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Kenneth Frauwirth

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Paúl E Clavijo; Kenneth A Frauwirth
Anergic CD8+ T lymphocytes have impaired NF-κB activation with defects in p65 phosphorylation and acetylation.
Erikka L Carr; Alina Kelman; Glendon S Wu; Ravindra Gopaul; Emilee Senkevitch; Anahit Aghvanyan; Achmed M Turay; Kenneth A Frauwirth
Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation.
Aimee J Marko; Rebecca A Miller; Alina Kelman; Kenneth A Frauwirth
Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling.

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All Publications

2012: Paúl E Clavijo; Kenneth A Frauwirth
Anergic CD8+ T lymphocytes have impaired NF-κB activation with defects in p65 phosphorylation and acetylation.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(3):1213-21.
2010: Erikka L Carr; Alina Kelman; Glendon S Wu; Ravindra Gopaul; Emilee Senkevitch; Anahit Aghvanyan; Achmed M Turay; Kenneth A Frauwirth
Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(2):1037-44.
2010: Aimee J Marko; Rebecca A Miller; Alina Kelman; Kenneth A Frauwirth
Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling.
PloS one 2010;5(11):e15425.
2009: Mathangi Srinivasan; Kenneth A Frauwirth
Peripheral tolerance in CD8+ T cells.
Cytokine 2009;46(2):147-59.
2007: Mathangi Srinivasan; Kenneth A Frauwirth
Reciprocal NFAT1 and NFAT2 nuclear localization in CD8+ anergic T cells is regulated by suboptimal calcium signaling.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(6):3734-41.
2007: Russell G Jones; Thi Bui; Carl White; Muniswamy Madesh; Connie M Krawczyk; Tullia Lindsten; Brian Hawkins; Sara Kubek; Kenneth A Frauwirth; Y Lynn Wang; Stuart Conway; H Llewelyn Roderick; Martin D Bootman; Hao Shen; J Kevin Foskett; Craig Thompson
The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis.
Immunity 2007;27(2):268-80.
2006: Justin P Edwards; Xia Zhang; Kenneth A Frauwirth; David Mosser
Biochemical and functional characterization of three activated macrophage populations.
Journal of leukocyte biology 2006;80(6):1298-307.
2005: Richard V Parry; Jens M Chemnitz; Kenneth A Frauwirth; Anthony R Lanfranco; Inbal Braunstein; Sumire V Kobayashi; Peter Linsley; Craig Thompson; James L Riley
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms.
Molecular and cellular biology 2005;25(21):9543-53.
2004: Kenneth A Frauwirth; Craig Thompson
Regulation of T lymphocyte metabolism.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(8):4661-5.
2004: Tom Li Stephen; Fabian Benencia; Maria C Courreges; Phyllis A Gimotty; Eugene Khang; Ronald J Buckanovich; Kenneth A Frauwirth; Lin Zhang; Dionyssios Katsaros; Craig Thompson; Bruce Levine; George Coukos
Ovarian carcinoma expresses the NKG2D ligand Letal and promotes the survival and expansion of CD28- antitumor T cells.
Cancer research 2004;64(6):2175-82.
2002: Y Lynn Wang; Kenneth A Frauwirth; Shamina M Rangwala; Mitchell Lazar; Craig Thompson
Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival.
The Journal of biological chemistry 2002;277(35):31781-8.
2002: Kenneth A Frauwirth; James L Riley; Marian H Harris; Richard V Parry; Jeffrey C Rathmell; David Plas; Rebecca L Elstrom; Carl H June; Craig Thompson
The CD28 signaling pathway regulates glucose metabolism.
Immunity 2002;16(6):769-77.
2002: Kenneth A Frauwirth; Craig Thompson
Activation and inhibition of lymphocytes by costimulation.
The Journal of clinical investigation 2002;109(3):295-9.
2001: Maria-Luisa Alegre; Kenneth A Frauwirth; Craig Thompson
T-cell regulation by CD28 and CTLA-4.
Nature reviews. Immunology 2001;1(3):220-8.
2001: Kenneth A Frauwirth; Maria-Luisa Alegre; Craig Thompson
CTLA-4 is not required for induction of CD8(+) T cell anergy in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):4936-41.
2001: M Alegre; Francesca Fallarino; Ping Zhou; Kenneth A Frauwirth; J Richard Thistlethwaite; K Newell; Thomas F Gajewski; Jeffrey A Bluestone
Transplantation and the CD28/CTLA4/B7 pathway.
Transplantation proceedings 2001;33(1-2):209-11.
2000: Tullia Lindsten; AJ Ross; A King; Wei-Xing Zong; Jeffrey C Rathmell; HA Shiels; E Ulrich; Katrina G Waymire; Patryce L Mahar; Kenneth A Frauwirth; Youhai Chen; Michael Wei; V M Eng; David M Adelman; M Celeste Simon; A Ma; Jeffrey A Golden; Gerard I Evan; Stanley J Korsmeyer; Grant R MacGregor; Craig Thompson
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.
Molecular cell 2000;6(6):1389-99.
2000: Jeffrey C Rathmell; Matthew G Vander Heiden; Marian H Harris; Kenneth A Frauwirth; Craig Thompson
In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability.
Molecular cell 2000;6(3):683-92.
2000: Kenneth A Frauwirth; Maria-Luisa Alegre; Craig Thompson
Induction of T cell anergy in the absence of CTLA-4/B7 interaction.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):2987-93.
1999: Craig Thompson; Jeffrey C Rathmell; Kenneth A Frauwirth; Tullia Lindsten; Charles Rudin; Joseph T Opferman; Philip G Ashton-Rickardt; Marian H Harris; Navdeep S Chandel; Paul T Schumacker; Matthew G Vander Heiden
What keeps a resting T cell alive?
Cold Spring Harbor symposia on quantitative biology 1999;64():383-7.