Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Bertil Fredholm

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Anatomy

Procedures

Autoradiography

Concepts & Ideas

Drug Dose-Response Relationship

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
31
Svenningsson, Per
19
Johansson, Björn
15
Kull, Björn
12
Jondal, Mikael
11
Halldner, Linda
11
Lindström, Karin
11
Schulte, Gunnar
10
Nordstedt, C
9
Arslan, Giulia
8
Daré, Elisabetta
8
Fisone, Gilberto
7
Chen, Jiang-Fan
7
Greengard, Paul
6
Lindskog, Maria
6
Le Moine, Catherine

Sign-in to see all Coauthors

Publications

TOP 3
Maggi Laura; Trettel Flavia; Scianni Maria; Bertollini Cristina; Eusebi Fabrizio; Fredholm Bertil B; Limatola Cristina
LTP impairment by fractalkine/CX3CL1 in mouse hippocampus is mediated through the activity of adenosine receptor type 3 (A3R).
Salehi Albert; Parandeh Fariborz; Fredholm Bertil B; Grapengiesser Eva; Hellman Bo
Absence of adenosine A1 receptors unmasks pulses of insulin release and prolongs those of glucagon and somatostatin.
Yu Liqun; Coelho Joana E; Zhang Xiaoling; Fu Yutao; Tillman Abigail; Karaoz Ulas; Fredholm Bertil B; Weng Zhiping; Chen Jiang-Fan
Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profiling.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Bertil Fredholm (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Maggi Laura; Trettel Flavia; Scianni Maria; Bertollini Cristina; Eusebi Fabrizio; Fredholm Bertil B; Limatola Cristina
LTP impairment by fractalkine/CX3CL1 in mouse hippocampus is mediated through the activity of adenosine receptor type 3 (A3R).
Journal of neuroimmunology 2009;215(1-2):36-42.
2009: Salehi Albert; Parandeh Fariborz; Fredholm Bertil B; Grapengiesser Eva; Hellman Bo
Absence of adenosine A1 receptors unmasks pulses of insulin release and prolongs those of glucagon and somatostatin.
Life sciences 2009;85(11-12):470-6.
2009: Yu Liqun; Coelho Joana E; Zhang Xiaoling; Fu Yutao; Tillman Abigail; Karaoz Ulas; Fredholm Bertil B; Weng Zhiping; Chen Jiang-Fan
Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profiling.
Physiological genomics 2009;37(3):199-210.
2009: Yang Jiang-Ning; Chen Jiang-Fan; Fredholm Bertil B
Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine.
American journal of physiology. Heart and circulatory physiology 2009;296(4):H1141-9.
2009: Conte Carmela; Grottelli Silvia; Prudenzi Elvira; Bellezza Ilaria; Fredholm Bertil B; Minelli Alba
A(1) and A(3) adenosine receptors alter glutathione status in an organ-specific manner and influence the changes after inhibition of gamma-glutamylcysteine ligase.
Free radical research 2009;43(3):304-11.
2009: Yang Jiang-Ning; Björklund Olga; Lindström-Törnqvist Karin; Lindgren Eva; Eriksson Therese M; Kahlström Johan; Chen Jiang-Fan; Schwarzschild Michael A; Tobler Irene; Fredholm Bertil B
Mice heterozygous for both A1 and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine.
Journal of applied physiology (Bethesda, Md. : 1985) 2009;106(2):631-9.
2008: Björklund Olga; Halldner-Henriksson Linda; Yang Jiangning; Eriksson Therese M; Jacobson Marlene A; Daré Elisabetta; Fredholm Bertil B
Decreased behavioral activation following caffeine, amphetamine and darkness in A3 adenosine receptor knock-out mice.
Physiology & behavior 2008;95(5):668-76.
2008: Johansson Stina M; Lindgren Eva; Yang Jiang-Ning; Herling Andreas W; Fredholm Bertil B
Adenosine A1 receptors regulate lipolysis and lipogenesis in mouse adipose tissue-interactions with insulin.
European journal of pharmacology 2008;597(1-3):92-101.
2008: Björklund Olga; Shang Mingmei; Tonazzini Ilaria; Daré Elisabetta; Fredholm Bertil B
Adenosine A1 and A3 receptors protect astrocytes from hypoxic damage.
European journal of pharmacology 2008;596(1-3):6-13.
2008: Roseti Cristina; Martinello Katiuscia; Fucile Sergio; Piccari Vanessa; Mascia Addolorata; Di Gennaro Giancarlo; Quarato Pier Paolo; Manfredi Mario; Esposito Vincenzo; Cantore Gianpaolo; Arcella Antonella; Simonato Michele; Fredholm Bertil B; Limatola Cristina; Miledi Ricardo; Eusebi Fabrizio
Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):15118-23.
2008: Brand Frank; Klutz Athena M; Jacobson Kenneth A; Fredholm Bertil B; Schulte Gunnar
Adenosine A(2A) receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC.
European journal of pharmacology 2008;590(1-3):36-42.
2008: Sawynok Jana; Reid Allison R; Fredholm Bertil B
Caffeine reverses antinociception by amitriptyline in wild type mice but not in those lacking adenosine A1 receptors.
Neuroscience letters 2008;440(2):181-4.
2008: Hua Xiaoyang; Chason Kelly D; Fredholm Bertil B; Deshpande Deepak A; Penn Raymond B; Tilley Stephen L
Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells.
The Journal of allergy and clinical immunology 2008;122(1):107-13, 113.e1-7.
2008: Chen Liying; Fredholm Bertil B; Jondal Mikael
Adenosine, through the A1 receptor, inhibits vesicular MHC class I cross-presentation by resting DC.
Molecular immunology 2008;45(8):2247-54.
2008: Minelli Alba; Bellezza Ilaria; Collodel Giulia; Fredholm Bertil B
Promiscuous coupling and involvement of protein kinase C and extracellular signal-regulated kinase 1/2 in the adenosine A1 receptor signalling in mammalian spermatozoa.
Biochemical pharmacology 2008;75(4):931-41.
2007: Ohta Akio; Lukashev Dmitriy; Jackson Edwin K; Fredholm Bertil B; Sitkovsky Michail
1,3,7-trimethylxanthine (caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7431-8.
2007: Johansson Stina M; Salehi Albert; Sandström Marie E; Westerblad Håkan; Lundquist Ingmar; Carlsson Per-Ola; Fredholm Bertil B; Katz Abram
A1 receptor deficiency causes increased insulin and glucagon secretion in mice.
Biochemical pharmacology 2007;74(11):1628-35.
2007: Fredholm Bertil B; Chern Yijuang; Franco Rafael; Sitkovsky Michail
Aspects of the general biology of adenosine A2A signaling.
Progress in neurobiology 2007;83(5):263-76.
2007: Li Tianfu; Quan Lan Jing; Fredholm Bertil B; Simon Roger P; Boison Detlev
Adenosine dysfunction in astrogliosis: cause for seizure generation?
Neuron glia biology 2007;3(4):353-66.
2007: Björklund Olga; Kahlström Johan; Salmi Peter; Ogren Sven Ove; Vahter Marie; Chen Jiang-Fan; Fredholm Bertil B; Daré Elisabetta
The effects of methylmercury on motor activity are sex- and age-dependent, and modulated by genetic deletion of adenosine receptors and caffeine administration.
Toxicology 2007;241(3):119-33.
2007: Daré Elisabetta; Schulte Gunnar; Karovic Olga; Hammarberg Christian; Fredholm Bertil B
Modulation of glial cell functions by adenosine receptors.
Physiology & behavior 2007;92(1-2):15-20.
2007: Sällström J; Carlsson P-O; Fredholm B B; Larsson E; Persson A E G; Palm F
Diabetes-induced hyperfiltration in adenosine A(1)-receptor deficient mice lacking the tubuloglomerular feedback mechanism.
Acta physiologica (Oxford, England) 2007;190(3):253-9.
