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Jayne Franklyn

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Disorders

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Thyroid Gland

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TOP 3
Kristien Boelaert; Patrick Maisonneuve; Barbara Torlinska; Jayne A Franklyn
Comparison of mortality in hyperthyroidism during periods of treatment with thionamides and after radioiodine.
Ken K Ong; Mary Pierce; Jayne A Franklyn; Diana Kuh
Childhood weight gain and thyroid autoimmunity at age 60-64 years: the 1946 British birth cohort study.
Jonathan M Hazlehurst; Michael W O'Reilly; Ian A Rowe; Mark Sherlock; Paul M Stewart; Matthew J Armstrong; Jayne A Franklyn; Jeremy W Tomlinson
A comparative quality assessment of evidence-based clinical guidelines in endocrinology.

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All Publications

2013: Kristien Boelaert; Patrick Maisonneuve; Barbara Torlinska; Jayne A Franklyn
Comparison of mortality in hyperthyroidism during periods of treatment with thionamides and after radioiodine.
The Journal of clinical endocrinology and metabolism 2013;98(5):1869-82.
2013: Ken K Ong; Mary Pierce; Jayne A Franklyn; Diana Kuh
Childhood weight gain and thyroid autoimmunity at age 60-64 years: the 1946 British birth cohort study.
The Journal of clinical endocrinology and metabolism 2013;98(4):1435-42.
2013: Jonathan M Hazlehurst; Michael W O'Reilly; Ian A Rowe; Mark Sherlock; Paul M Stewart; Matthew J Armstrong; Jayne A Franklyn; Jeremy W Tomlinson
A comparative quality assessment of evidence-based clinical guidelines in endocrinology.
Clinical endocrinology 2013;78(2):183-90.
2013: Jayne A Franklyn
The thyroid--too much and too little across the ages. The consequences of subclinical thyroid dysfunction.
Clinical endocrinology 2013;78(1):1-8.
2012: L S Loubière; P M Taylor; E Vasilopoulou; Jayne A Franklyn; J D Glazier; Mark D Kilby; Shiao Y Chan
Expression and function of thyroid hormone transporters in the microvillous plasma membrane of human term placental syncytiotrophoblast.
Endocrinology 2012;153(12):6126-35.
2012: Jason D Cooper; Jayne A Franklyn; Oliver J Brand; Oliver Burren; Gillian Coleman; Hui Guo; Matthew J Simmonds; Helen Stevens; John A Todd; Neil M Walker; Chris Wallace; Stephen C L Gough
Seven newly identified loci for autoimmune thyroid disease.
Human molecular genetics 2012;21(23):5202-8.
2012: Penny M Clark; Sayeed M Haque; F D Richard Hobbs; Roger L Holder; Lesley M Roberts; Jayne A Franklyn
The relationship between serum TSH and free T4 in older people.
Postgraduate medical journal 2012;88(1045):668-70.
2012: V E Smith; Andrew S Turnell; H Mehanna; Martin L Read; G Ryan; R I Seed; N Sharma; Kristien Boelaert; S Y Chan; V M Darras; J C W Fong; Jayne A Franklyn; P Kwan; G D Lewy; Chris J McCabe
PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8.
Endocrinology 2012;153(7):3526-36.
2012: Tinh-Hai Collet; Jacques Cornuz; Wendy P J den Elzen; Jayne A Franklyn; Bariş Gencer; Jacobijn Gussekloo; Giorgio Iervasi; Kay-Tee Khaw; Robert N Luben; Rui M B Maciel; Patrick Maisonneuve; Sabrina Molinaro; Anne B Newman; Nicolas Rodondi; José A Sgarbi; Eric Vittinghoff; Henry Völzke; John P Walsh; Rudi G J Westendorp; Bjørn O Asvold; Philippe Balmer; Douglas Charles Bauer; Alexandra Bremner; Anne R Cappola
Subclinical hyperthyroidism and the risk of coronary heart disease and mortality.
Archives of internal medicine 2012;172(10):799-809.
2012: Ujjal Mallick; Ralph McCready; Laura Moss; Kate Newbold; Alice Nicol; Christopher M Nutting; Tom Roques; James Smellie; Rengarajan Vijayan; Jonathan Wadsley; Stephen Whitaker; Beng Yap; Abdel Abdel-Hamid; Pablo Alvarez; Sandy Beare; Penelope M Clark; Susan Clarke; Kate Farnell; Sharon Forsyth; Jayne A Franklyn; Georgina Gerrard; John Hardman; Clive Harmer; Rhys John; Latha Kadalayil; Catherine Lemon; Elena Macias; Allan Hackshaw
Ablation with low-dose radioiodine and thyrotropin alfa in thyroid cancer.
The New England journal of medicine 2012;366(18):1674-85.
2012: Penny M Clark; Sayeed M Haque; F D Richard Hobbs; Roger L Holder; Lesley M Roberts; Jayne A Franklyn
The relationship between serum TSH and free T4 in older people.
Journal of clinical pathology 2012;65(5):463-5.
2012: Jayne A Franklyn; Kristien Boelaert
Thyrotoxicosis.
Lancet 2012;379(9821):1155-66.
2011: Martin L Read; Robert I Seed; Neil Sharma; Vicki E Smith; Adrian Warfield; John C Watkinson; Kristien Boelaert; Sundaram Ramasamy; Jim C W Fong; Jayne A Franklyn; Erica Gentilin; Jeffrey A Knauf; Wendy E Leadbeater; Greg D Lewy; Christopher J McCabe
Proto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatment.
Cancer research 2011;71(19):6153-64.
2011: Mark P J Vanderpump; Kristien Boelaert; Jayne A Franklyn; Roger L Holder; Peter Laurberg; John H Lazarus; Peter P Smyth
Iodine status of UK schoolgirls: a cross-sectional survey.
Lancet 2011;377(9782):2007-12.
2011: S-Y Chan; A Martín-Santos; L S Loubière; A M González; B Stieger; A Logan; Chris J McCabe; Jayne A Franklyn; Mark D Kilby
The expression of thyroid hormone transporters in the human fetal cerebral cortex during early development and in N-Tera-2 neurodifferentiation.
The Journal of physiology 2011;589(Pt 11):2827-45.
2010: Matthew J Simmonds; Oliver J Brand; Jeffrey C Barrett; Paul R Newby; Jayne A Franklyn; S C L Gough
Association of Fc receptor-like 5 (FCRL5) with Graves' disease is secondary to the effect of FCRL3.
Clinical endocrinology 2010;73(5):654-60.
2010: E Vasilopoulou; L S Loubière; A Martín-Santos; Chris J McCabe; Jayne A Franklyn; Mark D Kilby; S-Y Chan
Differential triiodothyronine responsiveness and transport by human cytotrophoblasts from normal and growth-restricted pregnancies.
The Journal of clinical endocrinology and metabolism 2010;95(10):4762-70.
2010: Nicolas Rodondi; Wendy P J den Elzen; Douglas Charles Bauer; Anne R Cappola; Salman Razvi; John P Walsh; Bjørn O Asvold; Giorgio Iervasi; Misa Imaizumi; Tinh-Hai Collet; Alexandra Bremner; Patrick Maisonneuve; José A Sgarbi; Kay-Tee Khaw; Mark P J Vanderpump; Anne B Newman; Jacques Cornuz; Jayne A Franklyn; Rudi G J Westendorp; Eric Vittinghoff; Jacobijn Gussekloo
Subclinical hypothyroidism and the risk of coronary heart disease and mortality.
JAMA : the journal of the American Medical Association 2010;304(12):1365-74.
2010: Paul R Newby; Oliver J Pickles; Samaresh Mazumdar; Oliver J Brand; Jackie Carr-Smith; Simon H S Pearce; Jayne A Franklyn; David M Evans; Matthew J Simmonds; S C L Gough
Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study.
European journal of human genetics : EJHG 2010;18(9):1021-6.
2010: James V Parle; Lesley Roberts; S Wilson; Helen Pattison; Andrea Roalfe; M Sayeed Haque; C Heath; M Sheppard; Jayne A Franklyn; F D Richard Hobbs
A randomized controlled trial of the effect of thyroxine replacement on cognitive function in community-living elderly subjects with subclinical hypothyroidism: the Birmingham Elderly Thyroid study.
