Henry Friedman

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Quinn Jennifer A; Jiang Sara Xiaoyin; Reardon David A; Desjardins Annick; Vredenburgh James J; Friedman Allan H; Sampson John H; McLendon Roger E; Herndon James E; Friedman Henry S
Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy.
Sampson John H; Archer Gary E; Mitchell Duane A; Heimberger Amy B; Herndon James E; Lally-Goss Denise; McGehee-Norman Sharon; Paolino Alison; Reardon David A; Friedman Allan H; Friedman Henry S; Bigner Darell D
An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme.
Friedman Henry S; Prados Michael D; Wen Patrick Y; Mikkelsen Tom; Schiff David; Abrey Lauren E; Yung W K Alfred; Paleologos Nina; Nicholas Martin K; Jensen Randy; Vredenburgh James; Huang Jane; Zheng Maoxia; Cloughesy Timothy
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma.

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2009: Quinn Jennifer A; Jiang Sara Xiaoyin; Reardon David A; Desjardins Annick; Vredenburgh James J; Friedman Allan H; Sampson John H; McLendon Roger E; Herndon James E; Friedman Henry S
Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy.
Journal of neuro-oncology 2009;95(3):393-400.
2009: Sampson John H; Archer Gary E; Mitchell Duane A; Heimberger Amy B; Herndon James E; Lally-Goss Denise; McGehee-Norman Sharon; Paolino Alison; Reardon David A; Friedman Allan H; Friedman Henry S; Bigner Darell D
An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme.
Molecular cancer therapeutics 2009;8(10):2773-9.
2009: Friedman Henry S; Prados Michael D; Wen Patrick Y; Mikkelsen Tom; Schiff David; Abrey Lauren E; Yung W K Alfred; Paleologos Nina; Nicholas Martin K; Jensen Randy; Vredenburgh James; Huang Jane; Zheng Maoxia; Cloughesy Timothy
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(28):4733-40.
2009: Bektas Meryem; Johnson Stewart P; Poe William E; Bigner Darell D; Friedman Henry S
A sphingosine kinase inhibitor induces cell death in temozolomide resistant glioblastoma cells.
Cancer chemotherapy and pharmacology 2009;64(5):1053-8.
2009: Perry Stephanie L; Bohlin Cindy; Reardon David A; Desjardins Annick; Friedman Allan H; Friedman Henry S; Vredenburgh James J
Tinzaparin prophylaxis against venous thromboembolic complications in brain tumor patients.
Journal of neuro-oncology 2009;95(1):129-34.
2009: Quinn Jennifer A; Jiang Sara Xiaoyin; Reardon David A; Desjardins Annick; Vredenburgh James J; Rich Jeremy N; Gururangan Sridharan; Friedman Allan H; Bigner Darell D; Sampson John H; McLendon Roger E; Herndon James E; Walker Amy; Friedman Henry S
Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma.
Neuro-oncology 2009;11(5):556-61.
2009: Affronti Mary Lou; Heery Christopher R; Herndon James E; Rich Jeremy N; Reardon David A; Desjardins Annick; Vredenburgh James J; Friedman Allan H; Bigner Darell D; Friedman Henry S
Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy.
Cancer 2009;115(15):3501-11.
2009: Jones Lee W; Cohen Rachel-Rose; Mabe Stephanie K; West Miranda J; Desjardins Annick; Vredenburgh James J; Friedman Allan H; Reardon David A; Waner Emily; Friedman Henry S
Assessment of physical functioning in recurrent glioma: preliminary comparison of performance status to functional capacity testing.
Journal of neuro-oncology 2009;94(1):79-85.
2009: Quinn Jennifer A; Jiang Sara Xiaoyin; Reardon David A; Desjardins Annick; Vredenburgh James J; Gururangan Sridharan; Sampson John H; McLendon Roger E; Herndon James E; Friedman Henry S
Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma.
Cancer 2009;115(13):2964-70.
2009: Paldino Michael J; Barboriak Daniel; Desjardins Annick; Friedman Henry S; Vredenburgh James J
Repeatability of quantitative parameters derived from diffusion tensor imaging in patients with glioblastoma multiforme.
Journal of magnetic resonance imaging : JMRI 2009;29(5):1199-205.
2009: Reardon David A; Egorin Merrill J; Desjardins Annick; Vredenburgh James J; Beumer Jan H; Lagattuta Theodore F; Gururangan Sridharan; Herndon James E; Salvado August J; Friedman Henry S
Phase I pharmacokinetic study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor vatalanib (PTK787) plus imatinib and hydroxyurea for malignant glioma.
Cancer 2009;115(10):2188-98.
2009: Bacolod Manny D; Fehdrau Randy; Johnson Stewart P; Bullock Nancy S; Bigner Darell D; Colvin Michael; Friedman Henry S
BCNU-sequestration by metallothioneins may contribute to resistance in a medulloblastoma cell line.
Cancer chemotherapy and pharmacology 2009;63(4):753-8.
2009: Vredenburgh James J; Desjardins Annick; Reardon David A; Friedman Henry S
Experience with irinotecan for the treatment of malignant glioma.
Neuro-oncology 2009;11(1):80-91.
2008: Desjardins Annick; Reardon David A; Herndon James E; Marcello Jennifer; Quinn Jennifer A; Rich Jeremy N; Sathornsumetee Sith; Gururangan Sridharan; Sampson John; Bailey Leighann; Bigner Darell D; Friedman Allan H; Friedman Henry S; Vredenburgh James J
Bevacizumab plus irinotecan in recurrent WHO grade 3 malignant gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(21):7068-73.
2008: Schmittling Robert J; Archer Gary E; Mitchell Duane A; Heimberger Amy; Pegram Charles; Herndon James E; Friedman Henry S; Bigner Darell D; Sampson John H
Detection of humoral response in patients with glioblastoma receiving EGFRvIII-KLH vaccines.
Journal of immunological methods 2008;339(1):74-81.
2008: Gururangan Sridharan; Krauser Jeanne; Watral Melody A; Driscoll Tim; Larrier Nicole; Reardon David A; Rich Jeremy N; Quinn Jennifer A; Vredenburgh James J; Desjardins Annick; McLendon Roger E; Fuchs Herbert; Kurtzberg Joanne; Friedman Henry S
Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma.
Neuro-oncology 2008;10(5):745-51.
2008: Maxwell Jill A; Johnson Stewart P; McLendon Roger E; Lister David W; Horne Krystle S; Rasheed Ahmed; Quinn Jennifer A; Ali-Osman Francis; Friedman Allan H; Modrich Paul L; Bigner Darell D; Friedman Henry S
Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4859-68.
2008: Neale Geoffrey; Su Xiaoping; Morton Christopher L; Phelps Doris; Gorlick Richard; Lock Richard B; Reynolds C Patrick; Maris John M; Friedman Henry S; Dome Jeffrey; Khoury Joseph; Triche Timothy J; Seeger Robert C; Gilbertson Richard; Khan Javed; Smith Malcolm A; Houghton Peter J
Molecular characterization of the pediatric preclinical testing panel.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(14):4572-83.
2008: Sampson John H; Akabani Gamal; Archer Gerald E; Berger Mitchel S; Coleman R Edward; Friedman Allan H; Friedman Henry S; Greer Kim; Herndon James E; Kunwar Sandeep; McLendon Roger E; Paolino Alison; Petry Neil A; Provenzale James M; Reardon David A; Wong Terence Z; Zalutsky Michael R; Pastan Ira; Bigner Darell D
Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors.
Neuro-oncology 2008;10(3):320-9.
2008: Reardon David A; Desjardins Annick; Vredenburgh James J; Sathornsumetee Sith; Rich Jeremy N; Quinn Jennifer A; Lagattuta Theodore F; Egorin Merrill J; Gururangan Sridharan; McLendon Roger; Herndon James E; Friedman Allan H; Salvado August J; Friedman Henry S
Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma.
Neuro-oncology 2008;10(3):330-40.
2008: Keir Stephen T; Calhoun-Eagan Roberta D; Swartz Jonas J; Saleh Oussama A; Friedman Henry S
Screening for distress in patients with brain cancer using the NCCN's rapid screening measure.
Psycho-oncology 2008;17(6):621-5.
2008: Bacolod M D; Lin S M; Johnson S P; Bullock N S; Colvin M; Bigner D D; Friedman H S
The gene expression profiles of medulloblastoma cell lines resistant to preactivated cyclophosphamide.
Current cancer drug targets 2008;8(3):172-9.
2008: Everson Richard G; Graner Michael W; Gromeier Matthias; Vredenburgh James J; Desjardins Annick; Reardon David A; Friedman Henry S; Friedman Allan H; Bigner Darell D; Sampson John H
Immunotherapy against angiogenesis-associated targets: evidence and implications for the treatment of malignant glioma.
Expert review of anticancer therapy 2008;8(5):717-32.
2008: Reardon David A; Zalutsky Michael R; Akabani Gamal; Coleman R Edward; Friedman Allan H; Herndon James E; McLendon Roger E; Pegram Charles N; Quinn Jennifer A; Rich Jeremy N; Vredenburgh James J; Desjardins Annick; Guruangan Sridharan; Boulton Susan; Raynor Renee H; Dowell Jeanette M; Wong Terence Z; Zhao Xiao-Guang; Friedman Henry S; Bigner Darell D
A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost.
Neuro-oncology 2008;10(2):182-9.
2008: Gururangan Sridharan; Turner Christopher D; Stewart Clinton F; O'Shaughnessy Melinda; Kocak Mehmet; Poussaint Tina Young; Phillips Peter C; Goldman Stewart; Packer Roger; Pollack Ian F; Blaney Susan M; Karsten Verena; Gerson Stanton L; Boyett James M; Friedman Henry S; Kun Larry E
Phase I trial of VNP40101M (Cloretazine) in children with recurrent brain tumors: a pediatric brain tumor consortium study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1124-30.
2008: Gururangan Sridharan; Frankel Wendy; Broaddus Russell; Clendenning Mark; Senter Leigha; McDonald Marie; Eastwood James; Reardon David; Vredenburgh James; Quinn Jennifer; Friedman Henry S
Multifocal anaplastic astrocytoma in a patient with hereditary colorectal cancer, transcobalamin II deficiency, agenesis of the corpus callosum, mental retardation, and inherited PMS2 mutation.
Neuro-oncology 2008;10(1):93-7.
2008: Sathornsumetee Sith; Cao Yiting; Marcello Jennifer E; Herndon James E; McLendon Roger E; Desjardins Annick; Friedman Henry S; Dewhirst Mark W; Vredenburgh James J; Rich Jeremy N
Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(2):271-8.
2008: Zalutsky Michael R; Reardon David A; Akabani Gamal; Coleman R Edward; Friedman Allan H; Friedman Henry S; McLendon Roger E; Wong Terence Z; Bigner Darell D
Clinical experience with alpha-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(1):30-8.
2007: Keir Stephen T; Swartz Jonas J; Friedman Henry S
Stress and long-term survivors of brain cancer.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2007;15(12):1423-8.
2007: Houghton Peter J; Morton Christopher L; Tucker Chandra; Payne Debbie; Favours Edward; Cole Claire; Gorlick Richard; Kolb E Anders; Zhang Wendong; Lock Richard; Carol Hernan; Tajbakhsh Mimi; Reynolds C Patrick; Maris John M; Courtright Joshua; Keir Stephen T; Friedman Henry S; Stopford Charles; Zeidner Joseph; Wu Jianrong; Liu Tiebin; Billups Catherine A; Khan Javed; Ansher Sherry; Zhang Jian; Smith Malcolm A
The pediatric preclinical testing program: description of models and early testing results.
Pediatric blood & cancer 2007;49(7):928-40.
2007: Johnson Stewart P; Kamen Barton A; Bigner Darell D; Friedman Henry S
O (4)-benzylfolic acid inactivates O (6)-alkylguanine-DNA alkyltransferase in brain tumor cell lines.
Cancer chemotherapy and pharmacology 2007;60(6):883-9.
2007: Bota Daniela A; Desjardins Annick; Quinn Jennifer A; Affronti Mary L; Friedman Henry S
Interstitial chemotherapy with biodegradable BCNU (Gliadel) wafers in the treatment of malignant gliomas.
Therapeutics and clinical risk management 2007;3(5):707-15.
2007: Vredenburgh James J; Desjardins Annick; Herndon James E; Marcello Jennifer; Reardon David A; Quinn Jennifer A; Rich Jeremy N; Sathornsumetee Sith; Gururangan Sridharan; Sampson John; Wagner Melissa; Bailey Leighann; Bigner Darell D; Friedman Allan H; Friedman Henry S
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(30):4722-9.
2007: Hjelmeland Anita B; Lattimore Kathryn P; Fee Brian E; Shi Qing; Wickman Sarah; Keir Stephen T; Hjelmeland Mark D; Batt David; Bigner Darell D; Friedman Henry S; Rich Jeremy N
The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion.
