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Alberto Frasch

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M Eugenia Giorgi; Laura Ratier; Rosalía Agusti; Alberto C C Frasch; Rosa M de Lederkremer
Improved bioavailability of inhibitors of Trypanosoma cruzi trans-sialidase: PEGylation of lactose analogs with multiarm polyethyleneglycol.
Claudia R De Marchi; Javier M Di Noia; Alberto C C Frasch; Igor Almeida; Vicente Amato Neto; Carlos A Buscaglia
Evaluation of a recombinant Trypanosoma cruzi mucin-like antigen for serodiagnosis of Chagas' disease.
Javier G De Gaudenzi; Alberto C C Frasch; Griselda Noé; Vanina A Campo; Alejandro Cassola
Gene expression regulation in trypanosomatids.

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2012: M Eugenia Giorgi; Laura Ratier; Rosalía Agusti; Alberto C C Frasch; Rosa M de Lederkremer
Improved bioavailability of inhibitors of Trypanosoma cruzi trans-sialidase: PEGylation of lactose analogs with multiarm polyethyleneglycol.
Glycobiology 2012;22(10):1363-73.
2011: Claudia R De Marchi; Javier M Di Noia; Alberto C C Frasch; Igor Almeida; Vicente Amato Neto; Carlos A Buscaglia
Evaluation of a recombinant Trypanosoma cruzi mucin-like antigen for serodiagnosis of Chagas' disease.
Clinical and vaccine immunology : CVI 2011;18(11):1850-5.
2011: Javier G De Gaudenzi; Alberto C C Frasch; Griselda Noé; Vanina A Campo; Alejandro Cassola
Gene expression regulation in trypanosomatids.
Essays in biochemistry 2011;51():31-46.
2011: María Paula Zappia; Marcela Adriana Brocco; Silvia C Billi; Alberto C C Frasch; María Fernanda Ceriani
M6 membrane protein plays an essential role in Drosophila oogenesis.
PloS one 2011;6(5):e19715.
2010: M Eugenia Giorgi; Laura Ratier; Rosalía Agusti; Alberto C C Frasch; Rosa M de Lederkremer
Synthesis of PEGylated lactose analogs for inhibition studies on T.cruzi trans-sialidase.
Glycoconjugate journal 2010;27(5):549-59.
2010: Alejandro Cassola; Griselda Noé; Alberto C C Frasch
RNA recognition motifs involved in nuclear import of RNA-binding proteins.
RNA biology 2010;7(3):339-44.
2010: Marcela A Brocco; María Eugenia Fernández; Alberto C C Frasch
Filopodial protrusions induced by glycoprotein M6a exhibit high motility and aids synapse formation.
The European journal of neuroscience 2010;31(2):195-202.
2009: Alejandro Cassola; Alberto C C Frasch
An RNA recognition motif mediates the nucleocytoplasmic transport of a trypanosome RNA-binding protein.
The Journal of biological chemistry 2009;284(50):35015-28.
2009: Beata Fuchsova; María E Fernández; Julieta Alfonso; Alberto C C Frasch
Cysteine residues in the large extracellular loop (EC2) are essential for the function of the stress-regulated glycoprotein M6a.
The Journal of biological chemistry 2009;284(46):32075-88.
2008: Iben Damager; Sabrina Buchini; Maria F Amaya; Alejandro Buschiazzo; Pedro Alzari; Alberto C C Frasch; Andrew Watts; Stephen G Withers
Kinetic and mechanistic analysis of Trypanosoma cruzi trans-sialidase reveals a classical ping-pong mechanism with acid/base catalysis.
Biochemistry 2008;47(11):3507-12.
2008: Griselda Noé; Javier G De Gaudenzi; Alberto C C Frasch
Functionally related transcripts have common RNA motifs for specific RNA-binding proteins in trypanosomes.
BMC molecular biology 2008;9():107.
2008: Laura Ratier; Mariela Urrutia; Gaston Paris; Laura Zarebski; Alberto C C Frasch; Fernando A Goldbaum
Relevance of the diversity among members of the Trypanosoma cruzi trans-sialidase family analyzed with camelids single-domain antibodies.
PloS one 2008;3(10):e3524.
2007: Claudia Hartmann; Corinna Benz; Stefanie Brems; Louise Ellis; Van-Duc Luu; Mhairi Stewart; Iván D'Orso; Christian Busold; Kurt Fellenberg; Alberto C C Frasch; Mark Carrington; Jörg D Hoheisel; Christine E Clayton
Small trypanosome RNA-binding proteins TbUBP1 and TbUBP2 influence expression of F-box protein mRNAs in bloodstream trypanosomes.
