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Eugene Frenkel

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Jonathan W Uhr; Xiaojing J Zhang; Raheela Ashfaq; Lawrence Cheng; Eugene P Frenkel; Michael L Huebschman; Gareth A Hughes; Nancy L Lane; Alice T Lin; Huaying Liu; Dipen R Rana; Harold R Garner
Molecular profiling of individual tumor cells by hyperspectral microscopic imaging.
Sofyan M Radaideh; Ravindra Sarode; Jonathan E Dowell; Eugene P Frenkel; Yu-Min Shen
Incidence of isolated heparin-induced thrombocytopenia and risk of thrombosis by IgG-specific anti-PF4/heparin ELISA.
Jose A Karam; Sandra Huang; Jinhai Fan; Jennifer Stanfield; Roger A Schultz; Rey-Chen Pong; Xiankai Sun; Ralph P Mason; Xian-Jin Xie; Gang Niu; Xiaoyuan Chen; Eugene P Frenkel; Arthur I Sagalowsky; Jer-Tsong Hsieh
Upregulation of TRAG3 gene in urothelial carcinoma of the bladder.

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2012: Jonathan W Uhr; Xiaojing J Zhang; Raheela Ashfaq; Lawrence Cheng; Eugene P Frenkel; Michael L Huebschman; Gareth A Hughes; Nancy L Lane; Alice T Lin; Huaying Liu; Dipen R Rana; Harold R Garner
Molecular profiling of individual tumor cells by hyperspectral microscopic imaging.
Translational research : the journal of laboratory and clinical medicine 2012;159(5):366-75.
2012: Sofyan M Radaideh; Ravindra Sarode; Jonathan E Dowell; Eugene P Frenkel; Yu-Min Shen
Incidence of isolated heparin-induced thrombocytopenia and risk of thrombosis by IgG-specific anti-PF4/heparin ELISA.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2012;18(2):215-7.
2011: Jose A Karam; Sandra Huang; Jinhai Fan; Jennifer Stanfield; Roger A Schultz; Rey-Chen Pong; Xiankai Sun; Ralph P Mason; Xian-Jin Xie; Gang Niu; Xiaoyuan Chen; Eugene P Frenkel; Arthur I Sagalowsky; Jer-Tsong Hsieh
Upregulation of TRAG3 gene in urothelial carcinoma of the bladder.
International journal of cancer. Journal international du cancer 2011;128(12):2823-32.
2009: Wei Zhang; Michael Peyton; Yang Xie; Junichi Soh; John D Minna; Adi F Gazdar; Eugene P Frenkel
Histone deacetylase inhibitor romidepsin enhances anti-tumor effect of erlotinib in non-small cell lung cancer (NSCLC) cell lines.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009;4(2):161-6.
2008: Y M Shen; R Lee; Eugene P Frenkel; Ravindra Sarode
IgA antiphospholipid antibodies are an independent risk factor for thromboses.
Lupus 2008;17(11):996-1003.
2008: Narayan Shivapurkar; Victor Stastny; Naoki Okumura; Luc Girard; Yang Xie; Clemens Prinsen; Frederik B Thunnissen; Ignacio I Wistuba; Bogdan Czerniak; Eugene P Frenkel; Jack A Roth; Triantafillos Liloglou; George Xinarianos; John Field; John D Minna; Adi F Gazdar
Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene.
Cancer research 2008;68(18):7448-56.
2008: Jinhai Fan; Jennifer Stanfield; Yi Guo; Jose A Karam; Eugene P Frenkel; Xiankai Sun; Jer-Tsong Hsieh
Effect of trans-2,3-dimethoxycinnamoyl azide on enhancing antitumor activity of romidepsin on human bladder cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1200-7.
2008: Barbara B Haley; Eugene P Frenkel
Nanoparticles for drug delivery in cancer treatment.
Urologic oncology 2008;26(1):57-64.
2008: Ravindra Sarode; Eugene P Frenkel
And, more on: assessing aspirin responsiveness using the verify now aspirin assay.
Thrombosis research 2008;121(4):587-8.
2007: Anna M Dyszkiewicz-Korpanty; Horatiu Olteanu; Eugene P Frenkel; Ravindra Sarode
Clopidogrel anti-platelet effect: an evaluation by optical aggregometry, impedance aggregometry, and the platelet function analyzer (PFA-100).
Platelets 2007;18(7):491-6.
2007: Zhengwang Zhang; Jennifer Stanfield; Eugene P Frenkel; Wareef Kabbani; Jer-Tsong Hsieh
Enhanced therapeutic effect on androgen-independent prostate cancer by depsipeptide (FK228), a histone deacetylase inhibitor, in combination with docetaxel.
