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Ralph Freedman
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43
Kavanagh, John
37
Edwards, Creighton
33
Kudelka, Andrzej
29
Verschraegen, Claire
26
Platsoucas, Chris
16
Ioannides, Constantin
12
Nash, Michael
11
Melichar, Bohuslav
10
Wharton, Taylor
8
Lenzi, Renato
8
Patenia, Rebecca
8
Gershenson, David
8
Atkinson, Neely
7
Hu, Wei
7
Quadri, Syed
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All Publications
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2009: Schmeler Kathleen M; Vadhan-Raj Saroj; Ramirez Pedro T; Apte Sachin M; Cohen Lorenzo; Bassett Roland L; Iyer Revathy B; Wolf Judith K; Levenback Charles L; Gershenson David M; Freedman Ralph S
A phase II study of GM-CSF and rIFN-gamma1b plus carboplatin for the treatment of recurrent, platinum-sensitive ovarian, fallopian tube and primary peritoneal cancer.
Gynecologic oncology 2009;113(2):210-5.
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2009: Kobayashi Ryuji; Deavers Michael; Patenia Rebecca; Rice-Stitt Travis; Halbe Jeremy; Gallardo Stacie; Freedman Ralph S
14-3-3 zeta protein secreted by tumor associated monocytes/macrophages from ascites of epithelial ovarian cancer patients.
Cancer immunology, immunotherapy : CII 2009;58(2):247-58.
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2008: Freedman Ralph S; Ma Qing; Wang Ena; Gallardo Stacie T; Gordon Ilyssa O; Shin Jeong Won; Jin Ping; Stroncek David; Marincola Francesco M
Migration deficit in monocyte-macrophages in human ovarian cancer.
Cancer immunology, immunotherapy : CII 2008;57(5):635-45.
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2007: Freedman Ralph S; Wang Ena; Voiculescu Sonia; Patenia Rebecca; Bassett Roland L; Deavers Michael; Marincola Francesco M; Yang Peiying; Newman Robert A
Comparative analysis of peritoneum and tumor eicosanoids and pathways in advanced ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(19):5736-44.
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2007: Auzenne Edmond; Ghosh Sukhen C; Khodadadian Mojgan; Rivera Belinda; Farquhar David; Price Roger E; Ravoori Murali; Kundra Vikas; Freedman Ralph S; Klostergaard Jim
Hyaluronic acid-paclitaxel: antitumor efficacy against CD44(+) human ovarian carcinoma xenografts.
Neoplasia (New York, N.Y.) 2007;9(6):479-86.
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2007: Freedman Ralph S; Markman Maurie
Food and drug administration expanded access to treatment: implications for oncology patients.
Cancer 2007;109(11):2157-60.
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2007: Melichar Bohuslav; Patenia Rebecca; Gallardo Stacie; Melicharová Karolina; Hu Wei; Freedman Ralph S
Expression of CD40 and growth-inhibitory activity of CD40 ligand in ovarian cancer cell lines.
Gynecologic oncology 2007;104(3):707-13.
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2007: Lenzi Renato; Edwards Robert; June Carl; Seiden Michael V; Garcia Michael E; Rosenblum Michael; Freedman Ralph S
Phase II study of intraperitoneal recombinant interleukin-12 (rhIL-12) in patients with peritoneal carcinomatosis (residual disease < 1 cm) associated with ovarian cancer or primary peritoneal carcinoma.
Journal of translational medicine 2007;5():66.
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2006: Wang X; Fu S; Freedman R S; Liu J; Kavanagh J J
Immunobiology of gestational trophoblastic diseases.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2006;16(4):1500-15.
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2006: Basil Christopher F; Zhao Yingdong; Zavaglia Katia; Jin Ping; Panelli Monica C; Voiculescu Sonia; Mandruzzato Susanna; Lee Hueling M; Seliger Barbara; Freedman Ralph S; Taylor Phil R; Hu Nan; Zanovello Paola; Marincola Francesco M; Wang Ena
Common cancer biomarkers.
Cancer research 2006;66(6):2953-61.
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2006: Gordon Ilyssa O; Freedman Ralph S
Defective antitumor function of monocyte-derived macrophages from epithelial ovarian cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(5):1515-24.
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2006: Wang X; Fu S; Freedman R S; Kavanagh J J
Venous thromboembolism syndrome in gynecological cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2006;16 Suppl 1():458-71.
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2006: Wang Xipeng; Deavers Michael; Patenia Rebecca; Bassett Roland L; Mueller Peter; Ma Qing; Wang Ena; Freedman Ralph S
Monocyte/macrophage and T-cell infiltrates in peritoneum of patients with ovarian cancer or benign pelvic disease.
Journal of translational medicine 2006;4():30.