Eukaryotic cell 2007;6(11):1964-78.
2007: Alejandro Cassola; Javier G De Gaudenzi; Alberto C C Frasch
Recruitment of mRNAs to cytoplasmic ribonucleoprotein granules in trypanosomes.
Molecular microbiology 2007;65(3):655-70.
2007: Adriana V Jäger; Javier G De Gaudenzi; Alejandro Cassola; Iván D'Orso; Alberto C C Frasch
mRNA maturation by two-step trans-splicing/polyadenylation processing in trypanosomes.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2035-42.
2006: Georgina N Montagna; John E Donelson; Alberto C C Frasch
Procyclic Trypanosoma brucei expresses separate sialidase and trans-sialidase enzymes on its surface membrane.
The Journal of biological chemistry 2006;281(45):33949-58.
2006: Marcela A Brocco; Alberto C C Frasch
Interfering polysialyltransferase ST8SiaII/STX mRNA inhibits neurite growth during early hippocampal development.
FEBS letters 2006;580(19):4723-6.
2006: Juan Mucci; Marikena G Risso; María Susana Leguizamón; Alberto C C Frasch; Oscar Campetella
The trans-sialidase from Trypanosoma cruzi triggers apoptosis by target cell sialylation.
Cellular microbiology 2006;8(7):1086-95.
2006: Björn Neubacher; Svenja Scheid; Soerge Kelm; Alberto C C Frasch; Bernd Meyer; Joachim Thiem
Synthesis of Neu5Ac oligosaccharides and analogues by transglycosylation and their binding properties as ligands to MAG.
Chembiochem : a European journal of chemical biology 2006;7(6):896-9.
2006: Carlos A Buscaglia; Vanina A Campo; Alberto C C Frasch; Javier Di noia
Trypanosoma cruzi surface mucins: host-dependent coat diversity.
Nature reviews. Microbiology 2006;4(3):229-36.
2006: Vanina A Campo; Carlos A Buscaglia; Javier Di noia; Alberto C C Frasch
Immunocharacterization of the mucin-type proteins from the intracellular stage of Trypanosoma cruzi.
Microbes and infection / Institut Pasteur 2006;8(2):401-9.
2006: Julieta Alfonso; Luciana R Frick; Dafne Magalí Silberman; María L Palumbo; Ana María Genaro; Alberto C C Frasch
Regulation of hippocampal gene expression is conserved in two species subjected to different stressors and antidepressant treatments.
Biological psychiatry 2006;59(3):244-51.
2005: Javier G De Gaudenzi; Alberto C C Frasch; Christine Clayton
RNA-binding domain proteins in Kinetoplastids: a comparative analysis.
Eukaryotic cell 2005;4(12):2106-14.
2005: Julieta Alfonso; María E Fernández; Benjamin Cooper; Gabriele Flugge; Alberto C C Frasch
The stress-regulated protein M6a is a key modulator for neurite outgrowth and filopodium/spine formation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(47):17196-201.
2005: Laurent Volpon; Iván D'Orso; Christopher R Young; Alberto C C Frasch; Kalle Gehring
NMR structural study of TcUBP1, a single RRM domain protein from Trypanosoma cruzi: contribution of a beta hairpin to RNA binding.
Biochemistry 2005;44(10):3708-17.
2005: Gaston Paris; Laura Ratier; María Fernanda Amaya; Tong Nguyen; Pedro Alzari; Alberto C C Frasch
A sialidase mutant displaying trans-sialidase activity.
Journal of molecular biology 2005;345(4):923-34.
2005: Julieta Alfonso; Alberto C C Frasch; Gabriele Flugge
Chronic stress, depression and antidepressants: effects on gene transcription in the hippocampus.
Reviews in the neurosciences 2005;16(1):43-56.
2005: Ileana C Cuevas; Alberto C C Frasch; Iván D'Orso
Insights into a CRM1-mediated RNA-nuclear export pathway in Trypanosoma cruzi.
Molecular and biochemical parasitology 2005;139(1):15-24.
2004: Julieta Alfonso; Fernán Agüero; Daniel O Sanchez; Gabriele Flugge; Eberhard Fuchs; Alberto C C Frasch; Guido D Pollevick
Gene expression analysis in the hippocampal formation of tree shrews chronically treated with cortisol.
Journal of neuroscience research 2004;78(5):702-10.
2004: Rosalía Agustí; Gastón París; Laura Ratier; Alberto C C Frasch; Rosa M de Lederkremer
Lactose derivatives are inhibitors of Trypanosoma cruzi trans-sialidase activity toward conventional substrates in vitro and in vivo.