Molecular cancer therapeutics 2007;6(9):2449-57.
2007: Badruddoja Michael A; Keir Stephen T; King Ivan; Zeidner Joseph; Vredenburgh James J; Muhlbaier Lawrence H; Bigner Darell D; Friedman Henry S
Activity of VNP40101M (Cloretazine) in the treatment of CNS tumor xenografts in athymic mice.
Neuro-oncology 2007;9(3):240-4.
2007: Shi Qing; Hjelmeland Anita B; Keir Stephen T; Song Linhua; Wickman Sarah; Jackson Dowdy; Ohmori Osamu; Bigner Darell D; Friedman Henry S; Rich Jeremy N
A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth.
Molecular carcinogenesis 2007;46(6):488-96.
2007: McLendon Roger E; Akabani Gamal; Friedman Henry S; Reardon David A; Cleveland Linda; Cokgor Ilkcan; Herndon James E; Wikstrand Carol; Boulton Susan T; Friedman Allan H; Bigner Darell D; Zalutsky Michael R
Tumor resection cavity administered iodine-131-labeled antitenascin 81C6 radioimmunotherapy in patients with malignant glioma: neuropathology aspects.
Nuclear medicine and biology 2007;34(4):405-13.
2007: Yoshimoto Yasunori; Augustine Christina K; Yoo Jin S; Zipfel Patricia A; Selim M Angelica; Pruitt Scott K; Friedman Henry S; Ali-Osman Francis; Tyler Douglas S
Defining regional infusion treatment strategies for extremity melanoma: comparative analysis of melphalan and temozolomide as regional chemotherapeutic agents.
Molecular cancer therapeutics 2007;6(5):1492-500.
2007: Desjardins Annick; Quinn Jennifer A; Vredenburgh James J; Sathornsumetee Sith; Friedman Allan H; Herndon James E; McLendon Roger E; Provenzale James M; Rich Jeremy N; Sampson John H; Gururangan Sridharan; Dowell Jeannette M; Salvado August; Friedman Henry S; Reardon David A
Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas.
Journal of neuro-oncology 2007;83(1):53-60.
2007: Gururangan Sridharan; Fisher Michael J; Allen Jeffrey C; Herndon James E; Quinn Jennifer A; Reardon David A; Vredenburgh James J; Desjardins Annick; Phillips Peter C; Watral Melody A; Krauser Jeanne M; Friedman Allan H; Friedman Henry S
Temozolomide in children with progressive low-grade glioma.
Neuro-oncology 2007;9(2):161-8.
2007: Jones Lee W; Guill Bebe; Keir Stephen T; Carter Karen; Friedman Henry S; Bigner Darell D; Reardon David A
Using the theory of planned behavior to understand the determinants of exercise intention in patients diagnosed with primary brain cancer.
Psycho-oncology 2007;16(3):232-40.
2007: Vredenburgh James J; Desjardins Annick; Herndon James E; Dowell Jeannette M; Reardon David A; Quinn Jennifer A; Rich Jeremy N; Sathornsumetee Sith; Gururangan Sridharan; Wagner Melissa; Bigner Darell D; Friedman Allan H; Friedman Henry S
Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(4):1253-9.
2007: Sampson John H; Brady Martin L; Petry Neil A; Croteau David; Friedman Allan H; Friedman Henry S; Wong Terence; Bigner Darell D; Pastan Ira; Puri Raj K; Pedain Christoph
Intracerebral infusate distribution by convection-enhanced delivery in humans with malignant gliomas: descriptive effects of target anatomy and catheter positioning.
Neurosurgery 2007;60(2 Suppl 1):ONS89-98; discussion ONS98-9.
2007: Badruddoja Michael A; Penne Kara; Desjardins Annick; Reardon David A; Rich Jeremy N; Quinn Jennifer A; Sathornsumetee Sith; Friedman Allan H; Bigner Darell D; Herndon James E; Cahill Ann; Friedman Henry S; Vredenburgh James J
Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme.
Neuro-oncology 2007;9(1):70-4.
2007: Jones Lee W; Guill Bebe; Keir Stephen T; Carter Karen; Friedman Henry S; Bigner Darell D; Reardon David A
Exercise interest and preferences among patients diagnosed with primary brain cancer.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2007;15(1):47-55.
2006: Keir Stephen T; Guill Ann Bebe; Carter Karen E; Boole Lindsay C; Gonzales Lazaro; Friedman Henry S
Differential levels of stress in caregivers of brain tumor patients--observations from a pilot study.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2006;14(12):1258-61.
2006: Keir Stephen T; Guill Ann Bebe; Carter Karen E; Friedman Henry S
Stress and intervention preferences of patients with brain tumors.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2006;14(12):1213-9.
2006: Ochiai Hidenobu; Pernell Chris T; Archer Gary E; Chewning Tracy A; McLendon Roger E; Friedman Henry S; Sampson John H
Treatment of neoplastic meningitis with intrathecal 9-nitro-camptothecin.
Neurologia medico-chirurgica 2006;46(10):485-9; discussion 489-90.
2006: Maxwell Jill A; Johnson Stewart P; Quinn Jennifer A; McLendon Roger E; Ali-Osman Francis; Friedman Allan H; Herndon James E; Bierau Katja; Bigley Joseph; Bigner Darell D; Friedman Henry S
Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.
Molecular cancer therapeutics 2006;5(10):2531-9.
2006: Sathornsumetee Sith; Hjelmeland Anita B; Keir Stephen T; McLendon Roger E; Batt David; Ramsey Timothy; Yusuff Naeem; Rasheed B K Ahmed; Kieran Mark W; Laforme Andrea; Bigner Darell D; Friedman Henry S; Rich Jeremy N
AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma.
Cancer research 2006;66(17):8722-30.
2006: Reardon David A; Quinn Jennifer A; Akabani Gamal; Coleman R Edward; Friedman Allan H; Friedman Henry S; Herndon James E; McLendon Roger E; Pegram Charles N; Provenzale James M; Dowell Jeannette M; Rich Jeremy N; Vredenburgh James J; Desjardins Annick; Sampson John H; Gururangan Sridharan; Wong Terence Z; Badruddoja Michael A; Zhao Xiao-Guang; Bigner Darell D; Zalutsky Michael R
Novel human IgG2b/murine chimeric antitenascin monoclonal antibody construct radiolabeled with 131I and administered into the surgically created resection cavity of patients with malignant glioma: phase I trial results.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(6):912-8.
2006: Jones Lee W; Guill Bebe; Keir Stephen T; Carter B S Karen; Friedman Henry S; Bigner Darrell D; Reardon David A
Patterns of exercise across the cancer trajectory in brain tumor patients.
Cancer 2006;106(10):2224-32.
2006: Gururangan Sridharan; McLaughlin Colleen A; Brashears James; Watral Melody A; Provenzale James; Coleman R Edward; Halperin Edward C; Quinn Jennifer; Reardon David; Vredenburgh James; Friedman Allan; Friedman Henry S
Incidence and patterns of neuraxis metastases in children with diffuse pontine glioma.
Journal of neuro-oncology 2006;77(2):207-12.
2006: Chintagumpala Murali M; Friedman Henry S; Stewart Clinton F; Kepner James; McLendon Roger E; Modrich Paul L; McCluggage Charles; Burger Peter; Holmes Emi; Thompson Stephen; Rutka James; Michalski Jeff; Woo Shiao; Blaney Susan M; Kun Larry E; Horowitz Marc E;
A phase II window trial of procarbazine and topotecan in children with high-grade glioma: a report from the children's oncology group.
Journal of neuro-oncology 2006;77(2):193-8.
2006: Ueno Tomio; Ko Sae Hee; Grubbs Elizabeth; Yoshimoto Yasunori; Augustine Christi; Abdel-Wahab Zeinab; Cheng Tsung-Yen; Abdel-Wahab Omar I; Pruitt Scott K; Friedman Henry S; Tyler Douglas S
Modulation of chemotherapy resistance in regional therapy: a novel therapeutic approach to advanced extremity melanoma using intra-arterial temozolomide in combination with systemic O6-benzylguanine.
Molecular cancer therapeutics 2006;5(3):732-8.
2006: Gururangan Sridharan; Petros William P; Poussaint Tina Young; Hancock Michael L; Phillips Peter C; Friedman Henry S; Bomgaars Lisa; Blaney Susan M; Kun Larry E; Boyett James M
Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004).
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(5):1540-6.
2006: Reardon David A; Rich Jeremy N; Friedman Henry S; Bigner Darell D
Recent advances in the treatment of malignant astrocytoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(8):1253-65.
2006: Reardon David A; Quinn Jennifer A; Vredenburgh James J; Gururangan Sridharan; Friedman Allan H; Desjardins Annick; Sathornsumetee Sith; Herndon James E; Dowell Jeannette M; McLendon Roger E; Provenzale James M; Sampson John H; Smith Robert P; Swaisland Alan J; Ochs Judith S; Lyons Peggy; Tourt-Uhlig Sandy; Bigner Darell D; Friedman Henry S; Rich Jeremy N
Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(3 Pt 1):860-8.
2006: Vaidyanathan G; Affleck D J; Schottelius M; Wester H; Friedman H S; Zalutsky M R
Synthesis and evaluation of glycosylated octreotate analogues labeled with radioiodine and 211At via a tin precursor.
Bioconjugate chemistry 2006;17(1):195-203.
2006: Ko Sae Hee; Ueno Tomio; Yoshimoto Yasunori; Yoo Jin Soo; Abdel-Wahab Omar I; Abdel-Wahab Zeinab; Chu Edward; Pruitt Scott K; Friedman Henry S; Dewhirst Mark W; Tyler Douglas S
Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):289-97.
2006: Reardon David A; Akabani Gamal; Coleman R Edward; Friedman Allan H; Friedman Henry S; Herndon James E; McLendon Roger E; Pegram Charles N; Provenzale James M; Quinn Jennifer A; Rich Jeremy N; Vredenburgh James J; Desjardins Annick; Gururangan Sridharan; Badruddoja Michael; Dowell Jeanette M; Wong Terence Z; Zhao Xiao-Guang; Zalutsky Michael R; Bigner Darell D
Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: phase II study results.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(1):115-22.
2005: Reardon David A; Egorin Merrill J; Quinn Jennifer A; Rich Jeremy N; Gururangan Sridharan; Vredenburgh James J; Desjardins Annick; Sathornsumetee Sith; Provenzale James M; Herndon James E; Dowell Jeannette M; Badruddoja Michael A; McLendon Roger E; Lagattuta Theodore F; Kicielinski Kimberly P; Dresemann Gregor; Sampson John H; Friedman Allan H; Salvado August J; Friedman Henry S
Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(36):9359-68.
2005: Rich Jeremy N; Sathornsumetee Sith; Keir Stephen T; Kieran Mark W; Laforme Andrea; Kaipainen Arja; McLendon Roger E; Graner Michael W; Rasheed B K Ahmed; Wang Ling; Reardon David A; Ryan Anderson J; Wheeler Catherine; Dimery Isaiah; Bigner Darell D; Friedman Henry S
ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(22):8145-57.
2005: Friedman Henry S; Bigner Darell D
Glioblastoma multiforme and the epidermal growth factor receptor.
The New England journal of medicine 2005;353(19):1997-9.
2005: Quinn Jennifer A; Desjardins Annick; Weingart Jon; Brem Henry; Dolan M Eileen; Delaney Shannon M; Vredenburgh James; Rich Jeremy; Friedman Allan H; Reardon David A; Sampson John H; Pegg Anthony E; Moschel Robert C; Birch Robert; McLendon Roger E; Provenzale James M; Gururangan Sridharan; Dancey Janet E; Maxwell Jill; Tourt-Uhlig Sandra; Herndon James E; Bigner Darell D; Friedman Henry S
Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(28):7178-87.
2005: McLendon Roger E; Herndon James E; West Bryan; Reardon David; Wiltshire Rodney; Rasheed B K Ahmed; Quinn Jennifer; Friedman Henry S; Friedman Allan H; Bigner Darell D
Survival analysis of presumptive prognostic markers among oligodendrogliomas.
Cancer 2005;104(8):1693-9.
2005: Reardon David A; Quinn Jennifer A; Rich Jeremy N; Desjardins Annick; Vredenburgh James; Gururangan Sridharan; Sathornsumetee Sith; Badruddoja Michael; McLendon Roger; Provenzale James; Herndon James E; Dowell Jeannette M; Burkart Jill L; Newton Herbert B; Friedman Allan H; Friedman Henry S
Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma.
Cancer 2005;104(7):1478-86.
