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Jean-Marie Frère
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68
Galleni, Moreno
56
Joris, Bernard
32
Ghuysen, Jean-Marie
29
Lamotte-Brasseur, Josette
28
Dideberg, Otto
26
Amicosante, Gianfranco
25
Rossolini, Gian Maria
24
Matagne, Alain
23
Charlier, Paulette
21
Van Beeumen, Jozef
18
Devreese, Bart
18
Duez, Colette
15
Dusart, Jean
15
Dubus, Alain
14
Vanhove, Marc
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All Publications
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2009: Duez Colette; Zervosen Astrid; Teller Nathalie; Melkonian Rémy; Banzubazé Emmanuel; Bouillenne Fabrice; Luxen André; Frère Jean-Marie
Characterization of the proteins encoded by the Bacillus subtilis yoxA-dacC operon.
FEMS microbiology letters 2009;300(1):42-7.
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2009: Decrem Yves; Rath Géraldine; Blasioli Virginie; Cauchie Philippe; Robert Séverine; Beaufays Jérôme; Frère Jean-Marie; Feron Olivier; Dogné Jean-Michel; Dessy Chantal; Vanhamme Luc; Godfroid Edmond
Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis.
The Journal of experimental medicine 2009;206(11):2381-95.
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2009: Jacquin Olivier; Balbeur Dorothée; Damblon Christian; Marchot Pierre; De Pauw Edwin; Roberts Gordon C K; Frère Jean-Marie; Matagne André
Positively cooperative binding of zinc ions to Bacillus cereus 569/H/9 beta-lactamase II suggests that the binuclear enzyme is the only relevant form for catalysis.
Journal of molecular biology 2009;392(5):1278-91.
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2009: Zeba Boukaré; De Luca Filomena; Dubus Alain; Delmarcelle Michael; Simporé Jacques; Nacoulma Odile G; Rossolini Gian Maria; Frère Jean-Marie; Docquier Jean-Denis
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso.
Antimicrobial agents and chemotherapy 2009;53(10):4320-6.
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2009: Bebrone Carine; Delbrück Heinrich; Kupper Michaël B; Schlömer Philipp; Willmann Charlotte; Frère Jean-Marie; Fischer Rainer; Galleni Moreno; Hoffmann Kurt M V
The structure of the dizinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the histidine site.
Antimicrobial agents and chemotherapy 2009;53(10):4464-71.
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2008: Dumez Marie-Eve; Teller Nathalie; Mercier Frédéric; Tanaka Tetsuya; Vandenberghe Isabel; Vandenbranden Michel; Devreese Bart; Luxen André; Frère Jean-Marie; Matagne André; Jacquet Alain; Galleni Moreno; Chevigné Andy
Activation mechanism of recombinant Der p 3 allergen zymogen: contribution of cysteine protease Der p 1 and effect of propeptide glycosylation.
The Journal of biological chemistry 2008;283(45):30606-17.
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2008: Ruth Nadia; Quinting Birgit; Mainil Jacques; Hallet Bernard; Frère Jean-Marie; Huygen Kris; Galleni Moreno
Creating hybrid proteins by insertion of exogenous peptides into permissive sites of a class A beta-lactamase.
The FEBS journal 2008;275(20):5150-60.
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2008: Bebrone Carine; Anne Christine; Kerff Frédéric; Garau Gianpiero; De Vriendt Kris; Lantin Raphaël; Devreese Bart; Van Beeumen Jozef; Dideberg Otto; Frère Jean-Marie; Galleni Moreno
Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila.
The Biochemical journal 2008;414(1):151-9.
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2008: Liénard Benoît M R; Garau Gianpiero; Horsfall Louise; Karsisiotis Andreas I; Damblon Christian; Lassaux Patricia; Papamicael Cyril; Roberts Gordon C K; Galleni Moreno; Dideberg Otto; Frère Jean-Marie; Schofield Christopher J
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.
Organic & biomolecular chemistry 2008;6(13):2282-94.
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2008: Vandevenne M; Gaspard G; Yilmaz N; Giannotta F; Frère J M; Galleni M; Filée P
Rapid and easy development of versatile tools to study protein/ligand interactions.
Protein engineering, design & selection : PEDS 2008;21(7):443-51.
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2008: Stoczko Magdalena; Frère Jean-Marie; Rossolini Gian Maria; Docquier Jean-Denis
Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora.
Antimicrobial agents and chemotherapy 2008;52(7):2473-9.
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2008: Michaux Catherine; Massant Jan; Kerff Frédéric; Frère Jean-Marie; Docquier Jean-Denis; Vandenberghe Isabel; Samyn Bart; Pierrard Annick; Feller Georges; Charlier Paulette; Van Beeumen Jozef; Wouters Johan
Crystal structure of a cold-adapted class C beta-lactamase.
The FEBS journal 2008;275(8):1687-97.
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2008: Liénard Benoît M R; Hüting Rebekka; Lassaux Patricia; Galleni Moreno; Frère Jean-Marie; Schofield Christopher J
Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors.
Journal of medicinal chemistry 2008;51(3):684-8.
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2008: Lejeune Annabelle; Pain Roger H; Charlier Paulette; Frère Jean-Marie; Matagne André
TEM-1 beta-lactamase folds in a nonhierarchical manner with transient non-native interactions involving the C-terminal region.
Biochemistry 2008;47(4):1186-93.
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2007: Chevigné Andy; Barumandzadeh Roya; Groslambert Sylvie; Cloes Benoît; Dehareng Dominique; Filée Patrice; Marx Jean-Claude; Frère Jean-Marie; Matagne André; Jacquet Alain; Galleni Moreno
Relationship between propeptide pH unfolding and inhibitory ability during ProDer p 1 activation mechanism.
Journal of molecular biology 2007;374(1):170-85.
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2007: Vandevenne Marylène; Filee Patrice; Scarafone Natacha; Cloes Benoît; Gaspard Gilles; Yilmaz Nursel; Dumoulin Mireille; François Jean-Marie; Frère Jean-Marie; Galleni Moreno
The Bacillus licheniformis BlaP beta-lactamase as a model protein scaffold to study the insertion of protein fragments.
Protein science : a publication of the Protein Society 2007;16(10):2260-71.
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2007: Sauvage Eric; Duez Colette; Herman Raphaël; Kerff Frédéric; Petrella Stephanie; Anderson John W; Adediran S A; Pratt R F; Frère Jean-Marie; Charlier Paulette
Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide.
Journal of molecular biology 2007;371(2):528-39.
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2007: Horsfall L E; Garau G; Liénard B M R; Dideberg O; Schofield C J; Frère J M; Galleni M
Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila.
Antimicrobial agents and chemotherapy 2007;51(6):2136-42.
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2007: Chevigné Andy; Yilmaz Nursel; Gaspard Gilles; Giannotta Fabrizio; François Jean Marie; Frère Jean Marie; Galleni Moreno; Filée Patrice
Use of bifunctional hybrid beta-lactamases for epitope mapping and immunoassay development.
Journal of immunological methods 2007;320(1-2):81-93.
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2007: Ishii Yoshikazu; Galleni Moreno; Ma Ling; Frère Jean-Marie; Yamaguchi Keizo
Biochemical characterisation of the CTX-M-14 beta-lactamase.
International journal of antimicrobial agents 2007;29(2):159-64.
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2007: Liénard Benoît M R; Horsfall Louise E; Galleni Moreno; Frère Jean-Marie; Schofield Christopher J
Inhibitors of the FEZ-1 metallo-beta-lactamase.
Bioorganic & medicinal chemistry letters 2007;17(4):964-8.
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2006: Sauvage Eric; Fonzé Eveline; Quinting Birgit; Galleni Moreno; Frère Jean-Marie; Charlier Paulette
Crystal structure of the Mycobacterium fortuitum class A beta-lactamase: structural basis for broad substrate specificity.
Antimicrobial agents and chemotherapy 2006;50(7):2516-21.
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2006: Selevsek Nathalie; Tholey Andreas; Heinzle Elmar; Liénard Benoît M R; Oldham Neil J; Schofield Christopher J; Heinz Uwe; Adolph Hans-Werner; Frère Jean-Marie
Studies on ternary metallo-beta lactamase-inhibitor complexes using electrospray ionization mass spectrometry.
Journal of the American Society for Mass Spectrometry 2006;17(7):1000-4.
