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Robert Fredriksson

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Mathias Rask-Andersen; Robert Fredriksson; Surendar Masuram; Helgi B Schiöth
Solute carriers as drug targets: current use, clinical trials and prospective.
Helgi B Schiöth; Maria G A Hägglund; Sahar Roshanbin; Robert Fredriksson
Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects.
Markus Almén; A Ameur; N Bringeland; G P Chrousos; Robert Fredriksson; Ulf Gyllensten; L A Hedberg; V Ignatovica; J A Jacobsson; S Juhlin; I Kalnina; Janis Klovins; Y Manios; Claude Marcus; George Moschonis; M Rask-Andersen; Helgi B Schiöth
Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

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All Publications

2013: Mathias Rask-Andersen; Robert Fredriksson; Surendar Masuram; Helgi B Schiöth
Solute carriers as drug targets: current use, clinical trials and prospective.
Molecular aspects of medicine 2013;34(2-3):702-10.
2013: Helgi B Schiöth; Maria G A Hägglund; Sahar Roshanbin; Robert Fredriksson
Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects.
Molecular aspects of medicine 2013;34(2-3):571-85.
2013: Markus Almén; A Ameur; N Bringeland; G P Chrousos; Robert Fredriksson; Ulf Gyllensten; L A Hedberg; V Ignatovica; J A Jacobsson; S Juhlin; I Kalnina; Janis Klovins; Y Manios; Claude Marcus; George Moschonis; M Rask-Andersen; Helgi B Schiöth
Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.
International journal of obesity (2005) 2013;37(3):424-31.
2013: Maria G A Hägglund; Sofie V Hellsten; Erik Löfqvist; Victor C O Nilsson; Sahar Roshanbin; Helgi B Schiöth; Olof Stephansson; Aniruddha Todkar; George R. Uhl; Yinan Zhu; Jana Drgonova; Robert Fredriksson
B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain.
PloS one 2013;8(3):e58651.
2012: Michael J Williams; Markus Almén; Robert Fredriksson; Helgi B Schiöth
What model organisms and interactomics can reveal about the genetics of human obesity.
Cellular and molecular life sciences : CMLS 2012;69(22):3819-34.
2012: Åke Västermark; Asa Johansson; Robert Fredriksson; Ulf Gyllensten; Josefin A Jacobsson; Helgi B Schiöth
Polymorphisms in sh2b1 and spns1 loci are associated with triglyceride levels in a healthy population in northern Sweden.
Journal of genetics 2012;91(2):237-40.
2012: G Sundström; B Xu; Tomas A Larsson; Ingrid Lundell; C A Bergqvist; J M Conlon; R J Denver; Robert Fredriksson; J Heldin; Dan Larhammar
Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes.
General and comparative endocrinology 2012;177(3):322-31.
2012: Markus Almén; Christian Benedict; George P Chrousos; Robert Fredriksson; Josefin A Jacobsson; George Moschonis; Helgi B Schiöth
Genome wide analysis reveals association of a FTO gene variant with epigenetic changes.
Genomics 2012;99(3):132-7.
2012: Åke Västermark; José Miguel Cerdá-Reverter; Robert Fredriksson; Michael E Houle; Arunkumar Krishnan; Helgi B Schiöth
Identification of distant Agouti-like sequences and re-evaluation of the evolutionary history of the Agouti-related peptide (AgRP).
PloS one 2012;7(7):e40982.
2012: Mathias Rask-Andersen; George P Chrousos; Anna E Ek; Robert Fredriksson; Josefin A Jacobsson; Yannis Manios; Claude Marcus; George Moschonis; Helgi B Schiöth
The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children.
BMC medical genetics 2012;13():36.
2012: Pawel K Olszewski; Birgit Rathkolb; Ulf Risérus; Jan Rozman; Helgi B Schiöth; Siv Strömberg; Eckhard Wolf; Wolfgang Wurst; Martin Hrabě de Angelis; Johan Alsiö; Lore Becker; Nicole Ehrhardt; Ralf Elvert; Robert Fredriksson; Helmut Fuchs; Valérie Gailus-Durner; Wolfgang Hans; Sabine M Hölter; Josefin A Jacobsson; Martin Klingenspor; Anica Klockars; Thomas Klopstock; Allen S Levine; Claude Marcus; Manfred W Kilimann
Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans.
