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Jean-Charles Fruchart

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Arteriosclerosis

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Gene Expression Regulation

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Co-Publications
Name
126
Staels, Bart
53
Clavey, Véronique
37
Fievet, Catherine
37
Castro, Graciela
31
Duriez, Patrick
24
Duverger, Nicolas
24
Tailleux, Anne
21
Fruchart-Najib, Jamila
19
Fiévet, Catherine
18
Lestavel, Sophie
18
Martin-Nizard, Françoise
17
Chinetti, Giulia
16
Furman, Christophe
15
Gervois, Philippe
15
Auwerx, Johan

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Publications

TOP 3
Alberti K G M M; Eckel Robert H; Grundy Scott M; Zimmet Paul Z; Cleeman James I; Donato Karen A; Fruchart Jean-Charles; James W Philip T; Loria Catherine M; Smith Sidney C;
Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity.
Fruchart Jean-Charles
Peroxisome proliferator-activated receptor-alpha (PPARalpha): at the crossroads of obesity, diabetes and cardiovascular disease.
Brunham Liam R; Singaraja Roshni R; Duong MyNgan; Timmins Jenelle M; Fievet Catherine; Bissada Nagat; Kang Martin H; Samra Amrit; Fruchart Jean-Charles; McManus Bruce; Staels Bart; Parks John S; Hayden Michael R
Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.

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All Publications

2009: Alberti K G M M; Eckel Robert H; Grundy Scott M; Zimmet Paul Z; Cleeman James I; Donato Karen A; Fruchart Jean-Charles; James W Philip T; Loria Catherine M; Smith Sidney C;
Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity.
Circulation 2009;120(16):1640-5.
2009: Fruchart Jean-Charles
Peroxisome proliferator-activated receptor-alpha (PPARalpha): at the crossroads of obesity, diabetes and cardiovascular disease.
Atherosclerosis 2009;205(1):1-8.
2009: Brunham Liam R; Singaraja Roshni R; Duong MyNgan; Timmins Jenelle M; Fievet Catherine; Bissada Nagat; Kang Martin H; Samra Amrit; Fruchart Jean-Charles; McManus Bruce; Staels Bart; Parks John S; Hayden Michael R
Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(4):548-54.
2009: Helleboid-Chapman Audrey; Nowak Maxime; Helleboid Stéphane; Moitrot Emmanuelle; Rommens Corinne; Dehondt Hélène; Héliot Laurent; Drobecq Hervé; Fruchart-Najib Jamila; Fruchart Jean-Charles
Apolipoprotein A-V modulates insulin secretion in pancreatic beta-cells through its interaction with midkine.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009;24(5-6):451-60.
2008: Bultel Stephanie; Helin Lionel; Clavey Veronique; Chinetti-Gbaguidi Giulia; Rigamonti Elena; Colin Morvane; Fruchart Jean-Charles; Staels Bart; Lestavel Sophie
Liver X receptor activation induces the uptake of cholesteryl esters from high density lipoproteins in primary human macrophages.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(12):2288-95.
2008: Fruchart Jean-Charles; Sacks Frank; Hermans Michel P; Assmann Gerd; Brown W Virgil; Ceska Richard; Chapman M John; Dodson Paul M; Fioretto Paola; Ginsberg Henry N; Kadowaki Takashi; Lablanche Jean-Marc; Marx Nikolaus; Plutzky Jorge; Reiner Zeljko; Rosenson Robert S; Staels Bart; Stock Jane K; Sy Rody; Wanner Christoph; Zambon Alberto; Zimmet Paul
The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia.
The American journal of cardiology 2008;102(10 Suppl):1K-34K.
2008: Fruchart Jean-Charles; Sacks Frank M; Hermans Michel P; Assmann Gerd; Brown W Virgil; Ceska Richard; Chapman M John; Dodson Paul M; Fioretto Paola; Ginsberg Henry N; Kadowaki Takashi; Lablanche Jean-Marc; Marx Nikolaus; Plutzky Jorge; Reiner Zeljko; Rosenson Robert S; Staels Bart; Stock Jane K; Sy Rody; Wanner Christoph; Zambon Alberto; Zimmet Paul;
The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in dyslipidaemic patient.
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease 2008;5(4):319-35.
2008: Gineste Romain; Sirvent Audrey; Paumelle Réjane; Helleboid Stéphane; Aquilina Alexis; Darteil Raphaël; Hum Dean W; Fruchart Jean-Charles; Staels Bart
Phosphorylation of farnesoid X receptor by protein kinase C promotes its transcriptional activity.
Molecular endocrinology (Baltimore, Md.) 2008;22(11):2433-47.
2008: Mansouri Roxane M; Baugé Eric; Gervois Philippe; Fruchart-Najib Jamila; Fiévet Catherine; Staels Bart; Fruchart Jean-Charles
Atheroprotective effect of human apolipoprotein A5 in a mouse model of mixed dyslipidemia.
Circulation research 2008;103(5):450-3.
2008: Fontaine Coralie; Rigamonti Elena; Pourcet Benoit; Duez Hélène; Duhem Christian; Fruchart Jean-Charles; Chinetti-Gbaguidi Giulia; Staels Bart
The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages.
Molecular endocrinology (Baltimore, Md.) 2008;22(8):1797-811.
2008: Nowak Maxime; Helleboid-Chapman Audrey; Jakel Heidelinde; Moitrot Emmanuelle; Rommens Corinne; Pennacchio Len A; Fruchart-Najib Jamila; Fruchart Jean-Charles
Glucose regulates the expression of the apolipoprotein A5 gene.
Journal of molecular biology 2008;380(5):789-98.
2008: Billiet L; Furman C; Larigauderie G; Copin C; Page S; Fruchart J-C; Brand K; Rouis M
Enhanced VDUP-1 gene expression by PPARgamma agonist induces apoptosis in human macrophage.
Journal of cellular physiology 2008;214(1):183-91.
2007: Fruchart Jean-Charles
Novel peroxisome proliferator activated receptor-alpha agonists.
The American journal of cardiology 2007;100(11 A):n41-6.
2007: Quéméneur Thomas; Martin-Nizard Françoise; Kandoussi Abdelmejid; Kyndt Xavier; Vanhille Philippe; Hachulla Eric; Hatron Pierre-Yves; Fruchart Jean-Charles; Duriez Patrick; Lambert Marc
PON1, a new biomarker of cardiovascular disease, is low in patients with systemic vasculitis.
Seminars in arthritis and rheumatism 2007;37(3):149-55.
2007: Cariou Bertrand; Bouchaert Emmanuel; Abdelkarim Mouaadh; Dumont Julie; Caron Sandrine; Fruchart Jean-Charles; Burcelin Rémy; Kuipers Folkert; Staels Bart
FXR-deficiency confers increased susceptibility to torpor.
FEBS letters 2007;581(27):5191-8.
2007: Barter Philip; Gotto Antonio M; LaRosa John C; Maroni Jaman; Szarek Michael; Grundy Scott M; Kastelein John J P; Bittner Vera; Fruchart Jean-Charles;
HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events.
The New England journal of medicine 2007;357(13):1301-10.
2007: Yamazaki Yukiyoshi; Abe Kazutoyo; Toma Tsutomu; Nishikawa Masahiro; Ozawa Hidefumi; Okuda Ayumu; Araki Takaaki; Oda Soichi; Inoue Keisuke; Shibuya Kimiyuki; Staels Bart; Fruchart Jean-Charles
Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor alpha agonists.
Bioorganic & medicinal chemistry letters 2007;17(16):4689-93.
2007: Kahri Juhani; Fruchart-Najib Jamila; Matikainen Niina; Fruchart Jean-Charles; Vakkilainen Juha; Taskinen Marja-Riitta
The increase of apolipoprotein A-V during postprandial lipemia parallels the response of triglyceride-rich lipoproteins in type 2 diabetes: no relationship between apoA-V and postheparin plasma lipolytic activity.
Diabetes care 2007;30(8):2083-5.
2007: Rubenstrunk Anne; Hanf Rémy; Hum Dean W; Fruchart Jean-Charles; Staels Bart
Safety issues and prospects for future generations of PPAR modulators.
Biochimica et biophysica acta 2007;1771(8):1065-81.
2007: Fontaine Coralie; Rigamonti Elena; Nohara Atsushi; Gervois Philippe; Teissier Elisabeth; Fruchart Jean-Charles; Staels Bart; Chinetti-Gbaguidi Giulia
Liver X receptor activation potentiates the lipopolysaccharide response in human macrophages.
Circulation research 2007;101(1):40-9.
2007: Brigadeau François; Gelé Patrick; Wibaux Maud; Marquié Christelle; Martin-Nizard Françoise; Torpier Gérard; Fruchart Jean-Charles; Staels Bart; Duriez Patrick; Lacroix Dominique
The PPARalpha activator fenofibrate slows down the progression of the left ventricular dysfunction in porcine tachycardia-induced cardiomyopathy.
Journal of cardiovascular pharmacology 2007;49(6):408-15.
2007: Fruchart Jean-Charles
Is lipoprotein(a) a clinically meaningful risk marker for cardiovascular events in healthy women?
Nature clinical practice. Cardiovascular medicine 2007;4(5):242-3.
2007: Gervois Philippe; Fruchart Jean-Charles; Staels Bart
Drug Insight: mechanisms of action and therapeutic applications for agonists of peroxisome proliferator-activated receptors.
Nature clinical practice. Endocrinology & metabolism 2007;3(2):145-56.
2007: Niculescu Loredan Stefan; Fruchart-Najib Jamila; Fruchart Jean-Charles; Sima Anca
Apolipoprotein A-V gene polymorphisms in subjects with metabolic syndrome.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2007;45(9):1133-9.
2007: Fievet Catherine; Fruchart Jean-Charles; Staels Bart
Genetically-engineered animals as research models for atherosclerosis: their use for the characterization of PPAR agonists in the treatment of cardiometabolic disorders.
Frontiers in bioscience : a journal and virtual library 2007;12():4132-56.
2006: Bordet R; Ouk T; Petrault O; Gelé P; Gautier S; Laprais M; Deplanque D; Duriez P; Staels B; Fruchart J C; Bastide M
PPAR: a new pharmacological target for neuroprotection in stroke and neurodegenerative diseases.
Biochemical Society transactions 2006;34(Pt 6):1341-6.
2006: Lalloyer Fanny; Fiévet Catherine; Lestavel Sophie; Torpier Gérard; van der Veen Jelske; Touche Véronique; Bultel Stéphanie; Yous Saïd; Kuipers Folkert; Paumelle Réjane; Fruchart Jean-Charles; Staels Bart; Tailleux Anne
The RXR agonist bexarotene improves cholesterol homeostasis and inhibits atherosclerosis progression in a mouse model of mixed dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(12):2731-7.
2006: Fiévet Catherine; Fruchart Jean-Charles; Staels Bart
PPARalpha and PPARgamma dual agonists for the treatment of type 2 diabetes and the metabolic syndrome.
Current opinion in pharmacology 2006;6(6):606-14.
2006: Waters David D; LaRosa John C; Barter Philip; Fruchart Jean-Charles; Gotto Antonio M; Carter Roddy; Breazna Andrei; Kastelein John J P; Grundy Scott M
Effects of high-dose atorvastatin on cerebrovascular events in patients with stable coronary disease in the TNT (treating to new targets) study.
Journal of the American College of Cardiology 2006;48(9):1793-9.
2006: Larigauderie Guilhem; Bouhlel Mohamed Amine; Furman Christophe; Jaye Michael; Fruchart Jean-Charles; Rouis Mustapha
Perilipin, a potential substitute for adipophilin in triglyceride storage in human macrophages.
Atherosclerosis 2006;189(1):142-8.
2006: Deedwania Prakash; Barter Philip; Carmena Rafael; Fruchart Jean-Charles; Grundy Scott M; Haffner Steven; Kastelein John J P; LaRosa John C; Schachner Holly; Shepherd James; Waters David D;
Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: analysis of the Treating to New Targets study.
Lancet 2006;368(9539):919-28.
2006: Singaraja Roshni R; Van Eck Miranda; Bissada Nagat; Zimetti Francesca; Collins Heidi L; Hildebrand Reeni B; Hayden Anna; Brunham Liam R; Kang Martin H; Fruchart Jean-Charles; Van Berkel Theo J C; Parks John S; Staels Bart; Rothblat George H; Fiévet Catherine; Hayden Michael R
Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo.
Circulation 2006;114(12):1301-9.
2006: Pourcet Benoit; Fruchart Jean-Charles; Staels Bart; Glineur Corine
Selective PPAR modulators, dual and pan PPAR agonists: multimodal drugs for the treatment of type 2 diabetes and atherosclerosis.
Expert opinion on emerging drugs 2006;11(3):379-401.
2006: Larigauderie Guilhem; Cuaz-Pérolin Clarisse; Younes Amena B; Furman Christophe; Lasselin Catherine; Copin Corinne; Jaye Michael; Fruchart Jean-Charles; Rouis Mustapha
Adipophilin increases triglyceride storage in human macrophages by stimulation of biosynthesis and inhibition of beta-oxidation.
The FEBS journal 2006;273(15):3498-510.
2006: Helleboid-Chapman Audrey; Helleboid Stéphane; Jakel Heidelinde; Timmerman Catherine; Sergheraert Christian; Pattou François; Fruchart-Najib Jamila; Fruchart Jean-Charles
Glucose regulates LXRalpha subcellular localization and function in rat pancreatic beta-cells.
Cell research 2006;16(7):661-70.
2006: Shepherd James; Barter Philip; Carmena Rafael; Deedwania Prakash; Fruchart Jean-Charles; Haffner Steven; Hsia Judith; Breazna Andrei; LaRosa John; Grundy Scott; Waters David
Effect of lowering LDL cholesterol substantially below currently recommended levels in patients with coronary heart disease and diabetes: the Treating to New Targets (TNT) study.
Diabetes care 2006;29(6):1220-6.
2006: Lalloyer Fanny; Vandewalle Brigitte; Percevault Frédéric; Torpier Gérard; Kerr-Conte Julie; Oosterveer Maaike; Paumelle Réjane; Fruchart Jean-Charles; Kuipers Folkert; Pattou François; Fiévet Catherine; Staels Bart
Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.
Diabetes 2006;55(6):1605-13.
2006: Pérez-Méndez Oscar; Duhal Nathalie; Lacroix Brigitte; Bonte Jean-Paul; Fruchart Jean-Charles; Luc Gérald
Different VLDL apo B, and HDL apo AI and apo AII metabolism in two heterozygous carriers of unrelated mutations in the lipoprotein lipase gene.
Clinica chimica acta; international journal of clinical chemistry 2006;368(1-2):149-54.
2006: Mezdour Hafid; Larigauderie Guilhem; Castro Graciela; Torpier Gerard; Fruchart Jamila; Nowak Maxime; Fruchart Jean-Charles; Rouis Mustapha; Maeda Nobuyo
Characterization of a new mouse model for human apolipoprotein A-I/C-III/A-IV deficiency.
Journal of lipid research 2006;47(5):912-20.
2006: Zambon Alberto; Gervois Philippe; Pauletto Paolo; Fruchart Jean-Charles; Staels Bart
Modulation of hepatic inflammatory risk markers of cardiovascular diseases by PPAR-alpha activators: clinical and experimental evidence.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(5):977-86.
2006: Sparatore Anna; Godio Cristina; Perrino Elena; Romeo Sergio; Staels Bart; Fruchart Jean-Charles; Crestani Maurizio
[4-(2H-1,2,3-benzotriazol-2-yl)phenoxy]alkanoic acids as agonists of peroxisome proliferator-activated receptors (PPARs).
Chemistry & biodiversity 2006;3(4):385-95.
2006: Zamble Alexis; Carpentier Marie; Kandoussi Abdelmejid; Sahpaz Sevser; Petrault Olivier; Ouk Tawarak; Hennuyer Nathalie; Fruchart Jean-Charles; Staels Bart; Bordet Régis; Duriez Patrick; Bailleul François; Martin-Nizard Françoise
Paullinia pinnata extracts rich in polyphenols promote vascular relaxation via endothelium-dependent mechanisms.
Journal of cardiovascular pharmacology 2006;47(4):599-608.
2006: Nissen Steven E; Nicholls Stephen J; Sipahi Ilke; Libby Peter; Raichlen Joel S; Ballantyne Christie M; Davignon Jean; Erbel Raimund; Fruchart Jean Charles; Tardif Jean-Claude; Schoenhagen Paul; Crowe Tim; Cain Valerie; Wolski Kathy; Goormastic Marlene; Tuzcu E Murat;
Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial.
JAMA : the journal of the American Medical Association 2006;295(13):1556-65.