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2006: Stoczko Magdalena; Frère Jean-Marie; Rossolini Gian Maria; Docquier Jean-Denis
Postgenomic scan of metallo-beta-lactamase homologues in rhizobacteria: identification and characterization of BJP-1, a subclass B3 ortholog from Bradyrhizobium japonicum.
Antimicrobial agents and chemotherapy 2006;50(6):1973-81.
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2006: Fraipont Claudine; Sapunaric Frédéric; Zervosen Astrid; Auger Geneviève; Devreese Bart; Lioux Thierry; Blanot Didier; Mengin-Lecreulx Dominique; Herdewijn Piet; Van Beeumen Jozef; Frère Jean-Marie; Nguyen-Distèche Martine
Glycosyl transferase activity of the Escherichia coli penicillin-binding protein 1b: specificity profile for the substrate.
Biochemistry 2006;45(12):4007-13.
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2006: Zawadzka-Skomial Joanna; Markiewicz Zdzislaw; Nguyen-Distèche Martine; Devreese Bart; Frère Jean-Marie; Terrak Mohammed
Characterization of the bifunctional glycosyltransferase/acyltransferase penicillin-binding protein 4 of Listeria monocytogenes.
Journal of bacteriology 2006;188(5):1875-81.
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2006: De Vriendt Kris; Van Driessche Gonzalez; Devreese Bart; Bebrone Carine; Anne Christine; Frère Jean-Marie; Galleni Moreno; Van Beeumen Jozef
Monitoring the zinc affinity of the metallo-beta-lactamase CphA by automated nanoESI-MS.
Journal of the American Society for Mass Spectrometry 2006;17(2):180-8.
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2005: Rhazi Noureddine; Delmarcelle Michael; Sauvage Eric; Jacquemotte Françoise; Devriendt Kris; Tallon Valérie; Ghosez Léon; Frère Jean-Marie
Specificity and reversibility of the transpeptidation reaction catalyzed by the Streptomyces R61 D-Ala-D-Ala peptidase.
Protein science : a publication of the Protein Society 2005;14(11):2922-8.
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2005: Frère Jean-Marie; Marchot Pierre
Inactivators in competition. How to deal with them ... and not!
Biochemical pharmacology 2005;70(10):1417-23.
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2005: Adediran S A; Nukaga Michiyoshi; Baurin Stéphane; Frère J-M; Pratt R F
Inhibition of class D beta-lactamases by acyl phosphates and phosphonates.
Antimicrobial agents and chemotherapy 2005;49(10):4410-2.
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2005: Bauvois Cédric; Ibuka Akiko Shimizu; Celso Almeida; Alba Jimena; Ishii Yoshikazu; Frère Jean-Marie; Galleni Moreno
Kinetic properties of four plasmid-mediated AmpC beta-lactamases.
Antimicrobial agents and chemotherapy 2005;49(10):4240-6.
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2005: Delmarcelle Michaël; Boursoit Marie-Caroline; Filée Patrice; Baurin Stéphane Lucius; Frère Jean-Marie; Joris Bernard
Specificity inversion of Ochrobactrum anthropi D-aminopeptidase to a D,D-carboxypeptidase with new penicillin binding activity by directed mutagenesis.
Protein science : a publication of the Protein Society 2005;14(9):2296-303.
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2005: Sauvage Eric; Herman Raphaël; Petrella Stephanie; Duez Colette; Bouillenne Fabrice; Frère Jean-Marie; Charlier Paulette
Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins.
The Journal of biological chemistry 2005;280(35):31249-56.
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2005: Bebrone Carine; Anne Christine; De Vriendt Kris; Devreese Bart; Rossolini Gian Maria; Van Beeumen Jozef; Frère Jean-Marie; Galleni Moreno
Dramatic broadening of the substrate profile of the Aeromonas hydrophila CphA metallo-beta-lactamase by site-directed mutagenesis.
The Journal of biological chemistry 2005;280(31):28195-202.
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2005: Llinás Antonio; Ahmed Naveed; Cordaro Massimiliano; Laws Andrew P; Frère Jean-Marie; Delmarcelle Michael; Silvaggi Nicholas R; Kelly Judith A; Page Michael I
Inactivation of bacterial DD-peptidase by beta-sultams.
Biochemistry 2005;44(21):7738-46.
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2005: Ruth Nadia; Mainil Jacques; Roupie Virginie; Frère Jean-Marie; Galleni Moreno; Huygen Kris
DNA vaccination for the priming of neutralizing antibodies against non-immunogenic STa enterotoxin from enterotoxigenic Escherichia coli.
Vaccine 2005;23(27):3618-27.
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2005: De Lemos Esteves Frédéric; Gouders Thierry; Lamotte-Brasseur Josette; Rigali Sébastien; Frère Jean-Marie
Improving the alkalophilic performances of the Xyl1 xylanase from Streptomyces sp. S38: structural comparison and mutational analysis.
Protein science : a publication of the Protein Society 2005;14(2):292-302.
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2005: Garau Gianpiero; Bebrone Carine; Anne Christine; Galleni Moreno; Frère Jean-Marie; Dideberg Otto
A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem.
Journal of molecular biology 2005;345(4):785-95.
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2004: Docquier Jean-Denis; Lopizzo Teresa; Liberatori Sabrina; Prenna Manuela; Thaller Maria Cristina; Frère Jean-Marie; Rossolini Gian Maria
Biochemical characterization of the THIN-B metallo-beta-lactamase of Janthinobacterium lividum.
Antimicrobial agents and chemotherapy 2004;48(12):4778-83.
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2004: Vreuls Christelle; Filée Patrice; Van Melckebeke Hélène; Aerts Tony; De Deyn Peter; Llabrès Gabriel; Matagne André; Simorre Jean-Pierre; Frère Jean-Marie; Joris Bernard
Guanidinium chloride denaturation of the dimeric Bacillus licheniformis BlaI repressor highlights an independent domain unfolding pathway.
The Biochemical journal 2004;384(Pt 1):179-90.
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2004: Dreesen L; Humbert C; Sartenaer Y; Caudano Y; Volcke C; Mani A A; Peremans A; Thiry P A; Hanique S; Frère J-M
Electronic and molecular properties of an adsorbed protein monolayer probed by two-color sum-frequency generation spectroscopy.
Langmuir : the ACS journal of surfaces and colloids 2004;20(17):7201-7.
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2004: Mercuri Paola Sandra; García-Sáez Isabel; De Vriendt Kris; Thamm Iris; Devreese Bart; Van Beeumen Jozef; Dideberg Otto; Rossolini Gian Maria; Frère Jean-Marie; Galleni Moreno
Probing the specificity of the subclass B3 FEZ-1 metallo-beta-lactamase by site-directed mutagenesis.
The Journal of biological chemistry 2004;279(32):33630-8.
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2004: Garau Gianpiero; García-Sáez Isabel; Bebrone Carine; Anne Christine; Mercuri Paola; Galleni Moreno; Frère Jean-Marie; Dideberg Otto
Update of the standard numbering scheme for class B beta-lactamases.
Antimicrobial agents and chemotherapy 2004;48(7):2347-9.
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2004: de Lemos Esteves Frédéric; Ruelle Virginie; Lamotte-Brasseur Josette; Quinting Birgit; Frère Jean-Marie
Acidophilic adaptation of family 11 endo-beta-1,4-xylanases: modeling and mutational analysis.
Protein science : a publication of the Protein Society 2004;13(5):1209-18.
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2004: Tsang Wing Y; Dhanda Anupma; Schofield Christopher J; Frère Jean-Marie; Galleni Moreno; Page Michael I
The inhibition of metallo-beta-lactamase by thioxo-cephalosporin derivatives.
Bioorganic & medicinal chemistry letters 2004;14(7):1737-9.
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2004: Hanique Sophie; Colombo Maria-Luigi; Goormaghtigh Erik; Soumillion Patrice; Frère Jean-Marie; Joris Bernard
Evidence of an intramolecular interaction between the two domains of the BlaR1 penicillin receptor during the signal transduction.
The Journal of biological chemistry 2004;279(14):14264-72.
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2004: Zervosen Astrid; Lu Wei-Ping; Chen Zhouliang; White Ronald E; Demuth Thomas P; Frère Jean-Marie
Interactions between penicillin-binding proteins (PBPs) and two novel classes of PBP inhibitors, arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-ones.
