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Robert Friesel

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TOP 3
Xuehui Yang; Yan Gong; Lindsey Gower; Qing He; Hongfang Li; Lucy Liaw; Yuefeng Tang; Robert Friesel
Spry1 and Spry4 Differentially Regulate Human Aortic Smooth Muscle Cell Phenotype via Akt/FoxO/Myocardin Signaling.
Liangru W Contois; Alexandra Cretu; Robert Friesel; Leonard Liebes; Desiree P Nugent; Clifford Rosen; Eric Tweedie; Calvin Vary; Abebe Akalu; Jennifer M Caron; Peter C Brooks
Insulin-like growth factor binding protein-4 differentially inhibits growth factor-induced angiogenesis.
Aaron Clifford Brown; Mark de Caestecker; Robert Friesel; Derek Adams; Xuehui Yang; Leif Oxburgh
FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development.

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All Publications

2013: Xuehui Yang; Yan Gong; Lindsey Gower; Qing He; Hongfang Li; Lucy Liaw; Yuefeng Tang; Robert Friesel
Spry1 and Spry4 Differentially Regulate Human Aortic Smooth Muscle Cell Phenotype via Akt/FoxO/Myocardin Signaling.
PloS one 2013;8(3):e58746.
2012: Liangru W Contois; Alexandra Cretu; Robert Friesel; Leonard Liebes; Desiree P Nugent; Clifford Rosen; Eric Tweedie; Calvin Vary; Abebe Akalu; Jennifer M Caron; Peter C Brooks
Insulin-like growth factor binding protein-4 differentially inhibits growth factor-induced angiogenesis.
The Journal of biological chemistry 2012;287(3):1779-89.
2011: Aaron Clifford Brown; Mark de Caestecker; Robert Friesel; Derek Adams; Xuehui Yang; Leif Oxburgh
FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development.
Development (Cambridge, England) 2011;138(23):5099-112.
2011: Doreen Kacer; Erin Kany; Alek Kirov; Lucy Liaw; Christian McIntire; Jennifer Roth; Deena Small; Francesca Tarantini; Joseph Verdi; Claudio Basilico; Robert Friesel; Igor Prudovsky
Regulation of non-classical FGF1 release and FGF-dependent cell transformation by CBF1-mediated notch signaling.
Journal of cellular physiology 2011;226(11):3064-75.
2011: Hector L Franco; Robert Friesel; Yongchao Ge; Ruth G Leon; Jose J Casasnovas; Robert J Desnick; Carmen L Cadilla
Nonsense mutations of the bHLH transcription factor TWIST2 found in Setleis Syndrome patients cause dysregulation of periostin.
The international journal of biochemistry & cell biology 2011;43(10):1523-31.
2011: Yuefeng Tang; Calvin P H Vary; Xuehui Yang; Robert Friesel; Lucy Liaw
Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells.
Journal of vascular research 2011;48(6):485-94.
2011: Xuehui Yang; Yan Gong; Robert Friesel
Spry1 is expressed in hemangioblasts and negatively regulates primitive hematopoiesis and endothelial cell function.
PloS one 2011;6(4):e18374.
2010: Yuefeng Tang; Anne Harrington; Xuehui Yang; Robert Friesel; Lucy Liaw
The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells.
Genesis (New York, N.Y. : 2000) 2010;48(9):563-7.
2010: Sangjin Lee; Tri M Bui Nguyen; Dmitry Kovalenko; Neeta Adhikari; Suzanne Grindle; Sean P Polster; Robert Friesel; Sundaram Ramakrishnan; Jennifer L Hall
Sprouty1 inhibits angiogenesis in association with up-regulation of p21 and p27.
Molecular and cellular biochemistry 2010;338(1-2):255-61.
2010: Aldona Karaczyn; Mahmud Bani-Yaghoub; Roger Tremblay; Chris Kubu; Rebecca Cowling; Tamara L Adams; Igor Prudovsky; Douglas Spicer; Robert Friesel; Calvin Vary; Joseph M Verdi
Two novel human NUMB isoforms provide a potential link between development and cancer.
Neural development 2010;5():31.
2010: Xuehui Yang; Sean Kilgallen; Viktoria Andreeva; Douglas B Spicer; Ilka Pinz; Robert Friesel
Conditional expression of Spry1 in neural crest causes craniofacial and cardiac defects.
BMC developmental biology 2010;10():48.
2009: Pei-Yu Chen; Michael Simons; Robert Friesel
FRS2 via fibroblast growth factor receptor 1 is required for platelet-derived growth factor receptor beta-mediated regulation of vascular smooth muscle marker gene expression.
The Journal of biological chemistry 2009;284(23):15980-92.
2009: Pei-Yu Chen; Robert Friesel
FGFR1 forms an FRS2-dependent complex with mTOR to regulate smooth muscle marker gene expression.
