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Philippe Frit

Research Profile

Chemicals & Drugs

Physiology

DNA Repair

Disorders

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Cricetinae

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Publications

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Jessica Cottarel; Philippe Frit; Penny A Jeggo; Michael R Lieber; Mauro Modesti; Aurélie Négrel; Bernard Salles; Stéphanie Bernard; Oriane Bombarde; Patrick Calsou
A noncatalytic function of the ligation complex during nonhomologous end joining.
Fanny Bouquet; Marielle Ousset; Denis Biard; Frédérique Fallone; Stéphanie Dauvillier; Philippe Frit; Bernard Salles; Catherine Muller
A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia.
Oriane Bombarde; Céline Boby; Dennis Gomez; Philippe Frit; Marie-Josèphe Giraud-Panis; Eric Gilson; bernard salles; Patrick Calsou
TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends.

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All Publications

2013: Jessica Cottarel; Philippe Frit; Penny A Jeggo; Michael R Lieber; Mauro Modesti; Aurélie Négrel; Bernard Salles; Stéphanie Bernard; Oriane Bombarde; Patrick Calsou
A noncatalytic function of the ligation complex during nonhomologous end joining.
The Journal of cell biology 2013;200(2):173-86.
2011: Fanny Bouquet; Marielle Ousset; Denis Biard; Frédérique Fallone; Stéphanie Dauvillier; Philippe Frit; Bernard Salles; Catherine Muller
A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia.
Journal of cell science 2011;124(Pt 11):1943-51.
2010: Oriane Bombarde; Céline Boby; Dennis Gomez; Philippe Frit; Marie-Josèphe Giraud-Panis; Eric Gilson; bernard salles; Patrick Calsou
TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends.
The EMBO journal 2010;29(9):1573-84.
2009: Sébastien Britton; Carine Froment; Philippe Frit; Bernard Monsarrat; bernard salles; Patrick Calsou
Cell nonhomologous end joining capacity controls SAF-A phosphorylation by DNA-PK in response to DNA double-strand breaks inducers.
Cell cycle (Georgetown, Tex.) 2009;8(22):3717-22.
2009: Sébastien Britton; Philippe Frit; Denis Biard; bernard salles; Patrick Calsou
ARTEMIS nuclease facilitates apoptotic chromatin cleavage.
Cancer research 2009;69(20):8120-6.
2009: Peï-Yu Wu; Philippe Frit; SriLakshmi Meesala; Stéphanie Dauvillier; Mauro Modesti; Sara N Andres; Ying Huang; JoAnn Sekiguchi; Patrick Calsou; bernard salles; Murray S Junop
Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4.
Molecular and cellular biology 2009;29(11):3163-72.
2007: Peï-Yu Wu; Philippe Frit; Laurent Malivert; Patrick Revy; Denis S F Biard; bernard salles; Patrick Calsou
Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell.
The Journal of biological chemistry 2007;282(44):31937-43.
2006: Jérôme Drouet; Philippe Frit; Christine Delteil; Jean-Pierre De Villartay; bernard salles; Patrick Calsou
Interplay between Ku, Artemis, and the DNA-dependent protein kinase catalytic subunit at DNA ends.
The Journal of biological chemistry 2006;281(38):27784-93.
2006: bernard salles; Patrick Calsou; Philippe Frit; Catherine Muller
The DNA repair complex DNA-PK, a pharmacological target in cancer chemotherapy and radiotherapy.
Pathologie-biologie 2006;54(4):185-93.
2004: sylvie monferran; Catherine Muller; Lionel Mourey; Philippe Frit; bernard salles
The Membrane-associated form of the DNA repair protein Ku is involved in cell adhesion to fibronectin.
Journal of molecular biology 2004;337(3):503-11.
2003: Ulrike Sattler; Philippe Frit; bernard salles; Patrick Calsou
Long-patch DNA repair synthesis during base excision repair in mammalian cells.
EMBO reports 2003;4(4):363-7.