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2006: Apte Sachin M; Vadhan-Raj Saroj; Cohen Lorenzo; Bassett Roland L; Gordon Ilyssa O; Levenback Charles F; Ramirez Pedro T; Gallardo Stacie T; Patenia Rebecca S; Garcia Michael E; Iyer Revathy B; Freedman Ralph S
Cytokines, GM-CSF and IFNgamma administered by priming and post-chemotherapy cycling in recurrent ovarian cancer patients receiving carboplatin.
Journal of translational medicine 2006;4():16.
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2005: Wang Xipeng; Wang Ena; Kavanagh John J; Freedman Ralph S
Ovarian cancer, the coagulation pathway, and inflammation.
Journal of translational medicine 2005;3():25.
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2005: Pappas John; Jung Weon-Ju; Barda Angeliki K; Lin Wan L; Fincke John E; Purev Enkhtuya; Radu Maria; Gaughan John; Helm C William; Hernandez Enrique; Freedman Ralph S; Platsoucas Chris D
Substantial proportions of identical beta-chain T-cell receptor transcripts are present in epithelial ovarian carcinoma tumors.
Cellular immunology 2005;234(2):81-101.
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2005: See H T; Freedman R S; Kudelka A P; Burke T W; Gershenson D M; Tangjitgamol S; Kavanagh J J
Retrospective review: re-treatment of patients with ovarian cancer with carboplatin after platinum resistance.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2005;15(2):209-16.
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2005: Wang Ena; Ngalame Yvonne; Panelli Monica C; Nguyen-Jackson Hoainam; Deavers Michael; Mueller Peter; Hu Wei; Savary Cherylyn A; Kobayashi Ryuji; Freedman Ralph S; Marincola Francesco M
Peritoneal and subperitoneal stroma may facilitate regional spread of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(1):113-22.
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2005: Hu Wei; Kavanagh John J; Deaver Michael; Johnston Dennis A; Freedman Ralph S; Verschraegen Claire F; Sen Subrata
Frequent overexpression of STK15/Aurora-A/BTAK and chromosomal instability in tumorigenic cell cultures derived from human ovarian cancer.
Oncology research 2005;15(1):49-57.
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2004: Donato M L; Aleman A; Champlin R E; Saliba R M; Wharton J T; Burke T W; Bodurka D C; Bevers M W; Levenback C F; Wolf J K; Bast R C; Freedman R S; Ippoliti C; Brewer M; Gajewski J L; Gershenson D M
Analysis of 96 patients with advanced ovarian carcinoma treated with high-dose chemotherapy and autologous stem cell transplantation.
Bone marrow transplantation 2004;33(12):1219-24.
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2004: Melichar Bohuslav; Konopleva Marina; Hu Wei; Melicharova Karolina; Andreeff Michael; Freedman Ralph S
Growth-inhibitory effect of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, on ovarian carcinoma cell lines not dependent on peroxisome proliferator-activated receptor-gamma expression.
Gynecologic oncology 2004;93(1):149-54.
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2004: Borchardt Paul E; Vriesendorp Huibert M; Freedman Ralph S; Quadri Syed M
Intralesional radioimmunotherapy with Yttrium-90-labeled human monoclonal IgM in nude mice bearing human tumor xenografts.
Cancer biotherapy & radiopharmaceuticals 2004;19(1):43-51.
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2003: Freedman Ralph S; Vadhan-Raj Saroj; Butts Cherie; Savary Cherylyn; Melichar Bohuslav; Verschraegen Claire; Kavanagh John J; Hicks Marshall E; Levy Lawrence B; Folloder Jody K; Garcia Michael E
Pilot study of Flt3 ligand comparing intraperitoneal with subcutaneous routes on hematologic and immunologic responses in patients with peritoneal carcinomatosis and mesotheliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(14):5228-37.
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2003: Hu Wei; Wu WeiGuo; Verschraegen Claire F; Chen Ling; Mao Li; Yeung Sai-Ching Jim; Kudelka Andrzej P; Freedman Ralph S; Kavanagh John J
Proteomic identification of heat shock protein 70 as a candidate target for enhancing apoptosis induced by farnesyl transferase inhibitor.
Proteomics 2003;3(10):1904-11.
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2003: Melichar B; Savary C A; Patenia R; Templin S; Melicharova K; Freedman R S
Phenotype and antitumor activity of ascitic fluid monocytes in patients with ovarian carcinoma.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2003;13(4):435-43.
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2003: Platsoucas Chris D; Fincke John E; Pappas John; Jung Weon-Ju; Heckel Mark; Schwarting Roland; Magira Eleni; Monos Dimitri; Freedman Ralph S
Immune responses to human tumors: development of tumor vaccines.
Anticancer research 2003;23(3A):1969-96.
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2003: Melichar Bohuslav; Lenzi Renato; Rosenblum Michael; Kudelka Andrzej P; Kavanagh John J; Melicharova Karolina; Templin Stacie; Garcia Michael E; Abbruzzese James L; Freedman Ralph S
Intraperitoneal fluid neopterin, nitrate, and tryptophan after regional administration of interleukin-12.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2003;26(3):270-6.