2006: Cariou Bertrand; van Harmelen Kirsten; Duran-Sandoval Daniel; van Dijk Theo H; Grefhorst Aldo; Abdelkarim Mouaadh; Caron Sandrine; Torpier Gérard; Fruchart Jean-Charles; Gonzalez Frank J; Kuipers Folkert; Staels Bart
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.
The Journal of biological chemistry 2006;281(16):11039-49.
2006: Luc Gérald; Bard Jean-Marie; Lesueur Céline; Arveiler Dominique; Evans Alun; Amouyel Philippe; Ferrieres Jean; Juhan-Vague Irène; Fruchart Jean-Charles; Ducimetiere Pierre;
Plasma cystatin-C and development of coronary heart disease: The PRIME Study.
Atherosclerosis 2006;185(2):375-80.
2006: Jakel Heidelinde; Fruchart-Najib Jamila; Fruchart Jean-Charles
Retinoic acid receptor-related orphan receptor alpha as a therapeutic target in the treatment of dyslipidemia and atherosclerosis.
Drug news & perspectives 2006;19(2):91-7.
2006: Lefebvre Philippe; Chinetti Giulia; Fruchart Jean-Charles; Staels Bart
Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis.
The Journal of clinical investigation 2006;116(3):571-80.
2006: Bordet R; Gelé P; Duriez P; Fruchart J-C
PPARs: a new target for neuroprotection.
Journal of neurology, neurosurgery, and psychiatry 2006;77(3):285-7.
2006: Duval Caroline; Touche Véronique; Tailleux Anne; Fruchart Jean-Charles; Fievet Catherine; Clavey Véronique; Staels Bart; Lestavel Sophie
Niemann-Pick C1 like 1 gene expression is down-regulated by LXR activators in the intestine.
Biochemical and biophysical research communications 2006;340(4):1259-63.
2006: Paumelle Réjane; Blanquart Christophe; Briand Olivier; Barbier Olivier; Duhem Christian; Woerly Gaëtane; Percevault Frédéric; Fruchart Jean-Charles; Dombrowicz David; Glineur Corine; Staels Bart
Acute antiinflammatory properties of statins involve peroxisome proliferator-activated receptor-alpha via inhibition of the protein kinase C signaling pathway.
Circulation research 2006;98(3):361-9.
2006: Fruchart Jean-Charles; Duriez Patrick
Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism.
Drugs of today (Barcelona, Spain : 1998) 2006;42(1):39-64.
2006: Cuaz-Pérolin Clarisse; Jguirim Imen; Larigauderie Guilhem; Jlassi Awatef; Furman Christophe; Moreau Martine; Chapman M John; Fruchart Jean-Charles; Slimane Mohamed Naceur; Mezdour Hafid; Rouis Mustapha
Apolipoprotein E knockout mice over-expressing human tissue inhibitor of metalloproteinase 1 are protected against aneurysm formation but not against atherosclerotic plaque development.
Journal of vascular research 2006;43(6):493-501.
2006: Jakel Heidelinde; Nowak Maxime; Helleboid-Chapman Audrey; Fruchart-Najib Jamila; Fruchart Jean-Charles
Is apolipoprotein A5 a novel regulator of triglyceride-rich lipoproteins?
Annals of medicine 2006;38(1):2-10.
2005: Billiet Ludivine; Furman Christophe; Larigauderie Guilhem; Copin Corinne; Brand Korbinian; Fruchart Jean-Charles; Rouis Mustapha
Extracellular human thioredoxin-1 inhibits lipopolysaccharide-induced interleukin-1beta expression in human monocyte-derived macrophages.
The Journal of biological chemistry 2005;280(48):40310-8.
2005: Chinetti-Gbaguidi G; Rigamonti E; Helin L; Mutka A L; Lepore M; Fruchart J C; Clavey V; Ikonen E; Lestavel S; Staels B
Peroxisome proliferator-activated receptor alpha controls cellular cholesterol trafficking in macrophages.
Journal of lipid research 2005;46(12):2717-25.
2005: Gizard Florence; Amant Carole; Barbier Olivier; Bellosta Stefano; Robillard Romain; Percevault Frédéric; Sevestre Henry; Krimpenfort Paul; Corsini Alberto; Rochette Jacques; Glineur Corine; Fruchart Jean-Charles; Torpier Gérard; Staels Bart
PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a.
The Journal of clinical investigation 2005;115(11):3228-38.
2005: Dumont Laure; Gautier Thomas; de Barros Jean-Paul Pais; Laplanche Hélène; Blache Denis; Ducoroy Patrick; Fruchart Jamila; Fruchart Jean-Charles; Gambert Philippe; Masson David; Lagrost Laurent
Molecular mechanism of the blockade of plasma cholesteryl ester transfer protein by its physiological inhibitor apolipoprotein CI.
The Journal of biological chemistry 2005;280(45):38108-16.
2005: Assmann Gerd; Cullen Paul; Fruchart Jean-Charles; Greten Heiner; Naruszewicz Marek; Olsson Anders; Paoletti Rodolfo; Riesen Walter; Stoll Monika; Tikkanen Matti; von Eckardstein Arnold;
Implications of emerging risk factors for therapeutic intervention.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2005;15(5):373-81.
2005: Marçais Christophe; Verges Bruno; Charrière Sybil; Pruneta Valérie; Merlin Micheline; Billon Stéphane; Perrot Laurence; Drai Jocelyne; Sassolas Agnès; Pennacchio Len A; Fruchart-Najib Jamila; Fruchart Jean-Charles; Durlach Vincent; Moulin Philippe
Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment.
The Journal of clinical investigation 2005;115(10):2862-9.
2005: Rigamonti E; Helin L; Lestavel S; Mutka A L; Lepore M; Fontaine C; Bouhlel M A; Bultel S; Fruchart J C; Ikonen E; Clavey V; Staels B; Chinetti-Gbaguidi G
Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages.
Circulation research 2005;97(7):682-9.
2005: Tailleux Anne; Gozzo Andrea; Torpier Gérard; Martin-Nizard Françoise; Bonnefont-Rousselot Dominique; Lemdani Mohamed; Furman Christophe; Foricher Rachel; Chevé Gwenaël; Yous Saïd; Micard Florence; Bordet Régis; Gardes-Albert Monique; Lesieur Daniel; Teissier Elisabeth; Fruchart Jean-Charles; Fiévet Catherine; Duriez Patrick
Increased susceptibility of low-density lipoprotein to ex vivo oxidation in mice transgenic for human apolipoprotein B treated with 1 melatonin-related compound is not associated with atherosclerosis progression.
Journal of cardiovascular pharmacology 2005;46(3):241-9.
2005: Chinetti-Gbaguidi Giulia; Fruchart Jean Charles; Staels Bart
Pleiotropic effects of fibrates.
Current atherosclerosis reports 2005;7(5):396-401.
2005: Hennuyer Nathalie; Tailleux Anne; Torpier Gérard; Mezdour Hafid; Fruchart Jean-Charles; Staels Bart; Fiévet Catherine
PPARalpha, but not PPARgamma, activators decrease macrophage-laden atherosclerotic lesions in a nondiabetic mouse model of mixed dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(9):1897-902.
2005: Pinelli Alessandra; Godio Cristina; Laghezza Antonio; Mitro Nico; Fracchiolla Giuseppe; Tortorella Vincenzo; Lavecchia Antonio; Novellino Ettore; Fruchart Jean-Charles; Staels Bart; Crestani Maurizio; Loiodice Fulvio
Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARalpha and PPARgamma agonist activity.
Journal of medicinal chemistry 2005;48(17):5509-19.
2005: Staels Bart; Fruchart Jean-Charles
Therapeutic roles of peroxisome proliferator-activated receptor agonists.
Diabetes 2005;54(8):2460-70.
2005: Cariou Bertrand; van Harmelen Kirsten; Duran-Sandoval Daniel; van Dijk Theo; Grefhorst Aldo; Bouchaert Emmanuel; Fruchart Jean-Charles; Gonzalez Frank J; Kuipers Folkert; Staels Bart
Transient impairment of the adaptive response to fasting in FXR-deficient mice.
FEBS letters 2005;579(19):4076-80.
2005: Duran-Sandoval Daniel; Cariou Bertrand; Percevault Fredéric; Hennuyer Nathalie; Grefhorst Aldo; van Dijk Theo H; Gonzalez Frank J; Fruchart Jean-Charles; Kuipers Folkert; Staels Bart
The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition.
The Journal of biological chemistry 2005;280(33):29971-9.
2005: Hiukka Anne; Fruchart-Najib Jamila; Leinonen Eeva; Hilden Hannele; Fruchart Jean-Charles; Taskinen Marja-Riitta
Alterations of lipids and apolipoprotein CIII in very low density lipoprotein subspecies in type 2 diabetes.
Diabetologia 2005;48(6):1207-15.
2005: Genoux Annelise; Dehondt Hélène; Helleboid-Chapman Audrey; Duhem Christian; Hum Dean W; Martin Geneviève; Pennacchio Len A; Staels Bart; Fruchart-Najib Jamila; Fruchart Jean-Charles
Transcriptional regulation of apolipoprotein A5 gene expression by the nuclear receptor RORalpha.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(6):1186-92.
2005: Coutinho Jonathan M; Singaraja Roshni R; Kang Martin; Arenillas David J; Bertram Lisa N; Bissada Nagat; Staels Bart; Fruchart Jean-Charles; Fievet Catherine; Joseph-George Ann M; Wasserman Wyeth W; Hayden Michael R
Complete functional rescue of the ABCA1-/- mouse by human BAC transgenesis.
Journal of lipid research 2005;46(6):1113-23.
2005: Quilliot Didier; Walters Evelyne; Bonte Jean-Paul; Fruchart Jean-Charles; Duriez Patrick; Ziegler Olivier
Diabetes mellitus worsens antioxidant status in patients with chronic pancreatitis.
The American journal of clinical nutrition 2005;81(5):1117-25.
2005: Chinetti-Gbaguidi Giulia; Fruchart Jean-Charles; Staels Bart
Role of the PPAR family of nuclear receptors in the regulation of metabolic and cardiovascular homeostasis: new approaches to therapy.
Current opinion in pharmacology 2005;5(2):177-83.
2005: LaRosa John C; Grundy Scott M; Waters David D; Shear Charles; Barter Philip; Fruchart Jean-Charles; Gotto Antonio M; Greten Heiner; Kastelein John J P; Shepherd James; Wenger Nanette K;
Intensive lipid lowering with atorvastatin in patients with stable coronary disease.
The New England journal of medicine 2005;352(14):1425-35.
2005: Duez Hélène; Lefebvre Bruno; Poulain Philippe; Torra Inés Pineda; Percevault Frédéric; Luc Gérald; Peters Jeffrey M; Gonzalez Frank J; Gineste Romain; Helleboid Stéphane; Dzavik Vladimir; Fruchart Jean-Charles; Fiévet Catherine; Lefebvre Philippe; Staels Bart
Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator-activated receptor alpha modulation.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(3):585-91.
2005: Nowak Maxime; Helleboid-Chapman Audrey; Jakel Heidelinde; Martin Geneviève; Duran-Sandoval Daniel; Staels Bart; Rubin Edward M; Pennacchio Len A; Taskinen Marja-Riitta; Fruchart-Najib Jamila; Fruchart Jean-Charles
Insulin-mediated down-regulation of apolipoprotein A5 gene expression through the phosphatidylinositol 3-kinase pathway: role of upstream stimulatory factor.
Molecular and cellular biology 2005;25(4):1537-48.
2005: Duran-Sandoval Daniel; Cariou Bertrand; Fruchart Jean-Charles; Staels Bart
Potential regulatory role of the farnesoid X receptor in the metabolic syndrome.
Biochimie 2005;87(1):93-8.
2005: Barbier Olivier; Girard Hugo; Inoue Yusuke; Duez Hélène; Villeneuve Lyne; Kamiya Akihide; Fruchart Jean-Charles; Guillemette Chantal; Gonzalez Frank J; Staels Bart
Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha.
Molecular pharmacology 2005;67(1):241-9.
2005: Robillard R; Fontaine C; Chinetti G; Fruchart J C; Staels B
Fibrates.
Handbook of experimental pharmacology 2005;(170):389-406.
2004: Martin-Nizard Françoise; Sahpaz Sevser; Kandoussi Abdelmejid; Carpentier Marie; Fruchart Jean-Charles; Duriez Patrick; Bailleul François
Natural phenylpropanoids inhibit lipoprotein-induced endothelin-1 secretion by endothelial cells.
The Journal of pharmacy and pharmacology 2004;56(12):1607-11.
2004: Teissier Elisabeth; Nohara Atsushi; Chinetti Giulia; Paumelle Réjane; Cariou Bertrand; Fruchart Jean-Charles; Brandes Ralf P; Shah Ajay; Staels Bart
Peroxisome proliferator-activated receptor alpha induces NADPH oxidase activity in macrophages, leading to the generation of LDL with PPAR-alpha activation properties.
Circulation research 2004;95(12):1174-82.
2004: Sirvent Audrey; Verhoeven Adrie J M; Jansen Hans; Kosykh Vladimir; Darteil Raphaël J; Hum Dean W; Fruchart Jean-Charles; Staels Bart
Farnesoid X receptor represses hepatic lipase gene expression.
Journal of lipid research 2004;45(11):2110-5.
2004: Brites Fernando; Verona Julián; De Geitere Catherine; Fruchart Jean-Charles; Castro Graciela; Wikinski Regina
Enhanced cholesterol efflux promotion in well-trained soccer players.
Metabolism: clinical and experimental 2004;53(10):1262-7.
2004: Jakel Heidelinde; Nowak Maxime; Moitrot Emanuelle; Dehondt Hélène; Hum Dean W; Pennacchio Len A; Fruchart-Najib Jamila; Fruchart Jean-Charles
The liver X receptor ligand T0901317 down-regulates APOA5 gene expression through activation of SREBP-1c.
The Journal of biological chemistry 2004;279(44):45462-9.
2004: Cuaz-Pérolin C; Furman C; Larigauderie G; Legedz L; Lasselin C; Copin C; Jaye M; Searfoss G; Yu K T; Duverger N; Nègre-Salvayre A; Fruchart J-C; Rouis M
REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1830-5.
2004: Barbier Olivier; Fontaine Coralie; Fruchart Jean-Charles; Staels Bart
Genomic and non-genomic interactions of PPARalpha with xenobiotic-metabolizing enzymes.
Trends in endocrinology and metabolism: TEM 2004;15(7):324-30.
2004: Chapman M John; Assmann Gerd; Fruchart Jean-Charles; Shepherd James; Sirtori Cesare;
Raising high-density lipoprotein cholesterol with reduction of cardiovascular risk: the role of nicotinic acid--a position paper developed by the European Consensus Panel on HDL-C.
Current medical research and opinion 2004;20(8):1253-68.
2004: Kosoglou Teddy; Statkevich Paul; Fruchart Jean-Charles; Pember Laura J C; Reyderman Larisa; Cutler David L; Guillaume Michel; Maxwell Stephen E; Veltri Enrico P
Pharmacodynamic and pharmacokinetic interaction between fenofibrate and ezetimibe.
Current medical research and opinion 2004;20(8):1197-207.
2004: Blanquart Christophe; Mansouri Roxane; Paumelle Réjane; Fruchart Jean-Charles; Staels Bart; Glineur Corine
The protein kinase C signaling pathway regulates a molecular switch between transactivation and transrepression activity of the peroxisome proliferator-activated receptor alpha.
Molecular endocrinology (Baltimore, Md.) 2004;18(8):1906-18.
2004: Brites F; Verona J; Fernández K; Henriksen F; Fruchart J; Cesar M; Castro G; Wikinski R
HDL metabolic activities in a boy with lipoprotein lipase deficiency and his family.
European journal of clinical investigation 2004;34(7):467-74.
2004: Briand Olivier; Nizard Françoise Martin; David-Dufilho Monique; Six Isabelle; Lestavel Sophie; Brunet Annie; Fruchart Jean-Charles; Torpier Gérard; Bordet Régis; Clavey Véronique; Duriez Patrick
Human free apolipoprotein A-I and artificial pre-beta-high-density lipoprotein inhibit eNOS activity and NO release.
Biochimica et biophysica acta 2004;1683(1-3):69-77.
2004: Furman C; Rundlöf A-K; Larigauderie G; Jaye M; Bricca G; Copin C; Kandoussi A M; Fruchart J-C; Arnér E S J; Rouis M
Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: specific induction of the promoter in human macrophages by oxidized low-density lipoproteins.
Free radical biology & medicine 2004;37(1):71-85.
