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Hans-Joachim Fritz

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Lars Schomacher; Sabine Smolorz; Elena Ciirdaeva; Svetlana Ber; Wilfried Kramer; Hans-Joachim Fritz
Helix-hairpin-helix protein MJ1434 from Methanocaldococcus jannaschii and EndoIV homologue TTC0482 from Thermus thermophilus HB27 do not process DNA uracil residues.
Lars Schomacher; K Anke Schürer; Elena Ciirdaeva; Paul McDermott; James P J Chong; Wilfried Kramer; Hans-Joachim Fritz
Archaeal DNA uracil repair via direct strand incision: A minimal system reconstituted from purified components.
Lars Schomacher; James P J Chong; Paul McDermott; Wilfried Kramer; Hans-Joachim Fritz
DNA uracil repair initiated by the archaeal ExoIII homologue Mth212 via direct strand incision.

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All Publications

2010: Lars Schomacher; Sabine Smolorz; Elena Ciirdaeva; Svetlana Ber; Wilfried Kramer; Hans-Joachim Fritz
Helix-hairpin-helix protein MJ1434 from Methanocaldococcus jannaschii and EndoIV homologue TTC0482 from Thermus thermophilus HB27 do not process DNA uracil residues.
Nucleic acids research 2010;38(15):5119-29.
2010: Lars Schomacher; K Anke Schürer; Elena Ciirdaeva; Paul McDermott; James P J Chong; Wilfried Kramer; Hans-Joachim Fritz
Archaeal DNA uracil repair via direct strand incision: A minimal system reconstituted from purified components.
DNA repair 2010;9(4):438-47.
2009: Lars Schomacher; James P J Chong; Paul McDermott; Wilfried Kramer; Hans-Joachim Fritz
DNA uracil repair initiated by the archaeal ExoIII homologue Mth212 via direct strand incision.
Nucleic acids research 2009;37(7):2283-93.
2006: Jens Georg; Lars Schomacher; James P J Chong; Alan I Majerník; Monika Raabe; Henning Urlaub; Sabine Müller; Elena Ciirdaeva; Wilfried Kramer; Hans-Joachim Fritz
The Methanothermobacter thermautotrophicus ExoIII homologue Mth212 is a DNA uridine endonuclease.
Nucleic acids research 2006;34(18):5325-36.
2004: Anke Henne; Holger Bruggemann; Carsten Raasch; Arnim Wiezer; Thomas Hartsch; Heiko Liesegang; Andre Johann; Tanja Lienard; Olivia Gohl; Rosa Martinez-Arias; Carsten Jacobi; Vytaute Starkuviene; Silke Schlenczeck; Silke Dencker; Robert Huber; Hans-Peter Klenk; Wilfried Kramer; Rainer Merkl; Gerhard Gottschalk; Hans-Joachim Fritz
The genome sequence of the extreme thermophile Thermus thermophilus.
Nature biotechnology 2004;22(5):547-53.
2003: Martin Laging; Eric Lindner; Hans-Joachim Fritz; Wilfried Kramer
Repair of hydrolytic DNA deamination damage in thermophilic bacteria: cloning and characterization of a Vsr endonuclease homolog from Bacillus stearothermophilus.
Nucleic acids research 2003;31(7):1913-20.
2002: Karen D Larbig; Andreas Christmann; Andre Johann; Jens Klockgether; Thomas Hartsch; Rainer Merkl; Lutz Wiehlmann; Hans-Joachim Fritz; Burkhard Tümmler
Gene islands integrated into tRNA(Gly) genes confer genome diversity on a Pseudomonas aeruginosa clone.
Journal of bacteriology 2002;184(23):6665-80.
2002: Uwe Deppenmeier; Andre Johann; Thomas Hartsch; Rainer Merkl; Ruth A Schmitz; Rosa Martinez-Arias; Anke Henne; Arnim Wiezer; Sebastian Bäumer; Carsten Jacobi; Holger Bruggemann; Tanja Lienard; Andreas Christmann; Mechthild Bömeke; Silke Steckel; Anamitra Bhattacharyya; Athanasios Lykidis; Ross Overbeek; Hans-Peter Klenk; Robert P Gunsalus; Hans-Joachim Fritz; Gerhard Gottschalk
The genome of Methanosarcina mazei: evidence for lateral gene transfer between bacteria and archaea.