Antimicrobial agents and chemotherapy 2004;48(3):961-9.
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2004: Grisart Bernard; Farnir Frédéric; Karim Latifa; Cambisano Nadine; Kim Jong-Joo; Kvasz Alex; Mni Myriam; Simon Patricia; Frère Jean-Marie; Coppieters Wouter; Georges Michel
Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2398-403.
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2004: Colombo Maria-Luigi; Hanique Sophie; Baurin Stéphane L; Bauvois Cédric; De Vriendt Kris; Van Beeumen Jozef J; Frère Jean-Marie; Joris Bernard
The ybxI gene of Bacillus subtilis 168 encodes a class D beta-lactamase of low activity.
Antimicrobial agents and chemotherapy 2004;48(2):484-90.
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2004: Généreux Catherine; Dehareng Dominique; Devreese Bart; Van Beeumen Jozef; Frère Jean-Marie; Joris Bernard
Mutational analysis of the catalytic centre of the Citrobacter freundii AmpD N-acetylmuramyl-L-alanine amidase.
The Biochemical journal 2004;377(Pt 1):111-20.
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2003: Vanhove M; Zakhem M; Devreese B; Franceschini N; Anne C; Bebrone C; Amicosante G; Rossolini G M; Van Beeumen J; Frère J M; Galleni M
Role of Cys221 and Asn116 in the zinc-binding sites of the Aeromonas hydrophila metallo-beta-lactamase.
Cellular and molecular life sciences : CMLS 2003;60(11):2501-9.
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2003: Kerff Frédéric; Charlier Paulette; Colombo Maria-Luigi; Sauvage Eric; Brans Alain; Frère Jean-Marie; Joris Bernard; Fonzé Eveline
Crystal structure of the sensor domain of the BlaR penicillin receptor from Bacillus licheniformis.
Biochemistry 2003;42(44):12835-43.
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2003: Ibuka Akiko Shimizu; Ishii Yoshikazu; Galleni Moreno; Ishiguro Masaji; Yamaguchi Keizo; Frère Jean-Marie; Matsuzawa Hiroshi; Sakai Hiroshi
Crystal structure of extended-spectrum beta-lactamase Toho-1: insights into the molecular mechanism for catalytic reaction and substrate specificity expansion.
Biochemistry 2003;42(36):10634-43.
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2003: Wouters J; Fonzé E; Vermeire M; Frère J-M; Charlier P
Crystal structure of Enterobacter cloacae 908R class C beta-lactamase bound to iodo-acetamido-phenyl boronic acid, a transition-state analogue.
Cellular and molecular life sciences : CMLS 2003;60(8):1764-73.
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2003: Anderson John W; Adediran Suara A; Charlier Paulette; Nguyen-Distèche Martine; Frère Jean-Marie; Nicholas Robert A; Pratt Rex F
On the substrate specificity of bacterial DD-peptidases: evidence from two series of peptidoglycan-mimetic peptides.
The Biochemical journal 2003;373(Pt 3):949-55.
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2003: Duval Valérie; Swinnen Marc; Lepage Sophie; Brans Alain; Granier Benoît; Franssen Christine; Frère Jean-Marie; Joris Bernard
The kinetic properties of the carboxy terminal domain of the Bacillus licheniformis 749/I BlaR penicillin-receptor shed a new light on the derepression of beta-lactamase synthesis.
Molecular microbiology 2003;48(6):1553-64.
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2003: García-Saez Isabel; Hopkins Julie; Papamicael Cyril; Franceschini Nicola; Amicosante Gianfranco; Rossolini Gian Maria; Galleni Moreno; Frère Jean-Marie; Dideberg Otto
The 1.5-A structure of Chryseobacterium meningosepticum zinc beta-lactamase in complex with the inhibitor, D-captopril.
The Journal of biological chemistry 2003;278(26):23868-73.
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2003: Filée Patrice; Vreuls Christelle; Herman Raphaël; Thamm Iris; Aerts Tony; De Deyn Peter P; Frère Jean-Marie; Joris Bernard
Dimerization and DNA binding properties of the Bacillus licheniformis 749/I BlaI repressor.
The Journal of biological chemistry 2003;278(19):16482-7.
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2003: Moali Catherine; Anne Christine; Lamotte-Brasseur Josette; Groslambert Sylvie; Devreese Bart; Van Beeumen Jozef; Galleni Moreno; Frère Jean Marie
Analysis of the importance of the metallo-beta-lactamase active site loop in substrate binding and catalysis.
Chemistry & biology 2003;10(4):319-29.
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2003: Rhazi Noureddine; Charlier Paulette; Dehareng Dominique; Engher Danièle; Vermeire Marcel; Frère Jean-Marie; Nguyen-Distèche Martine; Fonzé Eveline
Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis.
Biochemistry 2003;42(10):2895-906.
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2003: Docquier Jean-Denis; Lamotte-Brasseur Josette; Galleni Moreno; Amicosante Gianfranco; Frère Jean-Marie; Rossolini Gian Maria
On functional and structural heterogeneity of VIM-type metallo-beta-lactamases.
The Journal of antimicrobial chemotherapy 2003;51(2):257-66.
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2003: García-Sáez I; Mercuri P S; Papamicael C; Kahn R; Frère J M; Galleni M; Rossolini G M; Dideberg O
Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril.
Journal of molecular biology 2003;325(4):651-60.
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2002: Lakaye Bernard; Dubus Alain; Joris Bernard; Frère Jean-Marie
Method for estimation of low outer membrane permeability to beta-lactam antibiotics.
Antimicrobial agents and chemotherapy 2002;46(9):2901-7.
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2002: Docquier Jean-Denis; Pantanella Fabrizio; Giuliani Francesco; Thaller Maria Cristina; Amicosante Gianfranco; Galleni Moreno; Frère Jean-Marie; Bush Karen; Rossolini Gian Maria
CAU-1, a subclass B3 metallo-beta-lactamase of low substrate affinity encoded by an ortholog present in the Caulobacter crescentus chromosome.
Antimicrobial agents and chemotherapy 2002;46(6):1823-30.
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2002: Filée Patrice; Benlafya Kamal; Delmarcelle Michaël; Moutzourelis Georgios; Frère Jean-Marie; Brans Alain; Joris Bernard
The fate of the BlaI repressor during the induction of the Bacillus licheniformis BlaP beta-lactamase.
Molecular microbiology 2002;44(3):685-94.
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2002: de Seny Dominique; Prosperi-Meys Christelle; Bebrone Carine; Rossolini Gian Maria; Page Michael I; Noel Philippe; Frère Jean-Marie; Galleni Moreno
Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-beta-lactamase.
The Biochemical journal 2002;363(Pt 3):687-96.
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2002: Fonzé Eveline; Vanhove Marc; Dive Georges; Sauvage Eric; Frère Jean-Marie; Charlier Paulette
Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin.
Biochemistry 2002;41(6):1877-85.
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2001: Franceschini N; Boschi L; Pollini S; Herman R; Perilli M; Galleni M; Frère J M; Amicosante G; Rossolini G M
Characterization of OXA-29 from Legionella (Fluoribacter) gormanii: molecular class D beta-lactamase with unusual properties.
Antimicrobial agents and chemotherapy 2001;45(12):3509-16.
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2001: Conrath K E; Lauwereys M; Galleni M; Matagne A; Frère J M; Kinne J; Wyns L; Muyldermans S
Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae.
Antimicrobial agents and chemotherapy 2001;45(10):2807-12.
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2001: Lejeune A; Vanhove M; Lamotte-Brasseur J; Pain R H; Frère J M; Matagne A
Quantitative analysis of the stabilization by substrate of Staphylococcus aureus PC1 beta-lactamase.
Chemistry & biology 2001;8(8):831-42.
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2001: Remaut H; Bompard-Gilles C; Goffin C; Frère J M; Van Beeumen J
Structure of the Bacillus subtilis D-aminopeptidase DppA reveals a novel self-compartmentalizing protease.
Nature structural biology 2001;8(8):674-8.
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2001: Vilar M; Galleni M; Solmajer T; Turk B; Frère J M; Matagne A
Kinetic study of two novel enantiomeric tricyclic beta-lactams which efficiently inactivate class C beta-lactamases.
Antimicrobial agents and chemotherapy 2001;45(8):2215-23.
