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Nadja Fratzl-Zelman

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Physiology

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Bone Density

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Kamilla Nawrot-Wawrzyniak; Małgorzata Pańczyk-Tomaszewska; Paul Roschger; Helena Ziółkowska; Klaus Klaushofer; Barbara M Misof; Nadja Fratzl-Zelman
Changes in bone matrix mineralization after growth hormone treatment in children and adolescents with chronic kidney failure treated by dialysis: a paired biopsy study.
Nadja Fratzl-Zelman; Le T Duong; John E Fisher; Paul Roschger; Klaus Klaushofer
Effects of Odanacatib on bone mineralization density distribution in thoracic spine and femora of ovariectomized adult rhesus monkeys: a quantitative backscattered electron imaging study.
Roland Kocijan; Christian Muschitz; Angela Trubrich; Christina Bittighofer; Hans Peter Dimai; Nadja Fratzl-Zelman; Judith Haschka; Heinrich Resch
Femoral geometric parameters and BMD measurements by DXA in adult patients with different types of osteogenesis imperfecta.

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All Publications

2013: Kamilla Nawrot-Wawrzyniak; Małgorzata Pańczyk-Tomaszewska; Paul Roschger; Helena Ziółkowska; Klaus Klaushofer; Barbara M Misof; Nadja Fratzl-Zelman
Changes in bone matrix mineralization after growth hormone treatment in children and adolescents with chronic kidney failure treated by dialysis: a paired biopsy study.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2013;61(5):767-77.
2013: Nadja Fratzl-Zelman; Le T Duong; John E Fisher; Paul Roschger; Klaus Klaushofer
Effects of Odanacatib on bone mineralization density distribution in thoracic spine and femora of ovariectomized adult rhesus monkeys: a quantitative backscattered electron imaging study.
Calcified tissue international 2013;92(3):261-9.
2013: Roland Kocijan; Christian Muschitz; Angela Trubrich; Christina Bittighofer; Hans Peter Dimai; Nadja Fratzl-Zelman; Judith Haschka; Heinrich Resch
Femoral geometric parameters and BMD measurements by DXA in adult patients with different types of osteogenesis imperfecta.
Skeletal radiology 2013;42(2):187-94.
2013: B C J van der Eerden; Ulrich Zügel; René J M Bindels; Nadja Fratzl-Zelman; Joost G J Hoenderop; Klaus Klaushofer; Tom Nijenhuis; Paul Roschger; Andreas Steinmeyer; Johannes P T M van Leeuwen
The vitamin D analog ZK191784 normalizes decreased bone matrix mineralization in mice lacking the calcium channel TRPV5.
Journal of cellular physiology 2013;228(2):402-7.
2012: B C J van der Eerden; Petra Weissgerber; René J M Bindels; H Chiba; Teun J de Vries; Marco Eijken; Veit Flockerzi; Nadja Fratzl-Zelman; Marc Freichel; Joost G J Hoenderop; Klaus Klaushofer; Jenny Olausson; Paul Roschger; Marijke Schreuders-Koedam; Johannes P T M van Leeuwen
The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice.
Journal of cellular physiology 2012;227(5):1951-9.
2011: Christine Hamann; Ute Hempel; Veit Henkenjohann; Ricardo Bernhardt; Nadja Fratzl-Zelman; Claudia Goettsch; Klaus-Peter Günther; Jan Mettelsiefen; Stefan Rammelt; Martina Rauner; Paul Roschger; Lorenz C Hofbauer
Delayed bone regeneration and low bone mass in a rat model of insulin-resistant type 2 diabetes mellitus is due to impaired osteoblast function.
American journal of physiology. Endocrinology and metabolism 2011;301(6):E1220-8.
2011: Katarina Lindahl; Aileen M Barnes; Nadja Fratzl-Zelman; Michael P Whyte; Theresa E Hefferan; Elena Makareeva; Marina Brusel; Michael J Yaszemski; Carl-Johan Rubin; Andreas Kindmark; Paul Roschger; Klaus Klaushofer; William H McAlister; Steven Mumm; Sergey Leikin; Efrat Kessler; Adele L Boskey; Osten Ljunggren; Joan C Marini
COL1 C-propeptide cleavage site mutations cause high bone mass osteogenesis imperfecta.
Human mutation 2011;32(6):598-609.
2011: Nadja Fratzl-Zelman; Paul Roschger; Barbara M Misof; Kamilla Nawrot-Wawrzyniak; Sarah Pötter-Lang; Christian Muschitz; Heinrich Resch; Klaus Klaushofer; Elisabeth Zwettler
