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Andreas Fritsche

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Jürgen Machann; Christoph Schabel; Claus D Claussen; Andreas Fritsche; Hans-Ulrich Häring; Erwin Schleicher; Norbert Stefan; Christian Würslin; Fritz Schick
Fraction of unsaturated fatty acids in visceral adipose tissue (VAT) is lower in subjects with high total VAT volume - a combined 1 H MRS and volumetric MRI study in male subjects.
Harald Staiger; Norbert Stefan; Cora Weigert; Lucia Berti; Anja Böhm; Andreas Fritsche; Hans-Ulrich Häring; Anna Krook; Jürgen Machann; Fausto Machicao; Mika Scheler; Fritz Schick; Martin Hrabě de Angelis
Common Genetic Variation in the Human FNDC5 Locus, Encoding the Novel Muscle-Derived 'Browning' Factor Irisin, Determines Insulin Sensitivity.
Stephanie Kullmann; Ralf Veit; Sabine Frank; Andreas Fritsche; Hans-Ulrich Häring; Martin Heni; Caroline Ketterer; Hubert Preissl
Intranasal insulin modulates intrinsic reward and prefrontal circuitry of the human brain in lean women.

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2013: Jürgen Machann; Christoph Schabel; Claus D Claussen; Andreas Fritsche; Hans-Ulrich Häring; Erwin Schleicher; Norbert Stefan; Christian Würslin; Fritz Schick
Fraction of unsaturated fatty acids in visceral adipose tissue (VAT) is lower in subjects with high total VAT volume - a combined 1 H MRS and volumetric MRI study in male subjects.
NMR in biomedicine 2013;26(2):232-6.
2013: Harald Staiger; Norbert Stefan; Cora Weigert; Lucia Berti; Anja Böhm; Andreas Fritsche; Hans-Ulrich Häring; Anna Krook; Jürgen Machann; Fausto Machicao; Mika Scheler; Fritz Schick; Martin Hrabě de Angelis
Common Genetic Variation in the Human FNDC5 Locus, Encoding the Novel Muscle-Derived 'Browning' Factor Irisin, Determines Insulin Sensitivity.
PloS one 2013;8(4):e61903.
2013: Stephanie Kullmann; Ralf Veit; Sabine Frank; Andreas Fritsche; Hans-Ulrich Häring; Martin Heni; Caroline Ketterer; Hubert Preissl
Intranasal insulin modulates intrinsic reward and prefrontal circuitry of the human brain in lean women.
Neuroendocrinology 2013;97(2):176-82.
2012: Günther Silbernagel; Norbert Stefan; Fritz Schick; Erwin Schleicher; Alexander Cegan; Andreas Fritsche; Hans-Ulrich Häring; Marketa Kovarova; Rainer Lehmann; Jürgen Machann; Andreas Peter
High hepatic SCD1 activity is associated with low liver fat content in healthy subjects under a lipogenic diet.
The Journal of clinical endocrinology and metabolism 2012;97(12):E2288-92.
2012: S Herzberg-Schäfer; Norbert Stefan; Hans-Ulrich Häring; M Heni; Andreas Fritsche
Impairment of GLP1-induced insulin secretion: role of genetic background, insulin resistance and hyperglycaemia.
Diabetes, obesity & metabolism 2012;14 Suppl 3():85-90.
2012: Robert Wagner; Ferruh Artunc; C D Claussen; Andreas Fritsche; Hans-Ulrich Häring; R Lehmann; J Lenhart; K Linder; Jürgen Machann; Kilian Rittig; Fritz Schick; E Schleicher; Peter Weyrich
Exercise-induced albuminuria is associated with perivascular renal sinus fat in individuals at increased risk of type 2 diabetes.
Diabetologia 2012;55(7):2054-8.
2012: Sabine Frank; Andreas Fritsche; Hans-Ulrich Häring; Martin Heni; Jörg Hinrichs; Caroline Ketterer; Alina Krzeminski; Stephanie Kullmann; Katarzyna Linder; Hubert Preissl; Mustafa Cavusoglu; Ralf Veit
Fat intake modulates cerebral blood flow in homeostatic and gustatory brain areas in humans.
The American journal of clinical nutrition 2012;95(6):1342-9.
2012: M Heni; C Ketterer; S Kullmann; K Linder; Hubert Preissl; Harald Staiger; K T Stingl; Ralf Veit; Robert Wagner; M Guthoff; Hans-Ulrich Häring; Andreas Fritsche
Nasal insulin changes peripheral insulin sensitivity simultaneously with altered activity in homeostatic and reward-related human brain regions.
Diabetologia 2012;55(6):1773-82.
2012: A Peter; F Schick; S Templin; S Wagner; Andreas Fritsche; H-U Häring; Konstantinos Kantartzis; A Königsrainer; Ingmar Königsrainer; J Machann; Fausto Machicao; N Stefan
Visceral obesity modulates the impact of apolipoprotein C3 gene variants on liver fat content.
International journal of obesity (2005) 2012;36(6):774-82.
2012: Stephanie Kullmann; Fritz Schick; Ralf Veit; Andreas Fritsche; Hans-Ulrich Häring; Martin Heni; Caroline Ketterer; Hubert Preissl
The obese brain: association of body mass index and insulin sensitivity with resting state network functional connectivity.
Human brain mapping 2012;33(5):1052-61.
2012: Krunoslav T Stingl; Andreas Fritsche; Hans-Ulrich Häring; Martin Heni; Caroline Ketterer; Stephanie Kullmann; Hubert Preissl
Neuronal correlates of reduced memory performance in overweight subjects.
NeuroImage 2012;60(1):362-9.
2012: Tina Sartorius; Matthias B Schulze; Harald Staiger; Norbert Stefan; Heiner Boeing; Michael P Czech; Andreas Fritsche; Harald Grallert; Adilson Guilherme; Martin Heni; Caroline Ketterer; Fausto Machicao; Hans-Ulrich Häring
Association of common genetic variants in the MAP4K4 locus with prediabetic traits in humans.
PloS one 2012;7(10):e47647.
2012: Katarzyna Linder; Fausto Machicao; Harald Staiger; Norbert Stefan; Robert Wagner; Hans-Ulrich Häring; Erifili Hatziagelaki; Martin Heni; Caroline Ketterer; Andreas Fritsche
Allele summation of diabetes risk genes predicts impaired glucose tolerance in female and obese individuals.
PloS one 2012;7(6):e38224.
2012: Tina Sartorius; Harald Staiger; Mohammed Taouis; Otto Tschritter; Flavien Berthou; Andreas Fritsche; Arieh Gertler; Hans-Ulrich Häring; Martin Heni; Sabine Hopp; Paul-Simon Lievertz; Hubert Preissl; Anita M Hennige
Leptin affects insulin action in astrocytes and impairs insulin-mediated physical activity.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2012;30(1):238-46.
2012: Anja Böhm; Andreas Fritsche; Hans-Ulrich Häring; Martin Heni; Caroline Ketterer; Jürgen Machann; Fausto Machicao; Anna-Maria Ordelheide; Fritz Schick; Norbert Stefan; Harald Staiger
Common genetic variation in the SERPINF1 locus determines overall adiposity, obesity-related insulin resistance, and circulating leptin levels.
PloS one 2012;7(3):e34035.
2012: Otto Tschritter; Andreas Fritsche; M Heni; Anita M Hennige; C Ketterer; Jürgen Machann; Hubert Preissl; T Sartorius; E Schleicher; Norbert Stefan; K T Stingl; Hans-Ulrich Häring
High cerebral insulin sensitivity is associated with loss of body fat during lifestyle intervention.
Diabetologia 2012;55(1):175-82.
2011: Burkhard Ludescher; Marc Rommel; Fritz Schick; Tobias Willmer; Andreas Fritsche; Juergen Machann
Subcutaneous adipose tissue thickness in adults - correlation with BMI and recommendations for pen needle lengths for subcutaneous self-injection.
Clinical endocrinology 2011;75(6):786-90.