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2003: Verschraegen Claire F; Hu Wei; Du Yu; Mendoza John; Early Janet; Deavers Michael; Freedman Ralph S; Bast Robert C; Kudelka Andrzej P; Kavanagh John J; Giovanella Beppino C
Establishment and characterization of cancer cell cultures and xenografts derived from primary or metastatic Mullerian cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):845-52.
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2002: Lenzi Renato; Rosenblum Michael; Verschraegen Claire; Kudelka Andrzej P; Kavanagh John J; Hicks Marshall E; Lang Eric A; Nash Michael A; Levy Lawrence B; Garcia Michael E; Platsoucas Chris D; Abbruzzese James L; Freedman Ralph S
Phase I study of intraperitoneal recombinant human interleukin 12 in patients with Müllerian carcinoma, gastrointestinal primary malignancies, and mesothelioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3686-95.
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2002: Gordinier M E; Kudelka A P; Kavanagh J J; Wharton J T; Freedman R S
Thiotepa in combination with cisplatin for primary epithelial ovarian cancer: a phase II study.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2002;12(6):710-4.
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2002: Vadhan-Raj Saroj; Kavanagh John J; Freedman Ralph S; Folloder Jody; Currie Laura M; Bueso-Ramos Carlos; Verschraegen Claire F; Narvios Aida B; Connor Jerome; Hoots William K; Broemeling Lyle D; Lichtiger Benjamin
Safety and efficacy of transfusions of autologous cryopreserved platelets derived from recombinant human thrombopoietin to support chemotherapy-associated severe thrombocytopenia: a randomised cross-over study.
Lancet 2002;359(9324):2145-52.
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2002: Nash Michael A; Deavers Michael T; Freedman Ralph S
The expression of decorin in human ovarian tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1754-60.
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2002: Hwu Patrick; Freedman Ralph S
The immunotherapy of patients with ovarian cancer.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2002;25(3):189-201.
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2002: Hu Wei; Wu Weiguo; Yeung Sai-Ching Jim; Freedman Ralph S; Kavanagh John J; Verschraegen Claire F
Increased expression of heat shock protein 70 in adherent ovarian cancer and mesothelioma following treatment with manumycin, a farnesyl transferase inhibitor.
Anticancer research 2002;22(2A):665-72.
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2002: Hu Wei; Verschraegen C F; Wu W G; Nash M; Freedman R S; Kudelka A; Kavanagh J J
Activity of ALRT 1550, a new retinoid, with interferon-gamma on ovarian cancer cell lines.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2002;12(2):202-7.
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2001: Zavadova E; Savary C A; Templin S; Verschraegen C F; Freedman R S
Maturation of dendritic cells from ovarian cancer patients.
Cancer chemotherapy and pharmacology 2001;48(4):289-96.
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2001: Donato M L; Gershenson D M; Wharton J T; Ippoliti C M; Aleman A S; Bodurka-Bevers D; Bevers M W; Burke T W; Levenback C F; Wolf J K; Freedman R S; Bast R C; Gajewski J L; Champlin R E
High-dose topotecan, melphalan, and cyclophosphamide (TMC) with stem cell support: a new regimen for the treatment of advanced ovarian cancer.
Gynecologic oncology 2001;82(3):420-6.
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2001: Azevedo P; Verschraegen C F; Kavanagh J J; Kudelka A P; Freedman R S; Lu K; Deavers M T
Malignant mixed mesodermal tumor of the ovary treated with a cisplatin-irinotecan combination: case report.
European journal of gynaecological oncology 2001;22(5):319-21.
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2000: Freedman R S; Kudelka A P; Kavanagh J J; Verschraegen C; Edwards C L; Nash M; Levy L; Atkinson E N; Zhang H Z; Melichar B; Patenia R; Templin S; Scott W; Platsoucas C D
Clinical and biological effects of intraperitoneal injections of recombinant interferon-gamma and recombinant interleukin 2 with or without tumor-infiltrating lymphocytes in patients with ovarian or peritoneal carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(6):2268-78.
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2000: Hu W; Wu W; Nash M A; Freedman R S; Kavanagh J J; Verschraegen C F
Anomalies of the TGF-beta postreceptor signaling pathway in ovarian cancer cell lines.
Anticancer research 2000;20(2A):729-33.
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2000: Vadhan-Raj S; Verschraegen C F; Bueso-Ramos C; Broxmeyer H E; Kudelkà A P; Freedman R S; Edwards C L; Gershenson D; Jones D; Ashby M; Kavanagh J J
Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer.
Annals of internal medicine 2000;132(5):364-8.
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2000: Borchardt P E; Quadri S M; Freedman R S; Vriesendorp H M
Intraperitoneal radioimmunotherapy with human monoclonal IGM in nude mice with peritoneal carcinomatosis.