Fragility fractures in men with idiopathic osteoporosis are associated with undermineralization of the bone matrix without evidence of increased bone turnover.
Calcified tissue international 2011;88(5):378-87.
2010: Barbara M Misof; Eleftherios P Paschalis; Stéphane Blouin; Nadja Fratzl-Zelman; Klaus Klaushofer; Paul Roschger
Effects of 1 year of daily teriparatide treatment on iliacal bone mineralization density distribution (BMDD) in postmenopausal osteoporotic women previously treated with alendronate or risedronate.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(11):2297-303.
2010: Paul Roschger; Inderchand Manjubala; Norbert Zoeger; Florian Meirer; Rolf Simon; Chenghao Li; Nadja Fratzl-Zelman; Barbara M Misof; Eleftherios P Paschalis; Christina Streli; Peter Fratzl; Klaus Klaushofer
Bone material quality in transiliac bone biopsies of postmenopausal osteoporotic women after 3 years of strontium ranelate treatment.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(4):891-900.
2010: Roman Thaler; Silvia Spitzer; Monika Rumpler; Nadja Fratzl-Zelman; Klaus Klaushofer; Eleftherios P Paschalis; Franz Varga
Differential effects of homocysteine and beta aminopropionitrile on preosteoblastic MC3T3-E1 cells.
Bone 2010;46(3):703-9.
2010: Nadja Fratzl-Zelman; R Morello; B Lee; Frank Rauch; Francis H Glorieux; Barbara M Misof; Klaus Klaushofer; Paul Roschger
CRTAP deficiency leads to abnormally high bone matrix mineralization in a murine model and in children with osteogenesis imperfecta type VII.
Bone 2010;46(3):820-6.
2010: Paul Roschger; A Lombardi; B M Misof; G Maier; Nadja Fratzl-Zelman; Peter Fratzl; Klaus Klaushofer
Mineralization density distribution of postmenopausal osteoporotic bone is restored to normal after long-term alendronate treatment: qBEI and sSAXS data from the fracture intervention trial long-term extension (FLEX).
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(1):48-55.
2009: Nadja Fratzl-Zelman; Paul Roschger; Aurelien Gourrier; M Weber; Barbara M Misof; N Loveridge; J Reeve; Klaus Klaushofer; Peter Fratzl
Combination of nanoindentation and quantitative backscattered electron imaging revealed altered bone material properties associated with femoral neck fragility.
Calcified tissue international 2009;85(4):335-43.
2008: C Turecek; Nadja Fratzl-Zelman; M Rumpler; B Buchinger; S Spitzer; R Zoehrer; E Durchschlag; Klaus Klaushofer; Eleftherios P Paschalis; Franz Varga
Collagen cross-linking influences osteoblastic differentiation.
Calcified tissue international 2008;82(5):392-400.
2008: Paul Roschger; Nadja Fratzl-Zelman; Barbara M Misof; Francis H Glorieux; Klaus Klaushofer; Frank Rauch
Evidence that abnormal high bone mineralization in growing children with osteogenesis imperfecta is not associated with specific collagen mutations.
Calcified tissue international 2008;82(4):263-70.
2007: Peter Fratzl; Paul Roschger; Nadja Fratzl-Zelman; Eleftherios P Paschalis; Roger Phipps; Klaus Klaushofer
Evidence that treatment with risedronate in women with postmenopausal osteoporosis affects bone mineralization and bone volume.
Calcified tissue international 2007;81(2):73-80.
2006: Markus Weber; Paul Roschger; Nadja Fratzl-Zelman; Thomas Schöberl; Frank Rauch; Francis H Glorieux; Peter Fratzl; Klaus Klaushofer
Pamidronate does not adversely affect bone intrinsic material properties in children with osteogenesis imperfecta.
Bone 2006;39(3):616-22.
2005: Inderchand Manjubala; Alexander Woesz; Christine Pilz; Monika Rumpler; Nadja Fratzl-Zelman; Paul Roschger; Juergen Stampfl; Peter Fratzl
Biomimetic mineral-organic composite scaffolds with controlled internal architecture.
Journal of materials science. Materials in medicine 2005;16(12):1111-9.
2005: Angelika Valenta; Paul Roschger; Nadja Fratzl-Zelman; Paul J Kostenuik; Colin R Dunstan; Peter Fratzl; Klaus Klaushofer
Combined treatment with PTH (1-34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized rats.
Bone 2005;37(1):87-95.
2004: Nadja Fratzl-Zelman; Angelika Valenta; Paul Roschger; Alexander Nader; Bruce D Gelb; Peter Fratzl; Klaus Klaushofer