The Journal of clinical endocrinology and metabolism 2010;95(8):3623-32.
2010: Kadija Yesmin; Chantal Hargreaves; Paul R Newby; Oliver J Brand; Joanne M Heward; Jayne A Franklyn; S C L Gough; Matthew J Simmonds
Association of FcGRIIa with Graves' disease: a potential role for dysregulated autoantibody clearance in disease onset/progression.
Clinical endocrinology 2010;73(1):119-25.
2010: Kristien Boelaert; B Torlinska; Roger L Holder; Jayne A Franklyn
Older subjects with hyperthyroidism present with a paucity of symptoms and signs: a large cross-sectional study.
The Journal of clinical endocrinology and metabolism 2010;95(6):2715-26.
2010: Rachel J Watkins; Martin L Read; Vicki E Smith; Neil Sharma; Gary M Reynolds; Laura Buckley; Craig Doig; Moray J Campbell; Greg Lewy; Sundaram Ramasamy; Laurence S Loubiere; Jayne A Franklyn; Kristien Boelaert; Christopher J McCabe
Pituitary tumor transforming gene binding factor: a new gene in breast cancer.
Cancer research 2010;70(9):3739-49.
2010: Matthew J Simmonds; Kadija Yesmin; Paul R Newby; Oliver J Brand; Jayne A Franklyn; S C L Gough
Confirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease.
Thyroid : official journal of the American Thyroid Association 2010;20(4):413-7.
2010: L S Loubière; E Vasilopoulou; Judith N Bulmer; P M Taylor; B Stieger; F Verrey; Chris J McCabe; Jayne A Franklyn; Mark D Kilby; S-Y Chan
Expression of thyroid hormone transporters in the human placenta and changes associated with intrauterine growth restriction.
Placenta 2010;31(4):295-304.
2010: Sally R James; Aaron M Ranasinghe; Rajamiyer Venkateswaran; Christopher J McCabe; Jayne A Franklyn; Robert S Bonser
The effects of acute triiodothyronine therapy on myocardial gene expression in brain stem dead cardiac donors.
The Journal of clinical endocrinology and metabolism 2010;95(3):1338-43.
2010: Kristien Boelaert; Paul R Newby; Matthew J Simmonds; Roger L Holder; Jackie Carr-Smith; Joanne M Heward; Nilusha Manji; Amit Allahabadia; M Armitage; Krishna V Chatterjee; John H Lazarus; Simon H S Pearce; Bijay Vaidya; S C L Gough; Jayne A Franklyn
Prevalence and relative risk of other autoimmune diseases in subjects with autoimmune thyroid disease.
The American journal of medicine 2010;123(2):183.e1-9.
2010: Vicki E Smith; Jayne A Franklyn; Christopher J McCabe
Pituitary tumor-transforming gene and its binding factor in endocrine cancer.
Expert reviews in molecular medicine 2010;12():e38.
2010: Rafał Płoski; Oliver J Brand; Beata Jurecka-Lubieniecka; Maria Franaszczyk; Dorota Kula; Pawel Krajewski; Muhammad A Karamat; Matthew J Simmonds; Jayne A Franklyn; Stephen C L Gough; Barbara Jarząb; Tomasz Bednarczuk
Thyroid stimulating hormone receptor (TSHR) intron 1 variants are major risk factors for Graves' disease in three European Caucasian cohorts.
PloS one 2010;5(11):e15512.
2010: Jayne A Franklyn
What is the role of radioiodine uptake measurement and thyroid scintigraphy in the diagnosis and management of hyperthyroidism?
Clinical endocrinology 2010;72(1):11-2.
2009: Jayne A Franklyn
Thyroid gland: Antithyroid therapy--best choice of drug and dose.
Nature reviews. Endocrinology 2009;5(11):592-4.
2009: Vicki E Smith; Martin L Read; Andrew S Turnell; Rachel J Watkins; John C Watkinson; Greg D Lewy; Jim C W Fong; Sally R James; Sundaram Ramasamy; Kristien Boelaert; Jayne A Franklyn; Chris J McCabe
A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer.
Journal of cell science 2009;122(Pt 18):3393-402.
2009: Oliver J Brand; Jeffrey C Barrett; Matthew J Simmonds; Paul R Newby; Christopher J McCabe; Christopher Bruce; Boris Kysela; Jackie Carr-Smith; Thomas Brix; Penny J Hunt; Wilmar M Wiersinga; Laszlo Hegedüs; John Connell; John A H Wass; Jayne A Franklyn; Anthony P Weetman; Joanne M Heward; S C L Gough
Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease.
Human molecular genetics 2009;18(9):1704-13.
2009: S R James; Jayne A Franklyn; B J Reaves; V E Smith; S Y Chan; Timothy G Barrett; Mark D Kilby; C J McCabe
Monocarboxylate transporter 8 in neuronal cell growth.
Endocrinology 2009;150(4):1961-9.
2008: Jayne A Franklyn
Should we treat subclinical hyperthyroidism?
Nature clinical practice. Endocrinology & metabolism 2008;4(10):550-1.
2008: A A Zeitlin; Joanne M Heward; P R Newby; Jackie Carr-Smith; Jayne A Franklyn; S C L Gough; Matthew J Simmonds
Analysis of HLA class II genes in Hashimoto's thyroiditis reveals differences compared to Graves' disease.
Genes and immunity 2008;9(4):358-63.
2008: Jayne A Franklyn
Is radioiodine good for hyperthyroidism?
Nature clinical practice. Endocrinology & metabolism 2008;4(2):59.
2007: A A Syed; Matthew J Simmonds; Oliver J Brand; Jayne A Franklyn; S C L Gough; Joanne M Heward
Preliminary evidence for interaction of PTPN12 polymorphism with TSHR genotype and association with Graves' ophthalmopathy.
Clinical endocrinology 2007;67(5):663-7.
2007: Helen Pemberton; Jayne A Franklyn; Kristien Boelaert; SY Chan; Dae S Kim; C Kim; S Y Cheng; Mark D Kilby; Chris J McCabe
Separase, securin and Rad21 in neural cell growth.
Journal of cellular physiology 2007;213(1):45-53.
2007: Matthew J Simmonds; Joanna M M Howson; Joanne M Heward; Jackie Carr-Smith; Jayne A Franklyn; John A Todd; S C L Gough
A novel and major association of HLA-C in Graves' disease that eclipses the classical HLA-DRB1 effect.
Human molecular genetics 2007;16(18):2149-53.
2007: Jayne A Franklyn; Michael D Gammage
Treatment of amiodarone-associated thyrotoxicosis.
Nature clinical practice. Endocrinology & metabolism 2007;3(9):662-6.
2007: Jayne A Franklyn
Subclinical thyroid disorders--consequences and implications for treatment.
Annales d'endocrinologie 2007;68(4):229-30.
2007: P R Newby; E L Roberts-Davies; Oliver J Brand; Joanne M Heward; Jayne A Franklyn; S C L Gough; Matthew J Simmonds
Tag SNP screening of the PDCD1 gene for association with Graves' disease.
Clinical endocrinology 2007;67(1):125-8.
2007: Kristien Boelaert; V E Smith; Anna L Stratford; T Kogai; Lesley A Tannahill; John C Watkinson; Sundaram Ramasamy; Jayne A Franklyn; Chris J McCabe
PTTG and PBF repress the human sodium iodide symporter.
Oncogene 2007;26(30):4344-56.
2007: Sally R James; Jayne A Franklyn; Mark D Kilby
Placental transport of thyroid hormone.
Best practice & research. Clinical endocrinology & metabolism 2007;21(2):253-64.
2007: Michael D Gammage; James V Parle; Roger L Holder; Lesley M Roberts; F D Richard Hobbs; Sue Wilson; Michael C Sheppard; Jayne A Franklyn
Association between serum free thyroxine concentration and atrial fibrillation.
Archives of internal medicine 2007;167(9):928-34.
2007: Oliver J Brand; Christopher E Lowe; Joanne M Heward; Jayne A Franklyn; Jason D Cooper; John A Todd; S C L Gough
Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs.
Clinical endocrinology 2007;66(4):508-12.