Biochemical and biophysical research communications 2009;382(2):424-9.
2008: Maria Duarte; Vihren Kolev; Doreen Kacer; Carla Mouta-Bellum; Raffaella Soldi; Irene Graziani; Aleksandr Kirov; Robert Friesel; Lucy Liaw; Deena Small; Joseph Verdi; Thomas Maciag; Igor Prudovsky
Novel cross-talk between three cardiovascular regulators: thrombin cleavage fragment of Jagged1 induces fibroblast growth factor 1 expression and release.
Molecular biology of the cell 2008;19(11):4863-74.
2008: Xuehui Yang; Lauren K Harkins; Olga Zubanova; Anne Harrington; Dmitry Kovalenko; Robert J Nadeau; Pei-Yu Chen; Jessica L Toher; Volkhard Lindner; Lucy Liaw; Robert Friesel
Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia.
Developmental biology 2008;321(1):64-76.
2007: George N Nikopoulos; Maria Duarte; Chris J Kubu; Stephen Bellum; Robert Friesel; Thomas Maciag; Igor Prudovsky; Joseph M Verdi
Soluble Jagged1 attenuates lateral inhibition, allowing for the clonal expansion of neural crest stem cells.
Stem cells (Dayton, Ohio) 2007;25(12):3133-42.
2007: Christine F O'Neill; Sumithra Urs; Christina Cinelli; Alexis Lincoln; Robert J Nadeau; Ruth León; Jessica Toher; Carla Mouta-Bellum; Robert Friesel; Lucy Liaw
Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.
The American journal of pathology 2007;171(3):1023-36.
2007: Robert J Nadeau; Jessica L Toher; Xuehui Yang; Dmitry Kovalenko; Robert Friesel
Regulation of Sprouty2 stability by mammalian Seven-in-Absentia homolog 2.
Journal of cellular biochemistry 2007;100(1):151-60.
2006: Maria Duarte; Vihren Kolev; Raffaella Soldi; Alexander Kirov; Irene Graziani; Silvia Marta Oliveira; Doreen Kacer; Robert Friesel; Thomas Maciag; Igor Prudovsky
Thrombin induces rapid PAR1-mediated non-classical FGF1 release.
Biochemical and biophysical research communications 2006;350(3):604-9.
2006: Dmitry Kovalenko; Xuehui Yang; Pei-Yu Chen; Robert J Nadeau; Olga Zubanova; Kathleen Pigeon; Robert Friesel
A role for extracellular and transmembrane domains of Sef in Sef-mediated inhibition of FGF signaling.
Cellular signalling 2006;18(11):1958-66.
2006: Xuehui Yang; J B Webster; Dmitry Kovalenko; Robert J Nadeau; Olga Zubanova; Pei-Yu Chen; Robert Friesel
Sprouty genes are expressed in osteoblasts and inhibit fibroblast growth factor-mediated osteoblast responses.
Calcified tissue international 2006;78(4):233-40.
2005: Peter Pyagay; Mélanie Heroult; Qiaozeng Wang; Wolfgang Lehnert; John Belden; Lucy Liaw; Robert Friesel; Volkhard Lindner
Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration.
Circulation research 2005;96(2):261-8.
2005: Volkhard Lindner; Qiaozeng Wang; Barbara A Conley; Robert Friesel; Calvin P H Vary
Vascular injury induces expression of periostin: implications for vascular cell differentiation and migration.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(1):77-83.
2004: Xuehui Yang; Dmitry Kovalenko; Robert J Nadeau; Lauren K Harkins; Jane Mitchell; Olga Zubanova; Pei-Yu Chen; Robert Friesel
Sef interacts with TAK1 and mediates JNK activation and apoptosis.
The Journal of biological chemistry 2004;279(37):38099-102.
2003: Dmitry Kovalenko; Xuehui Yang; Robert J Nadeau; Lauren K Harkins; Robert Friesel
Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.
The Journal of biological chemistry 2003;278(16):14087-91.
2002: Kathleen Mood; Robert Friesel; Ira O Daar
SNT1/FRS2 mediates germinal vesicle breakdown induced by an activated FGF receptor1 in Xenopus oocytes.
The Journal of biological chemistry 2002;277(36):33196-204.
2002: Michael Tsang; Robert Friesel; Tetsuhiro Kudoh; Igor B Dawid
Identification of Sef, a novel modulator of FGF signalling.
Nature cell biology 2002;4(2):165-9.
2000: LD Chong; Eui Kyun Park; E Latimer; Robert Friesel; Ira O Daar
Fibroblast growth factor receptor-mediated rescue of x-ephrin B1-induced cell dissociation in Xenopus embryos.
Molecular and cellular biology 2000;20(2):724-34.
1999: Robert Friesel; Thomas Maciag
Fibroblast growth factor prototype release and fibroblast growth factor receptor signaling.
Thrombosis and haemostasis 1999;82(2):748-54.