Cancer biotherapy & radiopharmaceuticals 2000;15(1):53-64.
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2000: Melichar B; Nash M A; Lenzi R; Platsoucas C D; Freedman R S
Expression of costimulatory molecules CD80 and CD86 and their receptors CD28, CTLA-4 on malignant ascites CD3+ tumour-infiltrating lymphocytes (TIL) from patients with ovarian and other types of peritoneal carcinomatosis.
Clinical and experimental immunology 2000;119(1):19-27.
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1999: Nash M A; Loercher A E; Freedman R S
In vitro growth inhibition of ovarian cancer cells by decorin: synergism of action between decorin and carboplatin.
Cancer research 1999;59(24):6192-6.
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1999: Loercher A E; Nash M A; Kavanagh J J; Platsoucas C D; Freedman R S
Identification of an IL-10-producing HLA-DR-negative monocyte subset in the malignant ascites of patients with ovarian carcinoma that inhibits cytokine protein expression and proliferation of autologous T cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(11):6251-60.
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1999: Gordinier M E; Zhang H Z; Patenia R; Levy L B; Atkinson E N; Nash M A; Katz R L; Platsoucas C D; Freedman R S
Quantitative analysis of transforming growth factor beta 1 and 2 in ovarian carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(9):2498-505.
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1999: Verschraegen C F; Gupta E; Loyer E; Kavanagh J J; Kudelka A P; Freedman R S; Edwards C L; Harris N; Steger M; Steltz V; Giovanella B C; Stehlin J S
A phase II clinical and pharmacological study of oral 9-nitrocamptothecin in patients with refractory epithelial ovarian, tubal or peritoneal cancer.
Anti-cancer drugs 1999;10(4):375-83.
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1999: Nash M A; Ferrandina G; Gordinier M; Loercher A; Freedman R S
The role of cytokines in both the normal and malignant ovary.
Endocrine-related cancer 1999;6(1):93-107.
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1999: Zavadova E; Loercher A; Verstovsek S; Verschraegen C F; Micksche M; Freedman R S
The role of macrophages in antitumor defense of patients with ovarian cancer.
Hematology/oncology clinics of North America 1999;13(1):135-44, ix.
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1998: Melichar B; Ferrandina G; Verschraegen C F; Loercher A; Abbruzzese J L; Freedman R S
Growth inhibitory effects of aromatic fatty acids on ovarian tumor cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(12):3069-76.
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1998: Nash M A; Lenzi R; Platsoucas C D; Freedman R S
RT-PCR quantitation of cytokine responses in vivo from specimens containing small numbers of cells during bioimmunotherapy.
Journal of immunological methods 1998;219(1-2):169-79.
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1998: Kudelka A P; Lenzi R; Atkinson E N; Levy L B; Freedman R S
Is ascitic fluid interleukin-12 an independent prognostic factor in ovarian cancer? The necessity of correction milligram P values for multiple comparisons.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(9):3208-9.
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1998: Freedman R S; Lenzi R; Kudelka A P; Lawrence D D; Rosenblum M; Platsoucas C D
Intraperitoneal immunotherapy of peritoneal carcinomatosis.
Cytokines, cellular & molecular therapy 1998;4(2):121-40.
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1998: Kudelka A P; Hasenburg A; Verschraegen C F; Edwards C L; Meyers C A; Varma D; Freedman R S; Forman A; Conrad C A; Grove W; Grothey A; Kavanagh J J
Phase II study of i.v. CI-980 in patients with advanced platinum refractory epithelial ovarian carcinoma.
Anti-cancer drugs 1998;9(5):405-9.
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1998: Nash M A; Lenzi R; Edwards C L; Kavanagh J J; Kudelka A P; Verschraegen C F; Platsoucas C D; Freedman R S
Differential expression of cytokine transcripts in human epithelial ovarian carcinoma by solid tumour specimens, peritoneal exudate cells containing tumour, tumour-infiltrating lymphocyte (TIL)-derived T cell lines and established tumour cell lines.
Clinical and experimental immunology 1998;112(2):172-80.
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1998: Melichar B; Savary C; Kudelka A P; Verschraegen C; Kavanagh J J; Edwards C L; Platsoucas C D; Freedman R S
Lineage-negative human leukocyte antigen-DR+ cells with the phenotype of undifferentiated dendritic cells in patients with carcinoma of the abdomen and pelvis.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(3):799-809.
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1998: Borchardt P E; Quadri S M; Freedman R S; Vriesendorp H M
Indium-111- and yttrium-90-labeled human monoclonal immunoglobulin M targeting of human ovarian cancer in mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(3):476-84.
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1998: Verschraegen C F; Natelson E A; Giovanella B C; Kavanagh J J; Kudelka A P; Freedman R S; Edwards C L; Ende K; Stehlin J S
A phase I clinical and pharmacological study of oral 9-nitrocamptothecin, a novel water-insoluble topoisomerase I inhibitor.
