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Arthur Frankel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
25
Willingham, Mark
19
Hall, Philip
18
Tagge, Edward
14
Kreitman, Robert
12
Leppla, Stephen
10
Thorburn, Andrew
10
Hogge, Donna
9
Cohen, Kimberley
9
Liu, Tie Fu
9
Ramage, Jason
8
Burbage, C
8
Duesbery, Nicholas
7
Powell, Bayard
6
Abi-Habib, Ralph
6
Liu, Shihui

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Publications

TOP 3
Horita Henrick; Thorburn Jacqueline; Frankel Arthur E; Thorburn Andrew
EGFR-targeted diphtheria toxin stimulates TRAIL killing of glioblastoma cells by depleting anti-apoptotic proteins.
Thorburn Jacqueline; Frankel Arthur E; Thorburn Andrew
Regulation of HMGB1 release by autophagy.
Kuo Shu-Ru; Willingham Mark C; Bour Sarah H; Andreas Elissa A; Park Seong Kyu; Jackson Carney; Duesbery Nicholas S; Leppla Stephen H; Tang Wei-Jen; Frankel Arthur E
Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage.

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All Publications

2009: Horita Henrick; Thorburn Jacqueline; Frankel Arthur E; Thorburn Andrew
EGFR-targeted diphtheria toxin stimulates TRAIL killing of glioblastoma cells by depleting anti-apoptotic proteins.
Journal of neuro-oncology 2009;95(2):175-84.
2009: Thorburn Jacqueline; Frankel Arthur E; Thorburn Andrew
Regulation of HMGB1 release by autophagy.
Autophagy 2009;5(2):247-9.
2008: Kuo Shu-Ru; Willingham Mark C; Bour Sarah H; Andreas Elissa A; Park Seong Kyu; Jackson Carney; Duesbery Nicholas S; Leppla Stephen H; Tang Wei-Jen; Frankel Arthur E
Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage.
Microbial pathogenesis 2008;44(6):467-72.
2008: Ding Yan; Boguslawski Elissa A; Berghuis Bree D; Young John J; Zhang Zhongfa; Hardy Kim; Furge Kyle; Kort Eric; Frankel Arthur E; Hay Rick V; Resau James H; Duesbery Nicholas S
Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma.
Molecular cancer therapeutics 2008;7(3):648-58.
2008: Alfano Randall W; Leppla Stephen H; Liu Shihui; Bugge Thomas H; Duesbery Nicholas S; Frankel Arthur E
Potent inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin: implications for broad anti-tumor efficacy.
Cell cycle (Georgetown, Tex.) 2008;7(6):745-9.
2007: Depeille Philippe; Young John J; Boguslawski Elissa A; Berghuis Bree D; Kort Eric J; Resau James H; Frankel Arthur E; Duesbery Nicholas S
Anthrax lethal toxin inhibits growth of and vascular endothelial growth factor release from endothelial cells expressing the human herpes virus 8 viral G protein coupled receptor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(19):5926-34.
2007: Singh Ravibhushan; Browning Jeff L; Abi-Habib Ralph; Wong Kevin; Williams Simon A; Merchant Rosemina; Denmeade Samuel R; Buckley Thomas J; Frankel Arthur E
Recombinant prostate-specific antigen proaerolysin shows selective protease sensitivity and cell cytotoxicity.
Anti-cancer drugs 2007;18(7):809-16.
2007: Su Yunpeng; Ortiz Janelle; Liu Shihui; Bugge Thomas H; Singh Ravibhushan; Leppla Stephen H; Frankel Arthur E
Systematic urokinase-activated anthrax toxin therapy produces regressions of subcutaneous human non-small cell lung tumor in athymic nude mice.
Cancer research 2007;67(7):3329-36.
2006: Abi-Habib Ralph J; Singh Ravibhushan; Leppla Stephen H; Greene John J; Ding Yan; Berghuis Bree; Duesbery Nicholas S; Frankel Arthur E
Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7437-43.
