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Peter Friedrich

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Zoltán Bozóky; Gergely Róna; Katalin F Medzihradszky; Gábor Merényi; Beáta G Vértessy; Eva Klement; Peter Friedrich
Calpain-catalyzed proteolysis of human dUTPase specifically removes the nuclear localization signal peptide.
László Kovács; Anita Alexa; Eva Klement; Endre Kókai; Agnes Tantos; Gergö Gógl; Tamás Sperka; Katalin F Medzihradszky; József Tözsér; Viktor Dombrádi; Peter Friedrich
Regulation of calpain B from Drosophila melanogaster by phosphorylation.
Orsolya Toke; Zoltán Bánóczi; Gábor Tárkányi; Peter Friedrich; Ferenc Hudecz
Folding transitions in calpain activator peptides studied by solution NMR spectroscopy.

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All Publications

2011: Zoltán Bozóky; Gergely Róna; Katalin F Medzihradszky; Gábor Merényi; Beáta G Vértessy; Eva Klement; Peter Friedrich
Calpain-catalyzed proteolysis of human dUTPase specifically removes the nuclear localization signal peptide.
PloS one 2011;6(5):e19546.
2009: László Kovács; Anita Alexa; Eva Klement; Endre Kókai; Agnes Tantos; Gergö Gógl; Tamás Sperka; Katalin F Medzihradszky; József Tözsér; Viktor Dombrádi; Peter Friedrich
Regulation of calpain B from Drosophila melanogaster by phosphorylation.
The FEBS journal 2009;276(17):4959-72.
2009: Orsolya Toke; Zoltán Bánóczi; Gábor Tárkányi; Peter Friedrich; Ferenc Hudecz
Folding transitions in calpain activator peptides studied by solution NMR spectroscopy.
Journal of peptide science : an official publication of the European Peptide Society 2009;15(6):404-10.
2009: Agnes Tantos; Peter Friedrich; Peter Tompa
Cold stability of intrinsically disordered proteins.
FEBS letters 2009;583(2):465-9.
2009: Zoltan Bozoky; Anita Alexa; Julia Dancsok; Gergo Gogl; Eva Klement; Katalin F Medzihradszky; Peter Friedrich
Identifying calpain substrates in intact S2 cells of Drosophila.
Archives of biochemistry and biophysics 2009;481(2):219-25.
2008: Ildikó Világi; Dávid Sándor Kiss; Attila Farkas; Sándor Borbély; Krisztián Tárnok; Katalin Halasy; Zoltán Bánóczi; Ferenc Hudecz; Peter Friedrich
Synthetic calpain activator boosts neuronal excitability without extra Ca2+.
Molecular and cellular neurosciences 2008;38(4):629-36.
2008: Zoltán Bánóczi; Anita Alexa; Attila Farkas; Peter Friedrich; Ferenc Hudecz
Novel cell-penetrating calpain substrate.
Bioconjugate chemistry 2008;19(7):1375-81.
2007: Zoltan Banóczi; Agnes Tantos; Attila Farkas; Peter Tompa; Peter Friedrich; Ferenc Hudecz
Synthesis of cell-penetrating conjugates of calpain activator peptides.
Bioconjugate chemistry 2007;18(1):130-7.
2006: Endre Kókai; Agnes Tantos; Emese Vissi; Balázs Szöőr; Peter Tompa; János Gausz; Luke Alphey; Peter Friedrich; Viktor Dombrádi
CG15031/PPYR1 is an intrinsically unstructured protein that interacts with protein phosphatase Y.
Archives of biochemistry and biophysics 2006;451(1):59-67.
2006: Veronika Csizmók; Edit Szollosi; Peter Friedrich; Peter Tompa
A novel two-dimensional electrophoresis technique for the identification of intrinsically unstructured proteins.
Molecular & cellular proteomics : MCP 2006;5(2):265-73.
2005: Peter Friedrich; Zoltán Bozóky
Digestive versus regulatory proteases: on calpain action in vivo.
Biological chemistry 2005;386(7):609-12.
2005: Zoltán Bozóky; Anita Alexa; Peter Tompa; Peter Friedrich
Multiple interactions of the 'transducer' govern its function in calpain activation by Ca2+.
The Biochemical journal 2005;388(Pt 3):741-4.
2005: Veronika Csizmók; Monika Bokor; Péter Bánki; Eva Klement; Katalin F Medzihradszky; Peter Friedrich; Kálmán Tompa; Peter Tompa
Primary contact sites in intrinsically unstructured proteins: the case of calpastatin and microtubule-associated protein 2.
Biochemistry 2005;44(10):3955-64.