Anti-cancer drugs 1998;9(1):36-44.
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1998: Savary C A; Grazziutti M L; Melichar B; Przepiorka D; Freedman R S; Cowart R E; Cohen D M; Anaissie E J; Woodside D G; McIntyre B W; Pierson D L; Pellis N R; Rex J H
Multidimensional flow-cytometric analysis of dendritic cells in peripheral blood of normal donors and cancer patients.
Cancer immunology, immunotherapy : CII 1998;45(5):234-40.
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1997: Ferrandina G; Melichar B; Loercher A; Verschraegen C F; Kudelka A P; Edwards C L; Scambia G; Kavanagh J J; Abbruzzese J L; Freedman R S
Growth inhibitory effects of sodium phenylacetate (NSC 3039) on ovarian carcinoma cells in vitro.
Cancer research 1997;57(19):4309-15.
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1997: Kudelka A P; Levy T; Verschraegen C F; Edwards C L; Piamsomboon S; Termrungruanglert W; Freedman R S; Kaplan A L; Kieback D G; Meyers C A; Jaeckle K A; Loyer E; Steger M; Mante R; Mavligit G; Killian A; Tang R A; Gutterman J U; Kavanagh J J
A phase I study of TNP-470 administered to patients with advanced squamous cell cancer of the cervix.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(9):1501-5.
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1997: Borchardt P E; Quadri S M; Freedman R S; Vriesendorp H M
Intralesional radiolabeled human monoclonal IgM in human tumor xenografts.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1997;44(3):283-93.
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1997: Kudelka A P; Winn R; Edwards C L; Downey G; Greenberg H; Dakhil S R; Freedman R S; LoCoco S; Umbreit J; Delmore J E; Arbuck S; Loyer E; Gacrama P; Fueger R; Kavanagh J J
An update of a phase II study of paclitaxel in advanced or recurrent squamous cell cancer of the cervix.
Anti-cancer drugs 1997;8(7):657-61.
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1997: Kudelka A P; Siddik Z H; Tresukosol D; Edwards C L; Freedman R S; Madden T L; Rastogi R; Hord M; Kim E E; Tornos C; Mante R; Kavanagh J J
A phase II and pharmacokinetic study of enloplatin in patients with platinum refractory advanced ovarian carcinoma.
Anti-cancer drugs 1997;8(7):649-56.
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1997: Verschraegen C F; Levy T; Kudelka A P; Llerena E; Ende K; Freedman R S; Edwards C L; Hord M; Steger M; Kaplan A L; Kieback D; Fishman A; Kavanagh J J
Phase II study of irinotecan in prior chemotherapy-treated squamous cell carcinoma of the cervix.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(2):625-31.
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1996: Kooi S; Zhang H Z; Patenia R; Edwards C L; Platsoucas C D; Freedman R S
HLA class I expression on human ovarian carcinoma cells correlates with T-cell infiltration in vivo and T-cell expansion in vitro in low concentrations of recombinant interleukin-2.
Cellular immunology 1996;174(2):116-28.
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1996: Freedman R S; Gibbons J A; Giedlin M; Kudelka A P; Kavanagh J J; Edwards C L; Carrasco C H; Nash M A; Platsoucas C D
Immunopharmacology and cytokine production of a low-dose schedule of intraperitoneally administered human recombinant interleukin-2 in patients with advanced epithelial ovarian carcinoma.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1996;19(6):443-51.
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1996: Vriesendorp H M; Quadri S M; Jaeckle K A; Freedman R S; Cromeens D M
Proposal for translational analysis and development of clinical radiolabeled immunoglobulin therapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1996;41(2):151-61.
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1996: Piamsomboon S; Termrungruanglert W; Kudelka A P; Edwards C L; Freedman R S; Mountain C F; Delclos L; Aapro M S; DeCaro L; Bianca J; Verschraegen C F; Kavanagh J J
Prolonged stabilization of progressive squamous cell cancer of the cervix with interferon-alpha and 13-cis-retinoic acid: report of two cases and review of the literature.
Anti-cancer drugs 1996;7(7):800-4.
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1996: Quadri S M; Malik A B; Chu H B; Freedman R S; Vriesendorp H M
Intraperitoneal indium-111- and yttrium-90-labeled human IgM (AC6C3-2B12) in nude mice bearing peritoneal carcinomatosis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(9):1545-51.
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1996: Kudelka A P; Winn R; Edwards C L; Downey G; Greenberg H; Dakhil S R; Freedman R S; Loyer E; Rusinkiewicz J; Gacrama P; Fueger R; Kavanagh J J
Activity of paclitaxel in advanced or recurrent squamous cell cancer of the cervix.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(8):1285-8.