2005: Cheng C Lynn; Johnson Stewart P; Keir Stephen T; Quinn Jennifer A; Ali-Osman Francis; Szabo Csaba; Li Hongshan; Salzman Andrew L; Dolan M Eileen; Modrich Paul; Bigner Darell D; Friedman Henry S
Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft.
Molecular cancer therapeutics 2005;4(9):1364-8.
2005: Akabani Gamal; Reardon David A; Coleman R Edward; Wong Terence Z; Metzler Scott D; Bowsher James E; Barboriak Daniel P; Provenzale James M; Greer Kim L; DeLong David; Friedman Henry S; Friedman Allan H; Zhao Xiao-Guang; Pegram Charles N; McLendon Roger E; Bigner Darell D; Zalutsky Michael R
Dosimetry and radiographic analysis of 131I-labeled anti-tenascin 81C6 murine monoclonal antibody in newly diagnosed patients with malignant gliomas: a phase II study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(6):1042-51.
2005: Sampson John H; Reardon David A; Friedman Allan H; Friedman Henry S; Coleman R Edward; McLendon Roger E; Pastan Ira; Bigner Darell D
Sustained radiographic and clinical response in patient with bifrontal recurrent glioblastoma multiforme with intracerebral infusion of the recombinant targeted toxin TP-38: case study.
Neuro-oncology 2005;7(1):90-6.
2005: Goudar Ranjit K; Shi Qing; Hjelmeland Mark D; Keir Stephen T; McLendon Roger E; Wikstrand Carol J; Reese Elizabeth D; Conrad Charles A; Traxler Peter; Lane Heidi A; Reardon David A; Cavenee Webster K; Wang Xiao-Fan; Bigner Darell D; Friedman Henry S; Rich Jeremy N
Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition.
Molecular cancer therapeutics 2005;4(1):101-12.
2005: Reardon David A; Quinn Jennifer A; Vredenburgh James; Rich Jeremy N; Gururangan Sridharan; Badruddoja Michael; Herndon James E; Dowell Jeannette M; Friedman Allan H; Friedman Henry S
Phase II trial of irinotecan plus celecoxib in adults with recurrent malignant glioma.
Cancer 2005;103(2):329-38.
2005: Desjardins Annick; Rich Jeremy N; Quinn Jennifer A; Vredenburgh James; Gururangan Sridharan; Sathornsumetee Sith; Reardon David A; Friedman Allan H; Bigner Darell D; Friedman Henry S
Chemotherapy and novel therapeutic approaches in malignant glioma.
Frontiers in bioscience : a journal and virtual library 2005;10():2645-68.
2004: Shi Qing; Bao Shideng; Maxwell Jill A; Reese Elizabeth D; Friedman Henry S; Bigner Darell D; Wang Xiao-Fan; Rich Jeremy N
Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation.
The Journal of biological chemistry 2004;279(50):52200-9.
2004: Gururangan Sri; Friedman Henry S
Recent advances in the treatment of pediatric brain tumors.
Oncology (Williston Park, N.Y.) 2004;18(13):1649-61; discussion 1662, 1665-6, 1668.
2004: Ueno Tomio; Ko Sae Hee; Grubbs Elizabeth; Pruitt Scott K; Friedman Henry S; Tyler Douglas S
Temozolomide is a novel regional infusion agent for the treatment of advanced extremity melanoma.
American journal of surgery 2004;188(5):532-7.
2004: Vaidyanathan Ganesan; Welsh Philip C; Vitorello Katia C; Snyder Stacey; Friedman Henry S; Zalutsky Michael R
A 4-methyl-substituted meta-iodobenzylguanidine analogue with prolonged retention in human neuroblastoma cells.
European journal of nuclear medicine and molecular imaging 2004;31(10):1362-70.
2004: Bacolod Manny D; Johnson Stewart P; Pegg Anthony E; Dolan M Eileen; Moschel Robert C; Bullock Nancy S; Fang Qingming; Colvin O Michael; Modrich Paul; Bigner Darell D; Friedman Henry S
Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations.
Molecular cancer therapeutics 2004;3(9):1127-35.
2004: Grubbs Elizabeth G; Abdel-Wahab Omar; Cheng Tsung-Yen; Abdel-Wahab Zeinab; Peterson Bercedis; Pruitt Scott K; Colvin O Michael; Friedman Henry S; Tyler Douglas S
In-transit melanoma: the role of alkylating-agent resistance in regional therapy.
Journal of the American College of Surgeons 2004;199(3):419-27.
2004: Grubbs Elizabeth G; Ueno Tomio; Abdel-Wahab Omar; Cheng Tsung-Yen; Pruitt Scott K; Michael Colvin O; Friedman Henry S; Tyler Douglas S
Modulation of resistance to regional chemotherapy in the extremity melanoma model.
Surgery 2004;136(2):210-8.
2004: Wiltshire Rodney N; Herndon James E; Lloyd Annie; Friedman Henry S; Bigner Darell D; Bigner Sandra H; McLendon Roger E
Comparative genomic hybridization analysis of astrocytomas: prognostic and diagnostic implications.
The Journal of molecular diagnostics : JMD 2004;6(3):166-79.
2004: Hjelmeland Mark D; Hjelmeland Anita B; Sathornsumetee Sith; Reese Elizabeth D; Herbstreith Michael H; Laping Nicholas J; Friedman Henry S; Bigner Darell D; Wang Xiao-Fan; Rich Jeremy N
SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility.
Molecular cancer therapeutics 2004;3(6):737-45.
2004: Learn Chris A; Hartzell Tristan L; Wikstrand Carol J; Archer Gary E; Rich Jeremy N; Friedman Allan H; Friedman Henry S; Bigner Darell D; Sampson John H
Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):3216-24.
2004: Quinn Jennifer A; Reardon David A; Friedman Allan H; Rich Jeremy N; Sampson John H; Vredenburgh James; Gururangan Sridharan; Provenzale James M; Walker Amy; Schweitzer Holly; Bigner Darell D; Tourt-Uhlig Sandra; Herndon James E; Affronti Mary Lou; Jackson Susanne; Allen Deborah; Ziegler Karen; Bohlin Cindy; Lentz Christy; Friedman Henry S
Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma.
Neuro-oncology 2004;6(2):145-53.
2004: Reardon David A; Quinn Jennifer A; Rich Jeremy N; Gururangan Sridharan; Vredenburgh James; Sampson John H; Provenzale James M; Walker Amy; Badruddoja Michael; Tourt-Uhlig Sandra; Herndon James E; Dowell Jeannette M; Affronti Mary Lou; Jackson Susanne; Allen Deborah; Ziegler Karen; Silverman Steven; Bohlin Cindy; Friedman Allan H; Bigner Darell D; Friedman Henry S
Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma.
Neuro-oncology 2004;6(2):134-44.
2004: Vaidyanathan Ganesan; Affleck Donna J; Norman Joseph; Welsh Phil; Liu Wenge; Johnson Stewart P; Friedman Henry S; Zalutsky Michael R
O6-3-[131I]iodobenzylguanine: improved synthesis and further evaluation of a potential agent for imaging of alkylguanine-DNA alkyltransferase.
Bioconjugate chemistry 2004;15(2):402-8.
2004: Rich Jeremy N; Reardon David A; Peery Terry; Dowell Jeannette M; Quinn Jennifer A; Penne Kara L; Wikstrand Carol J; Van Duyn Lauren B; Dancey Janet E; McLendon Roger E; Kao James C; Stenzel Timothy T; Ahmed Rasheed B K; Tourt-Uhlig Sandra E; Herndon James E; Vredenburgh James J; Sampson John H; Friedman Allan H; Bigner Darell D; Friedman Henry S
Phase II trial of gefitinib in recurrent glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(1):133-42.
2003: Grossi Peter M; Ochiai Hidenobu; Archer Gary E; McLendon Roger E; Zalutsky Michael R; Friedman Allan H; Friedman Henry S; Bigner Darell D; Sampson John H
Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5514-20.
2003: Sampson John H; Akabani Gamal; Archer Gary E; Bigner Darell D; Berger Mitchel S; Friedman Allan H; Friedman Henry S; Herndon James E; Kunwar Sandeep; Marcus Steve; McLendon Roger E; Paolino Alison; Penne Kara; Provenzale James; Quinn Jennifer; Reardon David A; Rich Jeremy; Stenzel Timothy; Tourt-Uhlig Sandra; Wikstrand Carol; Wong Terence; Williams Roger; Yuan Fan; Zalutsky Michael R; Pastan Ira
Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors.
Journal of neuro-oncology 2003;65(1):27-35.
2003: Dreyer ZoAnn E; Kadota Richard P; Stewart Clinton F; Friedman Henry S; Mahoney Donald H; Kun Larry E; McCluggage Charles W; Burger Peter C; Kepner James; Heideman Richard L;
Phase 2 study of idarubicin in pediatric brain tumors: Pediatric Oncology Group study POG 9237.
Neuro-oncology 2003;5(4):261-7.
2003: Heimberger Amy B; Crotty Laura E; Archer Gary E; Hess Kenneth R; Wikstrand Carol J; Friedman Allan H; Friedman Henry S; Bigner Darell D; Sampson John H
Epidermal growth factor receptor VIII peptide vaccination is efficacious against established intracerebral tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(11):4247-54.
2003: Flowers James L; Hoffman Robert M; Driscoll Timothy A; Wall Monroe E; Wani Mansukh C; Manikumar Govindarajan; Friedman Henry S; Dewhirst Mark; Colvin O Michael; Adams David J
The activity of camptothecin analogues is enhanced in histocultures of human tumors and human tumor xenografts by modulation of extracellular pH.
Cancer chemotherapy and pharmacology 2003;52(3):253-61.
2003: Gururangan Sridharan; McLaughlin Colleen; Quinn Jennifer; Rich Jeremy; Reardon David; Halperin Edward C; Herndon James; Fuchs Herbert; George Timothy; Provenzale James; Watral Melody; McLendon Roger E; Friedman Allan; Friedman Henry S; Kurtzberg Joanne; Vredenbergh James; Martin Paul L
High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(11):2187-91.
2003: Reardon David A; Friedman Henry S; Powell James B; Gilbert Mark; Yung W K
Irinotecan: promising activity in the treatment of malignant glioma.
Oncology (Williston Park, N.Y.) 2003;17(5 Suppl 5):9-14.
2003: Vaidyanathan Ganesan; Friedman Henry S; Affleck Donna J; Schottelius Margaret; Wester Hans-Jürgen; Zalutsky Michael R
Specific and high-level targeting of radiolabeled octreotide analogues to human medulloblastoma xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(5):1868-76.
2003: Friedman Henry S; Keir Stephen T; Houghton Peter J
The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.
Cancer 2003;97(9 Suppl):2359-62.
2003: Quinn Jennifer A; Reardon David A; Friedman Allan H; Rich Jeremy N; Sampson John H; Provenzale James M; McLendon Roger E; Gururangan Sridharan; Bigner Darell D; Herndon James E; Avgeropoulos Nicholas; Finlay Jonathan; Tourt-Uhlig Sandra; Affronti Mary Lou; Evans Brandon; Stafford-Fox Valerie; Zaknoen Sara; Friedman Henry S
Phase II trial of temozolomide in patients with progressive low-grade glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(4):646-51.
2003: McGirt Matthew J; Bulsara Ketan R; Cummings Thomas J; New Kent C; Little Kenneth M; Friedman Henry S; Friedman Allan H
Prognostic value of magnetic resonance imaging-guided stereotactic biopsy in the evaluation of recurrent malignant astrocytoma compared with a lesion due to radiation effect.
Journal of neurosurgery 2003;98(1):14-20.
2002: Gururangan Sridharan; Friedman Henry S
Innovations in design and delivery of chemotherapy for brain tumors.
Neuroimaging clinics of North America 2002;12(4):583-97.
2002: Heimberger Amy B; Learn Chris A; Archer Gary E; McLendon Roger E; Chewning Tracy A; Tuck Frank L; Pracyk John B; Friedman Allan H; Friedman Henry S; Bigner Darell D; Sampson John H
Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(11):3496-502.
2002: Cokgor Ilkcan; Friedman Allan H; Friedman Henry S
Current options for the treatment of neoplastic meningitis.
Journal of neuro-oncology 2002;60(1):79-88.
2002: Gilbert Mark R; Friedman Henry S; Kuttesch John F; Prados Michael D; Olson Jeffrey J; Reaman Gregory H; Zaknoen Sara L
A phase II study of temozolomide in patients with newly diagnosed supratentorial malignant glioma before radiation therapy.
Neuro-oncology 2002;4(4):261-7.
2002: Friedman Henry S; Keir Stephen; Pegg Anthony E; Houghton Peter J; Colvin O Michael; Moschel Robert C; Bigner Darell D; Dolan M Eileen
O6-benzylguanine-mediated enhancement of chemotherapy.
Molecular cancer therapeutics 2002;1(11):943-8.