2006: Yalcintepe Leman; Frankel Arthur E; Hogge Donna E
Expression of interleukin-3 receptor subunits on defined subpopulations of acute myeloid leukemia blasts predicts the cytotoxicity of diphtheria toxin interleukin-3 fusion protein against malignant progenitors that engraft in immunodeficient mice.
Blood 2006;108(10):3530-7.
2006: Abi-Habib Ralph J; Singh Ravibhushan; Liu Shihui; Bugge Thomas H; Leppla Stephen H; Frankel Arthur E
A urokinase-activated recombinant anthrax toxin is selectively cytotoxic to many human tumor cell types.
Molecular cancer therapeutics 2006;5(10):2556-62.
2006: Hall Philip D; Sinha Debajyoti; Frankel Arthur E
Fresh frozen plasma and platelet concentrates may increase plasma anti-diphtheria toxin IgG concentrations: Implications for diphtheria fusion protein therapy.
Cancer immunology, immunotherapy : CII 2006;55(8):928-32.
2006: Frankel Arthur E; Surendranathan Asha; Black Jennifer H; White Angela; Ganjoo Kristen; Cripe Larry D
Phase II clinical studies of denileukin diftitox diphtheria toxin fusion protein in patients with previously treated chronic lymphocytic leukemia.
Cancer 2006;106(10):2158-64.
2006: Thorburn Andrew; Frankel Arthur E
Apoptosis and anthracycline cardiotoxicity.
Molecular cancer therapeutics 2006;5(2):197-9.
2006: Hogge Donna E; Yalcintepe Leman; Wong Siaw-Hui; Gerhard Brigitte; Frankel Arthur E
Variant diphtheria toxin-interleukin-3 fusion proteins with increased receptor affinity have enhanced cytotoxicity against acute myeloid leukemia progenitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(4):1284-91.
2005: Abi-Habib Ralph J; Urieto Jeffrey O; Liu Shihui; Leppla Stephen H; Duesbery Nicholas S; Frankel Arthur E
BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin.
Molecular cancer therapeutics 2005;4(9):1303-10.
2005: Cohen Kimberley A; Liu Tie Fu; Cline J Mark; Wagner Janice D; Hall Philip D; Frankel Arthur E
Safety evaluation of DT388IL3, a diphtheria toxin/interleukin 3 fusion protein, in the cynomolgus monkey.
Cancer immunology, immunotherapy : CII 2005;54(8):799-806.
2005: Liu Tie Fu; Hall Philip D; Cohen Kimberley A; Willingham Mark C; Cai Jiaozhong; Thorburn Andrew; Frankel Arthur E
Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of subcutaneous human glioblastoma multiforme tumors in athymic nude mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(1):329-34.
2004: Westcott Marlena M; Abi-Habib Ralph J; Cohen Kimberley A; Willingham Mark C; Liu Shihui; Bugge Thomas H; Leppla Stephen H; Frankel Arthur E
Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor-induced hepatotoxicity is mediated by Kupffer cells.
Molecular cancer therapeutics 2004;3(12):1681-9.
2004: Hogge Donna E; Feuring-Buske Michaela; Gerhard Brigitte; Frankel Arthur E
The efficacy of diphtheria-growth factor fusion proteins is enhanced by co-administration of cytosine arabinoside in an immunodeficient mouse model of human acute myeloid leukemia.
Leukemia research 2004;28(11):1221-6.
2004: Abi-Habib Ralph J; Liu Shihui; Bugge Thomas H; Leppla Stephen H; Frankel Arthur E
A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia blasts.
Blood 2004;104(7):2143-8.
2004: Cohen Kimberley A; Liu Tie Fu; Cline J Mark; Wagner Janice D; Hall Philip D; Frankel Arthur E
Toxicology and pharmacokinetics of DT388IL3, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human interleukin 3 (IL3), in cynomolgus monkeys.
Leukemia & lymphoma 2004;45(8):1647-56.