2004: Baroukh Nadine; Bauge Eric; Akiyama Jennifer; Chang Jessie; Afzal Veena; Fruchart Jean-Charles; Rubin Edward M; Fruchart-Najib Jamila; Pennacchio Len A
Analysis of apolipoprotein A5, c3, and plasma triglyceride concentrations in genetically engineered mice.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(7):1297-302.
2004: de Groot Eric; Hovingh G Kees; Wiegman Albert; Duriez Patrick; Smit Andries J; Fruchart Jean-Charles; Kastelein John J P
Measurement of arterial wall thickness as a surrogate marker for atherosclerosis.
Circulation 2004;109(23 Suppl 1):III33-8.
2004: Fruchart Jean-Charles; Nierman Melchior C; Stroes Erik S G; Kastelein John J P; Duriez Patrick
New risk factors for atherosclerosis and patient risk assessment.
Circulation 2004;109(23 Suppl 1):III15-9.
2004: Carmena Rafael; Duriez Patrick; Fruchart Jean-Charles
Atherogenic lipoprotein particles in atherosclerosis.
Circulation 2004;109(23 Suppl 1):III2-7.
2004: Blanquart Christophe; Mansouri Roxane; Fruchart Jean-Charles; Staels Bart; Glineur Corine
Different ways to regulate the PPARalpha stability.
Biochemical and biophysical research communications 2004;319(2):663-70.
2004: Fruchart-Najib Jamila; Baugé Eric; Niculescu Loredan-Stefan; Pham Tatiana; Thomas Benoit; Rommens Corinne; Majd Zouher; Brewer Bryan; Pennacchio Len A; Fruchart Jean-Charles
Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5.
Biochemical and biophysical research communications 2004;319(2):397-404.
2004: Brites Fernando Daniel; Verona Julián; Schreier Laura Ester; Fruchart Jean-Charles; Castro Graciela Rosa; Wikinski Regina Luisa
Paraoxonase 1 and platelet-activating factor acetylhydrolase activities in patients with low hdl-cholesterol levels with or without primary hypertriglyceridemia.
Archives of medical research 2004;35(3):235-40.
2004: Sirvent Audrey; Claudel Thierry; Martin Geneviève; Brozek John; Kosykh Vladimir; Darteil Raphaël; Hum Dean W; Fruchart Jean-Charles; Staels Bart
The farnesoid X receptor induces very low density lipoprotein receptor gene expression.
FEBS letters 2004;566(1-3):173-7.
2004: Marx Nikolaus; Duez Hélène; Fruchart Jean-Charles; Staels Bart
Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells.
Circulation research 2004;94(9):1168-78.
2004: Furman Christophe; Copin Corinne; Kandoussi Mejid; Davidson Robert; Moreau Martine; McTaggiart Fergus; Chapman M John; Fruchart Jean-Charles; Rouis Mustapha
Rosuvastatin reduces MMP-7 secretion by human monocyte-derived macrophages: potential relevance to atherosclerotic plaque stability.
Atherosclerosis 2004;174(1):93-8.
2004: de Grooth Greetje J; Smilde Tineke J; Van Wissen Sanne; Klerkx Anke H E M; Zwinderman Aeilko H; Fruchart Jean-Charles; Kastelein John J P; Stalenhoef Anton F H; Kuivenhoven Jan Albert
The relationship between cholesteryl ester transfer protein levels and risk factor profile in patients with familial hypercholesterolemia.
Atherosclerosis 2004;173(2):261-7.
2004: Duran-Sandoval Daniel; Mautino Gisèle; Martin Geneviève; Percevault Fréderic; Barbier Olivier; Fruchart Jean-Charles; Kuipers Folkert; Staels Bart
Glucose regulates the expression of the farnesoid X receptor in liver.
Diabetes 2004;53(4):890-8.
2004: Luc Gérald; Jacob Nelly; Bouly Muriel; Fruchart Jean-Charles; Staels Bart; Giral Philippe
Fenofibrate increases homocystinemia through a PPARalpha-mediated mechanism.
Journal of cardiovascular pharmacology 2004;43(3):452-3.
2004: Welch Carrie L; Bretschger Sara; Wen Ping-Zi; Mehrabian Margarete; Latib Nashat; Fruchart-Najib Jamila; Fruchart Jean Charles; Myrick Christy; Lusis Aldons J
Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain.
Physiological genomics 2004;17(1):48-59.
2004: Larigauderie Guilhem; Furman Christophe; Jaye Michael; Lasselin Catherine; Copin Corinne; Fruchart Jean-Charles; Castro Graciela; Rouis Mustapha
Adipophilin enhances lipid accumulation and prevents lipid efflux from THP-1 macrophages: potential role in atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(3):504-10.
2004: Baroukh Nadine; Lopez Camilo E; Saleh Maria Carla; Recalde Delia; Vergnes Laurent; Ostos Maria A; Fiette Laurence; Fruchart Jean-Charles; Castro Graciela; Zakin Mario M; Ochoa Alberto
Expression and secretion of human apolipoprotein A-I in the heart.
FEBS letters 2004;557(1-3):39-44.
2003: Kuivenhoven J A; Hovingh G K; van Tol A; Jauhiainen M; Ehnholm C; Fruchart J C; Brinton E A; Otvos J D; Smelt A H M; Brownlee A; Zwinderman A H; Hayden M R; Kastelein J J P
Heterozygosity for ABCA1 gene mutations: effects on enzymes, apolipoproteins and lipoprotein particle size.
Atherosclerosis 2003;171(2):311-9.
2003: Tailleux Anne; Torpier Gérard; Mezdour Hafid; Fruchart Jean-Charles; Staels Bart; Fiévet Catherine
Murine models to investigate pharmacological compounds acting as ligands of PPARs in dyslipidemia and atherosclerosis.
Trends in pharmacological sciences 2003;24(10):530-4.
2003: Chinetti Giulia; Fruchart Jean-Charles; Staels Bart
Peroxisome proliferator-activated receptors: new targets for the pharmacological modulation of macrophage gene expression and function.
Current opinion in lipidology 2003;14(5):459-68.
2003: Luc Gérald; Arveiler Dominique; Evans Alun; Amouyel Philippe; Ferrieres Jean; Bard Jean-Marie; Elkhalil Latifa; Fruchart Jean-Charles; Ducimetiere Pierre;
Circulating soluble adhesion molecules ICAM-1 and VCAM-1 and incident coronary heart disease: the PRIME Study.
Atherosclerosis 2003;170(1):169-76.
2003: Fruchart Jean-Charles; Bordet Régis; Duriez Patrick
Peroxisome proliferator activated receptors and stroke.
Current atherosclerosis reports 2003;5(5):331-2.
2003: Fontaine Coralie; Dubois Guillaume; Duguay Yannick; Helledie Torben; Vu-Dac Ngoc; Gervois Philippe; Soncin Fabrice; Mandrup Susanne; Fruchart Jean-Charles; Fruchart-Najib Jamila; Staels Bart
The orphan nuclear receptor Rev-Erbalpha is a peroxisome proliferator-activated receptor (PPAR) gamma target gene and promotes PPARgamma-induced adipocyte differentiation.
The Journal of biological chemistry 2003;278(39):37672-80.
2003: Duran-Sandoval Daniel; Thomas Anne-Claire; Bailleul Bernard; Fruchart Jean-Charles; Staels Bart
[Pharmacology of PPARalpha, PPARgamma and dual PPARalpha/gamma agonists in clinical development]
Médecine sciences : M/S 2003;19(8-9):819-25.
2003: Claudel Thierry; Inoue Yusuke; Barbier Olivier; Duran-Sandoval Daniel; Kosykh Vladimir; Fruchart Jamila; Fruchart Jean-Charles; Gonzalez Frank J; Staels Bart
Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression.
Gastroenterology 2003;125(2):544-55.
2003: Barbier Olivier; Duran-Sandoval Daniel; Pineda-Torra Inés; Kosykh Vladimir; Fruchart Jean-Charles; Staels Bart
Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme.
The Journal of biological chemistry 2003;278(35):32852-60.
2003: Deplanque Dominique; Gelé Patrick; Pétrault Olivier; Six Isabelle; Furman Christophe; Bouly Muriel; Nion Stéphane; Dupuis Bernard; Leys Didier; Fruchart Jean-Charles; Cecchelli Roméo; Staels Bart; Duriez Patrick; Bordet Régis
Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(15):6264-71.
2003: Luc Gérald; Bard Jean-Marie; Juhan-Vague Irène; Ferrieres Jean; Evans Alun; Amouyel Philippe; Arveiler Dominique; Fruchart Jean-Charles; Ducimetiere Pierre;
C-reactive protein, interleukin-6, and fibrinogen as predictors of coronary heart disease: the PRIME Study.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(7):1255-61.
2003: Blanquart Christophe; Barbier Olivier; Fruchart Jean Charles; Staels Bart; Glineur Corine
Peroxisome proliferator-activated receptors: regulation of transcriptional activities and roles in inflammation.
The Journal of steroid biochemistry and molecular biology 2003;85(2-5):267-73.
2003: Barbier Olivier; Torra Ines Pineda; Sirvent Audrey; Claudel Thierry; Blanquart Christophe; Duran-Sandoval Daniel; Kuipers Folkert; Kosykh Vladimir; Fruchart Jean-Charles; Staels Bart
FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity.
Gastroenterology 2003;124(7):1926-40.
2003: Romon Monique; Lebel Pascal; Fruchart Jean-Charles; Dallongeville Jean
Postprandial leptin response to carbohydrate and fat meals in obese women.
Journal of the American College of Nutrition 2003;22(3):247-51.
2003: Vu-Dac Ngoc; Gervois Philippe; Jakel Heidi; Nowak Maxime; Bauge Eric; Dehondt Helene; Staels Bart; Pennacchio Len A; Rubin Edward M; Fruchart-Najib Jamila; Fruchart Jean-Charles
Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators.
The Journal of biological chemistry 2003;278(20):17982-5.
2003: Pilon Antoine; Martin Geneviève; Bultel-Brienne Stéphanie; Junquero Didier; Delhon André; Fruchart Jean-Charles; Staels Bart; Clavey Véronique
Regulation of the scavenger receptor BI and the LDL receptor by activators of aldosterone production, angiotensin II and PMA, in the human NCI-H295R adrenocortical cell line.
Biochimica et biophysica acta 2003;1631(3):218-28.
2003: Bocher Virginie; Millatt Lesley J; Fruchart Jean-Charles; Staels Bart
Liver X receptors: new players in atherogenesis?
Current opinion in lipidology 2003;14(2):137-43.
2003: Barbier Olivier; Villeneuve Lyne; Bocher Virginie; Fontaine Coralie; Torra Ines Pineda; Duhem Christian; Kosykh Vladimir; Fruchart Jean-Charles; Guillemette Chantal; Staels Bart
The UDP-glucuronosyltransferase 1A9 enzyme is a peroxisome proliferator-activated receptor alpha and gamma target gene.
The Journal of biological chemistry 2003;278(16):13975-83.
2003: Martin-Nizard Françoise; Sahpaz Sevser; Furman Christophe; Fruchart Jean-Charles; Duriez Patrick; Bailleul François
Natural phenylpropanoids protect endothelial cells against oxidized LDL-induced cytotoxicity.
Planta medica 2003;69(3):207-11.
2003: Millatt Lesley J; Bocher Virginie; Fruchart Jean Charles; Staels Bart
Liver X receptors and the control of cholesterol homeostasis: potential therapeutic targets for the treatment of atherosclerosis.
Biochimica et biophysica acta 2003;1631(2):107-18.
2003: Quilliot D; Walters E; Böhme P; Lacroix B; Bonte J P; Fruchart J C; Drouin P; Duriez P; Ziegler O
Fatty acid abnormalities in chronic pancreatitis: effect of concomitant diabetes mellitus.
European journal of clinical nutrition 2003;57(3):496-503.
2003: Briand Olivier; Lestavel Sophie; Pilon Antoine; Torpier Gérard; Fruchart Jean-Charles; Clavey Véronique
SR-BI does not require raft/caveola localisation for cholesteryl ester selective uptake in the human adrenal cell line NCI-H295R.
Biochimica et biophysica acta 2003;1631(1):42-50.
2003: Pineda Torra Inés; Claudel Thierry; Duval Caroline; Kosykh Vladimir; Fruchart Jean-Charles; Staels Bart
Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.
Molecular endocrinology (Baltimore, Md.) 2003;17(2):259-72.
2003: Gervois Philippe; Fruchart Jean-Charles
[PPAR gamma: a major nuclear receptor in adipogenesis]
Médecine sciences : M/S 2003;19(1):20-2.
2003: Rinninger Franz; Brundert May; Budzinski Ralph-M; Fruchart Jean-Charles; Greten Heiner; Castro Graciela R
Scavenger receptor BI (SR-BI) mediates a higher selective cholesteryl ester uptake from LpA-I compared with LpA-I:A-II lipoprotein particles.
Atherosclerosis 2003;166(1):31-40.
2002: Raspé Eric; Duez Hélène; Mansén Anethe; Fontaine Coralie; Fiévet Catherine; Fruchart Jean-Charles; Vennström Bjorn; Staels Bart
Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription.
Journal of lipid research 2002;43(12):2172-9.
2002: Martin-Nizard F; Furman C; Delerive P; Kandoussi A; Fruchart J C; Staels B; Duriez P
Peroxisome proliferator-activated receptor activators inhibit oxidized low-density lipoprotein-induced endothelin-1 secretion in endothelial cells.
Journal of cardiovascular pharmacology 2002;40(6):822-31.
2002: Fruchart Jean-Charles; Duriez Patrick
HDL and triglyceride as therapeutic targets.
Current opinion in lipidology 2002;13(6):605-16.
2002: Duez Hélène; Chao Yu-Sheng; Hernandez Melba; Torpier Gérard; Poulain Philippe; Mundt Steven; Mallat Ziad; Teissier Elisabeth; Burton Charlotte A; Tedgui Alain; Fruchart Jean-Charles; Fiévet Catherine; Wright Sam D; Staels Bart
Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice.
The Journal of biological chemistry 2002;277(50):48051-7.
2002: Raspè Eric; Mautino Gisèle; Duval Caroline; Fontaine Coralie; Duez Hélène; Barbier Olivier; Monte Didier; Fruchart Jamila; Fruchart Jean-Charles; Staels Bart
Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha.
The Journal of biological chemistry 2002;277(51):49275-81.
2002: Furman C; Luo Z; Walsh K; Duverger N; Copin C; Fruchart J C; Rouis M
Systemic tissue inhibitor of metalloproteinase-1 gene delivery reduces neointimal hyperplasia in balloon-injured rat carotid artery.
FEBS letters 2002;531(2):122-6.
2002: Slimane M N; Lestavel S; Clavey V; Maatouk F; Ben Fahrat M H; Fruchart J C; Hammami M; Benlian P
CYS127S (FH-Kairouan) and D245N (FH-Tozeur) mutations in the LDL receptor gene in Tunisian families with familial hypercholesterolaemia.
Journal of medical genetics 2002;39(11):e74.
2002: Ulloa Natalia; Arteaga Eugenio; Bustos Paulina; Durán-Sandoval Daniel; Schulze Kim; Castro Graciela; Jauhiainen Matti; Fruchart Jean Charles; Calvo Carlos
Sequential estrogen-progestin replacement therapy in healthy postmenopausal women: effects on cholesterol efflux capacity and key proteins regulating high-density lipoprotein levels.
Metabolism: clinical and experimental 2002;51(11):1410-7.
2002: Fruchart Jean-Charles; Duriez Patrick
HMG CoA reductase inhibitors and PPAR-alpha activators: are their effects on high-density lipoprotein cholesterol and their pleiotropic effects clinically relevant in prevention trials?
Current atherosclerosis reports 2002;4(6):403-4.
2002: Fruchart Jean-Charles
The science behind statins and fibrates.
International journal of clinical practice. Supplement 2002;(132):11-6.
2002: Blanquart Christophe; Barbier Olivier; Fruchart Jean-Charles; Staels Bart; Glineur Corine
Peroxisome proliferator-activated receptor alpha (PPARalpha ) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes.
The Journal of biological chemistry 2002;277(40):37254-9.
2002: Fruchart Jean-Charles
[Statins for cardiovascular prevention. Lowering LDL cholesterol, the primary objective]
Presse médicale (Paris, France : 1983) 2002;31(30):1428-33.
2002: Duval Caroline; Chinetti Giulia; Trottein Francois; Fruchart Jean-Charles; Staels Bart
The role of PPARs in atherosclerosis.
Trends in molecular medicine 2002;8(9):422-30.