Glycobiology 2004;14(7):659-70.
2004: María Fernanda Amaya; Andrew G Watts; Iben Damager; Annemarie Wehenkel; Tong Nguyen; Alejandro Buschiazzo; Gaston Paris; Alberto C C Frasch; Stephen G Withers; Pedro Alzari
Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase.
Structure (London, England : 1993) 2004;12(5):775-84.
2004: Carlos A Buscaglia; Vanina A Campo; Javier Di noia; Ana Cláudia T Torrecilhas; Cláudia R De Marchi; Michael A J Ferguson; Alberto C C Frasch; Igor Almeida
The surface coat of the mammal-dwelling infective trypomastigote stage of Trypanosoma cruzi is formed by highly diverse immunogenic mucins.
The Journal of biological chemistry 2004;279(16):15860-9.
2004: Julieta Alfonso; Guido D Pollevick; Marieke G Van Der Hart; Gabriele Flügge; Eberhard Fuchs; Alberto C C Frasch
Identification of genes regulated by chronic psychosocial stress and antidepressant treatment in the hippocampus.
The European journal of neuroscience 2004;19(3):659-66.
2004: Vanina A Campo; Javier Di noia; Carlos A Buscaglia; Fernán Agüero; Daniel O Sánchez; Alberto C C Frasch
Differential accumulation of mutations localized in particular domains of the mucin genes expressed in the vertebrate host stage of Trypanosoma cruzi.
Molecular and biochemical parasitology 2004;133(1):81-91.
2003: Marcela Brocco; Guido D Pollevick; Alberto C C Frasch
Differential regulation of polysialyltransferase expression during hippocampus development: Implications for neuronal survival.
Journal of neuroscience research 2003;74(5):744-53.
2003: Michael P Barrett; Richard J S Burchmore; August Stich; Julio O Lazzari; Alberto C C Frasch; Juan J Cazzulo; Sanjeev Krishna
The trypanosomiases.
Lancet 2003;362(9394):1469-80.
2003: Andrew G Watts; Iben Damager; Maria L Amaya; Alejandro Buschiazzo; Pedro Alzari; Alberto C C Frasch; Stephen G Withers
Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile.
Journal of the American Chemical Society 2003;125(25):7532-3.
2003: Javier G De Gaudenzi; Iván D'Orso; Alberto C C Frasch
RNA recognition motif-type RNA-binding proteins in Trypanosoma cruzi form a family involved in the interaction with specific transcripts in vivo.
The Journal of biological chemistry 2003;278(21):18884-94.
2003: Iván D'Orso; Javier G De Gaudenzi; Alberto C C Frasch
RNA-binding proteins and mRNA turnover in trypanosomes.
Trends in parasitology 2003;19(4):151-5.
2002: Iván D'Orso; Alberto C C Frasch
TcUBP-1, an mRNA destabilizing factor from trypanosomes, homodimerizes and interacts with novel AU-rich element- and Poly(A)-binding proteins forming a ribonucleoprotein complex.
The Journal of biological chemistry 2002;277(52):50520-8.
2002: Fernán Agüero; Vanina A Campo; Laura Cremona; Adriana Jäger; Javier Di noia; Peter Overath; Daniel O Sánchez; Alberto C C Frasch
Gene discovery in the freshwater fish parasite Trypanosoma carassii: identification of trans-sialidase-like and mucin-like genes.
Infection and immunity 2002;70(12):7140-4.
2002: Alejandro Buschiazzo; María Fernanda Amaya; Maria Laura Cremona; Alberto C C Frasch; Pedro Alzari
The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis.
Molecular cell 2002;10(4):757-68.
2002: Georgina Montagna; Maria Laura Cremona; Gaston Paris; María Fernanda Amaya; Alejandro Buschiazzo; Pedro Alzari; Alberto C C Frasch
The trans-sialidase from the african trypanosome Trypanosoma brucei.
European journal of biochemistry / FEBS 2002;269(12):2941-50.
2002: Javier Di noia; Carlos A Buscaglia; Claudia R De Marchi; Igor Almeida; Alberto C C Frasch
A Trypanosoma cruzi small surface molecule provides the first immunological evidence that Chagas' disease is due to a single parasite lineage.
The Journal of experimental medicine 2002;195(4):401-13.
2002: Julieta Alfonso; Guido D Pollevick; Anja Castensson; Elena Jazin; Alberto C C Frasch
Analysis of gene expression in the rat hippocampus using Real Time PCR reveals high inter-individual variation in mRNA expression levels.