2011: Anna-Maria Ordelheide; Norbert Stefan; Claus Thamer; Andreas Fritsche; Hans-Ulrich Häring; Martin Heni; Fausto Machicao; Harald Staiger
In vitro responsiveness of human muscle cell peroxisome proliferator-activated receptor δ reflects donors' insulin sensitivity in vivo.
European journal of clinical investigation 2011;41(12):1323-9.
2011: Caroline Ketterer; Fausto Machicao; Karsten Müssig; Elko Randrianarisoa; Katarzyna Dudziak; Andreas Fritsche; Hans-Ulrich Häring; Martin Heni; Jens J Holst; Norbert Stefan; Robert Wagner; Harald Staiger
Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes.
Metabolism: clinical and experimental 2011;60(9):1325-33.
2011: Silke A Schäfer; Fausto Machicao; Andreas Fritsche; Hans-Ulrich Häring; Konstantinos Kantartzis
New type 2 diabetes risk genes provide new insights in insulin secretion mechanisms.
Diabetes research and clinical practice 2011;93 Suppl 1():S9-24.
2011: Caroline Ketterer; Hubert Preissl; Otto Tschritter; Hans-Ulrich Häring; Martin Heni; Andreas Fritsche
Insulin sensitivity of the human brain.
Diabetes research and clinical practice 2011;93 Suppl 1():S47-51.
2011: C Ketterer; Claus Thamer; H-U Häring; M Heni; S A Herzberg-Schäfer; Andreas Fritsche
Acute, short-term hyperinsulinemia increases olfactory threshold in healthy subjects.
International journal of obesity (2005) 2011;35(8):1135-8.
2011: Guenther Silbernagel; Norbert Stefan; Susanne Unmuth; Hans U Häring; Juergen Machann; Fritz Schick; Andreas Fritsche
Effects of 4-week very-high-fructose/glucose diets on insulin sensitivity, visceral fat and intrahepatic lipids: an exploratory trial.
The British journal of nutrition 2011;106(1):79-86.
2011: Charisis Totsikas; Julian Röhm; Konstantinos Kantartzis; Claus Thamer; Kilian Rittig; Jürgen Machann; Fritz Schick; Jochen Hansel; Andreas Niess; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan
Cardiorespiratory fitness determines the reduction in blood pressure and insulin resistance during lifestyle intervention.
Journal of hypertension 2011;29(6):1220-7.
2011: Kilian Rittig; Harald Staiger; Norbert Stefan; Claus Thamer; Bernd M Balletshofer; Andreas Fritsche; Hans-Ulrich Häring; U Hildebrandt; A Peter; Dorothea Siegel-Axel
Apelin serum levels are not associated with early atherosclerosis or fat distribution in young subjects with increased risk for type 2 diabetes.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2011;119(6):358-61.
2011: M Guthoff; HU Haering; Inga Liepelt; Fausto Machicao; C Schulte; Otto Tschritter; Daniela Berg; H Breer; Andreas Fritsche
A polymorphism in the gene encoding AdipoR1 affects olfactory recognition.
International journal of obesity (2005) 2011;35(6):873-6.
2011: Martin Heni; Karsten Müssig; Fausto Machicao; Jürgen Machann; Fritz Schick; Claus D Claussen; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring; Harald Staiger
Variants in the CD36 gene locus determine whole-body adiposity, but have no independent effect on insulin sensitivity.
Obesity (Silver Spring, Md.) 2011;19(5):1004-9.
2011: Konstantinos Kantartzis; Jürgen Machann; Fritz Schick; Kilian Rittig; Fausto Machicao; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan
Effects of a lifestyle intervention in metabolically benign and malign obesity.
Diabetologia 2011;54(4):864-8.
2011: Karsten Müssig; Harald Staiger; Konstantinos Kantartzis; Andreas Fritsche; Lothar Kanz; Hans-Ulrich Häring
Type 2 diabetes mellitus and risk of malignancy: is there a strategy to identify a subphenotype of patients with increased susceptibility to endogenous and exogenous hyperinsulinism?
Diabetic medicine : a journal of the British Diabetic Association 2011;28(3):276-86.
2011: Jürgen Machann; Manuela Etzel; Claus Thamer; Hans-Ulrich Haring; Claus D Claussen; Andreas Fritsche; Fritz Schick
Morning to evening changes of intramyocellular lipid content in dependence on nutrition and physical activity during one single day: a volume selective 1H-MRS study.
Magma (New York, N.Y.) 2011;24(1):29-33.
2011: Robert Wagner; Katarzyna Dudziak; Hans-Ulrich Häring; Silke A Herzberg-Schäfer; Fausto Machicao; Harald Staiger; Norbert Stefan; Andreas Fritsche
Glucose-raising genetic variants in MADD and ADCY5 impair conversion of proinsulin to insulin.
PloS one 2011;6(8):e23639.
2011: Otto Tschritter; Andreas Fritsche; Axel Haupt; Anita M Hennige; Caroline Ketterer; Fausto Machicao; Hubert Preissl; Tina Sartorius; Hans-Ulrich Häring
An Obesity Risk SNP (rs17782313) near the MC4R Gene Is Associated with Cerebrocortical Insulin Resistance in Humans.
Journal of obesity 2011;2011():283153.
2011: Martin Heni; Anita M Hennige; Norbert Krebs; Fausto Machicao; Anna-Maria Ordelheide; Andreas Peter; Dorothea Siegel-Axel; Andreas Fritsche; Hans-Ulrich Häring; Harald Staiger
Insulin promotes glycogen storage and cell proliferation in primary human astrocytes.
PloS one 2011;6(6):e21594.
2011: Caroline Ketterer; Karsten Müssig; Fausto Machicao; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring; Harald Staiger
Genetic variation within the NR1H2 gene encoding liver X receptor β associates with insulin secretion in subjects at increased risk for type 2 diabetes.
Journal of molecular medicine (Berlin, Germany) 2011;89(1):75-81.
2010: Karsten Müssig; Harald Staiger; Fausto Machicao; Hans-Ulrich Häring; Andreas Fritsche
Genetic variants affecting incretin sensitivity and incretin secretion.
Diabetologia 2010;53(11):2289-97.
2010: Jürgen Machann; Claus Thamer; Norbert Stefan; Nina F Schwenzer; Konstantinos Kantartzis; Hans-Ulrich Häring; Claus D Claussen; Andreas Fritsche; Fritz Schick
Follow-up whole-body assessment of adipose tissue compartments during a lifestyle intervention in a large cohort at increased risk for type 2 diabetes.
Radiology 2010;257(2):353-63.
2010: Kilian Rittig; A Hieronimus; Claus Thamer; Jürgen Machann; A Peter; Jan Stock; Fritz Schick; Andreas Fritsche; Norbert Stefan; Hans-Ulrich Häring; Bernd M Balletshofer
Reducing visceral adipose tissue mass is essential for improving endothelial function in type 2 diabetes prone individuals.
Atherosclerosis 2010;212(2):575-9.
2010: Claus Thamer; Jürgen Machann; Harald Staiger; Karsten Müssig; Nina Schwenzer; Burkhard Ludescher; Fausto Machicao; Claus Claussen; Andreas Fritsche; Fritz Schick; Norbert Stefan; Hans-Ulrich Häring
Interscapular fat is strongly associated with insulin resistance.
The Journal of clinical endocrinology and metabolism 2010;95(10):4736-42.
2010: Krunoslav T Stingl; Maja Rogić; Katarína Stingl; Carlos Canova; Otto Tschritter; Christoph Braun; Andreas Fritsche; Hubert Preissl
The temporal sequence of magnetic brain activity for food categorization and memorization--an exploratory study.
NeuroImage 2010;52(4):1584-91.
2010: Sabine Frank; Naima Laharnar; Stephanie Kullmann; Ralf Veit; Carlos Canova; Yiwen Li Hegner; Andreas Fritsche; Hubert Preissl
Processing of food pictures: influence of hunger, gender and calorie content.
Brain research 2010;1350():159-66.
2010: Karsten Müssig; Harald Staiger; Fausto Machicao; Hans-Ulrich Häring; Andreas Fritsche
Genetic variants in MTNR1B affecting insulin secretion.
Annals of medicine 2010;42(6):387-93.