Urology 2007;70(2):396-401.
2007: Yu-Min P Shen; Eugene P Frenkel
Acquired platelet dysfunction.
Hematology/oncology clinics of North America 2007;21(4):647-61, vi.
2007: Jose A Karam; Jinhai Fan; Jennifer Stanfield; Edmond Richer; Elie A Benaim; Eugene P Frenkel; Peter P Antich; Arthur I Sagalowsky; Ralph P Mason; Jer-Tsong Hsieh
The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy.
International journal of cancer. Journal international du cancer 2007;120(8):1795-802.
2007: Anna M Dyszkiewicz-Korpanty; Anne Kim; James D Burner; Eugene P Frenkel; Ravindra Sarode
Comparison of a rapid platelet function assay--Verify Now Aspirin--with whole blood impedance aggregometry for the detection of aspirin resistance.
Thrombosis research 2007;120(4):485-8.
2006: Songdong Meng; Debu Tripathy; Sanjay Shete; Raheela Ashfaq; Hossein Saboorian; Barbara B Haley; Eugene P Frenkel; David M Euhus; Marilyn Leitch; Cynthia Osborne; Edward Clifford; Steve Perkins; Peter D Beitsch; Amanullah Khan; Larry Morrison; Dorothee Herlyn; Leon W M M Terstappen; Nancy Lane; Jianqiang Wang; Jonathan Uhr
uPAR and HER-2 gene status in individual breast cancer cells from blood and tissues.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(46):17361-5.
2006: Makoto Suzuki; Hisayuki Shigematsu; Narayan Shivapurkar; Jyotsna Reddy; Kuniharu Miyajima; Takao Takahashi; Adi F Gazdar; Eugene P Frenkel
Methylation of apoptosis related genes in the pathogenesis and prognosis of prostate cancer.
Cancer letters 2006;242(2):222-30.
2006: Jun Guo; An-wu Zhou; Yu-cai Fu; Udit N Verma; Debu Tripathy; Eugene P Frenkel; Carlos R Becerra
Efficacy of sequential treatment of HCT116 colon cancer monolayers and xenografts with docetaxel, flavopiridol, and 5-fluorouracil.
Acta pharmacologica Sinica 2006;27(10):1375-81.
2006: Rey-Chen Pong; Ryan Roark; Jiun-Yih Ou; Jianhai Fan; Jennifer Stanfield; Eugene P Frenkel; Arthur I Sagalowsky; Jer-Tsong Hsieh
Mechanism of increased coxsackie and adenovirus receptor gene expression and adenovirus uptake by phytoestrogen and histone deacetylase inhibitor in human bladder cancer cells and the potential clinical application.
Cancer research 2006;66(17):8822-8.
2006: Zhengwang Zhang; Jose A Karam; Eugene P Frenkel; Arthur I Sagalowsky; Jer-Tsong Hsieh
The application of epigenetic modifiers on the treatment of prostate and bladder cancer.
Urologic oncology 2006;24(2):152-60.
2006: Ravindra Sarode; Ajay Rawal; Ray Lee; Yu-Min P Shen; Eugene P Frenkel
Poor correlation of supratherapeutic international normalised ratio and vitamin K-dependent procoagulant factor levels during warfarin therapy.
British journal of haematology 2006;132(5):604-7.
2005: Makoto Suzuki; Hisayuki Shigematsu; David Shames; noriaki sunaga; T Takahashi; Narayan Shivapurkar; Toshihiko Iizasa; Eugene P Frenkel; John D Minna; Takehiko Fujisawa; Adi F Gazdar
DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers.
British journal of cancer 2005;93(9):1029-37.
2005: Youn-Tae Kwak; Rui Li; Carlos R Becerra; Debu Tripathy; Eugene P Frenkel; Udit N Verma
IkappaB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylation.
The Journal of biological chemistry 2005;280(40):33945-52.
2005: Eugene P Frenkel; Yu-Min P Shen; Barbara B Haley
The direct thrombin inhibitors: their role and use for rational anticoagulation.
Hematology/oncology clinics of North America 2005;19(1):119-45, vi-vii.
2005: Rodger L Bick; Eugene P Frenkel; Jeanine M Walenga; Jawed Fareed; Debra A Hoppensteadt
Unfractionated heparin, low molecular weight heparins, and pentasaccharide: basic mechanism of actions, pharmacology, and clinical use.
Hematology/oncology clinics of North America 2005;19(1):1-51, v.