2002: Bonnefont-Rousselot Dominique; Chevé Gwénaël; Gozzo Andrea; Tailleux Anne; Guilloz Virginie; Caisey Stéphanie; Teissier Elisabeth; Fruchart Jean-Charles; Delattre Jacques; Jore Daniel; Lesieur Daniel; Duriez Patrick; Gardès-Albert Monique
Melatonin related compounds inhibit lipid peroxidation during copper or free radical-induced LDL oxidation.
Journal of pineal research 2002;33(2):109-17.
2002: Bultel-Brienne Stéphanie; Lestavel Sophie; Pilon Antoine; Laffont Isabelle; Tailleux Anne; Fruchart Jean-Charles; Siest Gérard; Clavey Véronique
Lipid free apolipoprotein E binds to the class B Type I scavenger receptor I (SR-BI) and enhances cholesteryl ester uptake from lipoproteins.
The Journal of biological chemistry 2002;277(39):36092-9.
2002: Tailleux Anne; Duriez Patrick; Fruchart Jean-Charles; Clavey Véronique
Apolipoprotein A-II, HDL metabolism and atherosclerosis.
Atherosclerosis 2002;164(1):1-13.
2002: Kandoussi Abdelmejid; Martin François; Hazzan Marc; Noël Christian; Fruchart Jean-Charles; Staels Bart; Duriez Patrick
HMG-CoA reductase inhibition and PPAR- alpha activation both inhibit cyclosporin A induced endothelin-1 secretion in cultured endothelial cells.
Clinical science (London, England : 1979) 2002;103 Suppl 48():81S-83S.
2002: Dallongeville Jean; Harbis Amandine; Lebel Pascal; Defoort Catherine; Lairon Denis; Fruchart Jean-Charles; Romon Monique
The plasma and lipoprotein triglyceride postprandial response to a carbohydrate tolerance test differs in lean and massively obese normolipidemic women.
The Journal of nutrition 2002;132(8):2161-6.
2002: Luc Gérald; Bard Jean-Marie; Arveiler Dominique; Ferrieres Jean; Evans Alun; Amouyel Philippe; Fruchart Jean-Charles; Ducimetiere Pierre;
Lipoprotein (a) as a predictor of coronary heart disease: the PRIME Study.
Atherosclerosis 2002;163(2):377-84.
2002: Luc Gérald; Bard Jean-Marie; Ferrières Jean; Evans Alun; Amouyel Philippe; Arveiler Dominique; Fruchart Jean-Charles; Ducimetière Pierre
Value of HDL cholesterol, apolipoprotein A-I, lipoprotein A-I, and lipoprotein A-I/A-II in prediction of coronary heart disease: the PRIME Study. Prospective Epidemiological Study of Myocardial Infarction.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(7):1155-61.
2002: Singaraja Roshni R; Fievet Catherine; Castro Graciela; James Erick R; Hennuyer Nathalie; Clee Susanne M; Bissada Nagat; Choy Jonathan C; Fruchart Jean-Charles; McManus Bruce M; Staels Bart; Hayden Michael R
Increased ABCA1 activity protects against atherosclerosis.
The Journal of clinical investigation 2002;110(1):35-42.
2002: Bocher Virginie; Pineda-Torra Ines; Fruchart Jean-Charles; Staels Bart
PPARs: transcription factors controlling lipid and lipoprotein metabolism.
Annals of the New York Academy of Sciences 2002;967():7-18.
2002: Laffont Isabelle; Shuvaev Vladimir V; Briand Olivier; Lestavel Sophie; Barbier Anne; Taniguchi Naoyuki; Fruchart Jean-Charles; Clavey Véronique; Siest Gérard
Early-glycation of apolipoprotein E: effect on its binding to LDL receptor, scavenger receptor A and heparan sulfates.
Biochimica et biophysica acta 2002;1583(1):99-107.
2002: Tailleux Anne; Torpier Gérard; Bonnefont-Rousselot Dominique; Lestavel Sophie; Lemdani Mohamed; Caudeville Bernadette; Furman Christophe; Foricher Rachel; Gardes-Albert Monique; Lesieur Daniel; Rolando Christian; Teissier Elisabeth; Fruchart Jean-Charles; Clavey Véronique; Fievet Catherine; Duriez Patrick
Daily melatonin supplementation in mice increases atherosclerosis in proximal aorta.
Biochemical and biophysical research communications 2002;293(3):1114-23.
2002: Barbier O; Torra I Pineda; Duguay Y; Blanquart C; Fruchart J-C; Glineur C; Staels B
Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(5):717-26.
2002: Delerive Philippe; De Bosscher Karolien; Vanden Berghe Wim; Fruchart Jean-Charles; Haegeman Guy; Staels Bart
DNA binding-independent induction of IkappaBalpha gene transcription by PPARalpha.
Molecular endocrinology (Baltimore, Md.) 2002;16(5):1029-39.
2002: Pineda Torra Inés; Jamshidi Yalda; Flavell David M; Fruchart Jean-Charles; Staels Bart
Characterization of the human PPARalpha promoter: identification of a functional nuclear receptor response element.
Molecular endocrinology (Baltimore, Md.) 2002;16(5):1013-28.
2002: Claudel Thierry; Sturm Ekkehard; Duez Hélène; Torra Inés Pineda; Sirvent Audrey; Kosykh Vladimir; Fruchart Jean-Charles; Dallongeville Jean; Hum Dean W; Kuipers Folkert; Staels Bart
Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element.
The Journal of clinical investigation 2002;109(7):961-71.
2002: Montoya Maria Teresa; Porres Amelia; Serrano Sagrario; Fruchart Jean Charles; Mata Pedro; Gerique Juan Antonio Gómez; Castro Graciela Rosa
Fatty acid saturation of the diet and plasma lipid concentrations, lipoprotein particle concentrations, and cholesterol efflux capacity.
The American journal of clinical nutrition 2002;75(3):484-91.
2002: Gbaguidi F G; Chinetti G; Milosavljevic D; Teissier E; Chapman J; Olivecrona G; Fruchart J C; Griglio S; Fruchart-Najib J; Staels B
Peroxisome proliferator-activated receptor (PPAR) agonists decrease lipoprotein lipase secretion and glycated LDL uptake by human macrophages.
FEBS letters 2002;512(1-3):85-90.
2002: Bocher Virginie; Chinetti Giulia; Fruchart Jean-Charles; Staels Bart
[Role of the peroxisome proliferator-activated receptors (PPARS) in the regulation of lipids and inflammation control]
Journal de la Société de biologie 2002;196(1):47-52.
2001: Asset G; Baugé E; Wolff R L; Fruchart J C; Dallongeville J
Effects of dietary maritime pine seed oil on lipoprotein metabolism and atherosclerosis development in mice expressing human apolipoprotein B.
European journal of nutrition 2001;40(6):268-74.
2001: Fruchart J C
Peroxisome proliferator-activated receptor-alpha activation and high-density lipoprotein metabolism.
The American journal of cardiology 2001;88(12A):24N-29N.
2001: Guerre-Millo M; Rouault C; Poulain P; André J; Poitout V; Peters J M; Gonzalez F J; Fruchart J C; Reach G; Staels B
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
Diabetes 2001;50(12):2809-14.
2001: Fruchart J C; Staels B; Duriez P
PPARS, metabolic disease and atherosclerosis.
Pharmacological research : the official journal of the Italian Pharmacological Society 2001;44(5):345-52.
2001: Pennacchio L A; Olivier M; Hubacek J A; Cohen J C; Cox D R; Fruchart J C; Krauss R M; Rubin E M
An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing.
Science (New York, N.Y.) 2001;294(5540):169-73.
2001: Quilliot D; Walters E; Guerci B; Fruchart J C; Duriez P; Drouin P; Ziegler O
Effect of the inflammation, chronic hyperglycemia, or malabsorption on the apolipoprotein A-IV concentration in type 1 diabetes mellitus and in diabetes secondary to chronic pancreatitis.
Metabolism: clinical and experimental 2001;50(9):1019-24.
2001: Gervois P; Vu-Dac N; Kleemann R; Kockx M; Dubois G; Laine B; Kosykh V; Fruchart J C; Kooistra T; Staels B
Negative regulation of human fibrinogen gene expression by peroxisome proliferator-activated receptor alpha agonists via inhibition of CCAAT box/enhancer-binding protein beta.
The Journal of biological chemistry 2001;276(36):33471-7.
2001: Baroukh N; Ostos M A; Vergnes L; Recalde D; Staels B; Fruchart J; Ochoa A; Castro G; Zakin M M
Expression of human apolipoprotein A-I/C-III/A-IV gene cluster in mice reduces atherogenesis in response to a high fat-high cholesterol diet.
FEBS letters 2001;502(1-2):16-20.
2001: Bouly M; Masson D; Gross B; Jiang X C; Fievet C; Castro G; Tall A R; Fruchart J C; Staels B; Lagrost L; Luc G
Induction of the phospholipid transfer protein gene accounts for the high density lipoprotein enlargement in mice treated with fenofibrate.
The Journal of biological chemistry 2001;276(28):25841-7.
2001: Martin G; Duez H; Blanquart C; Berezowski V; Poulain P; Fruchart J C; Najib-Fruchart J; Glineur C; Staels B
Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I.
The Journal of clinical investigation 2001;107(11):1423-32.
2001: Delerive P; Fruchart J C; Staels B
Peroxisome proliferator-activated receptors in inflammation control.
The Journal of endocrinology 2001;169(3):453-9.
2001: Torra I P; Chinetti G; Duval C; Fruchart J C; Staels B
Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice.
Current opinion in lipidology 2001;12(3):245-54.
2001: Asset G; Baugé E; Fruchart J C; Dallongeville J
Lack of triglyceride-lowering properties of fish oil in apolipoprotein e-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(3):401-6.
2001: Boullier A; Hennuyer N; Tailleux A; Furman C; Duverger N; Caillaud J M; Castro G; Fievet C; Fruchart J C; Duriez P
Increased levels of high-density lipoprotein cholesterol are ineffective in inhibiting the development of immune responses to oxidized low-density lipoprotein and atherosclerosis in transgenic rabbits expressing human apolipoprotein (apo) A-I with severe hypercholesterolaemia.
Clinical science (London, England : 1979) 2001;100(3):343-55.
2001: Junquero D; Pilon A; Carilla-Durand E; Patoiseau J F; Tarayre J P; Torpier G; Staels B; Fruchart J C; Colpaert F C; Clavey V; Delhon A
Lack of toxic effects of F 12511, a novel potent inhibitor of acyl-coenzyme A: cholesterol O-acyltransferase, on human adrenocortical cells in culture.
Biochemical pharmacology 2001;61(4):387-98.
2001: Dallongeville J; Baugé E; Tailleux A; Peters J M; Gonzalez F J; Fruchart J C; Staels B
Peroxisome proliferator-activated receptor alpha is not rate-limiting for the lipoprotein-lowering action of fish oil.
The Journal of biological chemistry 2001;276(7):4634-9.
2001: Delerive P; Monté D; Dubois G; Trottein F; Fruchart-Najib J; Mariani J; Fruchart J C; Staels B
The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response.
EMBO reports 2001;2(1):42-8.
2001: Neve B P; Corseaux D; Chinetti G; Zawadzki C; Fruchart J C; Duriez P; Staels B; Jude B
PPARalpha agonists inhibit tissue factor expression in human monocytes and macrophages.
Circulation 2001;103(2):207-12.
2001: Chinetti G; Lestavel S; Bocher V; Remaley A T; Neve B; Torra I P; Teissier E; Minnich A; Jaye M; Duverger N; Brewer H B; Fruchart J C; Clavey V; Staels B
PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway.
Nature medicine 2001;7(1):53-8.
2001: Raspé E; Duez H; Gervois P; Fiévet C; Fruchart J C; Besnard S; Mariani J; Tedgui A; Staels B
Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha.
The Journal of biological chemistry 2001;276(4):2865-71.
2001: Bocher V; Chinetti G; Fruchart J C; Staels B
[PPARs activators and regulation of lipid metabolism, vascular inflammation and atherosclerosis]
Journées annuelles de diabétologie de l'Hôtel-Dieu 2001;():23-32.
2000: Tailleux A; Bouly M; Luc G; Castro G; Caillaud J M; Hennuyer N; Poulain P; Fruchart J C; Duverger N; Fiévet C
Decreased susceptibility to diet-induced atherosclerosis in human apolipoprotein A-II transgenic mice.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(11):2453-8.
2000: Delerive P; Gervois P; Fruchart J C; Staels B
Induction of IkappaBalpha expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-alpha activators.
The Journal of biological chemistry 2000;275(47):36703-7.
2000: Vergnes L; Baroukh N; Ostos M A; Castro G; Duverger N; Nanjee M N; Najib J; Fruchart J C; Miller N E; Zakin M M; Ochoa A
Expression of human apolipoprotein A-I/C-III/A-IV gene cluster in mice induces hyperlipidemia but reduces atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(10):2267-74.
2000: Torra I P; Tsibulsky V; Delaunay F; Saladin R; Laudet V; Fruchart J C; Kosykh V; Staels B
Circadian and glucocorticoid regulation of Rev-erbalpha expression in liver.
Endocrinology 2000;141(10):3799-806.
2000: Neve B P; Fruchart J C; Staels B
Role of the peroxisome proliferator-activated receptors (PPAR) in atherosclerosis.
Biochemical pharmacology 2000;60(8):1245-50.
2000: Fruchart J C
Are nuclear factors the ultimate targets of drugs affecting lipid metabolism?
Current atherosclerosis reports 2000;2(5):353-4.
2000: Brites F D; Bonavita C D; De Geitere C; Cloës M; Delfly B; Yael M J; Fruchart J; Wikinski R W; Castro G R
Alterations in the main steps of reverse cholesterol transport in male patients with primary hypertriglyceridemia and low HDL-cholesterol levels.
Atherosclerosis 2000;152(1):181-92.
2000: Asset G; Leroy A; Bauge E; Wolff R L; Fruchart J C; Dallongeville J
Effects of dietary maritime pine (Pinus pinaster)-seed oil on high-density lipoprotein levels and in vitro cholesterol efflux in mice expressing human apolipoprotein A-I.
The British journal of nutrition 2000;84(3):353-60.
2000: Boullier A; Walters-Laporte E; Hamon M; Tailleux A; Amant C; Amouyel P; Fruchart J; Bertrand M; Duriez P
Absence of relationship between plasma Lp(a), Lp-AI, anti-oxidized LDL autoantibodies, LDL immune complexes concentrations and restenosis after percutaneous transluminal coronary angioplasty.
Clinica chimica acta; international journal of clinical chemistry 2000;299(1-2):129-40.
2000: Beghin L; Duhal N; Poulain P; Hauw P; Lacroix B; Lecerf J M; Bonte J P; Fruchart J C; Luc G
Measurement of apolipoprotein B concentration in plasma lipoproteins by combining selective precipitation and mass spectrometry.
Journal of lipid research 2000;41(7):1172-6.
2000: Martin G; Nemoto M; Gelman L; Geffroy S; Najib J; Fruchart J C; Roevens P; de Martinville B; Deeb S; Auwerx J
The human fatty acid transport protein-1 (SLC27A1; FATP-1) cDNA and gene: organization, chromosomal localization, and expression.
Genomics 2000;66(3):296-304.
2000: Demeester N; Castro G; Desrumaux C; De Geitere C; Fruchart J C; Santens P; Mulleners E; Engelborghs S; De Deyn P P; Vandekerckhove J; Rosseneu M; Labeur C
Characterization and functional studies of lipoproteins, lipid transfer proteins, and lecithin:cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimer's disease.
Journal of lipid research 2000;41(6):963-74.
2000: Guerre-Millo M; Gervois P; Raspé E; Madsen L; Poulain P; Derudas B; Herbert J M; Winegar D A; Willson T M; Fruchart J C; Berge R K; Staels B
Peroxisome proliferator-activated receptor alpha activators improve insulin sensitivity and reduce adiposity.
The Journal of biological chemistry 2000;275(22):16638-42.
2000: Asset G; Baugé E; Wolff R L; Fruchart J C; Dallongeville J
Comparison of maritime pine oil and fish oil effects on plasma lipoproteins in apolipoprotein E-deficient mice.
Prostaglandins, leukotrienes, and essential fatty acids 2000;62(5):307-10.
2000: Chinetti G; Gbaguidi F G; Griglio S; Mallat Z; Antonucci M; Poulain P; Chapman J; Fruchart J C; Tedgui A; Najib-Fruchart J; Staels B
CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors.
Circulation 2000;101(20):2411-7.
2000: Martin G; Poirier H; Hennuyer N; Crombie D; Fruchart J C; Heyman R A; Besnard P; Auwerx J
Induction of the fatty acid transport protein 1 and acyl-CoA synthase genes by dimer-selective rexinoids suggests that the peroxisome proliferator-activated receptor-retinoid X receptor heterodimer is their molecular target.