PLoS genetics 2012;8(3):e1002568.
2012: Markus Sällman Almén; Nathalie Bringeland; Robert Fredriksson; Helgi B Schiöth
The dispanins: a novel gene family of ancient origin that contains 14 human members.
PloS one 2012;7(2):e31961.
2011: Smitha Sreedharan; Olga Stephansson; Wolfgang Sommer; Markus Almén; Valeria P Carlini; Susana R de Barioglio; Robert Fredriksson; Tatjana Haitina; Markus Heilig; Helgi B Schiöth
The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus.
The FEBS journal 2011;278(24):4881-94.
2011: Karl Nordström; Markus Almén; Monika M Edstam; Robert Fredriksson; Helgi B Schiöth
Independent HHsearch, Needleman--Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families.
Molecular biology and evolution 2011;28(9):2471-80.
2011: Jonathan Cedernaes; Robert Fredriksson; Allen S Levine; Olof Nylander; Pawel K Olszewski; Markus Almén; Olga Stephansson; Helgi B Schiöth
Comprehensive analysis of localization of 78 solute carrier genes throughout the subsections of the rat gastrointestinal tract.
Biochemical and biophysical research communications 2011;411(4):702-7.
2011: Maria G A Hägglund; Smitha Sreedharan; Victor C O Nilsson; Jafar H A Shaik; Ingrid M Almkvist; Sofi Bäcklin; Orjan Wrange; Robert Fredriksson
Identification of SLC38A7 (SNAT7) protein as a glutamine transporter expressed in neurons.
The Journal of biological chemistry 2011;286(23):20500-11.
2011: Christian Benedict; Josefin A Jacobsson; Elina Rönnemaa; Markus Almén; Samantha Brooks; Bernd Schultes; Robert Fredriksson; Lars Lannfelt; Lena Kilander; Helgi B Schiöth
The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men.
Neurobiology of aging 2011;32(6):1159.e1-5.
2011: Pawel K Olszewski; Robert Fredriksson; Jenny D Eriksson; Anaya Mitra; Katarzyna J Radomska; Blake A Gosnell; Maria N Solvang; Allen S Levine; Helgi B Schiöth
Fto colocalizes with a satiety mediator oxytocin in the brain and upregulates oxytocin gene expression.
Biochemical and biophysical research communications 2011;408(3):422-6.
2011: Pawel K Olszewski; Katarzyna J Radomska; Kedar Ghimire; Anica Klockars; Caroline Ingman; Agnieszka M Olszewska; Robert Fredriksson; Allen S Levine; Helgi B Schiöth
Fto immunoreactivity is widespread in the rodent brain and abundant in feeding-related sites, but the number of Fto-positive cells is not affected by changes in energy balance.
Physiology & behavior 2011;103(2):248-53.
2011: Pär J Höglund; Karl Nordström; Helgi B Schiöth; Robert Fredriksson
The solute carrier families have a remarkably long evolutionary history with the majority of the human families present before divergence of Bilaterian species.
Molecular biology and evolution 2011;28(4):1531-41.
2011: Josefin A Jacobsson; Markus Almén; Christian Benedict; Lilia A Hedberg; Karl Michaëlsson; Samantha Brooks; Joel Kullberg; Tomas Axelsson; Lars Johansson; Håkan Ahlström; Robert Fredriksson; Lars Lind; Helgi B Schiöth
Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly.
PloS one 2011;6(5):e20158.
2011: Åke Västermark; Martin W Simmen; Markus Almén; Robert Fredriksson; Helgi B Schiöth
Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae.
BMC evolutionary biology 2011;11():123.
2010: Josefin A Jacobsson; Olga Stephansson; Robert Fredriksson
C6ORF192 forms a unique evolutionary branch among solute carriers (SLC16, SLC17, and SLC18) and is abundantly expressed in several brain regions.
Journal of molecular neuroscience : MN 2010;41(2):230-42.
