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Andreas Fritsche
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112
Häring, Hans-Ulrich
79
Stefan, Norbert
60
Machicao, Fausto
56
Stumvoll, Michael
42
Tschritter, Otto
42
Machann, Jürgen
41
Schick, Fritz
33
Thamer, Claus
32
Staiger, Harald
16
Kantartzis, Konstantinos
15
Haap, Michael
14
Claussen, Claus
14
Schäfer, Silke
12
Hennige, Anita
8
Gallwitz, Baptist
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All Publications
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2009: Müssig Karsten; Staiger Harald; Machicao Fausto; Machann Jürgen; Schick Fritz; Schäfer Silke A; Claussen Claus D; Holst Jens J; Gallwitz Baptist; Stefan Norbert; Fritsche Andreas; Häring Hans-Ulrich
Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus.
Metabolism: clinical and experimental 2009;58(12):1809-11.
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2009: Tschritter Otto; Preissl Hubert; Hennige Anita M; Sartorius Tina; Grichisch Yuko; Stefan Norbert; Guthoff Martina; Düsing Stephan; Machann Jürgen; Schleicher Erwin; Cegan Alexander; Birbaumer Niels; Fritsche Andreas; Häring Hans-Ulrich
The insulin effect on cerebrocortical theta activity is associated with serum concentrations of saturated nonesterified Fatty acids.
The Journal of clinical endocrinology and metabolism 2009;94(11):4600-7.
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2009: Kantartzis Konstantinos; Peter Andreas; Machicao Fausto; Machann Jürgen; Wagner Silvia; Königsrainer Ingmar; Königsrainer Alfred; Schick Fritz; Fritsche Andreas; Häring Hans-Ulrich; Stefan Norbert
Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene.
Diabetes 2009;58(11):2616-23.
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2009: Tschritter O; Schäfer S A; Klett J; Pfäfflin A; Häring H-U; Hennige A M; Fritsche A
Insulin detemir causes increased symptom awareness during hypoglycaemia compared to human insulin.
Diabetes, obesity & metabolism 2009;11(11):1017-26.
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2009: Haupt Axel; Thamer Claus; Heni Martin; Tschritter Otto; Machann Jürgen; Schick Fritz; Machicao Fausto; Häring Hans-Ulrich; Staiger Harald; Fritsche Andreas
Impact of variation near MC4R on whole-body fat distribution, liver fat, and weight loss.
Obesity (Silver Spring, Md.) 2009;17(10):1942-5.
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2009: Müssig Karsten; Remer Thomas; Fritsche Andreas; Häring Hans-Ulrich; Maser-Gluth Christiane
Urinary free cortisone, but not cortisol, is associated with urine volume in severe obesity.
Steroids 2009;74(9):742-5.
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2009: Guthoff Martina; Tschritter Otto; Berg Daniela; Liepelt Inga; Schulte Claudia; Machicao Fausto; Haering Hans-Ulrich; Fritsche Andreas
Effect of genetic variation in Kv1.3 on olfactory function.
Diabetes/metabolism research and reviews 2009;25(6):523-7.
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2009: Müssig K; Staiger H; Machicao F; Machann J; Hennige A M; Schick F; Claussen C D; Fritsche A; Häring H-U; Stefan N
AHSG gene variation is not associated with regional body fat distribution--a magnetic resonance study.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(8):432-7.
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2009: Kantartzis K; Thamer C; Peter A; Machann J; Schick F; Schraml C; Königsrainer A; Königsrainer I; Kröber S; Niess A; Fritsche A; Häring H-U; Stefan N
High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease.
Gut 2009;58(9):1281-8.
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2009: Müssig Karsten; Staiger Harald; Machicao Fausto; Kirchhoff Kerstin; Guthoff Martina; Schäfer Silke A; Kantartzis Konstantinos; Silbernagel Günther; Stefan Norbert; Holst Jens J; Gallwitz Baptist; Häring Hans-Ulrich; Fritsche Andreas
Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.
Diabetes 2009;58(7):1715-20.
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2009: Boettcher Michael; Machann Jürgen; Stefan Norbert; Thamer Claus; Häring Hans-Ulrich; Claussen Claus D; Fritsche Andreas; Schick Fritz
Intermuscular adipose tissue (IMAT): association with other adipose tissue compartments and insulin sensitivity.
Journal of magnetic resonance imaging : JMRI 2009;29(6):1340-5.
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2009: Schäfer S A; Müssig K; Staiger H; Machicao F; Stefan N; Gallwitz B; Häring H U; Fritsche A
A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion.
Diabetologia 2009;52(6):1075-82.
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2009: Haupt Axel; Guthoff Martina; Schäfer Silke A; Kirchhoff Kerstin; Machicao Fausto; Gallwitz Baptist; Staiger Harald; Stefan Norbert; Fritsche Andreas; Häring Hans-Ulrich
The inhibitory effect of recent type 2 diabetes risk loci on insulin secretion is modulated by insulin sensitivity.
The Journal of clinical endocrinology and metabolism 2009;94(5):1775-80.
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2009: Müssig Karsten; Staiger Harald; Machicao Fausto; Thamer Claus; Machann Jürgen; Schick Fritz; Claussen Claus D; Stefan Norbert; Fritsche Andreas; Häring Hans-Ulrich
RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study.