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1996: Verschraegen C F; Kudelka A P; Termrungruanglert W; de Leon C G; Edwards C L; Freedman R S; Kavanagh J J; Vadhan-Raj S
Effects of interleukin-1 alpha on ovarian carcinoma in patients with recurrent disease.
European journal of cancer (Oxford, England : 1990) 1996;32A(9):1609-11.
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1996: Freedman R S; Platsoucas C D; Deisseroth A B
Use of a retroviral vector to study the trafficking patterns of purified ovarian tumor infiltrating lymphocytes (TIL) used in intraperitoneal adoptive immunotherapy of ovarian cancer patients. A pilot study.
Human gene therapy 1996;7(11):1351-65.
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1996: Kudelka A P; Verschraegen C F; Levy T; Edwards C L; Fishman A; Freedman R S; Kaplan A; Kieback D G; Mante R; Ende K; Steger M; Kavanagh J J
Preliminary report of the activity of docetaxel in advanced or recurrent squamous cell cancer of the cervix.
Anti-cancer drugs 1996;7(4):398-401.
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1996: Fishman A; Kudelka A P; Tresukosol D; Edwards C L; Freedman R S; Kaplan A L; Girtanner R E; Kavanagh J J
Leuprolide acetate for treating refractory or persistent ovarian granulosa cell tumor.
The Journal of reproductive medicine 1996;41(6):393-6.
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1996: Kavanagh J J; Kudelka A P; de Leon C G; Tresukosol D; Hord M; Finnegan M B; Kim E E; Varma D; Forman A; Cohen P; Edwards C L; Freedman R S; Verschraegen C F
Phase II study of docetaxel in patients with epithelial ovarian carcinoma refractory to platinum.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(5):837-42.
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1996: Kudelka A P; Tresukosol D; Edwards C L; Freedman R S; Levenback C; Chantarawiroj P; Gonzalez de Leon C; Kim E E; Madden T; Wallin B; Hord M; Verschraegen C; Raber M; Kavanagh J J
Phase II study of intravenous topotecan as a 5-day infusion for refractory epithelial ovarian carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(5):1552-7.
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1996: Kudelka A P; Tresukosol D; Gonzalez de Leon C; Termrungruanglert W; Edwards C L; Freedman R S; Tornos C; Kavanagh J J
Paclitaxel in patients with platinum-resistant ovarian cancer: a selected review of literature and clinical experience.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet 1996;79(4):240-5.
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1996: Lin Y C; Kudelka A P; Lawrence D; Verschraegen C F; Kavanagh J J; Edwards C L; Mante R; Freedman R S
Transcatheter arterial embolization for the control of life-threatening pelvic hemorrhage in a patient with locally advanced cervix carcinoma.
European journal of gynaecological oncology 1996;17(6):480-3.
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1996: Freedman R S; Platsoucas C D
Immunotherapy for peritoneal ovarian carcinoma metastasis using ex vivo expanded tumor infiltrating lymphocytes.
Cancer treatment and research 1996;82():115-46.
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1996: Tresukosol D; Kudelka A P; Gonzales de Leon C; Edwards C L; Freedman R S; Mante R; Hord M; Kavanagh J J
Paclitaxel retreatment in patients with platinum and paclitaxel resistant ovarian cancer.
European journal of gynaecological oncology 1996;17(3):188-91.
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1995: Quadri S M; Malik A B; Tang X Z; Patenia R; Freedman R S; Vriesendorp H M
Preclinical analysis of intraperitoneal administration of 111In-labeled human tumor reactive monoclonal IgM AC6C3-2B12.
Cancer research 1995;55(23 Suppl):5736s-5742s.
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1995: Nash M A; Platsoucas C D; Wong B Y; Wong P M; Cottler-Fox M; Otto E; Freedman R S
Transduction of rIL-2 expanded CD4+ and CD8+ ovarian TIL-derived T cell lines with the G1Na (neor) replication-deficient retroviral vector.
Human gene therapy 1995;6(11):1379-89.
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1995: Kavanagh J J; Edwards C L; Freedman R S; Finnegan M B; Balat O; Tresukosol D; Burk K; Loechner S; Hord M; Franklin J L
A trial of lobaplatin (D-19466) in platinum-resistant ovarian cancer.
Gynecologic oncology 1995;58(1):106-9.
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1994: Coleman R L; Keeney E D; Freedman R S; Burke T W; Eifel P J; Rutledge F N
Radical hysterectomy for recurrent carcinoma of the uterine cervix after radiotherapy.
Gynecologic oncology 1994;55(1):29-35.
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1994: Freedman R S; Edwards C L; Kavanagh J J; Kudelka A P; Katz R L; Carrasco C H; Atkinson E N; Scott W; Tomasovic B; Templin S
Intraperitoneal adoptive immunotherapy of ovarian carcinoma with tumor-infiltrating lymphocytes and low-dose recombinant interleukin-2: a pilot trial.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1994;16(3):198-210.