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2001: Zervosen A; Valladares M H; Devreese B; Prosperi-Meys C; Adolph H W; Mercuri P S; Vanhove M; Amicosante G; van Beeumen J; Frère J M; Galleni M
Inactivation of Aeromonas hydrophila metallo-beta-lactamase by cephamycins and moxalactam.
European journal of biochemistry / FEBS 2001;268(13):3840-50.
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2001: Bebrone C; Moali C; Mahy F; Rival S; Docquier J D; Rossolini G M; Fastrez J; Pratt R F; Frère J M; Galleni M
CENTA as a chromogenic substrate for studying beta-lactamases.
Antimicrobial agents and chemotherapy 2001;45(6):1868-71.
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2001: Mercuri P S; Bouillenne F; Boschi L; Lamotte-Brasseur J; Amicosante G; Devreese B; van Beeumen J; Frère J M; Rossolini G M; Galleni M
Biochemical characterization of the FEZ-1 metallo-beta-lactamase of Legionella gormanii ATCC 33297T produced in Escherichia coli.
Antimicrobial agents and chemotherapy 2001;45(4):1254-62.
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2001: Galleni M; Lamotte-Brasseur J; Rossolini G M; Spencer J; Dideberg O; Frère J M;
Standard numbering scheme for class B beta-lactamases.
Antimicrobial agents and chemotherapy 2001;45(3):660-3.
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2001: Duez C; Vanhove M; Gallet X; Bouillenne F; Docquier J; Brans A; Frère J
Purification and characterization of PBP4a, a new low-molecular-weight penicillin-binding protein from Bacillus subtilis.
Journal of bacteriology 2001;183(5):1595-9.
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2001: Wouters J; Charlier P; Monnaie D; Frère J M; Fonzé E
Expression, purification, crystallization and preliminary X-ray analysis of the native class C beta-lactamase from Enterobacter cloacae 908R and two mutants.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 1):162-4.
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2000: Dubus A; Sami M; Brown T J; Schofield C J; Baldwin J E; Frère J M
Studies of isopenicillin N synthase enzymatic properties using a continuous spectrophotometric assay.
FEBS letters 2000;485(2-3):142-6.
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2000: Cheggour A; Fanuel L; Duez C; Joris B; Bouillenne F; Devreese B; Van Driessche G; Van Beeumen J; Frère J M; Goffin C
The dppA gene of Bacillus subtilis encodes a new D-aminopeptidase.
Molecular microbiology 2000;38(3):504-13.
-
2000: Franceschini N; Caravelli B; Docquier J D; Galleni M; Frère J M; Amicosante G; Rossolini G M
Purification and biochemical characterization of the VIM-1 metallo-beta-lactamase.
Antimicrobial agents and chemotherapy 2000;44(11):3003-7.
-
2000: Bompard-Gilles C; Remaut H; Villeret V; Prangé T; Fanuel L; Delmarcelle M; Joris B; Frère J; Van Beeumen J
Crystal structure of a D-aminopeptidase from Ochrobactrum anthropi, a new member of the 'penicillin-recognizing enzyme' family.
Structure (London, England : 1993) 2000;8(9):971-80.
-
2000: Chantalat L; Duée E; Galleni M; Frère J M; Dideberg O
Structural effects of the active site mutation cysteine to serine in Bacillus cereus zinc-beta-lactamase.
Protein science : a publication of the Protein Society 2000;9(7):1402-6.
-
2000: Boschi L; Mercuri P S; Riccio M L; Amicosante G; Galleni M; Frère J M; Rossolini G M
The Legionella (Fluoribacter) gormanii metallo-beta-lactamase: a new member of the highly divergent lineage of molecular-subclass B3 beta-lactamases.
Antimicrobial agents and chemotherapy 2000;44(6):1538-43.
-
2000: Georis J; de Lemos Esteves F; Lamotte-Brasseur J; Bougnet V; Devreese B; Giannotta F; Granier B; Frère J M
An additional aromatic interaction improves the thermostability and thermophilicity of a mesophilic family 11 xylanase: structural basis and molecular study.
Protein science : a publication of the Protein Society 2000;9(3):466-75.
-
2000: Hernandez Valladares M; Kiefer M; Heinz U; Soto R P; Meyer-Klaucke W; Nolting H F; Zeppezauer M; Galleni M; Frère J M; Rossolini G M; Amicosante G; Adolph H W
Kinetic and spectroscopic characterization of native and metal-substituted beta-lactamase from Aeromonas hydrophila AE036.
FEBS letters 2000;467(2-3):221-5.
-
2000: Bompard-Gilles C; Villeret V; Davies G J; Fanuel L; Joris B; Frère J M; Van Beeumen J
A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi.
Structure (London, England : 1993) 2000;8(2):153-62.
-
2000: Bouillenne F; Matagne A; Joris B; Frère J M
Technique for a rapid and efficient purification of the SHV-1 and PSE-2 beta-lactamases.
Journal of chromatography. B, Biomedical sciences and applications 2000;737(1-2):261-5.
-
1999: Georis J; Giannotta F; Lamotte-Brasseur J; Devreese B; Van Beeumen J; Granier B; Frère J M
Sequence, overproduction and purification of the family 11 endo-beta-1,4-xylanase encoded by the xyl1 gene of Streptomyces sp. S38.
Gene 1999;237(1):123-33.
-
1999: Rossolini G M; Franceschini N; Lauretti L; Caravelli B; Riccio M L; Galleni M; Frère J M; Amicosante G
Cloning of a Chryseobacterium (Flavobacterium) meningosepticum chromosomal gene (blaA(CME)) encoding an extended-spectrum class A beta-lactamase related to the Bacteroides cephalosporinases and the VEB-1 and PER beta-lactamases.
Antimicrobial agents and chemotherapy 1999;43(9):2193-9.
-
1999: Rhazi N; Galleni M; Page M I; Frère J M
Peptidase activity of beta-lactamases.
The Biochemical journal 1999;341 ( Pt 2)():409-13.
-
1999: Fanuel L; Goffin C; Cheggour A; Devreese B; Van Driessche G; Joris B; Van Beeumen J; Frère J M
The DmpA aminopeptidase from Ochrobactrum anthropi LMG7991 is the prototype of a new terminal nucleophile hydrolase family.
The Biochemical journal 1999;341 ( Pt 1)():147-55.
-
1999: Fanuel L; Thamm I; Kostanjevecki V; Samyn B; Joris B; Goffin C; Brannigan J; Van Beeumen J; Frère J M
Two new aminopeptidases from Ochrobactrum anthropi active on D-alanyl-p-nitroanilide.
Cellular and molecular life sciences : CMLS 1999;55(5):812-8.
-
1999: Paul-Soto R; Bauer R; Frère J M; Galleni M; Meyer-Klaucke W; Nolting H; Rossolini G M; de Seny D; Hernandez-Valladares M; Zeppezauer M; Adolph H W
Mono- and binuclear Zn2+-beta-lactamase. Role of the conserved cysteine in the catalytic mechanism.
The Journal of biological chemistry 1999;274(19):13242-9.
-
1999: Laraki N; Franceschini N; Rossolini G M; Santucci P; Meunier C; de Pauw E; Amicosante G; Frère J M; Galleni M
Biochemical characterization of the Pseudomonas aeruginosa 101/1477 metallo-beta-lactamase IMP-1 produced by Escherichia coli.
Antimicrobial agents and chemotherapy 1999;43(4):902-6.
-
1999: Laraki N; Galleni M; Thamm I; Riccio M L; Amicosante G; Frère J M; Rossolini G M
Structure of In31, a blaIMP-containing Pseudomonas aeruginosa integron phyletically related to In5, which carries an unusual array of gene cassettes.
Antimicrobial agents and chemotherapy 1999;43(4):890-901.
-
1999: Bompard-Gilles C; Villeret V; Fanuel L; Joris B; Frère J M; Van Beeumen J
Crystallization and preliminary X-ray analysis of a new L-aminopeptidase-D-amidase/D-esterase activated by a Gly-Ser peptide bond hydrolysis.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 3):699-701.
-
1999: Matagne A; Dubus A; Galleni M; Frère J M
The beta-lactamase cycle: a tale of selective pressure and bacterial ingenuity.
Natural product reports 1999;16(1):1-19.
-
1999: Frère J M; Dubus A; Galleni M; Matagne A; Amicosante G
Mechanistic diversity of beta-lactamases.