Metabolism: clinical and experimental 2009;58(4):519-24.
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2009: Haupt A; Thamer C; Staiger H; Tschritter O; Kirchhoff K; Machicao F; Häring H-U; Stefan N; Fritsche A
Variation in the FTO gene influences food intake but not energy expenditure.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(4):194-7.
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2009: Haupt A; Staiger H; Schäfer S A; Kirchhoff K; Guthoff M; Machicao F; Gallwitz B; Stefan N; Häring H-U; Fritsche A
The risk allele load accelerates the age-dependent decline in beta cell function.
Diabetologia 2009;52(3):457-62.
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2009: Kantartzis Konstantinos; Machicao Fausto; Machann Jürgen; Schick Fritz; Fritsche Andreas; Häring Hans-Ulrich; Stefan Norbert
The DGAT2 gene is a candidate for the dissociation between fatty liver and insulin resistance in humans.
Clinical science (London, England : 1979) 2009;116(6):531-7.
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2009: Laske Christoph; Stransky Elke; Fritsche Andreas; Eschweiler Gerhard W; Leyhe Thomas
Inverse association of cortisol serum levels with T-tau, P-tau 181 and P-tau 231 peptide levels and T-tau/Abeta 1-42 ratios in CSF in patients with mild Alzheimer's disease dementia.
European archives of psychiatry and clinical neuroscience 2009;259(2):80-5.
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2009: Silbernagel G; Stefan N; Hoffmann M M; Machicao-Arano F; Machann J; Schick F; Winkelmann B R; Boehm B O; Häring H U; Fritsche A; März W
The L162V polymorphism of the peroxisome proliferator activated receptor alpha gene (PPARA) is not associated with type 2 diabetes, BMI or body fat composition.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(3):113-8.
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2009: Kantartzis Konstantinos; Staiger Harald; Machann Jürgen; Schick Fritz; Claussen Claus D; Machicao Fausto; Fritsche Andreas; Häring Hans-Ulrich; Stefan Norbert
Adiponectin oligomers and ectopic fat in liver and skeletal muscle in humans.
Obesity (Silver Spring, Md.) 2009;17(2):390-2.
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2009: Weyrich P; Albet S; Lammers R; Machicao F; Fritsche A; Stefan N; Häring H-U
Genetic variability of procolipase associates with altered insulin secretion in non-diabetic Caucasians.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(2):83-7.
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2009: Giel Katrin E; Enck Paul; Zipfel Stephan; Schrauth Markus; Bury Anna; Graf Marjo; Kümmerle Sabine; Guthoff Martina; Stefan Norbert; Häring Hans-Ulrich; Fritsche Andreas
Psychological effects of prevention: do participants of a type 2 diabetes prevention program experience increased mental distress?
Diabetes/metabolism research and reviews 2009;25(1):83-8.
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2009: Staiger H; Wöll J; Haas C; Machicao F; Schleicher E D; Fritsche A; Stefan N; Häring H-U
Selective association of plasma non-esterified fatty acid species with circulating interleukin-8 concentrations in humans.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(1):21-7.
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2009: Tschritter O; Hennige A M; Preissl H; Grichisch Y; Kirchhoff K; Kantartzis K; Machicao F; Fritsche A; Häring H-U
Insulin effects on beta and theta activity in the human brain are differentially affected by ageing.
Diabetologia 2009;52(1):169-71.
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2009: Weyrich Peter; Staiger Harald; Stancáková Alena; Schäfer Silke A; Kirchhoff Kerstin; Ullrich Susanne; Ranta Felicia; Gallwitz Baptist; Stefan Norbert; Machicao Fausto; Kuusisto Johanna; Laakso Markku; Fritsche Andreas; Häring Hans-Ulrich
Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced beta-cell function in non-diabetic subjects.
BMC medical genetics 2009;10():77.
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2008: Schwenzer Nina F; Machann Jürgen; Haap Michael M; Martirosian Petros; Schraml Christina; Liebig Gerd; Stefan Norbert; Häring Hans-Ulrich; Claussen Claus D; Fritsche Andreas; Schick Fritz
T2* relaxometry in liver, pancreas, and spleen in a healthy cohort of one hundred twenty-nine subjects-correlation with age, gender, and serum ferritin.
Investigative radiology 2008;43(12):854-60.
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2008: Rittig K; Staib K; Machann J; Böttcher M; Peter A; Schick F; Claussen C; Stefan N; Fritsche A; Häring H-U; Balletshofer B
Perivascular fatty tissue at the brachial artery is linked to insulin resistance but not to local endothelial dysfunction.
Diabetologia 2008;51(11):2093-9.
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2008: Stefan Norbert; Fritsche Andreas; Weikert Cornelia; Boeing Heiner; Joost Hans-Georg; Häring Hans-Ulrich; Schulze Matthias B
Plasma fetuin-A levels and the risk of type 2 diabetes.
Diabetes 2008;57(10):2762-7.
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2008: Stefan Norbert; Kantartzis Konstantinos; Machann Jürgen; Schick Fritz; Thamer Claus; Rittig Kilian; Balletshofer Bernd; Machicao Fausto; Fritsche Andreas; Häring Hans-Ulrich
Identification and characterization of metabolically benign obesity in humans.