Journal of molecular microbiology and biotechnology 2002;4(4):453-61.
2002: Vytaute Starkuviene; Hans-Joachim Fritz
A novel type of uracil-DNA glycosylase mediating repair of hydrolytic DNA damage in the extremely thermophilic eubacterium Thermus thermophilus.
Nucleic acids research 2002;30(10):2097-102.
2002: Yvonne N Fondufe-Mittendorf; Christine Härer; Wilfried Kramer; Hans-Joachim Fritz
Two amino acid replacements change the substrate preference of DNA mismatch glycosylase Mig.MthI from T/G to A/G.
Nucleic acids research 2002;30(2):614-21.
1999: Isabel Usón; Ehmke Pohl; Thomas R Schneider; Z Dauter; A Schmidt; Hans-Joachim Fritz; George M Sheldrick
1.7 A structure of the stabilized REIv mutant T39K. Application of local NCS restraints.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 6):1158-67.
1998: K Drotschmann; A Aronshtam; Hans-Joachim Fritz; M G Marinus
The Escherichia coli MutL protein stimulates binding of Vsr and MutS to heteroduplex DNA.
Nucleic acids research 1998;26(4):948-53.
1997: Isabel Usón; M T Bes; George M Sheldrick; Thomas R Schneider; Thomas Hartsch; Hans-Joachim Fritz
X-ray crystallography reveals stringent conservation of protein fold after removal of the only disulfide bridge from a stabilized immunoglobulin variable domain.
Folding & design 1997;2(6):357-61.
1996: Dieter Langosch; B Brosig; Harald Kolmar; Hans-Joachim Fritz
Dimerisation of the glycophorin A transmembrane segment in membranes probed with the ToxR transcription activator.
Journal of molecular biology 1996;263(4):525-30.
1996: Rainer Merkl; Hans-Joachim Fritz
Statistical evidence for a biochemical pathway of natural, sequence-targeted G/C to C/G transversion mutagenesis in Haemophilus influenzae Rd.
Nucleic acids research 1996;24(21):4146-51.
1996: J P Horst; Hans-Joachim Fritz
Counteracting the mutagenic effect of hydrolytic deamination of DNA 5-methylcytosine residues at high temperature: DNA mismatch N-glycosylase Mig.Mth of the thermophilic archaeon Methanobacterium thermoautotrophicum THF.
The EMBO journal 1996;15(19):5459-69.
1996: C Frisch; Harald Kolmar; A Schmidt; Gerd Kleemann; A Reinhardt; E Pohl; Isabel Usón; Thomas R Schneider; Hans-Joachim Fritz
Contribution of the intramolecular disulfide bridge to the folding stability of REIv, the variable domain of a human immunoglobulin kappa light chain.
Folding & design 1996;1(6):431-40.
1995: Harald Kolmar; C Frisch; K Götze; Hans-Joachim Fritz
Immunoglobulin mutant library genetically screened for folding stability exploiting bacterial signal transduction.
Journal of molecular biology 1995;251(4):471-6.
1995: Harald Kolmar; F Hennecke; K Götze; B Janzer; B Vogt; F Mayer; Hans-Joachim Fritz
Membrane insertion of the bacterial signal transduction protein ToxR and requirements of transcription activation studied by modular replacement of different protein substructures.
The EMBO journal 1995;14(16):3895-904.
1995: W Gläsner; Rainer Merkl; V Schellenberger; Hans-Joachim Fritz
Substrate preferences of Vsr DNA mismatch endonuclease and their consequences for the evolution of the Escherichia coli K-12 genome.
Journal of molecular biology 1995;245(1):1-7.
1994: M Teufel; M Pompejus; B Humbel; K Friedrich; Hans-Joachim Fritz
Properties of bacteriorhodopsin derivatives constructed by insertion of an exogenous epitope into extra-membrane loops.
The EMBO journal 1994;13(23):5794.
1994: O K Hansen; M Pompejus; Hans-Joachim Fritz
Two-chain bacteriorhodopsin synthesized by Schizosaccharomyces pombe.
Biological chemistry Hoppe-Seyler 1994;375(10):715-9.
1994: C Frisch; Harald Kolmar; Hans-Joachim Fritz
A soluble immunoglobulin variable domain without a disulfide bridge: construction, accumulation in the cytoplasm of E. coli, purification and physicochemical characterization.