2007: Fredholm B B
Adenosine, an endogenous distress signal, modulates tissue damage and repair.
Cell death and differentiation 2007;14(7):1315-23.
2007: Wendler Christopher C; Amatya Salina; McClaskey Carolyn; Ghatpande Satish; Fredholm Bertil B; Rivkees Scott A
A1 adenosine receptors play an essential role in protecting the embryo against hypoxia.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9697-702.
2007: Tabata Toshihide; Kawakami Daisuke; Hashimoto Kouichi; Kassai Hidetoshi; Yoshida Takayuki; Hashimotodani Yuki; Fredholm Bertil B; Sekino Yuko; Aiba Atsu; Kano Masanobu
G protein-independent neuromodulatory action of adenosine on metabotropic glutamate signalling in mouse cerebellar Purkinje cells.
The Journal of physiology 2007;581(Pt 2):693-708.
2007: Johansson S M; Yang J-N; Lindgren E; Fredholm B B
Eliminating the antilipolytic adenosine A1 receptor does not lead to compensatory changes in the antilipolytic actions of PGE2 and nicotinic acid.
Acta physiologica (Oxford, England) 2007;190(1):87-96.
2007: Yang J-N; Tiselius C; Daré E; Johansson B; Valen G; Fredholm B B
Sex differences in mouse heart rate and body temperature and in their regulation by adenosine A1 receptors.
Acta physiologica (Oxford, England) 2007;190(1):63-75.
2007: Fredholm B B; Hökfelt T; Milligan G
G-protein-coupled receptors: an update.
Acta physiologica (Oxford, England) 2007;190(1):3-7.
2007: Karovic Olga; Tonazzini Ilaria; Rebola Nelson; Edström Erik; Lövdahl Cecilia; Fredholm Bertil B; Daré Elisabetta
Toxic effects of cobalt in primary cultures of mouse astrocytes. Similarities with hypoxia and role of HIF-1alpha.
Biochemical pharmacology 2007;73(5):694-708.
2006: Lai E Y; Patzak A; Steege A; Mrowka R; Brown R; Spielmann N; Persson P B; Fredholm B B; Persson A E G
Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction.
Kidney international 2006;70(4):690-8.
2006: Schotanus Sietske M; Fredholm Bertil B; Chergui Karima
NMDA depresses glutamatergic synaptic transmission in the striatum through the activation of adenosine A1 receptors: evidence from knockout mice.
Neuropharmacology 2006;51(2):272-82.
2006: Fedele Denise E; Li Tianfu; Lan Jing Q; Fredholm Bertil B; Boison Detlev
Adenosine A1 receptors are crucial in keeping an epileptic focus localized.
Experimental neurology 2006;200(1):184-90.
2006: Wu Wei-Ping; Hao Jing-Xia; Fredholm Bertil B; Wiesenfeld-Hallin Zsuzsanna; Xu Xiao-Jun
Effect of acute and chronic administration of caffeine on pain-like behaviors in rats with partial sciatic nerve injury.
Neuroscience letters 2006;402(1-2):164-6.
2006: Brown Russell D; Thorén Peter; Steege Andreas; Mrowka Ralf; Sällström Johan; Skøtt Ole; Fredholm Bertil B; Persson A Erik G
Influence of the adenosine A1 receptor on blood pressure regulation and renin release.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(5):R1324-9.
2006: Jonsson Malin; Dabrowski Michael; Gurley David A; Larsson Olof; Johnson Edwin C; Fredholm Bertil B; Eriksson Lars I
Activation and inhibition of human muscular and neuronal nicotinic acetylcholine receptors by succinylcholine.
Anesthesiology 2006;104(4):724-33.
2006: Lankford Amy R; Yang Jiang-Ning; Rose'Meyer Roselyn; French Brent A; Matherne G Paul; Fredholm Bertil B; Yang Zequan
Effect of modulating cardiac A1 adenosine receptor expression on protection with ischemic preconditioning.
American journal of physiology. Heart and circulatory physiology 2006;290(4):H1469-73.
2006: Kuzmin Alexander; Johansson Björn; Gimenez Lydia; Ogren Sven-Ove; Fredholm Bertil B
Combination of adenosine A1 and A2A receptor blocking agents induces caffeine-like locomotor stimulation in mice.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2006;16(2):129-36.
2005: Nergårdh R; Oerther S; Fredholm B B
Differences between A 68930 and SKF 82958 could suggest synergistic roles of D1 and D5 receptors.
Pharmacology, biochemistry, and behavior 2005;82(3):495-505.
2005: Kim Mina; Yu Zhao-Xue; Fredholm Bertil B; Rivkees Scott A
Susceptibility of the developing brain to acute hypoglycemia involving A1 adenosine receptor activation.
American journal of physiology. Endocrinology and metabolism 2005;289(4):E562-9.
2005: Andersson Mikael; Usiello Alessandro; Borgkvist Anders; Pozzi Laura; Dominguez Cecilia; Fienberg Allen A; Svenningsson Per; Fredholm Bertil B; Borrelli Emiliana; Greengard Paul; Fisone Gilberto
Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(37):8432-8.
2005: Johansson Stina; Fredholm Bertil B; Hjort Charlotta; Morein Torbjörn; Kull Björn; Hu Ping-Sheng
Evidence against adenosine analogues being agonists at the growth hormone secretagogue receptor.
Biochemical pharmacology 2005;70(4):598-605.
2005: Huang Zhi-Li; Qu Wei-Min; Eguchi Naomi; Chen Jiang-Fan; Schwarzschild Michael A; Fredholm Bertil B; Urade Yoshihiro; Hayaishi Osamu
Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine.
Nature neuroscience 2005;8(7):858-9.
2005: Giménez-Llort Lydia; Masino Susan A; Diao Lihong; Fernández-Teruel Alberto; Tobeña Adolf; Halldner Linda; Fredholm Bertil B
Mice lacking the adenosine A1 receptor have normal spatial learning and plasticity in the CA1 region of the hippocampus, but they habituate more slowly.
Synapse (New York, N.Y.) 2005;57(1):8-16.
2005: Ghanem Esam; Lövdahl Cecilia; Daré Elisabetta; Ledent Catherine; Fredholm Bertil B; Boeynaems Jean-Marie; Van Driessche Willy; Beauwens Renaud
Luminal adenosine stimulates chloride secretion through A1 receptor in mouse jejunum.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(5):G972-7.
2005: Kukley Maria; Schwan Maximilian; Fredholm Bertil B; Dietrich Dirk
The role of extracellular adenosine in regulating mossy fiber synaptic plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(11):2832-7.
2005: Wu Wei-Ping; Hao Jing-Xia; Halldner Linda; Lövdahl Cecilia; DeLander Gary E; Wiesenfeld-Hallin Zsuzsanna; Fredholm Bertil B; Xu Xiao-Jun
Increased nociceptive response in mice lacking the adenosine A1 receptor.
Pain 2005;113(3):395-404.
2005: Salmi Peter; Chergui Karima; Fredholm Bertil B
Adenosine-dopamine interactions revealed in knockout mice.
Journal of molecular neuroscience : MN 2005;26(2-3):239-44.
2005: Fredholm Bertil B; Chen Jiang-Fan; Masino Susan A; Vaugeois Jean-Marie
Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs.
Annual review of pharmacology and toxicology 2005;45():385-412.
2005: Fredholm Bertil B; Chen Jiang-Fan; Cunha Rodrigo A; Svenningsson Per; Vaugeois Jean-Marie
Adenosine and brain function.
International review of neurobiology 2005;63():191-270.
2004: Schulte G; Sommerschild H; Yang J; Tokuno S; Goiny M; Lövdahl C; Johansson B; Fredholm B B; Valen G
Adenosine A receptors are necessary for protection of the murine heart by remote, delayed adaptation to ischaemia.
Acta physiologica Scandinavica 2004;182(2):133-43.