2010: Fabian Springer; Jürgen Machann; Nina F Schwenzer; Verena Ballweg; Christian Würslin; Joachim H Schneider; Andreas Fritsche; Claus D Claussen; Fritz Schick
Quantitative assessment of intrahepatic lipids using fat-selective imaging with spectral-spatial excitation and in-/opposed-phase gradient echo imaging techniques within a study population of extremely obese patients: feasibility on a short, wide-bore MR scanner.
Investigative radiology 2010;45(8):484-90.
2010: Fabian Springer; Manuel Schwarz; Jürgen Machann; Andreas Fritsche; Claus D Claussen; Fritz Schick; JH Schneider
Quantitative assessment of visceral fat in morbidly obese patients by means of wide-bore MRI and its relation to lower esophageal sphincter pressure and signs of gastroesophageal reflux.
Obesity surgery 2010;20(6):749-56.
2010: Christoph Laske; Sabine Banschbach; Elke Stransky; Sabine Bosch; Guido Straten; Jürgen Machann; Andreas Fritsche; Arno Hipp; Andreas Niess; Gerhard W Eschweiler
Exercise-induced normalization of decreased BDNF serum concentration in elderly women with remitted major depression.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2010;13(5):595-602.
2010: Axel Haupt; Claus Thamer; Martin Heni; Fausto Machicao; Jürgen Machann; Fritz Schick; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring; Harald Staiger
Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study.
Obesity (Silver Spring, Md.) 2010;18(6):1212-7.
2010: Konstantinos Kantartzis; Jürgen Machann; Fritz Schick; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan
The impact of liver fat vs visceral fat in determining categories of prediabetes.
Diabetologia 2010;53(5):882-9.
2010: Martin Heni; Jürgen Machann; Harald Staiger; Nina F Schwenzer; Andreas Peter; Fritz Schick; Claus D Claussen; Norbert Stefan; Hans-Ulrich Häring; Andreas Fritsche
Pancreatic fat is negatively associated with insulin secretion in individuals with impaired fasting glucose and/or impaired glucose tolerance: a nuclear magnetic resonance study.
Diabetes/metabolism research and reviews 2010;26(3):200-5.
2010: Karsten Müssig; M Heni; Claus Thamer; Konstantinos Kantartzis; Fausto Machicao; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring; Harald Staiger
The ENPP1 K121Q polymorphism determines individual susceptibility to the insulin-sensitising effect of lifestyle intervention.
Diabetologia 2010;53(3):504-9.
2010: Andreas Fritsche; M Larbig; D Owens; Hans-Ulrich Häring
Comparison between a basal-bolus and a premixed insulin regimen in individuals with type 2 diabetes-results of the GINGER study.
Diabetes, obesity & metabolism 2010;12(2):115-23.
2010: Norbert Stefan; Konstantinos Kantartzis; Nora Celebi; Harald Staiger; Jürgen Machann; Fritz Schick; Alexander Cegan; Michaela Elcnerova; Erwin Schleicher; Andreas Fritsche; Hans-Ulrich Häring
Circulating palmitoleate strongly and independently predicts insulin sensitivity in humans.
Diabetes care 2010;33(2):405-7.
2010: Krunoslav T Stingl; Stephanie Kullmann; Martina Guthoff; Martin Heni; Andreas Fritsche; Hubert Preissl
Insulin modulation of magnetoencephalographic resting state dynamics in lean and obese subjects.
Frontiers in systems neuroscience 2010;4():157.
2010: Silke A Herzberg-Schäfer; Harald Staiger; Martin Heni; Caroline Ketterer; Martina Guthoff; Konstantinos Kantartzis; Fausto Machicao; Norbert Stefan; Hans-Ulrich Häring; Andreas Fritsche
Evaluation of fasting state-/oral glucose tolerance test-derived measures of insulin release for the detection of genetically impaired β-cell function.
PloS one 2010;5(12):e14194.
2010: Peter Weyrich; Harald Staiger; Alena Stančáková; Fausto Machicao; Jürgen Machann; Fritz Schick; Norbert Stefan; Johanna Kuusisto; Markku Laakso; Silke Schäfer; Andreas Fritsche; Hans-Ulrich Häring
The D299G/T399I Toll-like receptor 4 variant associates with body and liver fat: results from the TULIP and METSIM Studies.
PloS one 2010;5(11):e13980.
2010: Martin Heni; Axel Haupt; Silke A Schäfer; Caroline Ketterer; Claus Thamer; Fausto Machicao; Norbert Stefan; Harald Staiger; Hans-Ulrich Häring; Andreas Fritsche
Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion.
BMC medical genetics 2010;11():86.
2010: Karsten Müssig; Fausto Machicao; Jürgen Machann; Fritz Schick; Claus D Claussen; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring; Harald Staiger
No association between variation in the NR4A1 gene locus and metabolic traits in white subjects at increased risk for type 2 diabetes.
BMC medical genetics 2010;11():84.
2009: Karsten Müssig; Harald Staiger; Fausto Machicao; Jürgen Machann; Fritz Schick; Silke A Schäfer; Claus D Claussen; Jens J Holst; Baptist Gallwitz; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring
Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus.
Metabolism: clinical and experimental 2009;58(12):1809-11.
2009: Kilian Rittig; Claus Thamer; Axel Haupt; Jürgen Machann; Andreas Peter; Bernd M Balletshofer; Andreas Fritsche; Hans-Ulrich Haring; Norbert Stefan
High plasma fetuin-A is associated with increased carotid intima-media thickness in a middle-aged population.
Atherosclerosis 2009;207(2):341-2.
2009: Otto Tschritter; Hubert Preissl; Anita M Hennige; Tina Sartorius; Yuko Grichisch; Norbert Stefan; Martina Guthoff; Stephan Düsing; Jürgen Machann; Erwin Schleicher; Alexander Cegan; Niels Birbaumer; Andreas Fritsche; Hans-Ulrich Häring
The insulin effect on cerebrocortical theta activity is associated with serum concentrations of saturated nonesterified Fatty acids.
The Journal of clinical endocrinology and metabolism 2009;94(11):4600-7.
2009: Anita M Hennige; T Sartorius; S Z Lutz; Otto Tschritter; Hubert Preissl; S Hopp; Andreas Fritsche; Hans-Georg Rammensee; P Ruth; Hans-Ulrich Häring
Insulin-mediated cortical activity in the slow frequency range is diminished in obese mice and promotes physical inactivity.
Diabetologia 2009;52(11):2416-24.
2009: Konstantinos Kantartzis; Andreas Peter; Fausto Machicao; Jürgen Machann; Silvia Wagner; Ingmar Königsrainer; Alfred Königsrainer; Fritz Schick; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan
Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene.
Diabetes 2009;58(11):2616-23.
2009: Otto Tschritter; Silke A Schäfer; J Klett; Albrecht Pfäfflin; Hans-Ulrich Häring; Anita M Hennige; Andreas Fritsche
Insulin detemir causes increased symptom awareness during hypoglycaemia compared to human insulin.
Diabetes, obesity & metabolism 2009;11(11):1017-26.
2009: Axel Haupt; Claus Thamer; Martin Heni; Otto Tschritter; Jürgen Machann; Fritz Schick; Fausto Machicao; Hans-Ulrich Häring; Harald Staiger; Andreas Fritsche
Impact of variation near MC4R on whole-body fat distribution, liver fat, and weight loss.
Obesity (Silver Spring, Md.) 2009;17(10):1942-5.
2009: Karsten Müssig; Thomas Remer; Andreas Fritsche; Hans-Ulrich Häring; Christiane Maser-Gluth
Urinary free cortisone, but not cortisol, is associated with urine volume in severe obesity.
Steroids 2009;74(9):742-5.
2009: Martina Guthoff; Otto Tschritter; Daniela Berg; Inga Liepelt; Claudia Schulte; Fausto Machicao; HU Haering; Andreas Fritsche
Effect of genetic variation in Kv1.3 on olfactory function.
Diabetes/metabolism research and reviews 2009;25(6):523-7.