Journal of neuroscience research 2002;67(2):225-34.
2002: Pablo F Argibay; Javier Di noia; Alejandra Hidalgo; Esteban Mocetti; Mariana Barbich; Alicia Susana Lorenti; Daniel Bustos; Monica L Tambutti; Sung Ho Hyon; Alberto C C Frasch; Daniel O Sánchez
Trypanosoma cruzi surface mucin TcMuc-e2 expressed on higher eukaryotic cells induces human T cell anergy, which is reversible.
Glycobiology 2002;12(1):25-32.
2001: Iván D'Orso; Alberto C C Frasch
TcUBP-1, a developmentally regulated U-rich RNA-binding protein involved in selective mRNA destabilization in trypanosomes.
The Journal of biological chemistry 2001;276(37):34801-9.
2001: Iván D'Orso; Alberto C C Frasch
Functionally different AU- and G-rich cis-elements confer developmentally regulated mRNA stability in Trypanosoma cruzi by interaction with specific RNA-binding proteins.
The Journal of biological chemistry 2001;276(19):15783-93.
2001: Gaston Paris; Maria Laura Cremona; María Fernanda Amaya; Alejandro Buschiazzo; S Giambiagi; Alberto C C Frasch; Pedro Alzari
Probing molecular function of trypanosomal sialidases: single point mutations can change substrate specificity and increase hydrolytic activity.
Glycobiology 2001;11(4):305-11.
2001: Daniel O Sánchez; Rubén Zandomeni; Silvio L Cravero; R E Verdún; E Pierrou; P Faccio; G Diaz; S Lanzavecchia; Fernán Agüero; Alberto C C Frasch; S G Andersson; Osvaldo Rossetti; O Grau; Rodolfo A Ugalde
Gene discovery through genomic sequencing of Brucella abortus.
Infection and immunity 2001;69(2):865-8.
2000: Fernán Agüero; R E Verdún; Alberto C C Frasch; Daniel O Sánchez
A random sequencing approach for the analysis of the Trypanosoma cruzi genome: general structure, large gene and repetitive DNA families, and gene discovery.
Genome research 2000;10(12):1996-2005.
2000: Guido D Pollevick; Javier Di noia; Maria Laura Salto; Carlos Lima; María Susana Leguizamón; Rosa M de Lederkremer; Alberto C C Frasch
Trypanosoma cruzi surface mucins with exposed variant epitopes.
The Journal of biological chemistry 2000;275(36):27671-80.
2000: Alberto C C Frasch
Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi.
Parasitology today (Personal ed.) 2000;16(7):282-6.
2000: Javier Di noia; Iván D'Orso; Daniel O Sánchez; Alberto C C Frasch
AU-rich elements in the 3'-untranslated region of a new mucin-type gene family of Trypanosoma cruzi confers mRNA instability and modulates translation efficiency.
The Journal of biological chemistry 2000;275(14):10218-27.
2000: Alejandro Buschiazzo; GA Tavares; Oscar Campetella; S Spinelli; Maria Laura Cremona; G París; María Fernanda Amaya; Alberto C C Frasch; Pedro Alzari
Structural basis of sialyltransferase activity in trypanosomal sialidases.
The EMBO journal 2000;19(1):16-24.
1999: Maria Laura Cremona; Oscar Campetella; Daniel O Sánchez; Alberto C C Frasch
Enzymically inactive members of the trans-sialidase family from Trypanosoma cruzi display beta-galactose binding activity.
Glycobiology 1999;9(6):581-7.
1999: Carlos A Buscaglia; Julieta Alfonso; Oscar Campetella; Alberto C C Frasch
Tandem amino acid repeats from Trypanosoma cruzi shed antigens increase the half-life of proteins in blood.
Blood 1999;93(6):2025-32.
1999: Alberto C C Frasch; Ramiro Verdun; Daniel O Sánchez
[Organization of the network for the study of the Trypanosoma cruzi genome].
Medicina 1999;59 Suppl 2():4-6.
1998: Rosalía Agusti; Alicia S Couto; Oscar Campetella; Alberto C C Frasch; Rosa M de Lederkremer
Structure of the glycosylphosphatidylinositol-anchor of the trans-sialidase from Trypanosoma cruzi metacyclic trypomastigote forms.
Molecular and biochemical parasitology 1998;97(1-2):123-31.
1998: Ramiro Verdun; N Di Paolo; Turan Urmenyi; Edson Rondinelli; Alberto C C Frasch; D O Sanchez
Gene discovery through expressed sequence Tag sequencing in Trypanosoma cruzi.