2004: Halldner Linda; Lopes Luisa V; Daré Elisabetta; Lindström Karin; Johansson Björn; Ledent Catherine; Cunha Rodrigo A; Fredholm Bertil B
Binding of adenosine receptor ligands to brain of adenosine receptor knock-out mice: evidence that CGS 21680 binds to A1 receptors in hippocampus.
Naunyn-Schmiedeberg's archives of pharmacology 2004;370(4):270-8.
2004: Olsson Tomas; Cronberg Tobias; Rytter Anna; Asztély Fredrik; Fredholm Bertil B; Smith Maj-Lis; Wieloch Tadeusz
Deletion of the adenosine A1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro.
The European journal of neuroscience 2004;20(5):1197-204.
2004: Fredholm Bertil B
[Connection between caffeine, adenosine receptors and dopamine. Coffee reduces the risk of Parkinson disease]
Läkartidningen 2004;101(34):2552-5.
2004: Jonsson Malin; Wyon Nicholas; Lindahl Sten G E; Fredholm Bertil B; Eriksson Lars I
Neuromuscular blocking agents block carotid body neuronal nicotinic acetylcholine receptors.
European journal of pharmacology 2004;497(2):173-80.
2004: Halldner Linda; Adén Ulrika; Dahlberg Viktoria; Johansson Björn; Ledent Catherine; Fredholm Bertil B
The adenosine A1 receptor contributes to the stimulatory, but not the inhibitory effect of caffeine on locomotion: a study in mice lacking adenosine A1 and/or A2A receptors.
Neuropharmacology 2004;46(7):1008-17.
2004: Lopes Luísa V; Halldner Linda; Rebola Nelson; Johansson Björn; Ledent Catherine; Chen Jian Fan; Fredholm Bertil B; Cunha Rodrigo A
Binding of the prototypical adenosine A(2A) receptor agonist CGS 21680 to the cerebral cortex of adenosine A(1) and A(2A) receptor knockout mice.
British journal of pharmacology 2004;141(6):1006-14.
2004: Minelli Alba; Liguori Lavinia; Bellazza Ilaria; Mannucci Roberta; Johansson Björn; Fredholm Bertil B
Involvement of A1 adenosine receptors in the acquisition of fertilizing capacity.
Journal of andrology 2004;25(2):286-92.
2004: Hammarberg Christian; Fredholm Bertil B; Schulte Gunnar
Adenosine A3 receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-3'-kinase.
Biochemical pharmacology 2004;67(1):129-34.
2003: Svenningsson Per; Fredholm Bertil B
Exciting news about A2A receptors.
Neurology 2003;61(11 Suppl 6):S10-1.
2003: Fredholm Bertil B; Svenningsson Per
Adenosine-dopamine interactions: development of a concept and some comments on therapeutic possibilities.
Neurology 2003;61(11 Suppl 6):S5-9.
2003: Stenberg Dag; Litonius Erik; Halldner Linda; Johansson Björn; Fredholm Bertil B; Porkka-Heiskanen Tarja
Sleep and its homeostatic regulation in mice lacking the adenosine A1 receptor.
Journal of sleep research 2003;12(4):283-90.
2003: Schulte Gunnar; Fredholm Bertil B
The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38.
Experimental cell research 2003;290(1):168-76.
2003: Turner Christopher P; Seli Meltem; Ment Laura; Stewart William; Yan Henglin; Johansson Bjorn; Fredholm Bertil B; Blackburn Michael; Rivkees Scott A
A1 adenosine receptors mediate hypoxia-induced ventriculomegaly.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11718-22.
2003: Schulte Gunnar; Fredholm Bertil B
Signalling from adenosine receptors to mitogen-activated protein kinases.
Cellular signalling 2003;15(9):813-27.
2003: Hammarberg Christian; Schulte Gunnar; Fredholm Bertil B
Evidence for functional adenosine A3 receptors in microglia cells.
Journal of neurochemistry 2003;86(4):1051-4.
2003: Lynge Jan; Schulte Gunnar; Nordsborg Nikolai; Fredholm Bertil B; Hellsten Ylva
Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells.
Biochemical and biophysical research communications 2003;307(1):180-7.
2003: Fredholm Bertil B
Adenosine receptors as targets for drug development.
Drug news & perspectives 2003;16(5):283-9.
2003: Fredholm Bertil B; Assender Jean W; Irenius Eva; Kodama Noriko; Saito Naoaki
Synergistic effects of adenosine A1 and P2Y receptor stimulation on calcium mobilization and PKC translocation in DDT1 MF-2 cells.
Cellular and molecular neurobiology 2003;23(3):379-400.
2003: Adén Ulrika; Halldner Linda; Lagercrantz Hugo; Dalmau Ishar; Ledent Catherine; Fredholm Bertil B
Aggravated brain damage after hypoxic ischemia in immature adenosine A2A knockout mice.
Stroke; a journal of cerebral circulation 2003;34(3):739-44.
2003: Schulte G; Robertson B; Fredholm B B; DeLander G E; Shortland P; Molander C
Distribution of antinociceptive adenosine A1 receptors in the spinal cord dorsal horn, and relationship to primary afferents and neuronal subpopulations.
Neuroscience 2003;121(4):907-16.
2003: Fredholm Bertil B; Cunha Rodrigo A; Svenningsson Per
Pharmacology of adenosine A2A receptors and therapeutic applications.
Current topics in medicinal chemistry 2003;3(4):413-26.
2002: Schulte Gunnar; Fredholm Bertil B
Signaling pathway from the human adenosine A(3) receptor expressed in Chinese hamster ovary cells to the extracellular signal-regulated kinase 1/2.
Molecular pharmacology 2002;62(5):1137-46.
2002: Masino Susan A; Diao Lihong; Illes Peter; Zahniser Nancy R; Larson Gaynor A; Johansson Björn; Fredholm Bertil B; Dunwiddie Thomas V
Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine a(1) receptors.
The Journal of pharmacology and experimental therapeutics 2002;303(1):356-63.
2002: Giménez-Llort Lydia; Fernández-Teruel Alberto; Escorihuela Rosa Maria; Fredholm Bertil B; Tobeña Adolf; Pekny Milos; Johansson Björn
Mice lacking the adenosine A1 receptor are anxious and aggressive, but are normal learners with reduced muscle strength and survival rate.
The European journal of neuroscience 2002;16(3):547-50.
2002: Lindskog Maria; Svenningsson Per; Pozzi Laura; Kim Yong; Fienberg Allen A; Bibb James A; Fredholm Bertil B; Nairn Angus C; Greengard Paul; Fisone Gilberto
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine.
Nature 2002;418(6899):774-8.
2002: Adén Ulrika; Dahlberg Viktoria; Fredholm Bertil B; Lai Li-Ju; Chen Zhengguan; Bjelke Börje
MRI evaluation and functional assessment of brain injury after hypoxic ischemia in neonatal mice.
Stroke; a journal of cerebral circulation 2002;33(5):1405-10.
2002: Fredholm Bertil B; Fleming William W; Vanhoutte Paul M; Godfraind Théophile
The role of pharmacology in drug discovery.
Nature reviews. Drug discovery 2002;1(3):237-8.
2002: Fredholm Bertil B
[The passion concerning behavior of human beings. The intensive sociology debate and some lessons learned from it]
Läkartidningen 2002;99(14):1604-8.
2002: Arslan Giulia; Kull Björn; Fredholm Bertil B
Anoxia redistributes adenosine A(2A) receptors in PC12 cells and increases receptor-mediated formation of cAMP.
Naunyn-Schmiedeberg's archives of pharmacology 2002;365(2):150-7.
2002: Schulte Gunnar; Fredholm Bertil B
Diverse inhibitors of intracellular signalling act as adenosine receptor antagonists.
Cellular signalling 2002;14(2):109-13.
2002: Wu W-P; Hao J-X; Halldner-Henriksson L; Xu X-J; Jacobson M A; Wiesenfeld-Hallin Z; Fredholm B B
Decreased inflammatory pain due to reduced carrageenan-induced inflammation in mice lacking adenosine A3 receptors.