2009: Karsten Müssig; Harald Staiger; Fausto Machicao; Jürgen Machann; Anita M Hennige; Fritz Schick; Claus D Claussen; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan
AHSG gene variation is not associated with regional body fat distribution--a magnetic resonance study.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(8):432-7.
2009: Konstantinos Kantartzis; Claus Thamer; A Peter; Jürgen Machann; Fritz Schick; C Schraml; A Königsrainer; I Königsrainer; S Kröber; Andreas Niess; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan
High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease.
Gut 2009;58(9):1281-8.
2009: Karsten Müssig; Harald Staiger; Fausto Machicao; Kerstin Kirchhoff; Martina Guthoff; Silke A Schäfer; Konstantinos Kantartzis; Günther Silbernagel; Norbert Stefan; Jens J Holst; Baptist Gallwitz; Hans-Ulrich Häring; Andreas Fritsche
Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.
Diabetes 2009;58(7):1715-20.
2009: Michael Boettcher; Jürgen Machann; Norbert Stefan; Claus Thamer; Hans-Ulrich Häring; Claus D Claussen; Andreas Fritsche; Fritz Schick
Intermuscular adipose tissue (IMAT): association with other adipose tissue compartments and insulin sensitivity.
Journal of magnetic resonance imaging : JMRI 2009;29(6):1340-5.
2009: Silke A Schäfer; K Müssig; Harald Staiger; Fausto Machicao; Norbert Stefan; Baptist Gallwitz; Hans-Ulrich Häring; Andreas Fritsche
A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion.
Diabetologia 2009;52(6):1075-82.
2009: Axel Haupt; Martina Guthoff; Silke A Schäfer; Kerstin Kirchhoff; Fausto Machicao; Baptist Gallwitz; Harald Staiger; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring
The inhibitory effect of recent type 2 diabetes risk loci on insulin secretion is modulated by insulin sensitivity.
The Journal of clinical endocrinology and metabolism 2009;94(5):1775-80.
2009: Karsten Müssig; Harald Staiger; Fausto Machicao; Claus Thamer; Jürgen Machann; Fritz Schick; Claus D Claussen; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring
RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study.
Metabolism: clinical and experimental 2009;58(4):519-24.
2009: Axel Haupt; Claus Thamer; Harald Staiger; Otto Tschritter; K Kirchhoff; Fausto Machicao; Hans-Ulrich Häring; Norbert Stefan; Andreas Fritsche
Variation in the FTO gene influences food intake but not energy expenditure.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(4):194-7.
2009: Axel Haupt; Harald Staiger; Silke A Schäfer; K Kirchhoff; M Guthoff; Fausto Machicao; Baptist Gallwitz; Norbert Stefan; Hans-Ulrich Häring; Andreas Fritsche
The risk allele load accelerates the age-dependent decline in beta cell function.
Diabetologia 2009;52(3):457-62.
2009: Konstantinos Kantartzis; Fausto Machicao; Jürgen Machann; Fritz Schick; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan
The DGAT2 gene is a candidate for the dissociation between fatty liver and insulin resistance in humans.
Clinical science (London, England : 1979) 2009;116(6):531-7.
2009: Christoph Laske; Elke Stransky; Andreas Fritsche; Gerhard W Eschweiler; Thomas Leyhe
Inverse association of cortisol serum levels with T-tau, P-tau 181 and P-tau 231 peptide levels and T-tau/Abeta 1-42 ratios in CSF in patients with mild Alzheimer's disease dementia.
European archives of psychiatry and clinical neuroscience 2009;259(2):80-5.
2009: G Silbernagel; Norbert Stefan; M M Hoffmann; F Machicao-Arano; Jürgen Machann; Fritz Schick; B R Winkelmann; Bernhard O Boehm; Hans-Ulrich Häring; Andreas Fritsche; W März
The L162V polymorphism of the peroxisome proliferator activated receptor alpha gene (PPARA) is not associated with type 2 diabetes, BMI or body fat composition.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(3):113-8.
2009: Konstantinos Kantartzis; Harald Staiger; Jürgen Machann; Fritz Schick; Claus D Claussen; Fausto Machicao; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan
Adiponectin oligomers and ectopic fat in liver and skeletal muscle in humans.
Obesity (Silver Spring, Md.) 2009;17(2):390-2.
2009: Peter Weyrich; S Albet; Reiner Lammers; Fausto Machicao; Andreas Fritsche; Norbert Stefan; Hans-Ulrich Häring
Genetic variability of procolipase associates with altered insulin secretion in non-diabetic Caucasians.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(2):83-7.
2009: Peter Weyrich; Harald Staiger; Alena Stancáková; Silke A Schäfer; Kerstin Kirchhoff; Susanne Ullrich; Felicia Ranta; Baptist Gallwitz; Norbert Stefan; Fausto Machicao; Johanna Kuusisto; Markku Laakso; Andreas Fritsche; Hans-Ulrich Häring
Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced beta-cell function in non-diabetic subjects.
BMC medical genetics 2009;10():77.
2009: Katrin E Giel; Paul Enck; Stephan Zipfel; Markus Schrauth; Anna Bury; Marjo Graf; Sabine Kümmerle; Martina Guthoff; Norbert Stefan; Hans-Ulrich Häring; Andreas Fritsche
Psychological effects of prevention: do participants of a type 2 diabetes prevention program experience increased mental distress?
Diabetes/metabolism research and reviews 2009;25(1):83-8.
2009: Harald Staiger; J Wöll; Carina Haas; Fausto Machicao; Erwin D Schleicher; Andreas Fritsche; Norbert Stefan; Hans-Ulrich Häring
Selective association of plasma non-esterified fatty acid species with circulating interleukin-8 concentrations in humans.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(1):21-7.
2009: Otto Tschritter; Anita M Hennige; Hubert Preissl; Y Grichisch; K Kirchhoff; Konstantinos Kantartzis; Fausto Machicao; Andreas Fritsche; Hans-Ulrich Häring
Insulin effects on beta and theta activity in the human brain are differentially affected by ageing.
Diabetologia 2009;52(1):169-71.
2008: Nina F Schwenzer; Jürgen Machann; Michael M Haap; Petros Martirosian; Christina Schraml; Gerd Liebig; Norbert Stefan; Hans-Ulrich Häring; Claus D Claussen; Andreas Fritsche; Fritz Schick
T2* relaxometry in liver, pancreas, and spleen in a healthy cohort of one hundred twenty-nine subjects-correlation with age, gender, and serum ferritin.
Investigative radiology 2008;43(12):854-60.
2008: Kilian Rittig; K Staib; Jürgen Machann; M Böttcher; A Peter; Fritz Schick; Claus D Claussen; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring; Bernd M Balletshofer
Perivascular fatty tissue at the brachial artery is linked to insulin resistance but not to local endothelial dysfunction.
Diabetologia 2008;51(11):2093-9.
2008: Norbert Stefan; Andreas Fritsche; Cornelia Weikert; Heiner Boeing; Hans-Georg Joost; Hans-Ulrich Häring; Matthias B Schulze
Plasma fetuin-A levels and the risk of type 2 diabetes.
Diabetes 2008;57(10):2762-7.
2008: Norbert Stefan; Konstantinos Kantartzis; Jürgen Machann; Fritz Schick; Claus Thamer; Kilian Rittig; Bernd M Balletshofer; Fausto Machicao; Andreas Fritsche; Hans-Ulrich Häring
Identification and characterization of metabolically benign obesity in humans.
Archives of internal medicine 2008;168(15):1609-16.
2008: Andreas Fritsche
[Long acting insulin analogues: results of clinical studies with insulin glargine].
Deutsche medizinische Wochenschrift (1946) 2008;133 Suppl 4():S101-5; discussion S124-6.
2008: Axel Haupt; Claus Thamer; Jürgen Machann; Kerstin Kirchhoff; Norbert Stefan; Otto Tschritter; Fausto Machicao; Fritz Schick; Hans-Ulrich Häring; Andreas Fritsche
Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss.
Obesity (Silver Spring, Md.) 2008;16(8):1969-72.