Biochemical Society transactions 1999;27(2):58-63.
-
1999: Lakaye B; Dubus A; Lepage S; Groslambert S; Frère J M
When drug inactivation renders the target irrelevant to antibiotic resistance: a case story with beta-lactams.
Molecular microbiology 1999;31(1):89-101.
-
1998: Paul-Soto R; Hernandez-Valladares M; Galleni M; Bauer R; Zeppezauer M; Frère J M; Adolph H W
Mono- and binuclear Zn-beta-lactamase from Bacteroides fragilis: catalytic and structural roles of the zinc ions.
FEBS letters 1998;438(1-2):137-40.
-
1998: Wilkin J M; Lamotte-Brasseur J; Frère J M
The catalytic mechanism of DD-peptidases: unexpected importance of tyrosine 280 in the transpeptidation reaction catalysed by the Streptomyces R61 DD-peptidase.
Cellular and molecular life sciences : CMLS 1998;54(7):726-32.
-
1998: Carfi A; Duée E; Galleni M; Frère J M; Dideberg O
1.85 A resolution structure of the zinc (II) beta-lactamase from Bacillus cereus.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 3):313-23.
-
1998: Matagne A; Lamotte-Brasseur J; Frère J M
Catalytic properties of class A beta-lactamases: efficiency and diversity.
The Biochemical journal 1998;330 ( Pt 2)():581-98.
-
1998: Vanhove M; Lejeune A; Guillaume G; Virden R; Pain R H; Schmid F X; Frère J M
A collapsed intermediate with nonnative packing of hydrophobic residues in the folding of TEM-1 beta-lactamase.
Biochemistry 1998;37(7):1941-50.
-
1998: Carfi A; Duée E; Paul-Soto R; Galleni M; Frère J M; Dideberg O
X-ray structure of the ZnII beta-lactamase from Bacteroides fragilis in an orthorhombic crystal form.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 1):45-57.
-
1997: Raquet X; Lounnas V; Lamotte-Brasseur J; Frère J M; Wade R C
pKa calculations for class A beta-lactamases: methodological and mechanistic implications.
Biophysical journal 1997;73(5):2416-26.
-
1997: Zhao G H; Duez C; Lepage S; Forceille C; Rhazi N; Klein D; Ghuysen J M; Frère J M
Site-directed mutagenesis of the Actinomadura R39 DD-peptidase.
The Biochemical journal 1997;327 ( Pt 2)():377-81.
-
1997: Adam M; Fraipont C; Rhazi N; Nguyen-Distèche M; Lakaye B; Frère J M; Devreese B; Van Beeumen J; van Heijenoort Y; van Heijenoort J; Ghuysen J M
The bimodular G57-V577 polypeptide chain of the class B penicillin-binding protein 3 of Escherichia coli catalyzes peptide bond formation from thiolesters and does not catalyze glycan chain polymerization from the lipid II intermediate.
Journal of bacteriology 1997;179(19):6005-9.
-
1997: Hernandez Valladares M; Felici A; Weber G; Adolph H W; Zeppezauer M; Rossolini G M; Amicosante G; Frère J M; Galleni M
Zn(II) dependence of the Aeromonas hydrophila AE036 metallo-beta-lactamase activity and stability.
Biochemistry 1997;36(38):11534-41.
-
1997: Ledent P; Duez C; Vanhove M; Lejeune A; Fonzé E; Charlier P; Rhazi-Filali F; Thamm I; Guillaume G; Samyn B; Devreese B; Van Beeumen J; Lamotte-Brasseur J; Frère J M
Unexpected influence of a C-terminal-fused His-tag on the processing of an enzyme and on the kinetic and folding parameters.
FEBS letters 1997;413(2):194-6.
-
1997: Carfí A; Paul-Soto R; Martin L; Pétillot Y; Frère J M; Dideberg O
Purification, crystallization and preliminary X-ray analysis of Bacteroides fragilis Zn2+ beta-lactamase.
Acta crystallographica. Section D, Biological crystallography 1997;53(Pt 4):485-7.
-
1997: Quinting B; Reyrat J M; Monnaie D; Amicosante G; Pelicic V; Gicquel B; Frère J M; Galleni M
Contribution of beta-lactamase production to the resistance of mycobacteria to beta-lactam antibiotics.
FEBS letters 1997;406(3):275-8.
-
1997: Quinting B; Galleni M; Timm J; Gicquel B; Amicosante G; Frère J M
Purification and properties of the Mycobacterium smegmatis mc(2)155 beta-lactamase.
FEMS microbiology letters 1997;149(1):11-5.
-
1997: Jacobs C; Frère J M; Normark S
Cytosolic intermediates for cell wall biosynthesis and degradation control inducible beta-lactam resistance in gram-negative bacteria.
Cell 1997;88(6):823-32.
-
1997: Hardt K; Joris B; Lepage S; Brasseur R; Lampen J O; Frère J M; Fink A L; Ghuysen J M
The penicillin sensory transducer, BlaR, involved in the inducibility of beta-lactamase synthesis in Bacillus licheniformis is embedded in the plasma membrane via a four-alpha-helix bundle.
Molecular microbiology 1997;23(5):935-44.
-
1997: Zhao G H; Frère J M
Reversible inhibition of enzymatic systems involving covalent intermediates.
Journal of enzyme inhibition 1997;11(4):245-64.
-
1997: Guillaume G; Vanhove M; Lamotte-Brasseur J; Ledent P; Jamin M; Joris B; Frère J M
Site-directed mutagenesis of glutamate 166 in two beta-lactamases. Kinetic and molecular modeling studies.
The Journal of biological chemistry 1997;272(9):5438-44.
-
1997: Raquet X; Lamotte-Brasseur J; Bouillenne F; Frère J M
A disulfide bridge near the active site of carbapenem-hydrolyzing class A beta-lactamases might explain their unusual substrate profile.
Proteins 1997;27(1):47-58.
-
1997: Vanhove M; Guillaume G; Ledent P; Richards J H; Pain R H; Frère J M
Kinetic and thermodynamic consequences of the removal of the Cys-77-Cys-123 disulphide bond for the folding of TEM-1 beta-lactamase.
The Biochemical journal 1997;321 ( Pt 2)():413-7.
-
1996: Dubus A; Ledent P; Lamotte-Brasseur J; Frère J M
The roles of residues Tyr150, Glu272, and His314 in class C beta-lactamases.
Proteins 1996;25(4):473-85.
-
1996: Vanhove M; Raquet X; Palzkill T; Pain R H; Frère J M
The rate-limiting step in the folding of the cis-Pro167Thr mutant of TEM-1 beta-lactamase is the trans to cis isomerization of a non-proline peptide bond.
Proteins 1996;25(1):104-11.
-
1996: Damblon C; Raquet X; Lian L Y; Lamotte-Brasseur J; Fonze E; Charlier P; Roberts G C; Frère J M
The catalytic mechanism of beta-lactamases: NMR titration of an active-site lysine residue of the TEM-1 enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(5):1747-52.
-
1996: Mainfroid V; Terpstra P; Beauregard M; Frère J M; Mande S C; Hol W G; Martial J A; Goraj K
Three hTIM mutants that provide new insights on why TIM is a dimer.
Journal of molecular biology 1996;257(2):441-56.
-
1996: Hernandez Villadares M; Galleni M; Frère J M; Felici A; Perilli M; Franceschini N; Rossolini G M; Oratore A; Amicosante G
Overproduction and purification of the Aeromonas hydrophila CphA metallo-beta-lactamase expressed in Escherichia coli.
Microbial drug resistance (Larchmont, N.Y.) 1996;2(2):253-6.
-
1995: Carfi A; Pares S; Duée E; Galleni M; Duez C; Frère J M; Dideberg O
The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold.
The EMBO journal 1995;14(20):4914-21.
-
1995: Fonzé E; Charlier P; To'th Y; Vermeire M; Raquet X; Dubus A; Frère J M
TEM1 beta-lactamase structure solved by molecular replacement and refined structure of the S235A mutant.
Acta crystallographica. Section D, Biological crystallography 1995;51(Pt 5):682-94.
-
1995: Raquet X; Vanhove M; Lamotte-Brasseur J; Goussard S; Courvalin P; Frère J M
Stability of TEM beta-lactamase mutants hydrolyzing third generation cephalosporins.
Proteins 1995;23(1):63-72.