2003: Patrick Calsou; Christine Delteil; Philippe Frit; Jérôme Drouet; bernard salles
Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.
Journal of molecular biology 2003;326(1):93-103.
2002: Philippe Frit; Kyungrim Kwon; Frédéric Coin; Jerome Auriol; Sandy Dubaele; bernard salles; Jean-Marc Egly
Transcriptional activators stimulate DNA repair.
Molecular cell 2002;10(6):1391-401.
2000: Philippe Frit; R Y Li; D Arzel; bernard salles; Patrick Calsou
Ku entry into DNA inhibits inward DNA transactions in vitro.
The Journal of biological chemistry 2000;275(46):35684-91.
2000: Wim Vermeulen; E Bergmann; Jerome Auriol; Suzanne Rademakers; Philippe Frit; Esther Appeldoorn; Jan H J Hoeijmakers; Jean-Marc Egly
Sublimiting concentration of TFIIH transcription/DNA repair factor causes TTD-A trichothiodystrophy disorder.
Nature genetics 2000;26(3):307-13.
1999: Philippe Frit; Yvan Canitrot; Catherine Muller; Nicolas Foray; Patrick Calsou; Elizabeth Marangoni; Jean Bourhis; bernard salles
Cross-resistance to ionizing radiation in a murine leukemic cell line resistant to cis-dichlorodiammineplatinum(II): role of Ku autoantigen.
Molecular pharmacology 1999;56(1):141-6.
1999: Patrick Calsou; Philippe Frit; Odile Humbert; Catherine Muller; D J Chen; bernard salles
The DNA-dependent protein kinase catalytic activity regulates DNA end processing by means of Ku entry into DNA.
The Journal of biological chemistry 1999;274(12):7848-56.
1999: Catherine Muller; Patrick Calsou; Philippe Frit; bernard salles
Regulation of the DNA-dependent protein kinase (DNA-PK) activity in eukaryotic cells.
Biochimie 1999;81(1-2):117-25.
1999: Philippe Frit; E Bergmann; Jean-Marc Egly
Transcription factor IIH: a key player in the cellular response to DNA damage.
Biochimie 1999;81(1-2):27-38.
1998: Philippe Frit; Patrick Calsou; D J Chen; bernard salles
Ku70/Ku80 protein complex inhibits the binding of nucleotide excision repair proteins on linear DNA in vitro.
Journal of molecular biology 1998;284(4):963-73.
1998: Frédéric Coin; Philippe Frit; B Viollet; bernard salles; Jean-Marc Egly
TATA binding protein discriminates between different lesions on DNA, resulting in a transcription decrease.
Molecular and cellular biology 1998;18(7):3907-14.
1998: Catherine Muller; Patrick Calsou; Philippe Frit; Corinne Cayrol; T Carter; bernard salles
UV sensitivity and impaired nucleotide excision repair in DNA-dependent protein kinase mutant cells.
Nucleic acids research 1998;26(6):1382-9.
1997: Yvan Canitrot; Philippe Frit; bernard salles
Deficient apoptotic process in cisplatin-resistant L1210 cells cannot account for the cellular response to various drug treatments.
Biochemical and biophysical research communications 1997;234(3):573-7.
1996: Patrick Calsou; Philippe Frit; C Bozzato; bernard salles
Negative interference of metal (II) ions with nucleotide excision repair in human cell-free extracts.
Carcinogenesis 1996;17(12):2779-82.
1996: Patrick Calsou; Philippe Frit; bernard salles
Double strand breaks in DNA inhibit nucleotide excision repair in vitro.
The Journal of biological chemistry 1996;271(44):27601-7.
1996: Patrick Calsou; Catherine Muller; Philippe Frit; bernard salles
Ku protein complex is involved in nucleotide excision repair of DNA.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1996;319(3):179-82.
1995: bernard salles; Philippe Frit; C Provot; J P Jaeg; Patrick Calsou
In vitro eukaryotic DNA excision repair assays: an overview.
Biochimie 1995;77(10):796-802.
1992: Patrick Calsou; Philippe Frit; bernard salles
Repair synthesis by human cell extracts in cisplatin-damaged DNA is preferentially determined by minor adducts.
Nucleic acids research 1992;20(23):6363-8.