The Journal of biological chemistry 2000;275(17):12612-8.
2000: Pilon A; Briand O; Lestavel S; Copin C; Majd Z; Fruchart J C; Castro G; Clavey V
Apolipoprotein AII enrichment of HDL enhances their affinity for class B type I scavenger receptor but inhibits specific cholesteryl ester uptake.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):1074-81.
2000: Mackness M; Boullier A; Hennuyer N; Mackness B; Hall M; Tailleux A; Duriez P; Delfly B; Durrington P; Fruchart J C; Duverger N; Caillaud J M; Castro G;
Paraoxonase activity is reduced by a pro-atherosclerotic diet in rabbits.
Biochemical and biophysical research communications 2000;269(1):232-6.
2000: Desurmont C; Caillaud J M; Emmanuel F; Benoit P; Fruchart J C; Castro G; Branellec D; Heard J M; Duverger N
Complete atherosclerosis regression after human ApoE gene transfer in ApoE-deficient/nude mice.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):435-42.
2000: Perez-Mendez O; Bruckert E; Franceschini G; Duhal N; Lacroix B; Bonte J P; Sirtori C; Fruchart J C; Turpin G; Luc G
Metabolism of apolipoproteins AI and AII in subjects carrying similar apoAI mutations, apoAI Milano and apoAI Paris.
Atherosclerosis 2000;148(2):317-25.
2000: Lambert M; Boullier A; Hachulla E; Fruchart J C; Teissier E; Hatron P Y; Duriez P
Paraoxonase activity is dramatically decreased in patients positive for anticardiolipin antibodies.
Lupus 2000;9(4):299-300.
1999: Ulloa N; Bustos P; Castro G; Fruchart J; Vera M; Fruchart J C; Calvo C
Characterization of monoclonal antibodies against apolipoproteins A-I and A-II. Epitope expression in LpA-I and LpA-I:A-II particles.
Hybridoma 1999;18(6):513-20.
1999: Ulloa N; Bustos P; Castro G; Fruchart J; Vera M; Fruchart J C; Calvo C
Characterization of monoclonal antibodies against apolipoproteins A-I and A-II. Epitope expression in LpA-I and LpA-I:A-II particles.
Hybridoma 1999;18(6):513-20.
1999: Romon M; Lebel P; Velly C; Marecaux N; Fruchart J C; Dallongeville J
Leptin response to carbohydrate or fat meal and association with subsequent satiety and energy intake.
The American journal of physiology 1999;277(5 Pt 1):E855-61.
1999: Raspé E; Madsen L; Lefebvre A M; Leitersdorf I; Gelman L; Peinado-Onsurbe J; Dallongeville J; Fruchart J C; Berge R; Staels B
Modulation of rat liver apolipoprotein gene expression and serum lipid levels by tetradecylthioacetic acid (TTA) via PPARalpha activation.
Journal of lipid research 1999;40(11):2099-110.
1999: Delerive P; De Bosscher K; Besnard S; Vanden Berghe W; Peters J M; Gonzalez F J; Fruchart J C; Tedgui A; Haegeman G; Staels B
Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1.
The Journal of biological chemistry 1999;274(45):32048-54.
1999: Asset G; Baugé E; Wolff R L; Fruchart J C; Dallongeville J
Pinus pinaster oil affects lipoprotein metabolism in apolipoprotein E-deficient mice.
The Journal of nutrition 1999;129(11):1972-8.
1999: Gervois P; Torra I P; Chinetti G; Grötzinger T; Dubois G; Fruchart J C; Fruchart-Najib J; Leitersdorf E; Staels B
A truncated human peroxisome proliferator-activated receptor alpha splice variant with dominant negative activity.
Molecular endocrinology (Baltimore, Md.) 1999;13(9):1535-49.
1999: Delerive P; Martin-Nizard F; Chinetti G; Trottein F; Fruchart J C; Najib J; Duriez P; Staels B
Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway.
Circulation research 1999;85(5):394-402.
1999: Lefebvre M; Paulweber B; Fajas L; Woods J; McCrary C; Colombel J F; Najib J; Fruchart J C; Datz C; Vidal H; Desreumaux P; Auwerx J
Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells.
The Journal of endocrinology 1999;162(3):331-40.
1999: Le Fur C; Romon M; Lebel P; Devos P; Lancry A; Guédon-Moreau L; Fruchart J C; Dallongeville J
Influence of mental stress and circadian cycle on postprandial lipemia.
The American journal of clinical nutrition 1999;70(2):213-20.
1999: Fajas L; Schoonjans K; Gelman L; Kim J B; Najib J; Martin G; Fruchart J C; Briggs M; Spiegelman B M; Auwerx J
Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism.
Molecular and cellular biology 1999;19(8):5495-503.
1999: Gozzo A; Lesieur D; Duriez P; Fruchart J C; Teissier E
Structure-activity relationships in a series of melatonin analogues with the low-density lipoprotein oxidation model.
Free radical biology & medicine 1999;26(11-12):1538-43.
1999: Schoonjans K; Peinado-Onsurbe J; Fruchart J C; Tailleux A; Fiévet C; Auwerx J
3-Hydroxy-3-methylglutaryl CoA reductase inhibitors reduce serum triglyceride levels through modulation of apolipoprotein C-III and lipoprotein lipase.
FEBS letters 1999;452(3):160-4.
1999: Gottrand F; Beghin L; Duhal N; Lacroix B; Bonte J P; Fruchart J C; Luc G
Moderate red wine consumption in healthy volunteers reduced plasma clearance of apolipoprotein AII.
European journal of clinical investigation 1999;29(5):387-94.
1999: Hennuyer N; Poulain P; Madsen L; Berge R K; Houdebine L M; Branellec D; Fruchart J C; Fiévet C; Duverger N; Staels B
Beneficial effects of fibrates on apolipoprotein A-I metabolism occur independently of any peroxisome proliferative response.
Circulation 1999;99(18):2445-51.
1999: Martin G; Pilon A; Albert C; Vallé M; Hum D W; Fruchart J C; Najib J; Clavey V; Staels B
Comparison of expression and regulation of the high-density lipoprotein receptor SR-BI and the low-density lipoprotein receptor in human adrenocortical carcinoma NCI-H295 cells.
European journal of biochemistry / FEBS 1999;261(2):481-91.
1999: Gervois P; Chopin-Delannoy S; Fadel A; Dubois G; Kosykh V; Fruchart J C; Najïb J; Laudet V; Staels B
Fibrates increase human REV-ERBalpha expression in liver via a novel peroxisome proliferator-activated receptor response element.
Molecular endocrinology (Baltimore, Md.) 1999;13(3):400-9.
1999: Gelman L; Zhou G; Fajas L; Raspé E; Fruchart J C; Auwerx J
p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.
The Journal of biological chemistry 1999;274(12):7681-8.
1999: Asset G; Staels B; Wolff R L; Baugé E; Madj Z; Fruchart J C; Dallongeville J
Effects of Pinus pinaster and Pinus koraiensis seed oil supplementation on lipoprotein metabolism in the rat.
Lipids 1999;34(1):39-44.
1999: Ginzinger D G; Clee S M; Dallongeville J; Lewis M E; Henderson H E; Bauje E; Rogers Q R; Jensen D R; Eckel R H; Dyer R; Innis S; Jones B; Fruchart J C; Hayden M R
Lipid and lipoprotein analysis of cats with lipoprotein lipase deficiency.
European journal of clinical investigation 1999;29(1):17-26.
1999: Brites F D; Cavallero E; de Geitere C; Nicolaïew N; Jacotot B; Rosseneu M; Fruchart J C; Wikinski R L; Castro G R
Abnormal capacity to induce cholesterol efflux and a new LpA-I pre-beta particle in type 2 diabetic patients.
Clinica chimica acta; international journal of clinical chemistry 1999;279(1-2):1-14.
1999: Andersson Y; Majd Z; Lefebvre A M; Martin G; Sechkin A V; Kosykh V; Fruchart J C; Najib J; Staels B
Developmental and pharmacological regulation of apolipoprotein C-II gene expression. Comparison with apo C-I and apo C-III gene regulation.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(1):115-21.
1999: Benoit P; Emmanuel F; Caillaud J M; Bassinet L; Castro G; Gallix P; Fruchart J C; Branellec D; Denèfle P; Duverger N
Somatic gene transfer of human ApoA-I inhibits atherosclerosis progression in mouse models.
Circulation 1999;99(1):105-10.
1999: Fruchart J C; Duriez P; Staels B
[Molecular mechanism of action of the fibrates]
Journal de la Société de biologie 1999;193(1):67-75.
1999: Clavey V; Copin C; Mariotte M C; Baugé E; Chinetti G; Fruchart J; Fruchart J C; Dallongeville J; Staels B
Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 1999;9(3):139-49.
1999: Clavey V; Copin C; Mariotte M C; Baugé E; Chinetti G; Fruchart J; Fruchart J C; Dallongeville J; Staels B
Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 1999;9(3):139-49.
1998: Nion S; Demoor L; Boutillon C; Luchoomun J; Vanloo B; Fievet C; Castro G; Rosseneu M; Fruchart J C; Tartar A; Clavey V
Branched synthetic peptide constructs mimic cellular binding and efflux of apolipoprotein AI in reconstituted high density lipoproteins.
Atherosclerosis 1998;141(2):227-35.
1998: Staels B; Dallongeville J; Auwerx J; Schoonjans K; Leitersdorf E; Fruchart J C
Mechanism of action of fibrates on lipid and lipoprotein metabolism.
Circulation 1998;98(19):2088-93.
1998: Martin-Nizard F; Boullier A; Fruchart J C; Duriez P
Alpha-tocopherol but not beta-tocopherol inhibits thrombin-induced PKC activation and endothelin secretion in endothelial cells.
Journal of cardiovascular risk 1998;5(5-6):339-45.
1998: Walters-Laporte E; Furman C; Fouquet S; Martin-Nizard F; Lestavel S; Gozzo A; Lesieur D; Fruchart J C; Duriez P; Teissier E
A high concentration of melatonin inhibits in vitro LDL peroxidation but not oxidized LDL toxicity toward cultured endothelial cells.
Journal of cardiovascular pharmacology 1998;32(4):582-92.
1998: Vu-Dac N; Chopin-Delannoy S; Gervois P; Bonnelye E; Martin G; Fruchart J C; Laudet V; Staels B
The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein A-I expression by fibrates.
The Journal of biological chemistry 1998;273(40):25713-20.
1998: Chinetti G; Griglio S; Antonucci M; Torra I P; Delerive P; Majd Z; Fruchart J C; Chapman J; Najib J; Staels B
Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages.
The Journal of biological chemistry 1998;273(40):25573-80.
1998: Lefebvre A M; Chen I; Desreumaux P; Najib J; Fruchart J C; Geboes K; Briggs M; Heyman R; Auwerx J
Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice.
Nature medicine 1998;4(9):1053-7.
1998: Dallongeville J; Hecquet B; Lebel P; Edmé J L; Le Fur C; Fruchart J C; Auwerx J; Romon M
Short term response of circulating leptin to feeding and fasting in man: influence of circadian cycle.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1998;22(8):728-33.
1998: Vu-Dac N; Gervois P; Torra I P; Fruchart J C; Kosykh V; Kooistra T; Princen H M; Dallongeville J; Staels B
Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids.
The Journal of clinical investigation 1998;102(3):625-32.
1998: Staels B; Koenig W; Habib A; Merval R; Lebret M; Torra I P; Delerive P; Fadel A; Chinetti G; Fruchart J C; Najib J; Maclouf J; Tedgui A
Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators.
Nature 1998;393(6687):790-3.
1998: Brites F D; Bonavita C D; Cloës M; Yael M J; Fruchart J C; Castro G R; Wikinski R W
VLDL compositional changes and plasma levels of triglycerides and high density lipoprotein.
Clinica chimica acta; international journal of clinical chemistry 1998;269(2):107-24.
1998: Fievet C; Fruchart J C
Measurement of lipoprotein particles.
Methods in molecular biology (Clifton, N.J.) 1998;110():153-66.
1997: Dallongeville J; Baugé E; Lebel P; Fruchart J C
Fat ingestion is associated with increased levels of apoC-III- and apoE-B-containing lipoprotein particles in humans.
European journal of clinical investigation 1997;27(12):1055-60.
1997: Lebuffe G; Boullier A; Tailleux A; Delfly B; Dupuis B; Fruchart J C; Duverger N; Emmanuel F; Denefle P; Vallet B; Duriez P
Endothelial derived vasorelaxation is impaired in human APO A-I transgenic rabbits.
Biochemical and biophysical research communications 1997;241(1):205-11.
1997: Nion S; Briand O; Lestavel S; Torpier G; Nazih F; Delbart C; Fruchart J C; Clavey V
High-density-lipoprotein subfraction 3 interaction with glycosylphosphatidylinositol-anchored proteins.
The Biochemical journal 1997;328 ( Pt 2)():415-23.
1997: Mediene S; Clavey V; Bard J M; Medjaoui I; Fruchart J C; Benhamamouch S
[Serum lipids and lipoproteins in a population from Oran. Comparison with a population from Lille]
Annales de biologie clinique 1997;55(6):577-82.
1997: Lefebvre A M; Peinado-Onsurbe J; Leitersdorf I; Briggs M R; Paterniti J R; Fruchart J C; Fievet C; Auwerx J; Staels B
Regulation of lipoprotein metabolism by thiazolidinediones occurs through a distinct but complementary mechanism relative to fibrates.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(9):1756-64.
1997: Vu-Dac N; Gervois P; Grötzinger T; De Vos P; Schoonjans K; Fruchart J C; Auwerx J; Mariani J; Tedgui A; Staels B
Transcriptional regulation of apolipoprotein A-I gene expression by the nuclear receptor RORalpha.
The Journal of biological chemistry 1997;272(36):22401-4.
1997: Nazih-Sanderson F; Lestavel S; Nion S; Rouy D; Denefle P; Fruchart J C; Clavey V; Delbart C
HDL3 binds to glycosylphosphatidylinositol-anchored proteins to activate signalling pathways.
Biochimica et biophysica acta 1997;1358(1):103-12.
1997: Fajas L; Auboeuf D; Raspé E; Schoonjans K; Lefebvre A M; Saladin R; Najib J; Laville M; Fruchart J C; Deeb S; Vidal-Puig A; Flier J; Briggs M R; Staels B; Vidal H; Auwerx J
The organization, promoter analysis, and expression of the human PPARgamma gene.
The Journal of biological chemistry 1997;272(30):18779-89.
1997: Luc G; Ducimetiere P; Bard J M; Arveiler D; Evans A; Cambien F; Fruchart J C; Fievet C
Distribution of apolipoprotein E between apo B- and non apo B-containing lipoproteins according to apo E phenotype.
Atherosclerosis 1997;131(2):257-62.
1997: Nazih-Sanderson F; Pinchon G; Nion S; Fruchart J C; Delbart C
HDL3-signalling in HepG2 cells involves glycosyl-phosphatidylinositol-anchored proteins.
Biochimica et biophysica acta 1997;1346(1):45-60.
1997: Elkhalil L; Majd Z; Bakir R; Perez-Mendez O; Castro G; Poulain P; Lacroix B; Duhal N; Fruchart J C; Luc G
Fish-eye disease: structural and in vivo metabolic abnormalities of high-density lipoproteins.
Metabolism: clinical and experimental 1997;46(5):474-83.
1997: Romon M; Le Fur C; Lebel P; Edmé J L; Fruchart J C; Dallongeville J
Circadian variation of postprandial lipemia.
The American journal of clinical nutrition 1997;65(4):934-40.
1997: Luc G; Bard J M; Poulain P; Arveiler D; Evans A E; Cambien F; Fruchart J C; Ducimetière P
Relationship between low-density lipoprotein size and apolipoprotein A-I-containing particles: the ECTIM study.
European journal of clinical investigation 1997;27(3):242-7.
1997: Staels B; Schoonjans K; Fruchart J C; Auwerx J
The effects of fibrates and thiazolidinediones on plasma triglyceride metabolism are mediated by distinct peroxisome proliferator activated receptors (PPARs).
Biochimie 1997;79(2-3):95-9.
1997: Castro G; Nihoul L P; Dengremont C; de Geitère C; Delfly B; Tailleux A; Fievet C; Duverger N; Denèfle P; Fruchart J C; Rubin E M
Cholesterol efflux, lecithin-cholesterol acyltransferase activity, and pre-beta particle formation by serum from human apolipoprotein A-I and apolipoprotein A-I/apolipoprotein A-II transgenic mice consistent with the latter being less effective for reverse cholesterol transport.