2007: Dae S Kim; Jayne A Franklyn; V E Smith; Anna L Stratford; Helen Pemberton; Adrian Warfield; John C Watkinson; T Ishmail; Michael J O Wakelam; Chris J McCabe
Securin induces genetic instability in colorectal cancer by inhibiting double-stranded DNA repair activity.
Carcinogenesis 2007;28(3):749-59.
2007: Joanne M Heward; Oliver J Brand; Jeffrey C Barrett; Jackie Carr-Smith; Jayne A Franklyn; S C L Gough
Association of PTPN22 haplotypes with Graves' disease.
The Journal of clinical endocrinology and metabolism 2007;92(2):685-90.
2007: Faizel Osman; Jayne A Franklyn; Roger L Holder; Michael C Sheppard; Michael D Gammage
Cardiovascular manifestations of hyperthyroidism before and after antithyroid therapy: a matched case-control study.
Journal of the American College of Cardiology 2007;49(1):71-81.
2007: Allan Hackshaw; Clive Harmer; Ujjal Mallick; Masud Haq; Jayne A Franklyn
131I activity for remnant ablation in patients with differentiated thyroid cancer: A systematic review.
The Journal of clinical endocrinology and metabolism 2007;92(1):28-38.
2006: Sue Wilson; James V Parle; Lesley M Roberts; Andrea Roalfe; F D Richard Hobbs; Penny Clark; Michael C Sheppard; Michael D Gammage; Helen Pattison; Jayne A Franklyn
Prevalence of subclinical thyroid dysfunction and its relation to socioeconomic deprivation in the elderly: a community-based cross-sectional survey.
The Journal of clinical endocrinology and metabolism 2006;91(12):4809-16.
2006: N Manji; Jackie Carr-Smith; Kristien Boelaert; Amit Allahabadia; M Armitage; V K Chatterjee; J H Lazarus; Simon H S Pearce; Bijay Vaidya; S C L Gough; Jayne A Franklyn
Influences of age, gender, smoking, and family history on autoimmune thyroid disease phenotype.
The Journal of clinical endocrinology and metabolism 2006;91(12):4873-80.
2006: Dae S Kim; Jayne A Franklyn; Kristien Boelaert; Sundaram Ramasamy; John C Watkinson; Chris J McCabe
Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a vascular endothelial growth factor/kinase insert domain receptor/inhibitor of DNA binding-3 autocrine pathway.
The Journal of clinical endocrinology and metabolism 2006;91(11):4603-11.
2006: Kristien Boelaert; J Horacek; Roger L Holder; John C Watkinson; Michael C Sheppard; Jayne A Franklyn
Serum thyrotropin concentration as a novel predictor of malignancy in thyroid nodules investigated by fine-needle aspiration.
The Journal of clinical endocrinology and metabolism 2006;91(11):4295-301.
2006: Lesley M Roberts; Helen Pattison; Andrea Roalfe; Jayne A Franklyn; Sue Wilson; F D Richard Hobbs; James V Parle
Is subclinical thyroid dysfunction in the elderly associated with depression or cognitive dysfunction?
Annals of internal medicine 2006;145(8):573-81.
2006: David V Becker; Lewis E Braverman; François Delange; John T Dunn; Jayne A Franklyn; Joseph G Hollowell; Steven H Lamm; Marvin L Mitchell; Elizabeth Pearce; Jacob Robbins; Joanne Rovet
Iodine supplementation for pregnancy and lactation-United States and Canada: recommendations of the American Thyroid Association.
Thyroid : official journal of the American Thyroid Association 2006;16(10):949-51.
2006: Jayne A Franklyn
Does impaired secretion of gastric acid reduce absorption of levothyroxine?
Nature clinical practice. Endocrinology & metabolism 2006;2(10):542-3.
2006: Matthew J Simmonds; Joanne M Heward; J C Barrett; Jayne A Franklyn; S C L Gough
Association of the BTNL2 rs2076530 single nucleotide polymorphism with Graves' disease appears to be secondary to DRB1 exon 2 position beta74.
Clinical endocrinology 2006;65(4):429-32.
2006: A A Zeitlin; Joanne M Heward; Oliver J Brand; P R Newby; Jayne A Franklyn; S C L Gough; Matthew J Simmonds
Use of Tag single nucleotide polymorphisms (SNPs) to screen PTPN21: no association with Graves' disease.
Clinical endocrinology 2006;65(3):380-4.
2006: Aaron M Ranasinghe; Christopher J McCabe; David W Quinn; Sally R James; Domenico Pagano; Jayne A Franklyn; Robert S Bonser
How does glucose insulin potassium improve hemodynamic performance? Evidence for altered expression of beta-adrenoreceptor and calcium handling genes.
Circulation 2006;114(1 Suppl):I239-44.
2006: SY Chan; Jayne A Franklyn; Helen Pemberton; Judith N Bulmer; Theo J Visser; Chris J McCabe; Mark D Kilby
Monocarboxylate transporter 8 expression in the human placenta: the effects of severe intrauterine growth restriction.
The Journal of endocrinology 2006;189(3):465-71.
2006: Dae S Kim; Jayne A Franklyn; Anna L Stratford; Kristien Boelaert; John C Watkinson; Sundaram Ramasamy; Chris J McCabe
Pituitary tumor-transforming gene regulates multiple downstream angiogenic genes in thyroid cancer.
The Journal of clinical endocrinology and metabolism 2006;91(3):1119-28.
2006: Matthew J Simmonds; Joanne M Heward; Jackie Carr-Smith; Helen Foxall; Jayne A Franklyn; S C L Gough
Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease.
The Journal of clinical endocrinology and metabolism 2006;91(3):1056-61.
2006: John C Watkinson; Jayne A Franklyn; Julie F C Olliff
Detection and surgical treatment of cervical lymph nodes in differentiated thyroid cancer.
Thyroid : official journal of the American Thyroid Association 2006;16(2):187-94.
2006: N Manji; Kristien Boelaert; Michael C Sheppard; Roger L Holder; S C L Gough; Jayne A Franklyn
Lack of association between serum TSH or free T4 and body mass index in euthyroid subjects.
Clinical endocrinology 2006;64(2):125-8.
2006: J C Taylor; S C L Gough; Penny J Hunt; Thomas Brix; K Chatterjee; J M Connell; Jayne A Franklyn; L Hegedus; B G Robinson; Wilmar M Wiersinga; J A H Wass; Delilah Zabaneh; Ian Mackay; Anthony P Weetman
A genome-wide screen in 1119 relative pairs with autoimmune thyroid disease.
The Journal of clinical endocrinology and metabolism 2006;91(2):646-53.
2005: Matthew J Simmonds; Joanne M Heward; Jayne A Franklyn; S C L Gough
IL-13 and chromosome 5q31-q33: problems of identifying association within regions of linkage to Graves' disease.
Clinical endocrinology 2005;63(6):695-7.
2005: Bryan M Dechairo; Delilah Zabaneh; Joanne Collins; Oliver J Brand; Gary Dawson; Angie P Green; Ian Mackay; Jayne A Franklyn; John M Connell; J A H Wass; Wilmar M Wiersinga; Laszlo Hegedus; Thomas Brix; Bruce G Robinson; Penny J Hunt; Anthony P Weetman; Alisoun Carey; S C L Gough
Association of the TSHR gene with Graves' disease: the first disease specific locus.
European journal of human genetics : EJHG 2005;13(11):1223-30.
2005: Kristien Boelaert; Jayne A Franklyn
Thyroid hormone in health and disease.
The Journal of endocrinology 2005;187(1):1-15.
2005: Faizel Osman; Jayne A Franklyn; Michael D Gammage
Cardiovascular abnormalities in hyperthyroidism.
The American journal of medicine 2005;118(10):1175.
2005: Helen Pemberton; Jayne A Franklyn; Mark D Kilby
Thyroid hormones and fetal brain development.
Minerva ginecologica 2005;57(4):367-78.
2005: Matthew J Simmonds; Joanne M Heward; Jayne A Franklyn; S C L Gough
The CD40 Kozak SNP: a new susceptibility loci for Graves' disease?
Clinical endocrinology 2005;63(2):232-3.