2010: Helgi B Schiöth; Karl Nordström; Robert Fredriksson
The adhesion GPCRs; gene repertoire, phylogeny and evolution.
Advances in experimental medicine and biology 2010;706():1-13.
2010: Tobias Hill; Karl Nordström; Mikael Thollesson; Tommy M Säfström; Andreas K E Vernersson; Robert Fredriksson; Helgi B Schiöth
SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees.
BMC evolutionary biology 2010;10():42.
2010: Smitha Sreedharan; Jafar H A Shaik; Pawel K Olszewski; Allen S Levine; Helgi B Schiöth; Robert Fredriksson
Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression.
BMC genomics 2010;11():17.
2009: Karl Nordström; Majd A I Mirza; Markus Almén; David E I Gloriam; Robert Fredriksson; Helgi B Schiöth
Critical evaluation of the FANTOM3 non-coding RNA transcripts.
Genomics 2009;94(3):169-76.
2009: Johan Alsiö; Erika Roman; P K Olszewski; P Jonsson; Robert Fredriksson; A S Levine; B J Meyerson; Anna-Lena Hulting; Jonas Lindblom; Helgi B Schiöth
Inverse association of high-fat diet preference and anxiety-like behavior: a putative role for urocortin 2.
Genes, brain, and behavior 2009;8(2):193-202.
2009: Tomas A Larsson; Boon-Hui Tay; Görel Sundström; Robert Fredriksson; Sydney Brenner; Dan Larhammar; Byrappa Venkatesh
Neuropeptide Y-family peptides and receptors in the elephant shark, Callorhinchus milii confirm gene duplications before the gnathostome radiation.
Genomics 2009;93(3):254-60.
2009: Asa Wallén-Mackenzie; Karin Nordenankar; Kim Fejgin; Malin C Lagerström; Lina Emilsson; Robert Fredriksson; Caroline Wass; Daniel Andersson; Emil Egecioglu; My Andersson; Joakim Strandberg; Orjan Lindhe; Helgi B Schiöth; Karima Chergui; Eric Hanse; Bengt Långström; Anders Fredriksson; Lennart Svensson; Erika Roman; Klas Kullander
Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(7):2238-51.
2009: Pawel K Olszewski; Timothy J Shaw; Martha K Grace; Catherine E Höglund; Robert Fredriksson; Helgi B Schiöth; Allen S Levine
Complexity of neural mechanisms underlying overconsumption of sugar in scheduled feeding: involvement of opioids, orexin, oxytocin and NPY.
Peptides 2009;30(2):226-33.
2009: Josefin A Jacobsson; Ulf Risérus; Tomas Axelsson; Lars Lannfelt; Helgi B Schiöth; Robert Fredriksson
The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924.
BMC medical genetics 2009;10():131.
2009: Pawel K Olszewski; Robert Fredriksson; Agnieszka M Olszewska; Olga Stephansson; Johan Alsiö; Katarzyna J Radomska; Allen S Levine; Helgi B Schiöth
Hypothalamic FTO is associated with the regulation of energy intake not feeding reward.
BMC neuroscience 2009;10():129.
2009: Markus Almén; Karl Nordström; Robert Fredriksson; Helgi B Schiöth
Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin.
BMC biology 2009;7():50.
2009: Tatjana Haitina; Robert Fredriksson; Steven M Foord; Helgi B Schiöth; David E I Gloriam
The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents.
BMC genomics 2009;10():24.
2008: Robert Fredriksson; Karl Nordström; Olga Stephansson; Maria G A Hägglund; Helgi B Schiöth
The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families.
FEBS letters 2008;582(27):3811-6.
2008: Andreas Johansson; Robert Fredriksson; Sonja Winnergren; Anna-Lena Hulting; Helgi B Schiöth; Jonas Lindblom
The relative impact of chronic food restriction and acute food deprivation on plasma hormone levels and hypothalamic neuropeptide expression.
Peptides 2008;29(9):1588-95.
2008: Björn E Sundberg; Elin Wååg; Josefin A Jacobsson; Olga Stephansson; Juris Rumaks; Simons Svirskis; Johan Alsiö; Erika Roman; Ted Ebendal; Vija Klusa; Robert Fredriksson
The evolutionary history and tissue mapping of amino acid transporters belonging to solute carrier families SLC32, SLC36, and SLC38.