2005: Monika Bokor; Veronika Csizmók; Dénes Kovács; Péter Bánki; Peter Friedrich; Peter Tompa; Kálmán Tompa
NMR relaxation studies on the hydrate layer of intrinsically unstructured proteins.
Biophysical journal 2005;88(3):2030-7.
2005: Ildikó Világi; György Bárdos; K Dénes; Beatrix Farkas; Peter Friedrich
Enhancement of synaptic strength in the somatosensory cortex following nerve injury does not parallel behavioural alterations.
Brain research bulletin 2005;64(6):463-9.
2004: Peter Friedrich
The intriguing Ca2+ requirement of calpain activation.
Biochemical and biophysical research communications 2004;323(4):1131-3.
2004: Beatrix Farkas; Agnes Tantos; Katalin Schlett; Ildikó Világi; Peter Friedrich
Ischemia-induced increase in long-term potentiation is warded off by specific calpain inhibitor PD150606.
Brain research 2004;1024(1-2):150-8.
2004: Peter Friedrich; Peter Tompa; Attila Farkas
The calpain-system of Drosophila melanogaster: coming of age.
BioEssays : news and reviews in molecular, cellular and developmental biology 2004;26(10):1088-96.
2004: Attila Farkas; Gábor Nardai; Péter Csermely; Peter Tompa; Peter Friedrich
DUK114, the Drosophila orthologue of bovine brain calpain activator protein, is a molecular chaperone.
The Biochemical journal 2004;383(Pt 1):165-70.
2004: Monika Fuxreiter; Istvan Simon; Peter Friedrich; Peter Tompa
Preformed structural elements feature in partner recognition by intrinsically unstructured proteins.
Journal of molecular biology 2004;338(5):1015-26.
2004: Peter Tompa; Peter Buzder-Lantos; Agnes Tantos; Attila Farkas; András Szilágyi; Zoltán Bánóczi; Ferenc Hudecz; Peter Friedrich
On the sequential determinants of calpain cleavage.
The Journal of biological chemistry 2004;279(20):20775-85.
2004: Anita Alexa; Zoltán Bozóky; Attila Farkas; Peter Tompa; Peter Friedrich
Contribution of distinct structural elements to activation of calpain by Ca2+ ions.
The Journal of biological chemistry 2004;279(19):20118-26.
2004: Judit Jánossy; Paolo Ubezio; Agota Apáti; Mária Magócsi; Peter Tompa; Peter Friedrich
Calpain as a multi-site regulator of cell cycle.
Biochemical pharmacology 2004;67(8):1513-21.
2004: Peter Friedrich; Henrietta Papp; Katalin Halasy; Attila Farkas; Beatrix Farkas; Peter Tompa; Péter Kása
Differential distribution of calpain small subunit 1 and 2 in rat brain.
The European journal of neuroscience 2004;19(7):1819-25.
2004: Attila Farkas; Peter Tompa; Eva Schád; Rita Sinka; Gáspár Jékely; Peter Friedrich
Autolytic activation and localization in Schneider cells (S2) of calpain B from Drosophila.
The Biochemical journal 2004;378(Pt 2):299-305.
2003: Zoltán Mucsi; Ferenc Hudecz; Miklós Hollósi; Peter Tompa; Peter Friedrich
Binding-induced folding transitions in calpastatin subdomains A and C.
Protein science : a publication of the Protein Society 2003;12(10):2327-36.
2003: Attila Farkas; Peter Tompa; Peter Friedrich
Revisiting ubiquity and tissue specificity of human calpains.
Biological chemistry 2003;384(6):945-9.
2003: Cesare Spadoni; Attila Farkas; Rita Sinka; Peter Tompa; Peter Friedrich
Molecular cloning and RNA expression of a novel Drosophila calpain, Calpain C.
Biochemical and biophysical research communications 2003;303(1):343-9.
2002: Anita Alexa; G Schmidt; Peter Tompa; S Ogueta; J Vázquez; P Kulcsár; János Kovács; Viktor Dombrádi; Peter Friedrich
The phosphorylation state of threonine-220, a uniquely phosphatase-sensitive protein kinase A site in microtubule-associated protein MAP2c, regulates microtubule binding and stability.
Biochemistry 2002;41(41):12427-35.
2002: Peter Tompa; Gábor E Tusnády; Peter Friedrich; Istvan Simon
The role of dimerization in prion replication.
Biophysical journal 2002;82(4):1711-8.
2002: Peter Tompa; Zoltán Mucsi; György Orosz; Peter Friedrich
Calpastatin subdomains A and C are activators of calpain.
The Journal of biological chemistry 2002;277(11):9022-6.
2002: Eva Schád; Attila Farkas; Gáspár Jékely; Peter Tompa; Peter Friedrich
A novel human small subunit of calpains.
The Biochemical journal 2002;362(Pt 2):383-8.