Archives of internal medicine 2008;168(15):1609-16.
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2008: Fritsche A
[Long acting insulin analogues: results of clinical studies with insulin glargine]
Deutsche medizinische Wochenschrift (1946) 2008;133 Suppl 4():S101-5; discussion S124-6.
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2008: Haupt Axel; Thamer Claus; Machann Jürgen; Kirchhoff Kerstin; Stefan Norbert; Tschritter Otto; Machicao Fausto; Schick Fritz; Häring Hans-Ulrich; Fritsche Andreas
Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss.
Obesity (Silver Spring, Md.) 2008;16(8):1969-72.
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2008: Müssig Karsten; Remer Thomas; Haupt Axel; Gallwitz Baptist; Fritsche Andreas; Häring Hans-Ulrich; Maser-Gluth Christiane
11beta-hydroxysteroid dehydrogenase 2 activity is elevated in severe obesity and negatively associated with insulin sensitivity.
Obesity (Silver Spring, Md.) 2008;16(6):1256-60.
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2008: Rittig Kilian; Peter Andreas; Baltz Katrin M; Tschritter Otto; Weigert Cora; Andreozzi Francesco; Perticone Francesco; Siegel-Axel Dorothea I; Stefan Norbert; Fritsche Andreas; Salih Helmut R; Schleicher Erwin; Machicao Fausto; Sesti Giorgio; Häring Hans-Ulrich; Balletshofer Bernd M
The CCR2 promoter polymorphism T-960A, but not the serum MCP-1 level, is associated with endothelial function in prediabetic individuals.
Atherosclerosis 2008;198(2):338-46.
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2008: Staiger Harald; Machicao Fausto; Werner Roman; Guirguis Alke; Weisser Melanie; Stefan Norbert; Fritsche Andreas; Häring Hans-Ulrich
Genetic variation within the ANGPTL4 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus.
Metabolism: clinical and experimental 2008;57(5):637-43.
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2008: Schwenzer Nina F; Machann Jürgen; Martirosian Petros; Stefan Norbert; Schraml Christina; Fritsche Andreas; Claussen Claus D; Schick Fritz
Quantification of pancreatic lipomatosis and liver steatosis by MRI: comparison of in/opposed-phase and spectral-spatial excitation techniques.
Investigative radiology 2008;43(5):330-7.
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2008: Stefan N; Peter A; Cegan A; Staiger H; Machann J; Schick F; Claussen C D; Fritsche A; Häring H-U; Schleicher E
Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans.
Diabetologia 2008;51(4):648-56.
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2008: Kirchhoff K; Machicao F; Haupt A; Schäfer S A; Tschritter O; Staiger H; Stefan N; Häring H-U; Fritsche A
Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.
Diabetologia 2008;51(4):597-601.
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2008: Thamer Claus; Machann Jürgen; Stefan Norbert; Schäfer Silke A; Machicao Fausto; Staiger Harald; Laakso Markku; Böttcher Michael; Claussen Claus; Schick Fritz; Fritsche Andreas; Haring Hans-Ulrich
Variations in PPARD determine the change in body composition during lifestyle intervention: a whole-body magnetic resonance study.
The Journal of clinical endocrinology and metabolism 2008;93(4):1497-500.
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2008: Kantartzis Konstantinos; Rittig Kilian; Cegan Alexander; Machann Jürgen; Schick Fritz; Balletshofer Bernd; Fritsche Andreas; Schleicher Erwin; Häring Hans-Ulrich; Stefan Norbert
Fatty liver is independently associated with alterations in circulating HDL2 and HDL3 subfractions.
Diabetes care 2008;31(2):366-8.
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2008: Rittig K; Holder K; Stock J; Tschritter O; Peter A; Stefan N; Fritsche A; Machicao F; Häring H-U; Balletshofer B
Endothelial NO-synthase intron 4 polymorphism is associated with disturbed in vivo nitric oxide production in individuals prone to type 2 diabetes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(1):13-7.
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2008: Weyrich Peter; Machicao Fausto; Reinhardt Julia; Machann Jürgen; Schick Fritz; Tschritter Otto; Stefan Norbert; Fritsche Andreas; Häring Hans-Ulrich
SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention--the TULIP Study.
BMC medical genetics 2008;9():100.
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2008: Friedrich Björn; Weyrich Peter; Stancáková Alena; Wang Jianjung; Kuusisto Johanna; Laakso Markku; Sesti Giorgio; Succurro Elena; Smith Ulf; Hansen Torben; Pedersen Oluf; Machicao Fausto; Schäfer Silke; Lang Florian; Risler Teut; Ullrich Susanne; Stefan Norbert; Fritsche Andreas; Häring Hans-Ulrich
Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.
PloS one 2008;3(11):e3506.
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2008: Staiger Harald; Machicao Fausto; Kantartzis Konstantinos; Schäfer Silke A; Kirchhoff Kerstin; Guthoff Martina; Silbernagel Günther; Stefan Norbert; Fritsche Andreas; Häring Hans-Ulrich
Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.
PloS one 2008;3(8):e3019.