Journal of molecular neuroscience : MN 2008;35(2):179-93.
2008: Robert Fredriksson; Maria Hägglund; pawel olszewski; Olga Stephansson; Josefin A Jacobsson; Agnieszka M Olszewska; Allen S Levine; Jonas Lindblom; Helgi B Schiöth
The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain.
Endocrinology 2008;149(5):2062-71.
2008: Josefin A Jacobsson; Pernilla Danielsson; Victoria Svensson; Janis Klovins; Ulf Gyllensten; Claude Marcus; Helgi B Schiöth; Robert Fredriksson
Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes.
Biochemical and biophysical research communications 2008;368(3):476-82.
2008: Erik Pettersson; Pawel Zajac; Patrik L Ståhl; Josefin A Jacobsson; Robert Fredriksson; Claude Marcus; Helgi B Schiöth; Joakim Lundeberg; Afshin Ahmadian
Allelotyping by massively parallel pyrosequencing of SNP-carrying trinucleotide threads.
Human mutation 2008;29(2):323-9.
2008: Chris Pickering; Maria Hägglund; Joanna Szmydynger-Chodobska; Fernanda Marques; Joana A Palha; Linn Waller; Adam Chodobski; Robert Fredriksson; Malin C Lagerström; Helgi B Schiöth
The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury.
BMC neuroscience 2008;9():97.
2008: Tatjana Haitina; Fredrik Olsson; Olga Stephansson; Johan Alsiö; Erika Roman; Ted Ebendal; Helgi B Schiöth; Robert Fredriksson
Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat.
BMC neuroscience 2008;9():43.
2008: Karl Nordström; Robert Fredriksson; Helgi B Schiöth
The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors.
BMC evolutionary biology 2008;8():9.
2007: Josefin A Jacobsson; Tatjana Haitina; Jonas Lindblom; Robert Fredriksson
Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family.
Genomics 2007;90(5):595-609.
2007: Thóra K Bjarnadóttir; Robert Fredriksson; Helgi B Schiöth
The adhesion GPCRs: a unique family of G protein-coupled receptors with important roles in both central and peripheral tissues.
Cellular and molecular life sciences : CMLS 2007;64(16):2104-19.
2007: Davids Fridmanis; Robert Fredriksson; Ivo Kapa; Helgi B Schiöth; Janis Klovins
Formation of new genes explains lower intron density in mammalian Rhodopsin G protein-coupled receptors.
Molecular phylogenetics and evolution 2007;43(3):864-80.
2007: H B Schiöth; Karl Nordström; Robert Fredriksson
Mining the gene repertoire and ESTs for G protein-coupled receptors with evolutionary perspective.
Acta physiologica (Oxford, England) 2007;190(1):21-31.
2007: Carl-Johan Rubin; Helena Brändström; Dominic Wright; Susanne Kerje; Ulrika Gunnarsson; Karin Schutz; Robert Fredriksson; Per Jensen; Leif Andersson; Claes Ohlsson; Hans Mallmin; Sune Larsson; Andreas Kindmark
Quantitative trait loci for BMD and bone strength in an intercross between domestic and wildtype chickens.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22(3):375-84.
2007: Thóra K Bjarnadóttir; Kristín Geirardsdóttir; Malena Ingemansson; Majd A I Mirza; Robert Fredriksson; Helgi B Schiöth
Identification of novel splice variants of Adhesion G protein-coupled receptors.
Gene 2007;387(1-2):38-48.
2007: David E I Gloriam; Robert Fredriksson; Helgi B Schiöth
The G protein-coupled receptor subset of the rat genome.
BMC genomics 2007;8():338.
2007: Tatjana Haitina; Janis Klovins; Akiyoshi Takahashi; Maja Löwgren; Aneta Ringholm; Johan Enberg; Hiroshi Kawauchi; Earl T Larson; Robert Fredriksson; Helgi B Schiöth
Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes.
BMC evolutionary biology 2007;7():101.