2002: Leggas Markos; Stewart Clinton F; Woo Michael H; Fouladi Maryam; Cheshire Pamela J; Peterson Jennifer K; Friedman Henry S; Billups Catherine; Houghton Peter J
Relation between Irofulven (MGI-114) systemic exposure and tumor response in human solid tumor xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):3000-7.
2002: Bacolod Manny D; Johnson Stewart P; Ali-Osman Francis; Modrich Paul; Bullock Nancy S; Colvin O Michael; Bigner Darell D; Friedman Henry S
Mechanisms of resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea in human medulloblastoma and rhabdomyosarcoma.
Molecular cancer therapeutics 2002;1(9):727-36.
2002: Gururangan Sridharan; Cavazos Christina M; Ashley David; Herndon James E; Bruggers Carol S; Moghrabi Albert; Scarcella Deborah L; Watral Melody; Tourt-Uhlig Sandra; Reardon David; Friedman Henry S
Phase II study of carboplatin in children with progressive low-grade gliomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(13):2951-8.
2002: Lal Anita; Glazer Chad A; Martinson Holly M; Friedman Henry S; Archer Gary E; Sampson John H; Riggins Gregory J
Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion.
Cancer research 2002;62(12):3335-9.
2002: Rasheed Ahmed; Herndon James E; Stenzel Timothy T; Raetz Jacqueline G M; Kendelhardt Jason; Friedman Henry S; Friedman Allan H; Bigner Darell D; Bigner Sandra H; McLendon Roger E
Molecular markers of prognosis in astrocytic tumors.
Cancer 2002;94(10):2688-97.
2002: McGirt Matthew J; Villavicencio Alan T; Bulsara Ketan R; Friedman Henry S; Friedman Allan H
Management of tumor bed cysts after chemotherapeutic wafer implantation. Report of four cases.
Journal of neurosurgery 2002;96(5):941-5.
2002: Quinn Jennifer A; Pluda James; Dolan M Eileen; Delaney Shannon; Kaplan Richard; Rich Jeremy N; Friedman Allan H; Reardon David A; Sampson John H; Colvin O Michael; Haglund Michael M; Pegg Anthony E; Moschel Robert C; McLendon Roger E; Provenzale James M; Gururangan Sridharan; Tourt-Uhlig Sandra; Herndon James E; Bigner Darell D; Friedman Henry S
Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(9):2277-83.
2002: Aldosari Naji; Bigner Sandra H; Burger Peter C; Becker Laurence; Kepner James L; Friedman Henry S; McLendon Roger E
MYCC and MYCN oncogene amplification in medulloblastoma. A fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group.
Archives of pathology & laboratory medicine 2002;126(5):540-4.
2002: Turner Christopher D; Gururangan Sridharan; Eastwood James; Bottom Krystal; Watral Melody; Beason Rodney; McLendon Roger E; Friedman Allan H; Tourt-Uhlig Sandra; Miller Langdon L; Friedman Henry S
Phase II study of irinotecan (CPT-11) in children with high-risk malignant brain tumors: the Duke experience.
Neuro-oncology 2002;4(2):102-8.
2002: Aldosari Naji; Wiltshire Rodney N; Dutra Amalia; Schrock Evelin; McLendon Roger E; Friedman Henry S; Bigner Darell D; Bigner Sandra H
Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft.
Neuro-oncology 2002;4(2):75-85.
2002: Reardon David A; Akabani Gamal; Coleman R Edward; Friedman Allan H; Friedman Henry S; Herndon James E; Cokgor Ilkcan; McLendon Roger E; Pegram Charles N; Provenzale James M; Quinn Jennifer A; Rich Jeremy N; Regalado Lorna V; Sampson John H; Shafman Timothy D; Wikstrand Carol J; Wong Terence Z; Zhao Xiao-Guang; Zalutsky Michael R; Bigner Darell D
Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(5):1389-97.
2002: Eberhart Charles G; Kepner James L; Goldthwaite Patricia T; Kun Larry E; Duffner Patricia K; Friedman Henry S; Strother Douglas R; Burger Peter C
Histopathologic grading of medulloblastomas: a Pediatric Oncology Group study.
Cancer 2002;94(2):552-60.
2002: Heimberger Amy B; Archer Gary E; Crotty Laura E; McLendon Roger E; Friedman Allan H; Friedman Henry S; Bigner Darell D; Sampson John H
Dendritic cells pulsed with a tumor-specific peptide induce long-lasting immunity and are effective against murine intracerebral melanoma.
Neurosurgery 2002;50(1):158-64; discussion 164-6.
2002: Friedman Henry S; Johnson Stewart P; Colvin O Michael
Cellular mechanisms of cyclophosphamide resistance: model studies in human medulloblastoma cell lines.
Cancer treatment and research 2002;112():199-209.
2001: DeGrado T R; Baldwin S W; Wang S; Orr M D; Liao R P; Friedman H S; Reiman R; Price D T; Coleman R E
Synthesis and evaluation of (18)F-labeled choline analogs as oncologic PET tracers.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(12):1805-14.
2001: Friedman H S; Keir S T; Houghton P J; Lawless A A; Bigner D D; Waters S J
Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice.
Cancer chemotherapy and pharmacology 2001;48(5):413-6.
2001: Gururangan S; Cokgor L; Rich J N; Edwards S; Affronti M L; Quinn J A; Herndon J E; Provenzale J M; McLendon R E; Tourt-Uhlig S; Sampson J H; Stafford-Fox V; Zaknoen S; Early M; Friedman A H; Friedman H S
Phase I study of Gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas.
Neuro-oncology 2001;3(4):246-50.
2001: Keir S T; Hausheer F; Lawless A A; Bigner D D; Friedman H S
Therapeutic activity of 7-[(2-trimethylsilyl)ethyl)]-20 (S)-camptothecin against central nervous system tumor-derived xenografts in athymic mice.
Cancer chemotherapy and pharmacology 2001;48(1):83-7.
2001: Struck R F; Tiwari A; Friedman H S; Keir S; Morgan L R; Waud W R
Acyl derivatives of demethylpenclomedine, an antitumor-active, non-neurotoxic metabolites of penclomedine.
Cancer chemotherapy and pharmacology 2001;48(1):47-52.
2001: Cokgor I; Akabani G; Friedman H S; Friedman A H; Zalutsky M R; Zehngebot L M; Provenzale J M; Guy C D; Wikstrand C J; Bigner D D
Long term response in a patient with neoplastic meningitis secondary to melanoma treated with (131)I-radiolabeled antichondroitin proteoglycan sulfate Mel-14 F(ab')(2): a case study.
Cancer 2001;91(9):1809-13.
2001: Ewesuedo R B; Wilson L R; Friedman H S; Moschel R C; Dolan M E
Inactivation of O6-alkylguanine-DNA alkyltransferase by 8-substituted O6-benzylguanine analogs in mice.
Cancer chemotherapy and pharmacology 2001;47(1):63-9.
2000: Vaidyanathan G; Affleck D J; Cavazos C M; Johnson S P; Shankar S; Friedman H S; Colvin M O; Zalutsky M R
Radiolabeled guanine derivatives for the in vivo mapping of O(6)-alkylguanine-DNA alkyltransferase: 6-(4-[(18)F]Fluoro-benzyloxy)-9H-purin-2-ylamine and 6-(3-[(131)I]Iodo-benzyloxy)-9H-purin-2-ylamine.
Bioconjugate chemistry 2000;11(6):868-75.
2000: Cokgor I; Akabani G; Kuan C T; Friedman H S; Friedman A H; Coleman R E; McLendon R E; Bigner S H; Zhao X G; Garcia-Turner A M; Pegram C N; Wikstrand C J; Shafman T D; Herndon J E; Provenzale J M; Zalutsky M R; Bigner D D
Phase I trial results of iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with newly diagnosed malignant gliomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(22):3862-72.
2000: Mahoney D H; Cohen M E; Friedman H S; Kepner J L; Gemer L; Langston J W; James H E; Duffner P K; Kun L E
Carboplatin is effective therapy for young children with progressive optic pathway tumors: a Pediatric Oncology Group phase II study.
Neuro-oncology 2000;2(4):213-20.
2000: Brown H G; Kepner J L; Perlman E J; Friedman H S; Strother D R; Duffner P K; Kun L E; Goldthwaite P T; Burger P C
"Large cell/anaplastic" medulloblastomas: a Pediatric Oncology Group Study.
Journal of neuropathology and experimental neurology 2000;59(10):857-65.
2000: Patel V J; Elion G B; Houghton P J; Keir S; Pegg A E; Johnson S P; Dolan M E; Bigner D D; Friedman H S
Schedule-dependent activity of temozolomide plus CPT-11 against a human central nervous system tumor-derived xenograft.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(10):4154-7.
2000: Heimberger A B; Archer G E; McLendon R E; Hulette C; Friedman A H; Friedman H S; Bigner D D; Sampson J H
Temozolomide delivered by intracerebral microinfusion is safe and efficacious against malignant gliomas in rats.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(10):4148-53.
2000: Houghton P J; Stewart C F; Cheshire P J; Richmond L B; Kirstein M N; Poquette C A; Tan M; Friedman H S; Brent T P
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(10):4110-8.
2000: Friedman H S; Pluda J; Quinn J A; Ewesuedo R B; Long L; Friedman A H; Cokgor I; Colvin O M; Haglund M M; Ashley D M; Rich J N; Sampson J; Pegg A E; Moschel R C; McLendon R E; Provenzale J M; Stewart E S; Tourt-Uhlig S; Garcia-Turner A M; Herndon J E; Bigner D D; Dolan M E
Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(20):3522-8.
2000: Thomas P R; Deutsch M; Kepner J L; Boyett J M; Krischer J; Aronin P; Albright L; Allen J C; Packer R J; Linggood R; Mulhern R; Stehbens J A; Langston J; Stanley P; Duffner P; Rorke L; Cherlow J; Friedman H S; Finlay J L; Vietti T J; Kun L E
Low-stage medulloblastoma: final analysis of trial comparing standard-dose with reduced-dose neuraxis irradiation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(16):3004-11.
2000: Wiltshire R N; Rasheed B K; Friedman H S; Friedman A H; Bigner S H
Comparative genetic patterns of glioblastoma multiforme: potential diagnostic tool for tumor classification.
Neuro-oncology 2000;2(3):164-73.
2000: Friedman H S; Kerby T; Calvert H
Temozolomide and treatment of malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2585-97.
2000: Friedman H S
Temozolomide in early stages of newly diagnosed malignant glioma and neoplastic meningitis.
Seminars in oncology 2000;27(3 Suppl 6):35-40.
2000: Sampson J H; Crotty L E; Lee S; Archer G E; Ashley D M; Wikstrand C J; Hale L P; Small C; Dranoff G; Friedman A H; Friedman H S; Bigner D D
Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7503-8.
2000: Aldosari N; Rasheed B K; McLendon R E; Friedman H S; Bigner D D; Bigner S H
Characterization of chromosome 17 abnormalities in medulloblastomas.
Acta neuropathologica 2000;99(4):345-51.
2000: Middlemas D S; Stewart C F; Kirstein M N; Poquette C; Friedman H S; Houghton P J; Brent T P
Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):998-1007.
2000: Akabani G; Cokgor I; Coleman R E; González Trotter D; Wong T Z; Friedman H S; Friedman A H; Garcia-Turner A; Herndon J E; DeLong D; McLendon R E; Zhao X G; Pegram C N; Provenzale J M; Bigner D D; Zalutsky M R
Dosimetry and dose-response relationships in newly diagnosed patients with malignant gliomas treated with iodine-131-labeled anti-tenascin monoclonal antibody 81C6 therapy.
International journal of radiation oncology, biology, physics 2000;46(4):947-58.
2000: Bottom K S; Ashley D M; Friedman H S; Longee D C
Evaluation of pre-radiotherapy cyclophosphamide in patients with newly diagnosed glioblastoma multiforme. Writing Committee for The Brain Tumor Center at Duke.
Journal of neuro-oncology 2000;46(2):151-6.
2000: Keir S T; Dolan M E; Pegg A E; Lawless A; Moschel R C; Bigner D D; Friedman H S
O6-benzylguanine-mediated enhancement of nitrosourea activity in Mer- central nervous system tumor xenografts--implications for clinical trials.
Cancer chemotherapy and pharmacology 2000;45(6):437-40.
2000: Castellino R C; Elion G B; Keir S T; Houghton P J; Johnson S P; Bigner D D; Friedman H S
Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts.
Cancer chemotherapy and pharmacology 2000;45(4):345-9.
1999: Yung W K; Prados M D; Yaya-Tur R; Rosenfeld S S; Brada M; Friedman H S; Albright R; Olson J; Chang S M; O'Neill A M; Friedman A H; Bruner J; Yue N; Dugan M; Zaknoen S; Levin V A
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(9):2762-71.