2005: Anna M Dyszkiewicz-Korpanty; Eugene P Frenkel; Ravindra Sarode
Approach to the assessment of platelet function: comparison between optical-based platelet-rich plasma and impedance-based whole blood platelet aggregation methods.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2005;11(1):25-35.
2004: Songdong Meng; Debu Tripathy; Eugene P Frenkel; Sanjay Shete; Elizabeth Z Naftalis; James F Huth; Peter D Beitsch; Marilyn Leitch; Susan Hoover; David M Euhus; Barbara B Haley; Larry Morrison; Timothy P Fleming; Dorothee Herlyn; Leon W M M Terstappen; Tanja Fehm; Thomas F Tucker; Nancy Lane; Jianqiang Wang; Jonathan Uhr
Circulating tumor cells in patients with breast cancer dormancy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8152-62.
2004: Suash Sharma; Hossein M Saboorian; William H Frawley; Eugene P Frenkel; Barbara B Haley; Raheela Ashfaq
MIB1 labeling index as an indicator of chemoresponse in carcinoma of the breast.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2004;12(4):290-5.
2004: Yu-Min P Shen; Eugene P Frenkel
Thrombosis and a hypercoagulable state in HIV-infected patients.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2004;10(3):277-80.
2004: Songdong Meng; Debu Tripathy; Sanjay Shete; Raheela Ashfaq; Barbara B Haley; Steve Perkins; Peter D Beitsch; Amanullah Khan; David M Euhus; Cynthia Osborne; Eugene P Frenkel; Susan Hoover; Marilyn Leitch; Edward Clifford; Ellen S Vitetta; Larry Morrison; Dorothee Herlyn; Leon W M M Terstappen; Timothy Fleming; Tanja Fehm; Thomas Tucker; Nancy Lane; Jianqiang Wang; Jonathan Uhr
HER-2 gene amplification can be acquired as breast cancer progresses.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9393-8.
2004: Jun Guo; Udit N Verma; Richard B Gaynor; Eugene P Frenkel; Carlos R Becerra
Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3333-41.
2004: Ubaradka G Sathyanarayana; Riichiroh Maruyama; Asha Padar; Makoto Suzuki; Jolanta Bondaruk; Arthur I Sagalowsky; John D Minna; Eugene P Frenkel; H Barton Grossman; Bogdan Czerniak; Adi F Gazdar
Molecular detection of noninvasive and invasive bladder tumor tissues and exfoliated cells by aberrant promoter methylation of laminin-5 encoding genes.
Cancer research 2004;64(4):1425-30.
2003: Rey-Chen Pong; Yun-Ju Lai; Hong Chen; Takatsugu Okegawa; Eugene P Frenkel; Arthur I Sagalowsky; Jer-Tsong Hsieh
Epigenetic regulation of coxsackie and adenovirus receptor (CAR) gene promoter in urogenital cancer cells.
Cancer research 2003;63(24):8680-6.
2003: Ubaradka G Sathyanarayana; Asha Padar; Makoto Suzuki; Riichiroh Maruyama; Hisayuki Shigematsu; Jer-Tsong Hsieh; Eugene P Frenkel; Adi F Gazdar
Aberrant promoter methylation of laminin-5-encoding genes in prostate cancers and its relationship to clinicopathological features.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(17):6395-400.
2003: Asha Padar; Ubaradka G Sathyanarayana; Makoto Suzuki; Riichiroh Maruyama; Jer-Tsong Hsieh; Eugene P Frenkel; John D Minna; Adi F Gazdar
Inactivation of cyclin D2 gene in prostate cancers by aberrant promoter methylation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):4730-4.
2003: Carlos R Becerra; Eugene P Frenkel; Raheela Ashfaq; Richard B Gaynor
Increased toxicity and lack of efficacy of Rofecoxib in combination with chemotherapy for treatment of metastatic colorectal cancer: A phase II study.
International journal of cancer. Journal international du cancer 2003;105(6):868-72.
2003: Noelle Sevilir Williams; Richard B Gaynor; Shane Scoggin; Udit N Verma; Tunc Gokaslan; Clifford Simmang; Jason Fleming; Denise Tavana; Eugene P Frenkel; Carlos R Becerra
Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):931-46.
2003: Eugene P Frenkel; Eberhard F Mammen
Sticky platelet syndrome and thrombocythemia.
Hematology/oncology clinics of North America 2003;17(1):63-83.
2002: Arthur I Sagalowsky; Eugene P Frenkel
Cobalamin profiles in patients after urinary diversion.