2001: Peter Tompa; R Töth-Boconádi; Peter Friedrich
Frequency decoding of fast calcium oscillations by calpain.
Cell calcium 2001;29(3):161-70.
2001: Peter Tompa; Y Emori; Hiroyuki Sorimachi; K Suzuki; Peter Friedrich
Domain III of calpain is a ca2+-regulated phospholipid-binding domain.
Biochemical and biophysical research communications 2001;280(5):1333-9.
2000: Robert Wronski; Peter Tompa; Birgit Hutter-Paier; Karl Crailsheim; Peter Friedrich; Manfred Windisch
Inhibitory effect of a brain derived peptide preparation on the Ca++-dependent protease, calpain.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(2):145-57.
2000: Peter Tompa; Eva Schád; Peter Friedrich
A sensitive and continuous fluorometric activity assay using a natural substrate. Microtubule-associated protein 2.
Methods in molecular biology (Clifton, N.J.) 2000;144():137-41.
2000: Peter Tompa; Peter Friedrich
Kinetic analysis of human mu-calpain autolysis.
Methods in molecular biology (Clifton, N.J.) 2000;144():129-36.
2000: Gáspár Jékely; Marianna Pintér; Peter Friedrich
Drosophila calpains. Purification of a calpain-like enzyme from fruit flies, and expression in Escherichia coli.
Methods in molecular biology (Clifton, N.J.) 2000;144():67-74.
1999: Gáspár Jékely; Peter Friedrich
Characterization of two recombinant Drosophila calpains. CALPA and a novel homolog, CALPB.
The Journal of biological chemistry 1999;274(34):23893-900.
1999: Gáspár Jékely; Peter Friedrich
The evolution of the calpain family as reflected in paralogous chromosome regions.
Journal of molecular evolution 1999;49(2):272-81.
1998: Peter Tompa; Peter Friedrich
Prion proteins as memory molecules: an hypothesis.
Neuroscience 1998;86(4):1037-43.
1998: Peter Tompa; Peter Friedrich
Synaptic metaplasticity and the local charge effect in postsynaptic densities.
Trends in neurosciences 1998;21(3):97-102.
1996: Peter Tompa; A Baki; E Schád; Peter Friedrich
The calpain cascade. Mu-calpain activates m-calpain.
The Journal of biological chemistry 1996;271(52):33161-4.
1996: C Sánchez; Peter Tompa; K Szücs; Peter Friedrich; Jesús Avila
Phosphorylation and dephosphorylation in the proline-rich C-terminal domain of microtubule-associated protein 2.
European journal of biochemistry / FEBS 1996;241(3):765-71.
1996: A Baki; Peter Tompa; A Alexa; O Molnár; Peter Friedrich
Autolysis parallels activation of mu-calpain.
The Biochemical journal 1996;318 ( Pt 3)():897-901.
1996: A Alexa; Peter Tompa; A Baki; G Vereb; Peter Friedrich
Mutual protection of microtubule-associated protein 2 (MAP2) and cyclic AMP-dependent protein kinase II against mu-calpain.
Journal of neuroscience research 1996;44(5):438-45.
1995: Peter Tompa; E Schád; A Baki; A Alexa; J Batke; Peter Friedrich
An ultrasensitive, continuous fluorometric assay for calpain activity.
Analytical biochemistry 1995;228(2):287-93.
1995: Ulrich Theopold; M Pintér; S Daffre; Y Tryselius; Peter Friedrich; D R Nässel; Dan Hultmark
CalpA, a Drosophila calpain homolog specifically expressed in a small set of nerve, midgut, and blood cells.
Molecular and cellular biology 1995;15(2):824-34.
1994: M Pintér; A Aszódi; Peter Friedrich; I Ginzburg
Calpeptin, a calpain inhibitor, promotes neurite elongation in differentiating PC12 cells.
Neuroscience letters 1994;170(1):91-3.
1994: K Szücs; M D Ledesma; Viktor Dombrádi; Pál Gergely; Jesús Avila; Peter Friedrich
Dephosphorylation of tau protein from Alzheimer's disease patients.
Neuroscience letters 1994;165(1-2):175-8.
1993: L Ulloa; Viktor Dombrádi; JAVIER DIAZ-NIDO; K Szücs; Pál Gergely; Peter Friedrich; Jesús Avila
Dephosphorylation of distinct sites on microtubule-associated protein MAP1B by protein phosphatases 1, 2A and 2B.
FEBS letters 1993;330(1):85-9.
1993: Z Asztalos; J von Wegerer; G Wustmann; Viktor Dombrádi; J Gausz; H C Spatz; Peter Friedrich
Protein phosphatase 1-deficient mutant Drosophila is affected in habituation and associative learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(3):924-30.