2005: Shiao Y Chan; Marcus H Andrews; Rania Lingas; Chris J McCabe; Jayne A Franklyn; Mark D Kilby; Stephen G Matthews
Maternal nutrient deprivation induces sex-specific changes in thyroid hormone receptor and deiodinase expression in the fetal guinea pig brain.
The Journal of physiology 2005;566(Pt 2):467-80.
2005: Dae Kim; Helen Pemberton; Anna L Stratford; Kristien Buelaert; John C Watkinson; Victor Lopes; Jayne A Franklyn; Chris J McCabe
Pituitary tumour transforming gene (PTTG) induces genetic instability in thyroid cells.
Oncogene 2005;24(30):4861-6.
2005: Jayne A Franklyn; Michael C Sheppard; Patrick Maisonneuve
Thyroid function and mortality in patients treated for hyperthyroidism.
JAMA : the journal of the American Medical Association 2005;294(1):71-80.
2005: Anna L Stratford; Kristien Boelaert; Lesley A Tannahill; Dae S Kim; Adrian Warfield; Sundaram Ramasamy; N J L Gittoes; Lawrence S Young; Jayne A Franklyn; Chris J McCabe
Pituitary tumor transforming gene binding factor: a novel transforming gene in thyroid tumorigenesis.
The Journal of clinical endocrinology and metabolism 2005;90(7):4341-9.
2005: K J Barber; Jayne A Franklyn; Chris J McCabe; Farhat L Khanim; Judith N Bulmer; G S J Whitley; Mark D Kilby
The in vitro effects of triiodothyronine on epidermal growth factor-induced trophoblast function.
The Journal of clinical endocrinology and metabolism 2005;90(3):1655-61.
2005: Mark D Kilby; K Barber; E Hobbs; Jayne A Franklyn
Thyroid hormone action in the placenta.
Placenta 2005;26(2-3):105-13.
2005: Matthew J Simmonds; Joanna M M Howson; Joanne M Heward; Heather J Cordell; Helen Foxall; Jackie Carr-Smith; Sarah M Gibson; Neil Walker; Yaron Tomer; Jayne A Franklyn; John A Todd; S C L Gough
Regression mapping of association between the human leukocyte antigen region and Graves disease.
American journal of human genetics 2005;76(1):157-63.
2004: Kristien Boelaert; R Yu; Lesley A Tannahill; Anna L Stratford; Farhat L Khanim; Sundaram Ramasamy; J S Moore; Lawrence S Young; N J L Gittoes; Jayne A Franklyn; S Melmed; Chris J McCabe
PTTG's C-terminal PXXP motifs modulate critical cellular processes in vitro.
Journal of molecular endocrinology 2004;33(3):663-77.
2004: JE Collins; Joanne M Heward; Joanna M M Howson; Helen Foxall; Jackie Carr-Smith; Jayne A Franklyn; S C L Gough
Common allelic variants of exons 10, 12, and 33 of the thyroglobulin gene are not associated with autoimmune thyroid disease in the United Kingdom.
The Journal of clinical endocrinology and metabolism 2004;89(12):6336-9.
2004: Deborah Smyth; Jason D Cooper; Joanne E Collins; Joanne M Heward; Jayne A Franklyn; Joanna M M Howson; Adrian Vella; Sarah Nutland; Helen E Rance; Lisa Maier; Bryan J Barratt; Cristian Guja; Constantin Ionescu-Tîrgoviste; David A Savage; David D Dunger; Barry Widmer; David P Strachan; Susan M Ring; Neil Walker; David G Clayton; Rebecca C J Twells; S C L Gough; John A Todd
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.
Diabetes 2004;53(11):3020-3.
2004: Shiao Chan; P G Murray; Jayne A Franklyn; Chris J McCabe; Mark D Kilby
The use of laser capture microdissection (LCM) and quantitative polymerase chain reaction to define thyroid hormone receptor expression in human 'term' placenta.
Placenta 2004;25(8-9):758-62.
2004: Faizel Osman; Jayne A Franklyn; Jacqueline Daykin; Saqib Chowdhary; Roger L Holder; Michael C Sheppard; Michael D Gammage
Heart rate variability and turbulence in hyperthyroidism before, during, and after treatment.
The American journal of cardiology 2004;94(4):465-9.
2004: Joanne M Heward; Matthew J Simmonds; Jackie Carr-Smith; Helen Foxall; Jayne A Franklyn; S C L Gough
A single nucleotide polymorphism in the CD40 gene on chromosome 20q (GD-2) provides no evidence for susceptibility to Graves' disease in UK Caucasians.
Clinical endocrinology 2004;61(2):269-72.
2004: Lorraine Harper; L Chin; Jacqueline Daykin; Amit Allahabadia; Joanne M Heward; S C L Gough; Caroline O S Savage; Jayne A Franklyn
Propylthiouracil and carbimazole associated-antineutrophil cytoplasmic antibodies (ANCA) in patients with Graves' disease.
Clinical endocrinology 2004;60(6):671-5.
2004: Matthew J Simmonds; Joanne M Heward; Joanna M M Howson; Helen Foxall; Ratnasingam Nithiyananthan; Jayne A Franklyn; S C L Gough
A systematic approach to the assessment of known TNF-alpha polymorphisms in Graves' disease.
Genes and immunity 2004;5(4):267-73.
2004: Karen F Tait; Ratnasingam Nithiyananthan; Joanne M Heward; Anthony H Barnett; Jayne A Franklyn; S C L Gough
Polymorphisms of interleukin 4 receptor gene and interleukin 10 gene are not associated with Graves' disease in the UK.
Autoimmunity 2004;37(3):189-94.
2004: JE Collins; Joanne M Heward; Ratnasingam Nithiyananthan; S Nejentsev; John A Todd; Jayne A Franklyn; S C L Gough
Lack of association of the vitamin D receptor gene with Graves' disease in UK Caucasians.
Clinical endocrinology 2004;60(5):618-24.
2004: Karen F Tait; JE Collins; Joanne M Heward; Iain A Eaves; Hywel Snook; Jayne A Franklyn; Anthony H Barnett; John A Todd; Mel Maranian; Alastair Compston; Stephen Sawcer; S C L Gough
Evidence for a Type 1 diabetes-specific mechanism for the insulin gene-associated IDDM2 locus rather than a general influence on autoimmunity.
Diabetic medicine : a journal of the British Diabetic Association 2004;21(3):267-70.
2004: Martin I Surks; EDUARDO ORTIZ; Gilbert H Daniels; Clark T Sawin; Nananda F Col; Rhoda H Cobin; Jayne A Franklyn; Jerome M Hershman; Kenneth D Burman; Margo A Denke; Colum Gorman; Richard S Cooper; Neil J Weissman
Subclinical thyroid disease: scientific review and guidelines for diagnosis and management.
JAMA : the journal of the American Medical Association 2004;291(2):228-38.
2003: Jiri Horacek; Jayne A Franklyn
Radioiodine treatment of Graves' hyperthyroidism.
The Journal of clinical endocrinology and metabolism 2003;88(12):6113.
2003: JE Collins; Joanne M Heward; Jackie Carr-Smith; Jacqueline Daykin; Jayne A Franklyn; S C L Gough
Association of a rare thyroglobulin gene microsatellite variant with autoimmune thyroid disease.
The Journal of clinical endocrinology and metabolism 2003;88(10):5039-42.
2003: Shiao Chan; Stivelia Kachilele; E Hobbs; Judith N Bulmer; Kristien Boelaert; Chris J McCabe; PM Driver; Arthur R Bradwell; M Kester; Theo J Visser; Jayne A Franklyn; Mark D Kilby
Placental iodothyronine deiodinase expression in normal and growth-restricted human pregnancies.
The Journal of clinical endocrinology and metabolism 2003;88(9):4488-95.
2003: Emma L Davies; James D Ramsden; Helen C Cocks; Peter F Searle; John C Watkinson; Hikaru Ueno; Ann Logan; Jayne A Franklyn; Vivien Mautner; Sundaram Ramasamy
Adenovirus-mediated expression of dominant negative fibroblast growth factor (FGF) receptor 1 in thyroid cells blocks FGF effects and reduces goitrogenesis in mice.
The Journal of clinical endocrinology and metabolism 2003;88(9):4472-80.