Neuroscience 2002;114(3):523-7.
2002: Lopes L V; Cunha R A; Kull B; Fredholm B B; Ribeiro J A
Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition.
Neuroscience 2002;112(2):319-29.
2001: Brown R; Ollerstam A; Johansson B; Skøtt O; Gebre-Medhin S; Fredholm B; Persson A E
Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(5):R1362-7.
2001: Adén U; Leverin A L; Hagberg H; Fredholm B B
Adenosine A(1) receptor agonism in the immature rat brain and heart.
European journal of pharmacology 2001;426(3):185-92.
2001: Johansson B; Halldner L; Dunwiddie T V; Masino S A; Poelchen W; Giménez-Llort L; Escorihuela R M; Fernández-Teruel A; Wiesenfeld-Hallin Z; Xu X J; Hårdemark A; Betsholtz C; Herlenius E; Fredholm B B
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(16):9407-12.
2001: Basheer R; Halldner L; Alanko L; McCarley R W; Fredholm B B; Porkka-Heiskanen T
Opposite changes in adenosine A1 and A2A receptor mRNA in the rat following sleep deprivation.
Neuroreport 2001;12(8):1577-80.
2001: Fredholm B B; Irenius E; Kull B; Schulte G
Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells.
Biochemical pharmacology 2001;61(4):443-8.
2000: Fredholm B B; Arslan G; Halldner L; Kull B; Schulte G; Wasserman W
Structure and function of adenosine receptors and their genes.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(4-5):364-74.
2000: Halldner L; Lozza G; Lindström K; Fredholm B B
Lack of tolerance to motor stimulant effects of a selective adenosine A(2A) receptor antagonist.
European journal of pharmacology 2000;406(3):345-54.
2000: Arslan G; Fredholm B B
Stimulatory and inhibitory effects of adenosine A(2A) receptors on nerve growth factor-induced phosphorylation of extracellular regulated kinases 1/2 in PC12 cells.
Neuroscience letters 2000;292(3):183-6.
2000: Kull B; Svenningsson P; Fredholm B B
Adenosine A(2A) receptors are colocalized with and activate g(olf) in rat striatum.
Molecular pharmacology 2000;58(4):771-7.
2000: Kull B; Svenningsson P; Hall H; Fredholm B B
GTP differentially affects antagonist radioligand binding to adenosine A(1) and A(2A) receptors in human brain.
Neuropharmacology 2000;39(12):2374-80.
2000: Schulte G; Fredholm B B
Human adenosine A(1), A(2A), A(2B), and A(3) receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2.
Molecular pharmacology 2000;58(3):477-82.
2000: Zahniser N R; Simosky J K; Mayfield R D; Negri C A; Hanania T; Larson G A; Kelly M A; Grandy D K; Rubinstein M; Low M J; Fredholm B B
Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(16):5949-57.
2000: Adén U; Herlenius E; Tang L Q; Fredholm B B
Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain.
Pediatric research 2000;48(2):177-83.
2000: Broad R M; Fallahi N; Fredholm B B
Nitric oxide interacts with oxygen free radicals to evoke the release of adenosine and adenine nucleotides from rat hippocampal slices.
Journal of the autonomic nervous system 2000;81(1-3):82-6.
2000: Svenningsson P; Fienberg A A; Allen P B; Moine C L; Lindskog M; Fisone G; Greengard P; Fredholm B B
Dopamine D(1) receptor-induced gene transcription is modulated by DARPP-32.
Journal of neurochemistry 2000;75(1):248-57.
2000: Svenningsson P; Lindskog M; Ledent C; Parmentier M; Greengard P; Fredholm B B; Fisone G
Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(4):1856-60.
2000: Arslan G; Filipeanu C M; Irenius E; Kull B; Clementi E; Allgaier C; Erlinge D; Fredholm B B
P2Y receptors contribute to ATP-induced increases in intracellular calcium in differentiated but not undifferentiated PC12 cells.
Neuropharmacology 2000;39(3):482-96.
2000: Kuzmin A; Johansson B; Fredholm B B; Ogren S O
Genetic evidence that cocaine and caffeine stimulate locomotion in mice via different mechanisms.
Life sciences 2000;66(8):PL113-8.
2000: Svenningsson P; Fredholm B B; Bloch B; Le Moine C
Co-stimulation of D(1)/D(5) and D(2) dopamine receptors leads to an increase in c-fos messenger RNA in cholinergic interneurons and a redistribution of c-fos messenger RNA in striatal projection neurons.
Neuroscience 2000;98(4):749-57.
1999: Svenningsson P; Le Moine C; Fisone G; Fredholm B B
Distribution, biochemistry and function of striatal adenosine A2A receptors.
Progress in neurobiology 1999;59(4):355-96.
1999: Fredholm B B; Lindström K
Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A1 and A(2A) receptors.
European journal of pharmacology 1999;380(2-3):197-202.
1999: Kull B; Ferré S; Arslan G; Svenningsson P; Fuxe K; Owman C; Fredholm B B
Reciprocal interactions between adenosine A2A and dopamine D2 receptors in Chinese hamster ovary cells co-transfected with the two receptors.
Biochemical pharmacology 1999;58(6):1035-45.
1999: Lindskog M; Svenningsson P; Fredholm B; Greengard P; Fisone G
Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons.
The European journal of neuroscience 1999;11(6):2182-6.
1999: Svenningsson P; Nomikos G G; Fredholm B B
The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(10):4011-22.
1999: Svenningsson P; Fourreau L; Bloch B; Fredholm B B; Gonon F; Le Moine C
Opposite tonic modulation of dopamine and adenosine on c-fos gene expression in striatopallidal neurons.
Neuroscience 1999;89(3):827-37.
1999: Arslan G; Kull B; Fredholm B B
Signaling via A2A adenosine receptor in four PC12 cell clones.
Naunyn-Schmiedeberg's archives of pharmacology 1999;359(1):28-32.
1999: Ongini E; Dionisotti S; Gessi S; Irenius E; Fredholm B B
Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors.
Naunyn-Schmiedeberg's archives of pharmacology 1999;359(1):7-10.
1999: Kull B; Arslan G; Nilsson C; Owman C; Lorenzen A; Schwabe U; Fredholm B B
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.
Biochemical pharmacology 1999;57(1):65-75.
1999: Arslan G; Fredholm B B
Adenosine and P2 receptors in PC12 cells. Genotypic, phenotypic and individual differences.
Progress in brain research 1999;120():301-10.
1999: Lindskog M; Svenningsson P; Fredholm B B; Greengard P; Fisone G
Activation of dopamine D2 receptors decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neurons via different mechanisms.
Neuroscience 1999;88(4):1005-8.
1998: Svenningsson P; Le Moine C; Aubert I; Burbaud P; Fredholm B B; Bloch B
Cellular distribution of adenosine A2A receptor mRNA in the primate striatum.
The Journal of comparative neurology 1998;399(2):229-40.
1998: Svenningsson P; Lindskog M; Rognoni F; Fredholm B B; Greengard P; Fisone G
Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons.
Neuroscience 1998;84(1):223-8.
1998: Fredholm B B; Johansson B; Lindström K; Wahlström G
Age-dependent changes in adenosine receptors are not modified by life-long intermittent alcohol administration.
Brain research 1998;791(1-2):177-85.
1998: Fredholm B B; Lindström K; Dionisotti S; Ongini E
[3H]SCH 58261, a selective adenosine A2A receptor antagonist, is a useful ligand in autoradiographic studies.
Journal of neurochemistry 1998;70(3):1210-6.
1998: Fredholm B B
[Thoughts at the start of a new year. What happens to time?]
Läkartidningen 1998;95(6):534-5.
1998: Ferré S; Torvinen M; Antoniou K; Irenius E; Civelli O; Arenas E; Fredholm B B; Fuxe K
Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells.
The Journal of biological chemistry 1998;273(8):4718-24.