-
1995: Damblon C; Zhao G H; Jamin M; Ledent P; Dubus A; Vanhove M; Raquet X; Christiaens L; Frère J M
Breakdown of the stereospecificity of DD-peptidases and beta-lactamases with thiolester substrates.
The Biochemical journal 1995;309 ( Pt 2)():431-6.
-
1995: Vanhove M; Houba S; b1motte-Brasseur J; Frère J M
Probing the determinants of protein stability: comparison of class A beta-lactamases.
The Biochemical journal 1995;308 ( Pt 3)():859-64.
-
1995: Vanhove M; Raquet X; Frère J M
Investigation of the folding pathway of the TEM-1 beta-lactamase.
Proteins 1995;22(2):110-8.
-
1995: Galleni M; Lamotte-Brasseur J; Raquet X; Dubus A; Monnaie D; Knox J R; Frère J M
The enigmatic catalytic mechanism of active-site serine beta-lactamases.
Biochemical pharmacology 1995;49(9):1171-8.
-
1995: Frère J M
Beta-lactamases and bacterial resistance to antibiotics.
Molecular microbiology 1995;16(3):385-95.
-
1995: Grandchamps J; Nguyen-Distèche M; Damblon C; Frère J M; Ghuysen J M
Streptomyces K15 active-site serine DD-transpeptidase: specificity profile for peptide, thiol ester and ester carbonyl donors and pathways of the transfer reactions.
The Biochemical journal 1995;307 ( Pt 2)():335-9.
-
1995: Lepage S; Lakaye B; Galleni M; Thamm I; Crine M; Groslambert S; Frère J M
Saturation of penicillin-binding protein 1 by beta-lactam antibiotics in growing cells of Bacillus licheniformis.
Molecular microbiology 1995;16(2):365-72.
-
1995: Jacobs C; Joris B; Jamin M; Klarsov K; Van Beeumen J; Mengin-Lecreulx D; van Heijenoort J; Park J T; Normark S; Frère J M
AmpD, essential for both beta-lactamase regulation and cell wall recycling, is a novel cytosolic N-acetylmuramyl-L-alanine amidase.
Molecular microbiology 1995;15(3):553-9.
-
1995: Galleni M; Raquet X; Lamotte-Brasseur J; Fonzé E; Amicosante G; Frère J M
DD-peptidases and beta-lactamases: catalytic mechanisms and specificities.
Journal of chemotherapy (Florence, Italy) 1995;7(1):3-7.
-
1995: Matagne A; Frère J M
Contribution of mutant analysis to the understanding of enzyme catalysis: the case of class A beta-lactamases.
Biochimica et biophysica acta 1995;1246(2):109-27.
-
1995: Matagne A; Ledent P; Monnaie D; Felici A; Jamin M; Raquet X; Galleni M; Klein D; François I; Frère J M
Kinetic study of interaction between BRL 42715, beta-lactamases, and D-alanyl-D-alanine peptidases.
Antimicrobial agents and chemotherapy 1995;39(1):227-31.
-
1995: Jamin M; Wilkin J M; Frère J M
Bacterial DD-transpeptidases and penicillin.
Essays in biochemistry 1995;29():1-24.
-
1994: Raquet X; Lamotte-Brasseur J; Fonzé E; Goussard S; Courvalin P; Frère J M
TEM beta-lactamase mutants hydrolysing third-generation cephalosporins. A kinetic and molecular modelling analysis.
Journal of molecular biology 1994;244(5):625-39.
-
1994: Datz M; Joris B; Azab E A; Galleni M; Van Beeumen J; Frère J M; Martin H H
A common system controls the induction of very different genes. The class-A beta-lactamase of Proteus vulgaris and the enterobacterial class-C beta-lactamase.
European journal of biochemistry / FEBS 1994;226(1):149-57.
-
1994: Duez C; Piron-Fraipont C; Joris B; Dusart J; Urdea M S; Martial J A; Frère J M; Ghuysen J M
Primary structure of the Streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene.
European journal of biochemistry / FEBS 1994;224(3):1079.
-
1994: Fanuel L; Granier B; Wilkin J M; Bellefroid-Bourguignon C; Joris B; Knowles J; Komives E; Van Beeumen J; Ghuysen J M; Frère J M
The precursor of the Streptomyces R61 DD-peptidase containing a C-terminal extension is inactive.
FEBS letters 1994;351(1):49-52.
-
1994: Monnaie D; Dubus A; Frère J M
The role of lysine-67 in a class C beta-lactamase is mainly electrostatic.
The Biochemical journal 1994;302 ( Pt 1)():1-4.
-
1994: Dubus A; Wilkin J M; Raquet X; Normark S; Frère J M
Catalytic mechanism of active-site serine beta-lactamases: role of the conserved hydroxy group of the Lys-Thr(Ser)-Gly triad.
The Biochemical journal 1994;301 ( Pt 2)():485-94.
-
1994: Wilkin J M; Dubus A; Joris B; Frère J M
The mechanism of action of DD-peptidases: the role of Threonine-299 and -301 in the Streptomyces R61 DD-peptidase.
The Biochemical journal 1994;301 ( Pt 2)():477-83.
-
1994: Jamin M; Damblon C; Bauduin-Misselyn A M; Durant F; Roberts G C; Charlier P; Llabres G; Frère J M
Direct n.m.r. evidence for substrate-induced conformational changes in a beta-lactamase.
The Biochemical journal 1994;301 ( Pt 1)():199-203.
-
1994: Galleni M; Franceschini N; Quinting B; Fattorini L; Orefici G; Oratore A; Frère J M; Amicosante G
Use of the chromosomal class A beta-lactamase of Mycobacterium fortuitum D316 to study potentially poor substrates and inhibitory beta-lactam compounds.
Antimicrobial agents and chemotherapy 1994;38(7):1608-14.
-
1994: Monnaie D; Dubus A; Cooke D; Marchand-Brynaert J; Normark S; Frère J M
Role of residue Lys315 in the mechanism of action of the Enterobacter cloacae 908R beta-lactamase.
Biochemistry 1994;33(17):5193-201.
-
1994: Timm J; Perilli M G; Duez C; Trias J; Orefici G; Fattorini L; Amicosante G; Oratore A; Joris B; Frère J M
Transcription and expression analysis, using lacZ and phoA gene fusions, of Mycobacterium fortuitum beta-lactamase genes cloned from a natural isolate and a high-level beta-lactamase producer.
Molecular microbiology 1994;12(3):491-504.
-
1993: Ledent P; Frère J M
Substrate-induced inactivation of the OXA2 beta-lactamase.
The Biochemical journal 1993;295 ( Pt 3)():871-8.
-
1993: Matagne A; Ghuysen M F; Frère J M
Interactions between active-site-serine beta-lactamases and mechanism-based inactivators: a kinetic study and an overview.
The Biochemical journal 1993;295 ( Pt 3)():705-11.
-
1993: Matagne A; Lamotte-Brasseur J; Frère J M
Interactions between active-site serine beta-lactamases and so-called beta-lactamase-stable antibiotics. Kinetic and molecular modelling studies.
European journal of biochemistry / FEBS 1993;217(1):61-7.
-
1993: Matagne A; Lamotte-Brasseur J; Dive G; Knox J R; Frère J M
Interactions between active-site-serine beta-lactamases and compounds bearing a methoxy side chain on the alpha-face of the beta-lactam ring: kinetic and molecular modelling studies.
The Biochemical journal 1993;293 ( Pt 3)():607-11.
-
1993: Jamin M; Wilkin J M; Frère J M
A new kinetic mechanism for the concomitant hydrolysis and transfer reactions catalyzed by bacterial DD-peptidases.
Biochemistry 1993;32(28):7278-85.
-
1993: Dubus A; Monnaie D; Jacobs C; Normark S; Frère J M
A dramatic change in the rate-limiting step of beta-lactam hydrolysis results from the substitution of the active-site serine residue by a cysteine in the class-C beta-lactamase of Enterobacter cloacae 908R.
The Biochemical journal 1993;292 ( Pt 2)():537-43.
-
1993: Ledent P; Raquet X; Joris B; Van Beeumen J; Frère J M
A comparative study of class-D beta-lactamases.
The Biochemical journal 1993;292 ( Pt 2)():555-62.
-
1993: Jamin M; Damblon C; Millier S; Hakenbeck R; Frère J M
Penicillin-binding protein 2x of Streptococcus pneumoniae: enzymic activities and interactions with beta-lactams.