1992: G Adám; A Udvardy; Peter Friedrich
Mouse microtubule-associated protein 2 expression in transgenic Drosophila.
Neuroscience 1992;51(1):221-30.
1992: M Pintér; A Stierandova; Peter Friedrich
Purification and characterization of a Ca(2+)-activated thiol protease from Drosophila melanogaster.
Biochemistry 1992;31(35):8201-6.
1991: Peter Friedrich; A Aszódi
MAP2: a sensitive cross-linker and adjustable spacer in dendritic architecture.
FEBS letters 1991;295(1-3):5-9.
1991: Z Asztalos; M Lossos; Peter Friedrich
On the pharmacological phenocopying of memory mutations in Drosophila: alkylxanthines accelerate memory decay.
Behavior genetics 1991;21(5):495-511.
1991: A Aszódi; U Müller; Peter Friedrich; H C Spatz
Signal convergence on protein kinase A as a molecular correlate of learning.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(13):5832-6.
1991: Peter Friedrich; Laszlo Fesus; E Tarcsa; G Czéh
Protein cross-linking by transglutaminase induced in long-term potentiation in the Ca1 region of hippocampal slices.
Neuroscience 1991;43(2-3):331-4.
1990: Peter Friedrich
Protein structure: the primary substrate for memory.
Neuroscience 1990;35(1):1-7.
1989: P Dévay; M Pintér; I Kiss; A Faragó; Peter Friedrich
Protein kinase C in larval brain of wild-type and dunce memory-mutant Drosophila.
Journal of neurogenetics 1989;5(2):119-26.
1989: Peter Friedrich; A Aszódi
Cyclic AMP turnover and signal amplification.
The Biochemical journal 1989;257(2):621-3.
1988: G Adám; Peter Friedrich
Microtubule-associated cyclic AMP-dependent protein kinase in Drosophila melanogaster.
Journal of neurochemistry 1988;51(4):1014-22.
1988: M Pintér; Peter Friedrich
The calcium-dependent proteolytic system calpain-calpastatin in Drosophila melanogaster.
The Biochemical journal 1988;253(2):467-73.
1987: P Dévay; Peter Friedrich
Cyclic AMP-induced phosphorylation of 27.5-kDa protein(s) in larval brains of normal and memory-mutant Drosophila melanogaster.
Journal of neurogenetics 1987;4(6):275-84.
1987: A Aszódi; Peter Friedrich
Molecular kinetic modelling of associative learning.
Neuroscience 1987;22(1):37-48.
1987: Viktor Dombrádi; Peter Friedrich; G Bot
Effect of ligands on Drosophila phosphorylase a as monitored by its enzymic inactivation.
The International journal of biochemistry 1987;19(7):657-9.
1986: P Dévay; M Pintér; Ahmet Suha Yalcin; Peter Friedrich
Altered autophosphorylation of adenosine 3',5'-phosphate-dependent protein kinase in the dunce memory mutant of Drosophila melanogaster.
Neuroscience 1986;18(1):193-203.
1986: Peter Friedrich; P Dévay; Viktor Dombrádi; Z Kiss; I Láng; M Pintér; M Solti
Drosophila mutants with memory deficits.
Progress in brain research 1986;69():309-21.
1986: Viktor Dombrádi; J Matkó; Z Kiss; L Kiss; Peter Friedrich; G Bot
Structural and functional properties of Drosophila melanogaster phosphorylase: comparison with the rabbit skeletal muscle enzyme.
Comparative biochemistry and physiology. B, Comparative biochemistry 1986;84(4):537-43.
1984: P Dévay; M Solti; I Kiss; Peter Friedrich
Differences in protein phosphorylation in vivo and in vitro between wild type and dunce mutant strains of Drosophila melanogaster.
The International journal of biochemistry 1984;16(12):1401-8.
1982: Viktor Dombrádi; B Tóth; G Bot; J Hajdu; Peter Friedrich
Interaction of ligands in phosphorylase A as monitored by crosslinking and enzymatic modifications: synergism of glucose and caffeine manifested in the exposure of N-terminal segment.
The International journal of biochemistry 1982;14(4):277-84.
1981: M Solti; F Bartha; N Halász; G Tóth; F Sirokmán; Peter Friedrich
Localization of glyceraldehyde-3-phosphate dehydrogenase in intact human erythrocytes. Evaluation of membrane adherence is autoradiographs at low grain density.
The Journal of biological chemistry 1981;256(17):9260-5.
1980: Viktor Dombrádi; J Hajdu; G Bot; Peter Friedrich
Structural changes in glycogen phosphorylase as revealed by cross-linking with bifunctional diimidates: phospho-dephospho hybrid and phosphorylase a.
Biochemistry 1980;19(11):2295-9.