2008: Karsten Müssig; Thomas Remer; Axel Haupt; Baptist Gallwitz; Andreas Fritsche; Hans-Ulrich Häring; Christiane Maser-Gluth
11beta-hydroxysteroid dehydrogenase 2 activity is elevated in severe obesity and negatively associated with insulin sensitivity.
Obesity (Silver Spring, Md.) 2008;16(6):1256-60.
2008: Kilian Rittig; Andreas Peter; Katrin M Baltz; Otto Tschritter; Cora Weigert; Francesco Andreozzi; Francesco Perticone; Dorothea Siegel-Axel; Norbert Stefan; Andreas Fritsche; Helmut R Salih; Erwin Schleicher; Fausto Machicao; Giorgio Sesti; Hans-Ulrich Häring; Bernd M Balletshofer
The CCR2 promoter polymorphism T-960A, but not the serum MCP-1 level, is associated with endothelial function in prediabetic individuals.
Atherosclerosis 2008;198(2):338-46.
2008: Harald Staiger; Fausto Machicao; Roman Werner; Alke Guirguis; Melanie Weisser; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring
Genetic variation within the ANGPTL4 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus.
Metabolism: clinical and experimental 2008;57(5):637-43.
2008: Nina F Schwenzer; Jürgen Machann; Petros Martirosian; Norbert Stefan; Christina Schraml; Andreas Fritsche; Claus D Claussen; Fritz Schick
Quantification of pancreatic lipomatosis and liver steatosis by MRI: comparison of in/opposed-phase and spectral-spatial excitation techniques.
Investigative radiology 2008;43(5):330-7.
2008: Norbert Stefan; A Peter; Alexander Cegan; Harald Staiger; Jürgen Machann; Fritz Schick; Claus D Claussen; Andreas Fritsche; Hans-Ulrich Häring; Erwin Schleicher
Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans.
Diabetologia 2008;51(4):648-56.
2008: K Kirchhoff; Fausto Machicao; Axel Haupt; Silke A Schäfer; Otto Tschritter; Harald Staiger; Norbert Stefan; Hans-Ulrich Häring; Andreas Fritsche
Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.
Diabetologia 2008;51(4):597-601.
2008: Claus Thamer; Jürgen Machann; Norbert Stefan; Silke A Schäfer; Fausto Machicao; Harald Staiger; Markku Laakso; Michael Böttcher; Claus Claussen; Fritz Schick; Andreas Fritsche; Hans-Ulrich Haring
Variations in PPARD determine the change in body composition during lifestyle intervention: a whole-body magnetic resonance study.
The Journal of clinical endocrinology and metabolism 2008;93(4):1497-500.
2008: Konstantinos Kantartzis; Kilian Rittig; Alexander Cegan; Jürgen Machann; Fritz Schick; Bernd M Balletshofer; Andreas Fritsche; Erwin Schleicher; Hans-Ulrich Häring; Norbert Stefan
Fatty liver is independently associated with alterations in circulating HDL2 and HDL3 subfractions.
Diabetes care 2008;31(2):366-8.
2008: Peter Weyrich; Fausto Machicao; Julia Reinhardt; Jürgen Machann; Fritz Schick; Otto Tschritter; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring
SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention--the TULIP Study.
BMC medical genetics 2008;9():100.
2008: Björn Friedrich; Peter Weyrich; Alena Stancáková; Jianjung Wang; Johanna Kuusisto; Markku Laakso; Giorgio Sesti; Elena Succurro; Ulf Smith; Torben Hansen; Oluf Pedersen; Fausto Machicao; Silke Schäfer; Florian Lang; Teut Risler; Susanne Ullrich; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring
Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.
PloS one 2008;3(11):e3506.
2008: Harald Staiger; Fausto Machicao; Konstantinos Kantartzis; Silke A Schäfer; Kerstin Kirchhoff; Martina Guthoff; Günther Silbernagel; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring
Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.
PloS one 2008;3(8):e3019.
2008: Anita M Hennige; Harald Staiger; Corinna Wicke; Fausto Machicao; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan
Fetuin-A induces cytokine expression and suppresses adiponectin production.
PloS one 2008;3(3):e1765.
2008: Kilian Rittig; K Holder; Jan Stock; Otto Tschritter; A Peter; Norbert Stefan; Andreas Fritsche; Fausto Machicao; Hans-Ulrich Häring; Bernd M Balletshofer
Endothelial NO-synthase intron 4 polymorphism is associated with disturbed in vivo nitric oxide production in individuals prone to type 2 diabetes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(1):13-7.
2007: Otto Tschritter; Hubert Preissl; Y Yokoyama; Fausto Machicao; Hans-Ulrich Häring; Andreas Fritsche
Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans.
Diabetologia 2007;50(12):2602-3.
2007: Silke A Schäfer; Otto Tschritter; Fausto Machicao; Claus Thamer; Norbert Stefan; Baptist Gallwitz; J J Holst; J M Dekker; L M 't Hart; L M t'Hart; G Nijpels; Timon W van Haeften; Hans-Ulrich Häring; Andreas Fritsche
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.
Diabetologia 2007;50(12):2443-50.
2007: Peter Weyrich; Fausto Machicao; Harald Staiger; P Simon; Claus Thamer; Jürgen Machann; Fritz Schick; Alke Guirguis; Andreas Fritsche; Norbert Stefan; Hans-Ulrich Häring
Role of AMP-activated protein kinase gamma 3 genetic variability in glucose and lipid metabolism in non-diabetic whites.
Diabetologia 2007;50(10):2097-106.
2007: Norbert Stefan; Anita M Hennige; Harald Staiger; Erwin Schleicher; Andreas Fritsche; Hans-Ulrich Häring
Circulating retinol-binding protein-4, insulin sensitivity, insulin secretion, and insulin disposition index in obese and nonobese subjects: response to Broch et al.
Diabetes care 2007;30(8):e91; author reply e92.
2007: Harald Staiger; Fausto Machicao; Jürgen Machann; Fritz Schick; T Kuulasmaa; M Laakso; Andreas Fritsche; Norbert Stefan; Hans-Ulrich Häring
Genetic variation within the APPL locus is not associated with metabolic or inflammatory traits in a healthy White population.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(8):817-22.
2007: Silke Schäfer; Konstantinos Kantartzis; Jürgen Machann; C Venter; Andreas Niess; Fritz Schick; Fausto Machicao; Hans-Ulrich Häring; Andreas Fritsche; Norbert Stefan
Lifestyle intervention in individuals with normal versus impaired glucose tolerance.
European journal of clinical investigation 2007;37(7):535-43.
2007: Kilian Rittig; Claus Thamer; Fausto Machicao; R Rietig; Norbert Stefan; Andreas Fritsche; Hans-Ulrich Haring; Bernd M Balletshofer
The Pro12Ala polymorphism in PPARG2 increases the effectiveness of primary prevention of cardiovascular disease by a lifestyle intervention.
Diabetologia 2007;50(6):1345-7.
2007: Norbert Stefan; Anita M Hennige; Harald Staiger; Jürgen Machann; Fritz Schick; Erwin Schleicher; Andreas Fritsche; Hans-Ulrich Häring
High circulating retinol-binding protein 4 is associated with elevated liver fat but not with total, subcutaneous, visceral, or intramyocellular fat in humans.
Diabetes care 2007;30(5):1173-8.
2007: Claus Thamer; Jürgen Machann; Norbert Stefan; Michael Haap; Silke Schäfer; Sonja Brenner; Konstantinos Kantartzis; Claus Claussen; Fritz Schick; Hans-Ulrich Haring; Andreas Fritsche
High visceral fat mass and high liver fat are associated with resistance to lifestyle intervention.
Obesity (Silver Spring, Md.) 2007;15(2):531-8.
2007: Peter Weyrich; Norbert Stefan; Hans-Ulrich Häring; Markku Laakso; Andreas Fritsche
Effect of genotype on success of lifestyle intervention in subjects at risk for type 2 diabetes.
Journal of molecular medicine (Berlin, Germany) 2007;85(2):107-17.