1998: Klotz K N; Hessling J; Hegler J; Owman C; Kull B; Fredholm B B; Lohse M J
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.
Naunyn-Schmiedeberg's archives of pharmacology 1998;357(1):1-9.
1998: Svenningsson P; Nergårdh R; Fredholm B B
Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat.
Neuropharmacology 1998;37(3):331-7.
1997: Jin S; Fredholm B B
Glucose deprivation increases basal and electrically evoked transmitter release from rat striatal slices. Role of NMDA and adenosine A1 receptors.
European journal of pharmacology 1997;340(2-3):169-75.
1997: Fredholm B
[Our genetic differences confirm the idea on equal value of all human beings]
Läkartidningen 1997;94(49):4650-1.
1997: Svenningsson P; Hall H; Sedvall G; Fredholm B B
Distribution of adenosine receptors in the postmortem human brain: an extended autoradiographic study.
Synapse (New York, N.Y.) 1997;27(4):322-35.
1997: Chergui K; Svenningsson P; Nomikos G G; Gonon F; Fredholm B B; Svennson T H
Increased expression of NGFI-A mRNA in the rat striatum following burst stimulation of the medial forebrain bundle.
The European journal of neuroscience 1997;9(11):2370-82.
1997: Svenningsson P; Georgieva J; Kontny E; Heilig M; Fredholm B B
Involvement of a c-fos-dependent mechanism in caffeine-induced expression of the preprotachykinin A and neurotensin/neuromedin N genes in rat striatum.
The European journal of neuroscience 1997;9(10):2135-41.
1997: Le Moine C; Svenningsson P; Fredholm B B; Bloch B
Dopamine-adenosine interactions in the striatum and the globus pallidus: inhibition of striatopallidal neurons through either D2 or A2A receptors enhances D1 receptor-mediated effects on c-fos expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(20):8038-48.
1997: Johansson B; Georgiev V; Fredholm B B
Distribution and postnatal ontogeny of adenosine A2A receptors in rat brain: comparison with dopamine receptors.
Neuroscience 1997;80(4):1187-207.
1997: Svenningsson P; Le Moine C; Kull B; Sunahara R; Bloch B; Fredholm B B
Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas.
Neuroscience 1997;80(4):1171-85.
1997: Arslan G; Kontny E; Fredholm B B
Down-regulation of adenosine A2A receptors upon NGF-induced differentiation of PC12 cells.
Neuropharmacology 1997;36(9):1319-26.
1997: Svenningsson P; Fredholm B B
Caffeine mimics the effect of a dopamine D2/3 receptor agonist on the expression of immediate early genes in globus pallidus.
Neuropharmacology 1997;36(9):1309-17.
1997: Jin S; Fredholm B B
Electrically-evoked dopamine and acetylcholine release from rat striatal slices perfused without magnesium: regulation by glutamate acting on NMDA receptors.
British journal of pharmacology 1997;121(7):1269-76.
1997: Svenningsson P; Nomikos G G; Ongini E; Fredholm B B
Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens.
Neuroscience 1997;79(3):753-64.
1997: Johansson B; Georgiev V; Lindström K; Fredholm B B
A1 and A2A adenosine receptors and A1 mRNA in mouse brain: effect of long-term caffeine treatment.
Brain research 1997;762(1-2):153-64.
1997: Assender J W; Irenius E; Fredholm B B
5-Hydroxytryptamine, angiotensin and bradykinin transiently increase intracellular calcium concentrations and PKC-alpha activity, but do not induce mitogenesis in human vascular smooth muscle cells.
Acta physiologica Scandinavica 1997;160(3):207-17.
1997: Jin S; Fredholm B B
Adenosine A1 receptors mediate hypoxia-induced inhibition of electrically evoked transmitter release from rat striatal slices.
European journal of pharmacology 1997;329(2-3):107-13.
1997: Dionisotti S; Ongini E; Zocchi C; Kull B; Arslan G; Fredholm B B
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.
British journal of pharmacology 1997;121(3):353-60.
1997: Fredholm B B
[New series: action mechanisms of drugs]
Läkartidningen 1997;94(19):1787-8.
1997: Fredholm B B; Abbracchio M P; Burnstock G; Dubyak G R; Harden T K; Jacobson K A; Schwabe U; Williams M
Towards a revised nomenclature for P1 and P2 receptors.
Trends in pharmacological sciences 1997;18(3):79-82.
1997: Fredholm B B
Purines and neutrophil leukocytes.
General pharmacology 1997;28(3):345-50.
1997: Kontny E; Ciruela F; Svenningsson P; Ibáñez C F; Fredholm B B
On the role of the low-affinity neurotrophin receptor p75LNTR in nerve growth factor induction of differentiation and AP 1 binding activity in PC12 cells.
Journal of molecular neuroscience : MN 1997;8(1):29-44.
1997: Svenningsson P; Fredholm B B
Glucocorticoids regulate the expression of adenosine A1 but not A(2A) receptors in rat brain.
The Journal of pharmacology and experimental therapeutics 1997;280(2):1094-101.
1997: Jin S; Fredholm B B
Adenosine A2A receptor stimulation increases release of acetylcholine from rat hippocampus but not striatum, and does not affect catecholamine release.
Naunyn-Schmiedeberg's archives of pharmacology 1997;355(1):48-56.
1997: Fredholm B B
Adenosine and neuroprotection.
International review of neurobiology 1997;40():259-80.
1996: Johansson B; Georgiev V; Kuosmanen T; Fredholm B B
Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding.
The European journal of neuroscience 1996;8(12):2447-58.
1996: Dasgupta S; Ferré S; Kull B; Hedlund P B; Finnman U B; Ahlberg S; Arenas E; Fredholm B B; Fuxe K
Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells.
European journal of pharmacology 1996;316(2-3):325-31.
1996: Zhang Y; Raud J; Hedqvist P; Fredholm B B
Propentofylline inhibits polymorphonuclear leukocyte recruitment in vivo by a mechanism involving adenosine A2A receptors.
European journal of pharmacology 1996;313(3):237-42.
1996: Lindström K; Ongini E; Fredholm B B
The selective adenosine A2A receptor antagonist SCH 58261 discriminates between two different binding sites for [3H]-CGS 21680 in the rat brain.
Naunyn-Schmiedeberg's archives of pharmacology 1996;354(4):539-41.
1996: Fredholm B B; Wallman-Johansson A
Effects of ethanol and acetate on adenosine production in rat hippocampal slices.
Pharmacology & toxicology 1996;79(3):120-3.
1996: Fredholm B B; Zhang Y; van der Ploeg I
Adenosine A2A receptors mediate the inhibitory effect of adenosine on formyl-Met-Leu-Phe-stimulated respiratory burst in neutrophil leucocytes.
Naunyn-Schmiedeberg's archives of pharmacology 1996;354(3):262-7.
1996: Assender J W; Irenius E; Fredholm B B
Endothelin-1 causes a prolonged protein kinase C activation and acts as a co-mitogen in vascular smooth muscle cells.
Acta physiologica Scandinavica 1996;157(4):451-60.
1996: Zhang Y; Palmblad J; Fredholm B B
Biphasic effect of ATP on neutrophil functions mediated by P2U and adenosine A2A receptors.
Biochemical pharmacology 1996;51(7):957-65.
1996: Broad R M; Fredholm B B
A1, but not A2A, adenosine receptors modulate electrically stimulated [14C]acetylcholine release from rat cortex.
The Journal of pharmacology and experimental therapeutics 1996;277(1):193-7.
1996: van der Ploeg I; Ahlberg S; Parkinson F E; Olsson R A; Fredholm B B
Functional characterization of adenosine A2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists.
Naunyn-Schmiedeberg's archives of pharmacology 1996;353(3):250-60.
1996: Svenningsson P; Johansson B; Fredholm B B
Caffeine-induced expression of c-fos mRNA and NGFI-A mRNA in caudate putamen and in nucleus accumbens are differentially affected by the N-methyl-D-aspartate receptor antagonist MK-801.