2004: Liu Tie Fu; Urieto Jeffrey O; Moore Joseph E; Miller Mark S; Lowe A Corinne; Thorburn Andrew; Frankel Arthur E
Diphtheria toxin fused to variant interleukin-3 provides enhanced binding to the interleukin-3 receptor and more potent leukemia cell cytotoxicity.
Experimental hematology 2004;32(3):277-81.
2004: Thorburn A; Thorburn J; Frankel A E
Induction of apoptosis by tumor cell-targeted toxins.
Apoptosis : an international journal on programmed cell death 2004;9(1):19-25.
2004: Frankel Arthur E
Reducing the immune response to immunotoxin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(1 Pt 1):13-5.
2004: Urieto Jeffrey O; Liu TieFu; Black Jennifer H; Cohen Kimberley A; Hall Philip D; Willingham Mark C; Pennell Lewis K; Hogge Donna E; Kreitman Robert J; Frankel Arthur E
Expression and purification of the recombinant diphtheria fusion toxin DT388IL3 for phase I clinical trials.
Protein expression and purification 2004;33(1):123-33.
2003: Liu Tie Fu; Willingham Mark C; Tatter Stephen B; Cohen Kimberley A; Lowe A Corinne; Thorburn Andrew; Frankel Arthur E
Diphtheria toxin-epidermal growth factor fusion protein and Pseudomonas exotoxin-interleukin 13 fusion protein exert synergistic toxicity against human glioblastoma multiforme cells.
Bioconjugate chemistry 2003;14(6):1107-14.
2003: Liu Tie Fu; Cohen Kimberly A; Willingham Mark C; Tatter Stephen B; Puri Raj K; Frankel Arthur E
Combination fusion protein therapy of refractory brain tumors: demonstration of efficacy in cell culture.
Journal of neuro-oncology 2003;65(1):77-85.
2003: Mishra Girish; Liu Tie Fu; Frankel Arthur E
Recombinant toxin DAB389EGF is cytotoxic to human pancreatic cancer cells.
Expert opinion on biological therapy 2003;3(7):1173-80.
2003: Frankel Arthur E; Fleming Donald R; Hall Philip D; Powell Bayard L; Black Jennifer H; Leftwich Carole; Gartenhaus Ronald
A phase II study of DT fusion protein denileukin diftitox in patients with fludarabine-refractory chronic lymphocytic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 1):3555-61.
2003: Frankel Arthur E; Neville David M; Bugge Thomas A; Kreitman Robert J; Leppla Stephen H
Immunotoxin therapy of hematologic malignancies.
Seminars in oncology 2003;30(4):545-57.
2003: Liu Tie Fu; Tatter Stephen B; Willingham Mark C; Yang Mitchell; Hu Jennifer J; Frankel Arthur E
Growth factor receptor expression varies among high-grade gliomas and normal brain: epidermal growth factor receptor has excellent properties for interstitial fusion protein therapy.
Molecular cancer therapeutics 2003;2(8):783-7.
2003: Liu Tie Fu; Cohen Kimberley A; Ramage Jason G; Willingham Mark C; Thorburn Andrew M; Frankel Arthur E
A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells.
Cancer research 2003;63(8):1834-7.
2003: Frankel Arthur E; Fleming Donald R; Powell Bayard L; Gartenhaus Ronald
DAB389IL2 (ONTAK) fusion protein therapy of chronic lymphocytic leukaemia.
Expert opinion on biological therapy 2003;3(1):179-86.
2003: Thorburn Jacqueline; Frankel Arthur E; Thorburn Andrew
Apoptosis by leukemia cell-targeted diphtheria toxin occurs via receptor-independent activation of Fas-associated death domain protein.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):861-5.
2003: Cohen Kimberley A; Liu TieFu; Bissonette Reid; Puri Raj K; Frankel Arthur E
DAB389EGF fusion protein therapy of refractory glioblastoma multiforme.
Current pharmaceutical biotechnology 2003;4(1):39-49.
