly. Structural studies of the kappa chain.
Scandinavian journal of immunology 1976;5(6-7):623-7.
1973: Mendez E; Prelli F; Frangione B; Franklin E C
Characterization of a disulfide bridge linking the J chain to the alpha chain of polymeric immunoglobulin A.
Biochemical and biophysical research communications 1973;55(4):1291-7.
1971: Franklin E C; Frangione B; Cooper S
Heavy chain diseases.
Annals of the New York Academy of Sciences 1971;190():457-66.
1971: Seligmann M; Mihaesco E; Frangione B
Alpha chain disease.
Annals of the New York Academy of Sciences 1971;190():487-500.
1971: Frangione B; Prelli F; Mihaesco C; Wolfenstein C; Mihaesco E; Franklin E C
Structural studies of immunoglobulin G, M and A heavy chains.
Annals of the New York Academy of Sciences 1971;190():71-82.
1971: Frangione B; Prelli F; Mihaesco C; Franklin E C
Interchain and intrachain disulfide bridges of a human immunoglobulin M: detection of a unique fragment.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(7):1547-51.
1971: Franklin E C; Frangione B
The molecular defect in a protein (CRA) found in gamma-1 heavy chain disease, and its genetic implications.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(1):187-91.
1964: MELTZER M; FRANKLIN E C; FUNDENBERG H; FRANGIONE B
SINGLE PEPTIDE DIFFERENCES BETWEEN GAMMA-GLOBULINS OF DIFFERENT GENETIC (GM) TYPES.
Proceedings of the National Academy of Sciences of the United States of America 1964;51():1007-14.

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