Brain research. Molecular brain research 1996;35(1-2):183-9.
1996: Fredholm B B; Adén U; Lindström K; Bona E; Hagberg H
Caffeine and ischemia--effects on immediate early genes and adenosine receptors.
Advances in neurology 1996;71():469-74.
1995: Svenningsson P; Nomikos G G; Fredholm B B
Biphasic changes in locomotor behavior and in expression of mRNA for NGFI-A and NGFI-B in rat striatum following acute caffeine administration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(11):7612-24.
1995: Bona E; Adén U; Fredholm B B; Hagberg H
The effect of long term caffeine treatment on hypoxic-ischemic brain damage in the neonate.
Pediatric research 1995;38(3):312-8.
1995: Assender J W; Irenius E; Fredholm B B
Protein kinase C isoform expression and ATP response change with smooth muscle cell differentiation.
Biochemical Society transactions 1995;23(3):453S.
1995: Svenningsson P; Ström A; Johansson B; Fredholm B B
Increased expression of c-jun, junB, AP-1, and preproenkephalin mRNA in rat striatum following a single injection of caffeine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(5 Pt 1):3583-93.
1995: Svenningsson P; Johansson B; Fredholm B B
Effect of different xanthines and phosphodiesterase inhibitors on c-fos expression in rat striatum.
Acta physiologica Scandinavica 1995;154(1):17-24.
1995: Fredholm B B; Heldin C H
[Growth factors--clarification of their mechanism]
Läkartidningen 1995;92(14):1459-62, 1467.
1995: Fredholm B B; Heldin C H
[A new series: growth factors]
Läkartidningen 1995;92(14):1454, 1457.
1995: Lloyd H G; Fredholm B B
Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices.
Neurochemistry international 1995;26(4):387-95.
1995: Fredholm B B
Purinoceptors in the nervous system.
Pharmacology & toxicology 1995;76(4):228-39.
1995: Johansson B; Fredholm B B
Further characterization of the binding of the adenosine receptor agonist [3H]CGS 21680 to rat brain using autoradiography.
Neuropharmacology 1995;34(4):393-403.
1995: Gerwins P; Fredholm B B
Activation of phospholipase C and phospholipase D by stimulation of adenosine A1, bradykinin or P2U receptors does not correlate well with protein kinase C activation.
Naunyn-Schmiedeberg's archives of pharmacology 1995;351(2):194-201.
1995: Gerwins P; Fredholm B B
Activation of adenosine A1 and bradykinin receptors increases protein kinase C and phospholipase D activity in smooth muscle cells.
Naunyn-Schmiedeberg's archives of pharmacology 1995;351(2):186-93.
1995: Fredholm B B
Astra Award Lecture. Adenosine, adenosine receptors and the actions of caffeine.
Pharmacology & toxicology 1995;76(2):93-101.
1994: Snaprud P; Gerwins P; Caron M G; Libert F; Persson H; Fredholm B B; Fuxe K
A2a/D2 receptor interactions are not observed in COS-7 cells transiently transfected with dopamine D2 and adenosine A2a receptor cDNA.
Biochemical pharmacology 1994;48(11):2043-7.
1994: Zhang Y; Fredholm B B
Propentofylline enhancement of the actions of adenosine on neutrophil leukocytes.
Biochemical pharmacology 1994;48(11):2025-32.
1994: Adén U; Bona E; Hagberg H; Fredholm B B
Changes in c-fos mRNA in the neonatal rat brain following hypoxic ischemia.
Neuroscience letters 1994;180(2):91-5.
1994: Jin S; Fredholm B B
Role of NMDA, AMPA and kainate receptors in mediating glutamate- and 4-AP-induced dopamine and acetylcholine release from rat striatal slices.
Neuropharmacology 1994;33(9):1039-48.
1994: Dunér-Engström M; Fredholm B B
Carbachol-induced phosphatidylcholine hydrolysis and choline efflux in rat submandibular gland involves phospholipase D activation and is modulated by protein kinase C and calcium.
Acta physiologica Scandinavica 1994;151(4):515-25.
1994: Fredholm B B; Altiok N
Adenosine A2B receptor signalling is altered by stimulation of bradykinin or interleukin receptors in astroglioma cells.
Neurochemistry international 1994;25(1):99-102.
1994: Adén U; Lindström K; Bona E; Hagberg H; Fredholm B B
Changes in adenosine receptors in the neonatal rat brain following hypoxic ischemia.
Brain research. Molecular brain research 1994;23(4):354-8.
1994: Fredholm B B; Abbracchio M P; Burnstock G; Daly J W; Harden T K; Jacobson K A; Leff P; Williams M
Nomenclature and classification of purinoceptors.
Pharmacological reviews 1994;46(2):143-56.
1994: Johansson B; Lindström K; Fredholm B B
Differences in the regional and cellular localization of c-fos messenger RNA induced by amphetamine, cocaine and caffeine in the rat.
Neuroscience 1994;59(4):837-49.
1994: Fredholm B B
[The mechanism of acetylsalicylic acid becomes clearer]
Läkartidningen 1994;91(12):1177, 1180-1.
1994: Assender J W; Kontny E; Fredholm B B
Expression of protein kinase C isoforms in smooth muscle cells in various states of differentiation.
FEBS letters 1994;342(1):76-80.
1994: Fredholm B B; Lindström K; Wallman-Johansson A
Propentofylline and other adenosine transport inhibitors increase the efflux of adenosine following electrical or metabolic stimulation of rat hippocampal slices.
Journal of neurochemistry 1994;62(2):563-73.
1994: Wallman-Johansson A; Fredholm B B
Release of adenosine and other purines from hippocampal slices stimulated electrically or by hypoxia/hypoglycemia. Effect of chlormethiazole.
Life sciences 1994;55(9):721-8.
1993: Johansson B; Herrera-Marschitz M; Svenningson P; Fredholm B B
Caffeine-induced expression of the proto-oncogene c-fos in rat striatum is increased after dopamine denervation.
Acta physiologica Scandinavica 1993;149(4):527-9.
1993: Jin S; Johansson B; Fredholm B B
Effects of adenosine A1 and A2 receptor activation on electrically evoked dopamine and acetylcholine release from rat striatal slices.
The Journal of pharmacology and experimental therapeutics 1993;267(2):801-8.
1993: Johansson B; Georgiev V; Parkinson F E; Fredholm B B
The binding of the adenosine A2 receptor selective agonist [3H]CGS 21680 to rat cortex differs from its binding to rat striatum.
European journal of pharmacology 1993;247(2):103-10.
1993: Dunér-Engström M; Fredholm B B
Breakdown of membrane choline-phospholipids induced by endogenous and exogenous muscarinic agonist is potentiated by VIP in rat submandibular gland.
Acta physiologica Scandinavica 1993;149(1):41-9.
1993: Lloyd H G; Lindström K; Fredholm B B
Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion.
Neurochemistry international 1993;23(2):173-85.
1993: Georgiev V; Johansson B; Fredholm B B
Long-term caffeine treatment leads to a decreased susceptibility to NMDA-induced clonic seizures in mice without changes in adenosine A1 receptor number.
Brain research 1993;612(1-2):271-7.
1993: Altiok N; Fredholm B B
Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase.
Cellular signalling 1993;5(3):279-88.
1993: Johansson B; Ahlberg S; van der Ploeg I; Brené S; Lindefors N; Persson H; Fredholm B B
Effect of long term caffeine treatment on A1 and A2 adenosine receptor binding and on mRNA levels in rat brain.
Naunyn-Schmiedeberg's archives of pharmacology 1993;347(4):407-14.
1993: Fredholm B B
Presynaptic regulation of hippocampal acetylcholine release is unaffected by calcium channel blockers and intracellular calcium chelation.
Acta physiologica Scandinavica 1993;147(4):461-3.
1993: Fredholm B B; Hu P S
Effect of an intracellular calcium chelator on the regulation of electrically evoked [3H]-noradrenaline release from rat hippocampal slices.