Infection and immunity 1998;66(11):5393-8.
1998: Diego COMERCI; Guido D Pollevick; AM Vigliocco; Alberto C C Frasch; Rodolfo A Ugalde
Vector development for the expression of foreign proteins in the vaccine strain Brucella abortus S19.
Infection and immunity 1998;66(8):3862-6.
1998: Javier Di noia; Iván D'Orso; Lena Aslund; Daniel O Sánchez; Alberto C C Frasch
The Trypanosoma cruzi mucin family is transcribed from hundreds of genes having hypervariable regions.
The Journal of biological chemistry 1998;273(18):10843-50.
1998: María Susana Leguizamón; Graciela Russomando; Antonieta Rojas de Arias; Margarita Samudio; M Cabral; Stella Maris González Cappa; Alberto C C Frasch; Oscar Campetella
Use of trans-Sialidase inhibition assay in a population serologically negative for Trypanosoma cruzi but at a high risk of infection.
Clinical and diagnostic laboratory immunology 1998;5(2):254-5.
1998: P Barderi; Oscar Campetella; Alberto C C Frasch; J A Santomé; Ulf Hellman; Ulf Pettersson; Juan J Cazzulo
The NADP+-linked glutamate dehydrogenase from Trypanosoma cruzi: sequence, genomic organization and expression.
The Biochemical journal 1998;330 ( Pt 2)():951-8.
1998: Carlos A Buscaglia; Oscar Campetella; María Susana Leguizamón; Alberto C C Frasch
The repetitive domain of Trypanosoma cruzi trans-sialidase enhances the immune response against the catalytic domain.
The Journal of infectious diseases 1998;177(2):431-6.
1997: Alejandro Buschiazzo; Oscar Campetella; Alberto C C Frasch
Trypanosoma rangeli sialidase: cloning, expression and similarity to T. cruzi trans-sialidase.
Glycobiology 1997;7(8):1167-73.
1997: Rosalía Agusti; Alicia S Couto; Oscar Campetella; Alberto C C Frasch; Rosa M de Lederkremer
The trans-sialidase of Trypanosoma cruzi is anchored by two different lipids.
Glycobiology 1997;7(6):731-5.
1997: María Susana Leguizamón; Graciela Russomando; Alejandro O Luquetti; A Rassi; M Almirón; Stella Maris González Cappa; Alberto C C Frasch; Oscar Campetella
Long-lasting antibodies detected by a trans-sialidase inhibition assay of sera from parasite-free, serologically cured chagasic patients.
The Journal of infectious diseases 1997;175(5):1272-5.
1996: Javier Di noia; G D Pollevick; M T Xavier; José O Previato; L Mendoça-Previato; Daniel O Sánchez; Alberto C C Frasch
High diversity in mucin genes and mucin molecules in Trypanosoma cruzi.
The Journal of biological chemistry 1996;271(50):32078-83.
1996: Carlos A Buscaglia; G D Pollevick; C Veloso; Myriam Lorca; Alberto C C Frasch; Daniel O Sánchez
A putative pyruvate dehydrogenase alpha subunit gene from Trypanosoma cruzi.
Biochimica et biophysica acta 1996;1309(1-2):53-7.
1996: J Hanke; Daniel O Sánchez; J Henriksson; Lena Aslund; U Pettersson; Alberto C C Frasch; Jörg D Hoheisel
Mapping the Trypanosoma cruzi genome: analyses of representative cosmid libraries.
BioTechniques 1996;21(4):686-8, 690-3.
1996: A Buschiazzo; Alberto C C Frasch; Oscar Campetella
Medium scale production and purification to homogeneity of a recombinant trans-sialidase from Trypanosoma cruzi.
Cellular and molecular biology (Noisy-le-Grand, France) 1996;42(5):703-10.
1996: Maria Laura Cremona; G D Pollevick; Alberto C C Frasch; Oscar Campetella
Effect of primary structure modifications in Trypanosoma cruzi neuraminidase/trans-sialidase activities.
Cellular and molecular biology (Noisy-le-Grand, France) 1996;42(5):697-702.
1995: Javier Di noia; Daniel O Sánchez; Alberto C C Frasch
The protozoan Trypanosoma cruzi has a family of genes resembling the mucin genes of mammalian cells.
The Journal of biological chemistry 1995;270(41):24146-9.
1995: Maria Laura Cremona; Daniel O Sánchez; Alberto C C Frasch; Oscar Campetella
A single tyrosine differentiates active and inactive Trypanosoma cruzi trans-sialidases.