2006: Tatjana Haitina; Jonas Lindblom; Thomas Renström; Robert Fredriksson
Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system.
Genomics 2006;88(6):779-90.
2006: Karl Nordström; Majd A I Mirza; Thomas P Larsson; David E I Gloriam; Robert Fredriksson; Helgi B Schiöth
Comprehensive comparisons of the current human, mouse, and rat RefSeq, Ensembl, EST, and FANTOM3 datasets: identification of new human genes with specific tissue expression profile.
Biochemical and biophysical research communications 2006;348(3):1063-74.
2006: Thóra K Bjarnadóttir; David E I Gloriam; Sofia H Hellstrand; Helena Kristiansson; Robert Fredriksson; Helgi B Schiöth
Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse.
Genomics 2006;88(3):263-73.
2006: Malin C Lagerström; Anders R Hellström; David E I Gloriam; Thomas P Larsson; Helgi B Schiöth; Robert Fredriksson
The G protein-coupled receptor subset of the chicken genome.
PLoS computational biology 2006;2(6):e54.
2006: Tomas A Larsson; Earl T Larson; Robert Fredriksson; J Michael Conlon; Dan Larhammar
Characterization of NPY receptor subtypes Y2 and Y7 in rainbow trout Oncorhynchus mykiss.
Peptides 2006;27(6):1320-7.
2006: Torun Bromée; Paula Sjödin; Robert Fredriksson; Timothy Boswell; Tomas A Larsson; Erik Salaneck; Rima Zoorob; Nina Mohell; Dan Larhammar
Neuropeptide Y-family receptors Y6 and Y7 in chicken. Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region.
The FEBS journal 2006;273(9):2048-63.
2006: Robert Fredriksson; Paula Sjödin; Earl T Larson; J Michael Conlon; Dan Larhammar
Cloning and characterization of a zebrafish Y2 receptor.
Regulatory peptides 2006;133(1-3):32-40.
2006: Jonas Lindblom; Andreas Johansson; Andreas Holmgren; Elisabeth Grandin; Carina Nedergård; Robert Fredriksson; Helgi B Schiöth
Increased mRNA levels of tyrosine hydroxylase and dopamine transporter in the VTA of male rats after chronic food restriction.
The European journal of neuroscience 2006;23(1):180-6.
2005: Thóra K Bjarnadóttir; Robert Fredriksson; Helgi B Schiöth
The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors.
Gene 2005;362():70-84.
2005: Höglund Pär; Dijana Adzic; Sara J Scicluna; Jonas Lindblom; Robert Fredriksson
The repertoire of solute carriers of family 6: identification of new human and rodent genes.
Biochemical and biophysical research communications 2005;336(1):175-89.
2005: Helgi B Schiöth; Tatjana Haitina; Maria K Ling; Aneta Ringholm; Robert Fredriksson; José Miguel Cerdá-Reverter; Janis Klovins
Evolutionary conservation of the structural, pharmacological, and genomic characteristics of the melanocortin receptor subtypes.
Peptides 2005;26(10):1886-900.
2005: Per Jensen; Linda J Keeling; Karin Schütz; Leif Andersson; P Mormède; Helena Brändström; Björn Forkman; Susanne Kerje; Robert Fredriksson; C Ohlsson; S Larsson; H Mallmin; Andreas Kindmark
Feather pecking in chickens is genetically related to behavioural and developmental traits.
Physiology & behavior 2005;86(1-2):52-60.
2005: Christian G Murray; Thomas P Larsson; Tobias Hill; Rikard Björklind; Robert Fredriksson; Helgi B Schiöth
Evaluation of EST-data using the genome assembly.
Biochemical and biophysical research communications 2005;331(4):1566-76.
2005: Malin C Lagerström; Robert Fredriksson; Thóra K Bjarnadóttir; Davids Fridmanis; Tomas Holmquist; Jan Andersson; Yi-Lin Yan; Terje Raudsepp; Rima Zoorob; Jyrki Kukkonen; Lars-Gustav Lundin; Janis Klovins; Bhanu P Chowdhary; John H Postlethwait; Helgi B Schiöth
Origin of the prolactin-releasing hormone (PRLH) receptors: evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution.