2003: Kristien Boelaert; Lesley A Tannahill; Judith N Bulmer; Stivelia Kachilele; SY Chan; D Kim; N J L Gittoes; Jayne A Franklyn; Mark D Kilby; Chris J McCabe
A potential role for PTTG/securin in the developing human fetal brain.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1631-9.
2003: Helen C Cocks; Stuart Thompson; Frances E Turner; Ann Logan; Jayne A Franklyn; John C Watkinson; Sundaram Ramasamy
Role and regulation of the fibroblast growth factor axis in human thyroid follicular cells.
American journal of physiology. Endocrinology and metabolism 2003;285(3):E460-9.
2003: Shiao Chan; Chris J McCabe; Theo J Visser; Jayne A Franklyn; Mark D Kilby
Thyroid hormone responsiveness in N-Tera-2 cells.
The Journal of endocrinology 2003;178(1):159-67.
2003: Jayne A Franklyn
Hashimoto's enchephalopathy.
Lancet 2003;361(9372):1912; author reply 1912-3.
2003: Mark Vanderpump; Jayne A Franklyn
Thyroid function tests and hypothyroidism. Restoring serum TSH to reference range should be goal of replacement.
BMJ (Clinical research ed.) 2003;326(7398):1086-7; author reply 1087.
2003: Kristien Boelaert; Chris J McCabe; Lesley A Tannahill; N J L Gittoes; Roger L Holder; John C Watkinson; Arthur R Bradwell; Michael C Sheppard; Jayne A Franklyn
Pituitary tumor transforming gene and fibroblast growth factor-2 expression: potential prognostic indicators in differentiated thyroid cancer.
The Journal of clinical endocrinology and metabolism 2003;88(5):2341-7.
2003: Kristien Boelaert; Jayne A Franklyn
Sodium iodide symporter: a novel strategy to target breast, prostate, and other cancers?
Lancet 2003;361(9360):796-7.
2003: Chris J McCabe; J S Khaira; Kristien Boelaert; Anthony P Heaney; Lesley A Tannahill; S Hussain; R Mitchell; J Olliff; Michael C Sheppard; Jayne A Franklyn; N J L Gittoes
Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour.
Clinical endocrinology 2003;58(2):141-50.
2003: Jayne A Franklyn
Thyrotoxicosis.
Clinical medicine (London, England) 2003;3(1):11-5.
2002: Xian Zhang; Roger J A Grand; Chris J McCabe; Jayne A Franklyn; Phillip H Gallimore; Andrew S Turnell
Transcriptional regulation of the human glycoprotein hormone common alpha subunit gene by cAMP-response-element-binding protein (CREB)-binding protein (CBP)/p300 and p53.
The Biochemical journal 2002;368(Pt 1):191-201.
2002: Matthew J Simmonds; Joanne M Heward; M Ann Kelly; Amit Allahabadia; Helen Foxall; Caroline Gordon; Jayne A Franklyn; S C L Gough
A nonsense mutation in exon 2 of the DNase I gene is not present in UK subjects with systemic lupus erythematosus and Graves' disease: Comment on the article by Rood et al.
Arthritis and rheumatism 2002;46(11):3109-10.
2002: Shiao Chan; Stivelia Kachilele; Chris J McCabe; Lesley A Tannahill; Kristien Boelaert; N J L Gittoes; Theo J Visser; Jayne A Franklyn; Mark D Kilby
Early expression of thyroid hormone deiodinases and receptors in human fetal cerebral cortex.
Brain research. Developmental brain research 2002;138(2):109-16.
2002: Chris J McCabe; Kristien Boelaert; Lesley A Tannahill; Anthony P Heaney; Anna L Stratford; J S Khaira; S Hussain; Michael C Sheppard; Jayne A Franklyn; N J L Gittoes
Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors.
The Journal of clinical endocrinology and metabolism 2002;87(9):4238-44.
2002: Faizel Osman; Michael D Gammage; Jayne A Franklyn
Hyperthyroidism and cardiovascular morbidity and mortality.
Thyroid : official journal of the American Thyroid Association 2002;12(6):483-7.
2002: Lesley A Tannahill; Theo J Visser; Chris J McCabe; Stivelia Kachilele; Kristien Boelaert; Michael C Sheppard; Jayne A Franklyn; N J L Gittoes
Dysregulation of iodothyronine deiodinase enzyme expression and function in human pituitary tumours.
Clinical endocrinology 2002;56(6):735-43.
2002: Faizel Osman; Jayne A Franklyn; Michael C Sheppard; Michael D Gammage
Successful treatment of amiodarone-induced thyrotoxicosis.
Circulation 2002;105(11):1275-7.
2002: Faizel Osman; Michael D Gammage; Michael C Sheppard; Jayne A Franklyn
Clinical review 142: cardiac dysrhythmias and thyroid dysfunction: the hidden menace?
The Journal of clinical endocrinology and metabolism 2002;87(3):963-7.
2002: Michael C Sheppard; Roger L Holder; Jayne A Franklyn
Levothyroxine treatment and occurrence of fracture of the hip.
Archives of internal medicine 2002;162(3):338-43.
2002: Ingrid Dahlman; Iain A Eaves; Roman Kosoy; V Anne Morrison; Joanne M Heward; S C L Gough; Amit Allahabadia; Jayne A Franklyn; Jaakko Tuomilehto; Eva Tuomilehto-Wolf; Francesco Cucca; Cristian Guja; Constantin Ionescu-Tirgoviste; Helen Stevens; Philippa Carr; Sarah Nutland; Patricia McKinney; Julian P H Shield; William Wang; Heather J Cordell; Neil Walker; John A Todd; Patrick Concannon
Parameters for reliable results in genetic association studies in common disease.
Nature genetics 2002;30(2):149-50.
2002: Ratnasingam Nithiyananthan; Joanne M Heward; Amit Allahabadia; Jayne A Franklyn; S C L Gough
Polymorphism of the CTLA-4 gene is associated with autoimmune hypothyroidism in the United Kingdom.
Thyroid : official journal of the American Thyroid Association 2002;12(1):3-6.
2001: Faizel Osman; Michael D Gammage; Jayne A Franklyn
Thyroid disease and its treatment: short-term and long-term cardiovascular consequences.
Current opinion in pharmacology 2001;1(6):626-31.
2001: Amit Allahabadia; Joanne M Heward; Ratnasingam Nithiyananthan; S M Gibson; T T Reuser; PM Dodson; Jayne A Franklyn; S C L Gough
MHC class II region, CTLA4 gene, and ophthalmopathy in patients with Graves' disease.
Lancet 2001;358(9286):984-5.
2001: James V Parle; P Maisonneuve; Michael C Sheppard; P Boyle; Jayne A Franklyn
Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study.
Lancet 2001;358(9285):861-5.
2001: J Dale; Jacqueline Daykin; Roger L Holder; Michael C Sheppard; Jayne A Franklyn
Weight gain following treatment of hyperthyroidism.
Clinical endocrinology 2001;55(2):233-9.
2001: Joanne M Heward; Ratnasingam Nithiyananthan; Amit Allahabadia; S Gibson; Jayne A Franklyn; S C L Gough
No association of an interleukin 4 gene promoter polymorphism with Graves' disease in the United Kingdom.
The Journal of clinical endocrinology and metabolism 2001;86(8):3861-3.
2001: Amit Allahabadia; Jacqueline Daykin; Michael C Sheppard; S C L Gough; Jayne A Franklyn
Radioiodine treatment of hyperthyroidism-prognostic factors for outcome.
The Journal of clinical endocrinology and metabolism 2001;86(8):3611-7.
2001: Faizel Osman; John Ayuk; J Dale; Jayne A Franklyn; Michael D Gammage
Thyrotoxicosis with heart block.
Journal of the Royal Society of Medicine 2001;94(7):346-8.
2001: H Kumar; Jacqueline Daykin; Roger L Holder; John C Watkinson; Michael C Sheppard; Jayne A Franklyn
An audit of management of differentiated thyroid cancer in specialist and non-specialist clinic settings.
Clinical endocrinology 2001;54(6):719-23.
2000: Mark D Kilby; N J L Gittoes; C McCabe; Julie Verhaeg; Jayne A Franklyn
Expression of thyroid receptor isoforms in the human fetal central nervous system and the effects of intrauterine growth restriction.