2007: Otto Tschritter; Anita M Hennige; Hubert Preissl; Katarina Porubska; Silke A Schäfer; Werner Lutzenberger; Fausto Machicao; Niels Birbaumer; Andreas Fritsche; Hans-Ulrich Häring
Cerebrocortical beta activity in overweight humans responds to insulin detemir.
PloS one 2007;2(11):e1196.
2007: Harald Staiger; Fausto Machicao; Norbert Stefan; Otto Tschritter; Claus Thamer; Konstantinos Kantartzis; Silke A Schäfer; Kerstin Kirchhoff; Andreas Fritsche; Hans-Ulrich Häring
Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.
PloS one 2007;2(9):e832.
2007: Konstantinos Kantartzis; Andreas Fritsche; Fausto Machicao; Michael Stumvoll; Jürgen Machann; Fritz Schick; Hans-Ulrich Häring; Norbert Stefan
Upstream transcription factor 1 gene polymorphisms are associated with high antilipolytic insulin sensitivity and show gene-gene interactions.
Journal of molecular medicine (Berlin, Germany) 2007;85(1):55-61.
2006: Konstantinos Kantartzis; Kilian Rittig; Bernd M Balletshofer; Jürgen Machann; Fritz Schick; Katarina Porubska; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan
The relationships of plasma adiponectin with a favorable lipid profile, decreased inflammation, and less ectopic fat accumulation depend on adiposity.
Clinical chemistry 2006;52(10):1934-42.
2006: Katarína Porubská; Ralf Veit; Hubert Preissl; Andreas Fritsche; Niels Birbaumer
Subjective feeling of appetite modulates brain activity: an fMRI study.
NeuroImage 2006;32(3):1273-80.
2006: Otto Tschritter; Hubert Preissl; Anita M Hennige; Michael Stumvoll; Katarina Porubska; Rebekka Frost; Hannah Marx; Benjamin Klösel; Werner Lutzenberger; Niels Birbaumer; Hans-Ulrich Häring; Andreas Fritsche
The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: a magnetoencephalographic study.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(32):12103-8.
2006: Silke A Schäfer; Karsten Müssig; Norbert Stefan; Hans-Ulrich Häring; Andreas Fritsche; Bernd M Balletshofer
Plasma homocysteine concentrations in young individuals at increased risk of type 2 diabetes are associated with subtle differences in glomerular filtration rate but not with insulin resistance.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2006;114(6):306-9.
2006: Anita M Hennige; T Sartorius; Otto Tschritter; Hubert Preissl; Andreas Fritsche; P Ruth; Hans-Ulrich Häring
Tissue selectivity of insulin detemir action in vivo.
Diabetologia 2006;49(6):1274-82.
2006: Michael Haap; Emanuela Heller; Claus Thamer; Otto Tschritter; Norbert Stefan; Andreas Fritsche
Association of serum phosphate levels with glucose tolerance, insulin sensitivity and insulin secretion in non-diabetic subjects.
European journal of clinical nutrition 2006;60(6):734-9.
2006: Norbert Stefan; Anita M Hennige; Harald Staiger; Jürgen Machann; Fritz Schick; Stefan Kröber; Fausto Machicao; Andreas Fritsche; Hans-Ulrich Häring
Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans.
Diabetes care 2006;29(4):853-7.
2006: Jürgen Machann; Claus Thamer; Birgit Schnoedt; Norbert Stefan; Hans-Ulrich Haring; Claus D Claussen; Andreas Fritsche; Fritz Schick
Hepatic lipid accumulation in healthy subjects: a comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;55(4):913-7.
2006: Claus Thamer; Michael Haap; Emanuela Heller; L Joel; S Braun; Otto Tschritter; Hans-Ulrich Haring; Andreas Fritsche
Beta cell function, insulin resistance and plasma adiponectin concentrations are predictors for the change of postprandial glucose in non-diabetic subjects at risk for type 2 diabetes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(3):178-82.
2006: Konstantinos Kantartzis; Andreas Fritsche; Fausto Machicao; Hans-Ulrich Häring; Norbert Stefan
The -8503 G/A polymorphism of the adiponectin receptor 1 gene is associated with insulin sensitivity dependent on adiposity.
Diabetes care 2006;29(2):464.
2006: Otto Tschritter; Fausto Machicao; Norbert Stefan; Silke Schäfer; Cora Weigert; Harald Staiger; Christian Spieth; Hans-Ulrich Häring; Andreas Fritsche
A new variant in the human Kv1.3 gene is associated with low insulin sensitivity and impaired glucose tolerance.
The Journal of clinical endocrinology and metabolism 2006;91(2):654-8.
2005: Katrin Staiger; Norbert Stefan; Harald Staiger; Mathias D Brendel; D Brandhorst; Reinhard Bretzel; Fausto Machicao; Monika Kellerer; Michael Stumvoll; Andreas Fritsche; Hans-Ulrich Häring
Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis.
The Journal of clinical endocrinology and metabolism 2005;90(12):6707-13.
2005: Norbert Stefan; Fausto Machicao; Harald Staiger; Jürgen Machann; Fritz Schick; Otto Tschritter; Christian Spieth; Cora Weigert; Andreas Fritsche; Michael Stumvoll; Hans-Ulrich Häring
Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.
Diabetologia 2005;48(11):2282-91.
2005: Konstantinos Kantartzis; Andreas Fritsche; Otto Tschritter; Claus Thamer; Michael Haap; Silke Schäfer; Michael Stumvoll; Hans-Ulrich Häring; Norbert Stefan
The association between plasma adiponectin and insulin sensitivity in humans depends on obesity.
Obesity research 2005;13(10):1683-91.
2005: Jürgen Machann; Claus Thamer; Birgit Schnoedt; Norbert Stefan; Michael Stumvoll; Hans-Ulrich Haring; Claus D Claussen; Andreas Fritsche; Fritz Schick
Age and gender related effects on adipose tissue compartments of subjects with increased risk for type 2 diabetes: a whole body MRI/MRS study.
Magma (New York, N.Y.) 2005;18(3):128-37.
2005: Norbert Stefan; Silke Schäfer; Fausto Machicao; Jürgen Machann; Fritz Schick; Claus D Claussen; Michael Stumvoll; Hans-Ulrich Häring; Andreas Fritsche
Liver fat and insulin resistance are independently associated with the -514C>T polymorphism of the hepatic lipase gene.
The Journal of clinical endocrinology and metabolism 2005;90(7):4238-43.
2005: Michael Haap; Fausto Machicao; Norbert Stefan; Claus Thamer; Otto Tschritter; F Schnuck; Diethelm Wallwiener; Michael Stumvoll; Hans-Ulrich Häring; Andreas Fritsche
Genetic determinants of insulin action in polycystic ovary syndrome.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2005;113(5):275-81.
2005: Claus Thamer; Otto Tschritter; Michael Haap; Fatemeh Shirkavand; Jürgen Machann; Andreas Fritsche; Fritz Schick; Hans-Ulrich Häring; Michael Stumvoll
Elevated serum GGT concentrations predict reduced insulin sensitivity and increased intrahepatic lipids.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37(4):246-51.
2005: Jürgen Machann; Claus Thamer; Birgit Schnoedt; Michael Haap; Hans-Ulrich Haring; Claus D Claussen; Michael Stumvoll; Andreas Fritsche; Fritz Schick
Standardized assessment of whole body adipose tissue topography by MRI.
Journal of magnetic resonance imaging : JMRI 2005;21(4):455-62.
2005: Peter Weyrich; Reiner Lammers; Andreas Fritsche; Fausto Machicao; Hans-Ulrich Häring; Norbert Stefan
A novel functional polymorphism (-336A/G) in the promoter of the partitioning-defective protein-6alpha gene is associated with increased glucose tolerance and lower concentrations of serum non-esterified fatty acids.
Diabetologia 2005;48(4):669-74.
2005: Cora Weigert; Claus Thamer; Katrin Brodbeck; Alke Guirguis; Fausto Machicao; Jürgen Machann; Fritz Schick; Michael Stumvoll; Andreas Fritsche; Hans-Ulrich Häring; Erwin D Schleicher
The -913 G/A glutamine:fructose-6-phosphate aminotransferase gene polymorphism is associated with measures of obesity and intramyocellular lipid content in nondiabetic subjects.