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2008: Hennige Anita M; Staiger Harald; Wicke Corinna; Machicao Fausto; Fritsche Andreas; Häring Hans-Ulrich; Stefan Norbert
Fetuin-A induces cytokine expression and suppresses adiponectin production.
PloS one 2008;3(3):e1765.
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2007: Tschritter O; Preissl H; Yokoyama Y; Machicao F; Häring H-U; Fritsche A
Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans.
Diabetologia 2007;50(12):2602-3.
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2007: Schäfer S A; Tschritter O; Machicao F; Thamer C; Stefan N; Gallwitz B; Holst J J; Dekker J M; 't Hart L M; Nijpels G; van Haeften T W; Häring H U; Fritsche A
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.
Diabetologia 2007;50(12):2443-50.
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2007: Weyrich P; Machicao F; Staiger H; Simon P; Thamer C; Machann J; Schick F; Guirguis A; Fritsche A; Stefan N; Häring H-U
Role of AMP-activated protein kinase gamma 3 genetic variability in glucose and lipid metabolism in non-diabetic whites.
Diabetologia 2007;50(10):2097-106.
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2007: Stefan Norbert; Hennige Anita M; Staiger Harald; Schleicher Erwin; Fritsche Andreas; Häring Hans-Ulrich
Circulating retinol-binding protein-4, insulin sensitivity, insulin secretion, and insulin disposition index in obese and nonobese subjects: response to Broch et al.
Diabetes care 2007;30(8):e91; author reply e92.
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2007: Staiger H; Machicao F; Machann J; Schick F; Kuulasmaa T; Laakso M; Fritsche A; Stefan N; Häring H-U
Genetic variation within the APPL locus is not associated with metabolic or inflammatory traits in a healthy White population.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(8):817-22.
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2007: Schäfer S; Kantartzis K; Machann J; Venter C; Niess A; Schick F; Machicao F; Häring H-U; Fritsche A; Stefan N
Lifestyle intervention in individuals with normal versus impaired glucose tolerance.
European journal of clinical investigation 2007;37(7):535-43.
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2007: Rittig K; Thamer C; Machicao F; Rietig R; Stefan N; Fritsche A; Haring H-U; Balletshofer B
The Pro12Ala polymorphism in PPARG2 increases the effectiveness of primary prevention of cardiovascular disease by a lifestyle intervention.
Diabetologia 2007;50(6):1345-7.
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2007: Stefan Norbert; Hennige Anita M; Staiger Harald; Machann Jürgen; Schick Fritz; Schleicher Erwin; Fritsche Andreas; Häring Hans-Ulrich
High circulating retinol-binding protein 4 is associated with elevated liver fat but not with total, subcutaneous, visceral, or intramyocellular fat in humans.
Diabetes care 2007;30(5):1173-8.
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2007: Thamer Claus; Machann Juergen; Stefan Norbert; Haap Michael; Schäfer Silke; Brenner Sonja; Kantartzis Konstantin; Claussen Claus; Schick Fritz; Haring Hans; Fritsche Andreas
High visceral fat mass and high liver fat are associated with resistance to lifestyle intervention.
Obesity (Silver Spring, Md.) 2007;15(2):531-8.
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2007: Weyrich Peter; Stefan Norbert; Häring Hans-Ulrich; Laakso Markku; Fritsche Andreas
Effect of genotype on success of lifestyle intervention in subjects at risk for type 2 diabetes.
Journal of molecular medicine (Berlin, Germany) 2007;85(2):107-17.
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2007: Kantartzis Konstantinos; Fritsche Andreas; Machicao Fausto; Stumvoll Michael; Machann Jürgen; Schick Fritz; Häring Hans-Ulrich; Stefan Norbert
Upstream transcription factor 1 gene polymorphisms are associated with high antilipolytic insulin sensitivity and show gene-gene interactions.
Journal of molecular medicine (Berlin, Germany) 2007;85(1):55-61.
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2007: Tschritter Otto; Hennige Anita M; Preissl Hubert; Porubska Katarina; Schäfer Silke A; Lutzenberger Werner; Machicao Fausto; Birbaumer Niels; Fritsche Andreas; Häring Hans-Ulrich
Cerebrocortical beta activity in overweight humans responds to insulin detemir.
PloS one 2007;2(11):e1196.
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2007: Staiger Harald; Machicao Fausto; Stefan Norbert; Tschritter Otto; Thamer Claus; Kantartzis Konstantinos; Schäfer Silke A; Kirchhoff Kerstin; Fritsche Andreas; Häring Hans-Ulrich
Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.
PloS one 2007;2(9):e832.
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2006: Kantartzis Konstantinos; Rittig Killian; Balletshofer Bernd; Machann Jürgen; Schick Fritz; Porubska Katarina; Fritsche Andreas; Häring Hans-Ulrich; Stefan Norbert
The relationships of plasma adiponectin with a favorable lipid profile, decreased inflammation, and less ectopic fat accumulation depend on adiposity.
Clinical chemistry 2006;52(10):1934-42.
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2006: Porubská Katarína; Veit Ralf; Preissl Hubert; Fritsche Andreas; Birbaumer Niels
Subjective feeling of appetite modulates brain activity: an fMRI study.
NeuroImage 2006;32(3):1273-80.