British journal of pharmacology 1993;108(1):126-31.
1993: Fredholm B B; Gerwins P; Johansson B; Parkinson F E; van der Ploeg I
Signalling via G-protein coupled receptors--using adenosine receptors as an example.
Drug design and discovery 1993;9(3-4):189-97.
1992: Johansson B; Parkinson F E; Fredholm B B
Effects of mono- and divalent ions on the binding of the adenosine analogue CGS 21680 to adenosine A2 receptors in rat striatum.
Biochemical pharmacology 1992;44(12):2365-70.
1992: Meana J J; Johansson B; Herrera-Marschitz M; O'Connor W T; Goiny M; Parkinson F E; Fredholm B B; Ungerstedt U
Effect of the neurotoxin AF64A on intrinsic and extrinsic neuronal systems of rat neostriatum measured by in vivo microdialysis.
Brain research 1992;596(1-2):65-72.
1992: Dunér-Engström M; Larsson O; Fredholm B B; Lundblad L; Fahrenkrug J; Lundberg J M
Effects of acute and long-term atropine treatment on levels, release and response to VIP and PHI in the submandibular gland of cat and rat.
Acta physiologica Scandinavica 1992;146(3):357-67.
1992: Kontny E; Kvanta A; Fredholm B B
Activation of protein kinase C and elevation of cAMP interact synergistically to raise c-Fos and AP-1 activity in Jurkat cells.
European journal of pharmacology 1992;227(3):333-8.
1992: Balmforth A J; Parkinson F E; Altiok N; Fredholm B B
Identification of a B2-bradykinin receptor linked to phospholipase C and inhibition of dopamine stimulated cyclic AMP accumulation in the human astrocytoma cell line D384.
Naunyn-Schmiedeberg's archives of pharmacology 1992;346(3):303-10.
1992: Altiok N; Fredholm B B
Bradykinin inhibition of cyclic AMP accumulation in D384 astrocytoma cells. Evidence against a role of cyclic GMP.
Neurochemistry international 1992;21(2):209-13.
1992: Gerwins P; Fredholm B B
Stimulation of adenosine A1 receptors and bradykinin receptors, which act via different G proteins, synergistically raises inositol 1,4,5-trisphosphate and intracellular free calcium in DDT1 MF-2 smooth muscle cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7330-4.
1992: Gerwins P; Fredholm B B
ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line.
The Journal of biological chemistry 1992;267(23):16081-7.
1992: Kvanta A; Kontny E; Jondal M; Okret S; Fredholm B B
Mitogen stimulation of T-cells increases c-Fos and c-Jun protein levels, AP-1 binding and AP-1 transcriptional activity.
Cellular signalling 1992;4(3):275-86.
1992: Hu P S; Jin S; Fredholm B B
Glycine and GABA potentiate 4-aminopyridine and/or N-methyl-D-aspartate induced [3H]-noradrenaline release from rat hippocampal slices.
Acta physiologica Scandinavica 1992;145(1):77-8.
1992: van der Ploeg I; Parkinson F E; Fredholm B B
Effect of pertussis toxin on radioligand binding to rat brain adenosine A1 receptors.
Journal of neurochemistry 1992;58(4):1221-9.
1992: Parkinson F E; Fredholm B B
Magnesium-dependent enhancement of endogenous agonist binding to A1 adenosine receptors: a complicating factor in quantitative autoradiography.
Journal of neurochemistry 1992;58(3):941-50.
1992: Altiok N; Balmforth A J; Fredholm B B
Adenosine receptor-induced cAMP changes in D384 astrocytoma cells and the effect of bradykinin thereon.
Acta physiologica Scandinavica 1992;144(1):55-63.
1992: Fredholm B B; Fastbom J; Kvanta A; Gerwins P; Parkinson F
Further evidence that propentofylline (HWA 285) influences both adenosine receptors and adenosine transport.
Fundamental & clinical pharmacology 1992;6(3):99-111.
1991: Hu P S; Benishin C; Fredholm B B
Comparison of the effects of four dendrotoxin peptides, 4-aminopyridine and tetraethylammonium on the electrically evoked [3H]noradrenaline release from rat hippocampus.
European journal of pharmacology 1991;209(1-2):87-93.
1991: van der Ploeg I; Altiok N; Kvanta A; Nordstedt C; Fredholm B B
Role of a pertussis toxin sensitive G-protein in mediating the effects of phorbol esters on receptor activated cyclic AMP accumulation in Jurkat cells.
Naunyn-Schmiedeberg's archives of pharmacology 1991;344(5):611-7.
1991: Parkinson F E; Fredholm B B
Effects of propentofylline on adenosine A1 and A2 receptors and nitrobenzylthioinosine-sensitive nucleoside transporters: quantitative autoradiographic analysis.
European journal of pharmacology 1991;202(3):361-6.
1991: Hu P S; Jin S; Fredholm B B
4-Aminopyridine-induced noradrenaline release from the rat hippocampus depends on the activation of glutamate receptors of the non-NMDA type.
Acta physiologica Scandinavica 1991;143(1):139-40.
1991: Gerwins P; Fredholm B B
Glucocorticoid receptor activation leads to up-regulation of adenosine A1 receptors and down-regulation of adenosine A2 responses in DDT1 MF-2 smooth muscle cells.
Molecular pharmacology 1991;40(2):149-55.
1991: Kvanta A; Jondal M; Fredholm B B
CD3-dependent increase in cyclic AMP in human T-cells following stimulation of the CD2 receptor.
Biochimica et biophysica acta 1991;1093(2-3):178-83.
1991: Kvanta A; Jondal M; Fredholm B B
Translocation of the alpha- and beta-isoforms of protein kinase C following activation of human T-lymphocytes.
FEBS letters 1991;283(2):321-4.
1991: Van der Ploeg I; Fredholm B B; Carlquist M; Bertorello A; Aperia A; Celsi G
Localization of several G-protein subunits to the apical and basolateral membranes of cortical tubular cells from the rat kidney.
Acta physiologica Scandinavica 1991;142(1):83-90.
1991: Stiller C O; Fastbom J; Fredholm B B; Brodin E
The adenosine analogue R-PIA interacts with substance P binding in rat brain and spinal cord.
Acta physiologica Scandinavica 1991;141(4):573-4.
1991: Hu P S; Fredholm B B
4-Aminopyridine-induced increase in basal and stimulation-evoked [3H]-NA release in slices from rat hippocampus: Ca2+ sensitivity and presynaptic control.
British journal of pharmacology 1991;102(3):764-8.
1991: van der Ploeg I; Cintra A; Altiok N; Askelöf P; Fuxe K; Fredholm B B
Limited distribution of pertussis toxin in rat brain after injection into the lateral cerebral ventricles.
Neuroscience 1991;44(1):205-14.
1990: Larsson O; Detsch T; Fredholm B B
VIP and forskolin enhance carbachol-induced K+ efflux from rat salivary gland fragments by a Ca2(+)-sensitive mechanism.
The American journal of physiology 1990;259(6 Pt 1):C904-10.
1990: Kvanta A; Gerwins P; van der Ploeg I; Nordstedt C; Jondal M; Fredholm B B
Stimulation of the T-cell receptors CD3 and CD2 with OKT3 and OKT11 antibodies activates a common pertussis toxin-insensitive G-protein.
European journal of pharmacology 1990;189(6):363-72.
1990: Gerwins P; Nordstedt C; Fredholm B B
Characterization of adenosine A1 receptors in intact DDT1 MF-2 smooth muscle cells.
Molecular pharmacology 1990;38(5):660-6.
1990: Fredholm B B
Adenosine A1-receptor-mediated inhibition of evoked acetylcholine release in the rat hippocampus does not depend on protein kinase C.
Acta physiologica Scandinavica 1990;140(2):245-55.
1990: Andiné P; Rudolphi K A; Fredholm B B; Hagberg H
Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia.
British journal of pharmacology 1990;100(4):814-8.