Gene 1995;160(1):123-8.
1995: J Henriksson; B Porcel; M Rydåker; Andrés M Ruiz; Valeria Sabaj; Norbel Galanti; Juan J Cazzulo; Alberto C C Frasch; Ulf Pettersson
Chromosome specific markers reveal conserved linkage groups in spite of extensive chromosomal size variation in Trypanosoma cruzi.
Molecular and biochemical parasitology 1995;73(1-2):63-74.
1995: E E Jazin; E J Bontempi; D O Sanchez; Lena Aslund; J Henriksson; Alberto C C Frasch; Ulf Pettersson
Trypanosoma cruzi exoantigen is a member of a 160 kDa gene family.
Parasitology 1995;110 ( Pt 1)():61-9.
1994: María Susana Leguizamón; Oscar Campetella; Graciela Russomando; M Almiron; I Guillen; S M Ganzález Cappa; Alberto C C Frasch
Antibodies inhibiting Trypanosoma cruzi trans-sialidase activity in sera from human infections.
The Journal of infectious diseases 1994;170(6):1570-4.
1994: A C Pastini; S R Iglesias; V C Carricarte; M E Guerin; Daniel O Sánchez; Alberto C C Frasch
Immunoassay with recombinant Trypanosoma cruzi antigens potentially useful for screening donated blood and diagnosing Chagas disease.
Clinical chemistry 1994;40(10):1893-7.
1994: María Susana Leguizamón; Oscar Campetella; Stella Maris González Cappa; Alberto C C Frasch
Mice infected with Trypanosoma cruzi produce antibodies against the enzymatic domain of trans-sialidase that inhibit its activity.
Infection and immunity 1994;62(8):3441-6.
1994: P Varela; G D Pollevick; Marta Rivas; I Chinen; Norma Binsztein; Alberto C C Frasch; Rodolfo A Ugalde
Direct detection of Vibrio cholerae in stool samples.
Journal of clinical microbiology 1994;32(5):1246-8.
1994: Oscar Campetella; A D Uttaro; Armando J Parodi; Alberto C C Frasch
A recombinant Trypanosoma cruzi trans-sialidase lacking the amino acid repeats retains the enzymatic activity.
Molecular and biochemical parasitology 1994;64(2):337-40.
1994: M B Reyes; G D Pollevick; Alberto C C Frasch
An unusually small gene encoding a putative mucin-like glycoprotein in Trypanosoma cruzi.
Gene 1994;140(1):139-40.
1993: A Buschiazzo; Maria Laura Cremona; Oscar Campetella; Alberto C C Frasch; Daniel O Sánchez
Sequence of a Trypanosoma rangeli gene closely related to Trypanosoma cruzi trans-sialidase.
Molecular and biochemical parasitology 1993;62(1):115-6.
1993: G D Pollevick; D O Sanchez; Oscar Campetella; S Trombetta; M Sousa; J Henriksson; U Hellman; Ulf Pettersson; Juan J Cazzulo; Alberto C C Frasch
Members of the SAPA/trans-sialidase protein family have identical N-terminal sequences and a putative signal peptide.
Molecular and biochemical parasitology 1993;59(1):171-4.
1993: M A Ferrero-García; S E Trombetta; D O Sánchez; Angel Reglero; Alberto C C Frasch; Armando J Parodi
The action of Trypanosoma cruzi trans-sialidase on glycolipids and glycoproteins.
European journal of biochemistry / FEBS 1993;213(2):765-71.
1993: J Martínez; Oscar Campetella; Alberto C C Frasch; Juan J Cazzulo
The reactivity of sera from chagasic patients against different fragments of cruzipain, the major cysteine proteinase from Trypanosoma cruzi, suggests the presence of defined antigenic and catalytic domains.
Immunology letters 1993;35(2):191-6.
1993: P Varela; Marta Rivas; Norma Binsztein; Maria Laura Cremona; P Herrmann; Oscar R. Burrone; Rodolfo A Ugalde; Alberto C C Frasch
Identification of toxigenic Vibrio cholerae from the Argentine outbreak by PCR for ctx A1 and ctx A2-B.
FEBS letters 1993;315(1):74-6.
1992: Oscar Campetella; Daniel O Sánchez; Juan J Cazzulo; Alberto C C Frasch
A superfamily of Trypanosoma cruzi surface antigens.
Parasitology today (Personal ed.) 1992;8(11):378-81.
1992: Juan J Cazzulo; Alberto C C Frasch
SAPA/trans-sialidase and cruzipain: two antigens from Trypanosoma cruzi contain immunodominant but enzymatically inactive domains.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992;6(14):3259-64.