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2006: Tschritter Otto; Preissl Hubert; Hennige Anita M; Stumvoll Michael; Porubska Katarina; Frost Rebekka; Marx Hannah; Klösel Benjamin; Lutzenberger Werner; Birbaumer Niels; Häring Hans-Ulrich; Fritsche Andreas
The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: a magnetoencephalographic study.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(32):12103-8.
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2006: Schäfer S A; Müssig K; Stefan N; Häring H-U; Fritsche A; Balletshofer B M
Plasma homocysteine concentrations in young individuals at increased risk of type 2 diabetes are associated with subtle differences in glomerular filtration rate but not with insulin resistance.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2006;114(6):306-9.
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2006: Hennige A M; Sartorius T; Tschritter O; Preissl H; Fritsche A; Ruth P; Häring H-U
Tissue selectivity of insulin detemir action in vivo.
Diabetologia 2006;49(6):1274-82.
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2006: Haap M; Heller E; Thamer C; Tschritter O; Stefan N; Fritsche A
Association of serum phosphate levels with glucose tolerance, insulin sensitivity and insulin secretion in non-diabetic subjects.
European journal of clinical nutrition 2006;60(6):734-9.
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2006: Stefan Norbert; Hennige Anita M; Staiger Harald; Machann Jürgen; Schick Fritz; Kröber Stefan M; Machicao Fausto; Fritsche Andreas; Häring Hans-Ulrich
Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans.
Diabetes care 2006;29(4):853-7.
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2006: Machann Jürgen; Thamer Claus; Schnoedt Birgit; Stefan Norbert; Haring Hans-Ulrich; Claussen Claus D; Fritsche Andreas; Schick Fritz
Hepatic lipid accumulation in healthy subjects: a comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;55(4):913-7.
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2006: Thamer C; Haap M; Heller E; Joel L; Braun S; Tschritter O; Haring H; Fritsche A
Beta cell function, insulin resistance and plasma adiponectin concentrations are predictors for the change of postprandial glucose in non-diabetic subjects at risk for type 2 diabetes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(3):178-82.
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2006: Kantartzis Konstantinos; Fritsche Andreas; Machicao Fausto; Häring Hans-Ulrich; Stefan Norbert
The -8503 G/A polymorphism of the adiponectin receptor 1 gene is associated with insulin sensitivity dependent on adiposity.
Diabetes care 2006;29(2):464.
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2006: Tschritter Otto; Machicao Fausto; Stefan Norbert; Schäfer Silke; Weigert Cora; Staiger Harald; Spieth Christian; Häring Hans-Ulrich; Fritsche Andreas
A new variant in the human Kv1.3 gene is associated with low insulin sensitivity and impaired glucose tolerance.
The Journal of clinical endocrinology and metabolism 2006;91(2):654-8.
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2005: Staiger K; Stefan N; Staiger H; Brendel M D; Brandhorst D; Bretzel R G; Machicao F; Kellerer M; Stumvoll M; Fritsche A; Häring H-U
Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis.
The Journal of clinical endocrinology and metabolism 2005;90(12):6707-13.
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2005: Stefan N; Machicao F; Staiger H; Machann J; Schick F; Tschritter O; Spieth C; Weigert C; Fritsche A; Stumvoll M; Häring H U
Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.
Diabetologia 2005;48(11):2282-91.
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2005: Kantartzis Konstantinos; Fritsche Andreas; Tschritter Otto; Thamer Claus; Haap Michael; Schäfer Silke; Stumvoll Michael; Häring Hans-Ulrich; Stefan Norbert
The association between plasma adiponectin and insulin sensitivity in humans depends on obesity.
Obesity research 2005;13(10):1683-91.
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2005: Machann J; Thamer C; Schnoedt B; Stefan N; Stumvoll M; Haring H-U; Claussen C D; Fritsche A; Schick F
Age and gender related effects on adipose tissue compartments of subjects with increased risk for type 2 diabetes: a whole body MRI/MRS study.
Magma (New York, N.Y.) 2005;18(3):128-37.
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2005: Stefan Norbert; Schäfer Silke; Machicao Fausto; Machann Jürgen; Schick Fritz; Claussen Claus D; Stumvoll Michael; Häring Hans-Ulrich; Fritsche Andreas
Liver fat and insulin resistance are independently associated with the -514C>T polymorphism of the hepatic lipase gene.
The Journal of clinical endocrinology and metabolism 2005;90(7):4238-43.
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2005: Haap M; Machicao F; Stefan N; Thamer C; Tschritter O; Schnuck F; Wallwiener D; Stumvoll M; Häring H-U; Fritsche A
Genetic determinants of insulin action in polycystic ovary syndrome.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2005;113(5):275-81.
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2005: Thamer C; Tschritter O; Haap M; Shirkavand F; Machann J; Fritsche A; Schick F; Häring H; Stumvoll M
Elevated serum GGT concentrations predict reduced insulin sensitivity and increased intrahepatic lipids.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37(4):246-51.
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2005: Machann Jürgen; Thamer Claus; Schnoedt Birgit; Haap Michael; Haring Hans-Ulrich; Claussen Claus D; Stumvoll Michael; Fritsche Andreas; Schick Fritz
Standardized assessment of whole body adipose tissue topography by MRI.