1999: Archer G E; Sampson J H; Lorimer I A; McLendon R E; Kuan C T; Friedman A H; Friedman H S; Pastan I H; Bigner D D
Regional treatment of epidermal growth factor receptor vIII-expressing neoplastic meningitis with a single-chain immunotoxin, MR-1.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(9):2646-52.
1999: Bigner S H; Matthews M R; Rasheed B K; Wiltshire R N; Friedman H S; Friedman A H; Stenzel T T; Dawes D M; McLendon R E; Bigner D D
Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization.
The American journal of pathology 1999;155(2):375-86.
1999: Kadota R P; Stewart C F; Horn M; Kuttesch J F; Burger P C; Kepner J L; Kun L E; Friedman H S; Heideman R L
Topotecan for the treatment of recurrent or progressive central nervous system tumors - a pediatric oncology group phase II study.
Journal of neuro-oncology 1999;43(1):43-7.
1999: Kadota R P; Kun L E; Langston J W; Burger P C; Cohen M E; Mahoney D H; Walter A W; Rodman J H; Parent A; Buckley E; Kepner J L; Friedman H S
Cyclophosphamide for the treatment of progressive low-grade astrocytoma: a Pediatric Oncology Group phase II Study.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology 1999;21(3):198-202.
1999: Sampson J H; Archer G E; Villavicencio A T; McLendon R E; Friedman A H; Bishop W R; Bigner D D; Friedman H S
Treatment of neoplastic meningitis with intrathecal temozolomide.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(5):1183-8.
1999: Friedman H S; Petros W P; Friedman A H; Schaaf L J; Kerby T; Lawyer J; Parry M; Houghton P J; Lovell S; Rasheed K; Cloughsey T; Stewart E S; Colvin O M; Provenzale J M; McLendon R E; Bigner D D; Cokgor I; Haglund M; Rich J; Ashley D; Malczyn J; Elfring G L; Miller L L
Irinotecan therapy in adults with recurrent or progressive malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(5):1516-25.
1999: Duffner P K; Horowitz M E; Krischer J P; Burger P C; Cohen M E; Sanford R A; Friedman H S; Kun L E
The treatment of malignant brain tumors in infants and very young children: an update of the Pediatric Oncology Group experience.
Neuro-oncology 1999;1(2):152-61.
1999: Akabani G; Reist C J; Cokgor I; Friedman A H; Friedman H S; Coleman R E; Zhao X G; Bigner D D; Zalutsky M R
Dosimetry of 131I-labeled 81C6 monoclonal antibody administered into surgically created resection cavities in patients with malignant brain tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(4):631-8.
1999: Friedman H S; Kerby T; Fields S; Zilisch J E; Graden D; McLendon R E; Houghton P J; Arbuck S; Cokgor I; Friedman A H
Topotecan treatment of adults with primary malignant glioma. The Brain Tumor Center at Duke.
Cancer 1999;85(5):1160-5.
1999: McLendon R E; Friedman H S; Fuchs H E; Kun L E; Bigner S H
Diagnostic markers in paediatric medulloblastoma: a Paediatric Oncology Group Study.
Histopathology 1999;34(2):154-62.
1999: Wu M H; Lohrbach K E; Olopade O I; Kokkinakis D M; Friedman H S; Dolan M E
Lack of evidence for a polymorphism at codon 160 of human O6-alkylguanine-DNA alkyltransferase gene in normal tissue and cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):209-13.
1999: Archer G E; Sampson J H; McLendon R E; Friedman A H; Colvin O M; Rose M; Sands H; McCullough W; Fuchs H E; Bigner D D; Friedman H S
Intrathecal busulfan treatment of human neoplastic meningitis in athymic nude rats.
Journal of neuro-oncology 1999;44(3):233-41.
1999: Cokgor I; Friedman H S; Friedman A H
Chemotherapy for adults with malignant glioma.
Cancer investigation 1999;17(4):264-72.
1999: Friedman H S; Pegg A E; Johnson S P; Loktionova N A; Dolan M E; Modrich P; Moschel R C; Struck R; Brent T P; Ludeman S; Bullock N; Kilborn C; Keir S; Dong Q; Bigner D D; Colvin O M
Modulation of cyclophosphamide activity by O6-alkylguanine-DNA alkyltransferase.
Cancer chemotherapy and pharmacology 1999;43(1):80-5.
1999: Dong Q; Johnson S P; Colvin O M; Bullock N; Kilborn C; Runyon G; Sullivan D M; Easton J; Bigner D D; Nahta R; Marks J; Modrich P; Friedman H S
Multiple DNA repair mechanisms and alkylator resistance in the human medulloblastoma cell line D-283 Med (4-HCR).
Cancer chemotherapy and pharmacology 1999;43(1):73-9.
1998: Friedman H S; McLendon R E; Kerby T; Dugan M; Bigner S H; Henry A J; Ashley D M; Krischer J; Lovell S; Rasheed K; Marchev F; Seman A J; Cokgor I; Rich J; Stewart E; Colvin O M; Provenzale J M; Bigner D D; Haglund M M; Friedman A H; Modrich P L
DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(12):3851-7.
1998: Cokgor I; Friedman A H; Friedman H S
Gliomas.
European journal of cancer (Oxford, England : 1990) 1998;34(12):1910-5; discussion 1916-8.
1998: Friedman H S; Kokkinakis D M; Pluda J; Friedman A H; Cokgor I; Haglund M M; Ashley D M; Rich J; Dolan M E; Pegg A E; Moschel R C; McLendon R E; Kerby T; Herndon J E; Bigner D D; Schold S C
Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(11):3570-5.
1998: Duffner P K; Krischer J P; Horowitz M E; Cohen M E; Burger P C; Friedman H S; Kun L E
Second malignancies in young children with primary brain tumors following treatment with prolonged postoperative chemotherapy and delayed irradiation: a Pediatric Oncology Group study.
Annals of neurology 1998;44(3):313-6.
1998: Burger P C; Yu I T; Tihan T; Friedman H S; Strother D R; Kepner J L; Duffner P K; Kun L E; Perlman E J
Atypical teratoid/rhabdoid tumor of the central nervous system: a highly malignant tumor of infancy and childhood frequently mistaken for medulloblastoma: a Pediatric Oncology Group study.
The American journal of surgical pathology 1998;22(9):1083-92.
1998: Houghton P J; Stewart C F; Thompson J; Santana V M; Furman W L; Friedman H S
Extending principles learned in model systems to clinical trials design.
Oncology (Williston Park, N.Y.) 1998;12(8 Suppl 6):84-93.
1998: Friedman H S; Lovell S; Rasheed K; Friedman A H
Treatment of adults with progressive oligodendroglioma with carboplatin (CBDCA): preliminary results. Writing Committee for The Brain Tumor Center at Duke.
Medical and pediatric oncology 1998;31(1):16-8.
1998: Lee S E; Johnson S P; Hale L P; Li J; Bullock N; Fuchs H; Friedman A; McLendon R; Bigner D D; Modrich P; Friedman H S
Analysis of DNA mismatch repair proteins in human medulloblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(6):1415-9.
1998: Bigner D D; Brown M T; Friedman A H; Coleman R E; Akabani G; Friedman H S; Thorstad W L; McLendon R E; Bigner S H; Zhao X G; Pegram C N; Wikstrand C J; Herndon J E; Vick N A; Paleologos N; Cokgor I; Provenzale J M; Zalutsky M R
Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: phase I trial results.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(6):2202-12.
1998: McLendon R E; Cleveland L; Pegram C; Bigner S H; Bigner D D; Friedman H S
Immunohistochemical detection of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in formalin-fixed, paraffin-embedded astrocytomas.
Laboratory investigation; a journal of technical methods and pathology 1998;78(5):643-4.
1998: Duffner P K; Krischer J P; Sanford R A; Horowitz M E; Burger P C; Cohen M E; Friedman H S; Kun L E
Prognostic factors in infants and very young children with intracranial ependymomas.
Pediatric neurosurgery 1998;28(4):215-22.
1998: McCowage G B; Friedman H S; Moghrabi A; Kerby T; Ferrell L; Stewart E; Duncan-Brown M; Fuchs H E; Tien R; McLendon R E; Meier L; Kurtzberg J; Ashley D; Colvin O M; Longee D C
Activity of high-dose cyclophosphamide in the treatment of childhood malignant gliomas.
Medical and pediatric oncology 1998;30(2):75-80.
1998: Hanley M L; Elion G B; Colvin O M; Modrich P L; Keir S; Adams D J; Bigner D D; Friedman H S
Therapeutic efficacy of vinorelbine against pediatric and adult central nervous system tumors.
Cancer chemotherapy and pharmacology 1998;42(6):479-82.
1998: Coggins C A; Elion G B; Houghton P J; Hare C B; Keir S; Colvin O M; Bigner D D; Friedman H S
Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents.
Cancer chemotherapy and pharmacology 1998;41(6):485-90.
1997: Rasheed B K; Stenzel T T; McLendon R E; Parsons R; Friedman A H; Friedman H S; Bigner D D; Bigner S H
PTEN gene mutations are seen in high-grade but not in low-grade gliomas.
Cancer research 1997;57(19):4187-90.
1997: Bigner S H; McLendon R E; Fuchs H; McKeever P E; Friedman H S
Chromosomal characteristics of childhood brain tumors.
Cancer genetics and cytogenetics 1997;97(2):125-34.
1997: Friedman H S; Johnson S P; Dong Q; Schold S C; Rasheed B K; Bigner S H; Ali-Osman F; Dolan E; Colvin O M; Houghton P; Germain G; Drummond J T; Keir S; Marcelli S; Bigner D D; Modrich P
Methylator resistance mediated by mismatch repair deficiency in a glioblastoma multiforme xenograft.
Cancer research 1997;57(14):2933-6.
1997: Ashley D M; Coleman R E; Fuchs H; Dear G; Ginsberg B; Zalduondo F M; Friedman H S; Longee D
Chronic CSF leak into the peritoneal cavity shown by radionuclide cisternography. Successful treatment with an epidural blood patch.
Clinical nuclear medicine 1997;22(6):390-2.
1997: McLendon R E; Bentley R C; Parisi J E; Tien R D; Harrison J C; Tarbell N J; Billitt A L; Gualtieri R J; Friedman H S
Malignant supratentorial glial-neuronal neoplasms: report of two cases and review of the literature.
Archives of pathology & laboratory medicine 1997;121(5):485-92.
1997: Graham M L; Herndon J E; Casey J R; Chaffee S; Ciocci G H; Krischer J P; Kurtzberg J; Laughlin M J; Longee D C; Olson J F; Paleologus N; Pennington C N; Friedman H S
High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(5):1814-23.
1997: Moghrabi A; Tien R; Fuchs H; Longee D; McLendon R; Friedman H S
False positive images in the follow-up of patients with brain tumors.
Medical and pediatric oncology 1997;28(2):127-31.
1997: Hare C B; Elion G B; Colvin O M; Ali-Osman F; Griffith O W; Petros W P; Keir S; Marcelli S L; Bigner D D; Friedman H S
Characterization of the mechanisms of busulfan resistance in a human glioblastoma multiforme xenograft.
Cancer chemotherapy and pharmacology 1997;40(5):409-14.
1997: Hare C B; Elion G B; Houghton P J; Houghton J A; Keir S; Marcelli S L; Bigner D D; Friedman H S
Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against pediatric and adult central nervous system tumor xenografts.
Cancer chemotherapy and pharmacology 1997;39(3):187-91.
1997: Moynihan K; Elion G B; Pegram C; Reist C J; Wellner D; Bigner D D; Griffith O W; Friedman H S
L-amino acid oxidase (LOX) modulation of melphalan activity against intracranial glioma.
Cancer chemotherapy and pharmacology 1997;39(3):179-86.
1996: Friedman H S; Houghton P J
Treatment of central nervous system xenografts with camptothecins.
Annals of the New York Academy of Sciences 1996;803():210-2.
1996: Jones D N; McCowage G B; Sostman H D; Brizel D M; Layfield L; Charles H C; Dewhirst M W; Prescott D M; Friedman H S; Harrelson J M; Scully S P; Coleman R E
Monitoring of neoadjuvant therapy response of soft-tissue and musculoskeletal sarcoma using fluorine-18-FDG PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(9):1438-44.
1996: Vaidyanathan G; Friedman H S; Keir S T; Zalutsky M R
Evaluation of meta-[211At]astatobenzylguanidine in an athymic mouse human neuroblastoma xenograft model.
Nuclear medicine and biology 1996;23(6):851-6.
1996: Halperin E C; Friedman H S
Is there a correlation between duration of presenting symptoms and stage of medulloblastoma at the time of diagnosis?
Cancer 1996;78(4):874-80.