The Journal of clinical endocrinology and metabolism 2005;90(3):1639-43.
2005: Norbert Stefan; Jürgen Machann; Fritz Schick; Claus D Claussen; Claus Thamer; Andreas Fritsche; Hans-Ulrich Häring
New imaging techniques of fat, muscle and liver within the context of determining insulin sensitivity.
Hormone research 2005;64 Suppl 3():38-44.
2004: Claus Thamer; Jürgen Machann; Michael Haap; Norbert Stefan; Emanuela Heller; Birgit Schnödt; Michael Stumvoll; Claus Claussen; Andreas Fritsche; Fritz Schick; Hans-Ulrich Häring
Intrahepatic lipids are predicted by visceral adipose tissue mass in healthy subjects.
Diabetes care 2004;27(11):2726-9.
2004: Harald Staiger; Simone Kaltenbach; Katrin Staiger; Norbert Stefan; Andreas Fritsche; Alke Guirguis; Claudia Péterfi; Melanie Weisser; Fausto Machicao; Michael Stumvoll; Hans-Ulrich Häring
Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism.
Diabetes 2004;53(9):2195-201.
2004: Andreas Fritsche; Hans-Ulrich Häring
At last, a weight neutral insulin?
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2004;28 Suppl 2():S41-6.
2004: Claus Thamer; Michael Haap; Oliver Bachmann; T Zur Nieden; Otto Tschritter; Norbert Stefan; Andreas Fritsche; Stephan Jacob; Michael Stumvoll; Hans-Ulrich Häring
Serum adiponectin levels predict the effect of short-term dietary interventions on insulin sensitivity in humans.
Diabetologia 2004;47(7):1303-5.
2004: Fausto Machicao; Harald Staiger; Andreas Fritsche; Alke Guirguis; Melanie Weisser; Michael Stumvoll; Hans-Ulrich Häring
Association of the -514C-->T polymorphism in the hepatic lipase gene (LIPC) promoter with elevated fasting insulin concentrations, but not insulin resistance, in non-diabetic Germans.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(5):303-6.
2004: Michael Stumvoll; Andreas Fritsche; L M t'Hart; Jürgen Machann; Claus Thamer; Otto Tschritter; Timon W van Haeften; Stephan Jacob; J M Dekker; J A Maassen; Fausto Machicao; Fritz Schick; R J Heine; Hans-Ulrich Häring
The Gly482Ser variant in the peroxisome proliferator-activated receptor gamma coactivator-1 is not associated with diabetes-related traits in non-diabetic German and Dutch populations.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2004;112(5):253-7.
2004: Claus Thamer; Jürgen Machann; Michael Haap; Oliver Bachmann; Beate Wietek; Dominik Dahl; Otto Tschritter; Andreas Fritsche; Stephan Jacob; Fritz Schick; Michael Stumvoll; Hans-Ulrich Häring
[Reduced insulin effect in subclinical fatty liver].
Deutsche medizinische Wochenschrift (1946) 2004;129(16):872-5.
2004: Norbert Stefan; Michael Stumvoll; Fausto Machicao; Matthias Koch; Hans-Ulrich Häring; Andreas Fritsche
C825T polymorphism of the G protein beta3 subunit is associated with obesity but not with insulin sensitivity.
Obesity research 2004;12(4):679-83.
2004: Andreas Fritsche; Hans-Ulrich Häring; Michael Stumvoll
[White blood cell count as a predictor of glucose tolerance and insulin sensitivity. The role of inflammation in the pathogenesis of type 2 diabetes mellitus].
Deutsche medizinische Wochenschrift (1946) 2004;129(6):244-8.
2003: Michael Stumvoll; Hans-Ulrich Häring; Andreas Fritsche
For debate: Starling's curve of the pancreas--overuse of a concept?
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2003;35(7):391-5.
2003: Claus Thamer; Michael Stumvoll; Andreas Niess; Otto Tschritter; Michael Haap; Regine Becker; Fatemeh Shirkavand; Oliver Bachmann; Kristian Rett; Annette Volk; Hans-Ulrich Häring; Andreas Fritsche
Reduced skeletal muscle oxygen uptake and reduced beta-cell function: two early abnormalities in normal glucose-tolerant offspring of patients with type 2 diabetes.
Diabetes care 2003;26(7):2126-32.
2003: Andreas Fritsche; Matthias Axel Schweitzer; Hans-Ulrich Häring
Glimepiride combined with morning insulin glargine, bedtime neutral protamine hagedorn insulin, or bedtime insulin glargine in patients with type 2 diabetes. A randomized, controlled trial.
Annals of internal medicine 2003;138(12):952-9.
2003: Otto Tschritter; Andreas Fritsche; Norbert Stefan; Michael Haap; Claus Thamer; Oliver Bachmann; Dominik Dahl; Elke Maerker; Anna Teigeler; Fausto Machicao; Hans-Ulrich Häring; Michael Stumvoll
Increased insulin clearance in peroxisome proliferator-activated receptor gamma2 Pro12Ala.
Metabolism: clinical and experimental 2003;52(6):778-83.
2003: Andreas Fritsche; Michael Stumvoll; Hans-Ulrich Häring
[Insulin secretion and aging. Implications for insulin therapy in the geriatric patient with diabetes mellitus].
Medizinische Klinik (Munich, Germany : 1983) 2003;98(5):287-91.
2003: Claus Thamer; Jürgen Machann; Oliver Bachmann; Michael Haap; Dominik Dahl; Beate Wietek; Otto Tschritter; Andreas Niess; Klaus Brechtel; Andreas Fritsche; Claus Claussen; Stephan Jacob; Fritz Schick; Hans-Ulrich Häring; Michael Stumvoll
Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity.
The Journal of clinical endocrinology and metabolism 2003;88(4):1785-91.
2003: Otto Tschritter; Andreas Fritsche; Fatemeh Shirkavand; Fausto Machicao; Hans-Ulrich Häring; Michael Stumvoll
Assessing the shape of the glucose curve during an oral glucose tolerance test.
Diabetes care 2003;26(4):1026-33.
2003: Harald Staiger; Otto Tschritter; Jürgen Machann; Claus Thamer; Andreas Fritsche; Elke Maerker; Fritz Schick; Hans-Ulrich Häring; Michael Stumvoll
Relationship of serum adiponectin and leptin concentrations with body fat distribution in humans.
Obesity research 2003;11(3):368-72.
2003: Otto Tschritter; Andreas Fritsche; Claus Thamer; Michael Haap; Fatemeh Shirkavand; Stefanie Rahe; Harald Staiger; Elke Maerker; Hans-Ulrich Häring; Michael Stumvoll
Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism.
Diabetes 2003;52(2):239-43.
2002: Claus Thamer; Jürgen Machann; Otto Tschritter; Michael Haap; Beate Wietek; Dominik Dahl; Oliver Bachmann; Andreas Fritsche; Stephan Jacob; Michael Stumvoll; Fritz Schick; Hans-Ulrich Häring
Relationship between serum adiponectin concentration and intramyocellular lipid stores in humans.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(11-12):646-9.
2002: Andreas Fritsche; Otto Tschritter; Hans-Ulrich Häring; John E Gerich; Michael Stumvoll
The role of beta-adrenergic sensitivity in the pathogenesis of hypoglycaemia unawareness.
Diabetes, nutrition & metabolism 2002;15(5):357-61; discussion 361-2.
2002: Otto Tschritter; Michael Stumvoll; Fausto Machicao; Martin Holzwarth; Melanie Weisser; Elke Maerker; Anna Teigeler; Hans-Ulrich Häring; Andreas Fritsche
The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia.
Diabetes 2002;51(9):2854-60.
2002: Andreas Fritsche; Alexander Madaus; Norbert Stefan; Otto Tschritter; Elke Maerker; Anna Teigeler; Hans-Ulrich Häring; Michael Stumvoll
Relationships among age, proinsulin conversion, and beta-cell function in nondiabetic humans.
Diabetes 2002;51 Suppl 1():S234-9.