Decreased bone turnover and deterioration of bone structure in two cases of pycnodysostosis.
The Journal of clinical endocrinology and metabolism 2004;89(4):1538-47.
2003: Himadri S Gupta; Paul Roschger; I Zizak; Nadja Fratzl-Zelman; Alexander Nader; Klaus Klaushofer; Peter Fratzl
Mineralized microstructure of calcified avian tendons: a scanning small angle X-ray scattering study.
Calcified tissue international 2003;72(5):567-76.
2003: Nadja Fratzl-Zelman; Helmut Glantschnig; Monika Rumpler; Alexander Nader; Adolf Ellinger; Franz Varga
The expression of matrix metalloproteinase-13 and osteocalcin in mouse osteoblasts is related to osteoblastic differentiation and is modulated by 1,25-dihydroxyvitamin D3 and thyroid hormones.
Cell biology international 2003;27(6):459-68.
2003: Walter Tesch; T VandenBos; P Roschgr; Nadja Fratzl-Zelman; Klaus Klaushofer; Wouter Beertsen; Peter Fratzl
Orientation of mineral crystallites and mineral density during skeletal development in mice deficient in tissue nonspecific alkaline phosphatase.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(1):117-25.
1999: Franz Varga; Eva Luegmayr; Nadja Fratzl-Zelman; Helmut Glantschnig; Adolf Ellinger; D Prinz; Monika Rumpler; Klaus Klaushofer
Tri-iodothyronine inhibits multilayer formation of the osteoblastic cell line, MC3T3-E1, by promoting apoptosis.
The Journal of endocrinology 1999;160(1):57-65.
1998: Nadja Fratzl-Zelman; Peter Fratzl; H Hörandner; BM Grabner; Franz Varga; Adolf Ellinger; Klaus Klaushofer
Matrix mineralization in MC3T3-E1 cell cultures initiated by beta-glycerophosphate pulse.
Bone 1998;23(6):511-20.
1998: Eva Luegmayr; Franz Varga; Helmut Glantschnig; Nadja Fratzl-Zelman; Monika Rumpler; Adolf Ellinger; Klaus Klaushofer
1,25-Dihydroxy vitamin D3 and tri-iodothyronine stimulate the expression of a protein immunologically related to osteocalcin.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(4):477-86.
1997: Franz Varga; Monika Rumpler; Eva Luegmayr; Nadja Fratzl-Zelman; Helmut Glantschnig; Klaus Klaushofer
Triiodothyronine, a regulator of osteoblastic differentiation: depression of histone H4, attenuation of c-fos/c-jun, and induction of osteocalcin expression.
Calcified tissue international 1997;61(5):404-11.
1997: Nadja Fratzl-Zelman; H Hörandner; Eva Luegmayr; Franz Varga; Adolf Ellinger; M P Erlee; Klaus Klaushofer
Effects of triiodothyronine on the morphology of cells and matrix, the localization of alkaline phosphatase, and the frequency of apoptosis in long-term cultures of MC3T3-E1 cells.
Bone 1997;20(3):225-36.
1995: Klaus Klaushofer; Franz Varga; Helmut Glantschnig; Nadja Fratzl-Zelman; E Czerwenka; Hans Jörg Leis; K Koller; Meinrad Peterlik
The regulatory role of thyroid hormones in bone cell growth and differentiation.
The Journal of nutrition 1995;125(7 Suppl):1996S-2003S.
1993: Peter Fratzl; Nadja Fratzl-Zelman; Klaus Klaushofer
Collagen packing and mineralization. An x-ray scattering investigation of turkey leg tendon.
Biophysical journal 1993;64(1):260-6.
1992: Peter Fratzl; M Groschner; G Vogl; Hanns Plenk; J Eschberger; Nadja Fratzl-Zelman; K Koller; Klaus Klaushofer
Mineral crystals in calcified tissues: a comparative study by SAXS.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(3):329-34.
1991: Peter Fratzl; Nadja Fratzl-Zelman; Klaus Klaushofer; G Vogl; K Koller
Nucleation and growth of mineral crystals in bone studied by small-angle X-ray scattering.
Calcified tissue international 1991;48(6):407-13.
1990: Hans Jörg Leis; Ernst Malle; O Hoffmann; Klaus Klaushofer; Nadja Fratzl-Zelman; K Koller; Meinrad Peterlik
Experimental considerations on the measurement of prostaglandins during long-time incubations of neonatal mouse calvaria.
Biochemical and biophysical research communications 1990;169(2):545-50.
1989: Klaus Klaushofer; O Hoffmann; H Hörandner; S Karasegh; Nadja Fratzl-Zelman; Hans Jörg Leis; H Gleispach; K Koller; Meinrad Peterlik
Effect of auranofin on resorption, prostaglandin synthesis and ultrastructure of bone cells in cultured mouse calvaria.
The Journal of rheumatology 1989;16(6):749-56.