Genomics 2005;85(6):688-703.
2005: Helgi B Schiöth; Robert Fredriksson
The GRAFS classification system of G-protein coupled receptors in comparative perspective.
General and comparative endocrinology 2005;142(1-2):94-101.
2005: David E I Gloriam; Thóra K Bjarnadóttir; Yi-Lin Yan; John H Postlethwait; Helgi B Schiöth; Robert Fredriksson
The repertoire of trace amine G-protein-coupled receptors: large expansion in zebrafish.
Molecular phylogenetics and evolution 2005;35(2):470-82.
2005: Robert Fredriksson; Helgi B Schiöth
The repertoire of G-protein-coupled receptors in fully sequenced genomes.
Molecular pharmacology 2005;67(5):1414-25.
2005: David E I Gloriam; Helgi B Schiöth; Robert Fredriksson
Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship.
Biochimica et biophysica acta 2005;1722(3):235-46.
2005: Malin C Lagerström; Robert Fredriksson; T K Bjarnadottir; Helgi B Schiöth
The ancestry of the prolactin-releasing hormone precursor.
Annals of the New York Academy of Sciences 2005;1040():368-70.
2005: David E I Gloriam; Thóra K Bjarnadóttir; Helgi B Schiöth; Robert Fredriksson
High species variation within the repertoire of trace amine receptors.
Annals of the New York Academy of Sciences 2005;1040():323-7.
2005: Thóra K Bjarnadóttir; Helgi B Schiöth; Robert Fredriksson
The phylogenetic relationship of the glutamate and pheromone G-protein-coupled receptors in different vertebrate species.
Annals of the New York Academy of Sciences 2005;1040():230-3.
2005: Robert Fredriksson; Malin C Lagerström; Helgi B Schiöth
Expansion of the superfamily of G-protein-coupled receptors in chordates.
Annals of the New York Academy of Sciences 2005;1040():89-94.
2005: Thomas P Larsson; Christian G Murray; Tobias Hill; Robert Fredriksson; Helgi B Schiöth
Comparison of the current RefSeq, Ensembl and EST databases for counting genes and gene discovery.
FEBS letters 2005;579(3):690-8.
2005: Jonas Lindblom; Tatjana Haitina; Robert Fredriksson; Helgi B Schiöth
Differential regulation of nuclear receptors, neuropeptides and peptide hormones in the hypothalamus and pituitary of food restricted rats.
Brain research. Molecular brain research 2005;133(1):37-46.
2004: Susanne Kerje; Preety Sharma; Ulrika Gunnarsson; Hyun Kim; Sonchita Bagchi; Robert Fredriksson; Karin Schütz; Per Jensen; Gunnar von Heijne; Ron Okimoto; Leif Andersson
The Dominant white, Dun and Smoky color variants in chicken are associated with insertion/deletion polymorphisms in the PMEL17 gene.
Genetics 2004;168(3):1507-18.
2004: Linda J Keeling; Leif Andersson; Karin Schütz; Susanne Kerje; Robert Fredriksson; Orjan Carlborg; Charles K Cornwallis; Tommaso Pizzari; Per Jensen
Chicken genomics: feather-pecking and victim pigmentation.
Nature 2004;431(7009):645-6.
2004: Thóra K Bjarnadóttir; Robert Fredriksson; Höglund Pär; David E I Gloriam; Malin C Lagerström; Helgi B Schiöth
The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.
Genomics 2004;84(1):23-33.
2004: Tatjana Haitina; Janis Klovins; Jan Andersson; Robert Fredriksson; Malin C Lagerström; Dan Larhammar; Earl T Larson; Helgi B Schiöth
Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes.
The Biochemical journal 2004;380(Pt 2):475-86.
2004: Janis Klovins; Tatjana Haitina; Davids Fridmanis; Zuzana Kilianova; Ivo Kapa; Robert Fredriksson; Nicole Gallo-Payet; Helgi B Schiöth
The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs.
Molecular biology and evolution 2004;21(3):563-79.
2004: Robert Fredriksson; Earl T Larson; Yi-Lin Yan; John H Postlethwait; Dan Larhammar
Novel neuropeptide Y Y2-like receptor subtype in zebrafish and frogs supports early vertebrate chromosome duplications.