1996: McCowage G; Tien R; McLendon R; Felsberg G; Fuchs H; Graham M L; Kurtzberg J; Moghrabi A; Ferrell L; Kerby T; Duncan-Brown M; Stewart E; Robertson P L; Colvin O M; Golembe B; Bigner D D; Friedman H S
Successful treatment of childhood pilocytic astrocytomas metastatic to the leptomeninges with high-dose cyclophosphamide.
Medical and pediatric oncology 1996;27(1):32-9.
1996: Brown M T; Coleman R E; Friedman A H; Friedman H S; McLendon R E; Reiman R; Felsberg G J; Tien R D; Bigner S H; Zalutsky M R; Zhao X G; Wikstrand C J; Pegram C N; Herndon J E; Vick N A; Paleologos N; Fredericks R K; Schold S C; Bigner D D
Intrathecal 131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: phase I trial results.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(6):963-72.
1996: Ashley D M; Meier L; Kerby T; Zalduondo F M; Friedman H S; Gajjar A; Kun L; Duffner P K; Smith S; Longee D
Response of recurrent medulloblastoma to low-dose oral etoposide.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(6):1922-7.
1996: Ashley D M; Longee D; Tien R; Fuchs H; Graham M L; Kurtzberg J; Casey J; Olson J; Meier L; Ferrell L; Kerby T; Duncan-Brown M; Stewart E; Colvin O M; Pipas J M; McCowage G; McLendon R; Bigner D D; Friedman H S
Treatment of patients with pineoblastoma with high dose cyclophosphamide.
Medical and pediatric oncology 1996;26(6):387-92.
1996: Duffner P K; Krischer J P; Burger P C; Cohen M E; Backstrom J W; Horowitz M E; Sanford R A; Friedman H S; Kun L E
Treatment of infants with malignant gliomas: the Pediatric Oncology Group experience.
Journal of neuro-oncology 1996;28(2-3):245-56.
1996: Vaidyanathan G; Friedman H S; Keir S T; Zalutsky M R
Localisation of [131I]MIBG in nude mice bearing SK-N-SH human neuroblastoma xenografts: effect of specific activity.
British journal of cancer 1996;73(10):1171-7.
1996: McLendon R E; Fung K M; Bentley R C; Ahmed Rasheed B K; Trojanowski J Q; Bigner S H; Bigner D D; Friedman H S
Production and characterization of two ependymoma xenografts.
Journal of neuropathology and experimental neurology 1996;55(5):540-8.
1996: Broome C B; Schiff R I; Friedman H S
Successful desensitization to carboplatin in patients with systemic hypersensitivity reactions.
Medical and pediatric oncology 1996;26(2):105-10.
1996: Halperin E C; Samulski T; Oakes W J; Friedman H S
Fabrication and testing of a device capable of reducing the incidence of ventricular shunt promoted metastasis.
Journal of neuro-oncology 1996;27(1):39-46.
1996: Moynihan K; Elion G B; Ali-Osman F; Marcelli S; Keir S; Bigner D D; Friedman H S
Enhancement of melphalan activity by inhibition of DNA polymerase-alpha and DNA polymerase-beta.
Cancer chemotherapy and pharmacology 1996;38(4):349-54.
1996: Dong Q; Bullock N; Ali-Osman F; Colvin O M; Bigner D D; Friedman H S
Repair analysis of 4-hydroperoxycyclophosphamide-induced DNA interstrand crosslinking in the c-myc gene in 4-hydroperoxycyclophosphamide-sensitive and -resistant medulloblastoma cell lines.
Cancer chemotherapy and pharmacology 1996;37(3):242-46.
1995: Bigner D D; Archer G E; McLendon R E; Friedman H S; Fuchs H E; Pai L H; Herndon J E; Pastan I H
Efficacy of compartmental administration of immunotoxin LMB-1 (B3-LysPE38) in a rat model of carcinomatous meningitis.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1545-55.
1995: Dong Q; Barsky D; Colvin M E; Melius C F; Ludeman S M; Moravek J F; Colvin O M; Bigner D D; Modrich P; Friedman H S
A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC).
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12170-4.
1995: Lirng J F; Enterline D S; Tien R D; Fuchs H; Friedman H S; Ellington K S; McLendon R P
MRI of papillary meningiomas in children.
Pediatric radiology 1995;25 Suppl 1():S9-13.
1995: Batra S K; Castelino-Prabhu S; Wikstrand C J; Zhu X; Humphrey P A; Friedman H S; Bigner D D
Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(10):1251-9.
1995: Kurpad S N; Friedman H S; Archer G E; McLendon R E; Petros W M; Fuchs H E; Guaspari A; Bigner D D
Intraarterial administration of melphalan for treatment of intracranial human glioma xenografts in athymic rats.
Cancer research 1995;55(17):3803-9.
1995: Friedman H S; Dolan M E; Pegg A E; Marcelli S; Keir S; Catino J J; Bigner D D; Schold S C
Activity of temozolomide in the treatment of central nervous system tumor xenografts.
Cancer research 1995;55(13):2853-7.
1995: Marks L B; Cuthbertson D; Friedman H S
Hematologic toxicity during craniospinal irradiation: the impact of prior chemotherapy.
Medical and pediatric oncology 1995;25(1):45-51.
1995: Duffner P K; Cohen M E; Sanford R A; Horowitz M E; Krischer J P; Burger P C; Friedman H S; Kun L E
Lack of efficacy of postoperative chemotherapy and delayed radiation in very young children with pineoblastoma. Pediatric Oncology Group.
Medical and pediatric oncology 1995;25(1):38-44.
1995: Rasheed B K; McLendon R E; Friedman H S; Friedman A H; Fuchs H E; Bigner D D; Bigner S H
Chromosome 10 deletion mapping in human gliomas: a common deletion region in 10q25.
Oncogene 1995;10(11):2243-6.
1995: Castellino S M; Friedman H S; Elion G B; Ong E T; Marcelli S L; Page R; Bigner D D; Dewhirst M W
Flunarizine enhancement of melphalan activity against drug-sensitive/resistant rhabdomyosarcoma.
British journal of cancer 1995;71(6):1181-7.
1995: Foltz R M; McLendon R E; Friedman H S; Dodge R K; Bigner D D; Dewhirst M W
A pial window model for the intracranial study of human glioma microvascular function.
Neurosurgery 1995;36(5):976-84; discussion 984-5.
1995: Schuster J M; Zalutsky M R; Noska M A; Dodge R; Friedman H S; Bigner D D; Dewhirst M W
Hyperthermic modulation of radiolabelled antibody uptake in a human glioma xenograft and normal tissues.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1995;11(1):59-72.
1995: Moghrabi A; Kerby T; Tien R D; Friedman H S
Prognostic value of contrast-enhanced magnetic resonance imaging in brainstem gliomas.
Pediatric neurosurgery 1995;23(6):293-8.
1995: Strickland D K; Vaidyanathan G; Friedman H S; Zalutsky M R
Meta-[131I]iodobenzylguanidine uptake and meta-[211At]astatobenzylguanidine treatment in human medulloblastoma cell lines.
Journal of neuro-oncology 1995;25(1):9-17.
1995: Batra S K; McLendon R E; Koo J S; Castelino-Prabhu S; Fuchs H E; Krischer J P; Friedman H S; Bigner D D; Bigner S H
Prognostic implications of chromosome 17p deletions in human medulloblastomas.
Journal of neuro-oncology 1995;24(1):39-45.
1995: Bigner D D; Brown M; Coleman R E; Friedman A H; Friedman H S; McLendon R E; Bigner S H; Zhao X G; Wikstrand C J; Pegram C N
Phase I studies of treatment of malignant gliomas and neoplastic meningitis with 131I-radiolabeled monoclonal antibodies anti-tenascin 81C6 and anti-chondroitin proteoglycan sulfate Me1-14 F (ab')2--a preliminary report.
Journal of neuro-oncology 1995;24(1):109-22.
1995: Friedman H S; Bigner S H; Bigner D D
Cyclophosphamide therapy of medulloblastoma: from the laboratory to the clinic and back again (and again and again).
Journal of neuro-oncology 1995;24(1):103-8.
1994: Dolan M E; Chae M Y; Pegg A E; Mullen J H; Friedman H S; Moschel R C
Metabolism of O6-benzylguanine, an inactivator of O6-alkylguanine-DNA alkyltransferase.
Cancer research 1994;54(19):5123-30.
1994: Friedman H S; Archer G E; McLendon R E; Schuster J M; Colvin O M; Guaspari A; Blum R; Savina P A; Fuchs H E; Bigner D D
Intrathecal melphalan therapy of human neoplastic meningitis in athymic nude rats.
Cancer research 1994;54(17):4710-4.
1994: Osumi A K; Mclendon R E; Tien R D; Friedman H S; Graham M; Hockenberger B; Halperin E C; Oakes W J
Well differentiated astrocytoma occurring nine years after radiation therapy for medulloblastoma.
Clinical neuropathology 1994;13(5):281-5.
1994: Friedman H S; Dolan M E; Kaufmann S H; Colvin O M; Griffith O W; Moschel R C; Schold S C; Bigner D D; Ali-Osman F
Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan.
Cancer research 1994;54(13):3487-93.
1994: Rasheed B K; McLendon R E; Herndon J E; Friedman H S; Friedman A H; Bigner D D; Bigner S H
Alterations of the TP53 gene in human gliomas.
Cancer research 1994;54(5):1324-30.
1994: Moghrabi A; Friedman H S; McLendon R; Hockenberger B; Tien R D; Halperin E C; Oakes W J
Arteriovenous malformation mimicking recurrent medulloblastoma.
Medical and pediatric oncology 1994;22(2):140-3.
1994: Friedman H S; Houghton P J; Schold S C; Keir S; Bigner D D
Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts.
Cancer chemotherapy and pharmacology 1994;34(2):171-4.
1994: Bruggers C S; Friedman H S; Tien R; Delong R
Cerebral atrophy in an infant following treatment with ifosfamide.
Medical and pediatric oncology 1994;23(4):380-3.
1994: Aaron R H; Elion G B; Colvin O M; Graham M; Keir S; Bigner D D; Friedman H S
Busulfan therapy of central nervous system xenografts in athymic mice.
Cancer chemotherapy and pharmacology 1994;35(2):127-31.
1994: Dolan M E; Pegg A E; Moschel R C; Vishnuvajjala B R; Flora K P; Grever M R; Friedman H S
Biodistribution of O6-benzylguanine and its effectiveness against human brain tumor xenografts when given in polyethylene glycol or cremophor-EL.
Cancer chemotherapy and pharmacology 1994;35(2):121-6.
1994: Nashold J R; Oakes W J; Friedman H S; Halperin E C; Soo M; Hockenberger B; Fuller G N; Tien R
Management of pineal non-germinoma germ cell tumor with residual teratoma and normal alpha-fetoprotein.
Medical and pediatric oncology 1994;22(2):137-9.
1993: Garg S; Garg P K; Zhao X G; Friedman H S; Bigner D D; Zalutsky M R
Radioiodination of a monoclonal antibody using N-succinimidyl 5-iodo-3-pyridinecarboxylate.
Nuclear medicine and biology 1993;20(7):835-42.
1993: Halperin E C; Friedman H S; Schold S C; Fuchs H E; Oakes W J; Hockenberger B; Burger P C
Surgery, hyperfractionated craniospinal irradiation, and adjuvant chemotherapy in the management of supratentorial embryonal neuroepithelial neoplasms in children.
Surgical neurology 1993;40(4):278-83.
1993: Nelson S C; Bruggers C S; Kurtzberg J; Friedman H S
Management of leukemic hyperleukocytosis with hydration, urinary alkalinization, and allopurinol. Are cranial irradiation and invasive cytoreduction necessary?
The American journal of pediatric hematology/oncology 1993;15(3):351-5.
1993: Strong J A; Hatten H P; Brown M T; Debatin J F; Friedman H S; Oakes W J; Tien R
Pilocytic astrocytoma: correlation between the initial imaging features and clinical aggressiveness.
AJR. American journal of roentgenology 1993;161(2):369-72.
1993: Moghrabi A; Friedman H S; Burger P C; Tien R; Oakes W J
Carboplatin treatment of progressive optic pathway gliomas to delay radiotherapy.
Journal of neurosurgery 1993;79(2):223-7.
1993: Duffner P K; Horowitz M E; Krischer J P; Friedman H S; Burger P C; Cohen M E; Sanford R A; Mulhern R K; James H E; Freeman C R
Postoperative chemotherapy and delayed radiation in children less than three years of age with malignant brain tumors.
The New England journal of medicine 1993;328(24):1725-31.
1993: Furie D M; Felsberg G J; Tien R D; Friedman H S; Fuchs H; McLendon R
MRI of gangliocytoma of cerebellum and spinal cord.