1992: A Buschiazzo; Oscar Campetella; R A Macina; S Salceda; Alberto C C Frasch; D O Sanchez
Sequence of the gene for a Trypanosoma cruzi protein antigenic during the chronic phase of human Chagas disease.
Molecular and biochemical parasitology 1992;54(1):125-8.
1992: G D Pollevick; S Giambiagi; S Mancardi; L de Luca; Oscar R. Burrone; Alberto C C Frasch; Rodolfo A Ugalde
Sex determination of bovine embryos by restriction fragment polymorphisms of PCR amplified ZFX/ZFY loci.
Bio/technology (Nature Publishing Company) 1992;10(7):805-7.
1992: Armando J Parodi; G D Pollevick; M Mautner; A Buschiazzo; D O Sanchez; Alberto C C Frasch
Identification of the gene(s) coding for the trans-sialidase of Trypanosoma cruzi.
The EMBO journal 1992;11(5):1705-10.
1992: Oscar Campetella; J Henriksson; Lena Aslund; Alberto C C Frasch; Ulf Pettersson; Juan J Cazzulo
The major cysteine proteinase (cruzipain) from Trypanosoma cruzi is encoded by multiple polymorphic tandemly organized genes located on different chromosomes.
Molecular and biochemical parasitology 1992;50(2):225-34.
1991: J Martinez; Oscar Campetella; Alberto C C Frasch; Juan J Cazzulo
The major cysteine proteinase (cruzipain) from Trypanosoma cruzi is antigenic in human infections.
Infection and immunity 1991;59(11):4275-7.
1991: U Vergara; Myriam Lorca; C Veloso; A Gonzalez; A Engstrom; Lena Aslund; U Pettersson; Alberto C C Frasch
Assay for detection of Trypanosoma cruzi antibodies in human sera based on reaction with synthetic peptides.
Journal of clinical microbiology 1991;29(9):2034-7.
1991: G D Pollevick; J L Affranchino; Alberto C C Frasch; Daniel O Sánchez
The complete sequence of a shed acute-phase antigen of Trypanosoma cruzi.
Molecular and biochemical parasitology 1991;47(2):247-50.
1991: Alberto C C Frasch; Juan J Cazzulo; Lena Aslund; U Pettersson
Comparison of genes encoding Trypanosoma cruzi antigens.
Parasitology today (Personal ed.) 1991;7(6):148-51.
1991: M S Leguizamon; Oscar Campetella; M B Reyes; C F Ibañez; M A Basombrio; J Rincon; A Orn; Alberto C C Frasch
Bloodstream Trypanosoma cruzi parasites from mice simultaneously express antigens that are markers of acute and chronic human Chagas disease.
Parasitology 1991;102 Pt 3():379-85.
1991: E E Jazín; Alejandro O Luquetti; Anis Rassi; Alberto C C Frasch
Shift of excretory-secretory immunogens of Trypanosoma cruzi during human Chagas' disease.
Infection and immunity 1991;59(6):2189-91.
1991: Lena Aslund; J Henriksson; Oscar Campetella; Alberto C C Frasch; Ulf Pettersson; Juan J Cazzulo
The C-terminal extension of the major cysteine proteinase (cruzipain) from Trypanosoma cruzi.
Molecular and biochemical parasitology 1991;45(2):345-7.
1991: J L Affranchino; G D Pollevick; Alberto C C Frasch
The expression of the major shed Trypanosoma cruzi antigen results from the developmentally-regulated transcription of a small gene family.
FEBS letters 1991;280(2):316-20.
1990: Alberto C C Frasch; Daniel O Sánchez; Juan J Cazzulo
Prospects of defined proteins for vaccine development.
Memórias do Instituto Oswaldo Cruz 1990;85(4):523-9.
1990: J Henriksson; Lena Aslund; R A Macina; B M Franke de Cazzulo; Juan J Cazzulo; Alberto C C Frasch; Ulf Pettersson
Chromosomal localization of seven cloned antigen genes provides evidence of diploidy and further demonstration of karyotype variability in Trypanosoma cruzi.
Molecular and biochemical parasitology 1990;42(2):213-23.
1990: Alberto C C Frasch; M B Reyes
Diagnosis of Chagas disease using recombinant DNA technology.
Parasitology today (Personal ed.) 1990;6(4):137-9.
1990: M B Reyes; Myriam Lorca; P Muñoz; Alberto C C Frasch
Fetal IgG specificities against Trypanosoma cruzi antigens in infected newborns.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(7):2846-50.