Biochemistry 1997;36(8):2243-9.
1996: Duverger N; Viglietta C; Berthou L; Emmanuel F; Tailleux A; Parmentier-Nihoul L; Laine B; Fievet C; Castro G; Fruchart J C; Houbebine L M; Denèfie P
Transgenic rabbits expressing human apolipoprotein A-I in the liver.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(12):1424-9.
1996: Bossu J P; Chartier F L; Fruchart J C; Auwerx J; Staels B; Laine B
Two regulatory elements of similar structure and placed in tandem account for the repressive activity of the first intron of the human apolipoprotein A-II gene.
The Biochemical journal 1996;318 ( Pt 2)():547-53.
1996: Duverger N; Kruth H; Emmanuel F; Caillaud J M; Viglietta C; Castro G; Tailleux A; Fievet C; Fruchart J C; Houdebine L M; Denefle P
Inhibition of atherosclerosis development in cholesterol-fed human apolipoprotein A-I-transgenic rabbits.
Circulation 1996;94(4):713-7.
1996: Duverger N; Tremp G; Caillaud J M; Emmanuel F; Castro G; Fruchart J C; Steinmetz A; Denèfle P
Protection against atherogenesis in mice mediated by human apolipoprotein A-IV.
Science (New York, N.Y.) 1996;273(5277):966-8.
1996: Auwerx J; Schoonjans K; Fruchart J C; Staels B
Transcriptional control of triglyceride metabolism: fibrates and fatty acids change the expression of the LPL and apo C-III genes by activating the nuclear receptor PPAR.
Atherosclerosis 1996;124 Suppl():S29-37.
1996: Saladin R; Vu-Dac N; Fruchart J C; Auwerx J; Staels B
Transcriptional induction of rat liver apolipoprotein A-I gene expression by glucocorticoids requires the glucocorticoid receptor and a labile cell-specific protein.
European journal of biochemistry / FEBS 1996;239(2):451-9.
1996: Demoor L; Boutillon C; Fievet C; Vanloo B; Baert J; Rosseneu M; Fruchart J C; Tartar A
Branched synthetic constructs that mimic the physico-chemical properties of apolipoprotein AI in reconstituted high-density lipoproteins.
European journal of biochemistry / FEBS 1996;239(1):74-84.
1996: Chartier F L; Bossu J P; Vu-Dac N; Fruchart J C; Laine B
Involvement of intronic sequences in the transcriptional regulation of apolipoprotein B, E and A-II genes.
Zeitschrift für Gastroenterologie 1996;34 Suppl 3():44-5.
1996: Ziegler O; Méjean L; Igau B; Fruchart J C; Drouin P; Fiévet C
Accessibility of human apolipoprotein B-100 epitopes in insulin-dependent diabetes: relation with the surface lipid environment of atherogenic particles.
Diabetes & metabolism 1996;22(3):179-84.
1996: Magret V; Elkhalil L; Nazih-Sanderson F; Martin F; Bourre J M; Fruchart J C; Delbart C
Entry of polyunsaturated fatty acids into the brain: evidence that high-density lipoprotein-induced methylation of phosphatidylethanolamine and phospholipase A2 are involved.
The Biochemical journal 1996;316 ( Pt 3)():805-11.
1996: Berthou L; Duverger N; Emmanuel F; Langouët S; Auwerx J; Guillouzo A; Fruchart J C; Rubin E; Denèfle P; Staels B; Branellec D
Opposite regulation of human versus mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice.
The Journal of clinical investigation 1996;97(11):2408-16.
1996: Hugue V; Kandoussi M; Parra H J; Dracon M; Fruchart J C; Tacquet A; Cachera C
Alteration of the lipid and apolipoprotein contents of lipoprotein (a) in haemodialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1996;11(5):825-9.
1996: Guerci B; Igau B; Ziegler O; Crea T; Fruchart J C; Drouin P; Fievet C
Intraperitoneal insulin infusion improves the depletion in choline-containing phospholipids of lipoprotein B particles in type I diabetic patients.
Metabolism: clinical and experimental 1996;45(4):430-4.
1996: Teissier E; Walters-Laporte E; Duhem C; Luc G; Fruchart J C; Duriez P
Rapid quantification of alpha-tocopherol in plasma and low- and high-density lipoproteins.
Clinical chemistry 1996;42(3):430-5.
1996: Igau B; Lestavel S; Clavey V; Slomianny C; Drouin P; Bresson R; Fruchart J C; Duriez P; Fiévet C
Apo B-containing lipoprotein particles in poorly controlled insulin-dependent diabetes.
Atherosclerosis 1996;120(1-2):209-19.
1996: Reade V; Mezdour H; Reade R; Kandoussi M; Dracon M; Fruchart J C; Cachera C
Neutral-lipid transfers and cholesteryl ester transfer protein in hemodialyzed patients.
American journal of nephrology 1996;16(5):394-401.
1996: Kandoussi A M; Hugue V; Parra H J; Dracon M; Fruchart J C; Tacquet A; Cachera C
Apolipoprotein AI and apolipoprotein B containing particle analysis in normolipidemic hemodialyzed patients: evidence of free apolipoprotein E.
American journal of nephrology 1996;16(4):287-92.
1995: Aguie G A; Rader D J; Clavey V; Traber M G; Torpier G; Kayden H J; Fruchart J C; Brewer H B; Castro G
Lipoproteins containing apolipoprotein B isolated from patients with abetalipoproteinemia and homozygous hypobetalipoproteinemia: identification and characterization.
Atherosclerosis 1995;118(2):183-91.
1995: Cavallero E; Brites F; Delfly B; Nicolaïew N; Decossin C; De Geitere C; Fruchart J C; Wikinski R; Jacotot B; Castro G
Abnormal reverse cholesterol transport in controlled type II diabetic patients. Studies on fasting and postprandial LpA-I particles.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(12):2130-5.
1995: Romon M; Nuttens M C; Théret N; Delbart C; Lecerf J M; Fruchart J C; Salomez J L
Comparison between fat intake assessed by a 3-day food record and phospholipid fatty acid composition of red blood cells: results from the Monitoring of Cardiovascular Disease-Lille Study.
Metabolism: clinical and experimental 1995;44(9):1139-45.
1995: Vu-Dac N; Schoonjans K; Kosykh V; Dallongeville J; Fruchart J C; Staels B; Auwerx J
Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor.
The Journal of clinical investigation 1995;96(2):741-50.
1995: Vanloo B; Demoor L; Boutillon C; Lins L; Brasseur R; Baert J; Fruchart J C; Tartar A; Rosseneu M
Association of synthetic peptide fragments of human apolipoprotein A-I with phospholipids.
Journal of lipid research 1995;36(8):1686-96.
1995: Brousseau T; Arveiler D; Cambou J P; Evans A E; Luc G; Fruchart J C; Cambien F; Amouyel P
Familial defective apolipoprotein B-100 and myocardial infarction. The ECTIM study. Etude Cas-Témoins de l'Infarctus du Myocarde.
Atherosclerosis 1995;116(2):269-71.
1995: Berthou L; Saladin R; Yaqoob P; Branellec D; Calder P; Fruchart J C; Denèfle P; Auwerx J; Staels B
Regulation of rat liver apolipoprotein A-I, apolipoprotein A-II and acyl-coenzyme A oxidase gene expression by fibrates and dietary fatty acids.
European journal of biochemistry / FEBS 1995;232(1):179-87.
1995: Clavey V; Lestavel-Delattre S; Copin C; Bard J M; Fruchart J C
Modulation of lipoprotein B binding to the LDL receptor by exogenous lipids and apolipoproteins CI, CII, CIII, and E.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(7):963-71.
1995: Lagrost L; Dengremont C; Athias A; de Geitere C; Fruchart J C; Lallemant C; Gambert P; Castro G
Modulation of cholesterol efflux from Fu5AH hepatoma cells by the apolipoprotein content of high density lipoprotein particles. Particles containing various proportions of apolipoproteins A-I and A-II.
The Journal of biological chemistry 1995;270(22):13004-9.
1995: Mehlum A; Staels B; Duverger N; Tailleux A; Castro G; Fievet C; Luc G; Fruchart J C; Olivecrona G; Skretting G
Tissue-specific expression of the human gene for lecithin: cholesterol acyltransferase in transgenic mice alters blood lipids, lipoproteins and lipases towards a less atherogenic profile.
European journal of biochemistry / FEBS 1995;230(2):567-75.
1995: Martin-Nizard F; Sqalli-Houssaini H; Walters-Laporte E; Boullier A; Fruchart J C; Duriez P
Oxidized high-density lipoproteins modulate endothelin secretion by adult bovine aortic endothelial cells.
Journal of cardiovascular risk 1995;2(3):263-7.
1995: Boullier A; Hamon M; Walters-Laporte E; Martin-Nizart F; Mackereel R; Fruchart J C; Bertrand M; Duriez P
Detection of autoantibodies against oxidized low-density lipoproteins and of IgG-bound low density lipoproteins in patients with coronary artery disease.
Clinica chimica acta; international journal of clinical chemistry 1995;238(1):1-10.
1995: Harduin P; Tailleux A; Lestavel S; Clavey V; Fruchart J C; Fievet C
Immunological and functional properties of in vitro oxidized low density lipoprotein.
Journal of lipid research 1995;36(5):919-30.
1995: Brousseau T; Lecerf J M; Luc G; Devulder B; Fruchart J C; Amouyel P
[Detection of the Arg 3500-->Gln mutation of B apolipoprotein. Value in clinical practice]
Presse médicale (Paris, France : 1983) 1995;24(16):769-72.
1995: Tremp G L; Duchange N; Branellec D; Cereghini S; Tailleux A; Berthou L; Fievet C; Touchet N; Schombert B; Fruchart J C
A 700-bp fragment of the human antithrombin III promoter is sufficient to confer high, tissue-specific expression on human apolipoprotein A-II in transgenic mice.
Gene 1995;156(2):199-205.
1995: Fiévet C; Igau B; Bresson R; Drouin P; Fruchart J C
Non-enzymatic glycosylation of apolipoprotein A-I and its functional consequences.
Diabète & métabolisme 1995;21(2):95-8.
1995: Decossin C; Tailleux A; Fruchart J C; Fiévet C
Prevention of in vitro low-density lipoprotein oxidation by an albumin-containing Lp A-I subfraction.
Biochimica et biophysica acta 1995;1255(1):31-8.
1995: Médiène S; Hakem S; Bard J M; Medjaoui I; Benhamamouch S; Lebel P; Fruchart J C; Clavey V
Serum lipoprotein profile in Algerian patients with celiac disease.
Clinica chimica acta; international journal of clinical chemistry 1995;235(2):189-96.
1995: Staels B; Vu-Dac N; Kosykh V A; Saladin R; Fruchart J C; Dallongeville J; Auwerx J
Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates.
The Journal of clinical investigation 1995;95(2):705-12.
1995: Fruchart J C; Duriez P
[The important role of apolipoprotein C-III in lipoprotein metabolism]
Comptes rendus des séances de la Société de biologie et de ses filiales 1995;189(5):889-97.
1995: Duriez P; Fruchart J C
[Lipoparticles and atherosclerosis]
Journées annuelles de diabétologie de l'Hôtel-Dieu 1995;():207-15.
1994: Vu-Dac N; Schoonjans K; Laine B; Fruchart J C; Auwerx J; Staels B
Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element.
The Journal of biological chemistry 1994;269(49):31012-8.
1994: Emmanuel F; Steinmetz A; Rosseneu M; Brasseur R; Gosselet N; Attenot F; Cuiné S; Séguret S; Latta M; Fruchart J C
Identification of specific amphipathic alpha-helical sequence of human apolipoprotein A-IV involved in lecithin:cholesterol acyltransferase activation.
The Journal of biological chemistry 1994;269(47):29883-90.
1994: Guerci B; Igau B; Ziegler O; Crea T; Fruchart J C; Drouin P; Fievet C
Lack of relationship between Lp(a) particle levels and albumin excretion rate in type 1 diabetic patients.
Diabète & métabolisme 1994;20(6):526-31.
1994: Berthou L; Staels B; Saldicco I; Berthelot K; Casey J; Fruchart J C; Denèfle P; Branellec D
Opposite in vitro and in vivo regulation of hepatic apolipoprotein A-I gene expression by retinoic acid. Absence of effects on apolipoprotein A-II gene expression.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(10):1657-64.
1994: Campos E; Fiévet P; Cacès E; Fruchart J C; Fiévet C
A screening method for abnormally high lipoprotein(a) concentrations by agarose lipoprotein electrophoresis.
Clinica chimica acta; international journal of clinical chemistry 1994;230(1):43-50.
1994: Chartier F L; Bossu J P; Laudet V; Fruchart J C; Laine B
Cloning and sequencing of cDNAs encoding the human hepatocyte nuclear factor 4 indicate the presence of two isoforms in human liver.
Gene 1994;147(2):269-72.
1994: Nazih H; Nazih-Sanderson F; Magret V; Caron B; Goudemand J; Fruchart J C; Delbart C
Protein kinase C-dependent desensitization of HDL3-activated phospholipase C in human platelets.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(8):1321-6.
1994: Bossu J P; Chartier F L; Vu-Dac N; Fruchart J C; Laine B
Transcription of the human apolipoprotein A-II is down-regulated by the first intron of its gene.
Biochemical and biophysical research communications 1994;202(2):822-9.
1994: Lestavel S; Fruchart J C
Lipoprotein receptors.
Cellular and molecular biology (Noisy-le-Grand, France) 1994;40(4):461-81.
1994: Luchoomun J; Theret N; Clavey V; Duchateau P; Rosseneu M; Brasseur R; Denefle P; Fruchart J C; Castro G R
Structural domain of apolipoprotein A-I involved in its interaction with cells.
Biochimica et biophysica acta 1994;1212(3):319-26.
1994: Rosseneu M; Fruchart J C; Bard J M; Nicaud V; Vinaimont N; Cambien F; De Backer G
Plasma apolipoprotein concentrations in young adults with a parental history of premature coronary heart disease and in control subjects. The EARS Study. European Atherosclerosis Research Study.
Circulation 1994;89(5):1967-73.
1994: Lestavel-Delattre S; Benhamamouch S; Agnani G; Luc G; Bard J M; Brousseau T; Billardon C; Kusnierz J P; De Gennes J L; Fruchart J C
Evidence of non-deficient low-density lipoprotein receptor patients in a pool of subjects with clinical familial hypercholesterolemia profile.
Metabolism: clinical and experimental 1994;43(4):397-402.
1994: Mezdour H; Kora I; Parra H J; Tartar A; Marcel Y L; Fruchart J C
Two-site enzyme immunoassay of cholesteryl ester transfer protein with monoclonal and oligoclonal antibodies.
Clinical chemistry 1994;40(4):593-7.
1994: Duverger N; Ghalim N; Theret N; Fruchart J C; Castro G
Lipoproteins containing apolipoprotein A-IV: composition and relation to cholesterol esterification.
Biochimica et biophysica acta 1994;1211(1):23-8.
1994: Sqalli-Houssaini H; Pierlot C; Kusnierz J P; Parmentier B; Martin-Nizard F; Lestavel-Delattre S; Tartar A; Fruchart J C; Sergheraert C; Duriez P
Preparation of anti-HIV-low-density lipoprotein complexes for delivery of anti-HIV drugs via the low-density lipoprotein pathways.
Biotechnology therapeutics 1994;5(1-2):69-85.
1993: Reade V; Tailleux A; Reade R; Harduin P; Cachera C; Tacquet A; Fruchart J C; Fievet C
Expression of apolipoprotein B epitopes in low density lipoproteins of hemodialyzed patients.
Kidney international 1993;44(6):1360-5.
1993: Duverger N; Rader D; Duchateau P; Fruchart J C; Castro G; Brewer H B
Biochemical characterization of the three major subclasses of lipoprotein A-I preparatively isolated from human plasma.
Biochemistry 1993;32(46):12372-9.
1993: Amouyel P; Isorez D; Bard J M; Goldman M; Lebel P; Zylberberg G; Fruchart J C
Parental history of early myocardial infarction is associated with decreased levels of lipoparticle AI in adolescents.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(11):1640-4.
1993: Duchateau P; Rader D; Duverger N; Theret N; De Geitere C; Brewer H B; Fruchart J C; Castro G R
Tangier disease: isolation and characterization of LpA-I, LpA-II, LpA-I: A-II and LpA-IV particles from plasma.
Biochimica et biophysica acta 1993;1182(1):30-6.
1993: Bard J M; Fruchart J C
Triglyceride-rich particles, high-density lipoprotein and their pharmacological modulation.
Biochemical Society transactions 1993;21 ( Pt 3)(3):647-9.