Journal of magnetic resonance imaging : JMRI 2005;21(4):455-62.
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2005: Weyrich P; Lammers R; Fritsche A; Machicao F; Häring H-U; Stefan N
A novel functional polymorphism (-336A/G) in the promoter of the partitioning-defective protein-6alpha gene is associated with increased glucose tolerance and lower concentrations of serum non-esterified fatty acids.
Diabetologia 2005;48(4):669-74.
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2005: Weigert Cora; Thamer Claus; Brodbeck Katrin; Guirguis Alke; Machicao Fausto; Machann Jürgen; Schick Fritz; Stumvoll Michael; Fritsche Andreas; Häring Hans U; Schleicher Erwin D
The -913 G/A glutamine:fructose-6-phosphate aminotransferase gene polymorphism is associated with measures of obesity and intramyocellular lipid content in nondiabetic subjects.
The Journal of clinical endocrinology and metabolism 2005;90(3):1639-43.
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2005: Stefan Norbert; Machann Jürgen; Schick Fritz; Claussen Claus D; Thamer Claus; Fritsche Andreas; Häring Hans-Ulrich
New imaging techniques of fat, muscle and liver within the context of determining insulin sensitivity.
Hormone research 2005;64 Suppl 3():38-44.
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2004: Thamer Claus; Machann Jürgen; Haap Michael; Stefan Norbert; Heller Emanuela; Schnödt Birgit; Stumvoll Michael; Claussen Claus; Fritsche Andreas; Schick Fritz; Häring Hans
Intrahepatic lipids are predicted by visceral adipose tissue mass in healthy subjects.
Diabetes care 2004;27(11):2726-9.
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2004: Staiger Harald; Kaltenbach Simone; Staiger Katrin; Stefan Norbert; Fritsche Andreas; Guirguis Alke; Péterfi Claudia; Weisser Melanie; Machicao Fausto; Stumvoll Michael; Häring Hans-Ulrich
Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism.
Diabetes 2004;53(9):2195-201.
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2004: Fritsche A; Häring H
At last, a weight neutral insulin?
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2004;28 Suppl 2():S41-6.
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2004: Thamer C; Haap M; Bachmann O; Zur Nieden T; Tschritter O; Stefan N; Fritsche A; Jacob S; Stumvoll M; Häring H
Serum adiponectin levels predict the effect of short-term dietary interventions on insulin sensitivity in humans.
Diabetologia 2004;47(7):1303-5.
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2004: Machicao F; Staiger H; Fritsche A; Guirguis A; Weisser M; Stumvoll M; Häring H-U
Association of the -514C-->T polymorphism in the hepatic lipase gene (LIPC) promoter with elevated fasting insulin concentrations, but not insulin resistance, in non-diabetic Germans.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(5):303-6.
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2004: Stumvoll M; Fritsche A; t'Hart L M; Machann J; Thamer C; Tschritter O; Van Haeften T W; Jacob S; Dekker J M; Maassen J A; Machicao F; Schick F; Heine R J; Häring H
The Gly482Ser variant in the peroxisome proliferator-activated receptor gamma coactivator-1 is not associated with diabetes-related traits in non-diabetic German and Dutch populations.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2004;112(5):253-7.
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2004: Stefan Norbert; Stumvoll Michael; Machicao Fausto; Koch Matthias; Häring Hans U; Fritsche Andreas
C825T polymorphism of the G protein beta3 subunit is associated with obesity but not with insulin sensitivity.
Obesity research 2004;12(4):679-83.
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2004: Thamer C; Machann J; Haap M; Bachmann O; Wietek B; Dahl D; Tschritter O; Fritsche A; Jacob S; Schick F; Stumvoll M; Häring H
[Reduced insulin effect in subclinical fatty liver]
Deutsche medizinische Wochenschrift (1946) 2004;129(16):872-5.
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2004: Fritsche A; Häring H; Stumvoll M
[White blood cell count as a predictor of glucose tolerance and insulin sensitivity. The role of inflammation in the pathogenesis of type 2 diabetes mellitus]
Deutsche medizinische Wochenschrift (1946) 2004;129(6):244-8.
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2003: Stumvoll M; Häring H; Fritsche A
For debate: Starling's curve of the pancreas--overuse of a concept?
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2003;35(7):391-5.
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2003: Thamer Claus; Stumvoll Michael; Niess Andreas; Tschritter Otto; Haap Michael; Becker Regine; Shirkavand Fatemeh; Bachmann Oliver; Rett Kristian; Volk Annette; Häring Hans; Fritsche Andreas
Reduced skeletal muscle oxygen uptake and reduced beta-cell function: two early abnormalities in normal glucose-tolerant offspring of patients with type 2 diabetes.
Diabetes care 2003;26(7):2126-32.
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2003: Fritsche Andreas; Schweitzer Matthias Axel; Häring Hans-Ulrich;
Glimepiride combined with morning insulin glargine, bedtime neutral protamine hagedorn insulin, or bedtime insulin glargine in patients with type 2 diabetes. A randomized, controlled trial.
Annals of internal medicine 2003;138(12):952-9.