The Journal of urology 2002;167(4):1696-700.
2002: Sijian Wang; M Hossein Saboorian; Eugene P Frenkel; Barbara B Haley; Momin T Siddiqui; S Tunc Gokaslan; Linda Hynan; Raheela Ashfaq
Aneusomy 17 in breast cancer: its role in HER-2/neu protein expression and implication for clinical assessment of HER-2/neu status.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2002;15(2):137-45.
2002: Riichiroh Maruyama; Shinichi Toyooka; Kiyomi O Toyooka; Arvind K Virmani; Sabine Zöchbauer-Müller; Alfredo J Farinas; John D Minna; John McConnell; Eugene P Frenkel; Adi F Gazdar
Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):514-9.
2002: Yingming Li; Takatsugu Okegawa; Donald P Lombardi; Eugene P Frenkel; Jer-Tsong Hsieh
Enhanced transgene expression in androgen independent prostate cancer gene therapy by taxane chemotherapeutic agents.
The Journal of urology 2002;167(1):339-46.
2001: Sijian Wang; M Hossein Saboorian; Eugene P Frenkel; Barbara B Haley; Momin T Siddiqui; S Tunc Gokaslan; Frank H Wians; Linda Hynan; Raheela Ashfaq
Assessment of HER-2/neu status in breast cancer. Automated Cellular Imaging System (ACIS)-assisted quantitation of immunohistochemical assay achieves high accuracy in comparison with fluorescence in situ hybridization assay as the standard.
American journal of clinical pathology 2001;116(4):495-503.
2001: Demetrius M Kokkinakis; R M Hoffman; Eugene P Frenkel; J B Wick; Q Han; M Xu; Y Tan; S Clifford Schold
Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice.
Cancer research 2001;61(10):4017-23.
2001: David I Rosenthal; Jason H Lee; Robert J Sinard; Denise Yardley; Mitchell Machtay; D M Rosen; Merrill J Egorin; Randal S Weber; Gregory S Weinstein; Ara A Chalian; L K Miller; Eugene P Frenkel; David P Carbone
Phase I study of paclitaxel given by seven-week continuous infusion concurrent with radiation therapy for locally advanced squamous cell carcinoma of the head and neck.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(5):1363-73.
2000: David I Rosenthal; Carlos R Becerra; R D Toto; David P Carbone; Eugene P Frenkel
Reversible renal toxicity resulting from high single doses of the new radiosensitizer gadolinium texaphyrin.
American journal of clinical oncology 2000;23(6):593-8.
2000: M Y Hamdan; Eugene P Frenkel; R Bick
L-asparaginase-provoked seizures as singular expression of central nervous toxicity.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2000;6(4):234-8.
2000: Eugene P Frenkel; Denise Yardley
Clinical and laboratory features and sequelae of deficiency of folic acid (folate) and vitamin B12 (cobalamin) in pregnancy and gynecology.
Hematology/oncology clinics of North America 2000;14(5):1079-100, viii.
2000: S Wang; M Hossein Saboorian; Eugene P Frenkel; Linda Hynan; S Tunc Gokaslan; Raheela Ashfaq
Laboratory assessment of the status of Her-2/neu protein and oncogene in breast cancer specimens: comparison of immunohistochemistry assay with fluorescence in situ hybridisation assays.
Journal of clinical pathology 2000;53(5):374-81.
1999: Rodger L Bick; Eugene P Frenkel
Clinical aspects of heparin-induced thrombocytopenia and thrombosis and other side effects of heparin therapy.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 1999;5 Suppl 1():S7-15.
1999: David I Rosenthal; P Nurenberg; Carlos R Becerra; Eugene P Frenkel; David P Carbone; B L Lum; R Miller; J Engel; S Young; D Miles; Markus F Renschler
A phase I single-dose trial of gadolinium texaphyrin (Gd-Tex), a tumor selective radiation sensitizer detectable by magnetic resonance imaging.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(4):739-45.
1999: Eugene P Frenkel; Rodger L Bick
Prothrombin G20210A gene mutation, heparin cofactor II defects, primary (essential) thrombocythemia, and thrombohemorrhagic manifestations.
Seminars in thrombosis and hemostasis 1999;25(4):375-86.
1998: Eugene P Frenkel; R Bick
Issues of thrombosis and hemorrhagic events in patients with cancer.
In vivo (Athens, Greece) 1998;12(6):625-8.
1997: R S Hughes; Eugene P Frenkel
The role of chemotherapy in head and neck cancer.
American journal of clinical oncology 1997;20(5):449-61.