Journal of molecular evolution 2004;58(1):106-14.
2003: Malin C Lagerström; Janis Klovins; Robert Fredriksson; Davids Fridmanis; Tatjana Haitina; Maria K Ling; Magnus M Berglund; Helgi B Schiöth
High affinity agonistic metal ion binding sites within the melanocortin 4 receptor illustrate conformational change of transmembrane region 3.
The Journal of biological chemistry 2003;278(51):51521-6.
2003: Robert Fredriksson; Höglund Pär; David E I Gloriam; Malin C Lagerström; Helgi B Schiöth
Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives.
FEBS letters 2003;554(3):381-8.
2003: Helgi B Schiöth; Malin C Lagerström; Hajime Watanobe; Logi Jonsson; Anna Valeria Vergoni; Aneta Ringholm; Jon O. Skarphedinsson; Gudrun V Skuladottir; Janis Klovins; Robert Fredriksson
Functional role, structure, and evolution of the melanocortin-4 receptor.
Annals of the New York Academy of Sciences 2003;994():74-83.
2003: Robert Fredriksson; Malin C Lagerström; Lars-Gustav Lundin; Helgi B Schiöth
The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints.
Molecular pharmacology 2003;63(6):1256-72.
2003: Helgi B Schiöth; Terje Raudsepp; Aneta Ringholm; Robert Fredriksson; Sakae Takeuchi; Dan Larhammar; Bhanu P Chowdhary
Remarkable synteny conservation of melanocortin receptors in chicken, human, and other vertebrates.
Genomics 2003;81(5):504-9.
2003: Maria K Ling; Malin C Lagerström; Robert Fredriksson; Ronald Okimoto; Nicholas I Mundy; Sakae Takeuchi; Helgi B Schiöth
Association of feather colour with constitutively active melanocortin 1 receptors in chicken.
European journal of biochemistry / FEBS 2003;270(7):1441-9.
2003: Earl T Larson; Robert Fredriksson; Sara R T Johansson; Dan Larhammar
Cloning, pharmacology, and distribution of the neuropeptide Y-receptor Yb in rainbow trout.
Peptides 2003;24(3):385-95.
2003: Robert Fredriksson; David E I Gloriam; Höglund Pär; Malin C Lagerström; Helgi B Schiöth
There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini.
Biochemical and biophysical research communications 2003;301(3):725-34.
2003: Aneta Ringholm; Janis Klovins; Robert Fredriksson; Natalia Poliakova; Earl T Larson; Jyrki Kukkonen; Dan Larhammar; Helgi B Schiöth
Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system.
European journal of biochemistry / FEBS 2003;270(2):213-21.
2002: Robert Fredriksson; Malin C Lagerström; Höglund Pär; Helgi B Schiöth
Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.
FEBS letters 2002;531(3):407-14.
2002: Aneta Ringholm; Robert Fredriksson; Natalia Poliakova; Yi-Lin Yan; John H Postlethwait; Dan Larhammar; Helgi B Schiöth
One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacology.
Journal of neurochemistry 2002;82(1):6-18.
2002: Magnus M Berglund; Robert Fredriksson; Erik Salaneck; Dan Larhammar
Reciprocal mutations of neuropeptide Y receptor Y2 in human and chicken identify amino acids important for antagonist binding.
FEBS letters 2002;518(1-3):5-9.
2001: Erik Salaneck; Robert Fredriksson; Earl T Larson; J Michael Conlon; Dan Larhammar
A neuropeptide Y receptor Y1-subfamily gene from an agnathan, the European river lamprey. A potential ancestral gene.
European journal of biochemistry / FEBS 2001;268(23):6146-54.
1999: P Starbäck; Ingrid Lundell; Robert Fredriksson; Magnus M Berglund; Yi-Lin Yan; A Wraith; Charlotte Söderberg; John H Postlethwait; Dan Larhammar
Neuropeptide Y receptor subtype with unique properties cloned in the zebrafish: the zYa receptor.
Brain research. Molecular brain research 1999;70(2):242-52.