1993: Brousseau T; Clavey V; Bard J M; Fruchart J C
Sequential ultracentrifugation micromethod for separation of serum lipoproteins and assays of lipids, apolipoproteins, and lipoprotein particles.
Clinical chemistry 1993;39(6):960-4.
1993: Pieters M N; Castro G R; Schouten D; Duchateau P; Fruchart J C; Van Berkel T J
Cholesterol esters selectively delivered in vivo by high-density-lipoprotein subclass LpA-I to rat liver are processed faster into bile acids than are LpA-I/A-II-derived cholesterol esters.
The Biochemical journal 1993;292 ( Pt 3)():819-23.
1993: Theret N; Bard J M; Nuttens M C; Lecerf J M; Delbart C; Romon M; Salomez J L; Fruchart J C
The relationship between the phospholipid fatty acid composition of red blood cells, plasma lipids, and apolipoproteins.
Metabolism: clinical and experimental 1993;42(5):562-8.
1993: Tailleux A; Torpier G; Caron B; Fruchart J C; Fievet C
Immunological properties of apoB-containing lipoprotein particles in human atherosclerotic arteries.
Journal of lipid research 1993;34(5):719-28.
1993: Bard J M; Fruchart J C
HDL particle measurements: impact for diagnosis and therapy.
Clinical biochemistry 1993;26(2):65-8.
1993: Harduin P; Tailleux A; Fruchart J C; Fievet C
Modulation of the expression of human LDL-Apo B-100 epitopes by lipids and apolipoproteins.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(4):529-35.
1993: von Eckardstein A; Castro G; Wybranska I; Theret N; Duchateau P; Duverger N; Fruchart J C; Ailhaud G; Assmann G
Interaction of reconstituted high density lipoprotein discs containing human apolipoprotein A-I (ApoA-I) variants with murine adipocytes and macrophages. Evidence for reduced cholesterol efflux promotion by apoA-I(Pro165-->Arg).
The Journal of biological chemistry 1993;268(4):2616-22.
1993: Duverger N; Ghalim N; Ailhaud G; Steinmetz A; Fruchart J C; Castro G
Characterization of apoA-IV-containing lipoprotein particles isolated from human plasma and interstitial fluid.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(1):126-32.
1992: Fievet C; Theret N; Shojaee N; Duchateau P; Castro G; Ailhaud G; Drouin P; Fruchart J C
Apolipoprotein A-I-containing particles and reverse cholesterol transport in IDDM.
Diabetes 1992;41 Suppl 2():81-5.
1992: Romon M; Nuttens M C; Fievet C; Pot P; Bard J M; Furon D; Fruchart J C
Increased triglyceride levels in shift workers.
The American journal of medicine 1992;93(3):259-62.
1992: Nazih H; Devred D; Martin-Nizard F; Clavey V; Fruchart J C; Delbart C
Pertussis toxin sensitive G-protein coupling of HDL receptor to phospholipase C in human platelets.
Thrombosis research 1992;67(5):559-67.
1992: Kandoussi A; Cachera C; Pagniez D; Dracon M; Fruchart J C; Tacquet A
Plasma level of lipoprotein Lp(a) is high in predialysis or hemodialysis, but not in CAPD.
Kidney international 1992;42(2):424-5.
1992: Bard J M; Delattre-Lestavel S; Clavey V; Pont P; Derudas B; Parra H J; Fruchart J C
Isolation and characterization of two sub-species of Lp(a), one containing apo E and one free of apo E.
Biochimica et biophysica acta 1992;1127(2):124-30.
1992: Fruchart J C; Ailhaud G
Apolipoprotein A-containing lipoprotein particles: physiological role, quantification, and clinical significance.
Clinical chemistry 1992;38(6):793-7.
1992: Dehouck M P; Jolliet-Riant P; Brée F; Fruchart J C; Cecchelli R; Tillement J P
Drug transfer across the blood-brain barrier: correlation between in vitro and in vivo models.
Journal of neurochemistry 1992;58(5):1790-7.
1992: Adamantidis M M; Moreau-Guedon L; Martin-Nizard F; Sqalli-Houssaini H; Duriez P; Fruchart J C; Dupuis B
Oxidized low density lipoproteins exert arrhythmogenic effects in rabbit Purkinje fibers.
Biochemical and biophysical research communications 1992;182(2):548-54.
1992: Kandoussi A; Cachera C; Reade R; Pagniez D; Fruchart J C; Tacquet A
Apo AIV in plasma and dialysate fluid of CAPD patients: comparison with other apolipoproteins.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1992;7(10):1026-9.
1991: Luc G; Bard J M; Lussier-Cacan S; Bouthillier D; Parra H J; Fruchart J C; Davignon J
High-density lipoprotein particles in octogenarians.
Metabolism: clinical and experimental 1991;40(12):1238-43.
1991: Martin-Nizard F; Houssaini H S; Lestavel-Delattre S; Duriez P; Fruchart J C
Modified low density lipoproteins activate human macrophages to secrete immunoreactive endothelin.
FEBS letters 1991;293(1-2):127-30.
1991: Rader D J; Castro G; Zech L A; Fruchart J C; Brewer H B
In vivo metabolism of apolipoprotein A-I on high density lipoprotein particles LpA-I and LpA-I,A-II.
Journal of lipid research 1991;32(11):1849-59.
1991: Duverger N; Murry-Brelier A; Latta M; Reboul S; Castro G; Mayaux J F; Fruchart J C; Taylor J M; Steinmetz A; Denèfle P
Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli.
European journal of biochemistry / FEBS 1991;201(2):373-83.
1991: Parra H J; Martin F; Monard F; Ngangoué N; Copin N; Bard J M; Qafli M; Vu Dac N; Duriez P; Fruchart J C
Apolipoprotein B polymorphism and altered apolipoprotein B concentrations in Congolese blacks.
Clinical genetics 1991;40(4):263-70.
1991: Agnani G; Bard J M; Candelier L; Delattre S; Fruchart J C; Clavey V
Interaction of LpB, LpB:E, LpB:C-III, and LpB:C-III:E lipoproteins with the low density lipoprotein receptor of HeLa cells.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(4):1021-9.
1991: Barkia A; Puchois P; Ghalim N; Torpier G; Barbaras R; Ailhaud G; Fruchart J C
Differential role of apolipoprotein AI-containing particles in cholesterol efflux from adipose cells.
Atherosclerosis 1991;87(2-3):135-46.
1991: Davignon J; Dallongeville J; Roederer G; Roy M; Fruchart J C; Kessling A M; Bouthillier D; Lussier-Cacan S
A phenocopy of type III dysbetalipoproteinemia occurring in a candidate family for a putative apo E receptor defect.
Annals of medicine 1991;23(2):161-7.
1991: Bard J M; Candelier L; Agnani G; Clavey V; Torpier G; Steinmetz A; Fruchart J C
Isolation and characterization of human Lp-B lipoprotein containing apolipoprotein B as the sole apolipoprotein.
Biochimica et biophysica acta 1991;1082(2):170-6.
1991: Moussavi Z; Depreux P; Lesieur D; Cotelle N; Sauzieres J; Plancke M O; Fruchart J C
Pharmacomodulation of 7-(2-methylene-butyryl)-2,3-dihydrobenzoxazin-[1,4]-3-one structure and normolipemic activity.
Farmaco (Società chimica italiana : 1989) 1991;46(2):339-55.
1991: Luc G; Fruchart J C
Oxidation of lipoproteins and atherosclerosis.
The American journal of clinical nutrition 1991;53(1 Suppl):206S-209S.
1991: Kandoussi A; Cachera C; Parsy D; Bard J M; Fruchart J C
Quantitative determination of different apolipoprotein B containing lipoproteins by an enzyme linked immunosorbent assay: apo B with apo C-III and apo B with apo E.
Journal of immunoassay 1991;12(3):305-23.
1991: Duverger N; Ghalim N; Theret N; Duchateau P; Aguie G; Ailhaud G; Castro G; Fruchart J C
Lipoprotein A-I containing particles.
Advances in experimental medicine and biology 1991;285():93-9.
1991: Barbaras R; Puchois P; Pradines-Figuères A; Steinmetz A; Clavey V; Ghalim N; Fruchart J C; Ailhaud G
[Liaison of apolipoprotein A with adipose cells: characteristics of the receptor sites and their role in the efflux of cholesterol]
Journées annuelles de diabétologie de l'Hôtel-Dieu 1991;():39-43.
1991: Harduin P; Fiévet C; Fruchart J C
[Conformational changes in lipoproteins containing apo B: significance of monoclonal antibodies]
Journées annuelles de diabétologie de l'Hôtel-Dieu 1991;():25-34.
1991: Clavey V; Agnani G; Bard J M; Lestavel-Delattre S; Fruchart J C
[Interaction between LDL receptor and lipoproteins containing apo B]
Annales d'endocrinologie 1991;52(6):459-63.
1991: Barbaras R; Puchois P; Pradines-Figuères A; Steinmetz A; Clavey V; Ghalim N; Fruchart J C; Ailhaud G
Binding of apolipoproteins A to adipose cells: role of receptor sites in cholesterol efflux and purification of binding protein(s).
Advances in experimental medicine and biology 1991;285():85-92.
1990: Gairin D; Monard F; Cachera C; Bard J M; Amouyel P; Duriez P; Tacquet A; Fruchart J C
Lipoprotein particles in homozygous familial hypercholesterolemic patients treated with portacaval shunt and LDL apheresis.
Clinica chimica acta; international journal of clinical chemistry 1990;193(3):165-79.
1990: Theret N; Delbart C; Aguie G; Fruchart J C; Vassaux G; Ailhaud G
Cholesterol efflux from adipose cells is coupled to diacylglycerol production and protein kinase C activation.
Biochemical and biophysical research communications 1990;173(3):1361-8.
1990: Nazih H; Devred D; Martin-Nizard F; Fruchart J C; Delbart C
Phosphatidylcholine breakdown in HDL3 stimulated platelets.
Thrombosis research 1990;59(6):913-20.
1990: Barbaras R; Puchois P; Fruchart J C; Pradines-Figueres A; Ailhaud G
Purification of an apolipoprotein A binding protein from mouse adipose cells.
The Biochemical journal 1990;269(3):767-73.
1990: Parra H J; Mezdour H; Ghalim N; Bard J M; Fruchart J C
Differential electroimmunoassay of human LpA-I lipoprotein particles on ready-to-use plates.
Clinical chemistry 1990;36(8 Pt 1):1431-5.
1990: Puchois P; Ghalim N; Zylberberg G; Fievet P; Demarquilly C; Fruchart J C
Effect of alcohol intake on human apolipoprotein A-I-containing lipoprotein subfractions.
Archives of internal medicine 1990;150(8):1638-41.
1990: Dehouck M P; Méresse S; Delorme P; Fruchart J C; Cecchelli R
An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro.
Journal of neurochemistry 1990;54(5):1798-801.
1990: Steinmetz A; Barbaras R; Ghalim N; Clavey V; Fruchart J C; Ailhaud G
Human apolipoprotein A-IV binds to apolipoprotein A-I/A-II receptor sites and promotes cholesterol efflux from adipose cells.
The Journal of biological chemistry 1990;265(14):7859-63.
1990: Alessi M C; Parra H J; Joly P; Vu-Dac N; Bard J M; Fruchart J C; Juhan-Vague I
The increased plasma Lp(a): B lipoprotein particle concentration in angina pectoris is not associated with hypofibrinolysis.
Clinica chimica acta; international journal of clinical chemistry 1990;188(2):119-27.
1990: Fievet C; Ziegler O; Parra H J; Mejean L; Fruchart J C; Drouin P
Depletion in choline containing phospholipids of LpB particles in adequately controlled type I insulin-dependent diabetes mellitus.
Diabète & métabolisme 1990;16(2):64-9.
1990: Bard J M; Parra H J; Douste-Blazy P; Fruchart J C
Effect of pravastatin, an HMG CoA reductase inhibitor, and cholestyramine, a bile acid sequestrant, on lipoprotein particles defined by their apolipoprotein composition.
Metabolism: clinical and experimental 1990;39(3):269-73.
1990: Kandoussi A; Cachera C; Reade R; Tacquet A; Fruchart J C
[Application of the immunoenzyme technic in double determination of antibodies for the study of hyperlipoproteinemia]
Annales de biologie clinique 1990;48(6):365-8.
1990: Saile R; Fruchart J C
[Serum amyloid A apolipoprotein (apo SAA). Implications in inflammation and in lipoprotein modifications]
Annales de biologie clinique 1990;48(2):77-85.
1990: Mezdour H; Parra H J; Aguie-Aguie G; Fruchart J C
[Lipoprotein (a). An additional marker of atherosclerosis]
Annales de biologie clinique 1990;48(3):139-53.
1990: Beucler I; Caces E; Camare R; Dachet C; Fruchart J C; Gambert P; Girault A; Leglise D; Legrand A; Mainard F
[Use of 6 serum pools in standardization of the determination of apolipoproteins AI and B in the human serum]
Annales de biologie clinique 1990;48(7):443-7.
1990: Cachera C; Kandoussi A; Equagoo K; Fruchart J C; Tacquet A
Evaluation of apolipoprotein A-I containing particles in chronic renal failure patients undergoing hemodialysis.
American journal of nephrology 1990;10(2):171-2.
1989: Theret N; Bourre J M; Fruchart J C; Delbart C
Intramyelinic conversion of cerebrosides into acylgalactosylceramides.
Neurochemical research 1989;14(12):1235-40.
1989: Agnani G; Delpierre C; Benhamamouch S; Torpier G; Cachera C; Koffigan M; Tartar A; Fruchart J C; Clavey V
Antipeptide antibody against the human low-density-lipoprotein receptor. Characterization and cross-reactivity with bovine lymphocytes.
The Biochemical journal 1989;263(3):753-60.
1989: Méresse S; Dehouck M P; Delorme P; Bensaïd M; Tauber J P; Delbart C; Fruchart J C; Cecchelli R
Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long-term culture.
Journal of neurochemistry 1989;53(5):1363-71.
1989: Steinmetz A; Hocke G; Saïle R; Puchois P; Fruchart J C
Influence of serum amyloid A on cholesterol esterification in human plasma.
Biochimica et biophysica acta 1989;1006(2):173-8.
1989: Milne R; Théolis R; Maurice R; Pease R J; Weech P K; Rassart E; Fruchart J C; Scott J; Marcel Y L
The use of monoclonal antibodies to localize the low density lipoprotein receptor-binding domain of apolipoprotein B.
The Journal of biological chemistry 1989;264(33):19754-60.
1989: Martin-Nizard F; Meresse S; Cecchelli R; Fruchart J C; Delbart C
Interactions of high-density lipoprotein 3 with brain capillary endothelial cells.
Biochimica et biophysica acta 1989;1005(3):201-8.
1989: Leroy A; Vu-Dac N; Theret N; Pio F; Fruchart J C
Expression, location and cross-reactivity of two antigenic sites on the amino terminal region of rabbit and human apolipoprotein A-I.
Atherosclerosis 1989;79(1):9-19.
1989: Saïle R; Hocke G; Tartar A; Fruchart J C; Steinmetz A
Antipeptide antibodies discriminate between different SAA proteins in human plasma.
Biochimica et biophysica acta 1989;992(3):407-8.
1989: Vu Dac N; Mezdour H; Parra H J; Luc G; Luyeye I; Fruchart J C
A selective bi-site immunoenzymatic procedure for human Lp[a] lipoprotein quantification using monoclonal antibodies against apo[a] and apoB.
Journal of lipid research 1989;30(9):1437-43.
1989: Méresse S; Delbart C; Fruchart J C; Cecchelli R
Low-density lipoprotein receptor on endothelium of brain capillaries.
Journal of neurochemistry 1989;53(2):340-5.
1989: Fievet C; Durieux C; Milne R; Delaunay T; Agnani G; Bazin H; Marcel Y; Fruchart J C
Rat monoclonal antibodies to human apolipoprotein B: advantages and applications.
Journal of lipid research 1989;30(7):1015-24.
1989: Steinmetz A; Saïle R; Sefraoui M; Parra H J; Fruchart J C
Confusion of apolipoprotein E phenotyping by serum amyloid A.
Clinical chemistry 1989;35(4):671-2.
1989: Fruchart J C; Sauzières J; Plancke M O; Luc G; Clavey V
[Modified lipoproteins and atherogenesis]
Presse médicale (Paris, France : 1983) 1989;18(14):701-2.
1989: Moussavi Z; Plancke M O; Olivier P; Lesieur D; Fruchart J C; Sauzieres J
Lipid lowering actions of 7-(2-methylene butyryl)-(2H)-1,4-benzoxazin-3-(4H)-one derivatives in mice, rats and Syrian hamsters.