Clinical endocrinology 2000;53(4):469-77.
2000: Jayne A Franklyn
Lack of consensus in Europe in the management of nontoxic multinodular goitre.
Clinical endocrinology 2000;53(1):3-4.
2000: Charles M Bishop; Chris J McCabe; N J L Gittoes; Patrick J Butler; Jayne A Franklyn
Tissue-specific regulation of thyroid hormone receptor mRNA isoforms and target gene proteins in domestic ducks.
The Journal of endocrinology 2000;165(3):607-15.
2000: Ratnasingam Nithiyananthan; Joanne M Heward; Amit Allahabadia; Anthony H Barnett; Jayne A Franklyn; S C L Gough
A heterozygous deletion of the autoimmune regulator (AIRE1) gene, autoimmune thyroid disease, and type 1 diabetes: no evidence for association.
The Journal of clinical endocrinology and metabolism 2000;85(3):1320-2.
2000: Amit Allahabadia; Jacqueline Daykin; Roger L Holder; Michael C Sheppard; S C L Gough; Jayne A Franklyn
Age and gender predict the outcome of treatment for Graves' hyperthyroidism.
The Journal of clinical endocrinology and metabolism 2000;85(3):1038-42.
1999: Jayne A Franklyn
Thyroid disease and its treatment: short- and long-term consequences.
Journal of the Royal College of Physicians of London 1999;33(6):564-7.
1999: H Kumar; Jacqueline Daykin; Roger L Holder; John C Watkinson; Michael C Sheppard; Jayne A Franklyn
Gender, clinical findings, and serum thyrotropin measurements in the prediction of thyroid neoplasia in 1005 patients presenting with thyroid enlargement and investigated by fine-needle aspiration cytology.
Thyroid : official journal of the American Thyroid Association 1999;9(11):1105-9.
1999: Joanne M Heward; Amit Allahabadia; Michael C Sheppard; Anthony H Barnett; Jayne A Franklyn; S C L Gough
Association of the large multifunctional proteasome (LMP2) gene with Graves' disease is a result of linkage disequilibrium with the HLA haplotype DRB1*0304-DQB1*02-DQA1*0501.
Clinical endocrinology 1999;51(1):115-8.
1999: Joanne M Heward; Amit Allahabadia; M Armitage; Andrew T Hattersley; PM Dodson; K Macleod; Jackie Carr-Smith; Jacqueline Daykin; A Daly; Michael C Sheppard; Roger L Holder; Anthony H Barnett; Jayne A Franklyn; S C L Gough
The development of Graves' disease and the CTLA-4 gene on chromosome 2q33.
The Journal of clinical endocrinology and metabolism 1999;84(7):2398-401.
1999: Jayne A Franklyn; Patrick Maisonneuve; M Sheppard; J Betteridge; P Boyle
Cancer incidence and mortality after radioiodine treatment for hyperthyroidism: a population-based cohort study.
Lancet 1999;353(9170):2111-5.
1999: Chris J McCabe; N J L Gittoes; Michael C Sheppard; Jayne A Franklyn
Increased MEN1 mRNA expression in sporadic pituitary tumours.
Clinical endocrinology 1999;50(6):727-33.
1999: Joanne M Heward; Amit Allahabadia; C Gordon; Michael C Sheppard; Anthony H Barnett; Jayne A Franklyn; S C L Gough
The interleukin-1 receptor antagonist gene shows no allelic association with three autoimmune diseases.
Thyroid : official journal of the American Thyroid Association 1999;9(6):627-8.
1999: H Kumar; Jacqueline Daykin; J Betteridge; Roger L Holder; Michael C Sheppard; Jayne A Franklyn
Prevalence and clinical usefulness of thyroid antibodies in different disease states of the thyroid.
Clinical endocrinology 1999;50(5):679-80.
1999: J S Khaira; Jayne A Franklyn
Thyroid conditions in older patients.
The Practitioner 1999;243(1596):214-8, 221.
1999: Joanne M Heward; Caroline Gordon; Amit Allahabadia; Anthony H Barnett; Jayne A Franklyn; S C L Gough
The A-G polymorphism in exon 1 of the CTLA-4 gene is not associated with systemic lupus erythematosus.
Annals of the rheumatic diseases 1999;58(3):193-5.
1999: Amit Allahabadia; Joanne M Heward; Jackie Carr-Smith; Jacqueline Daykin; Anthony H Barnett; Michael C Sheppard; Jayne A Franklyn; S C L Gough
Sharing of susceptibility loci between autoimmune diseases: lack of association of the insulin gene region with Graves' disease.
Thyroid : official journal of the American Thyroid Association 1999;9(3):317-8.
1999: Chris J McCabe; N J L Gittoes; Michael C Sheppard; Jayne A Franklyn
Thyroid receptor alpha1 and alpha2 mutations in nonfunctioning pituitary tumors.
The Journal of clinical endocrinology and metabolism 1999;84(2):649-53.
1998: A K Lim; Jacqueline Daykin; Roger L Holder; Michael C Sheppard; Jayne A Franklyn
Measurement of serum TSH in the investigation of patients presenting with thyroid enlargement.
QJM : monthly journal of the Association of Physicians 1998;91(10):687-9.
1998: Joanne M Heward; Amit Allahabadia; Jacqueline Daykin; Jackie Carr-Smith; A Daly; M Armitage; PM Dodson; Michael C Sheppard; Anthony H Barnett; Jayne A Franklyn; S C L Gough
Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves' disease: replication using a population case control and family-based study.
The Journal of clinical endocrinology and metabolism 1998;83(10):3394-7.
1998: Joanne M Heward; Amit Allahabadia; Jackie Carr-Smith; Jacqueline Daykin; Clive S Cockram; Caroline Gordon; Anthony H Barnett; Jayne A Franklyn; S C L Gough
No evidence for allelic association of a human CTLA-4 promoter polymorphism with autoimmune thyroid disease in either population-based case-control or family-based studies.
Clinical endocrinology 1998;49(3):331-4.
1998: Amit Allahabadia; Joanne M Heward; Catherine H Mijovic; Jackie Carr-Smith; Jacqueline Daykin; Clive S Cockram; Anthony H Barnett; Michael C Sheppard; Jayne A Franklyn; S C L Gough
Lack of association between polymorphism of the thyrotropin receptor gene and Graves' disease in United Kingdom and Hong Kong Chinese patients: case control and family-based studies.
Thyroid : official journal of the American Thyroid Association 1998;8(9):777-80.
1998: Mark D Kilby; Julie Verhaeg; N J L Gittoes; David A Somerset; Penny M S Clark; Jayne A Franklyn
Circulating thyroid hormone concentrations and placental thyroid hormone receptor expression in normal human pregnancy and pregnancy complicated by intrauterine growth restriction (IUGR).
The Journal of clinical endocrinology and metabolism 1998;83(8):2964-71.
1998: Chris J McCabe; NJ Yarwood; J A Gurr; N J L Gittoes; Michael C Sheppard; Jayne A Franklyn
Differential regulation of the human thyrotropin alpha-subunit promoter by thyroid hormone receptors alpha1 and beta1.
Thyroid : official journal of the American Thyroid Association 1998;8(7):601-8.
1998: N J L Gittoes; Chris J McCabe; Julie Verhaeg; Michael C Sheppard; Jayne A Franklyn
Retinoid X receptor expression in the normal pituitary and clinically 'non-functioning' pituitary tumours.
Clinical endocrinology 1998;48(4):425-33.
1998: N J L Gittoes; Jayne A Franklyn
Hyperthyroidism. Current treatment guidelines.
Drugs 1998;55(4):543-53.
1998: S D Thompson; Jayne A Franklyn; John C Watkinson; Julie Verhaeg; Michael C Sheppard; Sundaram Ramasamy
Fibroblast growth factors 1 and 2 and fibroblast growth factor receptor 1 are elevated in thyroid hyperplasia.
The Journal of clinical endocrinology and metabolism 1998;83(4):1336-41.
1998: Jayne A Franklyn; Patrick Maisonneuve; Michael C Sheppard; J Betteridge; P Boyle
Mortality after the treatment of hyperthyroidism with radioactive iodine.