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1994: Vadhan-Raj S; Kudelka A P; Garrison L; Gano J; Edwards C L; Freedman R S; Kavanagh J J
Effects of interleukin-1 alpha on carboplatin-induced thrombocytopenia in patients with recurrent ovarian cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(4):707-14.
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1994: Freedman R S; Tomasovic B; Templin S; Atkinson E N; Kudelka A; Edwards C L; Platsoucas C D
Large-scale expansion in interleukin-2 of tumor-infiltrating lymphocytes from patients with ovarian carcinoma for adoptive immunotherapy.
Journal of immunological methods 1994;167(1-2):145-60.
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1994: Chen P F; Freedman R S; Chernajovsky Y; Platsoucas C D
Amplification of immunoglobulin transcripts by the non-palindromic adaptor polymerase chain reaction (NPA-PCR). Nucleotide sequence analysis of two human monoclonal antibodies recognizing two cell surface antigens expressed in ovarian, cervix, breast, colon and other carcinomas.
Human antibodies and hybridomas 1994;5(3-4):131-42.
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1993: Kooi S; Freedman R S; Rodriguez-Villanueva J; Platsoucas C D
Cytokine production by T-cell lines derived from tumor-infiltrating lymphocytes from patients with ovarian carcinoma: tumor-specific immune responses and inhibition of antigen-independent cytokine production by ovarian tumor cells.
Lymphokine and cytokine research 1993;12(6):429-37.
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1993: Ioannides C G; Fisk B; Pollack M S; Frazier M L; Taylor Wharton J; Freedman R S
Cytotoxic T-cell clones isolated from ovarian tumour infiltrating lymphocytes recognize common determinants on non-ovarian tumour clones.
Scandinavian journal of immunology 1993;37(4):413-24.
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1992: Freedman R S; Ioannides C G; Mathioudakis G; Platsoucas C D
Novel immunologic strategies in ovarian carcinoma.
American journal of obstetrics and gynecology 1992;167(5):1470-8.
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1992: Ioannides C G; Fisk B; Tomasovic B; Pandita R; Aggarwal B B; Freedman R S
Induction of interleukin-2 receptor by tumor necrosis factor alpha on cultured ovarian tumor-associated lymphocytes.
Cancer immunology, immunotherapy : CII 1992;35(2):83-91.
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1991: Fromm G L; Freedman R S; Fritsche H A; Atkinson E N; Scott W
Sequentially administered ethinyl estradiol and medroxyprogesterone acetate in the treatment of refractory epithelial ovarian carcinoma in patients with positive estrogen receptors.
Cancer 1991;68(9):1885-9.
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1991: Ioannides C G; Freedman R S
Selective usage of TCR V beta in tumor-specific CTL lines isolated from ovarian tumor-associated lymphocytes.
Anticancer research 1991;11(5):1919-25.
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1991: Ioannides C G; Rashed S; Fisk B; Fan D; Itoh K; Freedman R S
Lymphocytes infiltrating ovarian malignant ascites: modulation of IL-2-induced proliferation by IL-4 and of selective increase in CD8+ T cells by TNF-alpha.
Lymphokine and cytokine research 1991;10(4):307-15.
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1991: Ioannides C G; Platsoucas C D; Rashed S; Wharton J T; Edwards C L; Freedman R S
Tumor cytolysis by lymphocytes infiltrating ovarian malignant ascites.
Cancer research 1991;51(16):4257-65.
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1991: Burke T W; Stringer C A; Morris M; Freedman R S; Gershenson D M; Kavanagh J J; Edwards C L
Prospective treatment of advanced or recurrent endometrial carcinoma with cisplatin, doxorubicin, and cyclophosphamide.
Gynecologic oncology 1991;40(3):264-7.
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1991: Ioannides C G; Freedman R S; Platsoucas C D; Rashed S; Kim Y P
Cytotoxic T cell clones isolated from ovarian tumor-infiltrating lymphocytes recognize multiple antigenic epitopes on autologous tumor cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(5):1700-7.
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1991: Freedman R S; Ioannides C G; Tomasovic B; Patenia R; Zhang H Z; Liang J C; Edwards C L
Development of a cell surface reacting human monoclonal antibody recognizing ovarian and certain other malignancies.
Hybridoma 1991;10(1):21-33.
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1991: Ioannides C G; Freedman R S; Patenia R; Bowen J M; Ward N E; O'Brian C A
Immunological effects of tumor vaccines: III. Influenza virus oncolysates inhibit the TPA induced activation of peripheral blood mononuclear cells.
In vivo (Athens, Greece) 1991;5(1):1-6.
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1991: Ioannides C G; Freedman R S
T cell responses to ovarian tumor vaccines: identification and significance for future immunotherapy.
International reviews of immunology 1991;7(4):349-64.