2003: Black J H; McCubrey J A; Willingham M C; Ramage J; Hogge D E; Frankel A E
Diphtheria toxin-interleukin-3 fusion protein (DT(388)IL3) prolongs disease-free survival of leukemic immunocompromised mice.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(1):155-9.
2003: Ramage Jason G; Vallera Daniel A; Black Jennifer H; Aplan Peter D; Kees Ursula R; Frankel Arthur E
The diphtheria toxin/urokinase fusion protein (DTAT) is selectively toxic to CD87 expressing leukemic cells.
Leukemia research 2003;27(1):79-84.
2003: Frankel Arthur E; Koo Han-Mo; Leppla Stephen H; Duesbery Nicholas S; Vande Woude George F
Novel protein targeted therapy of metastatic melanoma.
Current pharmaceutical design 2003;9(25):2060-6.
2002: Frankel Arthur E; Beran Miloslav; Hogge Donna E; Powell Bayard L; Thorburn Andrew; Chen Yong Q; Vallera Daniel A
Malignant progenitors from patients with CD87+ acute myelogenous leukemia are sensitive to a diphtheria toxin-urokinase fusion protein.
Experimental hematology 2002;30(11):1316-23.
2002: Hall Philip D; Razzouk Bassem I; Willoughby Tony E; McLean Thomas W; Frankel Arthur E
The majority of children and adolescents with acute myeloid leukemia have detectable anti-DT388-GMCSF IgG concentrations, but at concentrations that should not preclude in vivo activity.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 2002;24(7):521-6.
2002: Frankel Arthur E; Powell Bayard L; Duesbery Nick S; Vande Woude George F; Leppla Stephen H
Anthrax fusion protein therapy of cancer.
Current protein & peptide science 2002;3(4):399-407.
2002: Frankel Arthur E
New HER2-directed therapies for breast cancer. Commentary re: C. I. Spiridon et al., Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity. Clin. Cancer Res., 8: 1720-1730, 2002.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1699-701.
2002: Frankel Arthur E; Powell Bayard L; Hall Philip D; Case L Douglas; Kreitman Robert J
Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(5):1004-13.
2002: Frankel Arthur E; Rossi Patrick; Kuzel Timothy M; Foss Francine
Diphtheria fusion protein therapy of chemoresistant malignancies.
Current cancer drug targets 2002;2(1):19-36.
2002: Feuring-Buske Michaela; Frankel Arthur E; Alexander Richard L; Gerhard Brigitte; Hogge Donna E
A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.
Cancer research 2002;62(6):1730-6.
2002: Thomas Patrick B; Delatte Stephen J; Sutphin Aimee; Frankel Arthur E; Tagge Edward P
Effective targeted cytotoxicity of neuroblastoma cells.
Journal of pediatric surgery 2002;37(3):539-44.
2002: Frankel Arthur E; Bugge Thomas H; Liu Shihui; Vallera Daniel A; Leppla Stephen H
Peptide toxins directed at the matrix dissolution systems of cancer cells.
Protein and peptide letters 2002;9(1):1-14.
2002: Frankel Arthur E; Powell Bayard L; Lilly Michael B
Diphtheria toxin conjugate therapy of cancer.
Cancer chemotherapy and biological response modifiers 2002;20():301-13.
2001: Alexander R L; Ramage J; Kucera G L; Caligiuri M A; Frankel A E
High affinity interleukin-3 receptor expression on blasts from patients with acute myelogenous leukemia correlates with cytotoxicity of a diphtheria toxin/IL-3 fusion protein.
Leukemia research 2001;25(10):875-81.
2001: Frankel A E; Powell B L; Vallera D A; Neville D M
Chimeric fusion proteins--diphtheria toxin-based.
Current opinion in investigational drugs (London, England : 2000) 2001;2(9):1294-301.
2001: Frankel A E; Baer M R; Hogge D E; Stuart R K
Immunotherapy of acute myeloid leukemia.
Current pharmaceutical biotechnology 2001;2(3):209-15.