The New England journal of medicine 1998;338(11):712-8.
1998: N J L Gittoes; Chris J McCabe; Julie Verhaeg; Michael C Sheppard; Jayne A Franklyn
An abnormality of thyroid hormone receptor expression may explain abnormal thyrotropin production in thyrotropin-secreting pituitary tumors.
Thyroid : official journal of the American Thyroid Association 1998;8(1):9-14.
1997: Jayne A Franklyn
Management guidelines for hyperthyroidism.
Baillière's clinical endocrinology and metabolism 1997;11(3):561-71.
1997: N J L Gittoes; Chris J McCabe; Julie Verhaeg; Michael C Sheppard; Jayne A Franklyn
Thyroid hormone and estrogen receptor expression in normal pituitary and nonfunctioning tumors of the anterior pituitary.
The Journal of clinical endocrinology and metabolism 1997;82(6):1960-7.
1997: PH Davies; Michael C Sheppard; Jayne A Franklyn
Inflammatory cytokines and type I 5'-deiodinase expression in phi1 rat liver cells.
Molecular and cellular endocrinology 1997;129(2):191-8.
1996: P H Davies; Michael C Sheppard; Jayne A Franklyn
Regulation of type I 5'-deiodinase by thyroid hormone and dexamethasone in rat liver and kidney cells.
Thyroid : official journal of the American Thyroid Association 1996;6(3):221-8.
1996: G W Ching; Jayne A Franklyn; T J Stallard; J Daykin; Michael C Sheppard; Michael D Gammage
Cardiac hypertrophy as a result of long-term thyroxine therapy and thyrotoxicosis.
Heart (British Cardiac Society) 1996;75(4):363-8.
1996: Jayne A Franklyn; M D Gammage
Thyroid disease: effects on cardiovascular function.
Trends in endocrinology and metabolism: TEM 1996;7(2):50-4.
1996: N J L Gittoes; Martin R Miller; Jacqueline Daykin; Michael C Sheppard; Jayne A Franklyn
Upper airways obstruction in 153 consecutive patients presenting with thyroid enlargement.
BMJ (Clinical research ed.) 1996;312(7029):484.
1996: P H Davies; E G Black; Michael C Sheppard; Jayne A Franklyn
Relation between serum interleukin-6 and thyroid hormone concentrations in 270 hospital in-patients with non-thyroidal illness.
Clinical endocrinology 1996;44(2):199-205.
1996: A Chamba; J Neuberger; Alastair J Strain; J Hopkins; Michael C Sheppard; Jayne A Franklyn
Expression and function of thyroid hormone receptor variants in normal and chronically diseased human liver.
The Journal of clinical endocrinology and metabolism 1996;81(1):360-7.
1995: Jayne A Franklyn; J Betteridge; Roger L Holder; Michael C Sheppard
Effect of estrogen replacement therapy upon bone mineral density in thyroxine-treated postmenopausal women with a past history of thyrotoxicosis.
Thyroid : official journal of the American Thyroid Association 1995;5(5):359-63.
1995: Jayne A Franklyn
'Subclinical hypothyroidism': to treat or not to treat, that is the question.
Clinical endocrinology 1995;43(4):443-4.
1995: N J L Gittoes; Jayne A Franklyn
Drug-induced thyroid disorders.
Drug safety : an international journal of medical toxicology and drug experience 1995;13(1):46-55.
1995: Jayne A Franklyn
Hypothyroidism: lab results or clinical judgement?
The Practitioner 1995;239(1550):330-3.
1995: Jayne A Franklyn; Jacqueline Daykin; Roger L Holder; Michael C Sheppard
Radioiodine therapy compared in patients with toxic nodular or Graves' hyperthyroidism.
QJM : monthly journal of the Association of Physicians 1995;88(3):175-80.
1995: P Burra; N J Fitch; A Kapadi; Jayne A Franklyn; Michael C Sheppard; David B Ramsden; E Elias
The effects of ethanol, 3,5,3'-triiodothyronine (T3) and oestradiol (E2) on thyroid hormone nuclear receptor expression in human hepatocyte primary cultures.
Alcohol and alcoholism (Oxford, Oxfordshire) 1995;30(2):219-21.
1995: Sundaram Ramasamy; J M Hopkins; Jayne A Franklyn; G D Johnson; D S Sanders; Michael C Sheppard
Expression of fibroblast growth factors in thyroid cancer.
The Journal of clinical endocrinology and metabolism 1995;80(3):1006-11.
1994: Jayne A Franklyn; J Betteridge; Roger L Holder; Jacqueline Daykin; J Lilley; M Sheppard
Bone mineral density in thyroxine treated females with or without a previous history of thyrotoxicosis.
Clinical endocrinology 1994;41(4):425-32.
1994: Jayne A Franklyn
The management of hyperthyroidism.
The New England journal of medicine 1994;330(24):1731-8.
1994: Jayne A Franklyn; E G Black; J Betteridge; Michael C Sheppard
Comparison of second and third generation methods for measurement of serum thyrotropin in patients with overt hyperthyroidism, patients receiving thyroxine therapy, and those with nonthyroidal illness.
The Journal of clinical endocrinology and metabolism 1994;78(6):1368-71.
1994: G R Williams; Jayne A Franklyn
Physiology of the steroid-thyroid hormone nuclear receptor superfamily.
Baillière's clinical endocrinology and metabolism 1994;8(2):241-66.
1993: NJ Yarwood; J A Gurr; Michael C Sheppard; Jayne A Franklyn
Estradiol modulates thyroid hormone regulation of the human glycoprotein hormone alpha subunit gene.
The Journal of biological chemistry 1993;268(29):21984-9.
1993: Jayne A Franklyn
Graves' ophthalmopathy and the TSH receptor.
Lancet 1993;342(8867):318-9.
1993: M A Baxter; P M Stewart; Jacqueline Daykin; Michael C Sheppard; Jayne A Franklyn
Radioiodine therapy for hyperthyroidism in young patients--perception of risk and use.
The Quarterly journal of medicine 1993;86(8):495-9.
1993: Jayne A Franklyn; Jacqueline Daykin; J Young; G D Oates; Michael C Sheppard
Fine needle aspiration cytology in diffuse or multinodular goitre compared with solitary thyroid nodules.
BMJ (Clinical research ed.) 1993;307(6898):240.
1993: Jayne A Franklyn; Jacqueline Daykin; J Betteridge; E A Hughes; Roger L Holder; S R Jones; Michael C Sheppard
Thyroxine replacement therapy and circulating lipid concentrations.
Clinical endocrinology 1993;38(5):453-9.
1993: Jayne A Franklyn
Thyroid hormone resistance syndromes--are generalized and selective pituitary resistance part of the same disorder?
Clinical endocrinology 1993;38(3):235-6.
1993: James V Parle; Jayne A Franklyn; K W Cross; S R Jones; Michael C Sheppard
Thyroxine prescription in the community: serum thyroid stimulating hormone level assays as an indicator of undertreatment or overtreatment.
The British journal of general practice : the journal of the Royal College of General Practitioners 1993;43(368):107-9.
1993: D H MacIver; Nicola K Green; M D Gammage; H Durkin; Ashley S Izzard; Jayne A Franklyn; Anthony M Heagerty
Effect of experimental hypertension on phosphoinositide hydrolysis and proto-oncogene expression in cardiovascular tissues.
Journal of vascular research 1993;30(1):13-22.
1993: Nicola K Green; M D Gammage; Jayne A Franklyn; Anthony M Heagerty; Michael C Sheppard
Regulation of beta myosin heavy chain, c-myc and c-fos proto-oncogenes in thyroid hormone-induced hypertrophy of the rat myocardium.
Clinical science (London, England : 1979) 1993;84(1):61-7.
1992: James V Parle; Jayne A Franklyn; K W Cross; S R Jones; Michael C Sheppard
Circulating lipids and minor abnormalities of thyroid function.
Clinical endocrinology 1992;37(5):411-4.
1992: Michael C Sheppard; Jayne A Franklyn
Management of the single thyroid nodule.
Clinical endocrinology 1992;37(5):398-401.