2002: Michael Stumvoll; Andreas Fritsche; Hans-Ulrich Häring
Clinical characterization of insulin secretion as the basis for genetic analyses.
Diabetes 2002;51 Suppl 1():S122-9.
2002: Anita M Hennige; Andreas Fritsche; Volker Strack; Cora Weigert; Mischak Harald; Patricia Borboni; Walter Renn; Hans-Ulrich Häring; Monika Kellerer
PKC zeta enhances insulin-like growth factor 1-dependent mitogenic activity in the rat clonal beta cell line RIN 1046-38.
Biochemical and biophysical research communications 2002;290(1):85-90.
2002: Michael Stumvoll; Norbert Stefan; Andreas Fritsche; Alexander Madaus; Otto Tschritter; Matthias Koch; Fausto Machicao; Hans-Ulrich Häring
Interaction effect between common polymorphisms in PPARgamma2 (Pro12Ala) and insulin receptor substrate 1 (Gly972Arg) on insulin sensitivity.
Journal of molecular medicine (Berlin, Germany) 2002;80(1):33-8.
2002: Michael Stumvoll; Otto Tschritter; Andreas Fritsche; Harald Staiger; Walter Renn; Melanie Weisser; Fausto Machicao; Hans-Ulrich Häring
Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes.
Diabetes 2002;51(1):37-41.
2001: Andreas Fritsche; Alexander Madaus; Walter Renn; Otto Tschritter; Anna Teigeler; Melanie Weisser; Elke Maerker; Fausto Machicao; Hans-Ulrich Häring; Michael Stumvoll
The prevalent Gly1057Asp polymorphism in the insulin receptor substrate-2 gene is not associated with impaired insulin secretion.
The Journal of clinical endocrinology and metabolism 2001;86(10):4822-5.
2001: Monika Kellerer; Reiner Lammers; Andreas Fritsche; Volker Strack; Fausto Machicao; P Borboni; Axel Ullrich; Hans-Ulrich Häring
Insulin inhibits leptin receptor signalling in HEK293 cells at the level of janus kinase-2: a potential mechanism for hyperinsulinaemia-associated leptin resistance.
Diabetologia 2001;44(9):1125-32.
2001: Michael Stumvoll; Andreas Fritsche; Alexander Madaus; Norbert Stefan; Melanie Weisser; Fausto Machicao; Hans-Ulrich Häring
Functional significance of the UCSNP-43 polymorphism in the CAPN10 gene for proinsulin processing and insulin secretion in nondiabetic Germans.
Diabetes 2001;50(9):2161-3.
2001: Norbert Stefan; Hans Günther Wahl; Andreas Fritsche; Hans-Ulrich Häring; Michael Stumvoll
Effect of the pattern of elevated free fatty acids on insulin sensitivity and insulin secretion in healthy humans.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2001;33(7):432-8.
2001: Andreas Fritsche; Alexander Madaus; Otto Tschritter; M Ozeker; E L Wulle; Fausto Machicao; Hans-Ulrich Häring; Michael Stumvoll
[Polymorphism of pro12Ala in peroxisome proliferator activated receptor gamma 2 (PPAgamma2): beta cell function and insulin sensitivity].
Deutsche medizinische Wochenschrift (1946) 2001;126(20):580-4.
2001: Michael Stumvoll; Andreas Fritsche; Hans-Ulrich Häring
The OGTT as test for beta cell function?
European journal of clinical investigation 2001;31(5):380-1.
2001: Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring; Michael Stumvoll
Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene.
Diabetes 2001;50(5):1143-8.
2001: Michael Stumvoll; Andreas Fritsche; Annette Volk; Norbert Stefan; Alexander Madaus; Elke Maerker; Anna Teigeler; Matthias Koch; Fausto Machicao; Hans-Ulrich Häring
The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans.
Diabetes 2001;50(4):882-5.
2001: Michael Stumvoll; Andreas Fritsche; Norbert Stefan; E Hardt; Hans-Ulrich Häring
Evidence against a rate-limiting role of proinsulin processing for maximal insulin secretion in subjects with impaired glucose tolerance and beta-cell dysfunction.
The Journal of clinical endocrinology and metabolism 2001;86(3):1235-9.
2001: Norbert Stefan; Andreas Fritsche; Hans-Ulrich Häring; Michael Stumvoll
Acute stimulation of leptin concentrations in humans during hyperglycemic hyperinsulinemia. Influence of free fatty acids and fasting.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(1):138-42.
2000: Norbert Stefan; Andreas Fritsche; Alexander Madaus; Hans-Ulrich Häring; Michael Stumvoll
Stimulatory effect of increased non-esterified fatty acid concentrations on proinsulin processing in healthy humans.
Diabetologia 2000;43(11):1368-73.
2000: Andreas Fritsche; Norbert Stefan; E Hardt; Hans-Ulrich Häring; Michael Stumvoll
Characterisation of beta-cell dysfunction of impaired glucose tolerance: evidence for impairment of incretin-induced insulin secretion.
Diabetologia 2000;43(7):852-8.
2000: Michael Stumvoll; Andreas Fritsche; Norbert Stefan; Hans-Ulrich Häring
A 60 minute hyperglycemic clamp is sufficient to assess both phases of insulin secretion.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2000;32(6):230-2.
2000: Andreas Fritsche; Norbert Stefan; E Hardt; S Schützenauer; Hans-Ulrich Häring; Michael Stumvoll
A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility.
European journal of clinical investigation 2000;30(5):411-8.
2000: Andreas Fritsche; RM Schmülling; Hans-Ulrich Häring; Michael Stumvoll
Intensive insulin therapy combined with metformin in obese type 2 diabetic patients.
Acta diabetologica 2000;37(1):13-8.
2000: Michael Stumvoll; Andreas Fritsche; Otto Tschritter; R Lehmann; Hans Günther Wahl; Walter Renn; Hans-Ulrich Häring
Leptin levels in humans are acutely suppressed by isoproterenol despite acipimox-induced inhibition of lipolysis, but not by free fatty acids.
Metabolism: clinical and experimental 2000;49(3):335-9.
2000: Andreas Fritsche; Michael Stumvoll; Hans-Ulrich Häring; John E Gerich
Reversal of hypoglycemia unawareness in a long-term type 1 diabetic patient by improvement of beta-adrenergic sensitivity after prevention of hypoglycemia.
The Journal of clinical endocrinology and metabolism 2000;85(2):523-5.
1999: Andreas Fritsche; Michael Stumvoll; S Goebbel; K M Reinauer; RM Schmülling; Hans-Ulrich Häring
Long term effect of a structured inpatient diabetes teaching and treatment programme in type 2 diabetic patients: influence of mode of follow-up.
Diabetes research and clinical practice 1999;46(2):135-41.
1998: Andreas Fritsche; Michael Stumvoll; M Grüb; S Sieslack; Walter Renn; RM Schmülling; Hans-Ulrich Häring; John E Gerich
Effect of hypoglycemia on beta-adrenergic sensitivity in normal and type 1 diabetic subjects.
Diabetes care 1998;21(9):1505-10.
1998: Andreas Fritsche; Michael Stumvoll; Walter Renn; RM Schmülling
Diabetes teaching program improves glycemic control and preserves perception of hypoglycemia.
Diabetes research and clinical practice 1998;40(2):129-35.
1998: Andreas Fritsche; Hans Günther Wahl; Elisabeth Metzinger; Walter Renn; Monika Kellerer; Hans-Ulrich Häring; Michael Stumvoll
Evidence for inhibition of leptin secretion by catecholamines in man.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1998;106(5):415-8.
1997: Michael Stumvoll; Andreas Fritsche
Necrotizing fasciitis caused by unencapsulated Haemophilus influenzae.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997;25(2):327.
1996: Michael Stumvoll; Andreas Fritsche; Manfred Wehrmann; Florian Dammann; H D Becker; M Eggstein
A functioning adrenocortical hemangioma.
The Journal of urology 1996;155(2):638.
1992: G Iser; Andreas Fritsche; M Eggstein
[MODY diabetes].
Deutsche medizinische Wochenschrift (1946) 1992;117(51-52):1985-6.