2001: Hall P D; Virella G; Willoughby T; Atchley D H; Kreitman R J; Frankel A E
Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia.
Clinical immunology (Orlando, Fla.) 2001;100(2):191-7.
2001: Kiser M; McCubrey J A; Steelman L S; Shelton J G; Ramage J; Alexander R L; Kucera G L; Pettenati M; Willingham M C; Miller M S; Frankel A E
Oncogene-dependent engraftment of human myeloid leukemia cells in immunosuppressed mice.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(5):814-8.
2000: Frankel A E; Sievers E L; Scheinberg D A
Cell surface receptor-targeted therapy of acute myeloid leukemia: a review.
Cancer biotherapy & radiopharmaceuticals 2000;15(5):459-76.
2000: Frankel A E; Ramage J; Kiser M; Alexander R; Kucera G; Miller M S
Characterization of diphtheria fusion proteins targeted to the human interleukin-3 receptor.
Protein engineering 2000;13(8):575-81.
2000: Alexander R L; Kucera G L; Klein B; Frankel A E
In vitro interleukin-3 binding to leukemia cells predicts cytotoxicity of a diphtheria toxin/IL-3 fusion protein.
Bioconjugate chemistry 2000;11(4):564-8.
2000: Frankel A E; McCubrey J A; Miller M S; Delatte S; Ramage J; Kiser M; Kucera G L; Alexander R L; Beran M; Tagge E P; Kreitman R J; Hogge D E
Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(4):576-85.
2000: Frankel A E; Kreitman R J; Sausville E A
Targeted toxins.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(2):326-34.
1999: Hotchkiss C E; Hall P D; Cline J M; Willingham M C; Kreitman R J; Gardin J; Latimer A; Ramage J; Feely T; DeLatte S; Tagge E P; Frankel A E
Toxicology and pharmacokinetics of DTGM, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor, in cynomolgus monkeys.
Toxicology and applied pharmacology 1999;158(2):152-60.
1999: Kim C N; Bhalla K; Kreitman R J; Willingham M C; Hall P; Tagge E P; Jia T; Frankel A E
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor and Ara-C exert synergistic toxicity against human AML HL-60 cells.
Leukemia research 1999;23(6):527-38.
1999: Frankel A E; Ramage J; Latimer A; Feely T; Delatte S; Hall P; Tagge E; Kreitman R; Willingham M
High-level expression and purification of the recombinant diphtheria fusion toxin DTGM for PHASE I clinical trials.
Protein expression and purification 1999;16(1):190-201.
1999: Hall P D; Willingham M C; Kreitman R J; Frankel A E
DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(4):629-33.
1998: Frankel A E; Lilly M; Kreitman R; Hogge D; Beran M; Freedman M H; Emanuel P D; McLain C; Hall P; Tagge E; Berger M; Eaves C
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
Blood 1998;92(11):4279-86.
1998: Frankel A E; Hall P D; McLain C; Safa A R; Tagge E P; Kreitman R J
Cell-specific modulation of drug resistance in acute myeloid leukemic blasts by diphtheria fusion toxin, DT388-GMCSF.
Bioconjugate chemistry 1998;9(4):490-6.
1998: Hogge D E; Willman C L; Kreitman R J; Berger M; Hall P D; Kopecky K J; McLain C; Tagge E P; Eaves C J; Frankel A E
Malignant progenitors from patients with acute myelogenous leukemia are sensitive to a diphtheria toxin-granulocyte-macrophage colony-stimulating factor fusion protein.
Blood 1998;92(2):589-95.
1998: Hall P D; Kreitman R J; Willingham M C; Frankel A E
Toxicology and pharmacokinetics of DT388-GM-CSF, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) in C57BL/6 mice.
Toxicology and applied pharmacology 1998;150(1):91-7.
1997: Frankel A E; Hall P D; Burbage C; Vesely J; Willingham M; Bhalla K; Kreitman R J
Modulation of the apoptotic response of human myeloid leukemia cells to a diphtheria toxin granulocyte-macrophage colony-stimulating factor fusion protein.