1992: D Jenkins; M A Penny; J A Fletcher; K H Jacobs; Catherine H Mijovic; Jayne A Franklyn; Michael C Sheppard
HLA class II gene polymorphism contributes little to Hashimoto's thyroiditis.
Clinical endocrinology 1992;37(2):141-5.
1992: P H Davies; Jayne A Franklyn; Michael C Sheppard
Treatment of amiodarone induced thyrotoxicosis with carbimazole alone and continuation of amiodarone.
BMJ (Clinical research ed.) 1992;305(6847):224-5.
1992: Jayne A Franklyn; J Betteridge; Jacqueline Daykin; Roger L Holder; G D Oates; James V Parle; J Lilley; D A Heath; Michael C Sheppard
Long-term thyroxine treatment and bone mineral density.
Lancet 1992;340(8810):9-13.
1992: P H Davies; Jayne A Franklyn; Jacqueline Daykin; Michael C Sheppard
The significance of TSH values measured in a sensitive assay in the follow-up of hyperthyroid patients treated with radioiodine.
The Journal of clinical endocrinology and metabolism 1992;74(5):1189-94.
1992: C B Whorwood; Jayne A Franklyn; Michael C Sheppard; Paul M Stewart
Tissue localization of 11 beta-hydroxysteroid dehydrogenase and its relationship to the glucocorticoid receptor.
The Journal of steroid biochemistry and molecular biology 1992;41(1):21-8.
1992: Michael C Sheppard; Jayne A Franklyn; NJ Yarwood; J A Gurr
Thyroid hormone regulation of human pituitary alpha subunit gene expression.
Acta medica Austriaca 1992;19 Suppl 1():66-8.
1991: James V Parle; Jayne A Franklyn; K W Cross; S R Jones; Michael C Sheppard
Assessment of a screening process to detect patients aged 60 years and over at high risk of hypothyroidism.
The British journal of general practice : the journal of the Royal College of General Practitioners 1991;41(351):414-6.
1991: G R Williams; Jayne A Franklyn; Michael C Sheppard
Thyroid hormone and glucocorticoid regulation of receptor and target gene mRNAs in pituitary GH3 cells.
Molecular and cellular endocrinology 1991;80(1-3):127-38.
1991: Nicola K Green; M D Gammage; Jayne A Franklyn; Michael C Sheppard
Regulation by thyroid status of c-myc, c-fos and H-ras mRNAs in the rat myocardium.
The Journal of endocrinology 1991;130(2):239-44.
1991: Paul M Stewart; C B Whorwood; P Barber; J Gregory; C Monder; Jayne A Franklyn; Michael C Sheppard
Localization of renal 11 beta-dehydrogenase by in situ hybridization: autocrine not paracrine protector of the mineralocorticoid receptor.
Endocrinology 1991;128(4):2129-35.
1991: Jayne A Franklyn
Syndromes of thyroid hormone resistance.
Clinical endocrinology 1991;34(3):237-45.
1991: James V Parle; Jayne A Franklyn; K W Cross; S C Jones; Michael C Sheppard
Prevalence and follow-up of abnormal thyrotrophin (TSH) concentrations in the elderly in the United Kingdom.
Clinical endocrinology 1991;34(1):77-83.
1991: Jayne A Franklyn; Jacqueline Daykin; Z Drolc; M Farmer; Michael C Sheppard
Long-term follow-up of treatment of thyrotoxicosis by three different methods.
Clinical endocrinology 1991;34(1):71-6.
1991: P H Davies; Jayne A Franklyn
The effects of drugs on tests of thyroid function.
European journal of clinical pharmacology 1991;40(5):439-51.
1990: J A Ahlquist; Jayne A Franklyn; David B Ramsden; Michael C Sheppard
Regulation of alpha and thyrotrophin-beta subunit mRNA levels by androgens in the female rat.
Journal of molecular endocrinology 1990;5(1):1-6.
1990: N J Balfour; Jayne A Franklyn; J A Gurr; Michael C Sheppard
Multiple DNA elements determine basal and thyroid hormone regulated expression of the human glycoprotein alpha subunit gene in pituitary cells.
Journal of molecular endocrinology 1990;4(2):187-90.
1990: Jayne A Franklyn; Michael C Sheppard
Thyroxine replacement treatment and osteoporosis.
BMJ (Clinical research ed.) 1990;300(6726):693-4.
1989: Jayne A Franklyn; S King; J A Ahlquist; Michael C Sheppard
Effect of hypothyroidism and thyroid hormone treatment of the rat on hepatic Spot 14 and thyroxine binding prealbumin mRNAs.
Acta endocrinologica 1989;121(3):383-8.
1989: J A Ahlquist; Jayne A Franklyn; Michael C Sheppard; David B Ramsden
Thyroid hormone response elements in pituitary genes.
Biochimica et biophysica acta 1989;1008(2):251-4.
1989: Nicola K Green; Jayne A Franklyn; J A Ahlquist; M D Gammage; Michael C Sheppard
Differential regulation by thyroid hormones of myosin heavy chain alpha and beta mRNAs in the rat ventricular myocardium.
The Journal of endocrinology 1989;122(1):193-200.
1989: J A Ahlquist; Jayne A Franklyn; David B Ramsden; Michael C Sheppard
The influence of dexamethasone on serum thyrotrophin and thyrotrophin synthesis in the rat.
Molecular and cellular endocrinology 1989;64(1):55-61.
1989: Jayne A Franklyn; Nicola K Green; M D Gammage; J A Alhquist; Michael C Sheppard
Regulation of alpha- and beta-myosin heavy chain messenger RNAs in the rat myocardium by amiodarone and by thyroid status.
Clinical science (London, England : 1979) 1989;76(5):463-7.
1989: J A Ahlquist; Jayne A Franklyn; David B Ramsden; Michael C Sheppard
Nuclear proteins from the rat pituitary gland bind to regulatory sequences of the thyrotrophin-beta gene.
Journal of molecular endocrinology 1989;2(2):85-91.
1988: Jayne A Franklyn; D F Wood; N J Balfour; Michael C Sheppard
Effect of triiodothyronine treatment on thyrotrophin beta- and alpha-messenger RNAs in the pituitary of the euthyroid rat.
Molecular and cellular endocrinology 1988;60(1):1-5.
1988: Jayne A Franklyn; Michael C Sheppard
Hormonal control of gene expression.
Clinical endocrinology 1988;29(3):337-48.
1988: Jayne A Franklyn; Michael C Sheppard
Thyrotrophin gene regulation.
The Journal of endocrinology 1988;117(2):161-5.
1987: M D Gammage; Jayne A Franklyn; SD Logan
Effects of amiodarone and thyroid dysfunction on myocardial calcium, serum calcium and thyroid hormones in the rat.
British journal of pharmacology 1987;92(2):363-70.
1987: Jayne A Franklyn; D F Wood; N J Balfour; David B Ramsden; Kevin Docherty; Michael C Sheppard
Modulation by oestrogen of thyroid hormone effects on thyrotrophin gene expression.
The Journal of endocrinology 1987;115(1):53-9.
1987: Jayne A Franklyn; M D Gammage; Michael C Sheppard
Amiodarone and thyroid hormone effects on anterior pituitary hormone gene expression.
Clinical endocrinology 1987;27(3):373-82.
1987: Jayne A Franklyn; D F Wood; N J Balfour; David B Ramsden; Kevin Docherty; W W Chin; Michael C Sheppard
Effect of hypothyroidism and thyroid hormone replacement in vivo on pituitary cytoplasmic concentrations of thyrotropin-beta and alpha-subunit messenger ribonucleic acids.
Endocrinology 1987;120(6):2279-88.
1987: D F Wood; Jayne A Franklyn; Kevin Docherty; David B Ramsden; Michael C Sheppard
The effect of thyroid hormones on growth hormone gene expression in vivo in rats.
The Journal of endocrinology 1987;112(3):459-63.
1987: M D Gammage; Jayne A Franklyn
Amiodarone and the thyroid.
The Quarterly journal of medicine 1987;62(238):83-6.
1987: J A Ahlquist; Jayne A Franklyn; D F Wood; N J Balfour; Kevin Docherty; Michael C Sheppard; David B Ramsden
Hormonal regulation of thyrotrophin synthesis and secretion.
Hormone and metabolic research. Supplement series 1987;17():86-9.