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2003: Tschritter Otto; Fritsche Andreas; Stefan Norbert; Haap Michael; Thamer Claus; Bachmann Oliver; Dahl Dominik; Maerker Elke; Teigeler Anna; Machicao Fausto; Häring Hans; Stumvoll Michael
Increased insulin clearance in peroxisome proliferator-activated receptor gamma2 Pro12Ala.
Metabolism: clinical and experimental 2003;52(6):778-83.
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2003: Fritsche Andreas; Stumvoll Michael; Häring Hans-Ulrich
[Insulin secretion and aging. Implications for insulin therapy in the geriatric patient with diabetes mellitus]
Medizinische Klinik (Munich, Germany : 1983) 2003;98(5):287-91.
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2003: Thamer Claus; Machann Jürgen; Bachmann Oliver; Haap Michael; Dahl Dominik; Wietek Beate; Tschritter Otto; Niess Andreas; Brechtel Klaus; Fritsche Andreas; Claussen Claus; Jacob Stephan; Schick Fritz; Häring Hans-Ulrich; Stumvoll Michael
Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity.
The Journal of clinical endocrinology and metabolism 2003;88(4):1785-91.
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2003: Tschritter Otto; Fritsche Andreas; Shirkavand Fatemeh; Machicao Fausto; Häring Hans; Stumvoll Michael
Assessing the shape of the glucose curve during an oral glucose tolerance test.
Diabetes care 2003;26(4):1026-33.
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2003: Staiger Harald; Tschritter Otto; Machann Jürgen; Thamer Claus; Fritsche Andreas; Maerker Elke; Schick Fritz; Häring Hans-Ulrich; Stumvoll Michael
Relationship of serum adiponectin and leptin concentrations with body fat distribution in humans.
Obesity research 2003;11(3):368-72.
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2003: Tschritter Otto; Fritsche Andreas; Thamer Claus; Haap Michael; Shirkavand Fatemeh; Rahe Stefanie; Staiger Harald; Maerker Elke; Häring Hans; Stumvoll Michael
Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism.
Diabetes 2003;52(2):239-43.
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2002: Thamer C; Machann J; Tschritter O; Haap M; Wietek B; Dahl D; Bachmann O; Fritsche A; Jacob S; Stumvoll M; Schick F; Häring H-U
Relationship between serum adiponectin concentration and intramyocellular lipid stores in humans.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(11-12):646-9.
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2002: Fritsche A; Tschritter O; Häring H; Gerich J; Stumvoll M
The role of beta-adrenergic sensitivity in the pathogenesis of hypoglycaemia unawareness.
Diabetes, nutrition & metabolism 2002;15(5):357-61; discussion 361-2.
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2002: Tschritter Otto; Stumvoll Michael; Machicao Fausto; Holzwarth Martin; Weisser Melanie; Maerker Elke; Teigeler Anna; Häring Hans; Fritsche Andreas
The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia.
Diabetes 2002;51(9):2854-60.
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2002: Fritsche Andreas; Madaus Alexander; Stefan Norbert; Tschritter Otto; Maerker Elke; Teigeler Anna; Häring Hans; Stumvoll Michael
Relationships among age, proinsulin conversion, and beta-cell function in nondiabetic humans.
Diabetes 2002;51 Suppl 1():S234-9.
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2002: Stumvoll Michael; Fritsche Andreas; Häring Hans-Ulrich
Clinical characterization of insulin secretion as the basis for genetic analyses.
Diabetes 2002;51 Suppl 1():S122-9.
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2002: Stumvoll Michael; Stefan Norbert; Fritsche Andreas; Madaus Alexander; Tschritter Otto; Koch Matthias; Machicao Fausto; Häring Hans
Interaction effect between common polymorphisms in PPARgamma2 (Pro12Ala) and insulin receptor substrate 1 (Gly972Arg) on insulin sensitivity.
Journal of molecular medicine (Berlin, Germany) 2002;80(1):33-8.
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2002: Hennige Anita M; Fritsche Andreas; Strack Volker; Weigert Cora; Mischak Harald; Borboni Patricia; Renn Walter; Häring Hans-Ulrich; Kellerer Monika
PKC zeta enhances insulin-like growth factor 1-dependent mitogenic activity in the rat clonal beta cell line RIN 1046-38.
Biochemical and biophysical research communications 2002;290(1):85-90.
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2002: Stumvoll Michael; Tschritter Otto; Fritsche Andreas; Staiger Harald; Renn Walter; Weisser Melanie; Machicao Fausto; Häring Hans
Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes.
Diabetes 2002;51(1):37-41.
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2001: Fritsche A; Madaus A; Renn W; Tschritter O; Teigeler A; Weisser M; Maerker E; Machicao F; Häring H; Stumvoll M
The prevalent Gly1057Asp polymorphism in the insulin receptor substrate-2 gene is not associated with impaired insulin secretion.
The Journal of clinical endocrinology and metabolism 2001;86(10):4822-5.
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2001: Kellerer M; Lammers R; Fritsche A; Strack V; Machicao F; Borboni P; Ullrich A; Häring H U
Insulin inhibits leptin receptor signalling in HEK293 cells at the level of janus kinase-2: a potential mechanism for hyperinsulinaemia-associated leptin resistance.
Diabetologia 2001;44(9):1125-32.