The Biochemical journal 1993;292 ( Pt 3)():735-41.
-
1993: Wilkin J M; Jamin M; Damblon C; Zhao G H; Joris B; Duez C; Frère J M
The mechanism of action of DD-peptidases: the role of tyrosine-159 in the Streptomyces R61 DD-peptidase.
The Biochemical journal 1993;291 ( Pt 2)():537-44.
-
1993: Felici A; Amicosante G; Oratore A; Strom R; Ledent P; Joris B; Fanuel L; Frère J M
An overview of the kinetic parameters of class B beta-lactamases.
The Biochemical journal 1993;291 ( Pt 1)():151-5.
-
1993: Galleni M; Lakaye B; Lepage S; Jamin M; Thamm I; Joris B; Frère J M
A new, highly sensitive method for the detection and quantification of penicillin-binding proteins.
The Biochemical journal 1993;291 ( Pt 1)():19-21.
-
1992: Granier B; Duez C; Lepage S; Englebert S; Dusart J; Dideberg O; Van Beeumen J; Frère J M; Ghuysen J M
Primary and predicted secondary structure of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.
The Biochemical journal 1992;286 ( Pt 3)():981-2.
-
1992: Laible G; Keck W; Lurz R; Mottl H; Frère J M; Jamin M; Hakenbeck R
Penicillin-binding protein 2x of Streptococcus pneumoniae. Expression in Escherichia coli and purification of a soluble enzymatically active derivative.
European journal of biochemistry / FEBS 1992;207(3):943-9.
-
1992: Monnaie D; Virden R; Frère J M
A rapid-kinetic study of the class C beta-lactamase of Enterobacter cloacae 908R.
FEBS letters 1992;306(2-3):108-12.
-
1992: Hadonou A M; Wilkin J M; Varetto L; Joris B; Lamotte-Brasseur J; Klein D; Duez C; Ghuysen J M; Frère J M
Site-directed mutagenesis of the Streptomyces R61 DD-peptidase. Catalytic function of the conserved residues around the active site and a comparison with class-A and class-C beta-lactamases.
European journal of biochemistry / FEBS 1992;207(1):97-102.
-
1992: Jacobs C; Dubus A; Monnaie D; Normark S; Frère J M
Mutation of serine residue 318 in the class C beta-lactamase of Enterobacter cloacae 908R.
FEMS microbiology letters 1992;71(1):95-100.
-
1992: Bourguignon-Bellefroid C; Joris B; Van Beeumen J; Ghuysen J M; Frère J M
Point mutations of two arginine residues in the Streptomyces R61 DD-peptidase.
The Biochemical journal 1992;283 ( Pt 1)():123-8.
-
1992: Granier B; Duez C; Lepage S; Englebert S; Dusart J; Dideberg O; Van Beeumen J; Frère J M; Ghuysen J M
Primary and predicted secondary structures of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.
The Biochemical journal 1992;282 ( Pt 3)():781-8.
-
1992: Hadonou A M; Jamin M; Adam M; Joris B; Dusart J; Ghuysen J M; Frère J M
Importance of the His-298 residue in the catalytic mechanism of the Streptomyces R61 extracellular DD-peptidase.
The Biochemical journal 1992;282 ( Pt 2)():495-500.
-
1992: Bourguignon-Bellefroid C; Wilkin J M; Joris B; Aplin R T; Houssier C; Prendergast F G; Van Beeumen J; Ghuysen J M; Frère J M
Importance of the two tryptophan residues in the Streptomyces R61 exocellular DD-peptidase.
The Biochemical journal 1992;282 ( Pt 2)():361-7.
-
1992: Lamotte-Brasseur J; Jacob-Dubuisson F; Dive G; Frère J M; Ghuysen J M
Streptomyces albus G serine beta-lactamase. Probing of the catalytic mechanism via molecular modelling of mutant enzymes.
The Biochemical journal 1992;282 ( Pt 1)():189-95.
-
1991: Matagne A; Joris B; Frère J M
Anomalous behaviour of a protein during SDS/PAGE corrected by chemical modification of carboxylic groups.
The Biochemical journal 1991;280 ( Pt 2)():553-6.
-
1991: Jamin M; Adam M; Damblon C; Christiaens L; Frère J M
Accumulation of acyl-enzyme in DD-peptidase-catalysed reactions with analogues of peptide substrates.
The Biochemical journal 1991;280 ( Pt 2)():499-506.
-
1991: Joris B; Ledent P; Dideberg O; Fonzé E; Lamotte-Brasseur J; Kelly J A; Ghuysen J M; Frère J M
Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins.
Antimicrobial agents and chemotherapy 1991;35(11):2294-301.
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1991: Lamotte-Brasseur J; Dive G; Dideberg O; Charlier P; Frère J M; Ghuysen J M
Mechanism of acyl transfer by the class A serine beta-lactamase of Streptomyces albus G.
The Biochemical journal 1991;279 ( Pt 1)():213-21.
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1991: Jacob-Dubuisson F; Lamotte-Brasseur J; Dideberg O; Joris B; Frère J M
Arginine 220 is a critical residue for the catalytic mechanism of the Streptomyces albus G beta-lactamase.
Protein engineering 1991;4(7):811-9.
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1991: Brannigan J; Matagne A; Jacob F; Damblon C; Joris B; Klein D; Spratt B G; Frère J M
The mutation Lys234His yields a class A beta-lactamase with a novel pH-dependence.
The Biochemical journal 1991;278 ( Pt 3)():673-8.
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1991: Varetto L; De Meester F; Monnaie D; Marchand-Brynaert J; Dive G; Jacob F; Frère J M
The importance of the negative charge of beta-lactam compounds in the interactions with active-site serine DD-peptidases and beta-lactamases.
The Biochemical journal 1991;278 ( Pt 3)():801-7.
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1991: Perilli M; Franceschini N; Segatore B; Amicosante G; Oratore A; Duez C; Joris B; Frère J M
Cloning and nucleotide sequencing of the gene encoding the beta-lactamase from Citrobacter diversus.
FEMS microbiology letters 1991;67(1):79-84.
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1991: Jacob F; Joris B; Frère J M
Active-site serine mutants of the Streptomyces albus G beta-lactamase.
The Biochemical journal 1991;277 ( Pt 3)():647-52.
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1991: Frère J M; Joris B; Granier B; Matagne A; Jacob F; Bourguignon-Bellefroid C
Diversity of the mechanisms of resistance to beta-lactam antibiotics.
Research in microbiology 1991;142(6):705-10.
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1991: Franceschini N; Amicosante G; Perilli M; Maccarrone M; Oratore A; van Beeumen J; Frère J M
Proteolytic interconversion and N-terminal sequences of the Citrobacter diversus major beta-lactamases.
The Biochemical journal 1991;275 ( Pt 3)():629-33.
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1991: Matagne A; Joris B; Van Beeumen J; Frère J M
Ragged N-termini and other variants of class A beta-lactamases analysed by chromatofocusing.
The Biochemical journal 1991;273 ( Pt 3)():503-10.
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1990: Jacob F; Joris B; Lepage S; Dusart J; Frère J M
Role of the conserved amino acids of the 'SDN' loop (Ser130, Asp131 and Asn132) in a class A beta-lactamase studied by site-directed mutagenesis.
The Biochemical journal 1990;271(2):399-406.
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1990: Jacob F; Joris B; Dideberg O; Dusart J; Ghuysen J M; Frère J M
Engineering a novel beta-lactamase by a single point mutation.
Protein engineering 1990;4(1):79-86.
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1990: Adam M; Damblon C; Plaitin B; Christiaens L; Frère J M
Chromogenic depsipeptide substrates for beta-lactamases and penicillin-sensitive DD-peptidases.
The Biochemical journal 1990;270(2):525-9.
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1990: Matagne A; Misselyn-Bauduin A M; Joris B; Erpicum T; Granier B; Frère J M
The diversity of the catalytic properties of class A beta-lactamases.
The Biochemical journal 1990;265(1):131-46.
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1990: Moews P C; Knox J R; Dideberg O; Charlier P; Frère J M
Beta-lactamase of Bacillus licheniformis 749/C at 2 A resolution.
Proteins 1990;7(2):156-71.