Blood 1997;90(9):3654-61.
1997: Frankel A E; Laver J H; Willingham M C; Burns L J; Kersey J H; Vallera D A
Therapy of patients with T-cell lymphomas and leukemias using an anti-CD7 monoclonal antibody-ricin A chain immunotoxin.
Leukemia & lymphoma 1997;26(3-4):287-98.
1997: Burbage C; Tagge E P; Harris B; Hall P; Fu T; Willingham M C; Frankel A E
Ricin fusion toxin targeted to the human granulocyte-macrophage colony stimulating factor receptor is selectively toxic to acute myeloid leukemia cells.
Leukemia research 1997;21(7):681-90.
1997: Frankel A E; Fu T; Burbage C; Tagge E; Harris B; Vesely J; Willingham M C
Lectin-deficient ricin toxin intoxicates cells bearing the D-mannose receptor.
Carbohydrate research 1997;300(3):251-8.
1997: Frankel A E; Fu T; Burbage C; Chandler J; Willingham M C; Tagge E P
IL2 fused to lectin-deficient ricin is toxic to human leukemia cells expressing the IL2 receptor.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(1):22-30.
1996: Fu T; Burbage C; Tagge E P; Brothers T; Willingham M C; Frankel A E
Ricin toxin contains three lectin sites which contribute to its in vivo toxicity.
International journal of immunopharmacology 1996;18(12):685-92.
1996: Frankel A E; Burbage C; Fu T; Tagge E; Chandler J; Willingham M C
Ricin toxin contains at least three galactose-binding sites located in B chain subdomains 1 alpha, 1 beta, and 2 gamma.
Biochemistry 1996;35(47):14749-56.
1996: Frankel A E; Burbage C; Fu T; Tagge E; Chandler J; Willingham M
Characterization of a ricin fusion toxin targeted to the interleukin-2 receptor.
Protein engineering 1996;9(10):913-9.
1996: Vallera D A; Burns L J; Frankel A E; Sicheneder A R; Gunther R; Gajl-Peczalska K; Pennell C A; Kersey J H
Laboratory preparation of a deglycosylated ricin toxin A chain containing immunotoxin directed against a CD7 T lineage differentiation antigen for phase I human clinical studies involving T cell malignancies.
Journal of immunological methods 1996;197(1-2):69-83.
1996: Chandler J C; Frankel A E; Tagge E P
Genetic engineering of immunotoxins.
Seminars in pediatric surgery 1996;5(3):206-11.
1996: Tagge E P; Tagge D U; Chandler J C; Pitre B R; Haddad G; Frankel A E; Willingham M C; Garvin A J; Papas T S
Molecular biology and the pediatric surgeon: definitions and basic methodology.
Seminars in pediatric surgery 1996;5(3):139-48.
1996: Tagge E P; Chandler J; Harris B; Czako M; Marton L; Willingham M C; Burbage C; Afrin L; Frankel A E
Preproricin expressed in Nicotiana tabacum cells in vitro is fully processed and biologically active.
Protein expression and purification 1996;8(1):109-18.
1996: Re G G; Waters C; Poisson L; Willingham M C; Sugamura K; Frankel A E
Interleukin 2 (IL-2) receptor expression and sensitivity to diphteria fusion toxin DAB389IL-2 in cultured hematopoietic cells.
Cancer research 1996;56(11):2590-5.
1996: Frankel A E; FitzGerald D; Siegall C; Press O W
Advances in immunotoxin biology and therapy: a summary of the Fourth International Symposium on Immunotoxins.
Cancer research 1996;56(4):926-32.
1995: Frankel A E; Tagge E P; Willingham M C
Clinical trials of targeted toxins.
Seminars in cancer biology 1995;6(5):307-17.
1994: Afrin L B; Gulick H; Vesely J; Willingham M; Frankel A E
Expression of oligohistidine-tagged ricin B chain in Spodoptera frugiperda.
Bioconjugate chemistry 1994;5(6):539-46.

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