1989: Thaïs Souto-Padrón; M B Reyes; S Leguizamon; Oscar Campetella; Alberto C C Frasch; Wanderley de Souza
Trypanosoma cruzi proteins which are antigenic during human infections are located in defined regions of the parasite.
European journal of cell biology 1989;50(2):272-8.
1989: R A Macina; J L Affranchino; G D Pollevick; E E Jazin; Alberto C C Frasch
Variable number of repeat units in genes encoding Trypanosoma cruzi antigens.
FEBS letters 1989;257(2):365-8.
1989: J L Affranchino; C F Ibañez; Alejandro O Luquetti; Anis Rassi; M B Reyes; R A Macina; Lena Aslund; Ulf Pettersson; Alberto C C Frasch
Identification of a Trypanosoma cruzi antigen that is shed during the acute phase of Chagas' disease.
Molecular and biochemical parasitology 1989;34(3):221-8.
1988: Alberto C C Frasch; J L Affranchino; C F Ibañez; M B Reyes; R A Macina; Alejandro O Luquetti; Anis Rassi; Lena Aslund; Ulf Pettersson
Analysis of cloned Trypanosoma cruzi proteins that are antigenic during the acute and chronic phase of Chagas' disease.
Memórias do Instituto Oswaldo Cruz 1988;83 Suppl 1():345-6.
1988: C F Ibañez; J L Affranchino; R A Macina; M B Reyes; S Leguizamon; M E Camargo; Lena Aslund; Ulf Pettersson; Alberto C C Frasch
Multiple Trypanosoma cruzi antigens containing tandemly repeated amino acid sequence motifs.
Molecular and biochemical parasitology 1988;30(1):27-33.
1987: C F Ibañez; J L Affranchino; Alberto C C Frasch
Antigenic determinants of Trypanosoma cruzi defined by cloning of parasite DNA.
Molecular and biochemical parasitology 1987;25(2):175-84.
1987: R A Macina; S Arauzo; M B Reyes; D O Sanchez; M A Basombrio; E E Montamat; A Solari; Alberto C C Frasch
Trypanosoma cruzi isolates from Argentina and Chile grouped with the aid of DNA probes.
Molecular and biochemical parasitology 1987;25(1):45-53.
1986: J L Affranchino; D O Sanchez; J C Engel; Alberto C C Frasch; Andrés O M Stoppani
Trypanosoma cruzi: structure and transcription of kinetoplast DNA maxicircles of cloned stocks.
The Journal of protozoology 1986;33(4):503-7.
1986: R A Macina; D O Sanchez; D A Gluschankof; Oscar R. Burrone; Alberto C C Frasch
Sequence diversity in the kinetoplast DNA minicircles of Trypanosoma cruzi.
Molecular and biochemical parasitology 1986;21(1):25-32.
1985: R A Macina; D O Sanchez; J L Affranchino; J C Engel; Alberto C C Frasch
Polymorphisms within minicircle sequence classes in the kinetoplast DNA of Trypanosoma cruzi clones.
Molecular and biochemical parasitology 1985;16(1):61-74.
1985: S G Goijman; Alberto C C Frasch; Andrés O M Stoppani
Damage of Trypanosoma cruzi deoxyribonucleic acid by nitroheterocyclic drugs.
Biochemical pharmacology 1985;34(9):1457-61.
1984: D O Sanchez; R Madrid; J C Engel; Alberto C C Frasch
Rapid identification of Trypanosoma cruzi isolates by 'dot-spot' hybridization.
FEBS letters 1984;168(1):139-42.
1984: S G Goijman; Alberto C C Frasch; Andrés O M Stoppani
[Introduction of changes in the DNA of Trypanosoma cruzi by trypanocidal agents].
Revista Argentina de microbiología 1984;16(2):75-86.
1984: S G Goijman; Alberto C C Frasch; Andrés O M Stoppani
[Different effects of nifurtimox and benznidazole on the biosynthesis of DNA, RNA and proteins in Trypanosoma cruzi].
Medicina 1984;44(3):261-70.
1983: Alberto C C Frasch; A E Carrasco; S G Goijman; D O Sanchez
Repetitive sequences scattered throughout the genome of Trypanosoma cruzi.
Molecular and biochemical parasitology 1983;8(3):227-39.
1981: Alberto C C Frasch; S G Goijman; J J Cazzulo; Andrés O M Stoppani
Constant and variable regions in DNA mini-circles from Trypanosoma cruzi and Trypanosoma rangeli: application to species and stock differentiation.
Molecular and biochemical parasitology 1981;4(3-4):163-70.