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1989: Houba S; Willem S; Duez C; Molitor C; Dusart J; Frère J M; Ghuysen J M
Nucleotide sequence of the gene encoding the active-site serine beta-lactamase from Actinomadura R39.
FEMS microbiology letters 1989;53(3):241-6.
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1989: Piron-Fraipont C; Duez C; Matagne A; Molitor C; Dusart J; Frère J M; Ghuysen J M
Cloning and amplified expression in Streptomyces lividans of the gene encoding the extracellular beta-lactamase of Actinomadura R39.
The Biochemical journal 1989;262(3):849-54.
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1989: Kelly J A; Knox J R; Zhao H; Frère J M; Ghaysen J M
Crystallographic mapping of beta-lactams bound to a D-alanyl-D-alanine peptidase target enzyme.
Journal of molecular biology 1989;209(2):281-95.
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1989: Frère J M
Quantitative relationship between sensitivity to beta-lactam antibiotics and beta-lactamase production in gram-negative bacteria--I. Steady-state treatment.
Biochemical pharmacology 1989;38(9):1415-26.
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1989: Hechler U; van den Weghe M; Martin H H; Frère J M
Overproduced beta-lactamase and the outer-membrane barrier as resistance factors in Serratia marcescens highly resistant to beta-lactamase-stable beta-lactam antibiotics.
Journal of general microbiology 1989;135(5):1275-90.
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1989: Frère J M; Joris B; Crine M; Martin H H
Quantitative relationship between sensitivity to beta-lactam antibiotics and beta-lactamase production in gram-negative bacteria--II. Non-steady-state treatment and progress curves.
Biochemical pharmacology 1989;38(9):1427-33.
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1989: De Meester F; Matagne A; Dive G; Frère J M
Unexpected influence of ionic strength on branched-pathway interactions between beta-lactamases and beta-halogenopenicillanates.
The Biochemical journal 1989;257(1):245-9.
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1988: Frère J M; Joris B; Dideberg O; Charlier P; Ghuysen J M
Penicillin-recognizing enzymes.
Biochemical Society transactions 1988;16(6):934-8.
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1988: Galleni M; Amicosante G; Frère J M
A survey of the kinetic parameters of class C beta-lactamases. Cephalosporins and other beta-lactam compounds.
The Biochemical journal 1988;255(1):123-9.
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1988: Galleni M; Frère J M
A survey of the kinetic parameters of class C beta-lactamases. Penicillins.
The Biochemical journal 1988;255(1):119-22.
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1988: Amicosante G; Oratore A; Franceschini N; Maccarrone M; Strom R; Galleni M; Frère J M
Citrobacter diversus ULA-27 beta-lactamases. Improved purification and general properties.
The Biochemical journal 1988;254(3):885-90.
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1988: Joris B; Ghuysen J M; Dive G; Renard A; Dideberg O; Charlier P; Frère J M; Kelly J A; Boyington J C; Moews P C
The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family.
The Biochemical journal 1988;250(2):313-24.
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1988: Frère J M; Joris B; Varetto L; Crine M
Structure-activity relationships in the beta-lactam family: an impossible dream.
Biochemical pharmacology 1988;37(1):125-32.
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1988: Frère J M; Joris B
Beta-lactamases as the main resistance factor to penicillin-related antibiotics.
Annales de biologie clinique 1988;46(2):151-6.
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1987: Varetto L; Frère J M; Ghuysen J M
The importance of the negative charge of beta-lactam compounds for the inactivation of the active-site serine DD-peptidase of Streptomyces R61.
FEBS letters 1987;225(1-2):218-22.
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1987: Dideberg O; Charlier P; Wéry J P; Dehottay P; Dusart J; Erpicum T; Frère J M; Ghuysen J M
The crystal structure of the beta-lactamase of Streptomyces albus G at 0.3 nm resolution.
The Biochemical journal 1987;245(3):911-3.
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1987: Dehottay P; Dusart J; De Meester F; Joris B; Van Beeumen J; Erpicum T; Frère J M; Ghuysen J M
Nucleotide sequence of the gene encoding the Streptomyces albus G beta-lactamase precursor.
European journal of biochemistry / FEBS 1987;166(2):345-50.
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1987: De Meester F; Joris B; Reckinger G; Bellefroid-Bourguignon C; Frère J M; Waley S G
Automated analysis of enzyme inactivation phenomena. Application to beta-lactamases and DD-peptidases.
Biochemical pharmacology 1987;36(14):2393-403.
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1987: De Meester F; Joris B; Lenzini M V; Dehottay P; Erpicium T; Dusart J; Klein D; Ghuysen J M; Frère J M; Van Beeumen J
The active sites of the beta-lactamases of Streptomyces cacaoi and Streptomyces albus G.
The Biochemical journal 1987;244(2):427-32.
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1987: Joris B; De Meester F; Galleni M; Frère J M; Van Beeumen J
The K1 beta-lactamase of Klebsiella pneumoniae.
The Biochemical journal 1987;243(2):561-7.
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1987: Duez C; Piron-Fraipont C; Joris B; Dusart J; Urdea M S; Martial J A; Frère J M; Ghuysen J M
Primary structure of the Streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene.
European journal of biochemistry / FEBS 1987;162(3):509-18.
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1986: Joris B; De Meester F; Galleni M; Masson S; Dusart J; Frère J M; Van Beeumen J; Bush K; Sykes R
Properties of a class C beta-lactamase from Serratia marcescens.
The Biochemical journal 1986;239(3):581-6.
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1986: De Meester F; Frère J M; Waley S G; Cartwright S J; Virden R; Lindberg F
6-beta-Iodopenicillanate as a probe for the classification of beta-lactamases.
The Biochemical journal 1986;239(3):575-80.
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1986: Ghuysen J M; Frère J M; Leyh-Bouille M; Nguyen-Distèche M; Coyette J
Active-site-serine D-alanyl-D-alanine-cleaving-peptidase-catalysed acyl-transfer reactions. Procedures for studying the penicillin-binding proteins of bacterial plasma membranes.
The Biochemical journal 1986;235(1):159-65.
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1986: Nguyen-Distèche M; Leyh-Bouille M; Pirlot S; Frère J M; Ghuysen J M
Streptomyces K15 DD-peptidase-catalysed reactions with ester and amide carbonyl donors.
The Biochemical journal 1986;235(1):167-76.
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1986: Dehottay P; Dusart J; Duez C; Lenzini M V; Martial J A; Frère J M; Ghuysen J M; Kieser T
Cloning and amplified expression in Streptomyces lividans of a gene encoding extracellular beta-lactamase from Streptomyces albus G.
Gene 1986;42(1):31-6.
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1985: Kelly J A; Knox J R; Moews P C; Hite G J; Bartolone J B; Zhao H; Joris B; Frère J M; Ghuysen J M
2.8-A Structure of penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase from Streptomyces R61 and complexes with beta-lactams.
The Journal of biological chemistry 1985;260(10):6449-58.
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1985: Lenzini M V; Frère J M
The beta-lactamase of Streptomyces cacaoi: interaction with cefoxitin and beta-iodopenicillanate.
Journal of enzyme inhibition 1985;1(1):25-34.
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1984: Charlier P; Dideberg O; Jamoulle J C; Frère J M; Ghuysen J M; Dive G; Lamotte-Brasseur J
Active-site-directed inactivators of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase of Streptomyces albus G.
The Biochemical journal 1984;219(3):763-72.
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1984: Ghuysen J M; Frère J M; Leyh-Bouille M; Nguyen-Distèche M; Coyette J; Dusart J; Joris B; Duez C; Dideberg O; Charlier P
Bacterial wall peptidoglycan, DD-peptidases and beta-lactam antibiotics.
Scandinavian journal of infectious diseases. Supplementum 1984;42():17-37.
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1983: Charlier P; Dideberg O; Frère J M; Moews P C; Knox J R
Crystallographic data for the beta-lactamase from Enterobacter cloacae P99.
Journal of molecular biology 1983;171(2):237-8.
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1982: Kelly J A; Moews P C; Knox J R; Frère J M; Ghuysen J M
Penicillin target enzyme and the antibiotic binding site.
Science (New York, N.Y.) 1982;218(4571):479-81.
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1982: Dideberg O; Charlier P; Dive G; Joris B; Frère J M; Ghuysen J M
Structure of a Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase at 2.5 A resolution.
Nature 1982;299(5882):469-70.
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