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1990: Riley L B; Pellis N R; Schantz S P; Freedman R S; Balch C M; Itoh K
Humoral modulation of lymphokine-activated killer (LAK)-cell induction in humans: IgG-related and non-IgG inhibitors in sera from cancer patients.
International journal of cancer. Journal international du cancer 1990;46(5):785-91.
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1990: Sandles L G; Freedman R S; Raber M N; Kavanagh J; Edwards C L; Scott W R; Wharton J T
Phase I evaluation of thio-TEPA in combination with cisplatin for advanced gynecologic malignancies.
Gynecologic oncology 1990;39(2):139-45.
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1990: Ioannides C G; Freedman R S; Liskamp R M; Ward N E; O'Brian C A
Inhibition of IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat by a novel peptide inhibitor of protein kinase C.
Cellular immunology 1990;131(1):242-52.
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1990: Ioannides C G; Platsoucas C D; Patenia R; Kim Y P; Bowen J M; Morris M; Edwards C; Wharton J T; Freedman R S
T-cell functions in ovarian cancer patients treated with viral oncolysates: I. Increased helper activity to immunoglobulins production.
Anticancer research 1990;10(3):645-53.
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1990: Ioannides C G; Platsoucas C D; Freedman R S
Immunological effects of tumor vaccines: II. T cell responses directed against cellular antigens in the viral oncolysates.
In vivo (Athens, Greece) 1990;4(1):17-24.
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1990: Lotzová E; Savary C A; Freedman R S; Edwards C L; Morris M
Comparison of recombinant-interleukin-2-activated peripheral blood and tumor-infiltrating lymphocytes of patients with epithelial ovarian carcinoma: cytotoxicity, growth kinetics and phenotype.
Cancer immunology, immunotherapy : CII 1990;31(3):169-75.
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1989: Tatman J L; Freedman R S; Scott W; Atkinson E N
Treatment of advanced endometrial adenocarcinoma with cyclic sequential ethinyl estradiol and medroxyprogesterone acetate.
European journal of cancer & clinical oncology 1989;25(11):1619-21.
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1989: Ioannides C G; Freedman R S; Platsoucas C D
OKT4 monoclonal antibody-induced activation of an autoreactive T-cell clone.
Cellular immunology 1989;123(1):244-52.
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1989: Freedman R S; Bowen J M; Atkinson E N; Wallace S; Lotzová E; Silva E; Edwards C L; Delclos L; Scott W; Patenia B
Randomized comparison of viral oncolysate plus radiation and radiation alone in uterine cervix carcinoma.
American journal of clinical oncology 1989;12(3):244-50.
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1989: Ioannides C G; Platsoucas C D; O'Brian C A; Patenia R; Bowen J M; Wharton J T; Freedman R S
Viral oncolysates in cancer treatment: immunological mechanisms of action (review).
Anticancer research 1989;9(3):535-44.
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1989: Gershenson D M; Wharton J T; Copeland L J; Stringer C A; Edwards C L; Kavanagh J J; Freedman R S
Treatment of advanced epithelial ovarian cancer with cisplatin and cyclophosphamide.
Gynecologic oncology 1989;32(3):336-41.
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1989: Ioannides C G; Platsoucas C D; Bowen J M; Wharton J T; Freedman R S
Increased ovarian tumor cell surface reacting antibodies in patients with ovarian adenocarcinoma after viral oncolysate treatment.
Anticancer research 1989;9(1):81-6.
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1989: Freedman R S; Kouttab N M; Bowen J M; Edwards C L; Katz R L
Lymphokine activity in malignant effusions after intracavitary viral oncolysate.
Lymphokine research 1989;8(2):115-22.
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1989: Furukawa K; Lotzová E; Freedman R S; Bowen J B; Edwards C L; Wharton J T
Effect of virus-modified tumor cell extracts, autologous mononuclear cell infusions and interleukin-2 on oncolytic activity of effector cells of patients with advanced ovarian cancer.
Cancer immunology, immunotherapy : CII 1989;30(2):126-32.
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1988: Lotzová E; Savary C A; Freedman R S; Edwards C L; Wharton J T
Recombinant IL-2-activated NK cells mediate LAK activity against ovarian cancer.
International journal of cancer. Journal international du cancer 1988;42(2):225-31.
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1988: Kong J S; Peters L J; Wharton J T; Ang K K; Delclos L; Gershenson D M; Copeland L J; Edwards C L; Freedman R S; Saul P B
Hyperfractionated split-course whole abdominal radiotherapy for ovarian carcinoma: tolerance and toxicity.
International journal of radiation oncology, biology, physics 1988;14(4):737-43.
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1988: Freedman R S; Edwards C L; Bowen J M; Lotzova E; Katz R; Lewis E; Atkinson N; Carsetti R
Viral oncolysates in patients with advanced ovarian cancer.
Gynecologic oncology 1988;29(3):337-47.
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