Journal of computer assisted tomography 1993;17(3):488-91.
1993: Brown M T; Friedman H S; Oakes W J; Boyko O B; Hockenberger B; Schold S C
Chemotherapy for pilocytic astrocytomas.
Cancer 1993;71(10):3165-72.
1993: Schuster J M; Friedman H S; Archer G E; Fuchs H E; McLendon R E; Colvin O M; Bigner D D
Intraarterial therapy of human glioma xenografts in athymic rats using 4-hydroperoxycyclophosphamide.
Cancer research 1993;53(10 Suppl):2338-43.
1993: Ashdown B C; Boyko O B; Uglietta J P; Friedman H S; Hockenberger B; Oakes W J; Fuller G N
Postradiation cerebellar necrosis mimicking tumor: MR appearance.
Journal of computer assisted tomography 1993;17(1):124-6.
1993: Wikstrand C J; Longee D C; McLendon R E; Fuller G N; Friedman H S; Fredman P; Svennerholm L; Bigner D D
Lactotetraose series ganglioside 3',6'-isoLD1 in tumors of central nervous and other systems in vitro and in vivo.
Cancer research 1993;53(1):120-6.
1993: Nelson S C; Friedman H S; Hockenberger B; Vandersteenhoven J J; Gray L; Touri S L; Oakes W J
False-positive MRI detection of recurrent or metastatic pediatric infratentorial tumors.
Medical and pediatric oncology 1993;21(5):350-5.
1993: Bruggers C S; Friedman H S; Fuller G N; Tien R D; Marks L B; Halperin E C; Hockenberger B; Oakes W J; Hoffman J M
Comparison of serial PET and MRI scans in a pediatric patient with a brainstem glioma.
Medical and pediatric oncology 1993;21(4):301-6.
1993: Castellino S; Elion G B; Griffith O W; Dewhirst M; Kurtzberg J; Cattley R C; Scott P; Bigner D D; Friedman H S
Development of a model of melphalan-induced gastrointestinal toxicity in mice.
Cancer chemotherapy and pharmacology 1993;31(5):376-80.
1993: Felker G M; Friedman H S; Dolan M E; Moschel R C; Schold C
Treatment of subcutaneous and intracranial brain tumor xenografts with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.
Cancer chemotherapy and pharmacology 1993;32(6):471-6.
1992: Friedman H S; Dolan M E; Moschel R C; Pegg A E; Felker G M; Rich J; Bigner D D; Schold S C
Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme.
Journal of the National Cancer Institute 1992;84(24):1926-31.
1992: Donnal J; Halperin E C; Friedman H S; Boyko O B
Subfrontal recurrence of medulloblastoma.
AJNR. American journal of neuroradiology 1992;13(6):1617-8.
1992: Mulligan K; Nelson S; Friedman H S; Andrews P I
Shigellosis-associated encephalopathy.
The Pediatric infectious disease journal 1992;11(10):889-90.
1992: Malik R K; Fuller G N; Oakes W J; Tien R; Hockenberger B; Friedman H S; Halperin E C
Back pain and paraplegia in a fifteen-year-old boy.
The Journal of pediatrics 1992;121(4):652-8.
1992: Friedman H S; Colvin O M; Kaufmann S H; Ludeman S M; Bullock N; Bigner D D; Griffith O W
Cyclophosphamide resistance in medulloblastoma.
Cancer research 1992;52(19):5373-8.
1992: Nelson S C; Friedman H S; Oakes W J; Halperin E C; Tien R; Fuller G N; Hockenberger B; Scroggs M W; Moncino M; Kurtzberg J
Successful therapy for trilateral retinoblastoma.
American journal of ophthalmology 1992;114(1):23-9.
1992: Friedman H S; Oakes W J
New therapeutic options in the management of childhood brain tumors.
Oncology (Williston Park, N.Y.) 1992;6(5):27-36; discussion 36, 39-40.
1992: He X M; Ostrowski L E; von Wronski M A; Friedman H S; Wikstrand C J; Bigner S H; Rasheed A; Batra S K; Mitra S; Brent T P
Expression of O6-methylguanine-DNA methyltransferase in six human medulloblastoma cell lines.
Cancer research 1992;52(5):1144-8.
1992: Laskowitz D T; Elion G B; Dewhirst M W; Griffith O W; Casero R A; Scott P A; Bullock N; Bigner D D; Friedman H S
Effects of glutathione or polyamine depletion on in vivo thermosensitization.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1992;8(2):199-208.
1992: Laskowitz D T; Elion G B; Dewhirst M W; Griffith O W; Savina P M; Blum M R; Prescott D M; Bigner D D; Friedman H S
Hyperthermia-induced enhancement of melphalan activity against a melphalan-resistant human rhabdomyosarcoma xenograft.
Radiation research 1992;129(2):218-23.
1992: Friedman H S; Krischer J P; Burger P; Oakes W J; Hockenberger B; Weiner M D; Falletta J M; Norris D; Ragab A H; Mahoney D H
Treatment of children with progressive or recurrent brain tumors with carboplatin or iproplatin: a Pediatric Oncology Group randomized phase II study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(2):249-56.
1992: Hoffman J M; Hanson M W; Friedman H S; Hockenberger B M; Oakes W J; Halperin E C; Coleman R E
FDG-PET in pediatric posterior fossa brain tumors.
Journal of computer assisted tomography 1992;16(1):62-8.
1992: Laskowitz D T; Elion G B; Dewhirst M W; Griffith O W; Cattley R C; Bigner D D; Friedman H S
Enhancement of melphalan-induced gastrointestinal toxicity in mice treated with regional hyperthermia and BSO-mediated glutathione depletion.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1992;8(1):111-20.
1992: Halperin E C; Brizel D M; Honore G; Sontag M R; Griffith O W; Bigner D D; Friedman H S
The radiation dose-response relationship in a human glioma xenograft and an evaluation of the influence of glutathione depletion by buthionine sulfoximine.
International journal of radiation oncology, biology, physics 1992;24(1):103-9.
1992: Debatin J F; Nadel S N; Gray L; Friedman H S; Trotter P; Hockenberger B; Oakes W J
Phase III clinical evaluation of gadoteridol injection: experience in pediatric neuro-oncologic MR imaging.
Pediatric radiology 1992;22(2):93-8.
1992: Marks L B; Friedman H S; Kurtzberg J; Oakes W J; Hockenberger B M
Reversal of radiation-induced neutropenia by granulocyte colony-stimulating factor.
Medical and pediatric oncology 1992;20(3):240-2.
1991: Friedman H S; Tuori S L; Hatten H P; Hockenberger B; Vandersteenhoven J J; Oakes W J
Inflammatory lesion mimicking a metastatic ependymoma.
Neurosurgery 1991;29(4):617-20.
1991: Friedman H S; Oakes W J; Bigner S H; Wikstrand C J; Bigner D D
Medulloblastoma: tumor biological and clinical perspectives.
Journal of neuro-oncology 1991;11(1):1-15.
1991: Lilley E R; Elion G B; Dewhirst M W; Schold S C; Blum M R; Savina P M; Laskowitz D T; Bigner D D; Friedman H S
Therapeutic analysis of melphalan-resistant human rhabdomyosarcoma xenograft TE-671 MR.
Cancer research 1991;51(15):3906-9.
1991: Humphrey P A; Gangarosa L M; Wong A J; Archer G E; Lund-Johansen M; Bjerkvig R; Laerum O D; Friedman H S; Bigner D D
Deletion-mutant epidermal growth factor receptor in human gliomas: effects of type II mutation on receptor function.
Biochemical and biophysical research communications 1991;178(3):1413-20.
1991: Bruggers C S; Friedman H S; Phillips P C; Wiener M D; Hockenberger B; Oakes W J; Buckley E G
Leptomeningeal dissemination of optic pathway gliomas in three children.
American journal of ophthalmology 1991;111(6):719-23.
1991: He X M; Wikstrand C J; Friedman H S; Bigner S H; Pleasure S; Trojanowski J Q; Bigner D D
Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts.
Laboratory investigation; a journal of technical methods and pathology 1991;64(6):833-43.
1991: Schuster J M; Friedman H S; Bigner D D
Therapeutic analysis of in vitro and in vivo brain tumor models.
Neurologic clinics 1991;9(2):375-82.
1991: Brown M T; Friedman H S; Oakes W J; Boyko O B; Schold S C
Sagittal sinus thrombosis and leptomeningeal medulloblastoma.
Neurology 1991;41(3):455-6.
1991: Rhodes R E; Friedman H S; Hatten H P; Hockenberger B; Oakes W J; Tomita T
Contrast-enhanced MR imaging of neurocutaneous melanosis.
AJNR. American journal of neuroradiology 1991;12(2):380-2.
1991: Longee D C; Friedman H S; Phillips P C; Burger P C; Oakes W J; Heffez D; Wharam M; Strauss L; Fuller G N; Schold S C
Osteoblastic metastases from astrocytomas: a report of two cases.
Medical and pediatric oncology 1991;19(4):318-24.
1991: Wang A M; Elion G B; Friedman H S; Bodell W J; Bigner D D; Schold S C
Positive therapeutic interaction between thiopurines and alkylating drugs in human glioma xenografts.
Cancer chemotherapy and pharmacology 1991;27(4):278-84.
1991: Griebel M; Friedman H S; Halperin E C; Wiener M D; Marks L; Oakes W J; Hoffman J M; DeLong G R; Schold S C; Hockenberger B
Reversible neurotoxicity following hyperfractionated radiation therapy of brain stem glioma.
Medical and pediatric oncology 1991;19(3):182-6.
1991: Wikstrand C J; Friedman H S; Bigner D D
Medulloblastoma cell-substrate interaction in vitro.
Invasion & metastasis 1991;11(6):310-24.
1991: Bruggers C S; Kurtzberg J; Friedman H S
Vincristine therapy for severe platelet alloimmunization.
The American journal of pediatric hematology/oncology 1991;13(3):300-4.
1990: Bigner S H; Humphrey P A; Wong A J; Vogelstein B; Mark J; Friedman H S; Bigner D D
Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts.
Cancer research 1990;50(24):8017-22.
1990: Wiener M D; Boyko O B; Friedman H S; Hockenberger B; Oakes W J
False-positive spinal MR findings for subarachnoid spread of primary CNS tumor in postoperative pediatric patients.
AJNR. American journal of neuroradiology 1990;11(6):1100-3.
1990: Fishbein J D; Friedman H S; Bennett B B; Falletta J M
Catheter-related sepsis refractory to antibiotics treated successfully with adjunctive urokinase infusion.
The Pediatric infectious disease journal 1990;9(9):676-8.
1990: Rippe D J; Boyko O B; Fuller G N; Friedman H S; Oakes W J; Schold S C
Gadopentetate-dimeglumine-enhanced MR imaging of gliomatosis cerebri: appearance mimicking leptomeningeal tumor dissemination.
AJNR. American journal of neuroradiology 1990;11(4):800-1.
1990: Humphrey P A; Wong A J; Vogelstein B; Zalutsky M R; Fuller G N; Archer G E; Friedman H S; Kwatra M M; Bigner S H; Bigner D D
Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4207-11.
1990: Oakes W J; Friedman H S; Bigner S H; Bullock N H; Bigner D D
Successful laboratory growth and analysis of CUSA-obtained medulloblastoma samples. Technical note.
Journal of neurosurgery 1990;72(5):821-3.
1990: Longee D C; Friedman H S; Albright R E; Burger P C; Oakes W J; Moore J O; Schold S C
Treatment of patients with recurrent gliomas with cyclophosphamide and vincristine.
Journal of neurosurgery 1990;72(4):583-8.
1990: Friedman H S; Colvin O M; Aisaka K; Popp J; Bossen E H; Reimer K A; Powell J B; Hilton J; Gross S S; Levi R
Glutathione protects cardiac and skeletal muscle from cyclophosphamide-induced toxicity.
Cancer research 1990;50(8):2455-62.
1990: Bigner S H; Friedman H S; Vogelstein B; Oakes W J; Bigner D D
Amplification of the c-myc gene in human medulloblastoma cell lines and xenografts.
Cancer research 1990;50(8):2347-50.
1990: Colapinto E V; Zalutsky M R; Archer G E; Noska M A; Friedman H S; Carrel S; Bigner D D
Radioimmunotherapy of intracerebral human glioma xenografts with 131I-labeled F(ab')2 fragments of monoclonal antibody Mel-14.
Cancer research 1990;50(6):1822-7.
1990: Cope D A; Dewhirst M W; Friedman H S; Bigner D D; Zalutsky M R
Enhanced delivery of a monoclonal antibody F(ab')2 fragment to subcutaneous human glioma xenografts using local hyperthermia.
Cancer research 1990;50(6):1803-9.