Biological chemistry Hoppe-Seyler 1994;375(5):353-6.
1994: J Pschorr; B Bieseler; Hans-Joachim Fritz
Production of the immunoglobulin variable domain REIv via a fusion protein synthesized and secreted by Staphylococcus carnosus.
Biological chemistry Hoppe-Seyler 1994;375(4):271-80.
1994: Harald Kolmar; C Frisch; Gerd Kleemann; K Götze; F J Stevens; Hans-Joachim Fritz
Dimerization of Bence Jones proteins: linking the rate of transcription from an Escherichia coli promoter to the association constant of REIV.
Biological chemistry Hoppe-Seyler 1994;375(1):61-70.
1993: M Teufel; M Pompejus; B Humbel; K Friedrich; Hans-Joachim Fritz
Properties of bacteriorhodopsin derivatives constructed by insertion of an exogenous epitope into extra-membrane loops.
The EMBO journal 1993;12(9):3399-408.
1993: V Schellenberger; M Pompejus; Hans-Joachim Fritz
Peptide production by a combination of gene expression, chemical synthesis, and protease-catalyzed conversion.
International journal of peptide and protein research 1993;41(4):326-32.
1993: Theodor Hanck; S Schmidt; Hans-Joachim Fritz
Sequence-specific and mechanism-based crosslinking of Dcm DNA cytosine-C5 methyltransferase of E. coli K-12 to synthetic oligonucleotides containing 5-fluoro-2'-deoxycytidine.
Nucleic acids research 1993;21(2):303-9.
1993: M Pompejus; K Friedrich; M Teufel; Hans-Joachim Fritz
High-yield production of bacteriorhodopsin via expression of a synthetic gene in Escherichia coli.
European journal of biochemistry / FEBS 1993;211(1-2):27-35.
1992: W Gläsner; Rainer Merkl; S Schmidt; D Cech; Hans-Joachim Fritz
Fast quantitative assay of sequence-specific endonuclease activity based on DNA sequencer technology.
Biological chemistry Hoppe-Seyler 1992;373(12):1223-5.
1992: Harald Kolmar; E Ferrando; F Hennecke; J Wippler; Hans-Joachim Fritz
General mutagenesis/gene expression procedure for the construction of variant immunoglobulin domains in Escherichia coli. Production of the Bence-Jones protein REIv via fusion to beta-lactamase.
Journal of molecular biology 1992;228(2):359-65.
1992: S Schmidt; C D Pein; Hans-Joachim Fritz; D Cech
Chemical synthesis of 2'-deoxyoligonucleotides containing 5-fluoro-2'-deoxycytidine.
Nucleic acids research 1992;20(10):2421-6.
1992: Rainer Merkl; M Kröger; P Rice; Hans-Joachim Fritz
Statistical evaluation and biological interpretation of non-random abundance in the E. coli K-12 genome of tetra- and pentanucleotide sequences related to VSP DNA mismatch repair.
Nucleic acids research 1992;20(7):1657-62.
1991: F Hennecke; Harald Kolmar; K Bründl; Hans-Joachim Fritz
The vsr gene product of E. coli K-12 is a strand- and sequence-specific DNA mismatch endonuclease.
Nature 1991;353(6346):776-8.
1989: K Friedrich; Harald Kolmar; Hans-Joachim Fritz
Phasduction--a simplified protocol for oligonucleotide-directed mutagenesis by the gapped duplex DNA method.
Nucleic acids research 1989;17(14):5862.
1989: Theodor Hanck; N Gerwin; Hans-Joachim Fritz
Nucleotide sequence of the dcm locus of Escherichia coli K12.
Nucleic acids research 1989;17(14):5844.
1988: Hans-Joachim Fritz; J Hohlmaier; W Kramer; A Ohmayer; J Wippler
Oligonucleotide-directed construction of mutations: a gapped duplex DNA procedure without enzymatic reactions in vitro.
Nucleic acids research 1988;16(14B):6987-99.
1988: W Kramer; A Ohmayer; Hans-Joachim Fritz
Improved enzymatic in vitro reactions in the gapped duplex DNA approach to oligonucleotide-directed construction of mutations.
Nucleic acids research 1988;16(14B):7207.