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2001: Stumvoll M; Fritsche A; Madaus A; Stefan N; Weisser M; Machicao F; Häring H
Functional significance of the UCSNP-43 polymorphism in the CAPN10 gene for proinsulin processing and insulin secretion in nondiabetic Germans.
Diabetes 2001;50(9):2161-3.
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2001: Stefan N; Wahl H G; Fritsche A; Häring H; Stumvoll M
Effect of the pattern of elevated free fatty acids on insulin sensitivity and insulin secretion in healthy humans.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2001;33(7):432-8.
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2001: Fritsche A; Madaus A; Tschritter O; Ozeker M; Wulle E L; Machicao F; Häring H; Stumvoll M
[Polymorphism of pro12Ala in peroxisome proliferator activated receptor gamma 2 (PPAgamma2): beta cell function and insulin sensitivity]
Deutsche medizinische Wochenschrift (1946) 2001;126(20):580-4.
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2001: Stumvoll M; Fritsche A; Häring H
The OGTT as test for beta cell function?
European journal of clinical investigation 2001;31(5):380-1.
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2001: Stefan N; Fritsche A; Häring H; Stumvoll M
Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene.
Diabetes 2001;50(5):1143-8.
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2001: Stumvoll M; Fritsche A; Volk A; Stefan N; Madaus A; Maerker E; Teigeler A; Koch M; Machicao F; Häring H
The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans.
Diabetes 2001;50(4):882-5.
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2001: Stumvoll M; Fritsche A; Stefan N; Hardt E; Häring H
Evidence against a rate-limiting role of proinsulin processing for maximal insulin secretion in subjects with impaired glucose tolerance and beta-cell dysfunction.
The Journal of clinical endocrinology and metabolism 2001;86(3):1235-9.
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2001: Stefan N; Fritsche A; Häring H; Stumvoll M
Acute stimulation of leptin concentrations in humans during hyperglycemic hyperinsulinemia. Influence of free fatty acids and fasting.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(1):138-42.
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2000: Stefan N; Fritsche A; Madaus A; Häring H; Stumvoll M
Stimulatory effect of increased non-esterified fatty acid concentrations on proinsulin processing in healthy humans.
Diabetologia 2000;43(11):1368-73.
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2000: Fritsche A; Stefan N; Hardt E; Häring H; Stumvoll M
Characterisation of beta-cell dysfunction of impaired glucose tolerance: evidence for impairment of incretin-induced insulin secretion.
Diabetologia 2000;43(7):852-8.
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2000: Stumvoll M; Fritsche A; Stefan N; Häring H
A 60 minute hyperglycemic clamp is sufficient to assess both phases of insulin secretion.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2000;32(6):230-2.
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2000: Fritsche A; Stefan N; Hardt E; Schützenauer S; Häring H; Stumvoll M
A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility.
European journal of clinical investigation 2000;30(5):411-8.
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2000: Fritsche A; Schmülling R M; Häring H U; Stumvoll M
Intensive insulin therapy combined with metformin in obese type 2 diabetic patients.
Acta diabetologica 2000;37(1):13-8.
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2000: Stumvoll M; Fritsche A; Tschritter O; Lehmann R; Wahl H G; Renn W; Häring H
Leptin levels in humans are acutely suppressed by isoproterenol despite acipimox-induced inhibition of lipolysis, but not by free fatty acids.
Metabolism: clinical and experimental 2000;49(3):335-9.
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2000: Fritsche A; Stumvoll M; Häring H U; Gerich J E
Reversal of hypoglycemia unawareness in a long-term type 1 diabetic patient by improvement of beta-adrenergic sensitivity after prevention of hypoglycemia.
The Journal of clinical endocrinology and metabolism 2000;85(2):523-5.
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1999: Fritsche A; Stumvoll M; Goebbel S; Reinauer K M; Schmülling R M; Häring H U
Long term effect of a structured inpatient diabetes teaching and treatment programme in type 2 diabetic patients: influence of mode of follow-up.
Diabetes research and clinical practice 1999;46(2):135-41.
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1998: Fritsche A; Stumvoll M; Grüb M; Sieslack S; Renn W; Schmülling R M; Häring H U; Gerich J E
Effect of hypoglycemia on beta-adrenergic sensitivity in normal and type 1 diabetic subjects.
Diabetes care 1998;21(9):1505-10.
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1998: Fritsche A; Stumvoll M; Renn W; Schmülling R M
Diabetes teaching program improves glycemic control and preserves perception of hypoglycemia.
Diabetes research and clinical practice 1998;40(2):129-35.
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1998: Fritsche A; Wahl H G; Metzinger E; Renn W; Kellerer M; Häring H; Stumvoll M
Evidence for inhibition of leptin secretion by catecholamines in man.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1998;106(5):415-8.
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1997: Stumvoll M; Fritsche A
Necrotizing fasciitis caused by unencapsulated Haemophilus influenzae.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997;25(2):327.
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1996: Stumvoll M; Fritsche A; Wehrmann M; Dammann F; Becker H D; Eggstein M
A functioning adrenocortical hemangioma.
The Journal of urology 1996;155(2):638.
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1992: Iser G; Fritsche A; Eggstein M
[MODY diabetes]
Deutsche medizinische Wochenschrift (1946) 1992;117(51-52):1985-6.
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