1990: Fuchs H E; Archer G E; Colvin O M; Bigner S H; Schuster J M; Fuller G N; Muhlbaier L H; Schold S C; Friedman H S; Bigner D D
Activity of intrathecal 4-hydroperoxycyclophosphamide in a nude rat model of human neoplastic meningitis.
Cancer research 1990;50(6):1954-9.
1990: Rippe D J; Boyko O B; Friedman H S; Oakes W J; Schold S C; DeLong G R; Meisler W J
Gd-DTPA-enhanced MR imaging of leptomeningeal spread of primary intracranial CNS tumor in children.
AJNR. American journal of neuroradiology 1990;11(2):329-32.
1990: Lippitz B E; Halperin E C; Griffith O W; Colvin O M; Honore G; Ostertag C B; Bigner D D; Friedman H S
L-buthionine-sulfoximine-mediated radiosensitization in experimental interstitial radiotherapy of intracerebral D-54 MG glioma xenografts in athymic mice.
Neurosurgery 1990;26(2):255-60.
1990: Lilley E R; Rosenberg M C; Elion G B; Colvin O M; Bigner D D; Friedman H S
Synergistic interactions between cyclophosphamide or melphalan and VP-16 in a human rhabdomyosarcoma xenograft.
Cancer research 1990;50(2):284-7.
1990: Moncino M D; Friedman H S; Kurtzberg J; Pizzo S V
Papillary adenocarcinoma of the renal pelvis in a child: case report and brief review of the literature.
Medical and pediatric oncology 1990;18(1):81-6.
1990: Ware R; Friedman H S; Kinney T R; Kurtzberg J; Chaffee S; Falletta J M
Familial erythrophagocytic lymphohistiocytosis: late relapse despite continuous high-dose VP-16 chemotherapy.
Medical and pediatric oncology 1990;18(1):27-9.
1989: Rosenberg M C; Colvin O M; Griffith O W; Bigner S H; Elion G B; Horton J K; Lilley E; Bigner D D; Friedman H S
Establishment of a melphalan-resistant rhabdomyosarcoma xenograft with cross-resistance to vincristine and enhanced sensitivity following buthionine sulfoximine-mediated glutathione depletion.
Cancer research 1989;49(24 Pt 1):6917-22.
1989: Friedman H S; Kurtzberg J; Schold S C; Oakes W J
Cerebrospinal fluid protein elevation secondary to a subdural fluid collection in a child receiving multiple lumbar punctures.
The Journal of pediatrics 1989;115(3):439-41.
1989: Zalutsky M R; Garg P K; Friedman H S; Bigner D D
Labeling monoclonal antibodies and F(ab')2 fragments with the alpha-particle-emitting nuclide astatine-211: preservation of immunoreactivity and in vivo localizing capacity.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(18):7149-53.
1989: Bigner S H; Schold S C; Friedman H S; Mark J; Bigner D D
Chromosomal composition of malignant human gliomas through serial subcutaneous transplantation in athymic mice.
Cancer genetics and cytogenetics 1989;40(1):111-20.
1989: Friedman H S; Schold S C; Mahaley M S; Colvin O M; Oakes W J; Vick N A; Burger P C; Bigner S H; Borowitz M; Halperin E C
Phase II treatment of medulloblastoma and pineoblastoma with melphalan: clinical therapy based on experimental models of human medulloblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(7):904-11.
1989: Stine K C; Friedman H S; Kurtzberg J; Filston H C; Baker M E; Lowe J; Falletta J M
Pulmonary septic emboli mimicking metastatic rhabdomyosarcoma.
Journal of pediatric surgery 1989;24(5):491-3.
1989: Schold S C; Brent T P; von Hofe E; Friedman H S; Mitra S; Bigner D D; Swenberg J A; Kleihues P
O6-alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts.
Journal of neurosurgery 1989;70(4):573-7.
1989: Friedman H S; Colvin O M; Griffith O W; Lippitz B; Elion G B; Schold S C; Hilton J; Bigner D D
Increased melphalan activity in intracranial human medulloblastoma and glioma xenografts following buthionine sulfoximine-mediated glutathione depletion.
Journal of the National Cancer Institute 1989;81(7):524-7.
1989: Friedman H S; Schold S C; Djang W T; Kurtzberg J; Longee D C; Halperin E C; Falletta J M; Coleman R E; Oakes W J
Criteria for termination of phase II chemotherapy for patients with progressive or recurrent brain tumor.
Neurology 1989;39(1):62-6.
1989: He X M; Skapek S X; Wikstrand C J; Friedman H S; Trojanowski J Q; Kemshead J T; Coakham H B; Bigner S H; Bigner D D
Phenotypic analysis of four human medulloblastoma cell lines and transplantable xenografts.
Journal of neuropathology and experimental neurology 1989;48(1):48-68.
1989: Halperin E C; Wehn S M; Scott J W; Djang W; Oakes W J; Friedman H S
Selection of a management strategy for pediatric brainstem tumors.
Medical and pediatric oncology 1989;17(2):117-26.
1988: Skapek S X; Colvin O M; Griffith O W; Groothuis D R; Colapinto E V; Lee Y; Hilton J; Elion G B; Bigner D D; Friedman H S
Buthionine sulfoximine-mediated depletion of glutathione in intracranial human glioma-derived xenografts.
Biochemical pharmacology 1988;37(22):4313-7.
1988: Friedman H S; Skapek S X; Colvin O M; Elion G B; Blum M R; Savina P M; Hilton J; Schold S C; Kurtzberg J; Bigner D D
Melphalan transport, glutathione levels, and glutathione-S-transferase activity in human medulloblastoma.
Cancer research 1988;48(19):5397-402.
1988: Colapinto E V; Humphrey P A; Zalutsky M R; Groothuis D R; Friedman H S; de Tribolet N; Carrel S; Bigner D D
Comparative localization of murine monoclonal antibody Me1-14 F(ab')2 fragment and whole IgG2a in human glioma xenografts.
Cancer research 1988;48(20):5701-7.
1988: Friedman H S; Colvin O M; Skapek S X; Ludeman S M; Elion G B; Schold S C; Jacobsen P F; Muhlbaier L H; Bigner D D
Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents.
Cancer research 1988;48(15):4189-95.
1988: Ware R; Friedman H S; Gutman L T; Rourk M H; Shorter N A; Filston H C
Combined medical and surgical management of severe pseudomembranous colitis.
The Pediatric infectious disease journal 1988;7(8):602-4.
1988: Longee D C; Friedman H S; Djang W T; Halperin E; Schold S C; Oakes W J
Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials.
Neurosurgery 1988;23(2):248-53.
1988: Ware R; Kurtzberg J; Friedman H S; Falletta J M; Kinney T R
Chronic immune-mediated thrombocytopenia after varicella infection.
The Journal of pediatrics 1988;112(5):742-4.
1988: Skapek S X; Colvin O M; Griffith O W; Elion G B; Bigner D D; Friedman H S
Enhanced melphalan cytotoxicity following buthionine sulfoximine-mediated glutathione depletion in a human medulloblastoma xenograft in athymic mice.
Cancer research 1988;48(10):2764-7.
1988: Lee Y; Bullard D E; Humphrey P A; Colapinto E V; Friedman H S; Zalutsky M R; Coleman R E; Bigner D D
Treatment of intracranial human glioma xenografts with 131I-labeled anti-tenascin monoclonal antibody 81C6.
Cancer research 1988;48(10):2904-10.
1988: Humphrey P A; Wong A J; Vogelstein B; Friedman H S; Werner M H; Bigner D D; Bigner S H
Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts.
Cancer research 1988;48(8):2231-8.
1988: Friedman H S; Burger P C; Bigner S H; Trojanowski J Q; Brodeur G M; He X M; Wikstrand C J; Kurtzberg J; Berens M E; Halperin E C
Phenotypic and genotypic analysis of a human medulloblastoma cell line and transplantable xenograft (D341 Med) demonstrating amplification of c-myc.
The American journal of pathology 1988;130(3):472-84.
1988: Lee Y S; Bullard D E; Zalutsky M R; Coleman R E; Wikstrand C J; Friedman H S; Colapinto E V; Bigner D D
Therapeutic efficacy of antiglioma mesenchymal extracellular matrix 131I-radiolabeled murine monoclonal antibody in a human glioma xenograft model.
Cancer research 1988;48(3):559-66.
1988: Bigner S H; Mark J; Friedman H S; Biegel J A; Bigner D D
Structural chromosomal abnormalities in human medulloblastoma.
Cancer genetics and cytogenetics 1988;30(1):91-101.
1988: Ware R; Friedman H S; Filston H C; Chaffee S; Kurtzberg J; Kinney T R; Falletta J M
Childhood hepatic mesenchymoma: successful treatment with surgery and multiple-agent chemotherapy.
Medical and pediatric oncology 1988;16(1):62-5.
1988: Colapinto E V; Lee Y S; Humphrey P A; Zalutsky M R; Friedman H S; Bullard D E; Bigner D D
The localisation of radiolabelled murine monoclonal antibody 81C6 and its Fab fragment in human glioma xenografts in athymic mice.
British journal of neurosurgery 1988;2(2):179-91.
1987: Kurtzberg J; Friedman H S; Chaffee S; Falletta J M; Kinney T R; Kurlander R; Matthews T J; Schwartz R S
Efficacy of intravenous gamma globulin in autoimmune-mediated pediatric blood dyscrasias.
The American journal of medicine 1987;83(4A):4-9.
1987: Kurtzberg J; Friedman H S; Kinney T R; Chaffee S; Falletta J M
Treatment of platelet alloimmunization with intravenous immunoglobulin. Two case reports and review of the literature.
The American journal of medicine 1987;83(4A):30-3.
1987: Schold S C; Mahaley M S; Vick N A; Friedman H S; Burger P C; DeLong E R; Albright R E; Bullard D E; Khandekar J D; Cairncross J G
Phase II diaziquone-based chemotherapy trials in patients with anaplastic supratentorial astrocytic neoplasms.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1987;5(3):464-71.
1987: Friedman H S; Oakes W J
The chemotherapy of posterior fossa tumors in childhood.
Journal of neuro-oncology 1987;5(3):217-29.
1987: Becton D L; Friedman H S; Armstrong B E; Kurtzburg J; Chaffee S; Falletta J M; Kinney T R
Bacterial endocarditis in a child with a Broviac catheter.
Pediatric hematology and oncology 1987;4(2):131-6.
1987: Becton D L; Kurtzberg J; Kinney T R; Friedman H S; Chaffee S; Falletta J M
Treatment of lymphohistiocytic erythrophagocytosis with VP-16 and aziridinylbenzoquinone.
Medical and pediatric oncology 1987;15(2):58-61.
1987: Kurtzberg J; Friedman H S; Kinney T R; Chaffee S; Stine K; Falletta J M; Weinhold K J
Management of human immunodeficiency virus-associated thrombocytopenia with intravenous gamma globulin.
The American journal of pediatric hematology/oncology 1987;9(4):299-301.
1986: Malik R K; Friedman H S; Djang W T; Falletta J M; Buckley E; Kurtzberg J; Kinney T R; Stine K; Chaffee S; Hayes J
Treatment of trilateral retinoblastoma with vincristine and cyclophosphamide.
American journal of ophthalmology 1986;102(5):650-6.
1986: Bigner S H; Friedman H S; Kinney T R; Kurtzberg J; Chaffee S; Becton D; Falletta J M
9p- in a girl with acute lymphocytic leukemia and sickle cell disease.
Cancer genetics and cytogenetics 1986;21(3):267-9.
1986: Friedman H S; Mahaley M S; Schold S C; Vick N A; Falletta J M; Bullard D E; D'Souza B J; Khandekar J D; Lew S; Oakes W J
Efficacy of vincristine and cyclophosphamide in the therapy of recurrent medulloblastoma.
Neurosurgery 1986;18(3):335-40.
1986: Ware R; Kinney T R; Friedman H S; Falletta J M; Rosse W F
Prognostic implications for direct platelet-associated IgG in childhood idiopathic thrombocytopenic purpura.
The American journal of pediatric hematology/oncology 1986;8(1):32-7.
1986: Becton D L; Friedman H S; Kurtzberg J; Chaffee S; Falletta J M; Kinney T R
Severe Mycoplasma pneumonia in three sisters with sickle cell disease.
Pediatric hematology and oncology 1986;3(3):259-65.
1984: Becton D L; Kinney T R; Chaffee S; Kurtzberg J; Friedman H S; Falleta J M
High-dose intravenous immunoglobulin for severe platelet alloimmunization.
Pediatrics 1984;74(6):1120-3.
1984: Becton D L; Chaffee S; Friedman H S; Kurtzberg J; Kinney T R; Falletta J M
Frequency of bone marrow aspirates in leukemia.
The Journal of pediatrics 1984;105(3):509-10.

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