Clinica chimica acta; international journal of clinical chemistry 1989;180(1):35-44.
1989: Benhamamouch S; Kuznierz J P; Agnani G; Marzin D; Lecerf J M; Fruchart J C; Clavey V
Determination of the LDL receptor binding capacity of human lymphocytes by immunocytofluorimetric assay.
Biochimica et biophysica acta 1989;1002(1):45-53.
1989: James R W; Martin B; Pometta D; Fruchart J C; Duriez P; Puchois P; Farriaux J P; Tacquet A; Demant T; Clegg R J
Apolipoprotein B metabolism in homozygous familial hypercholesterolemia.
Journal of lipid research 1989;30(2):159-69.
1989: Steinmetz A; Clavey V; Vu-Dac N; Kaffarnik H; Fruchart J C
Purification of human apolipoprotein A-IV by fast protein liquid chromatography.
Journal of chromatography 1989;487(1):154-60.
1989: Leroy A; Olivier P; Vu-Dac N; Fruchart J C
Characterization of two monoclonal antibodies to human apolipoprotein A-I that also bind to rabbit apolipoprotein A-I. Application to ELISA evaluation of rabbit serum apo A-I.
Clinica chimica acta; international journal of clinical chemistry 1989;179(1):85-95.
1989: Bard J M; Luc G; Douste-Blazy P; Drouin P; Ziegler O; Jacotot B; Dachet C; De Gennes J L; Fruchart J C
Effect of simvastatin on plasma lipids, apolipoproteins and lipoprotein particles in patients with primary hypercholesterolaemia.
European journal of clinical pharmacology 1989;37(6):545-50.
1989: Reade R; Equagoo V; Cachera C; Duriez P; Dracon M; Bard J M; Fievet C; Bertrand M; Tacquet A; Fruchart J C
Apolipoprotein B immunochemical heterogeneity in dialysed patients with chronic renal failure and patients with coronary artery stenosis.
American journal of nephrology 1989;9(2):110-4.
1988: Lecerf J M; Bard J M; Leclerc V; Douste-Blazy P; Devulder B; Harvengt C; Fruchart J C
[Type IIa dyslipoproteinemia. Effects of simvastatin and bezafibrate on atherogenic and non-atherogenic lipoprotein particles]
Presse médicale (Paris, France : 1983) 1988;17(45):2400.
1988: Olivier P; Plancke M O; Theret N; Marzin D; Clavey V; Fruchart J C
Effects of fenofibrate on lipoprotein metabolism and fatty acid distribution in Zucker rats.
Atherosclerosis 1988;74(1-2):15-21.
1988: Pruvot I; Fievet C; Durieux C; Vu Dac N; Fruchart J C
Electroimmuno- and immunonephelometric assays of apolipoprotein A-I by using a mixture of monoclonal antibodies.
Clinical chemistry 1988;34(10):2048-52.
1988: Saïle R; Delpierre C; Puchois P; Hocke G; Cachera C; Gesquiere J C; Steinmetz A; Tartar A; Fruchart J C
Enzyme-linked immunosorbent assay for serum amyloid A apolipoprotein with use of specific antibodies against synthetic peptides.
Clinical chemistry 1988;34(9):1767-71.
1988: Plancke M O; Olivier P; Clavey V; Marzin D; Fruchart J C
Aspects of cholesterol metabolism in normal and hypercholesterolemic Syrian hamsters. Influence of fenofibrate.
Methods and findings in experimental and clinical pharmacology 1988;10(9):575-9.
1988: Luyeye I; Fievet C; Dupont J C; Durieux C; Slimane N; Lecocq J F; Demarquilly C; Fruchart J C
Human apolipoprotein B. Evidence for its immunochemical heterogeneity using monoclonal antibodies and an immunoenzymometric assay.
Clinical biochemistry 1988;21(4):255-61.
1988: Delpierre C; Fievet C; Equagoo V; Mezdour H; Cachera C; Gesquière J C; Tartar A; Fruchart J C
Antibodies of predetermined specificity to apolipoprotein C-II elicited with a synthetic peptide. Characterization and use for immunoassays.
Journal of immunological methods 1988;109(1):61-8.
1988: Theret N; Boulenguer P; Fournet B; Fruchart J C; Bourre J M; Delbart C
Acylgalactosylceramides in developing dysmyelinating mutant mice.
Journal of neurochemistry 1988;50(3):883-8.
1988: Olivier P; Plancke M O; Marzin D; Clavey V; Sauzieres J; Fruchart J C
Effects of fenofibrate, gemfibrozil and nicotinic acid on plasma lipoprotein levels in normal and hyperlipidemic mice. A proposed model for drug screening.
Atherosclerosis 1988;70(1-2):107-14.
1988: Dunning A M; Duriez P; Vu Dac N; Fruchart J C; Humphries S E
Association between epitopes detected by monoclonal antibody BIP-45 and the XbaI polymorphism of apolipoprotein B.
Clinical genetics 1988;33(3):181-8.
1988: Pio F; De Loof H; Vu Dac N; Clavey V; Fruchart J C; Rosseneu M
Immunochemical characterization of two antigenic sites on human apolipoprotein A-I; localization and lipid modulation of these epitopes.
Biochimica et biophysica acta 1988;959(2):160-8.
1988: Barkia A; Martin C; Puchois P; Gesquiere J C; Cachera C; Tartar A; Fruchart J C
Enzyme-linked immunosorbent assay for human proapolipoprotein A-I using specific antibodies against synthetic peptide.
Journal of lipid research 1988;29(1):77-84.
1988: Gries A; Fievet C; Marcovina S; Nimpf J; Wurm H; Mezdour H; Fruchart J C; Kostner G M
Interaction of LDL, Lp[a], and reduced Lp[a] with monoclonal antibodies against apoB.
Journal of lipid research 1988;29(1):1-8.
1988: Fruchart J C; Bard J M; Fievet C; Kandoussi A; Slimane M; Douste-Blazy P
Effect of fenofibrate on apolipoprotein B containing lipoprotein particles.
Progress in clinical and biological research 1988;255():305-10.
1988: Leroy A; Vu-dac N; Koffigan M; Clavey V; Fruchart J C
Characterization of a monoclonal antibody that binds to apolipoprotein E and to lipoprotein of human plasma containing apo E. Applications to ELISA quantification of plasma apo E.
Journal of immunoassay 1988;9(3-4):309-34.
1988: Parra H J; Cachera C; Equagoo K; Dracon M; Fruchart J C; Tacquet A
Quantitative abnormalities of lipoprotein particles in chronic hemodialysis patients.
Advances in experimental medicine and biology 1988;243():283-7.
1988: Barkia A; Barbaras R; Ghalim N; Puchois P; Ailhaud G; Fruchart J C
Effect of different APO A-I containing lipoprotein particles on reverse cholesterol transport in fat cells.
Hormone and metabolic research. Supplement series 1988;19():10-2.
1988: Parsy D; Dracon M; Cachera C; Parra H J; Vanhoutte G; Tacquet A; Fruchart J C
Lipoprotein abnormalities in chronic haemodialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1988;3(1):51-6.
1988: Barbaras R; Puchois P; Grimaldi P; Barkia A; Fruchart J C; Ailhaud G
HDL receptor and reverse cholesterol transport in adipose cells.
Advances in experimental medicine and biology 1988;243():271-7.
1988: Broutin H; Puchois P; Ailhaud G; Barbaras R; Torpier G; Fruchart J C
[Receptors and molecular heterogeneity of lipoprotein particles containing apolipoprotein A-I]
Annales de biologie clinique 1988;46(1):16-23.
1988: Fruchart J C; Puchois P; Fievet C; Ghalim N; Luyeye I; Parra H
Polyclonal and monoclonal antibody mapping of lipoprotein particles. Clinical applications.
Progress in clinical and biological research 1988;255():175-82.
1987: Betard C; Vu-Dac N; Mezdour H; Nestruck A C; Leroy A; Fruchart J C
Standardization of an enzymometric assay for apolipoprotein A-I by using mixtures of monoclonal antibodies).
Journal of clinical chemistry and clinical biochemistry. Zeitschrift für klinische Chemie und klinische Biochemie 1987;25(12):893-9.
1987: Barbaras R; Puchois P; Grimaldi P; Barkia A; Fruchart J C; Ailhaud G
Relationship in adipose cells between the presence of receptor sites for high density lipoproteins and the promotion of reverse cholesterol transport.
Biochemical and biophysical research communications 1987;149(2):545-54.
1987: Fruchart J C; Davignon J; Bard J M; Grothe A M; Richard A; Fievet C
Effect of fenofibrate treatment on type III hyperlipoproteinemia.
The American journal of medicine 1987;83(5B):71-4.
1987: Bonneterre J; Ghalim N; Nguyen M; Puchois P; Demaille A; Demarquilly C; Fruchart J C
Variations in lipoproteins during aminoglutethimide therapy.
Breast cancer research and treatment 1987;10(2):197-200.
1987: Parra H J; Puchois P; Demarquilly C; Fruchart J C
[Multivariate analysis of biological markers of excessive consumption of alcohol. Value of lipoprotein parameters]
Pathologie-biologie 1987;35(9):1230-4.
1987: Puchois P; Kandoussi A; Fievet P; Fourrier J L; Bertrand M; Koren E; Fruchart J C
Apolipoprotein A-I containing lipoproteins in coronary artery disease.
Atherosclerosis 1987;68(1-2):35-40.
1987: Parra H J; Luyéyé I; Bouramoué C; Demarquilly C; Fruchart J C
Black-white differences in serum Lp(a) lipoprotein levels.
Clinica chimica acta; international journal of clinical chemistry 1987;168(1):27-31.
1987: Duriez P; Butler R; Tikkanen M J; Steinmetz J; Vu Dac N; Butler-Brunner E; Luyeye I; Bard J M; Puchois P; Fruchart J C
A monoclonal antibody (BIP 45) detects Ag(c,g) polymorphism of human apolipoprotein B.
Journal of immunological methods 1987;102(2):205-12.
1987: Martin-Nizard F; Richard B; Torpier G; Nouvelot A; Fruchart J C; Duthilleul P; Delbart C
Analysis of phospholipid transfer during HDL binding to platelets using a fluorescent analog of phosphatidylcholine.
Thrombosis research 1987;46(6):811-25.
1987: Parra H J; Mezdour H; Cachera C; Dracon M; Tacquet A; Fruchart J C
Lp(a) lipoprotein in patients with chronic renal failure treated by hemodialysis.
Clinical chemistry 1987;33(5):721.
1987: Koffigan M; Kora I; Clavey V; Bard J M; Chapman J; Fruchart J C
Quantification of human apolipoprotein E in plasma and lipoprotein subfractions by a non-competitive enzyme immunoassay.
Clinica chimica acta; international journal of clinical chemistry 1987;163(3):245-56.
1987: Mezdour H; Clavey V; Kora I; Koffigan M; Barkia A; Fruchart J C
Anion-exchange fast protein liquid chromatographic characterization and purification of apolipoproteins A-I, A-II, C-I, C-II, C-III0, C-III1, C-III2 and E from human plasma.
Journal of chromatography 1987;414(1):35-45.
1987: Theret N; Boulenguer P; Wieruszeski J M; Fournet B; Fruchart J C; Bourre J M; Delbart C
Structure determination of the polymorphism of acylgalactosylceramide in rat brain by gas chromatography/mass spectrometry and proton magnetic resonance.
Biochimica et biophysica acta 1987;917(1):194-202.
1987: Koren E; Puchois P; Alaupovic P; Fesmire J; Kandoussi A; Fruchart J C
Quantification of two different types of apolipoprotein A-I containing lipoprotein particles in plasma by enzyme-linked differential-antibody immunosorbent assay.
Clinical chemistry 1987;33(1):38-43.
1987: Barbaras R; Puchois P; Fruchart J C; Ailhaud G
Cholesterol efflux from cultured adipose cells is mediated by LpAI particles but not by LpAI:AII particles.
Biochemical and biophysical research communications 1987;142(1):63-9.
1987: Delpierre C; Martin C; Gesquiere J C; Tartar A; Cachera C; Puchois P; Fievet C; Fruchart J C
Chemical approach to synthetic immunogens in clinical chemistry.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1987;14(4):281-8.
1987: Fruchart J C; Koffigan M; Fievet C; Cachera C; Dac N V; Gesquière J C; Puchois P
Molecular analysis of lipoproteins: clinical applications.
Advances in experimental medicine and biology 1987;210():225-31.
1986: Fievet C; Dedieu A; Kandoussi A; Luyeye I; Fruchart J C
Quantitation of human serum apolipoprotein B by enzyme immunoassay in excess antigen.
Clinica chimica acta; international journal of clinical chemistry 1986;159(3):269-78.
1986: Puchois P; Kandoussi A; Duriez P; Fruchart J C; McConathy W J; Koren E
Quantitative determination of human plasma apolipoprotein A-II by a non competitive enzyme-linked immunosorbent assay.
Journal of immunoassay 1986;7(4):285-307.
1985: Parsy D; Clavey V; Fievet C; Kora I; Duriez P; Fruchart J C
Quantification of apolipoprotein C-III in serum by a noncompetitive immunoenzymometric assay.
Clinical chemistry 1985;31(10):1632-5.
1985: Fruchart J C; Luyeye I; Parra H; Slimane M; Fievet C
[Atherogenic lipoproteins and their immunological detection]
Bulletin de l'Académie nationale de médecine 1985;169(6):719-28.
1985: Gesquière J C; Delpierre C C; Tartar A L; Cachera C; Equagoo K V; Fruchart J C
Synthetic peptides as alternative antigens in the production of antibodies against human apolipoproteins.
Clinical chemistry 1985;31(5):784-5.
1985: Marcovina S; Di Cola G; Rapetto C; Fievet C; Clavey V; Fruchart J C
Development of a radial immunodiffusion technique employing monoclonal antibodies for apolipoprotein B determination in human plasma.
Clinica chimica acta; international journal of clinical chemistry 1985;147(2):117-25.
1985: Fievet C; Parra H; Luyeye I; Demarquilly C; Fievet P; Fruchart J C; Bertrand M; Lablanche J M; Drouin P; Gross P
Mapping of lipoprotein particles with monoclonal antibodies in diabetes and atherosclerosis.
Monographs on atherosclerosis 1985;13():134-41.
1984: Fruchart J C; Fievet C; Ouvry D; Koffigan M; Beucler I; Ayrault-Jarrier M; Du Barry M; Marcovina S
Enzyme-linked immunoassay on microtitre plates for human apolipoprotein B.
La Ricerca in clinica e in laboratorio 1984;14(3):569-74.
1984: Bugugnani M J; Koffigan M; Kora I; Ouvry D; Clavey V; Fruchart J C
Rapid assessment of the distribution of apolipoproteins C-II and C-III subspecies in triglyceride-rich lipoproteins by isoelectric focusing.
Clinical chemistry 1984;30(3):349-51.
1984: Fievet C; Koffigan M; Ouvry D; Marcovina S; Moschetto Y; Fruchart J C
Noncompetitive enzyme-linked immunoassay for apolipoprotein B in serum.
Clinical chemistry 1984;30(1):98-100.
1984: Kora I; Vanhoutte G; Parra H; Bermann M C; Cachera C; Clavey V; Puchois P; Fruchart J C
[Assay of serum apolipoprotein A-II by electro-immunodiffusion on ready-for-use plates. Clinical applications]
Annales de biologie clinique 1984;42(5):349-53.
1983: Fruchart J C; Clavey V; Vanhoutte G
[Methods of biochemical analysis in hyperliproproteinemias]
Pathologie-biologie 1983;31(4):235-45.
1982: Parra H; Daunizeau A; Puchois P; Vanhoutte G; Fruchart J C
Evaluation of a method for quantitative serum lipoprotein analysis.
La Ricerca in clinica e in laboratorio 1982;12(1):173-80.
1982: Koffigan M; Fruchart J C; Dhondt J L; Moschetto Y; Farriaux J P
Apolipoprotein B measurement in blood spotted on paper (a screening test for familial type II A hyperlipoproteinemia).
La Ricerca in clinica e in laboratorio 1982;12(1):169-72.
1982: Fruchart J C; Kora I; Cachera C; Clavey V; Duthilleul P; Moschetto Y
Simultaneous measurement of plasma apolipoproteins A-I and B by electroimmunoassay.
Clinical chemistry 1982;28(1):59-62.
1981: Fruchart J C; Duthilleul P; Kora I; Duquesne M; Clavey V; Gentilini J L
Rapid determination of human plasma apolipoprotein B.
Clinica chimica acta; international journal of clinical chemistry 1981;114(1):123-6.

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