1990: Parkinson F E; Fredholm B B
Autoradiographic evidence for G-protein coupled A2-receptors in rat neostriatum using [3H]-CGS 21680 as a ligand.
Naunyn-Schmiedeberg's archives of pharmacology 1990;342(1):85-9.
1990: Fredholm B; Abbott A
New targets for drug action: is high selectivity always beneficial?
Trends in pharmacological sciences 1990;11(5):175-8.
1990: Fredholm B B
Differential sensitivity to blockade by 4-aminopyridine of presynaptic receptors regulating [3H]acetylcholine release from rat hippocampus.
Journal of neurochemistry 1990;54(4):1386-90.
1990: Fastbom J; Post C; Fredholm B B
Antinociceptive effects and spinal distribution of two adenosine receptor agonists after intrathecal administration.
Pharmacology & toxicology 1990;66(1):69-72.
1990: Kvanta A; Nordstedt C; Fredholm B; Gullberg M; Jondal M
Evidence that protein kinase C activation is essential for killing by IL-2-activated lymphocytes.
Scandinavian journal of immunology 1990;31(1):103-8.
1990: Fastbom J; Fredholm B B
Effects of long-term theophylline treatment on adenosine A1-receptors in rat brain: autoradiographic evidence for increased receptor number and altered coupling to G-proteins.
Brain research 1990;507(2):195-9.
1990: Fastbom J; Fredholm B B
Regional differences in the effect of guanine nucleotides on agonist and antagonist binding to adenosine A1-receptors in rat brain, as revealed by autoradiography.
Neuroscience 1990;34(3):759-69.
1990: Kvanta A; Gerwins P; Jondal M; Fredholm B B
Stimulation of T-cells with OKT3 antibodies increases forskolin binding and cyclic AMP accumulation.
Cellular signalling 1990;2(5):461-70.
1990: Fredholm B B; Dunér-Engström M; Fastbom J; Hu P S; van der Ploeg I
Role of G proteins, cyclic AMP, and ion channels in the inhibition of transmitter release by adenosine.
Annals of the New York Academy of Sciences 1990;604():276-88.
1989: Kvanta A; Nordstedt C; Jondal M; Fredholm B B
Activation of protein kinase C via the T-cell receptor complex potentiates cyclic AMP responses in T-cells.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(6 Pt 2):715-7.
1989: Fredholm B B; Dunér-Engström M
Propentofylline and a hydroxy metabolite augment A2-receptor mediated cyclic AMP accumulation and attenuate A1-receptor mediated inhibition of acetylcholine release in the rat hippocampus.
Pharmacology & toxicology 1989;65(5):347-51.
1989: Runold M; Lagercrantz H; Prabhakar N R; Fredholm B B
Role of adenosine in hypoxic ventilatory depression.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;67(2):541-6.
1989: Fredholm B B; Proctor W; Van der Ploeg I; Dunwiddie T V
In vivo pertussis toxin treatment attenuates some, but not all, adenosine A1 effects in slices of the rat hippocampus.
European journal of pharmacology 1989;172(3):249-62.
1989: Hu P S; Fredholm B B
Alpha 2-adrenoceptor agonist-mediated inhibition of [3H]noradrenaline release from rat hippocampus is reduced by 4-aminopyridine, but that caused by an adenosine analogue or omega-conotoxin is not.
Acta physiologica Scandinavica 1989;136(3):347-53.
1989: Kvanta A; Nordstedt C; van der Ploeg I; Jondal M; Fredholm B B
CD3/T-cell receptor coupling to a pertussis and cholera toxin-insensitive G-protein.
FEBS letters 1989;250(2):536-40.
1989: Larsson O; Fredholm B B
Carbachol stimulation of inositol phosphate accumulation in rat submandibular gland fragments is not modified by VIP.
Acta physiologica Scandinavica 1989;135(3):263-9.
1989: Nordstedt C; Kvanta A; Van der Ploeg I; Fredholm B B
Dual effects of protein kinase-C on receptor-stimulated cAMP accumulation in a human T-cell leukemia line.
European journal of pharmacology 1989;172(1):51-60.
1988: Nordstedt C; Kvanta A; Fredholm B B
Agonist but not phorbol ester induced desensitization of human lymphocyte prostaglandin receptor is dependent on tubulin polymerization.
Biochemical and biophysical research communications 1988;157(3):1046-50.
1988: Ng J; Fredholm B B; Jondal M; Andersson T
Regulation of receptor-mediated calcium influx across the plasma membrane in a human leukemic T-cell line: evidence of its dependence on an initial calcium mobilization from intracellular stores.
Biochimica et biophysica acta 1988;971(2):207-14.
1988: Dunér-Engström M; Fredholm B B
Evidence that prejunctional adenosine receptors regulating acetylcholine release from rat hippocampal slices are linked to an N-ethylmaleimide-sensitive G-protein, but not to adenylate cyclase or dihydropyridine-sensitive Ca2+-channels.
Acta physiologica Scandinavica 1988;134(1):119-26.
1988: Chow S C; NG J; Nordstedt C; Fredholm B B; Jondal M
Phosphoinositide breakdown and evidence for protein kinase C involvement during human NK killing.
Cellular immunology 1988;114(1):96-103.
1988: Fredholm B B; Lindgren E
Protein kinase C activation increases noradrenaline release from the rat hippocampus and modifies the inhibitory effect of alpha 2-adrenoceptor and adenosine A1-receptor agonists.
Naunyn-Schmiedeberg's archives of pharmacology 1988;337(5):477-83.
1988: Lundberg J M; Hemsén A; Rudehill A; Härfstrand A; Larsson O; Sollevi A; Saria A; Hökfelt T; Fuxe K; Fredholm B B
Neuropeptide Y- and alpha-adrenergic receptors in pig spleen: localization, binding characteristics, cyclic AMP effects and functional responses in control and denervated animals.
Neuroscience 1988;24(2):659-72.
1988: Lundberg J M; Hemsén A; Larsson O; Rudehill A; Saria A; Fredholm B B
Neuropeptide Y receptor in pig spleen: binding characteristics, reduction of cyclic AMP formation and calcium antagonist inhibition of vasoconstriction.
European journal of pharmacology 1988;145(1):21-9.
1987: Fredholm B B; Lindgren E; Lindström K; Nordstedt C
Alpha-adrenoceptor stimulation, but not muscarinic stimulation, increases cyclic AMP accumulation in brain slices due to protein kinase C mediated enhancement of adenosine receptor effects.
Acta physiologica Scandinavica 1987;131(4):543-51.
1987: Moss I R; Runold M; Dahlin I; Fredholm B B; Nyberg F; Lagercrantz H
Respiratory and neuroendocrine responses of piglets to hypoxia during postnatal development.
Acta physiologica Scandinavica 1987;131(4):533-41.
1987: Fastbom J; Fredholm B B
Regional differences in the GTP-dependence of adenosine receptor binding in rat brain?
Acta physiologica Scandinavica 1987;131(3):467-9.
1987: Häggblad J; Fredholm B B
Adenosine and neuropeptide Y enhance alpha 1-adrenoceptor-induced accumulation of inositol phosphates and attenuate forskolin-induced accumulation of cyclic AMP in rat vas deferens.
Neuroscience letters 1987;82(2):211-6.
1987: Ng J; Fredholm B B; Jondal M
Studies on the calcium dependence of human NK cell killing.
Biochemical pharmacology 1987;36(22):3943-9.
1987: Hu P S; Lindgren E; Jacobson K A; Fredholm B B
Interaction of dihydropyridine calcium channel agonists and antagonists with adenosine receptors.
Pharmacology & toxicology 1987;61(2):121-5.
1986: Fredholm B B; Hu P S; Lindgren E
The dihydropyridine calcium-channel agonist BayK 8644 inhibits the presynaptic effects of R-phenylisopropyl adenosine in the rat hippocampus.
Acta physiologica Scandinavica 1986;128(4):659-60.

Sign-in to see more